Pub Date : 2012-10-01DOI: 10.1001/archophthalmol.2012.2250
Eleonora M Lad, Jason R Karamchandani, Deborah M Alcorn, Darius M Moshfeghi, Peter R Egbert
Report of a Case. Our patient was born at term with buphthalmos and proptosis of her right eye, accompanied by corneal clouding and increased tearing. She was subsequently noted to have right sphenoid wing dysplasia, multiple cutaneous plexiform neuromas of the right eyelids and face (fifth nerve distribution), right hemispheric dysplastic polymicrogyria, and a seizure disorder. She was diagnosed as having NF1. The left eye was within normal limits. The patient received a Baerveldt glaucoma drainage implant at age 5.5 months. At age 8 months, a dilated fundus examination revealed temporal retinal whitening and posterior retinal hemorrhages, which were initially attributed to a retinal vein occlusion. Four months later, the patient was diagnosed clinically as having a CHRRPE (Figure 1). Enlargement of the retinal tumor was noted over the following 8 months, accompanied by the development of a vitreous hemorrhage, tractional retinal detachment, and proliferative vitreoretinopathy. At age 20 months, the right eye was enucleated owing to it being blind and painful with a fixed pupil and corneal haze. Postoperatively, she was more comfortable, no longer photophobic, and without tearing. Gross pathologic examination revealed a buphthalmic eye with a Baerveldt glaucoma drainage implant on the superonasal sclera. On oblique sectioning, the cornea was clear but thinned. The anterior chamber was filled with a tan, milky fluid. The pupil was widely dilated and the iridocorneal angle was closed by peripheral anterior synechiae. The lens and uveal tract were unremarkable. There was a funnel-shaped retinal detachment. Microscopic examination revealed an absent Bowman layer, which was replaced by an area of thin cellular fibrosis. A membrane composed of corneal endothelial cells was present over the surface of the severely contracted iris and ciliary body. The lens showed cataract formation with anterior calcific degeneration and posterior migration of the lens epithelium. The uvea was thickened by a diffuse neurofibroma typical for eyes involved with NF1. The predominant spindle cells within the neurofibroma reacted positively with S-100 protein and microtubule-associated protein 2 but were negative for glial fibrillary acidic protein, CD56 (neural cell adhesion molecule—a marker of neurons, astrocytes, and nonmyelinating Schwann cells), neurofilament, and Ki-67. Scattered clusters of larger neuronal cells with comparatively more abundant cytoplasm and large round nuclei with prominent nucleoli were also present and were positive for synaptophysin, microtubuleassociated protein 2, and neurofilament (Figure 2). The detached retina was displaced anteriorly and centrally by a fibrovascular proliferation in the vitreous. A retinal tumor replaced a broad area of the inner retina
{"title":"Retinal glioneuronal hamartoma in neurofibromatosis type 1.","authors":"Eleonora M Lad, Jason R Karamchandani, Deborah M Alcorn, Darius M Moshfeghi, Peter R Egbert","doi":"10.1001/archophthalmol.2012.2250","DOIUrl":"https://doi.org/10.1001/archophthalmol.2012.2250","url":null,"abstract":"Report of a Case. Our patient was born at term with buphthalmos and proptosis of her right eye, accompanied by corneal clouding and increased tearing. She was subsequently noted to have right sphenoid wing dysplasia, multiple cutaneous plexiform neuromas of the right eyelids and face (fifth nerve distribution), right hemispheric dysplastic polymicrogyria, and a seizure disorder. She was diagnosed as having NF1. The left eye was within normal limits. The patient received a Baerveldt glaucoma drainage implant at age 5.5 months. At age 8 months, a dilated fundus examination revealed temporal retinal whitening and posterior retinal hemorrhages, which were initially attributed to a retinal vein occlusion. Four months later, the patient was diagnosed clinically as having a CHRRPE (Figure 1). Enlargement of the retinal tumor was noted over the following 8 months, accompanied by the development of a vitreous hemorrhage, tractional retinal detachment, and proliferative vitreoretinopathy. At age 20 months, the right eye was enucleated owing to it being blind and painful with a fixed pupil and corneal haze. Postoperatively, she was more comfortable, no longer photophobic, and without tearing. Gross pathologic examination revealed a buphthalmic eye with a Baerveldt glaucoma drainage implant on the superonasal sclera. On oblique sectioning, the cornea was clear but thinned. The anterior chamber was filled with a tan, milky fluid. The pupil was widely dilated and the iridocorneal angle was closed by peripheral anterior synechiae. The lens and uveal tract were unremarkable. There was a funnel-shaped retinal detachment. Microscopic examination revealed an absent Bowman layer, which was replaced by an area of thin cellular fibrosis. A membrane composed of corneal endothelial cells was present over the surface of the severely contracted iris and ciliary body. The lens showed cataract formation with anterior calcific degeneration and posterior migration of the lens epithelium. The uvea was thickened by a diffuse neurofibroma typical for eyes involved with NF1. The predominant spindle cells within the neurofibroma reacted positively with S-100 protein and microtubule-associated protein 2 but were negative for glial fibrillary acidic protein, CD56 (neural cell adhesion molecule—a marker of neurons, astrocytes, and nonmyelinating Schwann cells), neurofilament, and Ki-67. Scattered clusters of larger neuronal cells with comparatively more abundant cytoplasm and large round nuclei with prominent nucleoli were also present and were positive for synaptophysin, microtubuleassociated protein 2, and neurofilament (Figure 2). The detached retina was displaced anteriorly and centrally by a fibrovascular proliferation in the vitreous. A retinal tumor replaced a broad area of the inner retina","PeriodicalId":8303,"journal":{"name":"Archives of ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archophthalmol.2012.2250","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30960642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-10-01DOI: 10.1001/archophthalmol.2012.1389
Zia Chaudhuri, Joseph L Demer
Objective: To propose medial rectus (MR) recession to be equally as effective as lateral rectus (LR) resection, which has heretofore been the preferred treatment for divergence paralysis esotropia (DPE).
Methods: We examined a 17-year surgical experience comparing LR resection with MR recession in adults with DPE, defined as symptomatic distance esotropia (ET) at least double the asymptomatic ET of 10 or less prism diopters() at near.
Results: Twenty-four patients with DPE underwent surgery. Six patients underwent bilateral LR resection and 2 underwent unilateral LR resection (group L), while 13 underwent bilateral MR recession and 3 underwent unilateral MR recession,with the target angle double the distance ET (group M). One of 8 patients in group L and 15 of 16 patients in group M underwent intra operative adjustable surgery under topical anesthesia. Mean (SD) preoperative central gaze ET measured 15.0 (7.7) Δ at distance and 4.1 (3.4) Δ at near in group L, but 10.4 (6.8) Δ at distance and 0.6 (1.7) Δ at near in group M (P=.15; distance, 0.003, near). Postoperatively, no patient in either group had symptomatic diplopia or convergence insufficiency in follow-up from 8.5 to 40 months. Twice the usual surgical dose of MR recession per prism diopter was required to achieve correction of the distance deviation in DPE as compared with that recommended for ET generally and also for LR resection in the same condition.
Conclusions: Recession of the MR provides binocular single vision in DPE without convergence insufficiency at near, and it is convenient for intraoperative adjustment under topical anesthesia.
{"title":"Medial rectus recession is as effective as lateral rectus resection in divergence paralysis esotropia.","authors":"Zia Chaudhuri, Joseph L Demer","doi":"10.1001/archophthalmol.2012.1389","DOIUrl":"https://doi.org/10.1001/archophthalmol.2012.1389","url":null,"abstract":"<p><strong>Objective: </strong>To propose medial rectus (MR) recession to be equally as effective as lateral rectus (LR) resection, which has heretofore been the preferred treatment for divergence paralysis esotropia (DPE).</p><p><strong>Methods: </strong>We examined a 17-year surgical experience comparing LR resection with MR recession in adults with DPE, defined as symptomatic distance esotropia (ET) at least double the asymptomatic ET of 10 or less prism diopters() at near.</p><p><strong>Results: </strong>Twenty-four patients with DPE underwent surgery. Six patients underwent bilateral LR resection and 2 underwent unilateral LR resection (group L), while 13 underwent bilateral MR recession and 3 underwent unilateral MR recession,with the target angle double the distance ET (group M). One of 8 patients in group L and 15 of 16 patients in group M underwent intra operative adjustable surgery under topical anesthesia. Mean (SD) preoperative central gaze ET measured 15.0 (7.7) Δ at distance and 4.1 (3.4) Δ at near in group L, but 10.4 (6.8) Δ at distance and 0.6 (1.7) Δ at near in group M (P=.15; distance, 0.003, near). Postoperatively, no patient in either group had symptomatic diplopia or convergence insufficiency in follow-up from 8.5 to 40 months. Twice the usual surgical dose of MR recession per prism diopter was required to achieve correction of the distance deviation in DPE as compared with that recommended for ET generally and also for LR resection in the same condition.</p><p><strong>Conclusions: </strong>Recession of the MR provides binocular single vision in DPE without convergence insufficiency at near, and it is convenient for intraoperative adjustment under topical anesthesia.</p>","PeriodicalId":8303,"journal":{"name":"Archives of ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archophthalmol.2012.1389","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30682539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-10-01DOI: 10.1001/archophthalmol.2012.1837
Shan C Lin, Guofu Huang
{"title":"Why was there no correlation between anterior chamber depth and intraocular pressure change after phacoemulsification in patients with narrow angles?-Reply.","authors":"Shan C Lin, Guofu Huang","doi":"10.1001/archophthalmol.2012.1837","DOIUrl":"https://doi.org/10.1001/archophthalmol.2012.1837","url":null,"abstract":"","PeriodicalId":8303,"journal":{"name":"Archives of ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archophthalmol.2012.1837","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31495274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-10-01DOI: 10.1001/archophthalmol.2012.2290
Rahat Husain, Tin Aung
{"title":"Effect of cataract surgery and 5-Fluorouracil on trabeculectomy function-reply.","authors":"Rahat Husain, Tin Aung","doi":"10.1001/archophthalmol.2012.2290","DOIUrl":"https://doi.org/10.1001/archophthalmol.2012.2290","url":null,"abstract":"","PeriodicalId":8303,"journal":{"name":"Archives of ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archophthalmol.2012.2290","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31495285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-10-01DOI: 10.1001/archophthalmol.2012.2226
Jason Cheng, K Sheng Lim
{"title":"Why was there no correlation between anterior chamber depth and intraocular pressure change after phacoemulsification in patients with narrow angles?","authors":"Jason Cheng, K Sheng Lim","doi":"10.1001/archophthalmol.2012.2226","DOIUrl":"https://doi.org/10.1001/archophthalmol.2012.2226","url":null,"abstract":"","PeriodicalId":8303,"journal":{"name":"Archives of ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archophthalmol.2012.2226","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30959051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-10-01DOI: 10.1001/archophthalmol.2012.1988
David L Parver, Robert J Dreher, Sahar Kohanim, Paul Zimmerman, Geoffrey Garrett, Laxmi Devisetty, Louis R Pasquale
{"title":"Ocular injury after laser hair reduction treatment to the eyebrow.","authors":"David L Parver, Robert J Dreher, Sahar Kohanim, Paul Zimmerman, Geoffrey Garrett, Laxmi Devisetty, Louis R Pasquale","doi":"10.1001/archophthalmol.2012.1988","DOIUrl":"https://doi.org/10.1001/archophthalmol.2012.1988","url":null,"abstract":"","PeriodicalId":8303,"journal":{"name":"Archives of ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archophthalmol.2012.1988","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30960640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-10-01DOI: 10.1001/archophthalmol.2012.845
Jennifer Renz, Jordana G Fein, Robin Vora, Harold Woodcome, Elias Reichel, Jay Duker
1. Yannuzzi LA. Central serous chorioretinopathy. In: Yannuzzi LA, ed. Laser Photocoagulation of the Macula. Philadelphia, PA: JB Lippincott Co; 1989:4. 2. Imamura Y, Fujiwara T, Margolis R, Spaide RF. Enhanced depth imaging optical coherence tomography of the choroid in central serous chorioretinopathy. Retina. 2009;29(10):1469-1473. 3. Fujiwara T, Imamura Y, Margolis R, Slakter JS, Spaide RF. Enhanced depth imaging optical coherence tomography of the choroid in highly myopic eyes. Am J Ophthalmol. 2009;148(3):445-450. 4. Margolis R, Spaide RF. A pilot study of enhanced depth imaging optical coherence tomography of the choroid in normal eyes. Am J Ophthalmol. 2009; 147(5):811-815.
{"title":"Unilateral retinal pigment epithelium dysgenesis may be a bilateral disease.","authors":"Jennifer Renz, Jordana G Fein, Robin Vora, Harold Woodcome, Elias Reichel, Jay Duker","doi":"10.1001/archophthalmol.2012.845","DOIUrl":"https://doi.org/10.1001/archophthalmol.2012.845","url":null,"abstract":"1. Yannuzzi LA. Central serous chorioretinopathy. In: Yannuzzi LA, ed. Laser Photocoagulation of the Macula. Philadelphia, PA: JB Lippincott Co; 1989:4. 2. Imamura Y, Fujiwara T, Margolis R, Spaide RF. Enhanced depth imaging optical coherence tomography of the choroid in central serous chorioretinopathy. Retina. 2009;29(10):1469-1473. 3. Fujiwara T, Imamura Y, Margolis R, Slakter JS, Spaide RF. Enhanced depth imaging optical coherence tomography of the choroid in highly myopic eyes. Am J Ophthalmol. 2009;148(3):445-450. 4. Margolis R, Spaide RF. A pilot study of enhanced depth imaging optical coherence tomography of the choroid in normal eyes. Am J Ophthalmol. 2009; 147(5):811-815.","PeriodicalId":8303,"journal":{"name":"Archives of ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archophthalmol.2012.845","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30960645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-10-01DOI: 10.1001/archophthalmol.2012.2462
Ingrid U Scott
{"title":"Management of macular edema associated with retinal vein occlusion.","authors":"Ingrid U Scott","doi":"10.1001/archophthalmol.2012.2462","DOIUrl":"https://doi.org/10.1001/archophthalmol.2012.2462","url":null,"abstract":"","PeriodicalId":8303,"journal":{"name":"Archives of ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archophthalmol.2012.2462","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30960634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-10-01DOI: 10.1001/archophthalmol.2012.1459
Neda Nikpoor, Amir L Butt, Alan R Hromas, Donald U Stone
{"title":"Effect of the physician quality reporting initiative on ophthalmologists' documentation of practice patterns.","authors":"Neda Nikpoor, Amir L Butt, Alan R Hromas, Donald U Stone","doi":"10.1001/archophthalmol.2012.1459","DOIUrl":"https://doi.org/10.1001/archophthalmol.2012.1459","url":null,"abstract":"","PeriodicalId":8303,"journal":{"name":"Archives of ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archophthalmol.2012.1459","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30959050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-10-01DOI: 10.1001/archophthalmol.2012.2217
Saurabh Kamal
{"title":"Increased levator muscle function by supramaximal resection in patients with blepharophimosis-ptosis-epicanthus inversus syndrome.","authors":"Saurabh Kamal","doi":"10.1001/archophthalmol.2012.2217","DOIUrl":"https://doi.org/10.1001/archophthalmol.2012.2217","url":null,"abstract":"","PeriodicalId":8303,"journal":{"name":"Archives of ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archophthalmol.2012.2217","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30959055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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