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Surgical removal of an atypical macular epiretinal membrane in neurofibromatosis type 2: clinicopathologic correlation and visual outcome. 2型神经纤维瘤病非典型黄斑视网膜上膜的手术切除:临床病理相关性和视觉结果。
Pub Date : 2012-10-01 DOI: 10.1001/archophthalmol.2012.2305
Dennis P Han, Melody Chin, Kenneth B Simons, Daniel M Albert
University, Durham, North Carolina (Dr Lad); Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada (Dr Karamchandani); and Department of Pediatrics, Lucile Packard Children’s Hospital at Stanford (Dr Alcorn) and Eye Institute at Stanford, Stanford University School of Medicine (Drs Alcorn, Moshfeghi, and Egbert), Stanford, California. Correspondence: Dr Egbert, Eye Institute at Stanford, 2452 Watson Ct, MC 5353, Palo Alto, CA 94303 (egbert @stanford.edu). Author Contributions: Drs Lad and Karamchandani contributed equally to this work. Financial Disclosure: None reported.
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引用次数: 6
Retinal necrosis following varicella-zoster vaccination. 水痘-带状疱疹疫苗接种后视网膜坏死。
Pub Date : 2012-10-01 DOI: 10.1001/archophthalmol.2012.2255
John A Gonzales, Ashleigh L Levison, Jay M Stewart, Nisha R Acharya, Todd P Margolis
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引用次数: 23
Monteath's translation of Weller: an underappreciated trove of ophthalmology lexicon. 蒙泰斯翻译的韦勒:一个被低估的眼科词汇宝库。
Pub Date : 2012-10-01 DOI: 10.1001/archophthalmol.2012.2084
Christopher T Leffler, Jessica Randolph, Russell Stackhouse, Byrd Davenport, Karli Spetzler
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引用次数: 4
Characteristics and visual outcome of patients with retinal vasculitis. 视网膜血管炎患者的特点及视力结果。
Pub Date : 2012-10-01 DOI: 10.1001/archophthalmol.2012.1596
Jennifer H Ku, Amro Ali, Eric B Suhler, Dongseok Choi, James T Rosenbaum

Objective: To examine the characteristics and visual outcome in 207 patients with retinal vasculitis.

Methods: Demographic and visual outcome data were collected retrospectively from the ophthalmologic records of 207 cases (321 affected eyes). Descriptive analysis was performed on all cases and visual outcome analysis was performed for the 114 cases with visual acuity recorded at 2 or more visits. The Kaplan-Meier method and Cox regression were used to examine visual outcome and predictors for prognosis.

Results: Patients in our series had a roughly even distribution of sex, were predominantly non-Hispanic white (77.8%), and had bilateral disease (75.7%). The annualized mean visual acuity change for the 203 eyes (114 patients) with some follow-up was 0.01 logMAR unit per year. Although 75 eyes (36.9%) had 20/25 or better visual acuity at baseline, 33.6% of the remaining eyes experienced visual acuity improvement of at least 2 lines on the Snellen chart during follow-up and some continued to improve more than 9 years after the initial evaluation. Cox multivariate analysis demonstrated that patients who were nonwhite, had worse visual acuity at baseline, or who had an ocular infection were more likely to experience improvement by this definition.

Conclusions: We believe that this is the first US case series to investigate visual outcome in patients with this diagnosis. Although many patients in our series worsened despite therapy, a subset experienced substantial improvement.

目的:探讨207例视网膜血管炎的特点及视力结果。方法:回顾性收集207例(321只眼)眼科病例的人口学和视力资料。对所有病例进行描述性分析,对114例就诊2次及以上视力记录的病例进行视力结果分析。使用Kaplan-Meier法和Cox回归检查视觉结果和预后预测因素。结果:本系列患者的性别分布大致均匀,主要是非西班牙裔白人(77.8%),双侧疾病(75.7%)。203只眼(114例)随访后的年平均视力变化为0.01 logMAR单位/年。虽然75只眼(36.9%)在基线时的视力为20/25或更好,但在随访期间,其余33.6%的眼的视力在Snellen图表上至少改善了2条线,有些眼在初始评估后持续改善超过9年。Cox多变量分析表明,非白人、基线视力较差或有眼部感染的患者更有可能根据这一定义获得改善。结论:我们认为这是美国第一个研究这种诊断患者视力结果的病例系列。尽管在我们的研究中,许多患者在接受治疗后病情恶化,但有一部分患者得到了实质性的改善。
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引用次数: 27
Myopic schisis with scrolled posterior hyaloid. 近视眼裂伴后玻璃体滚动。
Pub Date : 2012-10-01 DOI: 10.1001/archophthalmol.2012.1500
Adam Alexander Reisner, Robin A Vora, Darin R Goldman, Jay S Duker
ziness or vertigo, possibly involving vision impairment. A 1917 encyclopedia entry stated that English surgeon and former Beer student James Wardrop coined the term keratitis in an 1808 text. This claim has become conventional wisdom. In fact, Wardrop spoke simply of inflammation or ulcer of the cornea. We could not find the terms keratitis or ceratitis in Wardrop’s works (eReferences 3-18). To date, the first documented use of the term keratitis is by Weller and, in English, by Monteath. Monteath’s English translation became his bestknown work and has left an important lexical legacy.
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引用次数: 1
Cell-based therapy for glaucomatous optic nerve degeneration. 青光眼视神经变性的细胞治疗。
Pub Date : 2012-10-01 DOI: 10.1001/2012.jamaophthalmol.252
Marco Zarbin
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引用次数: 0
Quinupristin/dalfopristin in vancomycin-resistant Staphylococcus aureus endophthalmitis. 奎奴普汀/达福普汀治疗耐万古霉素金黄色葡萄球菌眼内炎。
Pub Date : 2012-10-01 DOI: 10.1001/archophthalmol.2012.1504
Edward M Stroh
Postoperative bacterial endophthalmitis is the most dreaded complication of any eye surgery. Once infection is suspected, prompt treatment by vitreous tap and biopsy or by vitrectomy and injection of intravitreal antibiotics is instituted prior to identifying the specific bacteria and its antibiotic sensitivities. Of the 70% of cases that were culture positive in the Endophthalmitis Vitrectomy Study (EVS), 94% were grampositive organisms that were all sensitive to vancomycin. The recent Antibiotic Resistance Monitoring in Ocular micRorganisms 2009 study reported that 39% of Staphylococcus aureus isolates were resistant to methicillin, but all were still sensitive to vancomycin. Several recent cases of endophthalmitis due to vancomycin-resistant S aureus and Enterococcus have also been reported. Of the few antibiotics effective against vancomycin-resistant bacteria, only intravitreal quinupristin/dalfopristin has been reported previously in a single human eye. In the current series, 2 additional cases are reported with successful treatment of vancomycin-resistant S aureus endophthalmitis with intravitreal quinupristin/dalfopristin.
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引用次数: 11
Transformation of optic disc melanocytoma into melanoma over 33 years. 视盘黑色素细胞瘤向黑色素瘤的转变超过33年。
Pub Date : 2012-10-01 DOI: 10.1001/archophthalmol.2012.740
Shripaad Y Shukla, Jerry A Shields, Ralph C Eagle, Carol L Shields
sure was 8 mm Hg OU. Biomicroscopic examination revealed small, nongranulomatous keratic precipitates, 1 anterior chamber cell and flare, 1 to 2 vitreous cells and 1 haze, and multiple hypopigmented punctate lesions in the foveae in both eyes. These lesions demonstrated early staining on fluorescein angiography (Figure, A and B) and nodular increased reflectivity at the level of the retinal pigment epithelium on optical coherence tomography (Figure, E). Color fundus photographs were not available. After confirming negative results on chest radiography and syphilis serology, we initiated oral prednisone, 60 mg/d with an extended taper. At each successive visit, her visual acuity and symptoms improved. After completion of a 2-month prednisone taper, her visual acuity was back to baseline (20/40 OU), limited only by preexisting cataracts. The punctate lesions had nearly completely resolved on both examination and ancillary testing (Figure, C, D, and F).
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引用次数: 16
Florid arteritis confined to a single branch of the superficial temporal artery. 局限于颞浅动脉单一分支的动脉炎。
Pub Date : 2012-10-01 DOI: 10.1001/archophthalmol.2012.1204
Sung-Eun E Kyung, Michael K Yoon, J Brooks Crawford, Jonathan C Horton
for the integrity of the data and the accuracy of the data analysis. Financial Disclosure: None reported. Funding/Support: This work was supported by Eye Tu- mor Research Foundation, Philadelphia, Pennsylvania (Drs J. A. Shields and C. L. Shields). Role of the Sponsor: The sponsor had no role in the de- sign and conduct of the study; in the collection, analy- sis, and interpretation of the data; or in the preparation, review, or approval of the manuscript. 1. Zimmerman LE, Garron LK. Melanocytoma of the optic disc. Int Ophthalmol Clin. 1962;2:431-440. 2. Apple DJ, Craythorn JM, Reidy JJ, Steinmetz RL, Brady SE, Bohart WA. Ma- lignant transformation of an optic nerve melanocytoma. Can J Ophthalmol. 3. Shields JA, Shields CL, Eagle RC Jr, Lieb WE, Stern S. Malignant melanoma associated with melanocytoma of the optic disc. Ophthalmology. 1990;97 4. Meyer D, Ge J, Blinder KJ, Sinard J, Xu S. Malignant transformation of an op- tic disk melanocytoma. Am J Ophthalmol. 1999;127(6):710-714. 5. Shields JA, Demirci H, Mashayekhi A, Shields CL. Melanocytoma of optic disc in 115 cases: the 2004 Samuel Johnson Memorial Lecture, part 1. Ophthalmology. 6. Shields JA, Demirci H, Mashayekhi A, Eagle RC Jr, Shields CL. Melanocy- toma of the optic disk: a review. Surv Ophthalmol. 2006;51(2):93-104. 7. Horgan N, Shields CL, Swanson L, et al. Altered chromosome expression of uveal melanoma in the setting of melanocytosis. Acta Ophthalmol. 2009;87 branches of the superficial temporal artery. In fact, sur- geons usually fail to specify which branch was biopsied when they submit specimens, and no histological data exist regarding which branch is more likely to demon- strate arteritis. Recently, it was suggested that the parietal branch, rather than the frontal branch, should be biopsied in pa- tients with suspected temporal arteritis. 3 This approach eliminates the remote risk of facial nerve injury and usu- ally hides the scar behind the hairline. However, this rec- ommendation was predicated on the assumption that the prevalence of arteritis is equal in the parietal and frontal branches. We now show that selective involvement of a single vessel branch can occur in temporal arteritis. Magnetic resonance imaging has been used to com- pare the involvement of the parietal vs frontal branch in temporal arteritis. In 21 patients with suspected giant cell arteritis, involvement was rated by noting the amount of mural thickening and gadolinium enhancement of the vessel and perivascular tissue. 4 On the left side, abnor- malities were present in 14 patients in the frontal branch and in 6 patients in the parietal branch. On the right side, A Florid Arteritis Confined to a Single Branch of the Superficial Temporal Artery B iopsy of the superficial temporal artery provides vital confirmation of the diagnosis of giant cell arteritis. The vessel splits into 2 main branches: frontal and parietal. It is unknown which branch is most likely to yield a positive biopsy finding or, indeed,
{"title":"Florid arteritis confined to a single branch of the superficial temporal artery.","authors":"Sung-Eun E Kyung,&nbsp;Michael K Yoon,&nbsp;J Brooks Crawford,&nbsp;Jonathan C Horton","doi":"10.1001/archophthalmol.2012.1204","DOIUrl":"https://doi.org/10.1001/archophthalmol.2012.1204","url":null,"abstract":"for the integrity of the data and the accuracy of the data analysis. Financial Disclosure: None reported. Funding/Support: This work was supported by Eye Tu- mor Research Foundation, Philadelphia, Pennsylvania (Drs J. A. Shields and C. L. Shields). Role of the Sponsor: The sponsor had no role in the de- sign and conduct of the study; in the collection, analy- sis, and interpretation of the data; or in the preparation, review, or approval of the manuscript. 1. Zimmerman LE, Garron LK. Melanocytoma of the optic disc. Int Ophthalmol Clin. 1962;2:431-440. 2. Apple DJ, Craythorn JM, Reidy JJ, Steinmetz RL, Brady SE, Bohart WA. Ma- lignant transformation of an optic nerve melanocytoma. Can J Ophthalmol. 3. Shields JA, Shields CL, Eagle RC Jr, Lieb WE, Stern S. Malignant melanoma associated with melanocytoma of the optic disc. Ophthalmology. 1990;97 4. Meyer D, Ge J, Blinder KJ, Sinard J, Xu S. Malignant transformation of an op- tic disk melanocytoma. Am J Ophthalmol. 1999;127(6):710-714. 5. Shields JA, Demirci H, Mashayekhi A, Shields CL. Melanocytoma of optic disc in 115 cases: the 2004 Samuel Johnson Memorial Lecture, part 1. Ophthalmology. 6. Shields JA, Demirci H, Mashayekhi A, Eagle RC Jr, Shields CL. Melanocy- toma of the optic disk: a review. Surv Ophthalmol. 2006;51(2):93-104. 7. Horgan N, Shields CL, Swanson L, et al. Altered chromosome expression of uveal melanoma in the setting of melanocytosis. Acta Ophthalmol. 2009;87 branches of the superficial temporal artery. In fact, sur- geons usually fail to specify which branch was biopsied when they submit specimens, and no histological data exist regarding which branch is more likely to demon- strate arteritis. Recently, it was suggested that the parietal branch, rather than the frontal branch, should be biopsied in pa- tients with suspected temporal arteritis. 3 This approach eliminates the remote risk of facial nerve injury and usu- ally hides the scar behind the hairline. However, this rec- ommendation was predicated on the assumption that the prevalence of arteritis is equal in the parietal and frontal branches. We now show that selective involvement of a single vessel branch can occur in temporal arteritis. Magnetic resonance imaging has been used to com- pare the involvement of the parietal vs frontal branch in temporal arteritis. In 21 patients with suspected giant cell arteritis, involvement was rated by noting the amount of mural thickening and gadolinium enhancement of the vessel and perivascular tissue. 4 On the left side, abnor- malities were present in 14 patients in the frontal branch and in 6 patients in the parietal branch. On the right side, A Florid Arteritis Confined to a Single Branch of the Superficial Temporal Artery B iopsy of the superficial temporal artery provides vital confirmation of the diagnosis of giant cell arteritis. The vessel splits into 2 main branches: frontal and parietal. It is unknown which branch is most likely to yield a positive biopsy finding or, indeed,","PeriodicalId":8303,"journal":{"name":"Archives of ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archophthalmol.2012.1204","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30959047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Morning glory disc anomaly with peripheral retinal nonperfusion in 4 consecutive cases. 牵牛花盘异常伴视网膜周围无灌注连续4例。
Pub Date : 2012-10-01 DOI: 10.1001/archophthalmol.2012.505
Duangnate Rojanaporn, Swathi Kaliki, Carol L Shields, Jerry A Shields
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引用次数: 16
期刊
Archives of ophthalmology
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