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Review of Biotechnology and the Human Good 《生物技术与人类福祉评论》
Pub Date : 2008-04-09 DOI: 10.2202/1941-6008.1028
D. Resnik
Biotechnology and the Human Good by C. Ben Mitchell, Edmund D. Pellegrino, Jean Bethke Elshstain, and Scott B. Rae is a thoughtful, carefully argued perspective on the ethics of new developments in biotechnology, such as human enhancement, human germ-line engineering, cloning, nanotechnology, and cybernetics.
C. Ben Mitchell、Edmund D. Pellegrino、Jean Bethke Elshstain和Scott B. Rae合著的《生物技术与人类福祉》对生物技术的新发展,如人类增强、人类生殖系工程、克隆、纳米技术和控制论,提出了一个深思熟虑、仔细论证的观点。
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引用次数: 0
Death in Traffic: Why Are the Ethical Issues Ignored? 交通中的死亡:为什么伦理问题被忽视?
Pub Date : 2008-04-09 DOI: 10.2202/1941-6008.1014
L. Evans
More than a million people are killed on the world's roads annually. Injuries vastly outnumber deaths. The victims are overwhelmingly young and healthy prior to their crashes. This harm flows from many decisions made at many levels, from the individual road user to top government and industry leaders. While the decisions are steeped in a host of ethical questions, the ethical questions are almost universally ignored. This paper raises ethical issues relating to drivers, industry, and government. Increased professional and public focus on the ethical issues surrounding death and injury in traffic has the potential to generate enormous reductions in harm, far larger than those from ongoing safety programs.
世界上每年有一百多万人死于交通事故。受伤人数远远超过死亡人数。绝大多数受害者在车祸前都是年轻健康的。从个人道路使用者到政府高层和行业领导者,这种危害来自许多层面的许多决策。尽管决策中充斥着大量的伦理问题,但伦理问题几乎普遍被忽视。本文提出了与司机、行业和政府有关的伦理问题。专业人士和公众对交通事故中死亡和伤害的道德问题日益关注,有可能大大减少伤害,远远超过正在进行的安全项目。
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引用次数: 16
Alternative IP Mechanisms in Genomic Research 基因组研究中的替代IP机制
Pub Date : 2008-01-26 DOI: 10.2202/1941-6008.1052
C. Power, Edwin Levy, E. Marden, Ben Warren
This research is conducted by the Intellectual Property and Policy Research Group at the W. Maurice Young Centre for Applied Ethics at the University of British Columbia. It is part of the GE3LS (ethical, environmental, economic, legal and social issues related to genomics research) component of the Genome Canada Project "Dissecting Gene Expression Networks in Mammalian Organogenesis," MORGEN, which is located principally at the British Columbia Cancer Agency, Vancouver, British Columbia, Canada. The project is involved in upstream, basic genomic research. Part of this work includes the characterization of gene regulatory mechanisms governing organogenesis with a special focus on the heart, liver and pancreas. This paper serves as an introduction to both the MORGEN case study and the role of alternative mechanisms, such as open source. We discuss interim research results as they relate to our broader study of the relationship between open science, commercialization and technology transfer offices. The role of technology transfer offices (TTO) is central to our analysis and is viewed as a key factor in implementing Genome Canada policies and principles associated with IP and commercialization.
这项研究是由英属哥伦比亚大学w·莫里斯·杨应用伦理学中心的知识产权和政策研究小组进行的。它是加拿大基因组计划“剖析哺乳动物器官发生中的基因表达网络”(MORGEN)的GE3LS(与基因组学研究相关的伦理、环境、经济、法律和社会问题)组成部分的一部分,主要位于加拿大不列颠哥伦比亚省温哥华的不列颠哥伦比亚癌症机构。该项目涉及上游的基础基因组研究。这项工作的一部分包括控制器官发生的基因调控机制的特征,特别关注心脏,肝脏和胰腺。本文介绍了MORGEN案例研究和替代机制的作用,例如开放源代码。我们讨论中期研究结果,因为它们与我们对开放科学、商业化和技术转让办公室之间关系的更广泛研究有关。技术转移办公室(TTO)的作用是我们分析的核心,被视为实施加拿大基因组局与知识产权和商业化相关的政策和原则的关键因素。
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引用次数: 2
Questions of Human Enhancement: An Editorial 人类增强的问题:一篇社论
Pub Date : 2008-01-25 DOI: 10.2202/1941-6008.1033
A. M. Cutter, B. Gordijn
Introducing a special issue of a journal is a difficult, but pleasurable task for any editor. One must chose what to say about the themes of the issue, and how to introduce the papers presented. However, this task becomes still more complex when the special issue in question forms the inaugural issue of a new journal. This is the case here as we find ourselves introducing "Questions in Human Enhancement" as the inaugural issue of Studies in Ethics, Law and Technology. As such, this editorial serves two purposes: first we must introduce the journal itself, exploring our motivations for creating a new, quasi-open access, interdisciplinary publishing forum; and second we must introduce a stunning collection of comments, articles and discussion papers that have been written by a range of eminent scholars from across the globe.
对任何一个编辑来说,介绍一本期刊的特刊都是一件困难而又愉快的工作。一个人必须选择对这个问题的主题说些什么,以及如何介绍所提交的论文。然而,当所讨论的特刊成为新期刊的创刊号时,这项任务就变得更加复杂了。在《伦理、法律与技术研究》的创刊号中,我们引入了“人类增强的问题”。因此,这篇社论有两个目的:首先,我们必须介绍期刊本身,探索我们创建一个新的、准开放获取的跨学科出版论坛的动机;其次,我们必须介绍一个令人惊叹的评论、文章和讨论论文的集合,这些评论、文章和讨论论文是由来自世界各地的一系列著名学者撰写的。
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引用次数: 0
Go East? Multinational Companies in the Czech Life Sciences 去东吗?跨国公司在捷克生命科学
Pub Date : 2008-01-24 DOI: 10.2202/1941-6008.1048
S. Filippov, I. Costa
This article provides a qualitative analysis of the developments in the life sciences industry in Central and Eastern Europe and in the Czech Republic in particular. It begins by exploring the current state and the prospects of the life sciences industry in the region. Subsequently, it analyses the strategies of global multinational companies who are perceived to be the main driving force in the sector. In doing so, we follow the new stream in the international business literature and focus on the subsidiaries, rather than parent companies. Moreover, we specifically look at the subsidiaries possessing research capabilities. The transition dynamics and the membership in the European Union are helpful for this analysis. Finally the paper provides policy recommendations, arguing that more attention should be given to already established subsidiaries rather than pure attraction of new flows of foreign direct investment.
这篇文章提供了在生命科学产业发展的定性分析在中欧和东欧,特别是在捷克共和国。它首先探讨了该地区生命科学产业的现状和前景。随后,它分析了全球跨国公司的战略,这些公司被认为是该行业的主要推动力。在这样做的过程中,我们遵循国际商业文献中的新潮流,关注子公司,而不是母公司。此外,我们特别关注拥有研究能力的子公司。转型动态和欧盟成员国身份有助于这一分析。最后,本文提出了政策建议,认为应更多地注意已经建立的子公司,而不是单纯地吸引新的外国直接投资。
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引用次数: 1
Life Sciences Innovation in Central and Eastern Europe: Conceptual Frameworks and Contributions 中欧和东欧的生命科学创新:概念框架和贡献
Pub Date : 2008-01-24 DOI: 10.2202/1941-6008.1053
Farah Huzair, P. Robbins
This article outlines analytical frameworks for studying life sciences innovation in Central and Eastern Europe (CEE), based on national systems of innovation and the triple helix. The reflexive and evolutionary models of triple helix 1-3 help us in evaluating life sciences innovation in the shift from pre- to post-transition, and are useful in providing a systemic approach that emphasises social institutions over the role of the firm. While pre-transition CEE embodied a linear innovation model rooted in state ownership, after the transition we see the importance of the state as a network organiser, and the productive inputs of multinational corporations. Life sciences innovation in CEE is challenged by path dependency and institutional lock-in established through years of state control, from which it can be difficult to break out. Articles in this special issue highlight the benefits and constraints of new forms of private investment. While there is evidence for cautious optimism in the CEE pharmaceutical industry, quango-run state genome projects have been less successful. Findings on knowledge cultures in Hungarian agbiotech innovation communities help to flesh out the triple helix model. This issue also provides foresight in examining challenges of the central European pharmaceutical industry and open intellectual property regimes being trialed in Canada, which may have relevance for the region as post-transition innovation systems deepen.
本文概述了基于国家创新体系和三螺旋结构的中欧和东欧生命科学创新研究的分析框架。三螺旋1-3的反射和进化模型帮助我们评估从转型前到转型后的生命科学创新,并有助于提供一种强调社会制度而不是公司作用的系统方法。转型前的中东欧体现了植根于国有制的线性创新模式,而转型后,我们看到了国家作为网络组织者的重要性,以及跨国公司的生产性投入。中欧和东欧的生命科学创新受到路径依赖和多年来国家控制形成的制度锁定的挑战,很难从中挣脱出来。本期特刊的文章强调了新形式私人投资的好处和限制。尽管有证据表明中东欧制药业持谨慎乐观态度,但由半官方机构运营的国家基因组项目一直不太成功。匈牙利农业生物技术创新社区的知识文化研究结果有助于充实三螺旋模型。这一问题还为审查中欧制药业的挑战和加拿大正在试行的开放知识产权制度提供了远见,随着转型后创新体系的深化,这可能与该地区有关。
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引用次数: 3
Generous Funding for Interventive Aging Research Now? 介入性老龄化研究的慷慨资助?
Pub Date : 2008-01-16 DOI: 10.2202/1941-6008.1017
M. Häyry
This article examines Aubrey de Grey's case for allocating substantial funding to interventive biogerontological research immediately. The conclusion is that the case is inconclusive and that scientific analyses of costs and probabilities would be needed to defend it properly.
本文考察了奥布里·德·格雷(Aubrey de Grey)立即为干预性生物老年学研究分配大量资金的案例。结论是,该案件尚无定论,需要对成本和可能性进行科学分析,以适当地为其辩护。
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引用次数: 2
The Angelic Hierarchy: Aligning Ethical Push and Pull 天使等级:调整道德推与拉
Pub Date : 2008-01-16 DOI: 10.2202/1941-6008.1026
Mark Walker
A complementary `monetary' system is proposed: a computer-based system that allows us to assess the relative pro-community altruism of individuals. Such an arrangement could provide us with an alternate means of seeking social recognition than that offered by capitalism; specifically it offers the possibility of recognition based on altruistic contributions to society. This proposal promises several ethical advantages to our present social arrangements.
提出了一个补充的“货币”系统:一个基于计算机的系统,使我们能够评估个人的相对亲社区利他主义。这种安排可以为我们提供另一种寻求社会认可的方式,而不是资本主义提供的方式;具体来说,它提供了基于对社会无私贡献的认可的可能性。这个建议给我们目前的社会安排带来了几个伦理上的好处。
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引用次数: 1
Review of The Regulation of Cyberspace by Andrew Murray 安德鲁·默里《网络空间的监管》述评
Pub Date : 2008-01-09 DOI: 10.2202/1941-6008.1013
P. De Hert, E. Mantovani
After canvassing with good grace the make-up of cyberspace Andrew Murray wonders, in his recent book The Regulation of Cyberspace, which role traditional lawmakers are left to play in the new cyber-regulatory environment. Murray describes the static `command and control' regulatory model as disruptive and ineffective, and supports instead a dynamic, complimentary, and symbiotic regulatory model, which he presents under the features of an autopoietic environment and systems dynamics theory.Regulatory models, explains Andrew Murray in his recent book The Regulation of Cyberspace, intervene when a `disruptive innovation', such as the Internet, creates a regulatory vacuum. As cyberpaternalists suggest, however, the lack of traditional legal-regulatory control systems does not mean total freedom within cyberspace (p.203). On the contrary, as the author contends, `regulators of all forms rush to fill in this vacuum' so that the traditional regulatory mechanism is replaced by private regulatory systems acting, as Joel Reidenberg exposed, as `proxies' to the traditional regulatory system (i.e. courts and law enforcement authorities). Murray shares this point, but also gives credit to the views of cyberlibertarians. Cyberlibertarians argue that traditional command and control models are at last ineffective, even when they operate through proxies. In cyberspace, so they claim, regulators and regulatees mingle with each other to such an unheard-of extent that regulatory interventions cannot be effective unless regulatees co-operate actively.In his book, professor Andrew Murray treasures the sound arguments advanced by the cyberlibertarian and cyberpaternalist camps, and draws lessons from both in order to build a dialectic confrontation between static instrument and dynamic instrument thinking in the regulation of cyberspace. He consecrates the pars destruens of his work to explain why lawmakers should eschew the static approach and adheres to the pars construens to expand on a more dynamic and `smarter' regulatory model.
安德鲁•默里(Andrew Murray)在他的新书《网络空间的监管》(the Regulation of cyberspace)中,对网络空间的构成进行了一番优雅的考察后,他想知道传统立法者在新的网络监管环境中还能扮演什么角色。Murray将静态的“命令和控制”调节模式描述为破坏性的和无效的,并支持一种动态的、互补的和共生的调节模式,他在自创生环境和系统动力学理论的特征下提出了这种模式。安德鲁·默里在他的新书《网络空间的监管》中解释说,当互联网等“破坏性创新”造成监管真空时,监管模式就会进行干预。然而,正如网络家长主义者所建议的那样,缺乏传统的法律管制控制系统并不意味着网络空间内的完全自由(第203页)。相反,正如作者所主张的那样,“各种形式的监管机构都急于填补这一真空”,因此传统的监管机制被私人监管体系所取代,正如乔尔·雷登伯格所揭示的那样,作为传统监管体系(即法院和执法当局)的“代理人”。穆雷也认同这一点,但他也承认网络自由主义者的观点。网络自由主义者认为,传统的命令和控制模式最终是无效的,即使它们通过代理来运作。他们声称,在网络空间中,监管机构和被监管机构的相互融合达到了前所未有的程度,以至于除非监管机构积极合作,否则监管干预不可能有效。安德鲁·默里教授在其著作中,对网络自由主义和网络家长主义两大阵营提出的合理论点加以借鉴,试图在网络空间规制中构建一种静态工具思维和动态工具思维的辩证对抗。他将他的工作中的部分解释为解释为什么立法者应该避免静态方法,并坚持部分解释,以扩展更动态和“更聪明”的监管模式。
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引用次数: 0
The Legal and Ethical Changes in the NHS Landscape Accompanying the Policy Shift from Paper-Based Health Records to Electronic Health Records 随着从纸质健康记录到电子健康记录的政策转变,NHS环境中的法律和伦理变化
Pub Date : 2008-01-09 DOI: 10.2202/1941-6008.1010
A. Gillies
The introduction of IT into health and associated forms of care has changed the nature of risks associated with the use of information. Continuing development is increasing the rate of change. This paper will consider the relationship between policy, ethics and the law within this changing landscape using a risk management approach.The paper considers a 20 year time period from 1990 to 2010 and first maps out the landscape in terms of key shifts in policy. The article seeks to explore how the policy shifts have changed the legal and ethical implications of handling information, by addressing three specific questions:1. Do the policy changes following the 1997 General Election amount to a Kuhnian paradigm shift or simply an evolution?2. How have the legal and ethical implications of handling information been modified by changes in technology, policy and the law?3. How can the concept of opportunity risk help us understand the ethical implications of increased use of IT in health care?The article will conclude by identifying the legal and ethical challenges yet to come as the landscape continues to evolve.
将信息技术引入保健和相关形式的护理已经改变了与信息使用有关的风险的性质。持续的发展加快了变化的速度。本文将使用风险管理方法考虑在这种不断变化的环境中政策,道德和法律之间的关系。该论文考虑了从1990年到2010年的20年时间,并首先从政策的关键转变方面绘制了景观。本文试图通过解决三个具体问题来探讨政策转变如何改变了处理信息的法律和伦理含义:1。1997年大选后的政策变化是库恩范式的转变,还是仅仅是一种进化?技术、政策和法律的变化如何改变了处理信息的法律和伦理含义?机会风险的概念如何帮助我们理解在医疗保健中越来越多地使用信息技术的伦理影响?文章最后将指出,随着环境的不断发展,法律和道德方面的挑战尚未到来。
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引用次数: 6
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Studies in ethics, law, and technology
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