Australian Veterinary Journal最新文献

Objective: This study aimed to evaluate the prevalence of dog erythrocyte antigen 1 (DEA 1) blood type in Sydney and to identify any associations between its prevalence and breed, sex and geographic location of these dogs.

Methods: This was a retrospective study of 225 dogs that underwent DEA 1 blood typing while donating or receiving blood products at a single institution between 2020 and 2024. Dogs were DEA 1 positive or negative and blood donors or recipients. Logistic regression was used to evaluate differences in the prevalence of DEA 1 positive results between sex, breed and geographic location. Significance was set at P < 0.05. Reasons for blood transfusion, blood product administered and age were documented.

Results: Of the dogs that were blood typed (n = 225), 48% (108/225) were DEA 1 positive and 52% (117/225) DEA 1 negative, 105 (46.7%) were donors and 120 (53.3%) recipients. The highest prevalence of DEA 1 type positivity was observed in the Golden Retriever (8/9, 88.9%). Recipients presented primarily for haemorrhage (57/120, 47.5%), most frequently receiving whole blood (89/120, 74.2%) with minimal adverse reactions (3/120, 2.5%). No significant differences were identified in prevalence of DEA 1 positive dogs between breed groups, six most common breeds, sex, geographical location or DEA 1 negative blood types.

Conclusions: The prevalence of the DEA 1 blood type in this cohort of dogs in Sydney is comparable to other countries.

Introduction: Sepsis is a leading cause of morbidity and mortality in neonatal foals. Administration of appropriate antimicrobials and early aggressive supportive treatment is central to the efficacious treatment of neonatal sepsis and has proven to positively influence outcomes. The primary aim of our study was to evaluate microorganism results and antimicrobial sensitivities of neonatal foals with a positive blood culture submitted to our intensive care unit (ICU) during 2005-2022. The secondary aim was to compare the results to those of a similar previous study performed at the same ICU during 1999-2004.

Materials and methods: Retrospective analysis of bacterial blood culture results from neonatal foals ≤7 days of age admitted to Scone Equine Hospital between 2005 and 2022 was analysed. Samples were collected at admission. Antimicrobial sensitivity testing was assessed using the Kirby-Bauer disc diffusion method. Susceptibility results from the two study periods were compared using Fisher's exact tests. Statistical significance was achieved at P value <0.05.

Results: From 1621 blood cultures submitted, 380 returned a positive result (380/1621; 23.4%). A total of 402 bacterial isolates were recovered: 55.5% Gram-positive isolates (223/402), 42.6% Gram-negative isolates (171/402) and 1.7% anaerobic isolates (7/409). A significant increase in Gram-positive isolates between time periods was observed (P = 0.002). Gram-negative isolates had significant increases of resistance in seven out of nine antimicrobials tested.

Conclusion: This study provides Australian veterinarians with information on common bacterial pathogens in critically ill neonatal foals to assist with making informed empirical antimicrobial choices to optimise treatment efficacy. Increases in bacterial resistance to commonly administered antimicrobials were observed; therefore, culture and sensitivity testing should guide antimicrobial choices. Judicious use of antimicrobials in equine practice is imperative.

Background: Errors in veterinary clinical settings can lead to patient harm. Morbidity and mortality meetings (M&Ms) are forums to discuss errors and incidents that can lead or have led to adverse outcomes, potential harm or unsafe conditions, with the purpose of improving patient safety in future. Despite growing implementation of M&Ms in veterinary medicine, their effectiveness in improving future patient safety may be constrained by the need for absolute confidentiality during meetings.

Objective: To pilot the use of a simple framework to categorise errors and incidents triggering M&Ms in a multi-specialty Australian veterinary teaching hospital.

Methodology: A retrospective analysis of deidentified M&M summaries over 5 years (2018-2023) from a small animal multi-specialty veterinary teaching hospital. Animal demographic and incident information were extracted, classified by incident type and severity of harm adapted from Wallis and colleagues (2019). Descriptive statistics were produced for error category, severity, incident type and quarter of the year they occurred in. Recommendations were analysed using codebook thematic analysis.

Results: There were 68 cases in total. The most common overall errors were oversight (n = 26/25.0%), drug (n = 20/19.2%), iatrogenic (n = 17, 16.3%) and staff (n = 17, 16.3%). Most cases resulted in temporary harm (n = 36, 52.9%), though 20.6% (n = 14) resulted in death, euthanasia or permanent harm. The most frequent recommendations were 'improving communications and record keeping', improving staff training' and 'ensuring appropriate equipment is available'.

Conclusion: Categorisation of errors using this simple framework can facilitate sharing of information which can be used to refine practices and improve animal safety, without compromising confidentiality of M&M meetings.

Objectives: To identify if chemotherapeutic drugs in the CHOP-based protocol led to an increase in renal parameters in dogs with lymphoma during therapy and investigate whether factors such as prednisolone use or age affected this result.

Methods: Data were obtained retrospectively from private referral practice records of dogs diagnosed with lymphoma receiving a CHOP-based chemotherapy protocol between 2015 and 2019. Dogs included received a CHOP-based protocol as their first treatment, received four full cycles and were in remission at the end of the protocol. Blood samples obtained at baseline and at the time of final chemotherapy administration were analysed for serum biochemistry and haematology including creatinine, urea, phosphate, sodium, potassium, calcium, albumin, total protein, haematocrit, neutrophil and platelet count. Data were analysed using paired t-tests. Changes in the same measures were investigated for possible age effects using Pearson correlations. Changes in these measures were compared between dogs receiving or not receiving prednisolone using 2-sample t-tests without the assumption of equal variances. Changes were jointly compared to both age and prednisolone use in general linear models. Significance was taken as P < 0.05.

Results: Thirty dogs met the inclusion criteria. No significant changes in serum creatinine concentrations were observed. Increased serum albumin concentration at the end of treatment was observed in younger dogs not receiving prednisolone.

Impact/clinical significance: Short-term changes in renal parameters following a CHOP-based chemotherapy protocol in dogs were not observed. Further prospective studies are warranted.

Declaration of interest: No funding was received and no conflict of interest to declare.

The southern brown bandicoot (Isoodon obesulus obesulus) is a small, endangered, Australian, ground-dwelling marsupial. Apart from isolated necropsy reports, there has not been a systematic investigation into the health and causes of death for this species.

Objective: To investigate and document the causes of death and the parasites of free-ranging populations of southern brown bandicoots in southern, central Victoria, Australia.

Methods: Gross necropsy, histopathology and identification of ectoparasites and endoparasites were performed on 62 dead southern brown bandicoots opportunistically collected from July 2011 to January 2018. Molecular methods were used to detect and genetically characterise the presence of Toxoplasma gondii in select tissues.

Results: The vast majority of animals died as a result of either motor vehicle trauma or predation (45/62). A further seven bandicoots died from varying causes with either diagnostic gross or microscopic evidence of pathology, and there were five ejected pouch young. The cause of death was undetermined in another five cases. Toxoplasma gondii was detected in one southern brown bandicoot, which demonstrated polymorphisms in the B1 and SAG3 genes. This is the first definitively documented case of T. gondii infection in this species in Victoria. All of the identified parasites have previously been reported in southern brown bandicoots, apart from a metastrongyloid lungworm, which is reported here for the first time.

Conclusions: Motor vehicle trauma and predation are highlighted as causes of fatality that likely threaten these populations of southern brown bandicoots. Further investigation into the role that disease, particularly toxoplasmosis, may be playing in southern brown bandicoot population decline is recommended.

This case report details an incident of hyperkalaemia that developed under general anaesthesia in a domestic cat with no prior health concerns. A 5-year-old male neutered domestic short-haired cat presented for dental extractions and subsequently developed severe bradycardia and electrocardiographic abnormalities during the procedure. Initial treatment with atropine provided limited improvement, and further investigation revealed a serum potassium concentration of 7.7 mmol/L. Despite interventions, the anaesthetic procedure was aborted due to persistent hyperkalaemia. The cat recovered smoothly postoperatively with complete resolution of hyperkalaemia. This case highlights the importance of monitoring serum potassium levels and electrocardiographic changes in anaesthetised feline patients. Anaesthesia-associated hyperkalaemia in domestic cats is a condition that is under-recognised in Australia. Future studies should focus on the mechanisms behind this electrolyte disturbance, as well as establishing preventive measures and management protocols during general anaesthesia.

This study appraises recent research to critically evaluate knowledge on the factors that influence decisions around the release of rehabilitated koalas to fire-affected home sites. Availability of koala release sites could be compromised at times in the future by the increasing incidence of large and intense bushfires due to climate change. In addition, factors such as the fragmentation of koala habitat and increasing urbanisation impose other threats to the long-term survival of the released koala. Our investigation is conducted as a Critically Appraised Topic (CAT) with eight papers selected to be appraised. We highlight three key areas that affect koala rehabilitation and release to fire-affected home sites - the resilience of the koala in recovery, the adaptation ability of the koala upon release and the components of the fire-affected habitat. The evidence shows that the koala is a good candidate for release given that burnt koalas are resilient in rehabilitation and many can recover and then adapt quickly to their release site. Findings from this study indicate that, when the release site is affected by fire, the conditions that are more favourable for koala release are low severity of fire impact, greater distance from urban areas, connection to unfragmented habitat and previous management of predators. These findings can inform wildlife release and rescue as well as government planning and urban development.

Over the past few decades, the emergence of resistance amongst intestinal parasites of horses to all available anthelmintic classes has emphasised the need for a paradigm shift in parasite control approaches within the Australian equine industry. Findings of a recent Australia-wide research project have provided new insights into intestinal parasites (i.e. strongyles and ascarids) and parasite control from the perspectives of Australian horse breeders and equine veterinarians. The published data have revealed recent trends in parasite prevalence and distribution, breeders' and veterinarians' attitudes and perspectives on controlling horse internal parasites, the efficacy of commonly used anthelmintic products and post-treatment egg reappearance periods. These studies have formed the basis of newly developed guidelines managing and treating gastrointestinal nematodes in horses. Tailored for equine veterinarians, these guidelines contain information on target parasites and risk factors for their transmission, as well as practical advice for surveillance, anthelmintic choice, timing of treatment, testing for anthelmintic resistance and managing refugia. The Australian Guidelines for Equine Internal Parasite Management (AGEIPM) will serve as a pocket companion for equine veterinarians, providing best-practice recommendations grounded in locally conducted scientific research. Dissemination and extension of the AGEIPM to industry will strengthen the client-practitioner relationship. The aim is to reduce reliance on blanket deworming in equine parasite management programs and help curb the progression of resistance to the limited anthelmintic classes available for treating horses.

Veterinary professionals are often confronted with moral conflicts from which moral distress can develop. Moral distress can lead to a cascade of deleterious processes and outcomes including emotional anguish, distress, reduced patient care, and attrition from both the workplace and workforce. The current study established a pilot measure for moral distress in Australian veterinary clinicians, as well as reporting additional sources of moral and ethical conflicts in veterinary practice. The pilot scale was based on adapting the Measure of Moral Distress for Healthcare Professionals (MMD-HP) to the veterinary context and analysing responses from 643 veterinarians in Australia to create the Measure of Moral Distress for Veterinary Clinicians (MMD-VC). The MMD-VC comprised three sub-scales: (1) team communications that compromise patient care, (2) conflicting client interactions and (3) situations perceived as a personal threat. The additional sources of moral and ethical conflict that were reported by respondents to an open-ended survey question reflected two themes: (1) Animal Health, where the conflict arises from the effect of a situation on the animal patient and (2) Human Interactions, where the conflict relates to interpersonal relationships rather than to the animal patient. The results contribute towards developing comprehensive measures of moral and ethical conflict in clinical practice, and these measures can inform and evaluate intervention strategies designed to mitigate the harmful effects of moral distress in veterinarians.

This observational study highlights the apparent lower severity of footrot in goats compared with sheep, the risk of false negative results from elastase tests, the need to clean contractors' equipment between properties and indicates the potential use of kidding (or lambing) time and individual mob biosecurity in managing footrot.