Qutabuddin Khuhro, M. Asghar, A. Majeed, Hafeezullah Shaikh, Shobha Luxmi, Abubakar Tauseef, Maryam Zafar Uzma Rasheed, M. Siddiqui, S. Aslam
Here we present a case of concomitant pancreatitis and cholangitis in a young female patient with culture-proven Salmonella Typhi in the blood which was sensitive to Meropenem and Azithromycin only. The multiple drug-resistant strain of Salmonella Typhi can lead to serious complications as was present in our case. The resistance is acquired by alteration in the genome sequence. Currently, control of such an unknown outbreak of Salmonella Typhi's multiple drug-resistant strains are important, since it is a serious healthcare issue in disease control and prevention of endemic countries.
{"title":"Enteric Fever with Concomitant Pancreatitis and Cholangitis. A Case Report-Based Review of the Literature","authors":"Qutabuddin Khuhro, M. Asghar, A. Majeed, Hafeezullah Shaikh, Shobha Luxmi, Abubakar Tauseef, Maryam Zafar Uzma Rasheed, M. Siddiqui, S. Aslam","doi":"10.26502/aimr.0016","DOIUrl":"https://doi.org/10.26502/aimr.0016","url":null,"abstract":"Here we present a case of concomitant pancreatitis and cholangitis in a young female patient with culture-proven Salmonella Typhi in the blood which was sensitive to Meropenem and Azithromycin only. The multiple drug-resistant strain of Salmonella Typhi can lead to serious complications as was present in our case. The resistance is acquired by alteration in the genome sequence. Currently, control of such an unknown outbreak of Salmonella Typhi's multiple drug-resistant strains are important, since it is a serious healthcare issue in disease control and prevention of endemic countries.","PeriodicalId":8282,"journal":{"name":"Archives of Internal Medicine Research","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86824191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: The purpose of this study is to evaluate the clinical outcomes of non-surgical periodontal therapy specifically for psychiatric, diabetic, nephropathic and gastrointestinal patients. The clinical presentation of the diseases of these patients is followed by the selection of some of the patient typologies according to the above classification, followed by the documented evaluation of the periodontal prior status and 1 week of non-surgical periodontal non-surgical posttraumatic treatment. Materials and methods: The study was conducted in a total of 311 patients, out of which 206 were ill patients included in the assessment, of which 80 were cardiac patients, 76 diabetic patients, 43 nephropathic patients, 7 gastrointestinal patients included in the study ours, after meeting the inclusion criteria. Patients included in the study are divided by age, sex and socio-health status. Results: Outcome results in delayed treatment in diabetic patients with oral cavity injuries. The minimum amount of bacterial plaque in patients with gastrointestinal diseases is the most typical element of this category. The appearance of gingival hypertrophy in patients with hypertension treated with calcium-blockers and the faintest gingivitis during treatment of nephropathy patients are the typical features found in the relevant patient category. Patient's vulnerability to combinations of diseases that follow and encourage each other was higher in the cardiac and diabetic relationship than in nephropathy and diabetes patients. Cardiac patients, if we talk about the healing process, in the probability values, reacted more slowly than diabetic patients. This element should be further followed by further analysis of the risk factors of these categories versus the occurrence of periodontal diseases. Conclusions: The hemorrhage index expressed significant reductions during the healing process, in descending order, the highest changes in diabetic patients, followed in gastrointestinal, nephropathic patients and the last were cardiac patients. Systemic diseases are directly related to the periodontal status of patients affected by them. This connection is secondary because, as the systemic diseases cause periodontal disease, the later path is also worthwhile, since periodontal diseases also cause systemic diseases, which even endanger the patient's life.
{"title":"The Effect of Conservative Periodontal Therapy at Patients with Systemic Diseases","authors":"Ilma Robo, Saimir Heta, Fjona Hamzai, V. Ostreni","doi":"10.26502/aimr.0010","DOIUrl":"https://doi.org/10.26502/aimr.0010","url":null,"abstract":"Introduction: The purpose of this study is to evaluate the clinical outcomes of non-surgical periodontal therapy specifically for psychiatric, diabetic, nephropathic and gastrointestinal patients. The clinical presentation of the diseases of these patients is followed by the selection of some of the patient typologies according to the above classification, followed by the documented evaluation of the periodontal prior status and 1 week of non-surgical periodontal non-surgical posttraumatic treatment. Materials and methods: The study was conducted in a total of 311 patients, out of which 206 were ill patients included in the assessment, of which 80 were cardiac patients, 76 diabetic patients, 43 nephropathic patients, 7 gastrointestinal patients included in the study ours, after meeting the inclusion criteria. Patients included in the study are divided by age, sex and socio-health status. Results: Outcome results in delayed treatment in diabetic patients with oral cavity injuries. The minimum amount of bacterial plaque in patients with gastrointestinal diseases is the most typical element of this category. The appearance of gingival hypertrophy in patients with hypertension treated with calcium-blockers and the faintest gingivitis during treatment of nephropathy patients are the typical features found in the relevant patient category. Patient's vulnerability to combinations of diseases that follow and encourage each other was higher in the cardiac and diabetic relationship than in nephropathy and diabetes patients. Cardiac patients, if we talk about the healing process, in the probability values, reacted more slowly than diabetic patients. This element should be further followed by further analysis of the risk factors of these categories versus the occurrence of periodontal diseases. Conclusions: The hemorrhage index expressed significant reductions during the healing process, in descending order, the highest changes in diabetic patients, followed in gastrointestinal, nephropathic patients and the last were cardiac patients. Systemic diseases are directly related to the periodontal status of patients affected by them. This connection is secondary because, as the systemic diseases cause periodontal disease, the later path is also worthwhile, since periodontal diseases also cause systemic diseases, which even endanger the patient's life.","PeriodicalId":8282,"journal":{"name":"Archives of Internal Medicine Research","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90791563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: MPA (or microscopic polyarteritis) is clinically described as patients with exclusively nongranulomatous small vessel vasculitis involving the upper or lower respiratory tract (e.g., alveolar capillaritis). The most common manifestation of MPA is necrotizing glomerulonephritis and/or pulmonary capillaritis. Serologically, more than 90% of MPA patients have a positive antineutrophil cytoplasmic antibodies (ANCA). There have been selective case reports documenting pancytopenia associated with vasculitis. Case: Here, we discuss a 56 year old female patient who presented with pancytopenia, and was found to have biopsy-proven small vessel vasculitis with negative ANCA. She presented with 5-6 weeks of worsening generalized fatigue, cough with hemoptysis, intermittent fever, and shortness of breath on exertion and weight loss of 8lbs over this time. On presentation, she was febrile (102F) and found to have pancytopenia, with normal kidney function. She was admitted to the Intensive Care Unit for a presumed viral illness and underwent a bone marrow biopsy for evaluation of pancytopenia. Further imaging with computerized tomography (CT) scan demonstrated ground glass haziness. Bone marrow biopsy revealed normal results. She was discharged with the diagnosis of a pancytopenic viral illness. She returned 4 weeks later with worsening of her symptoms. CT chest showed significant interval changes compared to previous CT with bilateral ground glass opacities. Lung biopsy was performed which showed small vessel vasculitis. Repeat CT chest following steroid treatment demonstrated significant improvement. Discussion: To our knowledge, this is the first reported case of pancytopenia in small vessel vasculitis not associated with lupus. In cases of MPA, 96% are ANCA positive. However, this patient fits into the criteria of ANCA-negative vasculitis. Although ILD is an uncommon presentation of MPA, there have been an increasing number of cases citing association of vasculitis with ILD. In conclusion, vasculitis associated with pancytopenia continues to be poorly understood. ANCA negativity at the time of presentation can give a false sense of security and delay treatment.
{"title":"ANCA Negative Vasculitis Presenting with Interstitial Lung Disease and Pancytopenia","authors":"Kriti Gupta, Behtash Saeidi, W. Pascal","doi":"10.26502/aimr.0015","DOIUrl":"https://doi.org/10.26502/aimr.0015","url":null,"abstract":"Introduction: MPA (or microscopic polyarteritis) is clinically described as patients with exclusively nongranulomatous small vessel vasculitis involving the upper or lower respiratory tract (e.g., alveolar capillaritis). The most common manifestation of MPA is necrotizing glomerulonephritis and/or pulmonary capillaritis. Serologically, more than 90% of MPA patients have a positive antineutrophil cytoplasmic antibodies (ANCA). There have been selective case reports documenting pancytopenia associated with vasculitis. Case: Here, we discuss a 56 year old female patient who presented with pancytopenia, and was found to have biopsy-proven small vessel vasculitis with negative ANCA. She presented with 5-6 weeks of worsening generalized fatigue, cough with hemoptysis, intermittent fever, and shortness of breath on exertion and weight loss of 8lbs over this time. On presentation, she was febrile (102F) and found to have pancytopenia, with normal kidney function. She was admitted to the Intensive Care Unit for a presumed viral illness and underwent a bone marrow biopsy for evaluation of pancytopenia. Further imaging with computerized tomography (CT) scan demonstrated ground glass haziness. Bone marrow biopsy revealed normal results. She was discharged with the diagnosis of a pancytopenic viral illness. She returned 4 weeks later with worsening of her symptoms. CT chest showed significant interval changes compared to previous CT with bilateral ground glass opacities. Lung biopsy was performed which showed small vessel vasculitis. Repeat CT chest following steroid treatment demonstrated significant improvement. Discussion: To our knowledge, this is the first reported case of pancytopenia in small vessel vasculitis not associated with lupus. In cases of MPA, 96% are ANCA positive. However, this patient fits into the criteria of ANCA-negative vasculitis. Although ILD is an uncommon presentation of MPA, there have been an increasing number of cases citing association of vasculitis with ILD. In conclusion, vasculitis associated with pancytopenia continues to be poorly understood. ANCA negativity at the time of presentation can give a false sense of security and delay treatment.","PeriodicalId":8282,"journal":{"name":"Archives of Internal Medicine Research","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83101386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Efficacy of the Berlin Questionnaire and the Epworth Sleepiness Scale in Obstructive Sleep Apnea","authors":"Ibrahim Güven Çosgun, A. Balcı","doi":"10.26502/aimr.0143","DOIUrl":"https://doi.org/10.26502/aimr.0143","url":null,"abstract":"","PeriodicalId":8282,"journal":{"name":"Archives of Internal Medicine Research","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85478160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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