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Analysis of Capsaicinoids in Chilli Sauce with Ultra Fast Liquid Chromatography 超快速液相色谱法分析辣椒酱中的辣椒素
IF 0.3 Pub Date : 2022-12-16 DOI: 10.14235/bas.galenos.2022.50570
Burhan Ceylan, C. Önal, A. Önal
ABSTRACT
抽象
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引用次数: 0
Bond Strength of Different Composite Resin Materials and CAD/CAM Restorative Materials to Each Other and Dentin Tissue 不同复合树脂材料和CAD/CAM修复材料相互间及牙本质组织的结合强度
IF 0.3 Pub Date : 2022-12-16 DOI: 10.14235/bas.galenos.2022.54154
S. Saridag, N. Tekçe, Seval BAŞPINAR ALPER, Burcu DERELİ İNAN
ABSTRACT
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引用次数: 0
Sleep Habits and Quality of Life of Intellectually Disabled Children with and without Regular Physical Activity 有和没有规律体育活动的智障儿童的睡眠习惯和生活质量
IF 0.3 Pub Date : 2022-12-16 DOI: 10.14235/bas.galenos.2021.6090
Emine GÜDEK SEFEROĞLU, A. Gürol
ABSTRACT
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引用次数: 0
Relationship Between Toilet Type and Hemorrhoids 厕所类型与痔疮的关系
IF 0.3 Pub Date : 2022-10-07 DOI: 10.14235/bas.galenos.2022.60352
N. Uzun, Emine Yıldırım
ABSTRACT
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引用次数: 0
Can Dehydroepiandrosterone-Sulphate be a New Diagnostic Parameter in Idiopathic Hypogonadotropic Hypogonadism? 硫酸脱氢表雄酮能作为特发性促性腺功能减退症的新诊断指标吗?
IF 0.3 Pub Date : 2022-10-01 DOI: 10.14235/bas.galenos.2021.6094
K. Çadırcı, H. Keskin, Muharrem Bayrak, A. Çarlıoğlu, Şenay CEYLAN ARIKAN
Objective: Dehydroepiandrosterone (DHEA) and its sulfate derivative DHEA-sulfate (DHEA-s) are major androgen hormones which are synthesis from the adrenal origin. The purpose of this study was to investigate DHEA-s levels in male patients with idiopathic hypogonadotropic hypogonadism (IHH) and to determine whether DHEA-s level are a useful marker for diagnosis of IHH. Methods: A total of 91 subjects, 31 males with IHH (mean age 19.7±2.6 years) and 60 healthy males (mean age 20.7±2.6 years), were enrolled in this study. The patients with IHH were selected from the subjects who had not yet started treatment for hypogonadism and who had no additional disease, while the healthy control group consisted entirely from individuals admitted to the same hospital outpatient clinic for routine check-ups. Both groups’ blood sampling, anthropometric measures, and physical examination were undertaken Results: Mean DHEA-s level was 133.4±56.5 µg/dL in the IHH group and 433.3±160.3 µg/dL in the control group (p=0.000). The low DHEA-s level in patients with IHH was independent of age, cortisol, and adrenocorticotropic hormone (ACTH) at multivariate logistic regression analysis. The ROC analysis showed that DHEA-s ≤38.2 µg/dL supports a diagnosis of IHH with 100% specificity and 100% sensitivity. DHEA-s was as predictive as total testosterone which is used in the diagnosis of patients with IHH. Conclusion: DHEA-s level was significantly lower in the males with IHH compared to controls. Therefore, DHEA-s may be a potential predictive marker for diagnosis of IHH.
目的:脱氢表雄酮(DHEA)及其硫酸盐衍生物DHEA-s-是由肾上腺来源合成的主要雄激素。本研究的目的是研究特发性促性腺功能减退症(IHH)男性患者的DHEA-s水平,并确定DHEA-s水平是否是诊断IHH的有用标志物。方法:共有91名受试者参加本研究,其中31名IHH男性(平均年龄19.7±2.6岁)和60名健康男性(平均年纪20.7±2.6年)。IHH患者选自尚未开始性腺功能减退症治疗且没有其他疾病的受试者,而健康对照组完全由入住同一医院门诊进行常规检查的个体组成。结果:IHH组和对照组的平均DHEA-s水平分别为133.4±56.5µg/dL和433.3±160.3µg/dL(p=0.000)。在多变量逻辑回归分析中,IHH患者的低DHEA-s含量与年龄、皮质醇和促肾上腺皮质激素(ACTH)无关。ROC分析表明,DHEA-s≤38.2µg/dL支持诊断IHH,具有100%的特异性和100%的敏感性。DHEA-s与用于诊断IHH患者的总睾酮一样具有预测性。结论:男性IHH患者DHEA-s水平明显低于对照组。因此,DHEA-s可能是诊断IHH的一个潜在的预测标志物。
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引用次数: 0
Cancer Patients’ Knowledge of Exercise in Cancer: A Cross-sectional Study 癌症患者的运动知识:一项横断面研究
IF 0.3 Pub Date : 2022-10-01 DOI: 10.14235/bas.galenos.2021.6532
Ahsen Oğul, Sabriye Ercan
ÖZ Objective: Exercise is effective in reducing the risk of cancer, and treatment side effects. However, our empirical observations indicate that patients diagnosed with cancer have poor knowledge of exercise in cancer. This study aimed to evaluate cancer patients’ knowledge of exercise in cancer. Methods: After a review of the literature, the researchers developed a questionnaire aimed at evaluating knowledge of exercise in cancer. The study included patients with a history of cancer aged ≥18 years. The participants were asked to respond to each item in the electronic survey by selecting “I had no idea”, “I have heard of it”, or “I know very well”. Results: The study included a total of 125 participants with a history of cancer (75 females, 60%; 50 males, 40%), and their mean age was 52.05±11.50 years. We determined the validity and reliability of the questionnaire before analyzing participants' knowledge of exercise in cancer. Bartlett's test of sphericity and the Kaiser-Meyer-Olkin measure indicated that the data were appropriate for factor analysis (p<0.001). Factor analysis confirmed the structural validity of the questionnaire. Cronbach’s alpha was calculated as 0.963, implying reliable internal consistency. Subsequently, we analyzed participants’ answers to the questionnaire and observed that the response rate of “I know very well” ranged between 3.2% and 14.4% for different items. Conclusion: We prepared and validated a tool for the measurement of knowledge exercise i.e., patients diagnosed as having cancer. The sample size was calculated as five participants per item, that is 125 participants. The developed questionnaire can contribute to assess and improve knowledge of exercise among cancer patients.
ÖZ目的:运动可以有效降低癌症的风险,并治疗副作用。然而,我们的经验观察表明,被诊断为癌症的患者对癌症运动的了解很差。本研究旨在评估癌症癌症患者的运动知识。方法:在查阅文献后,研究人员编制了一份旨在评估癌症运动知识的问卷。该研究包括有癌症病史的患者,年龄≥18岁。参与者被要求对电子调查中的每个项目做出回答,选择“我不知道”、“我听说过”或“我非常清楚”。结果:该研究共包括125名有癌症病史的参与者(75名女性,60%;50名男性,40%),平均年龄为52.05±11.50岁。在分析参与者对癌症运动知识之前,我们确定了问卷的有效性和可靠性。Bartlett球度检验和Kaiser-Meyer-Olkin测量表明,这些数据适用于因子分析(p<0.001)。因子分析证实了问卷的结构有效性。Cronbachα的计算值为0.963,这意味着可靠的内部一致性。随后,我们分析了参与者对问卷的回答,发现不同项目的“我非常了解”回答率在3.2%至14.4%之间。结论:我们准备并验证了一种测量知识锻炼的工具,即诊断为癌症的患者。样本量计算为每个项目5名参与者,即125名参与者。开发的问卷有助于评估和提高癌症患者的运动知识。
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引用次数: 0
Can Anatomical Variations of AICA Loop be a Cause of Hearing Loss which can Affect the Laterality of Tinnitus Also? AICA环的解剖变异是否可能是听力损失的原因,从而影响耳鸣的侧边性?
IF 0.3 Pub Date : 2022-10-01 DOI: 10.14235/bas.galenos.2021.5843
E. TUNA YALÇINOZAN, Yasemin Küçükçiloğlu
Objective: We aimed to reveal whether the vascular loop variations created by the antero-inferior cerebellar artery (AICA) in the cerebellopontine angle (CPA) and the internal acoustic canal (IAC) can be a cause, that can affect laterality of tinnitus and cause hearing loss. Methods: The data and the magnetic resonance imaging scans were collected retrospectively and 109 patients with tinnitus were included in the study. Data were recorded according to the patients’ duration and laterality of tinnitus, laterality, type and frequency of hearing loss ,contact type and extension of AICA with remarking the side of the vascular loop. Results: A statistically significant difference was found in between the left ear high frequency (HF) hearing loss (p=0.042) and extension type of the AICA. Also showed statistically significant results in between left sided tinnitus (p=0.030) and the Chavda classification. Besides the patients who had right sided tinnitus, was found to be in relation with the right sided contact type as the p value was 0.023. Conclusion: Our results suggest that AICA variations in CPA and IAC can cause HF hearing loss as well as particularly affect the side of tinnitus. Nevertheless, this relationship must be confirmed by more advanced audiological and imaging techniques.
目的:我们旨在揭示小脑前下动脉(AICA)在桥小脑角(CPA)和内耳道(IAC)产生的血管环变化是否可能是影响耳鸣偏侧性并导致听力损失的原因。方法:回顾性收集资料和磁共振成像扫描,将109例耳鸣患者纳入研究。根据患者耳鸣的持续时间和偏侧性,听力损失的偏侧性、类型和频率,AICA的接触类型和延伸范围记录数据,并标记血管环的一侧。结果:左耳高频(HF)听力损失(p=0.042)和扩展型AICA之间存在统计学显著差异。在左侧耳鸣(p=0.030)和Chavda分类之间也显示出统计学上显著的结果。除右侧耳鸣患者外,发现与右侧接触型有关,p值为0.023。结论:我们的研究结果表明,CPA和IAC的AICA变化会导致HF听力损失,尤其是对耳鸣的影响。然而,这种关系必须通过更先进的听力学和成像技术来证实。
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引用次数: 0
Effect of Position Priority on Physiological Variables in Preterm Newborns Receiving Respiratory Support: Randomized Controlled Trial 体位优先对接受呼吸支持的早产儿生理变量的影响:随机对照试验
IF 0.3 Pub Date : 2022-10-01 DOI: 10.14235/bas.galenos.2021.6459
Sultan Beşi̇ktaş, E. Efe
ÖZ Objective: This study was designed to evaluate the effect of supine and prone position priority on oxygen saturation and heart rate in preterm newborns receiving respiratory support. Methods: This was a randomized controlled study. Preterm newborns who were aged <7 days, clinically stable and received respiratory support were included. The sample group consisted of 38 preterm newborns were divided into two groups by randomization according to position priority; Group 1 [supine/prone (S/P)], Group 2 [prone/supine (P/S)]. Results: In both prone and supine positions, the mean oxygen saturation of preterm newborns in Group 2 (P/S) was found to be significantly higher than those in Group 1 (S/P). It was determined that the mean heart rate of preterm newborns in Group 1 (S/P) in the supine position was significantly lower than in Group 2 (P/S). Conclusion: Giving the prone position first and then the supine position to preterm newborns receiving respiratory support increases oxygen saturation.
ÖZ目的:本研究旨在评价仰卧位和俯卧位优先对接受呼吸支持的早产儿血氧饱和度和心率的影响。方法:随机对照研究。纳入年龄<7天、临床稳定并接受呼吸支持的早产儿。样本组38例早产儿按体位优先顺序随机分为两组;1组[仰卧/俯卧(S/P)], 2组[俯卧/仰卧(P/S)]。结果:无论是俯卧位还是仰卧位,2组早产儿平均血氧饱和度(P/S)均明显高于1组(S/P)。结果表明,1组早产儿仰卧位平均心率(S/P)明显低于2组(P/S)。结论:对接受呼吸支持的早产儿,先俯卧后仰卧可提高血氧饱和度。
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引用次数: 0
Tobacco: Its Conventional and Modern Dosage Forms in Medication 烟草:传统和现代药物剂型
IF 0.3 Pub Date : 2022-10-01 DOI: 10.14235/bas.galenos.2021.6492
İmren Esentürk-Güzel, E. A. Yapar, R. Sindhu, Harnoor Kaur, Bilge Ahsen Kara
Tobacco is one of the most planted products in worldwide and the whole Nicotiana tabacum L. plant, its leaves, flowers, seeds or roots, and individual chemical compounds have medicinal uses such as as sedative, diuretic, or expectorant. From the past to the present, tobacco has been used in various dosage forms including oral/ transdermal films, sublingual tablets, mouth/nasal spray, and inhaler. In addition, Tobacco is a very valuable plant with uses in medicine and bioengineering applications. In this review, it was aimed to give information about the tobacco plant and its medicinal uses and also the pharmaceutical dosage forms as well as novel delivery systems of nicotine compound of tobacco via comprehensively search method of the literature by using Pubmed, ScienceDirect, ISI Web of Knowledge, and Google Scholar databases for articles published in peer-reviewed journals from mostly 2016 to 2021. It is also aimed to draw attention to the pharmaceutical use of tobacco plant instead of potential harmful uses. In conclusion, there is need to be carried out new studies to enlighten the exact mechanisms of tobacco and its major compound of nicotine on other diseases such as schizophrenia, Parkinson’s disease, and prose memory and attention than smoking cessation therapy and evaluate its safety and develop more effective novel pharmaceutical dosage forms.
烟草是世界上种植最多的产品之一,整个烟草(Nicotiana tabacum L.)植物,它的叶子、花、种子或根,以及个别化合物都有药用作用,如镇静、利尿剂或祛痰剂。从过去到现在,烟草以各种剂型使用,包括口服/透皮薄膜、舌下片剂、口腔/鼻喷雾剂和吸入器。此外,烟草是一种非常有价值的植物,可用于医药和生物工程。本综述利用Pubmed、ScienceDirect、ISI Web of Knowledge和谷歌Scholar数据库,对2016年至2021年发表在同行评议期刊上的文章进行文献综合检索,了解烟草植物及其药用价值,以及烟草尼古丁化合物的药物剂型和新型传递系统。它还旨在提请注意烟草植物的医药用途,而不是潜在的有害用途。总之,有必要开展新的研究,以揭示烟草及其主要化合物尼古丁对其他疾病如精神分裂症、帕金森病、散文记忆和注意力的确切机制,而不是戒烟治疗,并评估其安全性,开发更有效的新型药物剂型。
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引用次数: 0
The Effects of Surgical Timing on Treatment Outcomes in Carpal Tunnel Syndrome 手术时机对腕管综合征治疗效果的影响
IF 0.3 Pub Date : 2022-10-01 DOI: 10.14235/bas.galenos.2021.6714
Fatih Durgut, E. Şahin, M. S. Akar, A. Özdemir, Şeyhmus Yiğit
Objective: The purpose of this study is to assess and compare outcomes of two different timing surgery for moderately carpal tunnel syndrome (CTS). Methods: Eighty-eight patients who underwent early and late due to CTS were evaluated retrospectively. Patients with early surgery and late surgery were divided into two groups. Preoperative and postoperative visual analog scale (VAS) score and postoperative Boston Carpal Tunnel Questionnaire (BCTQ) scores of both groups were compared. Results: Preoperative and postoperative VAS scores were compared, there was a significant decrease in both groups. When BCTQ results of both groups were compared, the results of patients who underwent early surgery were statistically better. Conclusion: In conclusion, we think that early surgery is better clinically in patients with moderately CTS.
目的:本研究的目的是评估和比较两种不同时机手术治疗中度腕管综合征(CTS)的疗效。方法:对88例早期和晚期因CTS接受治疗的患者进行回顾性分析。早期手术和晚期手术的患者被分为两组。比较两组患者术前、术后视觉模拟量表(VAS)评分和术后波士顿腕管问卷(BCTQ)评分。结果:比较术前和术后VAS评分,两组均有明显下降。当比较两组的BCTQ结果时,接受早期手术的患者的结果在统计学上更好。结论:总之,我们认为早期手术治疗中度CTS在临床上更好。
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引用次数: 0
期刊
Bezmialem Science
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