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Cellular Agriculture: Opportunities and Challenges. 细胞农业:机遇与挑战。
IF 12.4 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2021-03-25 DOI: 10.1146/annurev-food-063020-123940
Regine Eibl, Yannick Senn, Géraldine Gubser, Valentin Jossen, Christian van den Bos, Dieter Eibl

Cellular agriculture is the controlled and sustainable manufacture of agricultural products with cells and tissues without plant or animal involvement. Today, microorganisms cultivated in bioreactors already produce egg and milk proteins, sweeteners, and flavors for human nutrition as well as leather and fibers for shoes, bags, and textiles. Furthermore, plant cell and tissue cultures provide ingredients that stimulate the immune system and improve skin texture, with another precommercial cellular agriculture product, in vitro meat, currently receiving a great deal of attention. All these approaches could assist traditional agriculture in continuing to provide for the dietary requirements of a growing world population while freeing up important resources such as arable land. Despite early successes, challenges remain and are discussed in this review, with a focus on production processes involving plant and animal cell and tissue cultures.

细胞农业是在没有植物或动物参与的情况下,用细胞和组织控制和可持续地生产农产品。今天,在生物反应器中培养的微生物已经生产出鸡蛋和牛奶蛋白、甜味剂和人类营养的香料,以及用于鞋、袋和纺织品的皮革和纤维。此外,植物细胞和组织培养物提供了刺激免疫系统和改善皮肤质地的成分,另一种商业化的细胞农业产品,体外肉,目前受到了极大的关注。所有这些方法都可以帮助传统农业继续满足不断增长的世界人口的饮食需求,同时腾出耕地等重要资源。尽管取得了早期的成功,但挑战仍然存在,本文将重点讨论涉及植物和动物细胞和组织培养的生产过程。
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引用次数: 27
Food Matrix Effects for Modulating Starch Bioavailability. 调节淀粉生物利用度的食物基质效应。
IF 12.4 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2021-03-25 Epub Date: 2021-01-04 DOI: 10.1146/annurev-food-070620-013937
Ming Miao, Bruce R Hamaker

As the prevalence of obesity and diabetes has continued to increase rapidly in recent years, dietary approaches to regulating glucose homeostasis have gained more attention. Starch is the major source of glucose in the human diet and can have diverse effects, depending on its rate and extent of digestion in the small intestine, on postprandial glycemic response, which over time is associated with blood glucose abnormalities, insulin sensitivity, and even appetitive response and food intake. The classification of starch bioavailability into rapidly digestible starch, slowly digestible starch, and resistant starch highlights the nutritional values of different starches. As starch is the main structure-building macroconstituent of foods, its bioavailability can be manipulated by selection of food matrices with varying degrees of susceptibility to amylolysis and food processing to retain or develop new matrices. In this review, the food factors that may modulate starch bioavailability, with a focus on food matrices, are assessed for a better understanding of their potential contribution to human health. Aspects affecting starch nutritional properties as well as production strategies for healthy foods are also reviewed, e.g., starch characteristics (different type, structure, and modification), food physical properties (food form, viscosity, and integrity), food matrix interactions (lipid, protein, nonstarch polysaccharide, phytochemicals, organic acid, and enzyme inhibitor), and food processing (milling, cooking, and storage).

近年来,随着肥胖和糖尿病的患病率持续快速上升,饮食调节葡萄糖稳态的方法受到越来越多的关注。淀粉是人类饮食中葡萄糖的主要来源,根据其在小肠中的消化速度和程度,对餐后血糖反应有多种影响,随着时间的推移,血糖反应与血糖异常、胰岛素敏感性、甚至食欲反应和食物摄入有关。淀粉生物利用度分为快速消化淀粉、慢消化淀粉和抗性淀粉,突出了不同淀粉的营养价值。由于淀粉是食品的主要结构构建宏观成分,其生物利用度可以通过选择不同程度的淀粉水解易感性的食品基质和食品加工来控制,以保留或开发新的基质。在这篇综述中,评估了可能调节淀粉生物利用度的食物因素,重点是食物基质,以便更好地了解它们对人类健康的潜在贡献。影响淀粉营养特性以及健康食品生产策略的方面也进行了回顾,例如淀粉特性(不同类型、结构和改性)、食品物理特性(食品形式、粘度和完整性)、食品基质相互作用(脂质、蛋白质、非淀粉多糖、植物化学物质、有机酸和酶抑制剂)和食品加工(研磨、烹饪和储存)。
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引用次数: 35
Soy Protein: Molecular Structure Revisited and Recent Advances in Processing Technologies. 大豆蛋白:分子结构的重新审视和加工技术的最新进展。
IF 12.4 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2021-03-25 Epub Date: 2020-12-14 DOI: 10.1146/annurev-food-062220-104405
Xiaonan Sui, Tianyi Zhang, Lianzhou Jiang

Rising health concerns and increasing obesity levels in human society have led some consumers to cut back on animal protein consumption and switch to plant-based proteins as an alternative. Soy protein is a versatile protein supplement and contains well-balanced amino acids, making it comparable to animal protein. With sufficient processing and modification, the quality of soy protein can be improved above that of animal-derived proteins, if desired. The modern food industry is undergoing a dynamic change, with advanced processing technologies that can produce a multitude of foods and ingredients with functional properties from soy proteins, providing consumers with a wide variety of foods. This review highlights recent progress in soy protein processing technologies. Using the current literature, the processing-induced structural changes in soy protein are also explored. Furthermore, the molecular structure of soy protein, particularly the crystal structures of β-conglycinin and glycinin, is comprehensively revisited.

人类社会日益增长的健康担忧和日益严重的肥胖水平导致一些消费者减少了动物蛋白的消费,转而食用植物蛋白作为替代品。大豆蛋白是一种多用途的蛋白质补充剂,含有均衡的氨基酸,可与动物蛋白相媲美。通过充分的加工和改性,大豆蛋白的质量可以根据需要提高到动物源性蛋白的质量之上。现代食品工业正在经历一场动态的变革,先进的加工技术可以从大豆蛋白中生产出多种具有功能特性的食品和配料,为消费者提供了种类繁多的食品。本文综述了大豆蛋白加工技术的最新进展。利用现有的文献,还探讨了加工引起的大豆蛋白结构变化。此外,对大豆蛋白的分子结构,特别是β-甘氨酸和甘氨酸的晶体结构进行了全面的研究。
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引用次数: 82
The Passing of Todd Klaenhammer. 托德·克兰哈默的去世。
IF 12.4 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2021-03-25 DOI: 10.1146/annurev-fo-12-032421-100001
Michael P Doyle
It is with great sadness and a heavy heart that I write to inform you of the untimely passing of my dear friend and colleague, Todd Klaenhammer, who left us on March 6, 2021, following a brief hospitalization. Retired as a William Neal Reynolds Distinguished Professor of Food Science,Microbiology, andGenetics andUniversity Distinguished Professor at North Carolina State University, Todd was an eminent food microbiologist who revolutionized the study of bacterial probiotics and microbes associated with the fermentation of dairy products. His pioneering research led to the discovery of new bacteriocins, the development of phage-resistant lactic acid bacteria for fermenting cheese, and the application of probiotics to foods for health-promoting benefits.The ultimate recognition of the importance of his research contributions was his election to the US National Academy of Sciences in 2001. Todd wrote an autobiographical review titled “Get Cultured: Eat Bacteria” for Volume 10 of the Annual Review of Food Science and Technology that details many of his incredible career accomplishments. My association with Todd was largely through the Annual Review of Food Science and Technology, of which Todd and I were the founding Co-Editors As a bit of history, we were contacted in 2007 by the then Editor-in-Chief of Annual Reviews, Dr. Samuel Gubins, to develop a food science and technology–oriented journal for Annual Reviews. At the time, both Todd and I were fully occupied with many other professional commitments so we were not interested in taking on new opportunities. However, Sam was unrelenting and arranged for us to meet with him at a conference in Chicago where he put the full-court press on us to take on this new offering.With some reluctance we accepted Sam’s invitation and, with the involvement of an incredibly talented and highly esteemed Editorial Committee, we set off to chart the course for the Annual Review of Food Science and Technology, which is now at volume 12. Todd’s involvement in navigating the journal through a highly competitive publishing environment in which identifying and recruiting highly accomplished scientists to write timely review articles was incredible. Not only did he stay abreast of the leading developments in our field, but he was also well connected with the scientists who were paving the way, thereby enabling the acquisition of top-notch articles. We who have benefited from articles published in Annual Review of Food Science and Technology can in large part thank Todd for the contributions he made to developing the journal. Among his many awards, Todd received from the North Carolina University System the O. Max Gardner Award, which is given to a researcher “who has made the greatest contribution to the welfare of the human race.” I have no doubt that Todd is now in a better place where he will have an even greater impact promoting universally the application and benefits of probiotic microbes. Todd will be greatly missed
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引用次数: 0
Introduction. 介绍。
IF 12.4 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2021-03-25 DOI: 10.1146/annurev-fo-12-011221-100001
David Julian McClements
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引用次数: 0
Carotenoids: Considerations for Their Use in Functional Foods, Nutraceuticals, Nutricosmetics, Supplements, Botanicals, and Novel Foods in the Context of Sustainability, Circular Economy, and Climate Change. 类胡萝卜素:在可持续性、循环经济和气候变化背景下在功能性食品、营养保健品、营养化妆品、补充剂、植物药和新型食品中使用的考虑
IF 12.4 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2021-03-25 Epub Date: 2021-01-19 DOI: 10.1146/annurev-food-062220-013218
Antonio J Meléndez-Martínez, Volker Böhm, Grethe Iren Andersen Borge, M Pilar Cano, Martina Fikselová, Ruta Gruskiene, Vera Lavelli, Monica Rosa Loizzo, Anamarija I Mandić, Paula Mapelli Brahm, Aleksandra Č Mišan, Adela M Pintea, Jolanta Sereikaitė, Liliana Vargas-Murga, Sanja S Vlaisavljević, Jelena J Vulić, Nora M O'Brien

Carotenoids are versatile isoprenoids that are important in food quality and health promotion. There is a need to establish recommended dietary intakes/nutritional reference values for carotenoids. Research on carotenoids in agro-food and health is being propelled by the two multidisciplinary international networks, the Ibero-American Network for the Study of Carotenoids as Functional Foods Ingredients (IBERCAROT; http://www.cyted.org) and the European Network to Advance Carotenoid Research and Applications in Agro-Food and Health (EUROCAROTEN; http://www.eurocaroten.eu). In this review, considerations for their safe and sustainable use in products mostly intended for health promotion are provided. Specifically, information about sources, intakes, and factors affecting bioavailability is summarized. Furthermore, their health-promoting actions and importance in public health in relation to the contribution of reducing the risk of diverse ailments are synthesized. Definitions and regulatory and safety information for carotenoid-containing products are provided. Lastly, recent trends in research in the context of sustainable healthy diets are summarized.

类胡萝卜素是多功能的类异戊二烯,对食品质量和促进健康很重要。有必要确定类胡萝卜素的推荐膳食摄入量/营养参考值。两个多学科国际网络正在推动农业食品和保健方面的类胡萝卜素研究,即伊比利亚-美洲作为功能性食品成分的类胡萝卜素研究网络(IBERCAROT;http://www.cyted.org)和欧洲促进类胡萝卜素在农业食品和健康方面的研究和应用网络(EUROCAROTEN;http://www.eurocaroten.eu)。在这篇综述中,对它们在主要用于促进健康的产品中的安全和可持续使用提出了考虑。具体地,信息的来源,摄入量和影响生物利用度的因素进行了总结。此外,还综合介绍了它们在促进健康方面的行动以及在减少各种疾病风险方面对公共卫生的重要性。提供了类胡萝卜素产品的定义、监管和安全信息。最后,总结了可持续健康饮食研究的最新趋势。
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引用次数: 62
Alternative Protein Sources as Technofunctional Food Ingredients. 作为技术功能性食品成分的替代蛋白质来源。
IF 12.4 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2021-03-25 Epub Date: 2021-01-20 DOI: 10.1146/annurev-food-062520-093642
Lutz Grossmann, Jochen Weiss

Proteins obtained from alternative sources such as plants, microorganisms, and insects have attracted considerable interest in the formulation of new food products that have a lower environmental footprint and offer means to feed a growing world population. In contrast to many established proteins, and protein fractions for which a substantial amount of knowledge has accumulated over the years, much less information is available on these emerging proteins. This article reviews the current state of knowledge on alternative proteins and their sources, highlighting gaps that currently pose obstacles to their more widespread application in the food industry. The compositional, structural, and functional properties of alternative proteins from various sources, including plants, algae, fungi, and insects, are critically reviewed. In particular, we focus on the factors associated with the creation of protein-rich functional ingredients from alternative sources. The various protein fractions in these sources are described as well as their behavior under different environmental conditions (e.g., pH, ionic strength, and temperature). The extraction approaches available to produce functional protein ingredients from these alternative sources are introduced as well as challenges associated with designing large-scale commercial processes. The key technofunctional properties of alternative proteins, such as solubility, interfacial activity, emulsification, foaming, and gelation properties, are introduced. In particular, we focus on the formation of isotropic and anisotropic structures suitablefor creating meat and dairy product analogs using various structuring techniques. Finally, selected studies on consumer acceptance and sustainability of alternative protein products are considered.

从植物、微生物和昆虫等替代来源获得的蛋白质引起了人们对新型食品配方的极大兴趣,这些食品对环境的影响较小,并为不断增长的世界人口提供了养活手段。与许多已建立的蛋白质和多年来积累了大量知识的蛋白质组分相比,这些新兴蛋白质的信息要少得多。本文回顾了目前关于替代蛋白质及其来源的知识状况,强调了目前阻碍其在食品工业中更广泛应用的差距。从各种来源,包括植物,藻类,真菌和昆虫的替代蛋白质的组成,结构和功能特性,严格审查。特别是,我们关注与从替代来源创造富含蛋白质的功能成分相关的因素。描述了这些来源中的各种蛋白质组分以及它们在不同环境条件下的行为(例如,pH值,离子强度和温度)。介绍了可用于从这些替代来源生产功能性蛋白质成分的提取方法以及与设计大规模商业流程相关的挑战。介绍了替代蛋白的关键技术功能特性,如溶解度、界面活性、乳化性、发泡性和凝胶性。特别是,我们专注于各向同性和各向异性结构的形成,适用于使用各种结构技术创建肉类和乳制品类似物。最后,选择研究消费者接受和可持续性的替代蛋白质产品进行了考虑。
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引用次数: 59
Emerging Applications of Machine Learning in Food Safety. 机器学习在食品安全中的新兴应用。
IF 12.4 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2021-03-25 Epub Date: 2021-01-20 DOI: 10.1146/annurev-food-071720-024112
Xiangyu Deng, Shuhao Cao, Abigail L Horn

Food safety continues to threaten public health. Machine learning holds potential in leveraging large, emerging data sets to improve the safety of the food supply and mitigate the impact of food safety incidents. Foodborne pathogen genomes and novel data streams, including text, transactional, and trade data, have seen emerging applications enabled by a machine learning approach, such as prediction of antibiotic resistance, source attribution of pathogens, and foodborne outbreak detection and risk assessment. In this article, we provide a gentle introduction to machine learning in the context of food safety and an overview of recent developments and applications. With many of these applications still in their nascence, general and domain-specific pitfalls and challenges associated with machine learning have begun to be recognized and addressed, which are critical to prospective use and future deployment of large data sets and their associated machine learning models for food safety applications.

食品安全继续威胁着公众健康。机器学习在利用大型新兴数据集来提高食品供应的安全性和减轻食品安全事件的影响方面具有潜力。食源性病原体基因组和新的数据流,包括文本、交易和贸易数据,已经通过机器学习方法实现了新兴应用,例如抗生素耐药性预测、病原体来源归因以及食源性疫情检测和风险评估。在本文中,我们简要介绍了食品安全背景下的机器学习,并概述了最近的发展和应用。由于许多这些应用仍处于起步阶段,与机器学习相关的一般和特定领域的陷阱和挑战已经开始被认识和解决,这对于大型数据集及其相关机器学习模型在食品安全应用中的前瞻性使用和未来部署至关重要。
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引用次数: 41
Effect of Food Processing on Antioxidant Potential, Availability, and Bioavailability. 食品加工对抗氧化潜力、利用度和生物利用度的影响。
IF 12.4 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2021-03-25 Epub Date: 2021-01-25 DOI: 10.1146/annurev-food-062420-105140
Martha Verghese, Shantrell Willis, Judith Boateng, Ahmed Gomaa, Rajwinder Kaur

Antioxidants are understood to play a key role in disease prevention; because of this, research and interest in these compounds are ever increasing. Antioxidative phytochemicals from natural sources are preferred, as some negative implications have been associated with synthetic antioxidants. Beans, nuts, seeds, fruits, and vegetables, to name a few, are important sources of phytochemicals, which have purported health benefits. The aforementioned plant sources are reportedly rich in bioactive compounds, most of which undergo some form of processing (boiling, steaming, soaking) prior to consumption. This article briefly reviews selected plants (beans, nuts, seeds, fruits, and vegetables) and the effects of processing on the antioxidant potential, availability, and bioavailability of phytochemicals, with research from our laboratory and other studies determining the health benefits of and processing effects on bioactive compounds.

抗氧化剂在疾病预防中发挥着关键作用;正因为如此,对这些化合物的研究和兴趣不断增加。天然来源的抗氧化植物化学物质是首选,因为一些负面影响与合成抗氧化剂有关。豆类、坚果、种子、水果和蔬菜,仅举几例,都是植物化学物质的重要来源,据称对健康有益。据报道,上述植物来源富含生物活性化合物,其中大多数在食用前经过某种形式的加工(煮沸,蒸煮,浸泡)。本文简要回顾了选定的植物(豆类、坚果、种子、水果和蔬菜),以及加工对植物化学物质的抗氧化潜力、可利用性和生物利用度的影响,以及我们实验室和其他研究确定的健康益处和加工对生物活性化合物的影响。
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引用次数: 8
Opportunities and Challenges for the Introduction of New Food Proteins. 引进新食物蛋白质的机遇与挑战。
IF 12.4 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2021-03-25 Epub Date: 2021-01-05 DOI: 10.1146/annurev-food-061220-012838
Richard A Williams
New forms of protein are being developed at a rapid rate as older forms of protein, particularly meat and poultry, are coming under attack for nutritional, environmental, food safety, and animal welfare issues. To date, the FDA and USDA have split oversight of the new technologies that include genetic engineering and precision fermentation. Because these new products address the problems associated with traditional proteins, consumer demand appears to be overcoming fundamental fears associated with innovative foods. Currently, agencies are struggling with naming issues for the new proteins and, in some cases, possibly being forced to use costly and lengthy premarket approvals. Because of the complexity of new production methods, the speed of development, and the potential benefits, a new system of regulation may be necessary. It would consist of one of the existing agencies becoming a super regulator overseeing private companies that specialize and compete with each other and are regulated quickly and competently. Expected final online publication date for the Annual Review of Food Science and Technology, Volume 12 is March 2021. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.
新形式的蛋白质正在迅速发展,而旧形式的蛋白质,特别是肉类和家禽,正受到营养、环境、食品安全和动物福利问题的攻击。迄今为止,FDA和USDA对包括基因工程和精密发酵在内的新技术进行了分开监管。由于这些新产品解决了与传统蛋白质有关的问题,消费者的需求似乎正在克服与创新食品有关的根本恐惧。目前,各机构正在努力解决新蛋白质的命名问题,在某些情况下,可能被迫使用昂贵而漫长的上市前批准。由于新的生产方法的复杂性、发展速度和潜在的好处,一个新的监管体系可能是必要的。它将由一个现有机构组成,成为一个超级监管机构,监督那些专业化、相互竞争、监管迅速而有效的私营公司。
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引用次数: 8
期刊
Annual review of food science and technology
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