For about 35 years the author has despaired of most of our dentists. In lectures he has often described the majority of dentists as the gravediggers of the people. This has hardly changed since then. While early dentists used to prefer a revealing therapy (see back to the barbers, followed by the dentists), i.e. pulling out diseased teeth, a covering therapy has developed in the last decades. One tries to preserve diseased teeth, among other things with root canal treatments. The more academic dentistry became, the more the relationship between foreign substances in the mouth and the health of the whole body was ignored.
{"title":"Re-print-Significant Findings in Tooth Roots and Jaw Bones Can Cause Serious Diseases","authors":"Doepp Manfred","doi":"10.31579/2693-4779/100","DOIUrl":"https://doi.org/10.31579/2693-4779/100","url":null,"abstract":"For about 35 years the author has despaired of most of our dentists. In lectures he has often described the majority of dentists as the gravediggers of the people. This has hardly changed since then. While early dentists used to prefer a revealing therapy (see back to the barbers, followed by the dentists), i.e. pulling out diseased teeth, a covering therapy has developed in the last decades. One tries to preserve diseased teeth, among other things with root canal treatments. The more academic dentistry became, the more the relationship between foreign substances in the mouth and the health of the whole body was ignored.","PeriodicalId":8525,"journal":{"name":"Applied Clinical Research, Clinical Trials and Regulatory Affairs","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78573434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Foreign body of digestive tract refers to the noninherent substances retained in the digestive tract caused by various reasons. Foreign body incarceration is one of the clinical emergencies, occurs at all ages, whose incidence is second only to gastrointestinal bleeding, accounting for about 4% of emergency endoscopic diagnosis and treatment. If not treated timely, foreign body incarceration may cause gastrointestinal erosion, ulcer, bleeding, perforation, obstruction and aortic rupture which is life-threatening. According to the characteristics of patients, dietetical characteristic, types of gastrointestinal foreign bodies, retention time of foreign bodies, incarcerated sites, clinical manifestations, complications, treatment methods, average length of stay and expenses, we explore the research progress of gastrointestinal foreign bodies to improve the level of diagnosis and treatment, as well as increase the cure rate and reduce complications. This review aims to summarize the clinical diagnosis and treatment methods of gastrointestinal foreign bodies for clinicians and strengthen readers' understanding of gastrointestinal foreign bodies.
{"title":"Clinical Research Progress of Foreign Bodies in Digestive Tract","authors":"Dao-Hui Wei, Wei Liu","doi":"10.31579/2693-4779/093","DOIUrl":"https://doi.org/10.31579/2693-4779/093","url":null,"abstract":"Foreign body of digestive tract refers to the noninherent substances retained in the digestive tract caused by various reasons. Foreign body incarceration is one of the clinical emergencies, occurs at all ages, whose incidence is second only to gastrointestinal bleeding, accounting for about 4% of emergency endoscopic diagnosis and treatment. If not treated timely, foreign body incarceration may cause gastrointestinal erosion, ulcer, bleeding, perforation, obstruction and aortic rupture which is life-threatening. According to the characteristics of patients, dietetical characteristic, types of gastrointestinal foreign bodies, retention time of foreign bodies, incarcerated sites, clinical manifestations, complications, treatment methods, average length of stay and expenses, we explore the research progress of gastrointestinal foreign bodies to improve the level of diagnosis and treatment, as well as increase the cure rate and reduce complications. This review aims to summarize the clinical diagnosis and treatment methods of gastrointestinal foreign bodies for clinicians and strengthen readers' understanding of gastrointestinal foreign bodies.","PeriodicalId":8525,"journal":{"name":"Applied Clinical Research, Clinical Trials and Regulatory Affairs","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90873026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Karavdić, A. Firdus, M. A., Đogić H, Altunbabić L, Dewan P.A
Self-inserted urethrovesical foreign bodies are rare in children. A 7-year-old boy inserted a hairpin into the urethra seven days before admission, a diagnosis that was made on the basis of the appearance of blood in the urine, palpation of the base of the penis and two directional X-ray imaging. Cystourethroscopy and suprapubic cystotomy were used to remove the foreign body.The presentation of urethrovesical foreign bodies can vary widely, as can the type of object inserted. Definitive treatment is usually the endoscopic removal, however occasionally surgical intervention may be required. Our novel approach enabled less traumatic removal of the hairpin
{"title":"Combined Extraction (Cystourethroscopy and Suprapubic Cystotomy) of A Selfinserted Hairpin Located In The Posterior Urethra - A 7-Year-Old Boy","authors":"K. Karavdić, A. Firdus, M. A., Đogić H, Altunbabić L, Dewan P.A","doi":"10.31579/2693-4779/097","DOIUrl":"https://doi.org/10.31579/2693-4779/097","url":null,"abstract":"Self-inserted urethrovesical foreign bodies are rare in children. A 7-year-old boy inserted a hairpin into the urethra seven days before admission, a diagnosis that was made on the basis of the appearance of blood in the urine, palpation of the base of the penis and two directional X-ray imaging. Cystourethroscopy and suprapubic cystotomy were used to remove the foreign body.The presentation of urethrovesical foreign bodies can vary widely, as can the type of object inserted. Definitive treatment is usually the endoscopic removal, however occasionally surgical intervention may be required. Our novel approach enabled less traumatic removal of the hairpin","PeriodicalId":8525,"journal":{"name":"Applied Clinical Research, Clinical Trials and Regulatory Affairs","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75358176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Corina Florica Ioniță, A. Gomotirceanu, Daniela Cojocaru, F. Costea, O. Pop
The Zinner Syndrome is a rare congenital malformation represented by a triad of characteristics: ipsilateral renal agenesis, seminal vesicle cysts and ejaculatory duct obstruction. The aim of this study is to present a 69 year old man case, with seminal vesicle adenocarcinoma developed in association with Zinner Syndrome.First off all, patient presented with severe urinary retention. Had clinical and imaging examinations: ultrasound scan, computed tomography of the chest, abdomen and pelvis, abdominal-pelvic MRI and biochemical evaluation: PSA. As a result, diagnosis of Zinner Syndrome has been established and was suspected a carcinoma of seminal vesicle. The pacient underwent robotic removal of the tumoral cyst. The postoperative evolution of the patient was uneventful. The diagnosis of seminal vesicle adenocarcinoma was confirmed by immunohistochemistry, staining negative for PSA and positive for CK7. Seminal vesicle carcinomas are particularly rare. Their occurrence in patients with Zinner Syndrome is exceptional, but should be considered in differential diagnosis of pelvic tumors.
{"title":"Seminal Vesicle Adenocarcinoma Associated with Zinner Syndrome: Case Report and Literature Review","authors":"Corina Florica Ioniță, A. Gomotirceanu, Daniela Cojocaru, F. Costea, O. Pop","doi":"10.31579/2693-4779/099","DOIUrl":"https://doi.org/10.31579/2693-4779/099","url":null,"abstract":"The Zinner Syndrome is a rare congenital malformation represented by a triad of characteristics: ipsilateral renal agenesis, seminal vesicle cysts and ejaculatory duct obstruction. The aim of this study is to present a 69 year old man case, with seminal vesicle adenocarcinoma developed in association with Zinner Syndrome.First off all, patient presented with severe urinary retention. Had clinical and imaging examinations: ultrasound scan, computed tomography of the chest, abdomen and pelvis, abdominal-pelvic MRI and biochemical evaluation: PSA. As a result, diagnosis of Zinner Syndrome has been established and was suspected a carcinoma of seminal vesicle. The pacient underwent robotic removal of the tumoral cyst. The postoperative evolution of the patient was uneventful. The diagnosis of seminal vesicle adenocarcinoma was confirmed by immunohistochemistry, staining negative for PSA and positive for CK7. Seminal vesicle carcinomas are particularly rare. Their occurrence in patients with Zinner Syndrome is exceptional, but should be considered in differential diagnosis of pelvic tumors.","PeriodicalId":8525,"journal":{"name":"Applied Clinical Research, Clinical Trials and Regulatory Affairs","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87525168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jehovah’s witness refusion to blood products is based on the interpretation of the bible as blood transfusion carries itself potential risks and is a special issue in this group of patients this report suggest that blood transfusion should be guided by personal triggers, based on hemodynamic and laboratory indices associated with age and comorbidities.
{"title":"Conservative Blood Management and Parameters That We Should Take into Account to Avoid Transfusions in A Jehovah’s Witness Patient","authors":"Marina Ayres Delgado, Luana Assis Ferreira, Lorena Machado Marques Faria, Jadson Lardy Lemes","doi":"10.31579/2693-4779/098","DOIUrl":"https://doi.org/10.31579/2693-4779/098","url":null,"abstract":"Jehovah’s witness refusion to blood products is based on the interpretation of the bible as blood transfusion carries itself potential risks and is a special issue in this group of patients this report suggest that blood transfusion should be guided by personal triggers, based on hemodynamic and laboratory indices associated with age and comorbidities.","PeriodicalId":8525,"journal":{"name":"Applied Clinical Research, Clinical Trials and Regulatory Affairs","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77288592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cryotherapy which is also referred to as cryosurgery or cryoablation refers to utilization of very cold temperatures to freeze various cells depending upon the pathology. Cryotherapy has tended to be utilized as treatment of curative intent for localized low-risk and intermediate risk carcinomas of the prostate gland. Cryotherapy has also been utilized for the treatment of post-cryotherapy failure prostate cancers with residual tumour or locally recurrent tumour that is confined to the prostate gland. Cryotherapy has also been utilized for the treatment of locally recurrent prostate cancers or localized prostate cancers that have remained following failure of radiotherapy to the prostate cancer of curative intent or radical prostatectomy of prostate for prostate at times. Because cryotherapy of prostate cancer is a minimally invasive treatment procedure, it can be utilized in the treatment of patients who have localized prostate cancer whose tumours could be treated by means of radical prostatectomy or radiotherapy (external beam radiotherapy or brachytherapy) who are considered not to be medically fit to undergo these procedures because of their co-morbidities. The most common treatment options for the management of localized adenocarcinomas of the prostate gland tend to involve radical prostatectomy or radical radiotherapy. Nevertheless, other treatment options for localized prostate cancer that have been undertaken sporadically include: Radiofrequency ablation of the prostate cancer, High intensity focussed ultrasound scan treatment of prostate cancer, irreversible electroporation of prostate cancer. Cryotherapy of prostate cancer as treatment of curative intent has tended to be published sporadically based upon case reports or case series and there has not been reports of an extensive clinical-trials on cryotherapy of localized adenocarcinoma of the prostate. Furthermore, there is no consensus opinion validated definition of biochemical failure pursuant to treatment of localized prostate cancer by cryotherapy. Nevertheless, one article has reported a prospective study with the undertaking of standardized follow-up protocol in which it a series of 108 patients who were diagnosed as having localized adenocarcinoma of prostate that was staged T1c to T2c were treated by primary cryoablation of curative intent and in which the median follow-up was 61 months. With regard to the results of this study, the criteria of biochemical recurrence had been unified based upon the American Society for Therapeutic Radiology and Oncology (ASTRO). The end points of the study included: biochemical progression-free survival (BPFS), cancer-specific survival, as well as overall survival. The complication rates were reported in the study. With regard to the results the biochemical progression-free survival rates were for low-, medium-, and high-risk prostate cancer patients 96.4%, 91.2%, and 62.2%, respectively. The Cancer-specific survival was 98.1%. The overall sur
{"title":"Cryotherapy As Treatment of Curative Intent for Localized Adenocarcinoma of The Prostate Gland with A Focus on Low-risk and Medium – (Intermediate-) Risk Localized Adenocarcinoma of The Prostate Gland: A Review and Update","authors":"A. Kodzo-Grey Venyo","doi":"10.31579/2693-4779/083","DOIUrl":"https://doi.org/10.31579/2693-4779/083","url":null,"abstract":"Cryotherapy which is also referred to as cryosurgery or cryoablation refers to utilization of very cold temperatures to freeze various cells depending upon the pathology. Cryotherapy has tended to be utilized as treatment of curative intent for localized low-risk and intermediate risk carcinomas of the prostate gland. Cryotherapy has also been utilized for the treatment of post-cryotherapy failure prostate cancers with residual tumour or locally recurrent tumour that is confined to the prostate gland. Cryotherapy has also been utilized for the treatment of locally recurrent prostate cancers or localized prostate cancers that have remained following failure of radiotherapy to the prostate cancer of curative intent or radical prostatectomy of prostate for prostate at times. Because cryotherapy of prostate cancer is a minimally invasive treatment procedure, it can be utilized in the treatment of patients who have localized prostate cancer whose tumours could be treated by means of radical prostatectomy or radiotherapy (external beam radiotherapy or brachytherapy) who are considered not to be medically fit to undergo these procedures because of their co-morbidities. The most common treatment options for the management of localized adenocarcinomas of the prostate gland tend to involve radical prostatectomy or radical radiotherapy. Nevertheless, other treatment options for localized prostate cancer that have been undertaken sporadically include: Radiofrequency ablation of the prostate cancer, High intensity focussed ultrasound scan treatment of prostate cancer, irreversible electroporation of prostate cancer. Cryotherapy of prostate cancer as treatment of curative intent has tended to be published sporadically based upon case reports or case series and there has not been reports of an extensive clinical-trials on cryotherapy of localized adenocarcinoma of the prostate. Furthermore, there is no consensus opinion validated definition of biochemical failure pursuant to treatment of localized prostate cancer by cryotherapy. Nevertheless, one article has reported a prospective study with the undertaking of standardized follow-up protocol in which it a series of 108 patients who were diagnosed as having localized adenocarcinoma of prostate that was staged T1c to T2c were treated by primary cryoablation of curative intent and in which the median follow-up was 61 months. With regard to the results of this study, the criteria of biochemical recurrence had been unified based upon the American Society for Therapeutic Radiology and Oncology (ASTRO). The end points of the study included: biochemical progression-free survival (BPFS), cancer-specific survival, as well as overall survival. The complication rates were reported in the study. With regard to the results the biochemical progression-free survival rates were for low-, medium-, and high-risk prostate cancer patients 96.4%, 91.2%, and 62.2%, respectively. The Cancer-specific survival was 98.1%. The overall sur","PeriodicalId":8525,"journal":{"name":"Applied Clinical Research, Clinical Trials and Regulatory Affairs","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87563989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The remedial use of camel urine has been known for centuries, with evidence of its use for curative purposes found in early folklore. It has been used to cure different diseases; however, the significant therapeutic benefits of urine have yet to undergo rigorous scientific evaluation. The exploration of the use of camel urine is of great interest to determine their efficacy in pharmaceutical industry. This study investigated the effect of camel’s urine against five human pathogenic bacteria, to determine their efficacy against multidrug resistant microbes. The probe was done by agar well diffusion method. Multidrug resistant (MDR) strains of Bacillus subtilis (ATCC 6633), E. coli (ATCC 8739), Salmonella enterica (ATCC 14028), Staphylococcus aureus (ATCC 6538), Pseudomonas aeruginosa (ATCC 27853) were used in the study. Ciprofloxacin was used as standard. Maximum zone of inhibition was observed with Salmonella enterica which is 33 ± 0.2 mm. Additionally, Multidrug resistant (MDR) strains of E. coli, Pseudomonas aeruginosa and Staphylococcus aureus was strongly inhibited by camel’s urine. Moreover, MDR strains of Bacillus subtilis, also shows inhibition. The potency shown by camel’s urine for therapeutic action, recommends their use against multidrug resistant microorganisms. In this research work, scientific evidence has been presented that supports, therapeutic capabilities of camel’s urine which exhibited a potential antibacterial activity against the tested microorganisms and could be a potential source of new antimicrobial agents.
{"title":"Peculiar Therapeutic Property of Camel’s (Camelus dromedarius) Urine Against Multidrug Resistant Bacteria","authors":"V. Bhardwaj","doi":"10.31579/2693-4779/089","DOIUrl":"https://doi.org/10.31579/2693-4779/089","url":null,"abstract":"The remedial use of camel urine has been known for centuries, with evidence of its use for curative purposes found in early folklore. It has been used to cure different diseases; however, the significant therapeutic benefits of urine have yet to undergo rigorous scientific evaluation. The exploration of the use of camel urine is of great interest to determine their efficacy in pharmaceutical industry. This study investigated the effect of camel’s urine against five human pathogenic bacteria, to determine their efficacy against multidrug resistant microbes. The probe was done by agar well diffusion method. Multidrug resistant (MDR) strains of Bacillus subtilis (ATCC 6633), E. coli (ATCC 8739), Salmonella enterica (ATCC 14028), Staphylococcus aureus (ATCC 6538), Pseudomonas aeruginosa (ATCC 27853) were used in the study. Ciprofloxacin was used as standard. Maximum zone of inhibition was observed with Salmonella enterica which is 33 ± 0.2 mm. Additionally, Multidrug resistant (MDR) strains of E. coli, Pseudomonas aeruginosa and Staphylococcus aureus was strongly inhibited by camel’s urine. Moreover, MDR strains of Bacillus subtilis, also shows inhibition. The potency shown by camel’s urine for therapeutic action, recommends their use against multidrug resistant microorganisms. In this research work, scientific evidence has been presented that supports, therapeutic capabilities of camel’s urine which exhibited a potential antibacterial activity against the tested microorganisms and could be a potential source of new antimicrobial agents.","PeriodicalId":8525,"journal":{"name":"Applied Clinical Research, Clinical Trials and Regulatory Affairs","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83349735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Hesamirostami, Sanli Hesamirostami, Alireza Sanei Motlagh
COVID-19 can cause different catastrophic events and mortalities. Therefore, burn hospitals strategies changed during regional peak of COVID-19 pandemic in the world. Some outpatient strategies were introduced to minimize the contact with infected patients. However, admission strategies were based on the severity of COVID-19 symptoms and also severity of burn injuries. The policy for admission to give inpatient care relates to history, symptoms and COVID-19 PCR results. If all the mentioned criteria were negative, the burn patient was admitted to GREEN area or ward. If the patient was suspected or positive for COVID-19, then would be admitted to RED area or ward. Given that some patients may be carriers without specific symptoms, considering a YELLOW area or ward seems logical for these groups. In GREEN areas one care giver for each adult and two care givers for each pediatric patient were allowed. For all care givers wearing medical masks were obligatory. All patients, care givers and staffs were under constant surveillance for fever and other symptoms. In RED areas no visitors were allowed and for each patient one nurse was assigned in BICU. All elective surgeries were stopped and other procedures were divided to emergency and semi-emergency. Strategies for facing COVID-19 surges especially new variants need to continuously evolve. Changing of infectivity rate, manifestations, resistance to different vaccine and duration of viral shedding necessitate modification of principles according to data collected from involving countries.
{"title":"A Mini-review about Concomitant Burn and COVID-19","authors":"M. Hesamirostami, Sanli Hesamirostami, Alireza Sanei Motlagh","doi":"10.31579/2693-4779/094","DOIUrl":"https://doi.org/10.31579/2693-4779/094","url":null,"abstract":"COVID-19 can cause different catastrophic events and mortalities. Therefore, burn hospitals strategies changed during regional peak of COVID-19 pandemic in the world. Some outpatient strategies were introduced to minimize the contact with infected patients. However, admission strategies were based on the severity of COVID-19 symptoms and also severity of burn injuries. The policy for admission to give inpatient care relates to history, symptoms and COVID-19 PCR results. If all the mentioned criteria were negative, the burn patient was admitted to GREEN area or ward. If the patient was suspected or positive for COVID-19, then would be admitted to RED area or ward. Given that some patients may be carriers without specific symptoms, considering a YELLOW area or ward seems logical for these groups. In GREEN areas one care giver for each adult and two care givers for each pediatric patient were allowed. For all care givers wearing medical masks were obligatory. All patients, care givers and staffs were under constant surveillance for fever and other symptoms. In RED areas no visitors were allowed and for each patient one nurse was assigned in BICU. All elective surgeries were stopped and other procedures were divided to emergency and semi-emergency. Strategies for facing COVID-19 surges especially new variants need to continuously evolve. Changing of infectivity rate, manifestations, resistance to different vaccine and duration of viral shedding necessitate modification of principles according to data collected from involving countries.","PeriodicalId":8525,"journal":{"name":"Applied Clinical Research, Clinical Trials and Regulatory Affairs","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75317263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Staphylococcus aureus infection is a rather insidious disease. If tests have shown that Staphylococcus aureus is found on the skin, intestines, ears or nasopharynx, Treatment with pharmaceutical drugs extracted from medicinal plants can be a way to get rid of infection. Plants are considered the greatest source to obtain new antimicrobials. The present study aimed at evaluating the in vitro antimicrobial activity of methanolic extracts of Artemisia Judaica plant against Staphylococcus aureus Sp. and others pathogenic bacteria, these bacteria are commonly found in hospital-acquired infections. The methanolic extract of Artemisia Judaica effective against the isolates microorganisms, S. aureus, E. coli, P. aeruginosa, The diameter of zone of inhibition was found to be in the range of 14 – 30 mm against various bacterial strains tested, with maximum diameter against bacteria (S. aureus, 30 mm). The methanolic extract of Artemisia Judaica presented the highest anti-staphylococcus aureus activity and was effective against others bacterial strains tested.
{"title":"A Study of active medicinal plant (Artemisia Judaica) against Staphylococcus aureus","authors":"Elmanakhly Mohammed Emam, Anna I. Marakhova","doi":"10.31579/2693-4779/092","DOIUrl":"https://doi.org/10.31579/2693-4779/092","url":null,"abstract":"Staphylococcus aureus infection is a rather insidious disease. If tests have shown that Staphylococcus aureus is found on the skin, intestines, ears or nasopharynx, Treatment with pharmaceutical drugs extracted from medicinal plants can be a way to get rid of infection. Plants are considered the greatest source to obtain new antimicrobials. The present study aimed at evaluating the in vitro antimicrobial activity of methanolic extracts of Artemisia Judaica plant against Staphylococcus aureus Sp. and others pathogenic bacteria, these bacteria are commonly found in hospital-acquired infections. The methanolic extract of Artemisia Judaica effective against the isolates microorganisms, S. aureus, E. coli, P. aeruginosa, The diameter of zone of inhibition was found to be in the range of 14 – 30 mm against various bacterial strains tested, with maximum diameter against bacteria (S. aureus, 30 mm). The methanolic extract of Artemisia Judaica presented the highest anti-staphylococcus aureus activity and was effective against others bacterial strains tested.","PeriodicalId":8525,"journal":{"name":"Applied Clinical Research, Clinical Trials and Regulatory Affairs","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91024226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Because of the primary involvement of the respiratory system, chest computed tomography (CT) is strongly recommended in suspected COVID-19 cases, for both initial evaluation and follow-up [1]. At least seven scoring systems using chest CT have been proposed to quantify lung involvement in COVID-19 which are summarized in table 1 [1-10] and we use the term CT severity score (CTSS) to refer to them with numbers 1-7 to refer to a specific scoring system.
{"title":"Making the best use of CT Quantification Scores in Management of COVID-19 Patients","authors":"Alireza Almasi Nokiani","doi":"10.31579/2693-4779/091","DOIUrl":"https://doi.org/10.31579/2693-4779/091","url":null,"abstract":"Because of the primary involvement of the respiratory system, chest computed tomography (CT) is strongly recommended in suspected COVID-19 cases, for both initial evaluation and follow-up [1]. At least seven scoring systems using chest CT have been proposed to quantify lung involvement in COVID-19 which are summarized in table 1 [1-10] and we use the term CT severity score (CTSS) to refer to them with numbers 1-7 to refer to a specific scoring system.","PeriodicalId":8525,"journal":{"name":"Applied Clinical Research, Clinical Trials and Regulatory Affairs","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82746030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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