Pub Date : 2021-01-01DOI: 10.31024/ajpp.2021.7.4.5
Diksha Aghor,, S. Parameswaran
{"title":"Overview of migraine and novel approach in its treatment","authors":"Diksha Aghor,, S. Parameswaran","doi":"10.31024/ajpp.2021.7.4.5","DOIUrl":"https://doi.org/10.31024/ajpp.2021.7.4.5","url":null,"abstract":"","PeriodicalId":8538,"journal":{"name":"Asian Journal of Pharmacy and Pharmacology","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89403881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.31024/AJPP.2021.7.1.6
S KunduSmita, D. G. Rana
{"title":"Therapeutic role and importance of gut microbiota in brain and related disorder: A review","authors":"S KunduSmita, D. G. Rana","doi":"10.31024/AJPP.2021.7.1.6","DOIUrl":"https://doi.org/10.31024/AJPP.2021.7.1.6","url":null,"abstract":"","PeriodicalId":8538,"journal":{"name":"Asian Journal of Pharmacy and Pharmacology","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79740640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.31024/ajpp.2021.7.5.4
P. Dabadi, C. Mangannavar, M. Shalavadi
Traditional herbal medicines are relatively safer than synthetic or chemically developed drugs. The traditional medicinal performance is very precious for the object that comes from thousands of years of experimental and blunder. Plant-based traditional knowledge has become an organized tool in the exploration for new sources of drugs and innovative chemical entity thus producing the basis of recent medicine and therapeutics (Raji et al, 2014). According to the World Health Organization, about 80% of the world's rural population currently relies on medicinal plants as their complementary or alternative source of health care improved efficacy (Chan, 2003). Nowadays the use of herbal plants is growing all over the world for the treatment of various diseases, due to their potential antioxidant activities. It is generally understood that oxidative stress generates a large number of reactive oxygen species / free radicals, which play a significant role in the pathophysiology of many diseases, including inflammatory disorders. Oxidative stress is produced when there is inequality among the formation of reactive oxygen species (ROS) and reactive nitrogen species (RNS) and the number of cellular antioxidants that can lead to multiple reactions causing damage or death of cells (Shebis et al., 2013). An
{"title":"Preliminary phytochemical screening, quantitative estimation and in-vitro antioxidant activity of Anamirta cocculus (L) fruits","authors":"P. Dabadi, C. Mangannavar, M. Shalavadi","doi":"10.31024/ajpp.2021.7.5.4","DOIUrl":"https://doi.org/10.31024/ajpp.2021.7.5.4","url":null,"abstract":"Traditional herbal medicines are relatively safer than synthetic or chemically developed drugs. The traditional medicinal performance is very precious for the object that comes from thousands of years of experimental and blunder. Plant-based traditional knowledge has become an organized tool in the exploration for new sources of drugs and innovative chemical entity thus producing the basis of recent medicine and therapeutics (Raji et al, 2014). According to the World Health Organization, about 80% of the world's rural population currently relies on medicinal plants as their complementary or alternative source of health care improved efficacy (Chan, 2003). Nowadays the use of herbal plants is growing all over the world for the treatment of various diseases, due to their potential antioxidant activities. It is generally understood that oxidative stress generates a large number of reactive oxygen species / free radicals, which play a significant role in the pathophysiology of many diseases, including inflammatory disorders. Oxidative stress is produced when there is inequality among the formation of reactive oxygen species (ROS) and reactive nitrogen species (RNS) and the number of cellular antioxidants that can lead to multiple reactions causing damage or death of cells (Shebis et al., 2013). An","PeriodicalId":8538,"journal":{"name":"Asian Journal of Pharmacy and Pharmacology","volume":"63 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73066634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.31024/ajpp.2021.7.4.4
Rahat Kumar, Narinder P. Singh, Jaswinder Singh, V. Bhandari
COVID-19 infection was emerged in December 2019, when a group of patients presented with pneumonia of unknown cause in Wuhan, China. COVID-19 is caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARSCoV-2 infection may be asymptomatic or it may cause a wide spectrum of symptoms, such as mild symptoms of upper respiratory tract infection and life-threatening sepsis. Coronaviruses (CoV) are a family of viruses called Coronaviridae These viruses are zoonotic, that is, they are . transmitted between animals and humans. The SARS-CoV-2 virus belongs to the family of RNA viruses and the genomic sequence ranges from 125 nm or 0.125μm. Corona virus is a single stranded, enveloped RNA in shape having a positive sense RNA genome also known as (+ssRNA) with a 5′-cap structure and 3′-poly-A tail (Chen et al., 2019). There are four essential structural proteins required to regulate the function and viral structure of the virus; which are (E) the envelope protein, (M) the membrane protein, (S) the spike protein, and (N) the nucleocapsid protein (Schoeman et al., 2019). The genome sequencing based research revealed that the coronavirus is a beta-coronavirus belonging to the subtypes Pharmacovigilance of ChAdOx1 nCoV-19 (COVISHIELD) Vaccine after first and second dose in volunteers in Punjab, India Rahat Kumar , Narinder Singh, Jaswinder Singh, Vikram Bhandari *
{"title":"Pharmacovigilance of ChAdOx1 nCoV-19 (COVISHIELD) Vaccine after first and second dose in volunteers in Punjab, India","authors":"Rahat Kumar, Narinder P. Singh, Jaswinder Singh, V. Bhandari","doi":"10.31024/ajpp.2021.7.4.4","DOIUrl":"https://doi.org/10.31024/ajpp.2021.7.4.4","url":null,"abstract":"COVID-19 infection was emerged in December 2019, when a group of patients presented with pneumonia of unknown cause in Wuhan, China. COVID-19 is caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARSCoV-2 infection may be asymptomatic or it may cause a wide spectrum of symptoms, such as mild symptoms of upper respiratory tract infection and life-threatening sepsis. Coronaviruses (CoV) are a family of viruses called Coronaviridae These viruses are zoonotic, that is, they are . transmitted between animals and humans. The SARS-CoV-2 virus belongs to the family of RNA viruses and the genomic sequence ranges from 125 nm or 0.125μm. Corona virus is a single stranded, enveloped RNA in shape having a positive sense RNA genome also known as (+ssRNA) with a 5′-cap structure and 3′-poly-A tail (Chen et al., 2019). There are four essential structural proteins required to regulate the function and viral structure of the virus; which are (E) the envelope protein, (M) the membrane protein, (S) the spike protein, and (N) the nucleocapsid protein (Schoeman et al., 2019). The genome sequencing based research revealed that the coronavirus is a beta-coronavirus belonging to the subtypes Pharmacovigilance of ChAdOx1 nCoV-19 (COVISHIELD) Vaccine after first and second dose in volunteers in Punjab, India Rahat Kumar , Narinder Singh, Jaswinder Singh, Vikram Bhandari *","PeriodicalId":8538,"journal":{"name":"Asian Journal of Pharmacy and Pharmacology","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75515204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.31024/ajpp.2021.7.3.4
Sakshi Singh Chouhan, N. Farooqui, D. Mishra
{"title":"Formulation and evaluation of liposomal loaded nail lacquer containing luliconazole an antifungal drug","authors":"Sakshi Singh Chouhan, N. Farooqui, D. Mishra","doi":"10.31024/ajpp.2021.7.3.4","DOIUrl":"https://doi.org/10.31024/ajpp.2021.7.3.4","url":null,"abstract":"","PeriodicalId":8538,"journal":{"name":"Asian Journal of Pharmacy and Pharmacology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74419905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.31024/ajpp.2021.7.6.1
B. Michel, K. Fidèle, O. C. Okou, K. Koffi, T. Flavien
{"title":"Effects of aqueous extract of Albizia glaberrima on the reproductive system of female adult Wistar albino rats","authors":"B. Michel, K. Fidèle, O. C. Okou, K. Koffi, T. Flavien","doi":"10.31024/ajpp.2021.7.6.1","DOIUrl":"https://doi.org/10.31024/ajpp.2021.7.6.1","url":null,"abstract":"","PeriodicalId":8538,"journal":{"name":"Asian Journal of Pharmacy and Pharmacology","volume":"59 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73321713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.31024/ajpp.2021.7.2.3
S. Mallurwar, V. Nakra, M. Bhat
{"title":"Clinical perspectives of Janus Kinase Inhibitors: A review","authors":"S. Mallurwar, V. Nakra, M. Bhat","doi":"10.31024/ajpp.2021.7.2.3","DOIUrl":"https://doi.org/10.31024/ajpp.2021.7.2.3","url":null,"abstract":"","PeriodicalId":8538,"journal":{"name":"Asian Journal of Pharmacy and Pharmacology","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80017864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.31024/ajpp.2021.7.5.3
Md. Jannatul Islam Polash,, R. Agarwala, Khadija Tul Simran, Thashina Tasnim Tisha, A. Sarkar
The earth is on the edge of reverting to the 'pre-antibiotics era' because of developing resistance to life-saving antimicrobial medicines, with significant consequences for both individual and public health (Hoque et al., 2020). “Antibiotic resistance is one of the major public health issues, particularly in developing countries where relatively easy access and higher consumption of medicines have resulted in a disproportionately higher incidence of inappropriate antibiotic use and higher levels of resistance compared to developed countries” (Kumar et al., 2013). The widespread usage of antibiotics both therapeutically and nontherapeutically has led to the development and dissemination of microbial resistance, and resistance genes are the determinants both in the clinical and non-clinical settings (Igbinosa and Odjadjare, 2015). The most prominent causes of antibiotic resistance are a constant inability to enhance or discover new antibiotics, as well as the indiscriminate use of antibiotics (Aslam et al., 2018). AMR poses a substantial risk of mortality and economic instability worldwide. “In contrast, the developing countries are more affected because of the widespread misuse of antibiotics, nonhuman antibiotic use, low quality of drugs, inadequate surveillance, and factors associated with individual and national poverty (poor healthcare standards, malnutrition, chronic and recurring infections, unaffordability of efficient and expensive medications)” (Ayukekbong et al., 2017; Sosa et al., 2010).
由于对挽救生命的抗微生物药物产生耐药性，地球正处于回到“前抗生素时代”的边缘，这对个人和公共卫生都产生了重大影响(Hoque等人，2020年)。“抗生素耐药性是主要的公共卫生问题之一，特别是在发展中国家，与发达国家相比，相对容易获得和较高的药物消费量导致不适当使用抗生素的发生率和耐药性水平过高”(Kumar等人，2013年)。抗生素在治疗和非治疗方面的广泛使用导致了微生物耐药性的发展和传播，耐药基因是临床和非临床环境中的决定因素(Igbinosa和Odjadjare, 2015)。抗生素耐药性最突出的原因是不断无法增强或发现新的抗生素，以及滥用抗生素(Aslam等人，2018)。抗菌素耐药性在世界范围内造成死亡和经济不稳定的重大风险。“相比之下，发展中国家受到的影响更大，因为抗生素的广泛滥用、非人类抗生素的使用、药物质量低、监测不足，以及与个人和国家贫困相关的因素(卫生保健标准差、营养不良、慢性和反复感染、负担不起有效和昂贵的药物)”(Ayukekbong等人，2017;Sosa et al.， 2010)。
{"title":"Antibiotic resistance in Bangladesh: A current epilogue, and a systematic review","authors":"Md. Jannatul Islam Polash,, R. Agarwala, Khadija Tul Simran, Thashina Tasnim Tisha, A. Sarkar","doi":"10.31024/ajpp.2021.7.5.3","DOIUrl":"https://doi.org/10.31024/ajpp.2021.7.5.3","url":null,"abstract":"The earth is on the edge of reverting to the 'pre-antibiotics era' because of developing resistance to life-saving antimicrobial medicines, with significant consequences for both individual and public health (Hoque et al., 2020). “Antibiotic resistance is one of the major public health issues, particularly in developing countries where relatively easy access and higher consumption of medicines have resulted in a disproportionately higher incidence of inappropriate antibiotic use and higher levels of resistance compared to developed countries” (Kumar et al., 2013). The widespread usage of antibiotics both therapeutically and nontherapeutically has led to the development and dissemination of microbial resistance, and resistance genes are the determinants both in the clinical and non-clinical settings (Igbinosa and Odjadjare, 2015). The most prominent causes of antibiotic resistance are a constant inability to enhance or discover new antibiotics, as well as the indiscriminate use of antibiotics (Aslam et al., 2018). AMR poses a substantial risk of mortality and economic instability worldwide. “In contrast, the developing countries are more affected because of the widespread misuse of antibiotics, nonhuman antibiotic use, low quality of drugs, inadequate surveillance, and factors associated with individual and national poverty (poor healthcare standards, malnutrition, chronic and recurring infections, unaffordability of efficient and expensive medications)” (Ayukekbong et al., 2017; Sosa et al., 2010).","PeriodicalId":8538,"journal":{"name":"Asian Journal of Pharmacy and Pharmacology","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80217642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.31024/ajpp.2021.7.3.2
K. Jeevika, R. A. Sobiya, T. Indhumathi, S. Kathiravan
{"title":"Feasibility of nano-scaffold for Covid-19 infected lung tissue regeneration: A review","authors":"K. Jeevika, R. A. Sobiya, T. Indhumathi, S. Kathiravan","doi":"10.31024/ajpp.2021.7.3.2","DOIUrl":"https://doi.org/10.31024/ajpp.2021.7.3.2","url":null,"abstract":"","PeriodicalId":8538,"journal":{"name":"Asian Journal of Pharmacy and Pharmacology","volume":"210 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74958091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.31024/ajpp.2021.7.5.1
A. M., M. Sarkhil, M. Fayazuddin, F. Ahmad
{"title":"Peripheral analgesic activity of Moringa oleifera seeds - An experimental study","authors":"A. M., M. Sarkhil, M. Fayazuddin, F. Ahmad","doi":"10.31024/ajpp.2021.7.5.1","DOIUrl":"https://doi.org/10.31024/ajpp.2021.7.5.1","url":null,"abstract":"","PeriodicalId":8538,"journal":{"name":"Asian Journal of Pharmacy and Pharmacology","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80414797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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