Pub Date : 2023-10-30DOI: 10.21608/bjas.2023.241988.1268
A. El-Taweel, Hamza Mohamed, Fatma El-Esawy, Essam Akl, Nehal Abd El-Aziz
{"title":"Immunohistochemical Study of Cyclin Dependant Kinase5 (CDK5) in Some Hyperproliferative Skin Disorders","authors":"A. El-Taweel, Hamza Mohamed, Fatma El-Esawy, Essam Akl, Nehal Abd El-Aziz","doi":"10.21608/bjas.2023.241988.1268","DOIUrl":"https://doi.org/10.21608/bjas.2023.241988.1268","url":null,"abstract":"","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139310852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: The COVID-19 The new coronavirus SARS-CoV-2 pandemic has not only profoundly altered surgical treatment across the world, but it has also presented unprecedented difficulties to global healthcare systems. There has been a significant change in how anaesthesia and infection control are handled in perioperative settings due to the increased potential of viral transmission. Strict procedures have been implemented to guarantee the safety of patients and healthcare personnel due to the highly infectious nature of the virus and its potentially devastating clinical effects.. Objective: The goal of this study was to provide the anesthesia care provider with an understanding of the basics, clinical aspects and recent advances of anesthesia management and perioperative infection control in coronavirus patients in order to diminish related morbidity and to avoid adverse perioperative event. Conclusions: The Patients who have healed with COVID-19 may be posted for elective procedures within 0-2 weeks after receiving negative results for SARS-CoV-2. As more and more COVID-19 survivors become surgical candidates, it becomes imperative to do a thorough preoperative examination and risk assessment before admitting them. In the lack of strong scientific data on outcomes for these individuals following elective procedures, integrating excellent clinical skills and a range of diagnostic studies may allow us to evaluate each patient.
{"title":"Anesthesia Management and Perioperative Infection Control in Patients with the Novel Coronavirus","authors":"Ehab Abd-alazeem, Marwa Abouseeda, Mahmoud Elsayed","doi":"10.21608/bjas.2023.238631.1258","DOIUrl":"https://doi.org/10.21608/bjas.2023.238631.1258","url":null,"abstract":"Background: The COVID-19 The new coronavirus SARS-CoV-2 pandemic has not only profoundly altered surgical treatment across the world, but it has also presented unprecedented difficulties to global healthcare systems. There has been a significant change in how anaesthesia and infection control are handled in perioperative settings due to the increased potential of viral transmission. Strict procedures have been implemented to guarantee the safety of patients and healthcare personnel due to the highly infectious nature of the virus and its potentially devastating clinical effects.. Objective: The goal of this study was to provide the anesthesia care provider with an understanding of the basics, clinical aspects and recent advances of anesthesia management and perioperative infection control in coronavirus patients in order to diminish related morbidity and to avoid adverse perioperative event. Conclusions: The Patients who have healed with COVID-19 may be posted for elective procedures within 0-2 weeks after receiving negative results for SARS-CoV-2. As more and more COVID-19 survivors become surgical candidates, it becomes imperative to do a thorough preoperative examination and risk assessment before admitting them. In the lack of strong scientific data on outcomes for these individuals following elective procedures, integrating excellent clinical skills and a range of diagnostic studies may allow us to evaluate each patient.","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139311571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-29DOI: 10.21608/bjas.2023.240656.1265
Samia Abdel-monem, G. Hammad, sherif el tregy, Marwa Mahgoub, Ola Mohamed
Background: Knee osteoarthritis is a chronic joint disorder characterized by progressive breakdown of articular cartilage, disability, and loss of health related quality of life which may demand total knee replacement. Assessment of the patients' outcome is essential to feature the joint replacement impact on the general health as well as the physical and the psychological status. Several scores were developed for this purpose . Objective: This review article aims to assess outcome of a total knee arthroplasty on OA patients regarding physical status (pain, function, posture
背景：膝关节骨关节炎是一种慢性关节疾病，其特点是关节软骨逐渐损坏、残疾和与健康相关的生活质量下降，可能需要进行全膝关节置换。评估患者的疗效对于了解关节置换术对总体健康以及生理和心理状态的影响至关重要。为此开发了几种评分方法。目的：这篇综述性文章旨在评估全膝关节置换术对 OA 患者身体状况（疼痛、功能、姿势、生活质量）的影响。
{"title":"Assessment of Physical Status and Quality of Life of Osteoarthritis Patients After Total Knee Arthroplasty","authors":"Samia Abdel-monem, G. Hammad, sherif el tregy, Marwa Mahgoub, Ola Mohamed","doi":"10.21608/bjas.2023.240656.1265","DOIUrl":"https://doi.org/10.21608/bjas.2023.240656.1265","url":null,"abstract":"Background: Knee osteoarthritis is a chronic joint disorder characterized by progressive breakdown of articular cartilage, disability, and loss of health related quality of life which may demand total knee replacement. Assessment of the patients' outcome is essential to feature the joint replacement impact on the general health as well as the physical and the psychological status. Several scores were developed for this purpose . Objective: This review article aims to assess outcome of a total knee arthroplasty on OA patients regarding physical status (pain, function, posture","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"244 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139311511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Vitiligo is an epidermal depigmentation condition where melanocytes and melanin disappear, affecting one's appearance and self-esteem. Lymphocytes are only one of several cell types that have the polymorphic enzyme serum adenosine deaminase (ADA) on their surface. It has a crucial role in T lymphocyte development and function. The goal of this study is to examine the levels of adenosine deaminase in the serum of vitiligo patients and compare them to those of healthy individuals. Topics and Techniques: Sixty vitiligo patients and twenty age-and sex-matched healthy volunteers made up the patients' group. The Vitiligo Extent Tensity Index was used to quantify the level of skin discoloration caused by vitiligo.
背景：白癜风是一种表皮色素脱失症，黑色素细胞和黑色素消失，影响患者的容貌和自尊。淋巴细胞只是表面具有多态性血清腺苷脱氨酶（ADA）的几种细胞类型之一。它在 T 淋巴细胞的发育和功能中起着至关重要的作用。本研究的目的是检测白癜风患者血清中腺苷脱氨酶的水平，并与健康人进行比较。课题和技术：六十名白癜风患者和二十名年龄与性别匹配的健康志愿者组成患者组。采用白癜风范围强度指数来量化白癜风引起的皮肤脱色程度。
{"title":"Evaluation of Serum Level of Adenosine Deaminase in Patients with Vitiligo","authors":"Khaled Hussein, Mohamed Hussein, Amira Noureldin, Heba Hesham","doi":"10.21608/bjas.2023.240636.1262","DOIUrl":"https://doi.org/10.21608/bjas.2023.240636.1262","url":null,"abstract":"Background: Vitiligo is an epidermal depigmentation condition where melanocytes and melanin disappear, affecting one's appearance and self-esteem. Lymphocytes are only one of several cell types that have the polymorphic enzyme serum adenosine deaminase (ADA) on their surface. It has a crucial role in T lymphocyte development and function. The goal of this study is to examine the levels of adenosine deaminase in the serum of vitiligo patients and compare them to those of healthy individuals. Topics and Techniques: Sixty vitiligo patients and twenty age-and sex-matched healthy volunteers made up the patients' group. The Vitiligo Extent Tensity Index was used to quantify the level of skin discoloration caused by vitiligo.","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139311860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-27DOI: 10.21608/bjas.2023.237012.1251
Mohamed EL-Hamady, S. Abd-Elmaksoud, Asmaa Mohamed, Nermeen Abdullah
: The focus here is on evaluating individuals with coronary heart disease from a psychological perspective. Outpatient clinics at Shebin Elkom teaching hospital and Benha University Hospital provided the sample of 400 participants; 200 patients with CHD and 200 healthy control volunteers were evaluated using the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID1) and the Structured Clinical Interview for DSM-IV Axis II Disorders (SCID11), respectively. Patients with coronary heart disease had a mean age of (57.159.50) years; 80% were males and 20% were females; healthy volunteers had a mean age of (43.5610.52) years; 63% were females and 37% were males. Statistically, the cases group of CHD had a significantly higher rate of depressive disorder (50% vs. 0%) and a significantly higher rate of generalized anxiety disorder (37% vs. 0%) than the control healthy group. Manic episodes, hypomanic episodes, psychotic disorders, delusional disorders, panic disorders, and post-traumatic stress disorder were not significantly different between the CHD patients and control groups. Depressive Personality Disorder was also significantly less common in CHD patients than in the control group (P=0.026). Other personality abnormalities were not significantly different between the CHD sufferers and the healthy controls. The correlation between coronary heart disease and socioeconomic status and mental illness was examined in this research. CHD, PTSD, and other mental illnesses are discussed, along with their links to heart disease (PTSD
{"title":"A study of psychiatric disorders in a sample of patients with coronary heart disease","authors":"Mohamed EL-Hamady, S. Abd-Elmaksoud, Asmaa Mohamed, Nermeen Abdullah","doi":"10.21608/bjas.2023.237012.1251","DOIUrl":"https://doi.org/10.21608/bjas.2023.237012.1251","url":null,"abstract":": The focus here is on evaluating individuals with coronary heart disease from a psychological perspective. Outpatient clinics at Shebin Elkom teaching hospital and Benha University Hospital provided the sample of 400 participants; 200 patients with CHD and 200 healthy control volunteers were evaluated using the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID1) and the Structured Clinical Interview for DSM-IV Axis II Disorders (SCID11), respectively. Patients with coronary heart disease had a mean age of (57.159.50) years; 80% were males and 20% were females; healthy volunteers had a mean age of (43.5610.52) years; 63% were females and 37% were males. Statistically, the cases group of CHD had a significantly higher rate of depressive disorder (50% vs. 0%) and a significantly higher rate of generalized anxiety disorder (37% vs. 0%) than the control healthy group. Manic episodes, hypomanic episodes, psychotic disorders, delusional disorders, panic disorders, and post-traumatic stress disorder were not significantly different between the CHD patients and control groups. Depressive Personality Disorder was also significantly less common in CHD patients than in the control group (P=0.026). Other personality abnormalities were not significantly different between the CHD sufferers and the healthy controls. The correlation between coronary heart disease and socioeconomic status and mental illness was examined in this research. CHD, PTSD, and other mental illnesses are discussed, along with their links to heart disease (PTSD","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139312683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-27DOI: 10.21608/bjas.2023.240654.1264
Mohamed Mohamed, Mohamed El-Noury, Basma Sakr, Ahmed Ahmed
Background: Endometriomas are usually treated surgically using laparoscopic procedures, however the effect of various surgical methods on ovarian reserve is still being studied. The purpose of this research was to compare the effects on ovarian reserve (as determined by blood levels of AMH and AFC) between laparoscopic ovarian cystectomy and laparoscopic cyst de-roofing of endometriomas. The methods included testing 100 women who had been diagnosed with endometrioma. Patients were split into two groups: those who had laparoscopic ovarian cyst removal (N=50) and those who had laparoscopic cyst de-roofing (N=50). The results showed that the cystectomy group had considerably larger differences in terms of AMH, AFC, and ovarian volume. The two groups did not vary substantially in terms of either the mean difference or the mean difference percentage of the VAS. In instances with bilateral lesions, the AMH levels measured one month after cystectomy were considerably lower than those measured in the deroofing group. Ovarian volume was positively correlated with AMH, as was AFC and lesion size (p0.001). There were no statistically significant associations between age, body mass index, or VAS. There was a significant association between AMH level and lesion size, AFC, and ovarian volume, suggesting that laparoscopic cyst deroofing was less detrimental to ovarian reserve than cystectomy in instances of endometriomas. Endometriomas, laparoscopic ovarian cyst removal, laparoscopic cyst de-roofing, ovarian reserve, anti-mullerian hormone, and antral follicle count are some of the keywords that will be used
背景：子宫内膜异位症通常采用腹腔镜手术治疗，但各种手术方法对卵巢储备功能的影响仍在研究之中。这项研究的目的是比较腹腔镜卵巢囊肿切除术和腹腔镜子宫内膜异位症囊肿去顶术对卵巢储备功能的影响（由血液中的AMH和AFC水平决定）。研究方法包括对 100 名确诊患有子宫内膜异位症的妇女进行检测。患者被分为两组：腹腔镜卵巢囊肿切除术组（50 人）和腹腔镜囊肿去顶术组（50 人）。结果显示，囊肿切除术组在AMH、AFC和卵巢体积方面的差异要大得多。两组在 VAS 的平均差异或平均差异百分比方面差异不大。在双侧病变的病例中，膀胱切除术后一个月测得的 AMH 水平大大低于切除组。卵巢体积与 AMH 呈正相关，AFC 与病灶大小也呈正相关（P0.001）。年龄、体重指数或 VAS 之间没有明显的统计学关联。AMH水平与病灶大小、AFC和卵巢体积之间有明显的相关性，这表明在子宫内膜异位症的情况下，腹腔镜囊肿剥除术对卵巢储备功能的损害小于囊肿切除术。子宫内膜异位症、腹腔镜卵巢囊肿切除术、腹腔镜囊肿剥除术、卵巢储备功能、抗穆勒氏管激素和前卵泡计数是本研究将使用的关键词。
{"title":"The Impact of Laparoscopic Ovarian Cystectomy Versus Laparoscopic Deroofing upon Ovarian Reserve in Endometriomas","authors":"Mohamed Mohamed, Mohamed El-Noury, Basma Sakr, Ahmed Ahmed","doi":"10.21608/bjas.2023.240654.1264","DOIUrl":"https://doi.org/10.21608/bjas.2023.240654.1264","url":null,"abstract":"Background: Endometriomas are usually treated surgically using laparoscopic procedures, however the effect of various surgical methods on ovarian reserve is still being studied. The purpose of this research was to compare the effects on ovarian reserve (as determined by blood levels of AMH and AFC) between laparoscopic ovarian cystectomy and laparoscopic cyst de-roofing of endometriomas. The methods included testing 100 women who had been diagnosed with endometrioma. Patients were split into two groups: those who had laparoscopic ovarian cyst removal (N=50) and those who had laparoscopic cyst de-roofing (N=50). The results showed that the cystectomy group had considerably larger differences in terms of AMH, AFC, and ovarian volume. The two groups did not vary substantially in terms of either the mean difference or the mean difference percentage of the VAS. In instances with bilateral lesions, the AMH levels measured one month after cystectomy were considerably lower than those measured in the deroofing group. Ovarian volume was positively correlated with AMH, as was AFC and lesion size (p0.001). There were no statistically significant associations between age, body mass index, or VAS. There was a significant association between AMH level and lesion size, AFC, and ovarian volume, suggesting that laparoscopic cyst deroofing was less detrimental to ovarian reserve than cystectomy in instances of endometriomas. Endometriomas, laparoscopic ovarian cyst removal, laparoscopic cyst de-roofing, ovarian reserve, anti-mullerian hormone, and antral follicle count are some of the keywords that will be used","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139313087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-27DOI: 10.21608/bjas.2023.241600.1266
Asmaa Al Refaei, Yossra Mostafa, Karem Ibrahim
Background: Alopecia Alopecia areata (AA) is a non-scarring autoimmune condition that affects a large percentage of women. The most effective therapy is the intralesional administration of corticosteroids. The immunosuppressive action of the folic acid antagonist methotrexate is quite effective in individuals with severe AA. Hair follicles have high levels of vitamin D receptors, and keratinocytes must express these receptors to keep the hair growth cycle regular. Our goal is to learn more about the potential benefits of injecting Triamcinolone Acetonide (TrA), Methotrexate (MTX), and vitamin D3 directly into AA lesions. Intralesional injections of TrA, MTX, and vitamin D for the treatment of AA up to 2022 were studied by searching and analysing Medline databases (Pub Med and Medscape). The papers that were included in the meta-analysis were chosen based on a strict set of criteria. If they met any of the following criteria, we considered them for inclusion: First, it must be written in English. 2. Appear in journals with a strict peer review process. Third, analyse the benefits of injecting TrA, MTX, and vitamin D into the affected joint to treat AA. Extraction of Data: Research Studies were not included if they did not meet the inclusion criteria. The quality of a study may be determined by checking its ethical approval, eligibility criteria, controls, information, and evaluation methods. Our concerned research results were captured by independently abstracting data utilising a data collecting form from each qualifying study. We conclude that intralesional MTX and vitamin D3 may be safe and effective therapeutic alternatives to intralesional TrA for the treatment of localised AA in adult patients. Hair regrowth and the loss of AA-specific trichoscopic characteristics might both be detected at earlier stages thanks to trichoscopy's usefulness.
背景：斑秃（Alopecia areata，AA）是一种非瘢痕性自身免疫性疾病，女性患者占很大比例。最有效的治疗方法是鞘内注射皮质类固醇激素。叶酸拮抗剂甲氨蝶呤的免疫抑制作用对严重的 AA 非常有效。毛囊中含有大量的维生素 D 受体，角质形成细胞必须表达这些受体才能保持头发生长周期的正常。我们的目标是进一步了解直接向 AA 病灶注射曲安奈德（Triamcinolone Acetonide，TRA）、氨甲蝶呤（Methotrexate，MTX）和维生素 D3 的潜在益处。通过检索和分析 Medline 数据库（Pub Med 和 Medscape），研究了截至 2022 年用于治疗 AA 的曲安奈德、MTX 和维生素 D 的鞘内注射。纳入荟萃分析的论文是根据一套严格的标准筛选出来的。如果符合以下任何一项标准，我们就会考虑将其纳入：首先，必须用英语撰写。2.发表在有严格同行评审程序的期刊上。第三，分析向受累关节注射 TrA、MTX 和维生素 D 治疗 AA 的益处。提取数据：不符合纳入标准的研究未被纳入。一项研究的质量可通过检查其伦理批准、资格标准、控制、信息和评估方法来确定。我们的相关研究成果是通过使用每项合格研究的数据收集表独立摘录数据而获得的。我们的结论是，在治疗成年患者的局部 AA 时，鞘内注射 MTX 和维生素 D3 可能是鞘内注射 TrA 安全有效的替代疗法。由于毛发镜的作用，毛发再生和 AA 特异性毛发镜特征的丧失都可能在早期阶段被发现。
{"title":"Intralesional Injection of Triamcinolone Acetonide, Methotrexate and Vitamin D in Treatment of Alopecia Areata: A Narrative Review","authors":"Asmaa Al Refaei, Yossra Mostafa, Karem Ibrahim","doi":"10.21608/bjas.2023.241600.1266","DOIUrl":"https://doi.org/10.21608/bjas.2023.241600.1266","url":null,"abstract":"Background: Alopecia Alopecia areata (AA) is a non-scarring autoimmune condition that affects a large percentage of women. The most effective therapy is the intralesional administration of corticosteroids. The immunosuppressive action of the folic acid antagonist methotrexate is quite effective in individuals with severe AA. Hair follicles have high levels of vitamin D receptors, and keratinocytes must express these receptors to keep the hair growth cycle regular. Our goal is to learn more about the potential benefits of injecting Triamcinolone Acetonide (TrA), Methotrexate (MTX), and vitamin D3 directly into AA lesions. Intralesional injections of TrA, MTX, and vitamin D for the treatment of AA up to 2022 were studied by searching and analysing Medline databases (Pub Med and Medscape). The papers that were included in the meta-analysis were chosen based on a strict set of criteria. If they met any of the following criteria, we considered them for inclusion: First, it must be written in English. 2. Appear in journals with a strict peer review process. Third, analyse the benefits of injecting TrA, MTX, and vitamin D into the affected joint to treat AA. Extraction of Data: Research Studies were not included if they did not meet the inclusion criteria. The quality of a study may be determined by checking its ethical approval, eligibility criteria, controls, information, and evaluation methods. Our concerned research results were captured by independently abstracting data utilising a data collecting form from each qualifying study. We conclude that intralesional MTX and vitamin D3 may be safe and effective therapeutic alternatives to intralesional TrA for the treatment of localised AA in adult patients. Hair regrowth and the loss of AA-specific trichoscopic characteristics might both be detected at earlier stages thanks to trichoscopy's usefulness.","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139312983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-26DOI: 10.21608/bjas.2023.237321.1254
Mohamed Alsherbiny, Shreen Abu Alezz, Noha Ibrahim Elzaher
Background: The physiological process of ovarian aging is accompanied by a decrease in oocyte number & quality. Objectives: To compare the impact of PRP Injection alone & PRP with gonadotropins on ovarian Reserve in poor ovarian Responders (PORs) patients under laparoscope guidance. Patients & methods: This is Prospective controlled research, that had been carried at carried out at the obstetrics & gynecology department at Benha University from March 2023 till September 2023. 60 patients were included from the obstetrics & gynecology department at Benha University Hospital & some private centers. Patients from age 20 to 50 years old with poor ovarian responses participated and were separated into 2 groups, Group A & B. All underwent the laparoscopy for the procedure. Group A consists of thirty studied cases who received PRP Injection, and Group B consists of thirty studied cases who received PRP with gonadotropins. Results: There had been a high statistically significant variation among the 2 studied groups regarding FSH in the Sixth month. Also, there had been statistical variation among different periods in group A as regards AMH. There had been a high statistically significant variation between different periods in group B as regards AMH There had been statistically significant variation among 2 studied groups regarding Estradiol in the Sixth month . Conclusion: Women with premature ovarian insufficiency, particularly those who have tried unsuccessfully to conceive in the past, may benefit from intra-ovarian PRP injections because they are safe, effective, & all-natural
{"title":"Comparison between Laparoscopic intra-ovarian platelet rich plasma injection alone and with gonadotropins for ovarian rejuvenation","authors":"Mohamed Alsherbiny, Shreen Abu Alezz, Noha Ibrahim Elzaher","doi":"10.21608/bjas.2023.237321.1254","DOIUrl":"https://doi.org/10.21608/bjas.2023.237321.1254","url":null,"abstract":"Background: The physiological process of ovarian aging is accompanied by a decrease in oocyte number & quality. Objectives: To compare the impact of PRP Injection alone & PRP with gonadotropins on ovarian Reserve in poor ovarian Responders (PORs) patients under laparoscope guidance. Patients & methods: This is Prospective controlled research, that had been carried at carried out at the obstetrics & gynecology department at Benha University from March 2023 till September 2023. 60 patients were included from the obstetrics & gynecology department at Benha University Hospital & some private centers. Patients from age 20 to 50 years old with poor ovarian responses participated and were separated into 2 groups, Group A & B. All underwent the laparoscopy for the procedure. Group A consists of thirty studied cases who received PRP Injection, and Group B consists of thirty studied cases who received PRP with gonadotropins. Results: There had been a high statistically significant variation among the 2 studied groups regarding FSH in the Sixth month. Also, there had been statistical variation among different periods in group A as regards AMH. There had been a high statistically significant variation between different periods in group B as regards AMH There had been statistically significant variation among 2 studied groups regarding Estradiol in the Sixth month . Conclusion: Women with premature ovarian insufficiency, particularly those who have tried unsuccessfully to conceive in the past, may benefit from intra-ovarian PRP injections because they are safe, effective, & all-natural","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"06 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139313730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-25DOI: 10.21608/bjas.2023.236994.1250
Reda Khalil, A.M. Shaffik, Yasmien Mahmoud
Background: Awareness under general anaesthesia (AAGA) is still an uncommon yet worrying occurrence that might cause post-operative psychological anguish. The prevalence, risk factors, and preventative measures for AAGA are all investigated in depth in this research. Objective: This This review will describe the likelihood of consciousness while under general anaesthesia, and how to prepare for consciousness during surgery to reduce the risk of psychological complications after the procedure.. Conclusions: The best It seems that a dynamic mix of factors is the best technique for avoiding consciousness during anaesthesia. There are fewer preventative measures available during the emergence phase as compared to the induction and maintenance phases (e.g., use of short-acting BDZs in premedication to prevent AAWR at the induction). However, even at the emerging stage, there are very few practical ideas that may be especially successful at preventing this issue. The best method will include both the detection of high-risk patients and the implementation of suitable anaesthetic management measures. The use of instruments for monitoring and the cautious delivery of medications are examples of preventative measures. Neuromuscular monitoring by quantitative approaches is crucial since most instances of emerging consciousness can be related to a failure of neuromuscular recovery with a patient in complete recovery of consciousness.
{"title":"Updates in Awareness under General Anesthesia","authors":"Reda Khalil, A.M. Shaffik, Yasmien Mahmoud","doi":"10.21608/bjas.2023.236994.1250","DOIUrl":"https://doi.org/10.21608/bjas.2023.236994.1250","url":null,"abstract":"Background: Awareness under general anaesthesia (AAGA) is still an uncommon yet worrying occurrence that might cause post-operative psychological anguish. The prevalence, risk factors, and preventative measures for AAGA are all investigated in depth in this research. Objective: This This review will describe the likelihood of consciousness while under general anaesthesia, and how to prepare for consciousness during surgery to reduce the risk of psychological complications after the procedure.. Conclusions: The best It seems that a dynamic mix of factors is the best technique for avoiding consciousness during anaesthesia. There are fewer preventative measures available during the emergence phase as compared to the induction and maintenance phases (e.g., use of short-acting BDZs in premedication to prevent AAWR at the induction). However, even at the emerging stage, there are very few practical ideas that may be especially successful at preventing this issue. The best method will include both the detection of high-risk patients and the implementation of suitable anaesthetic management measures. The use of instruments for monitoring and the cautious delivery of medications are examples of preventative measures. Neuromuscular monitoring by quantitative approaches is crucial since most instances of emerging consciousness can be related to a failure of neuromuscular recovery with a patient in complete recovery of consciousness.","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139314160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
: Background: Hair The medical term for male pattern hair loss is androgenetic alopecia (AGA). Cells in the dermal papilla have been shown to be under oxidative stress in AGA patients. Paraoxonase 1 (PON1) is an important antioxidant that prevents oxidation of low-density lipoprotein (LDL) (LDL). Blood PON1 levels may be influenced by inflammation changes and oxidised LDL concentrations. The goal of this study was to compare the blood PON1 levels of male AGA patients with those of healthy controls. Discussion of Topics and Methods This study used a case-control design, with 60 male patients diagnosed with AGA and 20 age-and sex-matched healthy volunteers serving as cases and controls, respectively. People who went to Benha University Hospitals' Dermatology Outpatient Clinic between April 2020 and December 2021 were considered for inclusion. Serum PON1 and HDL levels were lower in AGA patients than in controls. Reduced levels of PON1 were seen in people with AGA, and oxidative stress was identified to be a possible cause. Androgenetic alopecia; paraoxonase 1 (PON1) in serum; male-pattern baldness.
{"title":"Evaluation of Paraoxonase 1 Serum Level in Male Androgenetic Alopecia Patients","authors":"Shimaa Desokey, Khaled Monib, Mohamed Hussein, Amira Mohamed","doi":"10.21608/bjas.2023.240521.1261","DOIUrl":"https://doi.org/10.21608/bjas.2023.240521.1261","url":null,"abstract":": Background: Hair The medical term for male pattern hair loss is androgenetic alopecia (AGA). Cells in the dermal papilla have been shown to be under oxidative stress in AGA patients. Paraoxonase 1 (PON1) is an important antioxidant that prevents oxidation of low-density lipoprotein (LDL) (LDL). Blood PON1 levels may be influenced by inflammation changes and oxidised LDL concentrations. The goal of this study was to compare the blood PON1 levels of male AGA patients with those of healthy controls. Discussion of Topics and Methods This study used a case-control design, with 60 male patients diagnosed with AGA and 20 age-and sex-matched healthy volunteers serving as cases and controls, respectively. People who went to Benha University Hospitals' Dermatology Outpatient Clinic between April 2020 and December 2021 were considered for inclusion. Serum PON1 and HDL levels were lower in AGA patients than in controls. Reduced levels of PON1 were seen in people with AGA, and oxidative stress was identified to be a possible cause. Androgenetic alopecia; paraoxonase 1 (PON1) in serum; male-pattern baldness.","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139313866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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