Pub Date : 2023-09-27DOI: 10.21608/bjas.2023.235453.1246
Mustafa Khammas, Nancy Mikhael, Dalia Abd El-Hassib, Karem Khalil
Background: Vitiligo is a condition where areas of skin lose their pigmentation; oxidative stress and immunological dysregulation have been linked to its development. The purpose of this research was to examine the relationship between Coenzyme Q10 (Co Q10) and Interleukin-6 (IL-6) in the blood of individuals diagnosed with non-segmental vitiligo. The purpose of this article is to provide readers a thorough introduction to vitiligo, including such topics as the disease's epidemiology, categorization, probable causes, underlying pathogenic processes, diagnostic approaches, and several treatment options. Our goal in compiling this summary is to be a useful tool for clinicians and researchers interested in vitiligo by providing an overview of the current state of knowledge. Conclusions: Because of its complex aetiology, vitiligo is difficult to diagnose and treat. Melanocyte dysfunction is fueled by a complex web of elements including genetic susceptibility, autoimmune processes, oxidative stress, and environmental influences. In order to choose the best course of therapy for vitiligo, the severity and duration of the condition must be evaluated. Treatment for this ailment includes a combination of medicinal, phototherapeutic, and psychosocial approaches. Additional research into the roles of
{"title":"Serum concentrations of Co Q10 and Interleukin-6 in patients with non-segmental Vitiligo","authors":"Mustafa Khammas, Nancy Mikhael, Dalia Abd El-Hassib, Karem Khalil","doi":"10.21608/bjas.2023.235453.1246","DOIUrl":"https://doi.org/10.21608/bjas.2023.235453.1246","url":null,"abstract":"Background: Vitiligo is a condition where areas of skin lose their pigmentation; oxidative stress and immunological dysregulation have been linked to its development. The purpose of this research was to examine the relationship between Coenzyme Q10 (Co Q10) and Interleukin-6 (IL-6) in the blood of individuals diagnosed with non-segmental vitiligo. The purpose of this article is to provide readers a thorough introduction to vitiligo, including such topics as the disease's epidemiology, categorization, probable causes, underlying pathogenic processes, diagnostic approaches, and several treatment options. Our goal in compiling this summary is to be a useful tool for clinicians and researchers interested in vitiligo by providing an overview of the current state of knowledge. Conclusions: Because of its complex aetiology, vitiligo is difficult to diagnose and treat. Melanocyte dysfunction is fueled by a complex web of elements including genetic susceptibility, autoimmune processes, oxidative stress, and environmental influences. In order to choose the best course of therapy for vitiligo, the severity and duration of the condition must be evaluated. Treatment for this ailment includes a combination of medicinal, phototherapeutic, and psychosocial approaches. Additional research into the roles of","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"141 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139335670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Neonatal hyperbilirubinemia is a prevalent concern in the early stages of life, often necessitating phototherapy. This study aimed to assess the electrolyte changes following phototherapy in neonates admitted to pediatric department In Benha university hospital. Methods: This study was carried out in the NICU of Benha University Hospital and involved the participation of 61 healthy newborns diagnosed with unconjugated hyperbilirubinemia requiring phototherapy. The research included a comprehensive evaluation, comprising detailed maternal, obstetric, and neonatal histories, meticulous clinical examinations, and a diverse range of investigations. These investigations involved complete blood counts, determination of blood group, profiling of bilirubin levels, and the quantification of electrolyte concentrations (sodium, potassium, chloride, calcium, and magnesium). Blood samples were collected both before and after the phototherapy sessions. Results: This study involved a cohort of 61 cases, with 32 being male (52.5%) and 29 female (47.5%). Their ages had a mean ± SD of 5.77 ± 1.94. 41 cases had a Normal Birth weight. The mode of delivery revealed that 44.3% of cases were delivered through Normal Vaginal Delivery (NVD), while 55.7% were delivered through Cesarean Section (CS). Examining gestational age, the majority (62.3%) fell within the 36–39-week range, 26.2% had a gestational age of ≥40 weeks, and the Mean ± SD gestational age was 38.0 ± 1.84 weeks. Of the cases, 68.9% underwent conventional phototherapy, while 31.1% were treated with LED. Significant differences were observed between pre-and post-treatment Total Bilirubin levels (p<0.001). Conclusions: Our study revealed a significant reduction in total bilirubin levels following phototherapy, along with notable changes in calcium, sodium, and magnesium levels. Serum electrolyte levels were not correlated with mode of delivery or birth weight. Additionally, hypocalcemia after phototherapy was more prevalent in preterm neonates (<36 weeks) compared to term neonates (≥36 weeks).
{"title":"Electrolyte Changes Following Phototherapy in Neonatal unconjugated Hyperbilirubinaemia","authors":"Osama Elfiky, Omima abd-elhaie, walid Abdellatif, Alshaymaa mohamed","doi":"10.21608/bjas.2023.237263.1252","DOIUrl":"https://doi.org/10.21608/bjas.2023.237263.1252","url":null,"abstract":"Background: Neonatal hyperbilirubinemia is a prevalent concern in the early stages of life, often necessitating phototherapy. This study aimed to assess the electrolyte changes following phototherapy in neonates admitted to pediatric department In Benha university hospital. Methods: This study was carried out in the NICU of Benha University Hospital and involved the participation of 61 healthy newborns diagnosed with unconjugated hyperbilirubinemia requiring phototherapy. The research included a comprehensive evaluation, comprising detailed maternal, obstetric, and neonatal histories, meticulous clinical examinations, and a diverse range of investigations. These investigations involved complete blood counts, determination of blood group, profiling of bilirubin levels, and the quantification of electrolyte concentrations (sodium, potassium, chloride, calcium, and magnesium). Blood samples were collected both before and after the phototherapy sessions. Results: This study involved a cohort of 61 cases, with 32 being male (52.5%) and 29 female (47.5%). Their ages had a mean ± SD of 5.77 ± 1.94. 41 cases had a Normal Birth weight. The mode of delivery revealed that 44.3% of cases were delivered through Normal Vaginal Delivery (NVD), while 55.7% were delivered through Cesarean Section (CS). Examining gestational age, the majority (62.3%) fell within the 36–39-week range, 26.2% had a gestational age of ≥40 weeks, and the Mean ± SD gestational age was 38.0 ± 1.84 weeks. Of the cases, 68.9% underwent conventional phototherapy, while 31.1% were treated with LED. Significant differences were observed between pre-and post-treatment Total Bilirubin levels (p<0.001). Conclusions: Our study revealed a significant reduction in total bilirubin levels following phototherapy, along with notable changes in calcium, sodium, and magnesium levels. Serum electrolyte levels were not correlated with mode of delivery or birth weight. Additionally, hypocalcemia after phototherapy was more prevalent in preterm neonates (<36 weeks) compared to term neonates (≥36 weeks).","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139335728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-26DOI: 10.21608/bjas.2023.231001.1233
Mohamed Tawfik, Hamada Khater, Ban Nsaif
Background: The assessment in neonates, such as developmental hip dislocation (DDH) and septic hip arthritis, is very important from a clinical standpoint. In this regard, ultrasound imaging has shown to be invaluable due to the fact that it allows for assessment without the use of ionising radiation. The purpose of this research was to evaluate the usefulness of ultrasonography in the diagnosis of DDH and septic hip arthritis in neonates. Methods: Newborns at Benha University Hospital and other private facilities were analysed using a comparative cross-sectional research methodology. The study population was subjected to in-depth interviews, physical exams, and ultrasound assessments. The ultrasound evaluation looked at the shape of the hip, the location of the femoral head, and the strength of the hip joint. The degree of irregularity was determined by a combination of measurements and visual inspections, such as measuring alpha and beta angles. Patients who had favourable ultrasonography results were monitored and referred to specialists as needed. Conclusions Both the positive and negative predictive capacities of ultrasonography were quite high (80% and 100%, respectively). In addition, a high area under the curve (AUC=0.949) and associated 92% diagnostic accuracy rate were found when employing ROC curve analysis to differentiate DDH from normal findings using hip ultrasonography. Furthermore, a positive family history (p=0.007), oligohydramnios (p=0.003), and caesarean section (p=0.008) were all significantly associated with an increased risk of DDH incidence, as determined by the study's analysis into probable DDH causes based on the analysed data. We conclude that ultrasound is a useful and non-invasive method for assessing hip joint issues in neonates, especially DDH. The clinical examination of newborns with suspected hip abnormalities benefits greatly from its accuracy and its capacity to detect related risk factors.
{"title":"Ultrasound Evaluation of Neonatal Hip Joint Problems”","authors":"Mohamed Tawfik, Hamada Khater, Ban Nsaif","doi":"10.21608/bjas.2023.231001.1233","DOIUrl":"https://doi.org/10.21608/bjas.2023.231001.1233","url":null,"abstract":"Background: The assessment in neonates, such as developmental hip dislocation (DDH) and septic hip arthritis, is very important from a clinical standpoint. In this regard, ultrasound imaging has shown to be invaluable due to the fact that it allows for assessment without the use of ionising radiation. The purpose of this research was to evaluate the usefulness of ultrasonography in the diagnosis of DDH and septic hip arthritis in neonates. Methods: Newborns at Benha University Hospital and other private facilities were analysed using a comparative cross-sectional research methodology. The study population was subjected to in-depth interviews, physical exams, and ultrasound assessments. The ultrasound evaluation looked at the shape of the hip, the location of the femoral head, and the strength of the hip joint. The degree of irregularity was determined by a combination of measurements and visual inspections, such as measuring alpha and beta angles. Patients who had favourable ultrasonography results were monitored and referred to specialists as needed. Conclusions Both the positive and negative predictive capacities of ultrasonography were quite high (80% and 100%, respectively). In addition, a high area under the curve (AUC=0.949) and associated 92% diagnostic accuracy rate were found when employing ROC curve analysis to differentiate DDH from normal findings using hip ultrasonography. Furthermore, a positive family history (p=0.007), oligohydramnios (p=0.003), and caesarean section (p=0.008) were all significantly associated with an increased risk of DDH incidence, as determined by the study's analysis into probable DDH causes based on the analysed data. We conclude that ultrasound is a useful and non-invasive method for assessing hip joint issues in neonates, especially DDH. The clinical examination of newborns with suspected hip abnormalities benefits greatly from its accuracy and its capacity to detect related risk factors.","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"253 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139335737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Although oral and enteral feeding are options, the latter may cause problems such as pain for the patient, malposition of the tube, aspiration pneumonia, sinusitis, epistaxis, and tube occlusion. The purpose of this research was to determine whether early enteral feeding has any effect on the risk of developing significant problems after major surgery. Two hundred intensive care unit (ICU) patients at Benha University Hospitals were randomly assigned to either group A (early feeding) or group B (late feeding) in this prospective cohort observational research. Albumin, prealbumin, transferrin, ALT, AST, ALP, total bilirubin, urea nitrogen, and creatinine were not significantly different between the two groups, however white blood cell counts were significantly different. We observed that 62% of Group A scored a 3, compared to 61% of Group B; 36% of Group A scored a 4, compared to 36% of Group B; 2% of Group A scored a 4, compared to 3% of Group B; and 0% of Group A scored a 4 compared to 3% of Group B. Hypoglycemia during intervention and ICU stay duration >3 days are significantly different between the two groups. When comparing the two groups, there is a notable difference in terms of the occurrence of a new infection, the peak level of C-reactive protein throughout the ICU stay, and the length of time spent on mechanical ventilation. We conclude that early postoperative enteral feeding decreases the risk of infection complications, perhaps resulting in a shorter duration of stay and less need for intensive care.
虽然可以选择口服和肠内喂养，但后者可能会导致患者疼痛、管道位置不正、吸入性肺炎、鼻窦炎、鼻衄和管道堵塞等问题。本研究旨在确定早期肠内喂养是否会影响大手术后出现重大问题的风险。在这项前瞻性队列观察研究中，本哈大学医院的 200 名重症监护室（ICU）患者被随机分配到 A 组（早期喂养）或 B 组（晚期喂养）。白蛋白、前白蛋白、转铁蛋白、谷丙转氨酶、谷草转氨酶、谷草转氨酶、谷丙转氨酶、总胆红素、尿素氮和肌酐在两组间无显著差异，但白细胞计数有显著差异。我们观察到，62% 的 A 组患者评分为 3 分，而 B 组为 61%；36% 的 A 组患者评分为 4 分，而 B 组为 36%；2% 的 A 组患者评分为 4 分，而 B 组为 3%；0% 的 A 组患者评分为 4 分，而 B 组为 3%。干预期间的低血糖和重症监护室住院时间超过 3 天在两组之间存在显著差异。比较两组患者的新感染发生率、整个重症监护室住院期间的 C 反应蛋白峰值水平以及机械通气时间的长短，两组之间存在明显差异。我们的结论是，术后早期肠内喂养可降低感染并发症的风险，从而缩短住院时间，减少对重症监护的需求。
{"title":"Influence of Postoperative Enteral Nutrition on Postsurgical Infections","authors":"Yousry Rezk, Basem Aglan, Eslam Shaboob, Mostafa Mostafa","doi":"10.21608/bjas.2023.234904.1245","DOIUrl":"https://doi.org/10.21608/bjas.2023.234904.1245","url":null,"abstract":"Although oral and enteral feeding are options, the latter may cause problems such as pain for the patient, malposition of the tube, aspiration pneumonia, sinusitis, epistaxis, and tube occlusion. The purpose of this research was to determine whether early enteral feeding has any effect on the risk of developing significant problems after major surgery. Two hundred intensive care unit (ICU) patients at Benha University Hospitals were randomly assigned to either group A (early feeding) or group B (late feeding) in this prospective cohort observational research. Albumin, prealbumin, transferrin, ALT, AST, ALP, total bilirubin, urea nitrogen, and creatinine were not significantly different between the two groups, however white blood cell counts were significantly different. We observed that 62% of Group A scored a 3, compared to 61% of Group B; 36% of Group A scored a 4, compared to 36% of Group B; 2% of Group A scored a 4, compared to 3% of Group B; and 0% of Group A scored a 4 compared to 3% of Group B. Hypoglycemia during intervention and ICU stay duration >3 days are significantly different between the two groups. When comparing the two groups, there is a notable difference in terms of the occurrence of a new infection, the peak level of C-reactive protein throughout the ICU stay, and the length of time spent on mechanical ventilation. We conclude that early postoperative enteral feeding decreases the risk of infection complications, perhaps resulting in a shorter duration of stay and less need for intensive care.","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139335782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-25DOI: 10.21608/bjas.2023.237306.1253
Khaled Salama, Mohammed Elnory, Ali A. Bendary, Ahmed Mohammed
Background: The First-time mothers and their unborn babies rely heavily on skilled management of labour progression. Vaginal exams (VE) are the gold standard for gauging cervical dilation and foetal head position. The purpose of this research was to examine how useful transperineal ultrasonography (TPUS) is for tracking labour. Methods: Thirty-six first-time mothers were included in this prospective observational research. All of the women were at least 18 years old and carrying a single baby during 37 to 41 weeks' gestation. After doing a transvaginal ultrasound (TPUS), the doctor took notes on the mother's cervical dilatation, the foetal head descent, and the head position of the baby. The results of the VE were compared to these measures. The average age of the participants was determined to be 33 years and 7.4 months. The average body mass index was 27.31.3 kg/m2. The average gestational age was 39 weeks and 1 day. There was a favourable connection between the foetal head station as measured by VE and the Head-perineum distance as measured by US (p0.001). There was a favourable connection between the foetal head station as measured by VE and the Head-perineum distance as measured by US (p0.001). Women were more likely to comply with and be satisfied with TPUS (66.7% vs. 38.9% with VE, p 0.001) than males were with VE. In conclusion, TPUS shows potential as a safe and user-friendly method for tracking the development of labour in first-time mothers. Our results show that TPUS measures correlate well with traditional vaginal checks at many time points during childbirth.
背景：初产妇及其胎儿在很大程度上依赖于熟练的分娩进展管理。阴道检查（VE）是测量宫颈扩张和胎头位置的黄金标准。本研究旨在探讨经会阴超声波检查（TPUS）在跟踪产程方面的作用。研究方法这项前瞻性观察研究共纳入了 36 名初产妇。所有产妇都至少年满 18 岁，在妊娠 37 至 41 周期间怀有单胎。在进行经阴道超声波检查（TPUS）后，医生记录了产妇的宫颈扩张情况、胎头下降情况和胎儿的头部位置。VE 的结果与这些测量结果进行了比较。参与者的平均年龄为 33 岁零 7.4 个月。平均体重指数为 27.31.3 kg/m2。平均胎龄为 39 周零 1 天。用 VE 测量的胎头位置与用 US 测量的胎头-会阴距离之间存在有利的联系（P0.001）。用 VE 测量的胎头位置与用 US 测量的胎头-会阴距离之间存在有利的联系（p0.001）。与男性相比，女性更愿意接受 TPUS（66.7%，而 VE 为 38.9%，P 0.001），并对 TPUS 感到满意。总之，TPUS 作为一种安全且用户友好的方法，在跟踪初产妇的产程发展方面显示出了潜力。我们的研究结果表明，在分娩过程中的许多时间点，TPUS 测量与传统的阴道检查有很好的相关性。
{"title":"Is sonopartogram of value in monitoring the progress of labor?observational study","authors":"Khaled Salama, Mohammed Elnory, Ali A. Bendary, Ahmed Mohammed","doi":"10.21608/bjas.2023.237306.1253","DOIUrl":"https://doi.org/10.21608/bjas.2023.237306.1253","url":null,"abstract":"Background: The First-time mothers and their unborn babies rely heavily on skilled management of labour progression. Vaginal exams (VE) are the gold standard for gauging cervical dilation and foetal head position. The purpose of this research was to examine how useful transperineal ultrasonography (TPUS) is for tracking labour. Methods: Thirty-six first-time mothers were included in this prospective observational research. All of the women were at least 18 years old and carrying a single baby during 37 to 41 weeks' gestation. After doing a transvaginal ultrasound (TPUS), the doctor took notes on the mother's cervical dilatation, the foetal head descent, and the head position of the baby. The results of the VE were compared to these measures. The average age of the participants was determined to be 33 years and 7.4 months. The average body mass index was 27.31.3 kg/m2. The average gestational age was 39 weeks and 1 day. There was a favourable connection between the foetal head station as measured by VE and the Head-perineum distance as measured by US (p0.001). There was a favourable connection between the foetal head station as measured by VE and the Head-perineum distance as measured by US (p0.001). Women were more likely to comply with and be satisfied with TPUS (66.7% vs. 38.9% with VE, p 0.001) than males were with VE. In conclusion, TPUS shows potential as a safe and user-friendly method for tracking the development of labour in first-time mothers. Our results show that TPUS measures correlate well with traditional vaginal checks at many time points during childbirth.","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"170 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139336500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-25DOI: 10.21608/bjas.2023.235536.1247
Mohammed Shaath, Samy Mohamed, Neveen Sorour, Asmaa Adel El-Fallah, Karem Ibrahim
Background: ED is disease with several potential causes, including high blood pressure and diabetes. Serum endocan, MPV, and NLR are only a few of the biomarkers suggested to measure the severity of this inflammatory response. The goals of this study are to examine the relationship between erectile dysfunction and serum endocan level, mean platelet volume, and neutrophil-to-lymphocyte ratio. Serum endocan Level, Mean Platelet Volume, and Neutrophil to Lymphocyte Ratio in patients with erectile dysfunction were retrieved from the Medline databases (Pub Med and Medscape) until the year 2022. Research Studies were chosen after being objectively evaluated by two reviewers. If they met any of the following criteria, we considered them for inclusion: First, it must be written in English. 2. Appearing in journals with a strict peer review process. Third, explain why serum endocan, MCV, and the neutrophil-to-lymphocyte ratio are important in ED patients. Extraction of Data: Research Studies were not included if they did not meet the inclusion criteria. Ethical permission, eligibility criteria, controls, information, and well-defined evaluation measures were all factors in determining the study's quality. Our concerned research results were captured by independently abstracting data utilising a data collecting form from each qualifying study. We conclude that Endocan, MPV, and NLR are indicators implicated in the pathogenesis of ED in individuals with diabetes and hypertension. Endocan and MPV are markers of erectile dysfunction severity in people with diabetes and hypertension
背景：ED 是一种有多种潜在病因的疾病，包括高血压和糖尿病。血清内皮素、血小板平均体积和 NLR 只是衡量这种炎症反应严重程度的几种生物标志物。本研究旨在探讨勃起功能障碍与血清内皮素水平、平均血小板体积和中性粒细胞与淋巴细胞比率之间的关系。研究人员从 Medline 数据库（Pub Med 和 Medscape）中检索了勃起功能障碍患者的血清内皮素水平、平均血小板体积和中性粒细胞与淋巴细胞比率，检索时间截止到 2022 年。研究报告由两名审稿人进行客观评估后选出。如果符合以下任何一项标准，我们就会考虑将其纳入：首先，必须用英语撰写。2.出现在有严格同行评审程序的期刊上。三、解释为什么血清内皮细胞、MCV 和中性粒细胞与淋巴细胞比值对 ED 患者很重要。提取数据：不符合纳入标准的研究未被纳入。伦理许可、资格标准、对照、信息和明确的评估措施都是决定研究质量的因素。我们利用每项合格研究的数据收集表独立抽取数据，从而获得相关研究结果。我们得出结论：Endocan、MPV 和 NLR 是与糖尿病和高血压患者 ED 发病机制有关的指标。Endocan和MPV是糖尿病和高血压患者勃起功能障碍严重程度的标志物
{"title":"Serum Endocan Level, Mean Platelet Volume and Neutrophil to Lymphocyte Ratio in Patients with Erectile Dysfunction: a narrative review","authors":"Mohammed Shaath, Samy Mohamed, Neveen Sorour, Asmaa Adel El-Fallah, Karem Ibrahim","doi":"10.21608/bjas.2023.235536.1247","DOIUrl":"https://doi.org/10.21608/bjas.2023.235536.1247","url":null,"abstract":"Background: ED is disease with several potential causes, including high blood pressure and diabetes. Serum endocan, MPV, and NLR are only a few of the biomarkers suggested to measure the severity of this inflammatory response. The goals of this study are to examine the relationship between erectile dysfunction and serum endocan level, mean platelet volume, and neutrophil-to-lymphocyte ratio. Serum endocan Level, Mean Platelet Volume, and Neutrophil to Lymphocyte Ratio in patients with erectile dysfunction were retrieved from the Medline databases (Pub Med and Medscape) until the year 2022. Research Studies were chosen after being objectively evaluated by two reviewers. If they met any of the following criteria, we considered them for inclusion: First, it must be written in English. 2. Appearing in journals with a strict peer review process. Third, explain why serum endocan, MCV, and the neutrophil-to-lymphocyte ratio are important in ED patients. Extraction of Data: Research Studies were not included if they did not meet the inclusion criteria. Ethical permission, eligibility criteria, controls, information, and well-defined evaluation measures were all factors in determining the study's quality. Our concerned research results were captured by independently abstracting data utilising a data collecting form from each qualifying study. We conclude that Endocan, MPV, and NLR are indicators implicated in the pathogenesis of ED in individuals with diabetes and hypertension. Endocan and MPV are markers of erectile dysfunction severity in people with diabetes and hypertension","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"242 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139336202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-24DOI: 10.21608/bjas.2023.232405.1236
Mohamed Mohamed, Mohamed El-Noury, Ibrahim Sayed, Abdel-Halim Abdel-Halim
: Background: Abnormal hysteroscopy, laboratory testing, imaging, and other diagnostic procedures may all be necessary to determine the cause of abnormal uterine bleeding (AUB), which is defined as bleeding from the uterus that varies in frequency, regularity, length, or quantity as typically reported by the woman. The purpose of this study is to evaluate the value of chromo hysteroscopy in diagnosing and treating abnormal uterine bleeding in women. The Components and Procedures: Over the course of a year, 115 women with AUB problems were surveyed at the outpatient clinic of the Department of gynaecology and obstetrics at Benha University's department of medicine. Chromo hysteroscopy, performed with 5 ml of 1% methylene blue, was performed after conventional hysteroscopy. Distinct staining patterns seen. Staining that was concentrated in one area was termed positive, while staining that was more evenly distributed was regarded normal. These results were compared to those that had already been observed (on conventional hysteroscopy). Differentially stained regions were sampled for biopsies. The correlation between histopathology and hysteroscopic and chromo-hysteroscopic results was investigated. It was determined that chromo hysteroscopy had a high rate of success in diagnosing endometrial illness. The percentages for sensitivity (92.54%), specificity (83.33%), PPV (88.57%), and NPV (-92.54%) are as follows: (88.89 percent ). In addition to the 16 instances of atrophic endometritis, 28 cases of simple endometrial hyperplasia, 4 cases of atypical endometrial hyperplasia, and a new single case of endometrial cancer, the chromo hysteroscopy method resulted to the detection of 50 additional novel endometrial histopathologies. The diagnosis accuracy of traditional hysteroscopy for AUB is boosted by chromo hysteroscopy, as a result.
{"title":"Role of Chromo Hysteroscopy in Evaluation of Endometrial Pathology in Female with Abnormal Uterine Bleeding.","authors":"Mohamed Mohamed, Mohamed El-Noury, Ibrahim Sayed, Abdel-Halim Abdel-Halim","doi":"10.21608/bjas.2023.232405.1236","DOIUrl":"https://doi.org/10.21608/bjas.2023.232405.1236","url":null,"abstract":": Background: Abnormal hysteroscopy, laboratory testing, imaging, and other diagnostic procedures may all be necessary to determine the cause of abnormal uterine bleeding (AUB), which is defined as bleeding from the uterus that varies in frequency, regularity, length, or quantity as typically reported by the woman. The purpose of this study is to evaluate the value of chromo hysteroscopy in diagnosing and treating abnormal uterine bleeding in women. The Components and Procedures: Over the course of a year, 115 women with AUB problems were surveyed at the outpatient clinic of the Department of gynaecology and obstetrics at Benha University's department of medicine. Chromo hysteroscopy, performed with 5 ml of 1% methylene blue, was performed after conventional hysteroscopy. Distinct staining patterns seen. Staining that was concentrated in one area was termed positive, while staining that was more evenly distributed was regarded normal. These results were compared to those that had already been observed (on conventional hysteroscopy). Differentially stained regions were sampled for biopsies. The correlation between histopathology and hysteroscopic and chromo-hysteroscopic results was investigated. It was determined that chromo hysteroscopy had a high rate of success in diagnosing endometrial illness. The percentages for sensitivity (92.54%), specificity (83.33%), PPV (88.57%), and NPV (-92.54%) are as follows: (88.89 percent ). In addition to the 16 instances of atrophic endometritis, 28 cases of simple endometrial hyperplasia, 4 cases of atypical endometrial hyperplasia, and a new single case of endometrial cancer, the chromo hysteroscopy method resulted to the detection of 50 additional novel endometrial histopathologies. The diagnosis accuracy of traditional hysteroscopy for AUB is boosted by chromo hysteroscopy, as a result.","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139336748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-31DOI: 10.21608/bjas.2023.225787.1214
Hazem Elsayed, Mohamed Elbarbary, Ehab Oraby, Ibrahim Fakhreldeen, S. Elgazzar
Purpose: To assess role of intraoperative endoscopy in antireflux procedure regard to detection of gastroesophageal junction and assessment of tightness of wrap. Background: Due to immaturity of the lower esophageal sphincter, which results in the retrograde passage of stomach contents into the oesophagus, gastroesophageal reflux disease is the most prevalent gastroenterologic problem requiring referral to a paediatric gastroenterologist during infancy. Patients and methods: This prospective study included 30 patient of pediatric Age less than 18 years old with GERD resistant to conservative treatment. This study was performed at Benha university hospital and Cairo University Specialized Pediatric Hospital at period from October, 2020 till October, 2022. The procedure was authorised by the medical school's ethics committee. Written informed permission was acquired from the parents of all patients; all patients after informed consent were subjected to laparoscopic Nissen fundoplication. During treatment procedure, endoscopy had been used to locate gastroesophageal junction (GEJ) and to assess tightness of performed valve. Results: there is significant decrease in early post-operative complication rate as early dysphagia 23.3%, early vomiting 10%, no cases of post-operative bleeding or post-operative pneumothorax or esophageal perforation, operative time was seen to be substantially longer in our procedure, the incidence of late postoperative dysphagia and gas bloat syndrome was statistically lower in current study.
{"title":"Role of Intraoperative Endoscopy during Laparoscopic Antireflux Procedure in Children","authors":"Hazem Elsayed, Mohamed Elbarbary, Ehab Oraby, Ibrahim Fakhreldeen, S. Elgazzar","doi":"10.21608/bjas.2023.225787.1214","DOIUrl":"https://doi.org/10.21608/bjas.2023.225787.1214","url":null,"abstract":"Purpose: To assess role of intraoperative endoscopy in antireflux procedure regard to detection of gastroesophageal junction and assessment of tightness of wrap. Background: Due to immaturity of the lower esophageal sphincter, which results in the retrograde passage of stomach contents into the oesophagus, gastroesophageal reflux disease is the most prevalent gastroenterologic problem requiring referral to a paediatric gastroenterologist during infancy. Patients and methods: This prospective study included 30 patient of pediatric Age less than 18 years old with GERD resistant to conservative treatment. This study was performed at Benha university hospital and Cairo University Specialized Pediatric Hospital at period from October, 2020 till October, 2022. The procedure was authorised by the medical school's ethics committee. Written informed permission was acquired from the parents of all patients; all patients after informed consent were subjected to laparoscopic Nissen fundoplication. During treatment procedure, endoscopy had been used to locate gastroesophageal junction (GEJ) and to assess tightness of performed valve. Results: there is significant decrease in early post-operative complication rate as early dysphagia 23.3%, early vomiting 10%, no cases of post-operative bleeding or post-operative pneumothorax or esophageal perforation, operative time was seen to be substantially longer in our procedure, the incidence of late postoperative dysphagia and gas bloat syndrome was statistically lower in current study.","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139347256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-30DOI: 10.21608/bjas.2023.230033.1232
Ahmed Diab, Ahmed Huzayyin, Hesham El-Batsh
: The jet-pump is a device used for the entraining of a suction flow using a high-energy motive jet. The objective of jet-pump is achieved by three main parts: jet-nozzle, mixing chamber and diffuser. The jet-pump performance is governed by geometrical parameters that shape these parts. In this study, the most crucial geometrical parameters that influence performance are investigated by an experimental and numerical parametric study, these parameters are mixing chamber relative length ( ), motive nozzle relative spacing (S) and area ratio between the mixing chamber and the jet orifice ( ). Besides the parametric study, the experimental work also provides the necessary data used to validate the numerical approach, which is concluded using 2-D simulation with transition Shear-Stress Transport (SST) as a turbulence model after showing very good agreement with the experimental data. Eventually, numerical simulation is used to perform design optimization to specify the design that attains the optimum performance by Implementation the design of experiments (DOE). According to the parametric study, it is found that area ratio has the most significant impact on the jet-pump performance and operating conditions, and the highest maximum efficiency of 35.8 % is obtained at pressure ratio of 0.28 and mass ratio of 1.25 for = 4 using of 7.3 and S of 0.785. While the optimum performance is found to be within optimum mass ratio range of (2.25 - 2.96) and maximum efficiency range of (32
{"title":"Experimental and Numerical Design Optimization for the Geometrical Parameters Affecting Jet-pump Performance.","authors":"Ahmed Diab, Ahmed Huzayyin, Hesham El-Batsh","doi":"10.21608/bjas.2023.230033.1232","DOIUrl":"https://doi.org/10.21608/bjas.2023.230033.1232","url":null,"abstract":": The jet-pump is a device used for the entraining of a suction flow using a high-energy motive jet. The objective of jet-pump is achieved by three main parts: jet-nozzle, mixing chamber and diffuser. The jet-pump performance is governed by geometrical parameters that shape these parts. In this study, the most crucial geometrical parameters that influence performance are investigated by an experimental and numerical parametric study, these parameters are mixing chamber relative length ( ), motive nozzle relative spacing (S) and area ratio between the mixing chamber and the jet orifice ( ). Besides the parametric study, the experimental work also provides the necessary data used to validate the numerical approach, which is concluded using 2-D simulation with transition Shear-Stress Transport (SST) as a turbulence model after showing very good agreement with the experimental data. Eventually, numerical simulation is used to perform design optimization to specify the design that attains the optimum performance by Implementation the design of experiments (DOE). According to the parametric study, it is found that area ratio has the most significant impact on the jet-pump performance and operating conditions, and the highest maximum efficiency of 35.8 % is obtained at pressure ratio of 0.28 and mass ratio of 1.25 for = 4 using of 7.3 and S of 0.785. While the optimum performance is found to be within optimum mass ratio range of (2.25 - 2.96) and maximum efficiency range of (32","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139348199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-30DOI: 10.21608/bjas.2023.227728.1223
Ihab Abdallah, Samah Ibrahim, Abeer Abd El-Maksood, Miada Saleh
: This article provides a concise overview of research on the incidence of telogen effluvium among COVID-19 survivors working at Benha University Hospitals. Temporary hair loss due to a variety of circumstances, including physical and mental stress, is known medically as telogen effluvium. Due of the unusual nature of the COVID-19 pandemic, it is vital to comprehend the possible repercussions on the well-being of health care workers, including any severe effects on their physical health. The purpose of this research is to examine the incidence of telogen effluvium among the rehabilitated medical staff of Benha University Hospitals. The researchers evaluated the state of these people's hair in detail, taking into account issues including hair thinning, shedding, and complete hair loss. The purpose of this research is to provide light on the possible influence of COVID-19 on the hair health of healthcare professionals by examining the prevalence of telogen effluvium.
{"title":"Review article in telogen effluvium","authors":"Ihab Abdallah, Samah Ibrahim, Abeer Abd El-Maksood, Miada Saleh","doi":"10.21608/bjas.2023.227728.1223","DOIUrl":"https://doi.org/10.21608/bjas.2023.227728.1223","url":null,"abstract":": This article provides a concise overview of research on the incidence of telogen effluvium among COVID-19 survivors working at Benha University Hospitals. Temporary hair loss due to a variety of circumstances, including physical and mental stress, is known medically as telogen effluvium. Due of the unusual nature of the COVID-19 pandemic, it is vital to comprehend the possible repercussions on the well-being of health care workers, including any severe effects on their physical health. The purpose of this research is to examine the incidence of telogen effluvium among the rehabilitated medical staff of Benha University Hospitals. The researchers evaluated the state of these people's hair in detail, taking into account issues including hair thinning, shedding, and complete hair loss. The purpose of this research is to provide light on the possible influence of COVID-19 on the hair health of healthcare professionals by examining the prevalence of telogen effluvium.","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139347949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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