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Why policy relevant research still matters for community water fluoridation.
IF 1.9 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-03-03 DOI: 10.1111/adj.13063
T M Nguyen, C Sexton, L Do

Community water fluoridation is one of the most important public health interventions. Despite reliable systematically revised evidence supporting the associated health and economic benefits, its implementation to expand community water fluoridation is variable in Australia. Our editorial provides commentary on the existing evidence, and the gaps in adopting Cochrane review methods, and calls for more policy-relevant research to ensure community water fluoridation remains a priority for all levels of government and civil society actors.

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引用次数: 0
Am I incompetent?
IF 1.9 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-03-03 DOI: 10.1111/adj.13064
I Darby
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引用次数: 0
OSA pathophysiology: a contemporary update.
IF 1.9 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-03-03 DOI: 10.1111/adj.13060
T M Tolbert, I Ayappa, D M Rapoport

Defined as an elevated frequency of obstructive respiratory events in sleep, obstructive sleep apnoea (OSA) is driven by a combination of four pathophysiologic mechanisms: elevated upper airway collapsibility, unstable ventilatory control, impaired upper airway dilator muscle responsiveness and decreased arousal threshold. Established therapies such as continuous positive airway pressure (CPAP) and oral appliance therapy (OAT) work chiefly through targeting elevated collapsibility, which affects the majority of OSA patients. However, many patients respond poorly or do not tolerate these 'anatomic' therapies. The emerging field of 'precision sleep medicine' seeks to determine if novel treatment approaches specifically targeting the other, 'non-anatomic' mechanisms will improve treatment efficacy and acceptance. In this review, we consider the concepts underlying each pathophysiologic mechanism, the predisposing factors, and the potential implications for established and future OSA treatments.

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引用次数: 0
Introduction to dental sleep medicine supplement.
IF 1.9 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-02-27 DOI: 10.1111/adj.13065
I Darby
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引用次数: 0
Oral appliance therapy for snoring and obstructive sleep apnoea: a Practical Guide for Clinical Care.
IF 1.9 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-02-27 DOI: 10.1111/adj.13062
R Balasubramaniam, K McCloy, F R Almeida, P A Cistulli

Obstructive sleep apnoea (OSA) is a disorder associated with multiple cardiovascular, metabolic and neurocognitive comorbidities which impact the health and quality of life of patients. Dentists trained in dental sleep medicine have a significant role as part of a collaborative multidisciplinary team led by specialist sleep physicians in the overall management of OSA. Based on the recommendations of the medical team and the patient's preference, dentists have a pertinent role in the provision of oral appliance (OA) therapy for OSA. This narrative review provides a practical guide for OA therapy for snoring and OSA.

{"title":"Oral appliance therapy for snoring and obstructive sleep apnoea: a Practical Guide for Clinical Care.","authors":"R Balasubramaniam, K McCloy, F R Almeida, P A Cistulli","doi":"10.1111/adj.13062","DOIUrl":"https://doi.org/10.1111/adj.13062","url":null,"abstract":"<p><p>Obstructive sleep apnoea (OSA) is a disorder associated with multiple cardiovascular, metabolic and neurocognitive comorbidities which impact the health and quality of life of patients. Dentists trained in dental sleep medicine have a significant role as part of a collaborative multidisciplinary team led by specialist sleep physicians in the overall management of OSA. Based on the recommendations of the medical team and the patient's preference, dentists have a pertinent role in the provision of oral appliance (OA) therapy for OSA. This narrative review provides a practical guide for OA therapy for snoring and OSA.</p>","PeriodicalId":8593,"journal":{"name":"Australian dental journal","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143514348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ambulatory devices to detect sleep bruxism: a narrative review.
IF 1.9 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-02-20 DOI: 10.1111/adj.13057
C Li, S Yap, A Loh, Y J Yap, O Kujan, R Balasubramaniam

Sleep bruxism is a masticatory muscle activity that occurs during sleep and presents as rhythmic or non-rhythmic activities commonly seen in healthy individuals but might also represent movement or sleep disorders. Given that the clinical presentations of sleep bruxism are relevant to dentistry, the early detection of sleep bruxism is of particular interest to dentists. However, the gold standard for sleep bruxism diagnosis involves polysomnography with audio-visual recording - a resource intensive and mostly inaccessible diagnostic method. As such, ambulatory devices to detect sleep bruxism have the potential to address the limitations of polysomnography. This review of the literature was carried out up until December 2024 on commercially available ambulatory devices in detecting sleep bruxism. Select ambulatory devices appear promising as a preliminary screening tool for sleep bruxism both in clinical practice and for domestic use.

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引用次数: 0
Comparison of the effects of occlusal splint and Botox injections on the amount of mouth opening and chronic pain in individuals with temporomandibular disorders: a systematic review and meta-analysis.
IF 1.9 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-02-14 DOI: 10.1111/adj.13059
Ö İşisağ, H Atasoy, S Yıldız

Objective: This systematic review and meta-analysis study was carried out to compare the effectiveness of occlusal splint (OS) and Botox (BTX) injections in temporomandibular disorders (TMDs).

Material and methods: Irrespective of the starting year, studies were searched for up to 2024 using PubMed, Web of Science, Scopus databases and the Google Scholar search engine. In the study, graded chronic pain scale and maximum mouth opening amount parameters were analysed with Comprehensive Meta-Analysis programme.

Results: Out of 619 studies, only six were included in the meta-analysis. The effect size was 0.293 in favour of BTX in the studies evaluating the maximum mouth-opening (MMO) range. However, the amount of MMO did not show a statistically significant difference between the OS and BTX groups (95% CI - 0.383 to 0.969, P = 0.395, z = -0.850). In the subgroup analyses carried out based on the follow-up periods, it was found that the MMO was statistically significantly higher in the BTX group at the first week and in the OS group at the third month. However, there was no significant difference observed at the first, second, sixth and twelfth month follow-ups (P > 0.05). No significant difference was found between the groups (P > 0.05) in the publications that evaluated the graded chronic pain scale (GCPS), although an effect size of 0.673 was found in favour of OS (95% CI 0.331 to 1.365, P = 0.272, z = -1.098).

Conclusion: BTX injections and OS applications show significant differences in the MMO of individuals in the early period. In contrast, the MMO of individuals and the GCPS show similar findings in the sixth month and longer follow-up.

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引用次数: 0
Myofunctional therapy for obstructive sleep apnoea.
IF 1.9 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-02-10 DOI: 10.1111/adj.13058
W-Y Li, J-F Masse, F Sériès

Failure of upper airway muscles to develop efficient dilating forces plays a key role in the occurrence of obstructive sleep apnoea in given patients. Thus, myofunctional therapy has been developed to improve the activity/efficacy of the upper airway (UA) dilator muscles, reduce its fatigability and improve mechanical performance. Various programmes, differing in the types of daytime exercises to be completed, as well as in their duration and intensity, have been evaluated. Meta-analysis confirmed the efficacy of myofunctional therapy, with mean apnoea hypopnoea index (AHI) scores decreasing from 28.0 ± 16.2/h to 18.6 ± 13.1/h, and lowest oxygen saturation (LSAT) values improving from 83.2% ± 6.1% to 85.1% ± 7.0%. In children, MT and nasal washing may result in little to no difference in AHI. Integrating oropharyngeal exercises with the use of a smartphone application to complete and record exercise performances represents an innovative turn in the development of ambulatory MT programmes. Since adherence to therapy is a weakness in conventional OSA strategies such as CPAP, this approach to MT is promising, as evidenced by a 90% mean adherence to it after 3 months of using a smart application. There is further need to determine the most effective combination of exercise algorithms and identify the target population most likely to benefit from MT in outpatient training programmes.

上气道肌肉无法产生有效的扩张力是导致患者出现阻塞性睡眠呼吸暂停的关键因素。因此,人们开发了肌功能疗法,以提高上气道(UA)扩张肌的活动/功效,降低其疲劳度并改善机械性能。目前已对各种方案进行了评估,这些方案在日间练习的类型、持续时间和强度方面各不相同。元分析证实了肌功能疗法的疗效,平均呼吸暂停低通气指数(AHI)从 28.0 ± 16.2/h 降至 18.6 ± 13.1/h,最低血氧饱和度(LSAT)从 83.2% ± 6.1% 升至 85.1% ± 7.0%。在儿童中,MT 和鼻腔清洗对 AHI 的影响几乎没有差别。将口咽运动与使用智能手机应用程序来完成和记录运动表现相结合,是流动 MT 计划发展过程中的一次创新。由于坚持治疗是 CPAP 等传统 OSA 策略的一个弱点,因此这种 MT 方法前景广阔,使用智能应用程序 3 个月后,平均坚持治疗率达到 90%。还需要进一步确定最有效的运动算法组合,并确定最有可能从门诊训练计划中的 MT 中受益的目标人群。
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引用次数: 0
Causal relationship between 14 micronutrients and chronic periodontitis: a Mendelian randomization study. 14种微量营养素与慢性牙周炎的因果关系:一项孟德尔随机研究。
IF 1.9 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-01-03 DOI: 10.1111/adj.13056
Z Yu, Y Yang, Z Yu, Z Yan, R Gao

Background: Chronic periodontitis is one of the most common inflammatory diseases worldwide. Micronutrients play a significant impact on health and periodontal disease progression. However, there is still a lack of conclusive studies confirming the causal association of micronutrients with chronic periodontitis.

Materials and methods: Genome-wide association study pooled data on chronic periodontitis were collected from the FinnGen consortium, and 14 micronutrients (calcium, copper, zinc, potassium, magnesium, selenium, iron, carotenoids, vitamin B6, B12, C, D, E and folate) were obtained from the OpenGWAS and UK Biobank Study. Instrumental variables were screened by strict criteria. Five Mendelian randomization (MR) methods were used. Finally, the robustness of the findings was verified by sensitivity analyses.

Results: We found that vitamin D reduced the risk of chronic periodontitis (OR: 0.605, 95%CI: 0.398-0.921, P = 0.019). However, we had no evidence of a significant association between other micronutrients and chronic periodontitis. Multiple sensitivity analyses confirmed the robustness of the findings. A variety of sensitivity analysis methods confirmed the reliability of the results.

Conclusion: In this study, we found a potential causal relationship between vitamin D and chronic periodontitis by MR analysis, whereas we did not find an association between 13 other micronutrients and chronic periodontitis. This result might provide new ideas for the prevention and treatment of chronic periodontitis to some extent. However, despite the rigorous analytical methods used in this study, this finding needs to be interpreted with caution. Further randomized controlled studies might provide more in-depth references to the findings of this study.

背景:慢性牙周炎是世界上最常见的炎症性疾病之一。微量营养素对健康和牙周病的进展有重要影响。然而,仍然缺乏结论性的研究证实微量营养素与慢性牙周炎的因果关系。材料和方法:慢性牙周炎的全基因组关联研究汇总数据来自FinnGen联盟,14种微量营养素(钙、铜、锌、钾、镁、硒、铁、类胡萝卜素、维生素B6、B12、C、D、E和叶酸)来自OpenGWAS和UK Biobank study。通过严格的标准筛选工具变量。采用了5种孟德尔随机化(MR)方法。最后,通过敏感性分析验证了研究结果的稳健性。结果:我们发现维生素D降低慢性牙周炎的风险(OR: 0.605, 95%CI: 0.398-0.921, P = 0.019)。然而,我们没有证据表明其他微量营养素与慢性牙周炎之间有显著的联系。多重敏感性分析证实了研究结果的稳健性。多种灵敏度分析方法验证了结果的可靠性。结论:在本研究中,我们通过MR分析发现了维生素D与慢性牙周炎之间的潜在因果关系,而我们没有发现其他13种微量营养素与慢性牙周炎之间的关联。这一结果可能在一定程度上为慢性牙周炎的防治提供新的思路。然而,尽管在这项研究中使用了严格的分析方法,这一发现需要谨慎解释。进一步的随机对照研究可能为本研究的发现提供更深入的参考。
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引用次数: 0
The status of dental sleep medicine education in Australia and New Zealand in 2024. 2024年澳大利亚和新西兰牙科睡眠医学教育现状。
IF 1.9 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-12-30 DOI: 10.1111/adj.13055
L Tiwari, A Gikas, R Balasubramaniam

Background: This study aimed to evaluate the current status of dental sleep medicine education across dental schools in Australia and New Zealand and gain further insights into the educational background of dentists who have sat the Australasian Sleep Association Fellow of Dental Sleep Medicine examination in 2023.

Methods: Online surveys were carried out, and descriptive statistics were used to analyse data.

Results: All dental schools responded to the survey. Seventy per cent of the schools included dental sleep medicine as part of their curriculum, with an average total teaching time of 2.6 h. Dentists who sat the Fellow of dental sleep medicine examination spent on average 87 h preparing for the examination. All dental schools included discussion on pathophysiology of obstructive sleep apnoea and oral appliance therapy, but did not adequately discuss advanced sleep medicine topics, clinical aspects in treatment planning or contemporary dental sleep medicine topics, whereas dentists that completed the Fellow of dental sleep medicine examination gained knowledge in all aspects of the field.

Conclusion: Findings from the study reveal that dental schools across Australia and New Zealand are not delivering adequate levels of education in dental sleep medicine, and hence the current dental sleep medicine curriculum needs to be reviewed and improved.

背景:本研究旨在评估澳大利亚和新西兰牙科学校的牙科睡眠医学教育现状,并进一步了解2023年参加澳大利亚睡眠协会牙科睡眠医学研究员考试的牙医的教育背景。方法:采用在线调查方法,采用描述性统计方法对数据进行分析。结果:所有牙科学校对调查均有回应。70%的学校将牙科睡眠医学作为课程的一部分,平均总教学时间为2.6小时。参加牙科睡眠医学研究员考试的牙医平均花费87小时准备考试。所有牙科学校都包括阻塞性睡眠呼吸暂停的病理生理学和口腔器械治疗的讨论,但没有充分讨论高级睡眠医学主题、治疗计划的临床方面或当代牙科睡眠医学主题,而完成牙科睡眠医学研究员考试的牙医获得了该领域所有方面的知识。结论:研究结果表明,澳大利亚和新西兰的牙科学校在牙科睡眠医学方面没有提供足够的教育水平,因此目前的牙科睡眠医学课程需要进行审查和改进。
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Australian dental journal
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