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Asian Journal of Pharmacy and Pharmacology最新文献

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Investigations on Corchorus aestuans extracts for ulcerative colitis in experimental animals 山茱萸提取物治疗实验性动物溃疡性结肠炎的研究
Pub Date : 2022-01-01 DOI: 10.31024/ajpp.2022.8.5.5
R. Ranjan, M. Kori, S. Lodhi
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引用次数: 0
Usnic acid: A promising bioactive agent for wound healing Usnic酸:一种很有前途的伤口愈合生物活性剂
Pub Date : 2022-01-01 DOI: 10.31024/ajpp.2022.8.6.4
A. Shukla, M. Nireekshan Kumar, M. Sharma, S. K. Dev, Rahul Maurya
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引用次数: 0
Protein and peptide drug delivery system: A brief review 蛋白质和多肽药物传递系统:综述
Pub Date : 2022-01-01 DOI: 10.31024/ajpp.2022.8.3.1
V. Nikam, S. Suryawanshi, Jyoti Khapare
The protein and Peptide delivery system is the Novel drug Delivery System. Proteins and peptides are the most abundant components of living cells. There are those that act as enzymes, hormones, structural element and immunoglobulin. Twenty different naturally occurring amino acids combine with each other through peptide bonds and form polymers targeting peptides and proteins. Although the difference between peptides and proteins in peptide contains less than 20 amino acids, they have a molecular weight of less than 5000, while the protein has 50 amino acids or more and its molecular weight is above this value. Most pharmaceutical proteins and peptides are absorbed by IM, IV and the Subcutaneous route of Absorption, but the oral route is better absorbed by protein compared to another. Various problems associated with protein and peptide drug administration are needed to overcome various drug regimens. A few ways available to increase pharmacokinetic and pharmacodynamics properties are chemical modification, construction vehicles, mucoadhesive polymeric system, use of enzyme inhibitors, absorption enhancers, infiltration enhancers etc. Current review defines structure, protein separation, need, benefits, protein function and peptide drug delivery system.
蛋白质和肽传递系统是一种新型的药物传递系统。蛋白质和多肽是活细胞中最丰富的成分。它们是酶、激素、结构因子和免疫球蛋白。20种不同的天然氨基酸通过肽键相互结合,形成针对肽和蛋白质的聚合物。虽然多肽与蛋白质之间的差异包含不到20个氨基酸,但它们的分子量小于5000,而蛋白质具有50个或更多的氨基酸且其分子量高于此值。大多数药物蛋白和多肽通过IM、IV和皮下吸收途径吸收,但口服途径比其他途径更容易被蛋白质吸收。与蛋白质和多肽药物管理有关的各种问题需要克服各种药物方案。提高药代动力学和药效学性能的几种方法有化学修饰、施工载体、黏附聚合物体系、使用酶抑制剂、吸收增强剂、渗透增强剂等。本文综述了结构、蛋白质分离、需求、益处、蛋白质功能和多肽给药系统的定义。
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引用次数: 0
Moringa oleifera Lam: A versatile medicinal tree in tropical and subtropical countries 辣木:热带和亚热带国家的一种多功能药用树木
Pub Date : 2022-01-01 DOI: 10.31024/ajpp.2022.8.4.5
P. C. Gupta
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引用次数: 1
Formulation development and evaluation of antidiabetic activity of Aegle marmelos roots 蜜瓜根的配方开发及抗糖尿病活性评价
Pub Date : 2022-01-01 DOI: 10.31024/ajpp.2022.8.5.4
D. Tiwari, Kajal Sharma, Shivani L Goyal, Kaushelendra Mishra, A. Chaturvedi
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引用次数: 0
Evaluation of neuroprotective activity of Calotropis gigantea Linn stem bark on experimentally induced neuro toxicity in various animal models 不同动物模型实验诱导的巨山茶茎皮神经保护作用的评价
Pub Date : 2022-01-01 DOI: 10.31024/ajpp.2022.8.6.1
D. Angadi, Omkarswamy Maradimath, I. Shanmukha, Prashanth K. U.
{"title":"Evaluation of neuroprotective activity of Calotropis gigantea Linn stem bark on experimentally induced neuro toxicity in various animal models","authors":"D. Angadi, Omkarswamy Maradimath, I. Shanmukha, Prashanth K. U.","doi":"10.31024/ajpp.2022.8.6.1","DOIUrl":"https://doi.org/10.31024/ajpp.2022.8.6.1","url":null,"abstract":"","PeriodicalId":8538,"journal":{"name":"Asian Journal of Pharmacy and Pharmacology","volume":"254 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76762805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anti-inflammatory potential of Secamone afzelii extract: A study of Ivorian traditional plant on experimental rats 科特迪瓦传统植物西卡蒙提取物抗炎作用的实验研究
Pub Date : 2022-01-01 DOI: 10.31024/ajpp.2022.8.5.3
K. S. Landry, Yao-Kouassi Philomène Akoua, Koffi Kouamé Jean-Michel, Kimou Anderson Claver, Kouakou-Siransy Gisèle
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引用次数: 0
Effect of aqueous extract of Citrullus lanatus Rind on ethanol-induced hepatotoxicity in rats 瓜皮水提物对乙醇致大鼠肝毒性的影响
Pub Date : 2022-01-01 DOI: 10.31024/ajpp.2022.8.5.1
R. Aishwarya, H. Kumari, R. Padmavathi
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引用次数: 0
Investigations on Ipomoea reniformis seeds for antiulcer potential in rats 梨树种子对大鼠抗溃疡潜能的研究
Pub Date : 2022-01-01 DOI: 10.31024/ajpp.2022.8.6.2
Ankit Jain, S. Lodhi
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引用次数: 0
Formulation and evaluation of effervescent granules of Ranitidine Hydrochloride 盐酸雷尼替丁泡腾剂的研制及评价
Pub Date : 2022-01-01 DOI: 10.31024/ajpp.2022.8.4.3
K. MunirajaLakshmi, P. Keerthana, O. Koushik, G. Himabindhu, T. U. Usha Kiran, G. S. Reddy
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引用次数: 0
期刊
Asian Journal of Pharmacy and Pharmacology
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