Australian Veterinary Journal最新文献

Introduction: The objective of this study was to describe the clinical features, treatments and outcomes of dogs with iron ethylenediaminetetraacetate (EDTA) molluscicide ingestion. We aimed to identify potential predictors of serum iron concentration >54 μmol/L; a cut-off recommended for initiating treatment of human iron toxicosis.

Methods: Medical records across four veterinary hospitals (2013-2019) for dogs with known or suspected iron EDTA molluscicide ingestion were reviewed for signalment, clinical signs, clinicopathological data, treatment regimens and outcomes. Clinical signs of dogs with serum iron concentrations either below or above a cut-off of 54 μmol/L were compared using Fisher's exact test. Association between serum iron and urine discolouration was tested using logistic regression.

Results: Seventy-three dogs were included. The most frequent characteristic was abnormal faeces (n = 47, 64%) as determined by rectal examination, with more dogs that had serum iron >54 μmol/L showing this clinical sign (24/35), compared to dogs with serum iron <54 μmol/L (4/13) (P = 0.025). Clinicopathologic abnormalities included increased base excess (n = 20/49, 20%), hyperglycaemia (n = 13/57, 23%) and hyperlactataemia (n = 12/57, 21%). Fifty-four dogs received deferoxamine chelation (74%), during which 25/42 (60%) dogs had discoloured urine despite all dogs having subsequent iron concentrations <54 μmol/L. Admission serum iron concentration was associated with urine discolouration during hospitalisation (odds ratio 1.046, 95% confidence interval 1.008-1.107, P = 0.011). Sixty-nine dogs (95%) survived to discharge, with 10 dogs (14%) transferred to another veterinarian.

Conclusions: Iron EDTA molluscicide ingestion caused predominantly gastrointestinal clinical signs, and abnormal faeces, as well as urine discolouration during chelation therapy, which may indicate an elevation of serum iron concentration on presentation. Outcome was excellent.

Systemic fungal pathogens typically gain entry through a single portal and disseminate to affect multiple body systems. Infections caused by fungal Penicillium species are rare in dogs, and these cases have a poor prognosis. An unknown Penicillium species was isolated from the right eye of a middle-aged Border Collie without evidence of systemic disease. Due to financial limitations, an extensive diagnostic evaluation could not be performed. Histopathology alone failed to identify the specific causative agent; however, fungal culture on aqueous humor provided the definitive diagnosis. This case highlights the advantage of collecting ocular fluids after enucleation to diagnose atypical fungal infections.

Objective: The aim of this study was to ascertain whether patient age was a significant factor for the accurate identification of compressive intervertebral disc extrusions (IVDE) in Dachshunds using non-contrast computed tomography (CT).

Methods: This retrospective analysis encompassed 150 Dachshunds evaluated for suspected IVDE at a referral hospital in south-eastern Queensland, Australia. Each case underwent diagnostic evaluation by CT, either with or without myelography, or magnetic resonance imaging (MRI), followed by surgical intervention for an intervertebral disc extrusion.

Results: In the <9-year dog cohort, 94.7% (71/75) were diagnosed with IVDE via non-contrast CT and proceeded to surgery. In contrast, the ≥9-year dog cohort, only 56% (42/75) were diagnosed via non-contrast CT, with the remaining 44% (33/75) necessitating CT myelography or MRI for diagnosis. The odds of requiring CT myelography or MRI increased 13.95-fold (95% CI, 4.62-42.13) in Dachshunds aged 9 years or older. Furthermore, each additional year of age was associated with a 0.60 increase in the odds of undergoing these advanced imaging modalities (CT myelography or MRI) (95% CI, 0.49-0.74).

Conclusions: Age significantly affected the efficacy of non-contrast CT in diagnosing IVDE in Dachshunds. Dogs aged 9 years and above were substantially more likely to require CT myelography or MRI due to the reduced visibility of disc extrusions on non-contrast CT. Veterinarians performing advanced imaging on older Dachshunds for suspected IVDE should be aware of the limitations of non-contrast CT in obtaining an accurate diagnosis and localisation of IVDE, and be prepared to perform either CT myelography or MRI if required.

Lymphoma was diagnosed in two wild tawny frogmouths (Podargus strigoides) presented to the Australian Wildlife Health Centre, Healesville Sanctuary, Victoria. The first case presented with extensive feather loss refractory to treatment. Bacterial and fungal folliculitis and beak and feather disease virus were excluded as primary causes, and the bird was euthanised due to poor response to treatment. Histopathological examination of the skin showed an extensive infiltrate of pleomorphic mononuclear leucocytes, suggestive of cutaneous lymphoma. Immunohistochemistry revealed >95% of these cells were CD3 positive, consistent with T cell lymphoma. The second case presented debilitated and in poor body condition and was euthanised due to poor prognosis. Histopathological examination revealed extensive infiltrates of pleomorphic mononuclear leucocytes in multiple tissues, suggestive of disseminated lymphoma. Immunohistochemistry revealed 70%-80% of these leucocytes were Pax5 positive, consistent with a B cell lymphoma. To the authors' knowledge these cases constitute the first report of malignant neoplasms in members of the Order Caprimulgiformes. Cutaneous lymphoma should be considered as a potential differential diagnosis for severe feather loss in tawny frogmouths and other avian species, when other more common causes have been ruled out. Similarly, disseminated lymphoma is a differential diagnosis worthy of consideration in cases of systemic debilitation in tawny frogmouths.

Objective: To investigate the frequency of perioperative acute kidney injury (AKI) in American Society of Anesthesiologists (SA) Grade I canine patients undergoing elective desexing using urine microscopy techniques and assess if pre- and intraoperative factors affect risk of developing AKI.

Design: Prospective observational clinical study conducted between September 2020 and October 2020.

Setting: University teaching hospital.

Animals: Thirty-two female and four male dogs between 5 months and 5 years of age classified as ASA I undergoing elective desexing surgery.

Methods: Urinalysis was performed preoperatively and 20-24 h postoperatively to identify markers of renal tubular injury (RTI), particularly the presence of granular and renal tubular epithelial cell (RTEC) casts on sediment analysis. Dogs underwent a full physical examination and a preoperative assessment including measurement of urine specific gravity (USG), packed cell volume (PCV), total plasma protein and serum creatinine (sCr) was conducted as a part of the desexing programme. Anaesthetic records were examined for any evidence of intraoperative hypotension, defined as a mean arterial pressure (MAP) of <60 mmHg for any duration of time. MAP was measured using an indirect oscillometric technique. For analysis, animals were subdivided into affected and nonaffected groups, with affected animals those that had postoperative increases in granular and RTEC casts. Categorical and comparative analyses were then performed between groups to identify associations of increased casts with pre-, intra- and postoperative variables.

Results: A frequency of RTI of 5.6% was identified. This was accompanied by a significant association between increases in casts with total duration (p = 0.027) and number (p = 0.016) of hypotensive episodes.

Conclusions: RTI is an anaesthetic consideration in ASA I veterinary patients undergoing elective desexing surgery. The identification of an association between the total duration and number of hypotensive episodes and the frequency of RTI highlights the importance of early detection of hypotension along with prompt and effective intervention in veterinary patients.

This case report describes the diagnosis, management and the short- and long-term outcomes of a dog with paraprostatic cysts and associated perineal herniation. A 9-year-old male entire Bearded Collie was referred for a caudal abdominal mass and right perineal hernia noted on routine examination. Computed Tomography (CT) imaging of the abdomen demonstrated a large bilobed fluid filled structure adjacent to the prostate, extending into the peritoneal cavity and the right perineal space, causing perineal herniation and partial obstruction of the right ureter. Surgical excision of the mass was performed and ureteroneocystostomy was required due to involvement of the right ureter. Excisional biopsy, omentalisation of the prostate and right-sided herniorrhaphy utilising an internal obturator muscle flap was performed. Histopathology confirmed the diagnosis of paraprostatic cyst with extensive osseous metaplasia and multifocal chronic-active interstitial prostatitis. The dog re-presented 16 months later with a left-sided perineal hernia and a left-sided herniorrhaphy was performed. Twenty-nine months after the initial surgery the dog presented with stranguria associated with recurrent bilateral perineal herniation and a retroflexed urinary bladder. Cystopexy and colopexy were performed. No sign of recurrence of the paraprostatic cysts was noted intraoperatively. This is the first reported case of surgical excision of paraprostatic cysts with concurrent ureteroneocystostomy. To the authors knowledge, this is also the longest reported case follow up (>4 years) of a dog following complete excision of paraprostatic cysts.

Sporotrichosis is caused by species of the fungus Sporothrix that affect human and several animal species. The transmission of sporotrichosis is classically from an environmental source following penetrating injury. The alternative zoonotic route has gained attention due to the rapid and significant spread of cat-transmitted sporotrichosis in South America and Malaysia, resulting in several thousand human and feline cases in recent decades, especially in Brazil. In Australia, sporotrichosis is sporadic and mainly related to environmental sources. Although feline sporotrichosis is rare in Australia, zoonotic transmission occurred in two of five reported cases, including a recent case cluster, which is reported in this article. The investigation of such cases in Australia is important, as cats not only represent a source of infection living in close proximity with humans, but also, they may represent sentinels for the environmental presence of the fungus. To encourage the investigation and reporting of new veterinary cases, we have reviewed Australian sporotrichosis cases in humans and cats and report a new case cluster of feline sporotrichosis in Perth, WA, Australia, with zoonotic transmission. The index case was a kitten who developed severe facial sporotrichosis with prominent involvement of the nasal planum. Two human cases - one suspected and one confirmed - are also described in the owner, who was a veterinary nurse, and the attending veterinarian, respectively, probably from handling the kitten while not wearing gloves. Later, another mature cat in the same household also became infected. The affected cats were successfully treated using combination of itraconazole and terbinafine. To the best of our knowledge, this is only the second case of cat-transmitted sporotrichosis reported from Australia.

The causative agent of canine heartworm disease, Dirofilaria immitis, requires specific temperature conditions to mature within its mosquito vector, and therefore (re-)infect a canid host. Suitable temperature conditions are not continuously met for locations where most (>97%) Australians and their pet dogs live. The length of the disruption in the transmissibility of D. immitis varies greatly across Australia, and to some degree, between years. We developed an online dashboard 'Transmission Tracker - Dirofilaria' that processes near real-time temperature records across Australia and allows users to enquire about historical and current weather suitability for canine heartworm transmission at any Australian postcode of their interest. This information allows veterinarians to access when, and for how long, heartworm may be transmitted at a specific location, assess the associated risk of infection and advise on a patient-dependent dirofilariosis prevention plan for their canine patients and guardians. Our dashboard is publicly accessible at: https://heartworm-mapping.adelaide.edu.au/shiny/.