Pub Date : 2019-02-12DOI: 10.33552/WJGWH.2019.01.000525
B. Petrikovsky, EV Zharov, M. Cohen
Numerous studies conclude that risks and benefits of hormonal replacement therapy (HRT) are dose-dependent [1]. The pharmaceutical industry attempted to partially resolve the issue of individualization of HRT by manufacturing at least six different types of Minivelle patches (0.024mg, 0.0375mg, 0.05mg, 0.075mg, and 0.1mg). The choices offered by the pharmaceuticals are useful but fail to caliber dose based on the needs of the individual patient.
{"title":"Individualized Hormone Replacement Therapy Versus Ovarian Transplantation","authors":"B. Petrikovsky, EV Zharov, M. Cohen","doi":"10.33552/WJGWH.2019.01.000525","DOIUrl":"https://doi.org/10.33552/WJGWH.2019.01.000525","url":null,"abstract":"Numerous studies conclude that risks and benefits of hormonal replacement therapy (HRT) are dose-dependent [1]. The pharmaceutical industry attempted to partially resolve the issue of individualization of HRT by manufacturing at least six different types of Minivelle patches (0.024mg, 0.0375mg, 0.05mg, 0.075mg, and 0.1mg). The choices offered by the pharmaceuticals are useful but fail to caliber dose based on the needs of the individual patient.","PeriodicalId":87379,"journal":{"name":"World journal of gynecology & womens health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42161848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-16DOI: 10.33552/wjgwh.2019.01.000524
Tereshchenko
Androsteroma, a hormonally active virializing tumor from the reticular layer of the adrenal cortex, is extremely rare. Variolating ovarian tumors -sertolistromalnokletochnye and steroid cell are also a rare pathology, although they are more common with androsteroma. Androsteroma and virializing ovarian tumors do not differ in the clinical picture. Therefore, the differential diagnosis of these tumors is difficult. However, the determination of the level of androgens and their fractions in the blood, which has become routine in recent years, makes it possible to suspect a source of virilization. Tumor cell secretion androgens and their fractions depends on the origin of the tumor, which is very important to consider when differential diagnosis. Visualization androgensekretiruyusch her tumor and performed echo graphically (US), by computer or magnetic resonance imaging (CT, MRI) of the adrenal glands and organs of a small pelvis and helps in the selection of surgical intervention. The available literature mainly contains a description of individual cases of virializing GTC Hawley, and in publications is not met examples of differential diagnostic errors [1-5].
{"title":"Difficulties and Errors of Differential Diagnostics Androgen-Secreting Tumors of the Addrum and Ovary on The Example of Clinical Case. Results of Treatment","authors":"Tereshchenko","doi":"10.33552/wjgwh.2019.01.000524","DOIUrl":"https://doi.org/10.33552/wjgwh.2019.01.000524","url":null,"abstract":"Androsteroma, a hormonally active virializing tumor from the reticular layer of the adrenal cortex, is extremely rare. Variolating ovarian tumors -sertolistromalnokletochnye and steroid cell are also a rare pathology, although they are more common with androsteroma. Androsteroma and virializing ovarian tumors do not differ in the clinical picture. Therefore, the differential diagnosis of these tumors is difficult. However, the determination of the level of androgens and their fractions in the blood, which has become routine in recent years, makes it possible to suspect a source of virilization. Tumor cell secretion androgens and their fractions depends on the origin of the tumor, which is very important to consider when differential diagnosis. Visualization androgensekretiruyusch her tumor and performed echo graphically (US), by computer or magnetic resonance imaging (CT, MRI) of the adrenal glands and organs of a small pelvis and helps in the selection of surgical intervention. The available literature mainly contains a description of individual cases of virializing GTC Hawley, and in publications is not met examples of differential diagnostic errors [1-5].","PeriodicalId":87379,"journal":{"name":"World journal of gynecology & womens health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42459707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-11DOI: 10.33552/wjgwh.2019.01.000523
Hasib Ahmed.
Endometriosis presents a diagnostic challenge as clinical symptoms do not correlate well with the extent of disease [1]. Cramer, et al. [2] found that menstrual cycle length shorter than 27 days, menses longer than 7 days and severe cramping dysmenorrhea were predictive of endometriosis with relative risks of 2.1 (95%CI 1.5-2.9), 2.4 (95%CI 1.4-4.0) and 6.7(95%CI 4.4-10.2) respectively. The study compared 268 women with infertility and laparoscopically confirmed endometriosis with 3794 women admitted for delivery (controls) using a retrospective questionnaire. The study was limited by recall bias and the criteria for laparoscopic diagnosis were not clearly defined. No significant correlation was found with chronic pelvic pain. The issue has been studied prospectively [3,4] in 134 women scheduled for laparoscopy for chronic pelvic pain (CPP). Dyschezia, dyspareunia, and non-menstrual pain were all identified as predictors of deep infiltrating endometriosis (DIE) with odds ratios of 3.9 (95%CI 1.7-8.9), 4.6 (95%CI 1.5-14.2) and 2.5 (95%CI 1.1-5.6) respectively. Mrs. SF presented with all of these symptoms to a greater or lesser extent. One criticism of Chapron’s study is that the diagnosis was made on laparoscopic appearance without histological confirmation. Visualization alone has been shown to have a positive predictive value (PPV) for endometriosis of 45% and up to 36% of lesions were down staged on histology [5].
{"title":"Case Based Discussion of Surgical Approach to Deep Infiltrating Endometriosis","authors":"Hasib Ahmed.","doi":"10.33552/wjgwh.2019.01.000523","DOIUrl":"https://doi.org/10.33552/wjgwh.2019.01.000523","url":null,"abstract":"Endometriosis presents a diagnostic challenge as clinical symptoms do not correlate well with the extent of disease [1]. Cramer, et al. [2] found that menstrual cycle length shorter than 27 days, menses longer than 7 days and severe cramping dysmenorrhea were predictive of endometriosis with relative risks of 2.1 (95%CI 1.5-2.9), 2.4 (95%CI 1.4-4.0) and 6.7(95%CI 4.4-10.2) respectively. The study compared 268 women with infertility and laparoscopically confirmed endometriosis with 3794 women admitted for delivery (controls) using a retrospective questionnaire. The study was limited by recall bias and the criteria for laparoscopic diagnosis were not clearly defined. No significant correlation was found with chronic pelvic pain. The issue has been studied prospectively [3,4] in 134 women scheduled for laparoscopy for chronic pelvic pain (CPP). Dyschezia, dyspareunia, and non-menstrual pain were all identified as predictors of deep infiltrating endometriosis (DIE) with odds ratios of 3.9 (95%CI 1.7-8.9), 4.6 (95%CI 1.5-14.2) and 2.5 (95%CI 1.1-5.6) respectively. Mrs. SF presented with all of these symptoms to a greater or lesser extent. One criticism of Chapron’s study is that the diagnosis was made on laparoscopic appearance without histological confirmation. Visualization alone has been shown to have a positive predictive value (PPV) for endometriosis of 45% and up to 36% of lesions were down staged on histology [5].","PeriodicalId":87379,"journal":{"name":"World journal of gynecology & womens health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43494129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-08DOI: 10.33552/WJGWH.2019.01.000522
Omiema Ibrahim Idris Ahmed, O. Mandar, Rihab Jaafar Ibrahim, Nada G. Hassan, S. Handady
Omiema Ibrahim Idris Ahmed1, Omer Mohamed Ali Mandar2, Rihab Jaafar Ibrahim3, Nada Gaafar Hassan4 and Siddig Omer Mohamed Handady5* 1Department of Obstetrical & Gynecology, Omdurman Maternity hospital, Sudan 2Faculty of Medicine, Al gadrif University, Sudan 3Department of Obstetrical & Gynecology, Ibrahim Malik hospital, Sudan 4Faculty of Medicine, University of Khartoum, Sudan 5Faculty of Medicine, Al Nahda University, Sudan
Omiema Ibrahim Idris Ahmed1、Omer Mohamed Ali Mandar2、Rihab Jaafar Ibrahim3、Nada Gaafar Hassan4和Siddig Omer Mohammed Handady5*1苏丹奥姆杜尔曼妇产医院妇产科2医学院、Al gadrif大学、苏丹3妇产科、Ibrahim Malik医院、苏丹4医学院、喀土穆大学，苏丹5医学院，苏丹Al-Nahda大学
{"title":"Maternal and Perinatal Outcome Among Pregnant Women with Thrombocytopenia Attending Ibrahim Malik Teaching Hospital- Sudan","authors":"Omiema Ibrahim Idris Ahmed, O. Mandar, Rihab Jaafar Ibrahim, Nada G. Hassan, S. Handady","doi":"10.33552/WJGWH.2019.01.000522","DOIUrl":"https://doi.org/10.33552/WJGWH.2019.01.000522","url":null,"abstract":"Omiema Ibrahim Idris Ahmed1, Omer Mohamed Ali Mandar2, Rihab Jaafar Ibrahim3, Nada Gaafar Hassan4 and Siddig Omer Mohamed Handady5* 1Department of Obstetrical & Gynecology, Omdurman Maternity hospital, Sudan 2Faculty of Medicine, Al gadrif University, Sudan 3Department of Obstetrical & Gynecology, Ibrahim Malik hospital, Sudan 4Faculty of Medicine, University of Khartoum, Sudan 5Faculty of Medicine, Al Nahda University, Sudan","PeriodicalId":87379,"journal":{"name":"World journal of gynecology & womens health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44006193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Endometriosis (EMS) is a common estrogen-dependent gynecological disorder, which affects quality of life and fertility of productive-aged women [1]. Current treatment of EMS is mainly based on surgery and post-operative maintenance treatment of ovarian suppressive agents. A major challenge for women with EMS is the post-operative recurrence [2-3]. Some medical treatments have been suggested for EMS, such as oral contraceptive pills, and gonadotropin-releasing hormone agonists (GnRH-a). GnRH-a is an important treatment modality for EMS, significantly reducing EMSrelated symptoms [4-6].
{"title":"The Mechanism of Single Progesterone as Add-Back Therapy to GnRH-a Administration","authors":"Jiming Chen, Junling Liu, Wei-ming Wei, Ying Cao, Yilin Sun, Huichao Xiao, Yafeng Zheng, Yunfen Jiang, Ruxia Shi","doi":"10.33552/WJGWH.2019.01.000521","DOIUrl":"https://doi.org/10.33552/WJGWH.2019.01.000521","url":null,"abstract":"Endometriosis (EMS) is a common estrogen-dependent gynecological disorder, which affects quality of life and fertility of productive-aged women [1]. Current treatment of EMS is mainly based on surgery and post-operative maintenance treatment of ovarian suppressive agents. A major challenge for women with EMS is the post-operative recurrence [2-3]. Some medical treatments have been suggested for EMS, such as oral contraceptive pills, and gonadotropin-releasing hormone agonists (GnRH-a). GnRH-a is an important treatment modality for EMS, significantly reducing EMSrelated symptoms [4-6].","PeriodicalId":87379,"journal":{"name":"World journal of gynecology & womens health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42340560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01Epub Date: 2019-11-22DOI: 10.33552/wjgwh.2019.03.000555
Rolanda L Lister, Wonder Drake, Baldwin H Scott, Cornelia Graves
Maternal mortality is on the rise in the United States and it disproportionately affects black women. The reasons for this staggering discrepancy hinge on three central issues: First, black women are more likely to have pre-existing cardiovascular morbidity that increase the risk of maternal mortality. Second, black women are more likely to experience adverse pregnancy outcomes which puts them at risk for developing long-term cardiovascular disease. Third, racial bias of providers and perceived racial discrimination from patients (the elephant in the room) impacts black patients' trust in their providers and the medical community at large. Reducing black maternal mortality involves a multi-tiered approach involving the patient, provider and public health policy.
{"title":"Black Maternal Mortality-The Elephant in the Room.","authors":"Rolanda L Lister, Wonder Drake, Baldwin H Scott, Cornelia Graves","doi":"10.33552/wjgwh.2019.03.000555","DOIUrl":"https://doi.org/10.33552/wjgwh.2019.03.000555","url":null,"abstract":"<p><p>Maternal mortality is on the rise in the United States and it disproportionately affects black women. The reasons for this staggering discrepancy hinge on three central issues: First, black women are more likely to have pre-existing cardiovascular morbidity that increase the risk of maternal mortality. Second, black women are more likely to experience adverse pregnancy outcomes which puts them at risk for developing long-term cardiovascular disease. Third, racial bias of providers and perceived racial discrimination from patients (the elephant in the room) impacts black patients' trust in their providers and the medical community at large. Reducing black maternal mortality involves a multi-tiered approach involving the patient, provider and public health policy.</p>","PeriodicalId":87379,"journal":{"name":"World journal of gynecology & womens health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384760/pdf/nihms-1596138.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38199344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-20DOI: 10.33552/WJGWH.2018.01.000520
B. Petrikovsky
The use of hormone-replacement therapy (HRT) has undergone many changes since it was first introduced into clinical practice in the 1940s. At present, the pendulum seems to be swinging back to more acceptance of its use, following a marked reduction in prescriptions after the results of the Women’s Health Initiative (WHI) study were published in the early 2000s [2]. HRT was shown to significantly decrease the incidence of menopausal symptoms, risk of osteoporotic fractures, and improve the overall quality of life. In younger, healthy women (aged 50-60 years), the risk-benefit balance is clearly in favor of using HRT [1-3]. HRT is not risk-free. An increased risk of stroke with HRT has been reported in several studies [4,5].
{"title":"Hormone Replacement Therapy – Computer Assisted Individualized Approach","authors":"B. Petrikovsky","doi":"10.33552/WJGWH.2018.01.000520","DOIUrl":"https://doi.org/10.33552/WJGWH.2018.01.000520","url":null,"abstract":"The use of hormone-replacement therapy (HRT) has undergone many changes since it was first introduced into clinical practice in the 1940s. At present, the pendulum seems to be swinging back to more acceptance of its use, following a marked reduction in prescriptions after the results of the Women’s Health Initiative (WHI) study were published in the early 2000s [2]. HRT was shown to significantly decrease the incidence of menopausal symptoms, risk of osteoporotic fractures, and improve the overall quality of life. In younger, healthy women (aged 50-60 years), the risk-benefit balance is clearly in favor of using HRT [1-3]. HRT is not risk-free. An increased risk of stroke with HRT has been reported in several studies [4,5].","PeriodicalId":87379,"journal":{"name":"World journal of gynecology & womens health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49108967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-14DOI: 10.33552/wjgwh.2018.01.000519
Supramaniam Pr
Over the last four decades, significant developments have occurred within the field of assisted reproduction, initially sparked by the birth of Louise Brown in 1978, who will be forever be known as the first human baby born through in-vitro fertilization (IVF) treatment in the world. The first IVF cycle was based on a nonstimulated ovulatory cycle, in which the oocyte retrieval procedure was performed laparoscopically. IVF, however, was already being performed experimentally in animals, namely rabbits, as early as the 1980’s, with the first IVF human pregnancy reported as early as 1973, but unfortunately resulting in a first trimester loss [1].
{"title":"Assisted Reproductive Technology: Where did the Journey Begin, and where are we Today – A 40-year History","authors":"Supramaniam Pr","doi":"10.33552/wjgwh.2018.01.000519","DOIUrl":"https://doi.org/10.33552/wjgwh.2018.01.000519","url":null,"abstract":"Over the last four decades, significant developments have occurred within the field of assisted reproduction, initially sparked by the birth of Louise Brown in 1978, who will be forever be known as the first human baby born through in-vitro fertilization (IVF) treatment in the world. The first IVF cycle was based on a nonstimulated ovulatory cycle, in which the oocyte retrieval procedure was performed laparoscopically. IVF, however, was already being performed experimentally in animals, namely rabbits, as early as the 1980’s, with the first IVF human pregnancy reported as early as 1973, but unfortunately resulting in a first trimester loss [1].","PeriodicalId":87379,"journal":{"name":"World journal of gynecology & womens health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47002011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-14DOI: 10.33552/WJGWH.2018.01.000518
D. Yuliya, PA Kouznetsov, LS Djokhadze
Over the past years, the rate or preterm birth in Russia has increased from 4.3% in 2012 to 4.2% in 2014 and 4.1 in 2016 [1]. Preterm birth and prematurity are the leading global cause of neonatal death and second leading cause of death in under-fives, after pneumonia [2]. Approximately 5% of preterm births occur before 28 weeks of pregnancy, 15% between 28-31 weeks, 20% at 32-33 weeks, and 60-70% at 34-37 weeks [3]. Preterm birth is associated with nearly 75% of perinatal mortality cases [4,5], and surviving infants are often at a higher risk of disability, including learning difficulties and vision and hearing impairment [2].
{"title":"Combined Use of Cerclage, Obstetric Pessary, and Micronised Progesterone in Recurrent Miscarriage","authors":"D. Yuliya, PA Kouznetsov, LS Djokhadze","doi":"10.33552/WJGWH.2018.01.000518","DOIUrl":"https://doi.org/10.33552/WJGWH.2018.01.000518","url":null,"abstract":"Over the past years, the rate or preterm birth in Russia has increased from 4.3% in 2012 to 4.2% in 2014 and 4.1 in 2016 [1]. Preterm birth and prematurity are the leading global cause of neonatal death and second leading cause of death in under-fives, after pneumonia [2]. Approximately 5% of preterm births occur before 28 weeks of pregnancy, 15% between 28-31 weeks, 20% at 32-33 weeks, and 60-70% at 34-37 weeks [3]. Preterm birth is associated with nearly 75% of perinatal mortality cases [4,5], and surviving infants are often at a higher risk of disability, including learning difficulties and vision and hearing impairment [2].","PeriodicalId":87379,"journal":{"name":"World journal of gynecology & womens health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42419554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-13DOI: 10.33552/WJGWH.2018.01.000517
V. Tskhay, A. Geyman, E. Grebennikova, E. Molgacheva, O. Strelskaya
Trophoblastic disease (TFD) considers rare tumors arising preferentially in reproductive age women. TFD is a relatively rare pathology and occurs at a rate of 1 in 22000 to 1 in 100000 pregnancies [1-3]. Trophoblastic tumors are always associated with pregnancy and can manifest both during pregnancy and after its completion (from several days to several years). The concept of “trophoblastic disease” unites several interconnected various forms of pathological condition of trophoblast: a hydatidiform mole, an invasive mole, choriocarcinoma, a placental bed tumor and an epithelioid trophoblastic tumor [2].
{"title":"Trophoblastic Disease During the Third Trimester of Pregnancy: Ultrasonic Diagnostic, Clinical Case and Perinatal Outcomes","authors":"V. Tskhay, A. Geyman, E. Grebennikova, E. Molgacheva, O. Strelskaya","doi":"10.33552/WJGWH.2018.01.000517","DOIUrl":"https://doi.org/10.33552/WJGWH.2018.01.000517","url":null,"abstract":"Trophoblastic disease (TFD) considers rare tumors arising preferentially in reproductive age women. TFD is a relatively rare pathology and occurs at a rate of 1 in 22000 to 1 in 100000 pregnancies [1-3]. Trophoblastic tumors are always associated with pregnancy and can manifest both during pregnancy and after its completion (from several days to several years). The concept of “trophoblastic disease” unites several interconnected various forms of pathological condition of trophoblast: a hydatidiform mole, an invasive mole, choriocarcinoma, a placental bed tumor and an epithelioid trophoblastic tumor [2].","PeriodicalId":87379,"journal":{"name":"World journal of gynecology & womens health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41964564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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