Pub Date : 2022-01-01DOI: 10.31024/ajpp.2022.8.6.3
Sateesha S.B., Hirday Narayan Sah, Rajamma A.J.
{"title":"Development of reconstitutable nano-liposome of Ferrous Ascorbate for prophylaxis and treatment of iron deficiency anemia","authors":"Sateesha S.B., Hirday Narayan Sah, Rajamma A.J.","doi":"10.31024/ajpp.2022.8.6.3","DOIUrl":"https://doi.org/10.31024/ajpp.2022.8.6.3","url":null,"abstract":"","PeriodicalId":8538,"journal":{"name":"Asian Journal of Pharmacy and Pharmacology","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88238096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.31024/ajpp.2022.8.3.2
P. Mumthaj, N. P
{"title":"Evaluation of Anogeissus latifolia Roxb on complete freund’s adjuvant induced arthritis in albino rats","authors":"P. Mumthaj, N. P","doi":"10.31024/ajpp.2022.8.3.2","DOIUrl":"https://doi.org/10.31024/ajpp.2022.8.3.2","url":null,"abstract":"","PeriodicalId":8538,"journal":{"name":"Asian Journal of Pharmacy and Pharmacology","volume":"85 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78182537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.31024/ajpp.2022.8.5.2
Puneeth G.K, Johncy Natasha, S. N, Kush Nimron
{"title":"A Retrospective study on Adverse Drug Reactions Monitoring and Reporting in a quaternary care super speciality hospital in Karnataka","authors":"Puneeth G.K, Johncy Natasha, S. N, Kush Nimron","doi":"10.31024/ajpp.2022.8.5.2","DOIUrl":"https://doi.org/10.31024/ajpp.2022.8.5.2","url":null,"abstract":"","PeriodicalId":8538,"journal":{"name":"Asian Journal of Pharmacy and Pharmacology","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85233030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.31024/ajpp.2022.8.4.4
A. M. Krupanidhi, P. Dabadi, Chandana M., Mythree M.V., Pooja H. S., Pooja J. U., Sushma S.,, Sushruta K. H.
{"title":"A brief review on Pharmacological properties of Abutilon indicum roots","authors":"A. M. Krupanidhi, P. Dabadi, Chandana M., Mythree M.V., Pooja H. S., Pooja J. U., Sushma S.,, Sushruta K. H.","doi":"10.31024/ajpp.2022.8.4.4","DOIUrl":"https://doi.org/10.31024/ajpp.2022.8.4.4","url":null,"abstract":"","PeriodicalId":8538,"journal":{"name":"Asian Journal of Pharmacy and Pharmacology","volume":"391 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80750133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Transmembrane passage of Sulfamethoxazole/Trimethoprim in combination with leaves extracts of Pseudocedrela kotschyi and Crossopteryx febrifuga","authors":"Thierry Lenoir Ayoman Djadji, É. Balayssac, Armelle Sandrine Aka-Any Grah, Nounaferitien Awa Silue, Gbongué Eric Tia, Sylvain Landry Kouakoa, Gisèle N'doua Siranst-Kouakou","doi":"10.31024/ajpp.2022.8.4.1","DOIUrl":"https://doi.org/10.31024/ajpp.2022.8.4.1","url":null,"abstract":"","PeriodicalId":8538,"journal":{"name":"Asian Journal of Pharmacy and Pharmacology","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73338220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.31024/ajpp.2022.8.2.3
R. G. Raj, J. Benny, A. Siddiq, Shethal Saji, S. P
{"title":"A comparative assessment of antidiabetic drug usage and related pharmaceutical care issues between Geriatric and non-Geriatric population in teaching hospital","authors":"R. G. Raj, J. Benny, A. Siddiq, Shethal Saji, S. P","doi":"10.31024/ajpp.2022.8.2.3","DOIUrl":"https://doi.org/10.31024/ajpp.2022.8.2.3","url":null,"abstract":"","PeriodicalId":8538,"journal":{"name":"Asian Journal of Pharmacy and Pharmacology","volume":"2002 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88369853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.31024/ajpp.2022.8.3.5
Geetha Rani Valaparla, Gutta Vishnu Sai, D. Kumar
Objective: Obesity is one of the world's leading problems, which is major cause of Cardiovascular Diseases. During COVID - 19 pandemic many young children and all age group people are getting challenged by obesity due stagnant life style. To treat such life threatening disorder natural remedies acquire prior position, Plant produce a good deal of secondary metabolites which have a benefited mankind in various ways, including treatment of diseases The present research work was focused on developing a natural remedy using an ancient plant with number of Tamarindus indica, proven activities in Traditional medicine. In the literature survey, it was found that Materials and Methods: flavonoids, sterols, tannins and alkaloids shown promising effects to tackle obesity by various mechanisms, Tamarindus indica has shown the presence of saponins, flavonoids, glycosides, amino acids, alkaloids. With the above evidence, this plant has been selected for screening of its antiobesity activity against high fat diet induced obesity in mice. Studies were conducted using aqueous extract of leaves (AETI) on high fat diet (butter) Tamarindus indica induced model of hyperlipidemia in mice. During 21 days time period AETI low and high Results and Discussion: doses were induced to respective animal groups along with butter where Atorvastatin has been taken as standard drug. Butter enhanced the Cholesterol and triglyceride, LDL levels. At the end of 21 days blood samples were collected from the animal through retroperitoneal route. Biochemical parameters of AETI have been revealed its antiobesity activity. high fat antiobesity, Atorvastatin
{"title":"Assessment of anti-obesity activity of Tamarindus leaves on butter induced hyperlipidemia in mice","authors":"Geetha Rani Valaparla, Gutta Vishnu Sai, D. Kumar","doi":"10.31024/ajpp.2022.8.3.5","DOIUrl":"https://doi.org/10.31024/ajpp.2022.8.3.5","url":null,"abstract":"Objective: Obesity is one of the world's leading problems, which is major cause of Cardiovascular Diseases. During COVID - 19 pandemic many young children and all age group people are getting challenged by obesity due stagnant life style. To treat such life threatening disorder natural remedies acquire prior position, Plant produce a good deal of secondary metabolites which have a benefited mankind in various ways, including treatment of diseases The present research work was focused on developing a natural remedy using an ancient plant with number of Tamarindus indica, proven activities in Traditional medicine. In the literature survey, it was found that Materials and Methods: flavonoids, sterols, tannins and alkaloids shown promising effects to tackle obesity by various mechanisms, Tamarindus indica has shown the presence of saponins, flavonoids, glycosides, amino acids, alkaloids. With the above evidence, this plant has been selected for screening of its antiobesity activity against high fat diet induced obesity in mice. Studies were conducted using aqueous extract of leaves (AETI) on high fat diet (butter) Tamarindus indica induced model of hyperlipidemia in mice. During 21 days time period AETI low and high Results and Discussion: doses were induced to respective animal groups along with butter where Atorvastatin has been taken as standard drug. Butter enhanced the Cholesterol and triglyceride, LDL levels. At the end of 21 days blood samples were collected from the animal through retroperitoneal route. Biochemical parameters of AETI have been revealed its antiobesity activity. high fat antiobesity, Atorvastatin","PeriodicalId":8538,"journal":{"name":"Asian Journal of Pharmacy and Pharmacology","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80462275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.31024/ajpp.2022.8.3.4
J. Nfongeh, Dauda Anoh Hashimu, D. D. Odonye͙͙͙͙͙, Adamu Abisabo, Aminu Kazeem Fauzeeyah, A. Kabiru
Objective: Non-sterile pharmaceutical products are usually subjected to unrestricted handling and are therefore potentially susceptible to postproduction contamination by microorganisms from both handlers and the environment. This study was carried out to determine the microbial quality of some commonly administered non-sterile drug types from hawkers and pharmacy outlets within Lafia Metropolis, Nigeria. : A total of 240 samples Material and methods (80 samples each of tablets, syrups and ointments) were purchased from pharmacies and hawkers' outlets and the microbial load determined using the W.H.O Pharmacopoeia and serological methods. From Results and conclusion: this study, the mean Total Aerobic Bacterial Counts (TABC) and the Mean Total Yeast and Mold Counts (TYMC) had values higher than the W.H.O recommended levels for some syrups and tablets from both pharmacy and hawkers' outlets. The difference in the values among the various outlets and between the drug types were statistically significant at p<0.05. Results of immunoassay indicated that was isolated from 23/120 (19.17%) hawkers' drugs among E. coli which 1/23 (4.35%) was the O157:H7serotype. Similarly, 17/120 (14.17%) hawkers' drugs had Staphylococcus aureus among which 8/17(47.06%) and 6/17(35.27%) were and serotypes respectively while 3/17(17.65%) had no cp5 cp8 capsular antigen ( ). These values were significantly higher (p<0.05) than those obtained from pharmacy outlets. The cp-microbial qualities of most of the pharmacy products were in accordance with International Pharmacopoeia while some, especially the tablets and syrups from hawkers, exceeded the recommended acceptance limit and might be of health risks to consumers.
{"title":"Microbial load and O157:H7, cp5, cp8 Serotypes assessment of some non-sterile pharmaceutical drug types sold at major outlets in Lafia, Nigeria","authors":"J. Nfongeh, Dauda Anoh Hashimu, D. D. Odonye͙͙͙͙͙, Adamu Abisabo, Aminu Kazeem Fauzeeyah, A. Kabiru","doi":"10.31024/ajpp.2022.8.3.4","DOIUrl":"https://doi.org/10.31024/ajpp.2022.8.3.4","url":null,"abstract":"Objective: Non-sterile pharmaceutical products are usually subjected to unrestricted handling and are therefore potentially susceptible to postproduction contamination by microorganisms from both handlers and the environment. This study was carried out to determine the microbial quality of some commonly administered non-sterile drug types from hawkers and pharmacy outlets within Lafia Metropolis, Nigeria. : A total of 240 samples Material and methods (80 samples each of tablets, syrups and ointments) were purchased from pharmacies and hawkers' outlets and the microbial load determined using the W.H.O Pharmacopoeia and serological methods. From Results and conclusion: this study, the mean Total Aerobic Bacterial Counts (TABC) and the Mean Total Yeast and Mold Counts (TYMC) had values higher than the W.H.O recommended levels for some syrups and tablets from both pharmacy and hawkers' outlets. The difference in the values among the various outlets and between the drug types were statistically significant at p<0.05. Results of immunoassay indicated that was isolated from 23/120 (19.17%) hawkers' drugs among E. coli which 1/23 (4.35%) was the O157:H7serotype. Similarly, 17/120 (14.17%) hawkers' drugs had Staphylococcus aureus among which 8/17(47.06%) and 6/17(35.27%) were and serotypes respectively while 3/17(17.65%) had no cp5 cp8 capsular antigen ( ). These values were significantly higher (p<0.05) than those obtained from pharmacy outlets. The cp-microbial qualities of most of the pharmacy products were in accordance with International Pharmacopoeia while some, especially the tablets and syrups from hawkers, exceeded the recommended acceptance limit and might be of health risks to consumers.","PeriodicalId":8538,"journal":{"name":"Asian Journal of Pharmacy and Pharmacology","volume":"83 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75788404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.31024/ajpp.2022.8.6.4
A. Shukla, M. Nireekshan Kumar, M. Sharma, S. K. Dev, Rahul Maurya
{"title":"Usnic acid: A promising bioactive agent for wound healing","authors":"A. Shukla, M. Nireekshan Kumar, M. Sharma, S. K. Dev, Rahul Maurya","doi":"10.31024/ajpp.2022.8.6.4","DOIUrl":"https://doi.org/10.31024/ajpp.2022.8.6.4","url":null,"abstract":"","PeriodicalId":8538,"journal":{"name":"Asian Journal of Pharmacy and Pharmacology","volume":"138 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83123713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.31024/ajpp.2022.8.3.1
V. Nikam, S. Suryawanshi, Jyoti Khapare
The protein and Peptide delivery system is the Novel drug Delivery System. Proteins and peptides are the most abundant components of living cells. There are those that act as enzymes, hormones, structural element and immunoglobulin. Twenty different naturally occurring amino acids combine with each other through peptide bonds and form polymers targeting peptides and proteins. Although the difference between peptides and proteins in peptide contains less than 20 amino acids, they have a molecular weight of less than 5000, while the protein has 50 amino acids or more and its molecular weight is above this value. Most pharmaceutical proteins and peptides are absorbed by IM, IV and the Subcutaneous route of Absorption, but the oral route is better absorbed by protein compared to another. Various problems associated with protein and peptide drug administration are needed to overcome various drug regimens. A few ways available to increase pharmacokinetic and pharmacodynamics properties are chemical modification, construction vehicles, mucoadhesive polymeric system, use of enzyme inhibitors, absorption enhancers, infiltration enhancers etc. Current review defines structure, protein separation, need, benefits, protein function and peptide drug delivery system.
{"title":"Protein and peptide drug delivery system: A brief review","authors":"V. Nikam, S. Suryawanshi, Jyoti Khapare","doi":"10.31024/ajpp.2022.8.3.1","DOIUrl":"https://doi.org/10.31024/ajpp.2022.8.3.1","url":null,"abstract":"The protein and Peptide delivery system is the Novel drug Delivery System. Proteins and peptides are the most abundant components of living cells. There are those that act as enzymes, hormones, structural element and immunoglobulin. Twenty different naturally occurring amino acids combine with each other through peptide bonds and form polymers targeting peptides and proteins. Although the difference between peptides and proteins in peptide contains less than 20 amino acids, they have a molecular weight of less than 5000, while the protein has 50 amino acids or more and its molecular weight is above this value. Most pharmaceutical proteins and peptides are absorbed by IM, IV and the Subcutaneous route of Absorption, but the oral route is better absorbed by protein compared to another. Various problems associated with protein and peptide drug administration are needed to overcome various drug regimens. A few ways available to increase pharmacokinetic and pharmacodynamics properties are chemical modification, construction vehicles, mucoadhesive polymeric system, use of enzyme inhibitors, absorption enhancers, infiltration enhancers etc. Current review defines structure, protein separation, need, benefits, protein function and peptide drug delivery system.","PeriodicalId":8538,"journal":{"name":"Asian Journal of Pharmacy and Pharmacology","volume":"73 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90325224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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