首页 > 最新文献

Archives of otolaryngology--head & neck surgery最新文献

英文 中文
Larynx cancer: search for molecular markers 喉癌:寻找分子标记
Pub Date : 2019-01-01 DOI: 10.4322/ahns.2019.0009
D. Figueiredo, Bárbara Mendes Paz Chao, Felipe da Silva Figueiredo
Rafaela de Barros e Lima Bueno1,2, Anelisa Ramão1,2, Daniel Guariz Pinheiro3, Cleidson Padua Alves2,4, Vinicius Kannen5, Achim Jungbluth6, Luiza Ferreira de Araújo1,2,4, Bruna Rodrigues Muys1,2, Aline Simoneti Fonseca1,2,4, Jessica Rodrigues Plaça2,4, Bárbara Mendes Paz Chao7, Felipe da Silva Figueiredo8, Rodrigo Alexandre Panepucci2, Luciano Neder5, Fabiano Saggioro5, Rui Celso Martins Mamede9, David Livingstone Alves Figueiredo7*, Wilson Araújo Silva Junior1,2,4,10 1Universidade de São Paulo, Faculdade de Medicina, Departamento de Genética, Ribeirão Preto, SP, Brasil 2Instituto Nacional de Ciência e tecnologia, células tronco e centro de terapia celular. Ribeirão Preto, São Paulo, Brasil 3Universidade Estadual Paulista (UNESP), Faculdade de agricultura e Ciências Veterinárias, Departamento de tecnologia, Jaboticabal, SP, Brasil 4Centro de Sistema Biológicos integrados, CISBi, NAP/USP, Ribeirão Preto, SP, Brasil 5Universidade de São Paulo, Faculdade de Medicina, Departamento de Patologia, Ribeirão Preto, SP, Brasil 6Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, United States of America 7Universidade Estadual do Centro Oeste – UNICENTRO, Guarapuava, PR, Brasil 8Pontifícia Universidade Católica, Departamento de Medicina, Curitiba, PR, Brasil 9Universidade de São Paulo, Faculdade de Medicina, Departamento de oftalmologia, otorrinolaringologia e Cirurgia de cabeça e pescoço, Ribeirão Preto, SP, Brasil 10Centro Regional de Hemoterapia de Ribeirão Preto, Ribeirão Preto, SP, Brasil
“•德利马和Bueno1 2 Anelisa Ramão1 2丹尼尔Guariz Pinheiro3 Cleidson帕多瓦Alves2 4、马可士Kannen5 Achim Jungbluth6路易莎·Araújo1, 2, 4,罗德里格斯Muys1命中,2,艾琳Simoneti Fonseca1, 2, 4,杰西卡·罗德里格斯Plaça2 Chao7和平,芭芭拉·门德斯,菲利普•达席尔瓦Figueiredo8卢西亚诺Neder5罗德里戈·亚历山大Panepucci2 Saggioro5粒入球,瑞克马丁斯Mamede9,大卫•利文斯敦阿尔维斯Figueiredo7 * Wilson araujo席尔瓦Junior1第1、2、4、10圣保罗大学,医学院,遗传学系,ribeirao Preto, SP,巴西2国家科学技术研究所,干细胞和细胞治疗中心。巴西,圣保罗,巴西圣保罗州立大学(流),农业和兽医学院,Jaboticabal SP技术部门,巴西四中心系统有机集成,CISBi ntl / USP、巴西黑SP,巴西圣保罗5大学医学院病理学系的黑色SP、巴西,巴西6病理学系,纽约纪念斯隆-凯特琳癌症中心,美利坚合众国7的中西部州立大学—UNICENTRO出生的,因此,巴西八宗天主教大学医学系,库里提巴,因此,巴西圣保罗9大学医学院,眼科,耳鼻喉科学部门和头颈部手术、巴西黑SP,巴西10 Hemoterapia区域中心城市、巴西黑,小溪,高层
{"title":"Larynx cancer: search for molecular markers","authors":"D. Figueiredo, Bárbara Mendes Paz Chao, Felipe da Silva Figueiredo","doi":"10.4322/ahns.2019.0009","DOIUrl":"https://doi.org/10.4322/ahns.2019.0009","url":null,"abstract":"Rafaela de Barros e Lima Bueno1,2, Anelisa Ramão1,2, Daniel Guariz Pinheiro3, Cleidson Padua Alves2,4, Vinicius Kannen5, Achim Jungbluth6, Luiza Ferreira de Araújo1,2,4, Bruna Rodrigues Muys1,2, Aline Simoneti Fonseca1,2,4, Jessica Rodrigues Plaça2,4, Bárbara Mendes Paz Chao7, Felipe da Silva Figueiredo8, Rodrigo Alexandre Panepucci2, Luciano Neder5, Fabiano Saggioro5, Rui Celso Martins Mamede9, David Livingstone Alves Figueiredo7*, Wilson Araújo Silva Junior1,2,4,10 1Universidade de São Paulo, Faculdade de Medicina, Departamento de Genética, Ribeirão Preto, SP, Brasil 2Instituto Nacional de Ciência e tecnologia, células tronco e centro de terapia celular. Ribeirão Preto, São Paulo, Brasil 3Universidade Estadual Paulista (UNESP), Faculdade de agricultura e Ciências Veterinárias, Departamento de tecnologia, Jaboticabal, SP, Brasil 4Centro de Sistema Biológicos integrados, CISBi, NAP/USP, Ribeirão Preto, SP, Brasil 5Universidade de São Paulo, Faculdade de Medicina, Departamento de Patologia, Ribeirão Preto, SP, Brasil 6Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, United States of America 7Universidade Estadual do Centro Oeste – UNICENTRO, Guarapuava, PR, Brasil 8Pontifícia Universidade Católica, Departamento de Medicina, Curitiba, PR, Brasil 9Universidade de São Paulo, Faculdade de Medicina, Departamento de oftalmologia, otorrinolaringologia e Cirurgia de cabeça e pescoço, Ribeirão Preto, SP, Brasil 10Centro Regional de Hemoterapia de Ribeirão Preto, Ribeirão Preto, SP, Brasil","PeriodicalId":8285,"journal":{"name":"Archives of otolaryngology--head & neck surgery","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90804931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Brave new world. 美丽的新世界。
Pub Date : 2018-06-18 DOI: 10.1787/9b181d3c-en
R. Jackler
{"title":"Brave new world.","authors":"R. Jackler","doi":"10.1787/9b181d3c-en","DOIUrl":"https://doi.org/10.1787/9b181d3c-en","url":null,"abstract":"","PeriodicalId":8285,"journal":{"name":"Archives of otolaryngology--head & neck surgery","volume":"4 1","pages":"471-2"},"PeriodicalIF":0.0,"publicationDate":"2018-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72592032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In Memoriam: Paul H. Ward, MD (1928-2015) 纪念:保罗·h·沃德,医学博士(1928-2015)
Pub Date : 2015-08-01 DOI: 10.1001/JAMAOTO.2015.1206
R. Cantrell
{"title":"In Memoriam: Paul H. Ward, MD (1928-2015)","authors":"R. Cantrell","doi":"10.1001/JAMAOTO.2015.1206","DOIUrl":"https://doi.org/10.1001/JAMAOTO.2015.1206","url":null,"abstract":"","PeriodicalId":8285,"journal":{"name":"Archives of otolaryngology--head & neck surgery","volume":"21 1","pages":"683-683"},"PeriodicalIF":0.0,"publicationDate":"2015-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73197068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Trainee’s Reflection of Paul H. Ward, MD 实习生对Paul H. Ward医学博士的反思
Pub Date : 2015-08-01 DOI: 10.1001/JAMAOTO.2015.1202
G. Berke
{"title":"A Trainee’s Reflection of Paul H. Ward, MD","authors":"G. Berke","doi":"10.1001/JAMAOTO.2015.1202","DOIUrl":"https://doi.org/10.1001/JAMAOTO.2015.1202","url":null,"abstract":"","PeriodicalId":8285,"journal":{"name":"Archives of otolaryngology--head & neck surgery","volume":"36 1","pages":"684-684"},"PeriodicalIF":0.0,"publicationDate":"2015-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87691256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
What Makes Us Different?: Unique Opportunities When You Publish in JAMA Otolaryngology–Head & Neck Surgery 是什么让我们与众不同?:发表在JAMA耳鼻咽喉头颈外科杂志上的独特机会
Pub Date : 2015-03-01 DOI: 10.1001/JAMAOTO.2015.0224
P. Levine
{"title":"What Makes Us Different?: Unique Opportunities When You Publish in JAMA Otolaryngology–Head & Neck Surgery","authors":"P. Levine","doi":"10.1001/JAMAOTO.2015.0224","DOIUrl":"https://doi.org/10.1001/JAMAOTO.2015.0224","url":null,"abstract":"","PeriodicalId":8285,"journal":{"name":"Archives of otolaryngology--head & neck surgery","volume":"130 1","pages":"201-201"},"PeriodicalIF":0.0,"publicationDate":"2015-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76174979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In Memoriam: Charles W. Vaughan, MD (1926-2014) 纪念:查尔斯·w·沃恩,医学博士(1926-2014)
Pub Date : 2014-08-01 DOI: 10.1001/JAMAOTO.2014.1180
K. Grundfast
{"title":"In Memoriam: Charles W. Vaughan, MD (1926-2014)","authors":"K. Grundfast","doi":"10.1001/JAMAOTO.2014.1180","DOIUrl":"https://doi.org/10.1001/JAMAOTO.2014.1180","url":null,"abstract":"","PeriodicalId":8285,"journal":{"name":"Archives of otolaryngology--head & neck surgery","volume":"4 1","pages":"697-697"},"PeriodicalIF":0.0,"publicationDate":"2014-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80997284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In Memoriam: William F. House, DDS, MD, the “Father of Neurotology” (1923-2012) 纪念:威廉·f·豪斯,DDS,医学博士,“神经学之父”(1923-2012)
Pub Date : 2013-02-01 DOI: 10.1001/JAMAOTO.2013.51
K. Berliner
{"title":"In Memoriam: William F. House, DDS, MD, the “Father of Neurotology” (1923-2012)","authors":"K. Berliner","doi":"10.1001/JAMAOTO.2013.51","DOIUrl":"https://doi.org/10.1001/JAMAOTO.2013.51","url":null,"abstract":"","PeriodicalId":8285,"journal":{"name":"Archives of otolaryngology--head & neck surgery","volume":"429 1","pages":"202-203"},"PeriodicalIF":0.0,"publicationDate":"2013-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78192574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Our Thanks to Peer Reviewers 2011-2012 我们感谢同行评审2011-2012
Pub Date : 2012-12-01 DOI: 10.1001/JAMAOTO.2013.1452
P. Levine
Elliot Abemayor* Amit Agrawal Sumit Agrawal Yuri Agrawal Ashley Aiken Petra Ambrosch Aleodor Andea Peter E. Andersen Brian Andrews Patrick J. Antonelli Ellis Arjmand William B. Armstrong Joseph Aulino Utku Aydil Cristina Baldassari Manohar Bance Michael Barakate Maurizio Barbara Nancy M. Bauman Nigel Beasley Samuel Becker Joshua Bedwell Andrew Bellizzi John P. Bent Gerald S. Berke Robert G. Berkowitz Naveen Bhandarkar Neil Bhattacharyya Carol Bier-Laning Steven Billings Jennifer Black Nikolas Blevins Joel H. Blumin Charles Bower Holly Boyer Carol R. Bradford* Helen Branson Barton F. Branstetter Scott Evans Brietzke Matthew Brigger Louis Brill Jan Brunings Grant Bullock Brian Burkey Bruce H. Campbell Thomas Carey William Carroll Roy Casiano Claudio Roberto Cernea Kenny H. Chan Sudipta Chandra Philip Chapman Amy Y. Chen Rebecca D. Chernock Sukgi S. Choi* Daniel I. Choo Asim Choudhri Jared Christophel Robert Chun Deborah J. Chute Daniel Coelho James I. Cohen Noel Cohen Seth Cohen William Collins Maura Cosetti Mary Cunnane Michael Cunningham Joel Cure Joseph Curry Sharon Cushing Sam Daniel David H. Darrow Subinoy Das Bruce J. Davidson Alessandro DeAlarcon Jennifer Derebery Daniel G. Deschler Vikram Deshpande Jolien Desmet Anand Devaiah Margaret Dillon Guo Qiang Ding Robert Dobie Joseph Dohar Karen Doyle Amelia F. Drake Alfred Dreher David W. Eisele Marc D. Eisen Lisa Elden Hamdy El-Hakim Ravindhra G. Elluru Charles Elmaraghy Kevin Emerick Ramon Esclamado William C. Faquin D. Gregory Farwell Girish Fatterpekar Jose Fayad Pierre Fayoux Robert Louis Ferris Paul Flint Andrew S. Florea Marvin P. Fried* Paul Louis Friedlander Ellen M. Friedman Rick A. Friedman Henry Frierson Patrick Froehlich Nabil Fuleihan Thomas J. Gal Ian Ganly Bruce J. Gantz* Noel Garabedian C. Gaelyn Garrett Soha Ghossaini Ziv Gil Daniel Ginat Lyon L. Gleich George S. Goding Joel Goebel Whitney Goldner Nira Goldstein Mitchell Gore Christine G. Gourin Alberto Grammatica Stacey Gray John Herman Greinwald Neil Gross Kenneth Grundfast Christian Guilleminault Arsheed Hakeem Earl H. Harley Christopher J. Hartnick George Hashisaki David Haynes Kevin C. Hazen Keith S. Heller Peter Hilger Henry Hoffman F. Christopher Holsinger Benjamin Huang Julia C. Iezzoni Brandon Isaacson Lisa Ishii Stacey Ishman Robert Jackler Ian N. Jacobs Rajan Jain Mark J. Jameson* Herman Jenkins Anita Jeyakumar Vickie Jo Carl Johnson Benjamin Judson Shin-ichi Kanemaru Kian Karimi Lucy Karnell David M. Kaylie Robert Kellman Margaret Kenna Bradley W. Kesser* Eric Kezirian Ayesha Khalid Ana Kim Michael Kim Claudia Kirsch Daniel Kirse Bernadette Koch Wayne Koch Peter Koltai Christina Kong Paul Krakovitz Dennis Kraus Piotr Kurnatowski David Kutler Joe Kutz Stephen Y. Lai Anil K. Lalwani* David Larson Daniel Lee Robin D. Legallo Benjamin Leiss Marci M. Lesperance* James S. Lewis Greg Licameli Judith E. C. Lieu Derrick T. Lin Todd Loehrl Brenda Lonsbury-Martin M. Beatriz Lopes Robert Lorenz Lawrence Lustig William M. Lydiatt*
{"title":"Our Thanks to Peer Reviewers 2011-2012","authors":"P. Levine","doi":"10.1001/JAMAOTO.2013.1452","DOIUrl":"https://doi.org/10.1001/JAMAOTO.2013.1452","url":null,"abstract":"Elliot Abemayor* Amit Agrawal Sumit Agrawal Yuri Agrawal Ashley Aiken Petra Ambrosch Aleodor Andea Peter E. Andersen Brian Andrews Patrick J. Antonelli Ellis Arjmand William B. Armstrong Joseph Aulino Utku Aydil Cristina Baldassari Manohar Bance Michael Barakate Maurizio Barbara Nancy M. Bauman Nigel Beasley Samuel Becker Joshua Bedwell Andrew Bellizzi John P. Bent Gerald S. Berke Robert G. Berkowitz Naveen Bhandarkar Neil Bhattacharyya Carol Bier-Laning Steven Billings Jennifer Black Nikolas Blevins Joel H. Blumin Charles Bower Holly Boyer Carol R. Bradford* Helen Branson Barton F. Branstetter Scott Evans Brietzke Matthew Brigger Louis Brill Jan Brunings Grant Bullock Brian Burkey Bruce H. Campbell Thomas Carey William Carroll Roy Casiano Claudio Roberto Cernea Kenny H. Chan Sudipta Chandra Philip Chapman Amy Y. Chen Rebecca D. Chernock Sukgi S. Choi* Daniel I. Choo Asim Choudhri Jared Christophel Robert Chun Deborah J. Chute Daniel Coelho James I. Cohen Noel Cohen Seth Cohen William Collins Maura Cosetti Mary Cunnane Michael Cunningham Joel Cure Joseph Curry Sharon Cushing Sam Daniel David H. Darrow Subinoy Das Bruce J. Davidson Alessandro DeAlarcon Jennifer Derebery Daniel G. Deschler Vikram Deshpande Jolien Desmet Anand Devaiah Margaret Dillon Guo Qiang Ding Robert Dobie Joseph Dohar Karen Doyle Amelia F. Drake Alfred Dreher David W. Eisele Marc D. Eisen Lisa Elden Hamdy El-Hakim Ravindhra G. Elluru Charles Elmaraghy Kevin Emerick Ramon Esclamado William C. Faquin D. Gregory Farwell Girish Fatterpekar Jose Fayad Pierre Fayoux Robert Louis Ferris Paul Flint Andrew S. Florea Marvin P. Fried* Paul Louis Friedlander Ellen M. Friedman Rick A. Friedman Henry Frierson Patrick Froehlich Nabil Fuleihan Thomas J. Gal Ian Ganly Bruce J. Gantz* Noel Garabedian C. Gaelyn Garrett Soha Ghossaini Ziv Gil Daniel Ginat Lyon L. Gleich George S. Goding Joel Goebel Whitney Goldner Nira Goldstein Mitchell Gore Christine G. Gourin Alberto Grammatica Stacey Gray John Herman Greinwald Neil Gross Kenneth Grundfast Christian Guilleminault Arsheed Hakeem Earl H. Harley Christopher J. Hartnick George Hashisaki David Haynes Kevin C. Hazen Keith S. Heller Peter Hilger Henry Hoffman F. Christopher Holsinger Benjamin Huang Julia C. Iezzoni Brandon Isaacson Lisa Ishii Stacey Ishman Robert Jackler Ian N. Jacobs Rajan Jain Mark J. Jameson* Herman Jenkins Anita Jeyakumar Vickie Jo Carl Johnson Benjamin Judson Shin-ichi Kanemaru Kian Karimi Lucy Karnell David M. Kaylie Robert Kellman Margaret Kenna Bradley W. Kesser* Eric Kezirian Ayesha Khalid Ana Kim Michael Kim Claudia Kirsch Daniel Kirse Bernadette Koch Wayne Koch Peter Koltai Christina Kong Paul Krakovitz Dennis Kraus Piotr Kurnatowski David Kutler Joe Kutz Stephen Y. Lai Anil K. Lalwani* David Larson Daniel Lee Robin D. Legallo Benjamin Leiss Marci M. Lesperance* James S. Lewis Greg Licameli Judith E. C. Lieu Derrick T. Lin Todd Loehrl Brenda Lonsbury-Martin M. Beatriz Lopes Robert Lorenz Lawrence Lustig William M. Lydiatt*","PeriodicalId":8285,"journal":{"name":"Archives of otolaryngology--head & neck surgery","volume":"110 1","pages":"1108-1109"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87669327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Predictors of pain among patients with head and neck cancer. 头颈癌患者疼痛的预测因素。
Pub Date : 2012-12-01 DOI: 10.1001/jamaoto.2013.853
Andrew G Shuman, Jeffrey E Terrell, Emily Light, Gregory T Wolf, Carol R Bradford, Douglas Chepeha, Yunyun Jiang, Scott McLean, Tamer A Ghanem, Sonia A Duffy

OBJECTIVE To determine predictors of pain 1 year after the diagnosis of head and neck cancer. DESIGN Prospective, multisite cohort study. SETTING Three academically affiliated medical centers. PATIENTS The study population comprised 374 previously untreated patients with carcinoma of the upper aerodigestive tract. MAIN OUTCOME MEASURES Participants were surveyed before treatment and 1 year thereafter. Multivariate analyses were conducted to determine predictors of the 36-Item Short-Form Instrument (SF-36) bodily pain score 1 year after diagnosis. RESULTS The mean SF-36 bodily pain score at 1 year was 65, compared with 61 at the time of diagnosis (P = .004), and 75, the population norm (lower scores indicate worse pain). Variables independently associated with pain included pretreatment pain score (P < .001), less education (P = .02), neck dissection (P = .001), feeding tube (P = .05), xerostomia (P < .001), depressive symptoms (P < .001), taking more pain medication (P < .001), less physical activity (P = .02), and poor sleep quality (P = .006). The association between head and neck cancer pain and current smoking and problem drinking did not reach significance (P = .07 and P = .08, respectively). CONCLUSIONS Aggressive pain management may be indicated for patients with head and neck cancer who undergo neck dissections, complain of xerostomia, require feeding tubes, and have medical comorbidities. Treatment of modifiable risk factors such as depression, poor sleep quality, tobacco use, and alcohol abuse may also reduce pain and improve quality of life among patients with head and neck cancer.

目的探讨头颈癌诊断后1年疼痛的预测因素。前瞻性、多地点队列研究。三个学术附属医疗中心。研究人群包括374名先前未经治疗的上气消化道癌患者。主要观察指标:参与者在治疗前和治疗后1年接受调查。进行多变量分析以确定诊断后1年36项简易量表(SF-36)身体疼痛评分的预测因子。结果1年时SF-36身体疼痛平均评分为65分,而诊断时为61分(P = 0.004),人群常值为75分(得分越低疼痛越严重)。与疼痛独立相关的变量包括预处理疼痛评分(P <.001),教育程度低(P = 0.02),颈部解剖(P = 0.001),饲管(P = 0.05),口干(P <.001)、抑郁症状(P <.001),服用更多止痛药(P <.001)、体力活动较少(P = .02)和睡眠质量差(P = .006)。头颈癌疼痛与当前吸烟和问题饮酒之间的关系没有达到显著性(P = 0.07和P = 0.08)。结论:头颈癌患者行颈部解剖,主诉口干,需要喂食管,并有医学合并症,积极的疼痛管理可能适用。治疗可改变的危险因素,如抑郁、睡眠质量差、吸烟和酗酒,也可能减轻头颈癌患者的疼痛,提高生活质量。
{"title":"Predictors of pain among patients with head and neck cancer.","authors":"Andrew G Shuman,&nbsp;Jeffrey E Terrell,&nbsp;Emily Light,&nbsp;Gregory T Wolf,&nbsp;Carol R Bradford,&nbsp;Douglas Chepeha,&nbsp;Yunyun Jiang,&nbsp;Scott McLean,&nbsp;Tamer A Ghanem,&nbsp;Sonia A Duffy","doi":"10.1001/jamaoto.2013.853","DOIUrl":"https://doi.org/10.1001/jamaoto.2013.853","url":null,"abstract":"<p><p>OBJECTIVE To determine predictors of pain 1 year after the diagnosis of head and neck cancer. DESIGN Prospective, multisite cohort study. SETTING Three academically affiliated medical centers. PATIENTS The study population comprised 374 previously untreated patients with carcinoma of the upper aerodigestive tract. MAIN OUTCOME MEASURES Participants were surveyed before treatment and 1 year thereafter. Multivariate analyses were conducted to determine predictors of the 36-Item Short-Form Instrument (SF-36) bodily pain score 1 year after diagnosis. RESULTS The mean SF-36 bodily pain score at 1 year was 65, compared with 61 at the time of diagnosis (P = .004), and 75, the population norm (lower scores indicate worse pain). Variables independently associated with pain included pretreatment pain score (P &lt; .001), less education (P = .02), neck dissection (P = .001), feeding tube (P = .05), xerostomia (P &lt; .001), depressive symptoms (P &lt; .001), taking more pain medication (P &lt; .001), less physical activity (P = .02), and poor sleep quality (P = .006). The association between head and neck cancer pain and current smoking and problem drinking did not reach significance (P = .07 and P = .08, respectively). CONCLUSIONS Aggressive pain management may be indicated for patients with head and neck cancer who undergo neck dissections, complain of xerostomia, require feeding tubes, and have medical comorbidities. Treatment of modifiable risk factors such as depression, poor sleep quality, tobacco use, and alcohol abuse may also reduce pain and improve quality of life among patients with head and neck cancer.</p>","PeriodicalId":8285,"journal":{"name":"Archives of otolaryngology--head & neck surgery","volume":"138 12","pages":"1147-54"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/jamaoto.2013.853","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31059634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 55
The effects of balloon dilation laryngoplasty in children with congenital heart disease. 球囊扩张喉成形术治疗儿童先天性心脏病的疗效观察。
Pub Date : 2012-12-01 DOI: 10.1001/jamaoto.2013.676
William O Collins, Nader Kalantar, Hillary B Rohrs, Rodrigo C Silva

Objective: To determine the utility of performing balloon dilation laryngoplasty of subglottic stenosis (SGS) in children with underlying congenital heart disease (CHD).

Design: Retrospective study.

Setting: Tertiary care academic health center.

Patients: Children with an underlying diagnosis of CHD who subsequently underwent balloon dilation laryngoplasty for SGS from January 1, 2006, through December 31, 2011.

Main outcome measures: Clinical improvement and avoidance of tracheotomy.

Results: We identified 16 children who had a diagnosis of CHD and underwent direct laryngoscopy and bronchoscopy. Five patients (3 girls and 2 boys) underwent a total of 11 balloon dilations for SGS. Their ages at initial dilation ranged from 1 to 4 months. All 5 patients had grade III SGS. Only 1 patient required a salvage tracheotomy for a thick glottic web and associated SGS after her first balloon dilation failed to improve airway patency. The remaining 4 patients have had long-term success in avoiding tracheotomy with symptomatic improvement.

Conclusions: Balloon dilation represents a valuable treatment option in patients with CHD and SGS in whom a tracheostomy should be avoided.

目的:探讨球囊扩张喉成形术治疗先天性心脏病(CHD)患儿声门下狭窄的疗效。设计:回顾性研究。环境:三级保健学术保健中心。患者:2006年1月1日至2011年12月31日期间,诊断为冠心病的儿童随后接受了SGS气囊扩张喉成形术。主要观察指标:临床改善,避免气管切开术。结果:我们确定了16名诊断为冠心病的儿童,并接受了直接喉镜检查和支气管镜检查。5例患者(3名女孩和2名男孩)共接受了11次球囊扩张治疗。初次扩张时的年龄为1 ~ 4个月。5例患者均为III级SGS。只有1例患者在第一次球囊扩张未能改善气道通畅后,需要进行补救性气管切开术治疗厚声门网和相关的SGS。其余4例患者长期成功避免了气管切开术,症状有所改善。结论:球囊扩张是避免气管切开术的冠心病和SGS患者的一种有价值的治疗选择。
{"title":"The effects of balloon dilation laryngoplasty in children with congenital heart disease.","authors":"William O Collins,&nbsp;Nader Kalantar,&nbsp;Hillary B Rohrs,&nbsp;Rodrigo C Silva","doi":"10.1001/jamaoto.2013.676","DOIUrl":"https://doi.org/10.1001/jamaoto.2013.676","url":null,"abstract":"<p><strong>Objective: </strong>To determine the utility of performing balloon dilation laryngoplasty of subglottic stenosis (SGS) in children with underlying congenital heart disease (CHD).</p><p><strong>Design: </strong>Retrospective study.</p><p><strong>Setting: </strong>Tertiary care academic health center.</p><p><strong>Patients: </strong>Children with an underlying diagnosis of CHD who subsequently underwent balloon dilation laryngoplasty for SGS from January 1, 2006, through December 31, 2011.</p><p><strong>Main outcome measures: </strong>Clinical improvement and avoidance of tracheotomy.</p><p><strong>Results: </strong>We identified 16 children who had a diagnosis of CHD and underwent direct laryngoscopy and bronchoscopy. Five patients (3 girls and 2 boys) underwent a total of 11 balloon dilations for SGS. Their ages at initial dilation ranged from 1 to 4 months. All 5 patients had grade III SGS. Only 1 patient required a salvage tracheotomy for a thick glottic web and associated SGS after her first balloon dilation failed to improve airway patency. The remaining 4 patients have had long-term success in avoiding tracheotomy with symptomatic improvement.</p><p><strong>Conclusions: </strong>Balloon dilation represents a valuable treatment option in patients with CHD and SGS in whom a tracheostomy should be avoided.</p>","PeriodicalId":8285,"journal":{"name":"Archives of otolaryngology--head & neck surgery","volume":"138 12","pages":"1136-40"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/jamaoto.2013.676","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31128710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
期刊
Archives of otolaryngology--head & neck surgery
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1