Pub Date : 2007-01-01DOI: 10.1080/13590840701703918
P. Jolly, Yi Jiang, W. Ellis, R. Awuah, Jennifer A. M. Appawu, O. Nnedu, J. Stiles, Jia-Sheng Wang, O. Adjei, C. Jolly, Jonathan H. Williams
Purpose. We examined the relationship between various health parameters and aflatoxin B1 (AFB1) albumin adduct levels in plasma.Design. A cross‐sectional field study was conducted in four villages in the Ashanti region of Ghana.Methods. A survey on socio‐demographic and health characteristics was administered to 162 volunteers and blood (20 ml) was donated by 140 participants. AFB1 albumin adduct levels, liver function, hepatitis B and C viruses (HBV, HCV) and malaria infections were determined.Results. AFB1 levels ranged from 0.12 to 2.995 pmol mg−1 albumin (mean±standard deviation = 0.89±0.46) and was categorized based on the median as low (<0.80 pmol mg−1) or high (⩾0.80 pmol mg−1) and used in the analyses. By multivariate analysis, significantly higher levels of AFB1 were obtained for participants who reported symptoms of acute aflatoxicosis: history of yellow mouth (odds ratio = 5.5, confidence interval = 1.04–29.07, p = 0.04); history of sore swollen stomach (odds ratio = 4.54, confidence interval =...
{"title":"Association between aflatoxin exposure and health characteristics, liver function, hepatitis and malaria infections in Ghanaians","authors":"P. Jolly, Yi Jiang, W. Ellis, R. Awuah, Jennifer A. M. Appawu, O. Nnedu, J. Stiles, Jia-Sheng Wang, O. Adjei, C. Jolly, Jonathan H. Williams","doi":"10.1080/13590840701703918","DOIUrl":"https://doi.org/10.1080/13590840701703918","url":null,"abstract":"Purpose. We examined the relationship between various health parameters and aflatoxin B1 (AFB1) albumin adduct levels in plasma.Design. A cross‐sectional field study was conducted in four villages in the Ashanti region of Ghana.Methods. A survey on socio‐demographic and health characteristics was administered to 162 volunteers and blood (20 ml) was donated by 140 participants. AFB1 albumin adduct levels, liver function, hepatitis B and C viruses (HBV, HCV) and malaria infections were determined.Results. AFB1 levels ranged from 0.12 to 2.995 pmol mg−1 albumin (mean±standard deviation = 0.89±0.46) and was categorized based on the median as low (<0.80 pmol mg−1) or high (⩾0.80 pmol mg−1) and used in the analyses. By multivariate analysis, significantly higher levels of AFB1 were obtained for participants who reported symptoms of acute aflatoxicosis: history of yellow mouth (odds ratio = 5.5, confidence interval = 1.04–29.07, p = 0.04); history of sore swollen stomach (odds ratio = 4.54, confidence interval =...","PeriodicalId":88013,"journal":{"name":"Journal of nutritional & environmental medicine","volume":"16 1","pages":"242-257"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/13590840701703918","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"59779912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2007-01-01DOI: 10.1080/13590840701352807
L. Power
Purpose: The goal of this research was to determine patterns in adverse food reactions among human biotypes, if any.Design: Blood types A1, A2, B, AB, O and Rh‐negative were correlated to four kinds of food allergies and hypersensitivities.Materials and Methods: Three studies were conducted from 1985 to 2004. Blood types were correlated to food scores from: (1) mRAST‐IgE food allergy tests, (2) mRAST‐IgG food hypersensitivity tests, and (3) T‐cell food hypersensitivity tests (ELISA/ACT® LRA). An allergy history was recorded. Data were evaluated by statistical analyses, including: ANOVA, MANOVA, Mann–Whitney U, Kruskal–Wallis, and Chi Square. Clinical categories were established by means and ranges. (4) Blood‐type specific lectins were included from the scientific literature.Results: Results were reported by blood types and food groups as raw scores and classes, and included the following: blood type A1 reacted most strongly to nuts and beans, eggs, dairy, and nightshades; while type A2 reacted to the same...
{"title":"Biotype Diets System®: Blood types and food allergies","authors":"L. Power","doi":"10.1080/13590840701352807","DOIUrl":"https://doi.org/10.1080/13590840701352807","url":null,"abstract":"Purpose: The goal of this research was to determine patterns in adverse food reactions among human biotypes, if any.Design: Blood types A1, A2, B, AB, O and Rh‐negative were correlated to four kinds of food allergies and hypersensitivities.Materials and Methods: Three studies were conducted from 1985 to 2004. Blood types were correlated to food scores from: (1) mRAST‐IgE food allergy tests, (2) mRAST‐IgG food hypersensitivity tests, and (3) T‐cell food hypersensitivity tests (ELISA/ACT® LRA). An allergy history was recorded. Data were evaluated by statistical analyses, including: ANOVA, MANOVA, Mann–Whitney U, Kruskal–Wallis, and Chi Square. Clinical categories were established by means and ranges. (4) Blood‐type specific lectins were included from the scientific literature.Results: Results were reported by blood types and food groups as raw scores and classes, and included the following: blood type A1 reacted most strongly to nuts and beans, eggs, dairy, and nightshades; while type A2 reacted to the same...","PeriodicalId":88013,"journal":{"name":"Journal of nutritional & environmental medicine","volume":"16 1","pages":"125-135"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/13590840701352807","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"59779479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2007-01-01DOI: 10.1080/13590840601016387
M. Mohammad, L. Hussein, G. Yamamah, S. Rawi
Purpose. To assess the potential impact of probiotic and/or honey supplements on intestinal permeability among Egyptian children.Design. A randomized nutritional supplementation trial with a durati...
目的。评估益生菌和/或蜂蜜补充剂对埃及儿童肠道通透性的潜在影响。一项随机营养补充试验…
{"title":"The impact of probiotic and/or honey supplements on gut permeability among Egyptian children","authors":"M. Mohammad, L. Hussein, G. Yamamah, S. Rawi","doi":"10.1080/13590840601016387","DOIUrl":"https://doi.org/10.1080/13590840601016387","url":null,"abstract":"Purpose. To assess the potential impact of probiotic and/or honey supplements on intestinal permeability among Egyptian children.Design. A randomized nutritional supplementation trial with a durati...","PeriodicalId":88013,"journal":{"name":"Journal of nutritional & environmental medicine","volume":"16 1","pages":"10-15"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/13590840601016387","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"59778821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2005-12-01DOI: 10.1080/13590840600692964
J. Windsor, G. Rodway
{"title":"Weight loss at the extremes","authors":"J. Windsor, G. Rodway","doi":"10.1080/13590840600692964","DOIUrl":"https://doi.org/10.1080/13590840600692964","url":null,"abstract":"","PeriodicalId":88013,"journal":{"name":"Journal of nutritional & environmental medicine","volume":"40 1","pages":"228-229"},"PeriodicalIF":0.0,"publicationDate":"2005-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/13590840600692964","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"59778611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2005-03-01DOI: 10.1080/13590840500220197
Kanjana Suriyaprom, R. Tungtrongchitr, P. Pongpaew, B. Phonrat, T. Harnroongroj, N. Vudhivai, A. Tungtrongchitr, S. Paksanont, Somchai Pooudong, F. Schelp
Purpose. Cigarette smoking is considered to increase morbidity and the mortality risk of cardiovascular diseases. B vitamins regulate the metabolism of homocysteine via remethylation and trans‐sulfuration pathways. The purpose of this study was to investigate homocysteine concentrations, vitamin status, anthropometric and haematological measurements of healthy smokers compared with healthy non‐smoking subjects.Design. This cross‐sectional study was carried out among smokers and non‐smokers from suburban and urban residential areas in Bangkok, Thailand.Materials and methods. 174 smokers and 97 non‐smokers (aged 19–62), who participated voluntarily in the study, were investigated. Total homocysteine, folate, vitamin B2, B6, B12, and C concentrations were measured.Results. Total homocysteine concentrations in plasma were significantly higher in smokers than non‐smokers. Vitamin B2, folate, B12 and C concentrations were significantly lower among smokers than non‐smokers but vitamin B6 was not significantly di...
{"title":"Homocysteine and vitamin status in healthy Thai smokers","authors":"Kanjana Suriyaprom, R. Tungtrongchitr, P. Pongpaew, B. Phonrat, T. Harnroongroj, N. Vudhivai, A. Tungtrongchitr, S. Paksanont, Somchai Pooudong, F. Schelp","doi":"10.1080/13590840500220197","DOIUrl":"https://doi.org/10.1080/13590840500220197","url":null,"abstract":"Purpose. Cigarette smoking is considered to increase morbidity and the mortality risk of cardiovascular diseases. B vitamins regulate the metabolism of homocysteine via remethylation and trans‐sulfuration pathways. The purpose of this study was to investigate homocysteine concentrations, vitamin status, anthropometric and haematological measurements of healthy smokers compared with healthy non‐smoking subjects.Design. This cross‐sectional study was carried out among smokers and non‐smokers from suburban and urban residential areas in Bangkok, Thailand.Materials and methods. 174 smokers and 97 non‐smokers (aged 19–62), who participated voluntarily in the study, were investigated. Total homocysteine, folate, vitamin B2, B6, B12, and C concentrations were measured.Results. Total homocysteine concentrations in plasma were significantly higher in smokers than non‐smokers. Vitamin B2, folate, B12 and C concentrations were significantly lower among smokers than non‐smokers but vitamin B6 was not significantly di...","PeriodicalId":88013,"journal":{"name":"Journal of nutritional & environmental medicine","volume":"15 1","pages":"9-21"},"PeriodicalIF":0.0,"publicationDate":"2005-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/13590840500220197","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"59778224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2005-01-01DOI: 10.1080/13590840600554685
Jeremy H. Thompson, H. Anthony
In the UK, incinerators are still seen as a satisfactory answer to the problem of getting rid of the increasing quantities of waste, including increasing amounts of synthetics. This report examines the scientific evidence from all sources concerning the health implications of waste incineration, and its costs, explicit and hidden.The report reviews what is known about the range of pollutants released by incinerators and their health effects. The major air pollutants are fine airborne particulates (2.5 µm diameter and smaller), toxic metals, and organic chemicals. The precise content of the emissions varies with the material incinerated: emitted chemicals include persistent organic pollutants, hormone disrupters, and carcinogens, but not all the organic components have been identified. In addition, the ash produced includes large quantities of highly toxic fine fly ash (air pollution control residues), which pose important long‐term health risks.Dangers from chemicals have been overlooked in the past: chem...
{"title":"The health effects of waste incinerators","authors":"Jeremy H. Thompson, H. Anthony","doi":"10.1080/13590840600554685","DOIUrl":"https://doi.org/10.1080/13590840600554685","url":null,"abstract":"In the UK, incinerators are still seen as a satisfactory answer to the problem of getting rid of the increasing quantities of waste, including increasing amounts of synthetics. This report examines the scientific evidence from all sources concerning the health implications of waste incineration, and its costs, explicit and hidden.The report reviews what is known about the range of pollutants released by incinerators and their health effects. The major air pollutants are fine airborne particulates (2.5 µm diameter and smaller), toxic metals, and organic chemicals. The precise content of the emissions varies with the material incinerated: emitted chemicals include persistent organic pollutants, hormone disrupters, and carcinogens, but not all the organic components have been identified. In addition, the ash produced includes large quantities of highly toxic fine fly ash (air pollution control residues), which pose important long‐term health risks.Dangers from chemicals have been overlooked in the past: chem...","PeriodicalId":88013,"journal":{"name":"Journal of nutritional & environmental medicine","volume":"12 1","pages":"115-156"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/13590840600554685","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"59778139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2005-01-01DOI: 10.1080/13590840600681751
Michael Jenkins MSc Frcp, Margaret Rayman DPhil RPHNutr
Purpose. Previous studies on nutrient intake and status in chronic fatigue syndrome (CFS) were reviewed. Against this background, we investigated whether low mineral and B vitamin status in CFS patients was adequately explained by poor nutritional intake. Subsidiary aims were to explore the demographic, dietary, socio‐economic, psychological and general health profiles of CFS patients attending our clinics.Design. A cross‐sectional study of 51 CFS patients with biomarker values below the laboratory reference range for minerals and B vitamins.Materials and methods. Dietary and supplemented nutritional intakes were assessed for comparison with laboratory biomarkers in a hospital outpatient clinic.Results. Intakes below the UK reference nutrient intake, particularly of Ca and/or vitamin D, I and Se, were common among these patients. There was little correlation between intakes and biomarkers.Conclusions. Abnormal biomarkers may reflect underlying pathological processes rather than inadequate nutritional inta...
{"title":"Nutrient intake is unrelated to nutrient status in patients with chronic fatigue syndrome","authors":"Michael Jenkins MSc Frcp, Margaret Rayman DPhil RPHNutr","doi":"10.1080/13590840600681751","DOIUrl":"https://doi.org/10.1080/13590840600681751","url":null,"abstract":"Purpose. Previous studies on nutrient intake and status in chronic fatigue syndrome (CFS) were reviewed. Against this background, we investigated whether low mineral and B vitamin status in CFS patients was adequately explained by poor nutritional intake. Subsidiary aims were to explore the demographic, dietary, socio‐economic, psychological and general health profiles of CFS patients attending our clinics.Design. A cross‐sectional study of 51 CFS patients with biomarker values below the laboratory reference range for minerals and B vitamins.Materials and methods. Dietary and supplemented nutritional intakes were assessed for comparison with laboratory biomarkers in a hospital outpatient clinic.Results. Intakes below the UK reference nutrient intake, particularly of Ca and/or vitamin D, I and Se, were common among these patients. There was little correlation between intakes and biomarkers.Conclusions. Abnormal biomarkers may reflect underlying pathological processes rather than inadequate nutritional inta...","PeriodicalId":88013,"journal":{"name":"Journal of nutritional & environmental medicine","volume":"15 1","pages":"177-189"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/13590840600681751","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"59778306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2005-01-01DOI: 10.1080/13590840600692980
John A. A. Nichols Frcgp, Paul R. Grob Md Frcgp, N. Roche
Purpose. To determine what advice general practitioners (GPs) are giving on the health benefits of over‐the‐counter probiotics.Design. A web‐based questionnaire.Materials and methods. The questionnaire was posted on the website for the Southwest Thames Faculty of the Royal College of General Practitioners and letters were sent to all Surrey GPs, inviting them to take part. The questionnaire included a variety of clinical scenarios in which probiotic advice might be appropriate.Results. There was a 16.6% response rate. The value of taking probiotics with and after antibiotics was featured in one question and 72% of GPs were aware that this reduces the incidence of diarrhoea. Thirteen clinical scenarios were included in the questionnaire. Six scenarios involved patients taking antibiotics for various types of infection and seven scenarios described other conditions in which probiotic benefits have been claimed. GPs varied in their experience and opinion as to whether advice to take a probiotic would be appr...
{"title":"A web questionnaire to determine the advice general practitioners give on probiotics","authors":"John A. A. Nichols Frcgp, Paul R. Grob Md Frcgp, N. Roche","doi":"10.1080/13590840600692980","DOIUrl":"https://doi.org/10.1080/13590840600692980","url":null,"abstract":"Purpose. To determine what advice general practitioners (GPs) are giving on the health benefits of over‐the‐counter probiotics.Design. A web‐based questionnaire.Materials and methods. The questionnaire was posted on the website for the Southwest Thames Faculty of the Royal College of General Practitioners and letters were sent to all Surrey GPs, inviting them to take part. The questionnaire included a variety of clinical scenarios in which probiotic advice might be appropriate.Results. There was a 16.6% response rate. The value of taking probiotics with and after antibiotics was featured in one question and 72% of GPs were aware that this reduces the incidence of diarrhoea. Thirteen clinical scenarios were included in the questionnaire. Six scenarios involved patients taking antibiotics for various types of infection and seven scenarios described other conditions in which probiotic benefits have been claimed. GPs varied in their experience and opinion as to whether advice to take a probiotic would be appr...","PeriodicalId":88013,"journal":{"name":"Journal of nutritional & environmental medicine","volume":"15 1","pages":"212-222"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/13590840600692980","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"59778807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2005-01-01DOI: 10.1080/13590840600681827
M. Boris, Allan Goldblatt Pa‐C, S. Edelson
Purpose. Immune dysfunction has been associated with children with autism. One study found a beneficial response of intravenous gamma globulin (IVIG) therapy in autistic children. The present study further evaluated the administration of IVIG to these children.Design. This report shows the response of 26 autistic children who received IVIG over a 6 month period.Materials and methods. In documented autistic children, 400 mg kg−1 IVIG was administered each month for 6 months. Baseline and monthly Aberrant Behavior Checklists were completed on each child in order to measure the child's response to IVIG.Results. The participants' overall aberrant behaviors decreased substantially soon after receiving their first dose of IVIG. Further analysis of the total scores revealed decreases in hyperactivity, inappropriate speech, irritability, lethargy and stereotypy. However, 22 of the 26 children regressed to their pre‐IVIG status within 2–4 months of discontinuing the IVIG.Conclusions. Significant improvement occurr...
目的。免疫功能障碍与自闭症儿童有关。一项研究发现，静脉注射丙种球蛋白(IVIG)治疗自闭症儿童有有益的反应。本研究进一步评估了IVIG对这些儿童的应用。这份报告显示了26名接受IVIG治疗超过6个月的自闭症儿童的反应。材料和方法。在有记录的自闭症儿童中，每月给予400 mg kg - 1 IVIG，持续6个月。对每个儿童完成基线和每月异常行为检查表，以衡量儿童对ivig结果的反应。在接受第一剂IVIG后，参与者的总体异常行为显著减少。对总分的进一步分析显示，多动症、不恰当的言语、易怒、嗜睡和刻板印象都有所减少。然而，26名儿童中有22名在停用IVIG后的2-4个月内恢复到IVIG前的状态。显著改善发生…
{"title":"Improvement in children with autism treated with intravenous gamma globulin","authors":"M. Boris, Allan Goldblatt Pa‐C, S. Edelson","doi":"10.1080/13590840600681827","DOIUrl":"https://doi.org/10.1080/13590840600681827","url":null,"abstract":"Purpose. Immune dysfunction has been associated with children with autism. One study found a beneficial response of intravenous gamma globulin (IVIG) therapy in autistic children. The present study further evaluated the administration of IVIG to these children.Design. This report shows the response of 26 autistic children who received IVIG over a 6 month period.Materials and methods. In documented autistic children, 400 mg kg−1 IVIG was administered each month for 6 months. Baseline and monthly Aberrant Behavior Checklists were completed on each child in order to measure the child's response to IVIG.Results. The participants' overall aberrant behaviors decreased substantially soon after receiving their first dose of IVIG. Further analysis of the total scores revealed decreases in hyperactivity, inappropriate speech, irritability, lethargy and stereotypy. However, 22 of the 26 children regressed to their pre‐IVIG status within 2–4 months of discontinuing the IVIG.Conclusions. Significant improvement occurr...","PeriodicalId":88013,"journal":{"name":"Journal of nutritional & environmental medicine","volume":"15 1","pages":"169-176"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/13590840600681827","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"59778382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2005-01-01DOI: 10.1080/13590840500535313
S. Sadeghian, T. Neyestani, M. Shirazi, P. Ranjbarian
Background. Helicobacter pylori is one of the most prevalent gastric pathogens, causing gastric dysfunction, ulceration and, eventually, cancer. Antibiotic resistance, a rapidly growing problem, may interfere with the success of eradication therapy. The aim of this study was to evaluate the anti‐H. pylori effect of crude extracts derived from dill, fennel, caraway and cinnamon, all of which are common dietary additives in Iran.Design. In vitro bactericidal measures.Methods. The sensitivity of H. pylori isolates from gastric fluids to herbal extracts was evaluated using two standard ex vivo techniques.Results. The results showed that dill extract had the greatest antibacterial activity. Flow cytometric analysis of bacterial viability, however, demonstrated bacteriostatic properties of all test extracts.Conclusion. The possible synergistic effects of different dietary combinations of these extracts may be a factor in the possible protection afforded by the traditional Iranian diet against H. pylori infectio...
{"title":"Bacteriostatic effect of dill, fennel, caraway and cinnamon extracts against Helicobacter pylori","authors":"S. Sadeghian, T. Neyestani, M. Shirazi, P. Ranjbarian","doi":"10.1080/13590840500535313","DOIUrl":"https://doi.org/10.1080/13590840500535313","url":null,"abstract":"Background. Helicobacter pylori is one of the most prevalent gastric pathogens, causing gastric dysfunction, ulceration and, eventually, cancer. Antibiotic resistance, a rapidly growing problem, may interfere with the success of eradication therapy. The aim of this study was to evaluate the anti‐H. pylori effect of crude extracts derived from dill, fennel, caraway and cinnamon, all of which are common dietary additives in Iran.Design. In vitro bactericidal measures.Methods. The sensitivity of H. pylori isolates from gastric fluids to herbal extracts was evaluated using two standard ex vivo techniques.Results. The results showed that dill extract had the greatest antibacterial activity. Flow cytometric analysis of bacterial viability, however, demonstrated bacteriostatic properties of all test extracts.Conclusion. The possible synergistic effects of different dietary combinations of these extracts may be a factor in the possible protection afforded by the traditional Iranian diet against H. pylori infectio...","PeriodicalId":88013,"journal":{"name":"Journal of nutritional & environmental medicine","volume":"15 1","pages":"47-55"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/13590840500535313","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"59778473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：