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Effects of Virtual Reality Intervention on Motor Function and Activities of Daily Living of Children and Adolescents With Cerebral Palsy: A Systematic Review and Meta-analysis of Randomized Controlled Trials 虚拟现实干预对脑瘫儿童和青少年运动功能和日常生活活动的影响:VR与运动功能和ADL的随机对照试验的系统回顾和荟萃分析。
IF 3.7 2区 医学 Q1 REHABILITATION Pub Date : 2025-11-01 DOI: 10.1016/j.apmr.2025.06.001
Fangbo Li PhD , Weifeng Pan PhD , Jiafu Huang PhD , Lianghao Zhu PhD , Xuecheng Li PhD

Objectives

To explore the impact of virtual reality (VR) intervention on motor function (MF) and activities of daily living (ADL) in children and adolescents with cerebral palsy (CP), and to identify effective VR intervention strategies.

Data Sources

Searches were conducted in PubMed, Wiley Online Library, Embase, Cochrane Library, and Web of Science (all collections).

Study Selection

All randomized controlled trials (RCTs) of VR intervention on MF and ADL in children and adolescents with CP.

Data Extraction

We conducted dual data abstraction, quality assessment, and strength of evidence. Outcomes include gait, balance, gross MF (GMF), ADL, and hand function.

Data Synthesis

This review encompassed 41 RCTs focusing on the use of VR intervention for children and adolescents with CP. The effect of VR intervention on gait (standardized mean difference [SMD]=0.52; 95% confidence interval [CI], 0.18-0.85) and GMF (SMD=0.76; 95% CI: 0.17, 1.34) has a moderate effect, while balance (SMD=1.1; 95% CI, 0.61-1.59), ADL (SMD=1.46; 95% CI, 0.71-2.2), and hand function (SMD=1.08; 95% CI, 0.17-2) have a great effect. Subgroup analysis reveals the influence of different intervention parameters on different functions. For example, balance is related to the intervention duration of >10 weeks, the frequency of 1-2 times per week, the Nintendo Wii platform, and nonimmersive VR.

Conclusion

Although the results show that VR intervention has a positive impact on MF and ADL, the high heterogeneity limits the stability of the conclusion. Future research needs to further explore the mechanism of VR intervention and try to set a reliable personalized intervention model.
目的:探讨虚拟现实(VR)干预对脑瘫(CP)儿童和青少年运动功能(MF)和日常生活活动(ADL)的影响,并探讨有效的VR干预策略。数据来源:检索PubMed、Wiley在线图书馆、Embase、Cochrane图书馆和Web of Science(所有馆藏)。研究选择:所有VR干预对脑瘫儿童和青少年运动功能和ADL的随机对照试验。数据提取:我们进行了双重数据提取、质量评估和证据强度。结果包括步态、平衡、大运动功能、ADL和手功能。数据综合:本综述包括41项随机对照试验(RCTs),重点研究VR干预在CP儿童和青少年中的应用。95% CI: 0.18, 0.85)和粗大运动功能(SMD=0.76;95% CI: 0.17, 1.34)有中等效果,而平衡(SMD=1.1;95% ci: 0.61, 1.59),和(smd =1.46;95% CI: 0.71, 2.2)和手功能(SMD=1.08;95% CI: 0.17, 2)效果显著。亚组分析揭示了不同干预参数对不同功能的影响。例如,平衡性与干预持续时间超过10周,每周1-2次的频率,任天堂Wii平台和非沉浸式VR有关。结论:虽然结果显示VR干预对MF和ADL有正向影响,但异质性高限制了结论的稳定性。未来的研究需要进一步探索虚拟现实干预的机制,并尝试建立可靠的个性化干预模型。
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引用次数: 0
Achilles’ Tendon Experiences Reduced Depth and Volume After 3 Months of Recovery From 60 Days Bedrest 卧床60天后,3个月后,跟腱深度和体积减小;卧床后,跟腱变薄。
IF 3.7 2区 医学 Q1 REHABILITATION Pub Date : 2025-11-01 DOI: 10.1016/j.apmr.2025.08.004
T. Mark Campbell MD , Mohamed Thabet MSc , Gerd Melkus PhD , Gabriele Armbrecht MD , Guy Trudel MD

Objectives

To examine the effect of 60-days of bedrest on morphologic changes in the Achilles’ tendon using magnetic resonance imaging in 24 adults, and to explore the effects of artificial gravity (AG) by centrifugation intervention to counteract the effect of 60-days’ bedrest on such changes.

Design

Randomized controlled trial evaluating the effect of 30 minutes AG application, either continuously daily, or intermittently 6×5 minute sessions daily.

Setting

Experimental bedrest facility.

Participants

Healthy participants (N = 24) aged 24-55 years.

Interventions

continuous AG (N = 8), intermittent AG (N = 8).

Main Outcome Measures

Achilles’ tendon dimensions: depth, width, and cross-section area, volume at 2, 4, and 6 cm proximal to the tendon calcaneal insertion as baseline (baseline data collection), bedrest day-30 (HDT30) or 60 (HDT60), and during reambulation days 8, 90, and 450 (R8, R90, R450).

Results

Neither continuous nor intermittent AG interventions had any statistically significant effect on the Achilles’ tendon dimensions. No changes in the Achilles’ tendon were observed during bedrest. After 90-days of reambulation Achilles’ tendons were thinner at 2 cm with reduced volume at 2-4 cm and 4-6 cm and reduced volume 2-4 cm, 4-6 cm and 2-6 cm after 450-days of reambulation compared with baseline. Compared with day 8 of reambulation, Achilles’ tendons were thinner at 2, 4, and 6 cm from insertion and had decreased volume 2-4 cm, 4-6 cm and 2-6 cm after 450-days of reambulation.

Conclusions

This randomized controlled trial found no difference between control and AG interventions on Achilles’ tendon dimensions during 60-days of bedrest. Following 90- and 450-days of reambulation after bedrest, participants had thinner and smaller Achilles’ tendons, not prevented by AG. This study suggests that tendon changes can occur and persist after bedrest well into the reambulation phase and that clinicians should remain longitudinally vigilant for Achilles’ injury.
目的:1)利用MRI观察24例成人卧床60天对跟腱形态变化的影响,2)通过离心干预探讨人工重力(AG)抵消60天卧床对跟腱形态变化的影响。设计:随机对照试验(RCT)评估30分钟AG应用的效果,包括每天连续(cAG)或间歇性6 × 每天5分钟(iAG)。设置:实验卧床设备。参与者:24至55岁的健康参与者。主要观察指标:跟腱尺寸:深度、宽度、横截面积(CSA)、与跟腱止点近端2cm、4cm、6cm处的体积作为基线(BDC)、卧床第30天(HDT30)或第60天(HDT60)以及在复诊第8、90和450天(R8、R90、R450)。结果:cAG和iAG干预对跟腱尺寸均无统计学意义的影响。卧床期间未观察到跟腱的变化。与基线相比,重建90天后跟腱在2cm处变薄,2-4cm和4-6cm处体积减小,重建450天后跟腱在2-4cm、4-6cm和2-6cm处体积减小。与重建后第8天相比,重建后450天,跟腱在距止点2cm、4cm和6cm处变薄,体积减小2-4cm、4-6cm和2-6cm。结论:该随机对照试验发现,在60天的卧床期间,对照组和AG干预在跟腱尺寸上没有差异。卧床后90天和450天后,参与者的跟腱变细变小,并没有受到AG的影响。这项研究表明,卧床后,跟腱的变化可能发生并持续到重新活动阶段,临床医生应该对跟腱损伤保持长期警惕。
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引用次数: 0
Return to Work After Medical Rehabilitation for Musculoskeletal Disorders in Times of the COVID-19 Pandemic: A Retrospective Cohort Study COVID-19大流行时期肌肉骨骼疾病医学康复后重返工作岗位:一项回顾性队列研究
IF 3.7 2区 医学 Q1 REHABILITATION Pub Date : 2025-11-01 DOI: 10.1016/j.apmr.2025.04.001
Jan Mathis Elling PhD , Nadine Sänger MSc , Betje Schwarz DrPH , Nico Seifert MA , Christian Hetzel PhD

Objective

To describe and explain the effect of the coronavirus disease 2019 pandemic and its related measures on return to work (RTW) outcomes after multimodal medical rehabilitation for musculoskeletal disorders.

Design

Retrospective cohort study.

Setting

Three cohorts: reference (rehabilitation and RTW prepandemic), pandemic 1 (rehabilitation prepandemic, RTW during pandemic), and pandemic 2 (rehabilitation and RTW during pandemic).

Participants

Individuals who underwent multimodal medical rehabilitation for musculoskeletal disorders through the German Pension Insurance system between January 2018 and December 2021 (N=688,127).

Interventions

Not applicable.

Main Outcome Measures

A successful and stable RTW was operationalized as having employment subject to social insurance contributions from 9 to 12 months after rehabilitation.

Results

Descriptive analysis revealed an RTW rate of 67.2% in the reference cohort, a slight decline in pandemic cohort 1 (66.3%), and a more pronounced decrease in pandemic cohort 2 (63.1%). In contrast, average marginal predictions from a logistic model including various covariates showed that both pandemic cohorts (63.8% and 64.4%) exhibited similarly reduced predicted probabilities of RTW compared with the reference cohort (66.5%). Individuals with sick leave durations exceeding 6 months, compared with those with shorter sick leaves, were more negatively affected by pandemic cohort 1; however, this effect recovered in pandemic cohort 2. The interaction between cohort and income did not show any amplifying effect of the pandemic.

Conclusions

The logistic model revealed no differences in predicted probabilities of RTW between pandemic cohort 2 and pandemic cohort 1, suggesting that orthopedic rehabilitation remained robust in maintaining RTW outcomes despite pandemic-related challenges. The findings offer mixed evidence regarding the question of whether the pandemic amplified preexisting barriers to RTW.
目的描述并解释COVID-19大流行及其相关措施对肌肉骨骼疾病多模式医疗康复后重返工作岗位(RTW)结果的影响:设计:回顾性队列研究:三个队列:参考队列(大流行前的康复和复工)、大流行 1 队列(大流行前的康复、大流行期间的复工)、大流行 2 队列(大流行期间的康复和复工):主要结果测量:主要结果测量指标:成功和稳定的复工是指在康复后的第九个月至第十二个月有工作并缴纳社会保险费:描述性分析显示,参照队列的复工率为 67.2%,大流行队列 1 的复工率略有下降(66.3%),大流行队列 2 的复工率下降更为明显(63.1%)。与此相反,包含各种协变量的逻辑模型的平均边际预测结果显示,与参照队列(66.5%)相比,两个大流行队列(63.8%、64.4%)的预测复工概率都有类似的下降。与病假时间较短的人相比,病假时间超过 6 个月的人受到大流行组群 1 的负面影响更大;然而,这种影响在大流行组群 2 中有所恢复。队列与收入之间的交互作用并未显示出大流行的任何放大效应:逻辑模型显示,大流行组群 2 与大流行组群 1 之间的预测 RTW 概率没有差异,这表明尽管存在与大流行相关的挑战,矫形康复在维持 RTW 结果方面仍然很稳健。对于大流行是否扩大了原有的复健障碍这一问题,研究结果提供了不同的证据。
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引用次数: 0
Effects of a Teleexercise Movement-to-Music Intervention on Health Outcomes in Individuals With Mobility Disabilities: A Randomized Controlled Trial 远程运动对音乐干预对行动障碍者健康结果的影响:一项随机对照试验。
IF 3.7 2区 医学 Q1 REHABILITATION Pub Date : 2025-11-01 DOI: 10.1016/j.apmr.2025.05.017
Hui-Ju Young PhD , Byron Lai PhD , Jereme Wilroy PhD , Avery Vitemb MS , Shiori Tanaka PhD , Tapan S. Mehta PhD , Mohanraj Thirumalai PhD , James H. Rimmer PhD

Objective

To examine the effects of a 12-week online movement-to-music (eM2M) intervention on health outcomes in people with mobility disabilities.

Design

Two-arm randomized controlled trial.

Setting

Synchronous, online delivery over Zoom.

Participants

Adults (N=97) aged 18-70 and diagnosed with traumatic brain injury, stroke, multiple sclerosis, spinal cord injury, spina bifida, Parkinson, or cerebral palsy were randomized either to eM2M (n=48) or control (n=49).

Interventions

eM2M participants completed three 60-minute sessions weekly for 12 weeks, whereas controls maintained usual activities.

Main Outcome Measures

Primary measures included resting heart rate, heart rate recovery, and grip strength. Secondary measures included Short Physical Performance Battery (SPPB), timed Up and Go, PROMIS 10 Global Health Items, Ability to Participate in Social Roles and Activities Short Form 8a, and Godin Leisure Time Exercise Questionnaire. Participants were assessed at baseline and postintervention, with intent-to-treat mixed-model analysis of covariance as primary analyses.

Results

After adjusting for baseline and mobility groups, there was no significant between-group difference in resting heart rate postintervention, though eM2M had a greater reduction in heart rate at minute-1 recovery (LSM=33.7%, P=.04). No difference was observed in dominant hand grip strength, whereas controls showed a significantly greater increase in nondominant grip strength compared to eM2M (LSM=−1.76kg, P=.03). In contrast, eM2M demonstrated significant improvements in overall SPPB (LSM=0.52, P=.048), gait speed (LSM=0.32, P=.02), and both physical (LSM difference=2.08, P=.04) and mental (LSM=2.22, P=.02) health compared to controls. No group differences were observed in social participation. After removing outliers, eM2M showed a significant increase in physical activity compared to controls (LSM=11.55, P=.02).

Conclusions

Movement-to-music delivered online may improve cardiorespiratory fitness, mobility, quality of life, and physical activity in people with mobility disabilities.
目的:研究为期12周的在线音乐运动(eM2M)干预对行动障碍者健康结果的影响。设计:两组随机对照试验。设置:同步,通过Zoom在线交付。参与者:年龄在18至70岁之间,诊断为创伤性脑损伤、中风、多发性硬化症、脊髓损伤、脊柱裂、帕金森病或脑瘫的参与者(N=97)被随机分配到eM2M组(N= 48)或对照组(N= 49)。干预:eM2M参与者每周完成三次60分钟的会议,持续12周,而对照组保持常规活动。主要结局指标:主要指标包括静息心率、心率恢复和握力。次要测量包括短体能表现电池(SPPB)、计时起来和去、PROMIS 10全球健康项目、参与社会角色和活动的能力短表格8a和戈丁休闲时间运动问卷。在基线和干预后对参与者进行评估,意向治疗混合模型ANCOVA作为主要分析。结果:在调整基线组和活动组后,干预后静息心率组间无显著差异,尽管eM2M在1分钟恢复时心率降低幅度更大(LSM=33.7%, p=0.04)。在优势手握力方面没有观察到差异,而对照组的非优势握力与eM2M相比有明显更大的增加(LSM=-1.76kg, p=0.03)。相比之下,与对照组相比,eM2M在总体SPPB (LSM=0.52, p=0.048)、步态速度(LSM=0.32, p=0.02)、身体健康(LSM差异=2.08,p=0.04)和精神健康(LSM=2.22, p=0.02)方面均有显著改善。在社会参与方面没有观察到群体差异。在去除异常值后,与对照组相比,eM2M组的身体活动显著增加(LSM=11.55, p=0.02)。结论:在线传递的运动音乐可以改善行动不便人群的心肺健康、活动能力、生活质量和身体活动。
{"title":"Effects of a Teleexercise Movement-to-Music Intervention on Health Outcomes in Individuals With Mobility Disabilities: A Randomized Controlled Trial","authors":"Hui-Ju Young PhD ,&nbsp;Byron Lai PhD ,&nbsp;Jereme Wilroy PhD ,&nbsp;Avery Vitemb MS ,&nbsp;Shiori Tanaka PhD ,&nbsp;Tapan S. Mehta PhD ,&nbsp;Mohanraj Thirumalai PhD ,&nbsp;James H. Rimmer PhD","doi":"10.1016/j.apmr.2025.05.017","DOIUrl":"10.1016/j.apmr.2025.05.017","url":null,"abstract":"<div><h3>Objective</h3><div>To examine the effects of a 12-week online movement-to-music (eM2M) intervention on health outcomes in people with mobility disabilities.</div></div><div><h3>Design</h3><div>Two-arm randomized controlled trial.</div></div><div><h3>Setting</h3><div>Synchronous, online delivery over Zoom.</div></div><div><h3>Participants</h3><div>Adults (N=97) aged 18-70 and diagnosed with traumatic brain injury, stroke, multiple sclerosis, spinal cord injury, spina bifida, Parkinson, or cerebral palsy were randomized either to eM2M (n=48) or control (n=49).</div></div><div><h3>Interventions</h3><div>eM2M participants completed three 60-minute sessions weekly for 12 weeks, whereas controls maintained usual activities.</div></div><div><h3>Main Outcome Measures</h3><div>Primary measures included resting heart rate, heart rate recovery, and grip strength. Secondary measures included Short Physical Performance Battery (SPPB), timed Up and Go, PROMIS 10 Global Health Items, Ability to Participate in Social Roles and Activities Short Form 8a, and Godin Leisure Time Exercise Questionnaire. Participants were assessed at baseline and postintervention, with intent-to-treat mixed-model analysis of covariance as primary analyses.</div></div><div><h3>Results</h3><div>After adjusting for baseline and mobility groups, there was no significant between-group difference in resting heart rate postintervention, though eM2M had a greater reduction in heart rate at minute-1 recovery (LSM=33.7%, <em>P</em>=.04). No difference was observed in dominant hand grip strength, whereas controls showed a significantly greater increase in nondominant grip strength compared to eM2M (LSM=−1.76kg, <em>P</em>=.03). In contrast, eM2M demonstrated significant improvements in overall SPPB (LSM=0.52, <em>P</em>=.048), gait speed (LSM=0.32, <em>P</em>=.02), and both physical (LSM difference=2.08, <em>P</em>=.04) and mental (LSM=2.22, <em>P</em>=.02) health compared to controls. No group differences were observed in social participation. After removing outliers, eM2M showed a significant increase in physical activity compared to controls (LSM=11.55, <em>P</em>=.02).</div></div><div><h3>Conclusions</h3><div>Movement-to-music delivered online may improve cardiorespiratory fitness, mobility, quality of life, and physical activity in people with mobility disabilities.</div></div>","PeriodicalId":8313,"journal":{"name":"Archives of physical medicine and rehabilitation","volume":"106 11","pages":"Pages 1654-1664"},"PeriodicalIF":3.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144191413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Progressive Resistance Training on Cardiovascular Risk Factors in People With Progressive Multiple Sclerosis 进行性阻力训练对进行性多发性硬化症患者心血管危险因素的影响
IF 3.7 2区 医学 Q1 REHABILITATION Pub Date : 2025-11-01 DOI: 10.1016/j.apmr.2025.04.004
Arianne S. Gravesteijn MSc, PT , Heleen Beckerman PhD , Marloes Willig BSc , Hanneke E. Hulst PhD , Vincent de Groot PhD, MD , Brigit A. de Jong PhD, MD

Objective

To explore the natural fluctuations in cardiovascular risk factors over a 16-week extended baseline period and to investigate the effect of a 16-week progressive resistance training intervention on cardiovascular risk factors in people living with secondary progressive multiple sclerosis.

Design

Secondary analysis of a single-arm nonrandomized clinical trial with extended baseline.

Setting

Outpatient physiotherapy and rehabilitation clinics.

Participants

30 people living with secondary progressive multiple sclerosis (mean age, 54 years; 67% female).

Interventions

16-week progressive resistance training intervention (PRT).

Main Outcome Measures

Systematic COronary Risk Estimation (SCORE), Framingham Risk Score, and individual cardiovascular risk factors (ie, anthropometrics, blood pressure, lipids and lipoproteins, and glycemic controls markers) measured at week 0 (baseline), week 16 (extended baseline), and week 32 (post-PRT).

Results

Despite significant improvement in muscle strength after PRT, PRT did not yield statistically significant or clinically relevant changes in any of the cardiovascular risk parameters. Natural fluctuations during the extended baseline period were small, with intraclass correlation coefficient (ICC) values ranging from 0.717 to 0.983, except for systolic blood pressure (ICC: 0.471).

Conclusions

Our findings indicate that a 16-week PRT program did not lead to improvements in cardiovascular risk among individuals with secondary progressive multiple sclerosis. The observed natural fluctuations in cardiovascular risk factors were small in this population, with overall baseline cardiovascular risk comparable to Dutch norms.
目的:探讨16周延长基线期心血管危险因素的自然波动,并研究16周进行性阻力训练干预对继发性进行性多发性硬化症患者心血管危险因素的影响。设计:扩展基线的单臂非随机临床试验的二次分析。环境:门诊理疗和康复诊所。参与者:30例继发性进展性多发性硬化症患者(平均年龄54岁;67%的女性)。干预措施:16周进行性抗阻训练干预(PRT)。主要结局指标:在第0周(基线)、第16周(延长基线)和第32周(prt后)测量的系统性冠状动脉风险评估(SCORE)、Framingham风险评分和个体心血管危险因素(即人体测量、血压、脂质和脂蛋白以及血糖控制标志物)。结果:尽管PRT后肌肉力量有显著改善,但PRT在任何心血管危险参数方面没有产生统计学意义或临床相关的变化。在延长的基线期间,自然波动较小,除收缩压(ICC: 0.471)外,类内相关系数(ICC)值在0.717至0.983之间。结论:我们的研究结果表明,16周的PRT计划并没有导致继发性进行性多发性硬化症患者心血管风险的改善。观察到的心血管危险因素的自然波动在该人群中很小,总体基线心血管风险与荷兰标准相当。
{"title":"Effects of Progressive Resistance Training on Cardiovascular Risk Factors in People With Progressive Multiple Sclerosis","authors":"Arianne S. Gravesteijn MSc, PT ,&nbsp;Heleen Beckerman PhD ,&nbsp;Marloes Willig BSc ,&nbsp;Hanneke E. Hulst PhD ,&nbsp;Vincent de Groot PhD, MD ,&nbsp;Brigit A. de Jong PhD, MD","doi":"10.1016/j.apmr.2025.04.004","DOIUrl":"10.1016/j.apmr.2025.04.004","url":null,"abstract":"<div><h3>Objective</h3><div>To explore the natural fluctuations in cardiovascular risk factors over a 16-week extended baseline period and to investigate the effect of a 16-week progressive resistance training intervention on cardiovascular risk factors in people living with secondary progressive multiple sclerosis.</div></div><div><h3>Design</h3><div>Secondary analysis of a single-arm nonrandomized clinical trial with extended baseline.</div></div><div><h3>Setting</h3><div>Outpatient physiotherapy and rehabilitation clinics.</div></div><div><h3>Participants</h3><div>30 people living with secondary progressive multiple sclerosis (mean age, 54 years; 67% female).</div></div><div><h3>Interventions</h3><div>16-week progressive resistance training intervention (PRT).</div></div><div><h3>Main Outcome Measures</h3><div>Systematic COronary Risk Estimation (SCORE), Framingham Risk Score, and individual cardiovascular risk factors (ie, anthropometrics, blood pressure, lipids and lipoproteins, and glycemic controls markers) measured at week 0 (baseline), week 16 (extended baseline), and week 32 (post-PRT).</div></div><div><h3>Results</h3><div>Despite significant improvement in muscle strength after PRT, PRT did not yield statistically significant or clinically relevant changes in any of the cardiovascular risk parameters. Natural fluctuations during the extended baseline period were small, with intraclass correlation coefficient (ICC) values ranging from 0.717 to 0.983, except for systolic blood pressure (ICC: 0.471).</div></div><div><h3>Conclusions</h3><div>Our findings indicate that a 16-week PRT program did not lead to improvements in cardiovascular risk among individuals with secondary progressive multiple sclerosis. The observed natural fluctuations in cardiovascular risk factors were small in this population, with overall baseline cardiovascular risk comparable to Dutch norms.</div></div>","PeriodicalId":8313,"journal":{"name":"Archives of physical medicine and rehabilitation","volume":"106 11","pages":"Pages 1694-1702"},"PeriodicalIF":3.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143959750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ed Board page 教育版面
IF 3.7 2区 医学 Q1 REHABILITATION Pub Date : 2025-11-01 DOI: 10.1016/S0003-9993(25)00947-5
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引用次数: 0
Refining Maximal Heart Rate Estimation to Enhance Exercise Recommendations for Persons With Parkinson Disease 改进最大心率估算以增强帕金森病患者的运动建议
IF 3.7 2区 医学 Q1 REHABILITATION Pub Date : 2025-11-01 DOI: 10.1016/j.apmr.2025.03.046
Anson B. Rosenfeldt PT, DPT, MBA , Amanda L. Penko PhD , Amy Elizabeth Jansen MPH , Cielita Lopez-Lennon PT, DPT , Eric Zimmerman MS , Peter B. Imrey PhD , Tamanna K. Singh MD , Leland E. Dibble PT, PhD , Jay L. Alberts PhD

Objective

To derive and evaluate an alternative equation to estimate maximal heart rate in persons with Parkinson disease (PD) in the absence of structured exercise testing using observed maximal heart rate data from a maximal cardiopulmonary exercise test (CPET) and basic demographic and clinical data.

Design

Baseline data from a randomized controlled trial.

Setting

Academic Medical Center.

Participants

Eighty-two persons with mild-to-moderate PD who completed a CPET.

Interventions

Not applicable.

Main Outcome Measures

A linear regression model was fit to maximal heart rate from CPET using the relaxed least absolute shrinkage and selection operator (lasso) and 7 readily clinically accessible candidate covariables. Model fit was assessed by leave-one-out cross-validation. Maximal heart rates from the CPET were compared with estimates from the regression model and from 2 traditional age-based maximal heart rate estimators: (220 – age) and [208 − (0.7 × age)].

Results

The regression-based heart rate estimator was [166 − (1.15 × age) + (0.60 × resting heart rate)] and most closely fit the observed maximal heart rate from the CPET. The (220 − age) and [208 − (0.7 × age)] equations overestimated maximal heart rate for 88% and 94% of the participants, respectively. The mean square error of the regression-based estimator was 63% and 75% lower than those of the 2 traditional age-based estimators, respectively.

Conclusions

Overestimating maximal heart rate generates prescribed target heart rate zones that are likely unachievable during aerobic exercise. The proposed regression-based maximal heart rate estimator most closely fit observed maximal heart rates from the CPET. Adoption of this estimator, based on both age and resting heart rate, may improve estimated maximal heart rate accuracy and thus provide more appropriate and achievable exercise heart rate zones for persons with PD in the absence of a CPET.
目的:利用最大心肺运动试验(CPET)观察到的最大HR数据和基本的人口统计学和临床数据,推导并评估在没有结构化运动试验的情况下,PwPD患者最大HR的替代方程。设计:基线数据来自随机临床试验设置:学术医疗中心参与者:82名完成CPET干预的轻中度PD患者:不适用主要结果测量:使用放宽的最小绝对收缩和选择算子(lasso)和7个易于临床获取的候选协变量,线性回归模型拟合CPET的最大HR。模型拟合通过留一交叉验证进行评估。将CPET的最大HR与回归模型的估计值以及两种传统的基于年龄的最大HR估计值(220-age)和[208 - (0.7*age)]进行比较。结果:基于回归的HR估计值为[166 -(1.15 *年龄) + (0.60 *静息HR)],与CPET观察到的最大HR最接近。(220-age)和[208 - (0.7*age)]方程分别高估了88%和94%的参与者的最大HR。与传统的两种基于年龄的估计方法相比,基于回归的估计方法的均方误差分别低63%和75%。结论:高估最大心率会产生在有氧运动中可能无法达到的规定目标心率区。所提出的基于回归的最大HR估计最接近CPET观测到的最大HR。采用这种基于年龄和静息心率的估计方法,可以提高估计的最大心率准确性,从而在没有CPET的情况下为PwPD提供更合适和可实现的运动心率区域。
{"title":"Refining Maximal Heart Rate Estimation to Enhance Exercise Recommendations for Persons With Parkinson Disease","authors":"Anson B. Rosenfeldt PT, DPT, MBA ,&nbsp;Amanda L. Penko PhD ,&nbsp;Amy Elizabeth Jansen MPH ,&nbsp;Cielita Lopez-Lennon PT, DPT ,&nbsp;Eric Zimmerman MS ,&nbsp;Peter B. Imrey PhD ,&nbsp;Tamanna K. Singh MD ,&nbsp;Leland E. Dibble PT, PhD ,&nbsp;Jay L. Alberts PhD","doi":"10.1016/j.apmr.2025.03.046","DOIUrl":"10.1016/j.apmr.2025.03.046","url":null,"abstract":"<div><h3>Objective</h3><div>To derive and evaluate an alternative equation to estimate maximal heart rate in persons with Parkinson disease (PD) in the absence of structured exercise testing using observed maximal heart rate data from a maximal cardiopulmonary exercise test (CPET) and basic demographic and clinical data.</div></div><div><h3>Design</h3><div>Baseline data from a randomized controlled trial.</div></div><div><h3>Setting</h3><div>Academic Medical Center.</div></div><div><h3>Participants</h3><div>Eighty-two persons with mild-to-moderate PD who completed a CPET.</div></div><div><h3>Interventions</h3><div>Not applicable.</div></div><div><h3>Main Outcome Measures</h3><div>A linear regression model was fit to maximal heart rate from CPET using the relaxed least absolute shrinkage and selection operator (lasso) and 7 readily clinically accessible candidate covariables. Model fit was assessed by leave-one-out cross-validation. Maximal heart rates from the CPET were compared with estimates from the regression model and from 2 traditional age-based maximal heart rate estimators: (220 – age) and [208 − (0.7 × age)].</div></div><div><h3>Results</h3><div>The regression-based heart rate estimator was [166 − (1.15 × age) + (0.60 × resting heart rate)] and most closely fit the observed maximal heart rate from the CPET. The (220 − age) and [208 − (0.7 × age)] equations overestimated maximal heart rate for 88% and 94% of the participants, respectively. The mean square error of the regression-based estimator was 63% and 75% lower than those of the 2 traditional age-based estimators, respectively.</div></div><div><h3>Conclusions</h3><div>Overestimating maximal heart rate generates prescribed target heart rate zones that are likely unachievable during aerobic exercise. The proposed regression-based maximal heart rate estimator most closely fit observed maximal heart rates from the CPET. Adoption of this estimator, based on both age and resting heart rate, may improve estimated maximal heart rate accuracy and thus provide more appropriate and achievable exercise heart rate zones for persons with PD in the absence of a CPET.</div></div>","PeriodicalId":8313,"journal":{"name":"Archives of physical medicine and rehabilitation","volume":"106 11","pages":"Pages 1680-1684"},"PeriodicalIF":3.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of Blended Learning in Enhancing Self-Efficacy and Medication Adherence in Cardiac Rehabilitation for Individuals Undergoing Coronary Artery Bypass Surgery: A Randomized Control Trial 混合学习在冠状动脉搭桥术患者心脏康复中提高自我效能和药物依从性的作用:一项随机对照试验:混合学习在心脏康复中的作用
IF 3.7 2区 医学 Q1 REHABILITATION Pub Date : 2025-11-01 DOI: 10.1016/j.apmr.2025.05.011
Ghazal Veisi MSc , Fatemeh Pakrad PhD , Robbert Gobbens PhD , Younes Mohammadi PhD , Lobat Majidi MD

Objective

This study aimed to evaluate the effectiveness of a traditional cardiac rehabilitation (CR) program compared with an augmented program that integrates traditional CR with face-to-face training sessions and remote assistance facilitated through an application based on the knowledge, attitudes, and practices model for individuals undergoing coronary artery bypass graft (CABG) surgery.

Design

A randomized controlled trial with a blinded outcome assessment was used (IRCT20230902059333N1).

Setting

A major heart center in a middle-income country.

Participants

Of the 80 patients referred to the CR program during the study, 70 patients (N=70) were successfully enrolled, reaching the target sample size. Participants were randomly assigned in a 1:1 ratio, resulting in 35 patients per group.

Interventions

In addition to traditional CR, patients participated in 4 in-person training sessions throughout the rehabilitation process and received 3 months of follow-up support via the app after completing the program.

Main Outcome Measures

Medication adherence and self-efficacy were assessed before the initiation of CR, immediately after its completion, and 3 months postcompletion.

Results

There were no significant demographic differences between the intervention and control groups. However, throughout the study, significant differences emerged in favor of the 3 groups concerning medication adherence and self-efficacy (P<.001). The intervention group showed substantial and continuous improvements in medication adherence and self-efficacy scores, which were evident from the 1st month and persisted over time.

Conclusions

Implementing a blended learning approach in CR has demonstrated benefits in medication adherence and self-efficacy, highlighting the necessity for further research and clinical application.
目的:本研究旨在评估传统心脏康复(CR)计划与增强计划的有效性,增强计划将传统心脏康复与面对面培训课程相结合,并通过基于知识、态度和实践(KAP)模型的应用程序促进远程援助,用于接受冠状动脉搭桥术(CABG)手术的个体。设计:采用随机对照试验,采用盲法结局评估(IRCT20230902059333N1)。环境:中等收入国家的主要心脏中心。参与者:在研究期间涉及心脏康复计划的80名患者中,70名患者成功入组,达到目标样本量。参与者按1:1的比例随机分配,每组35名患者。干预:除了传统的心脏康复外,患者在整个康复过程中还参加了四次面对面的培训,并在完成项目后通过app接受了三个月的随访支持。主要观察指标:分别在心脏康复开始前、康复结束后和康复结束后3个月对患者的药物依从性和自我效能感进行评估。结果:干预组与对照组在人口统计学上无显著差异。然而,在整个研究过程中,3组在药物依从性和自我效能感方面出现了显著差异(p结论:在心脏康复中实施混合学习方法在药物依从性和自我效能感方面表现出益处,需要进一步研究和临床应用。
{"title":"Role of Blended Learning in Enhancing Self-Efficacy and Medication Adherence in Cardiac Rehabilitation for Individuals Undergoing Coronary Artery Bypass Surgery: A Randomized Control Trial","authors":"Ghazal Veisi MSc ,&nbsp;Fatemeh Pakrad PhD ,&nbsp;Robbert Gobbens PhD ,&nbsp;Younes Mohammadi PhD ,&nbsp;Lobat Majidi MD","doi":"10.1016/j.apmr.2025.05.011","DOIUrl":"10.1016/j.apmr.2025.05.011","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to evaluate the effectiveness of a traditional cardiac rehabilitation (CR) program compared with an augmented program that integrates traditional CR with face-to-face training sessions and remote assistance facilitated through an application based on the knowledge, attitudes, and practices model for individuals undergoing coronary artery bypass graft (CABG) surgery.</div></div><div><h3>Design</h3><div>A randomized controlled trial with a blinded outcome assessment was used (IRCT20230902059333N1).</div></div><div><h3>Setting</h3><div>A major heart center in a middle-income country.</div></div><div><h3>Participants</h3><div>Of the 80 patients referred to the CR program during the study, 70 patients (N=70) were successfully enrolled, reaching the target sample size. Participants were randomly assigned in a 1:1 ratio, resulting in 35 patients per group.</div></div><div><h3>Interventions</h3><div>In addition to traditional CR, patients participated in 4 in-person training sessions throughout the rehabilitation process and received 3 months of follow-up support via the app after completing the program.</div></div><div><h3>Main Outcome Measures</h3><div>Medication adherence and self-efficacy were assessed before the initiation of CR, immediately after its completion, and 3 months postcompletion.</div></div><div><h3>Results</h3><div>There were no significant demographic differences between the intervention and control groups. However, throughout the study, significant differences emerged in favor of the 3 groups concerning medication adherence and self-efficacy (<em>P</em>&lt;.001). The intervention group showed substantial and continuous improvements in medication adherence and self-efficacy scores, which were evident from the 1st month and persisted over time.</div></div><div><h3>Conclusions</h3><div>Implementing a blended learning approach in CR has demonstrated benefits in medication adherence and self-efficacy, highlighting the necessity for further research and clinical application.</div></div>","PeriodicalId":8313,"journal":{"name":"Archives of physical medicine and rehabilitation","volume":"106 11","pages":"Pages 1645-1653"},"PeriodicalIF":3.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144232981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inclusion of Racially and Ethnically Diverse Samples in Cognitive Rehabilitation Research: An Ethnographic Study of Recruitment and Retention Practices 认知康复研究中种族和民族多样性样本的纳入:招募和保留实践的民族志研究。
IF 3.7 2区 医学 Q1 REHABILITATION Pub Date : 2025-11-01 DOI: 10.1016/j.apmr.2025.03.043
Jessica Kersey PhD, OTR/L , Christian Le , Emily Evans PT, PhD , Zaccheus J. Ahonle PhD, CRC , Patricia Garcia PsyD, HSPP , Anthony H. Lequerica PhD , Devina Kumar PhD, MSc, PT , Devan Parrott PhD

Objective

To describe the recruitment and retention practices of brain injury rehabilitation researchers and factors affecting the inclusion of racially and ethnically diverse research participants.

Design

Ethnographic study using surveys and qualitative interviews.

Setting

Virtual.

Participants

Eleven investigators (N=11) who published cognitive rehabilitation intervention studies.

Interventions

Not applicable.

Main Outcome Measures

Participants completed a survey describing strategies that have shown promise for the recruitment and retention of diverse participants. They then completed a qualitative interview to describe their priorities, the perceived effectiveness of their practices, and the challenges to recruiting representative samples. Interviews were analyzed using thematic analysis.

Results

Investigators reported moderate confidence in their knowledge of promising recruitment strategies but low confidence in implementing those strategies. Qualitative themes were balancing competing recruitment and retention priorities, building relationships with participants and communities, and research infrastructure and policies. Key factors influencing recruitment and retention practices included research study and research team characteristics, institutional infrastructure and policies, local contextual factors, and national academic community infrastructure and norms.

Conclusions

Brain injury rehabilitation research faces significant challenges in achieving representation of racially and ethnically diverse participants. Systemic changes are needed at the study, institutional, and national levels to support more equitable clinical trial enrollment and reduce health disparities for marginalized brain injury survivors.
目的:描述脑损伤康复研究人员的招募和保留做法以及影响种族和民族多元化研究参与者纳入的因素。设计:使用调查和定性访谈进行人种学研究。设置:虚拟。参与者:11名发表认知康复干预研究的研究者。主要结果:参与者完成了一项调查,描述了在招募和留住不同参与者方面显示出希望的策略。然后,他们完成了一个定性访谈,以描述他们的优先事项、他们实践的感知有效性,以及招募代表性样本的挑战。访谈采用专题分析进行分析。结果:调查人员报告了他们对有希望的招聘策略的知识的中等信心,但对实施这些策略的信心较低。定性主题是1)平衡竞争性招聘和保留优先级,2)与参与者和社区建立关系,以及3)研究基础设施和政策。影响招聘和留用实践的关键因素包括研究学习和研究团队特征、机构基础设施和政策、地方背景因素和国家学术团体基础设施和规范。结论:脑损伤康复研究在实现不同种族和民族参与者的代表性方面面临着重大挑战。需要在研究、机构和国家层面进行系统性改革,以支持更公平的临床试验招募,并减少边缘化脑损伤幸存者的健康差距。
{"title":"Inclusion of Racially and Ethnically Diverse Samples in Cognitive Rehabilitation Research: An Ethnographic Study of Recruitment and Retention Practices","authors":"Jessica Kersey PhD, OTR/L ,&nbsp;Christian Le ,&nbsp;Emily Evans PT, PhD ,&nbsp;Zaccheus J. Ahonle PhD, CRC ,&nbsp;Patricia Garcia PsyD, HSPP ,&nbsp;Anthony H. Lequerica PhD ,&nbsp;Devina Kumar PhD, MSc, PT ,&nbsp;Devan Parrott PhD","doi":"10.1016/j.apmr.2025.03.043","DOIUrl":"10.1016/j.apmr.2025.03.043","url":null,"abstract":"<div><h3>Objective</h3><div>To describe the recruitment and retention practices of brain injury rehabilitation researchers and factors affecting the inclusion of racially and ethnically diverse research participants.</div></div><div><h3>Design</h3><div>Ethnographic study<span> using surveys and qualitative interviews.</span></div></div><div><h3>Setting</h3><div>Virtual.</div></div><div><h3>Participants</h3><div>Eleven investigators (N=11) who published cognitive rehabilitation intervention studies.</div></div><div><h3>Interventions</h3><div>Not applicable.</div></div><div><h3>Main Outcome Measures</h3><div>Participants completed a survey describing strategies that have shown promise for the recruitment and retention of diverse participants. They then completed a qualitative interview to describe their priorities, the perceived effectiveness of their practices, and the challenges to recruiting representative samples. Interviews were analyzed using thematic analysis.</div></div><div><h3>Results</h3><div>Investigators reported moderate confidence in their knowledge of promising recruitment strategies but low confidence in implementing those strategies. Qualitative themes were balancing competing recruitment and retention priorities, building relationships with participants and communities, and research infrastructure and policies. Key factors influencing recruitment and retention practices included research study and research team characteristics, institutional infrastructure and policies, local contextual factors, and national academic community infrastructure and norms.</div></div><div><h3>Conclusions</h3><div><span>Brain injury rehabilitation research faces significant challenges in achieving representation of racially and ethnically diverse participants. Systemic changes are needed at the study, institutional, and national levels to support more equitable clinical trial enrollment and reduce </span>health disparities for marginalized brain injury survivors.</div></div>","PeriodicalId":8313,"journal":{"name":"Archives of physical medicine and rehabilitation","volume":"106 11","pages":"Pages 1665-1671"},"PeriodicalIF":3.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Archives Supplements 档案补充
IF 3.7 2区 医学 Q1 REHABILITATION Pub Date : 2025-11-01 DOI: 10.1016/S0003-9993(25)00959-1
{"title":"Archives Supplements","authors":"","doi":"10.1016/S0003-9993(25)00959-1","DOIUrl":"10.1016/S0003-9993(25)00959-1","url":null,"abstract":"","PeriodicalId":8313,"journal":{"name":"Archives of physical medicine and rehabilitation","volume":"106 11","pages":"Pages 1785-1787"},"PeriodicalIF":3.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145398119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Archives of physical medicine and rehabilitation
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