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VR Acrophobia Treatment - Development of Customizable Acrophobia Inducing Scenarios VR恐高症治疗-开发可定制的恐高症诱导场景
Pub Date : 2020-01-01 DOI: 10.2312/vcbm.20201171
Sebastian Wagner, K. Illner, Matthias Weber, B. Preim, P. Saalfeld
Specific phobias are among the most common mental diseases, affecting the lives of millions of people. Yet, many cases remain untreated and even undiagnosed, partly due to entry barriers such as waiting times and inconvenience of therapy. To improve the therapeutic options and convenience for the treatment of specific phobias, we implemented a virtual reality application for treating acrophobia (fear of heights) with in-virtuo exposure therapy. Our concept is based on principles from psychology and interaction design. This concept is then implemented using the game engine Unity and Oculus Rift headset as a target device for VR display. Our application has a wide range of customization options, which enables it to be personalized to individual patients. In addition, a number of motivational methods are integrated, which are intended to increase patient motivation, as motivation is essential for a successful therapy. CCS Concepts • Human-centered computing → Virtual reality; Interactive systems and tools; Visualization; • Applied computing → Health informatics;
特定恐惧症是最常见的精神疾病之一,影响着数百万人的生活。然而,许多病例仍未得到治疗,甚至未得到诊断,部分原因是等待时间和治疗不便等进入障碍。为了改善治疗选择和方便特定恐惧症的治疗,我们实施了一个虚拟现实应用程序,通过虚拟暴露疗法治疗恐高症(恐高)。我们的概念是基于心理学和交互设计的原则。然后使用游戏引擎Unity和Oculus Rift头显作为VR显示的目标设备来实现这一概念。我们的应用程序有广泛的定制选项,这使它能够个性化的个别患者。此外,还整合了一些激励方法,旨在增加患者的动机,因为动机对成功的治疗至关重要。•以人为本的计算→虚拟现实;互动系统和工具;可视化;•应用计算→卫生信息学;
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引用次数: 0
Analyzing Protein Similarity by Clustering Molecular Surface Maps 聚类分子表面图分析蛋白质相似性
Pub Date : 2020-01-01 DOI: 10.2312/vcbm.20201177
Karsten Schatz, Florian Friess, M. Schäfer, T. Ertl, M. Krone
Many biochemical and biomedical applications like protein engineering or drug design are concerned with finding functionally similar proteins, however, this remains to be a challenging task. We present a new imaged-based approach for identifying and visually comparing proteins with similar function that builds on the hierarchical clustering of Molecular Surface Maps. Such maps are two-dimensional representations of complex molecular surfaces and can be used to visualize the topology and different physico-chemical properties of proteins. Our method is based on the idea that visually similar maps also imply a similarity in the function of the mapped proteins. To determine map similarity we compute descriptive feature vectors using image moments, color moments, or a Convolutional Neural Network and use them for a hierarchical clustering of the maps. We show that image similarity as found by our clustering corresponds to functional similarity of mapped proteins by comparing our results to the BRENDA database, which provides a hierarchical function-based annotation of enzymes. We also compare our results to the TM-score, which is a similarity value for pairs of arbitrary proteins. Our visualization prototype supports the entire workflow from map generation, similarity computing to clustering and can be used to interactively explore and analyze the results. CCS Concepts • Human-centered computing → Dendrograms; Scientific visualization; • Applied computing → Bioinformatics; © 2020 The Author(s) Eurographics Proceedings © 2020 The Eurographics Association. DOI: 10.2312/vcbm.20201177 https://diglib.eg.org https://www.eg.org K. Schatz, F. Frieß, M. Schäfer, T. Ertl, and M. Krone / Analyzing Protein Similarity by Clustering Molecular Surface Maps
许多生物化学和生物医学应用,如蛋白质工程或药物设计,都涉及到寻找功能相似的蛋白质,然而,这仍然是一项具有挑战性的任务。我们提出了一种新的基于图像的方法来识别和视觉比较具有相似功能的蛋白质,该方法建立在分子表面图的分层聚类上。这种图谱是复杂分子表面的二维表示,可用于可视化蛋白质的拓扑结构和不同的物理化学性质。我们的方法是基于这样的想法,即视觉上相似的地图也意味着在绘制的蛋白质的功能上相似。为了确定地图的相似性,我们使用图像矩、颜色矩或卷积神经网络计算描述性特征向量,并将它们用于地图的分层聚类。通过将我们的结果与BRENDA数据库进行比较,我们发现通过聚类发现的图像相似性与映射蛋白质的功能相似性相对应,该数据库提供了基于分层功能的酶注释。我们还将我们的结果与tm分数进行了比较,tm分数是任意蛋白质对的相似性值。我们的可视化原型支持从地图生成、相似性计算到聚类的整个工作流程,并可用于交互式地探索和分析结果。•以人为中心的计算→树形图;科学可视化;•应用计算→生物信息学;©2020 The Author(s) Eurographics Proceedings©2020 The Eurographics Association。DOI: 10.2312 / vcbm。20201177 https://diglib.eg.org https://www.eg.org K. Schatz, F. Frieß, M. Schäfer, T. Ertl, M. Krone /聚类分子表面图分析蛋白质相似性
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引用次数: 1
VRIDAA: Virtual Reality Platform for Training and Planning Implantations of Occluder Devices in Left Atrial Appendages VRIDAA:用于训练和规划左心房附件闭塞装置植入的虚拟现实平台
Pub Date : 2020-01-01 DOI: 10.2312/vcbm.20201168
E. Medina, Ainhoa M. Aguado, Jordi Mill, X. Freixa, D. Arzamendi, C. Yagüe, O. Camara
Personalized anatomical information of the heart is usually obtained from the visual analysis of patient-specific medical images with standard multiplanar reconstruction (MPR) of 2D orthogonal slices, volume rendering and surface mesh views. Commonly, medical data is visualized in 2D flat screens, thus hampering the understanding of 3D complex anatomical details, including incorrect depth/scaling perception, which is critical for some cardiac interventions such as medical device implantations. Virtual reality (VR) is becoming a valid complementary technology overcoming some of the limitations of conventional visualization techniques and allowing an enhanced and fully interactive exploration of human anatomy. In this work, we present VRIDAA, a VR-based platform for the visualization of patient-specific cardiac geometries and the virtual implantation of left atrial appendage occluder (LAAO) devices. It includes different visualization and interaction modes to jointly inspect 3D LA geometries and different LAAO devices, MPR 2D imaging slices, several landmarks and morphological parameters relevant to LAAO, among other functionalities. The platform was designed and tested by two interventional cardiologists and LAAO researchers, obtaining very positive user feedback about its potential, highlighting VRIDAA as a source of motivation for trainees and its usefulness to better understand the required surgical approach before the intervention. CCS Concepts • Human-centered computing → Information visualization; • Applied computing → Interactive learning environments; Health care information systems;
个性化的心脏解剖信息通常是通过对患者特异性医学图像进行视觉分析,采用二维正交切片、体绘制和表面网格视图的标准多平面重建(MPR)。通常,医疗数据是在2D平面屏幕上可视化的,因此阻碍了对3D复杂解剖细节的理解,包括不正确的深度/缩放感知,这对于一些心脏干预措施(如医疗设备植入)至关重要。虚拟现实(VR)正在成为一种有效的补充技术,克服了传统可视化技术的一些局限性,并允许对人体解剖进行增强和完全互动的探索。在这项工作中,我们提出了VRIDAA,一个基于vr的平台,用于可视化患者特定心脏几何形状和左心房附件闭塞器(LAAO)装置的虚拟植入。它包括不同的可视化和交互模式,以联合检查3D LA几何形状和不同的LAAO设备,MPR 2D成像切片,与LAAO相关的几个地标和形态学参数等功能。该平台由两位介入心脏病专家和LAAO研究人员设计和测试,获得了非常积极的用户反馈,强调了VRIDAA作为学员的动力来源,以及它在干预前更好地了解所需手术方法的实用性。•以人为本的计算→信息可视化;•应用计算→交互式学习环境;卫生保健信息系统;
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引用次数: 7
GLANCE: Visual Analytics for Monitoring Glaucoma Progression GLANCE:用于监测青光眼进展的可视化分析
Pub Date : 2020-01-01 DOI: 10.2312/vcbm.20201175
Astrid van den Brandt, Mark Christopher, L. Zangwill, Jasmin Rezapour, C. Bowd, Sally L. Baxter, D. Welsbie, A. Camp, S. Moghimi, Jiun L. Do, R. Weinreb, Chris C. P. Snijders, M. A. Westenberg
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引用次数: 4
VirtualDSA++: Automated Segmentation, Vessel Labeling, Occlusion Detection and Graph Search on CT-Angiography Data virtualdsa++: ct血管造影数据的自动分割,血管标记,闭塞检测和图形搜索
Pub Date : 2020-01-01 DOI: 10.2312/vcbm.20201181
Florian Thamm, Markus Jürgens, H. Ditt, A. Maier
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引用次数: 6
Visual Analysis of Multivariate Intensive Care Surveillance Data 多变量重症监护监测数据的可视化分析
Pub Date : 2020-01-01 DOI: 10.2312/vcbm.20201174
N. Brich, C. Schulz, Jörg Peter, Wilfried Klingert, M. Schenk, D. Weiskopf, M. Krone
We present an approach for visual analysis of high-dimensional measurement data with varying sampling rates in the context of an experimental post-surgery study performed on a porcine surrogate model. The study aimed at identifying parameters suitable for diagnosing and prognosticating the volume state—a crucial and difficult task in intensive care medicine. In intensive care, most assessments not only depend on a single measurement but a plethora of mixed measurements over time. Even for trained experts, efficient and accurate analysis of such multivariate time-dependent data remains a challenging task. We present a linked-view post hoc visual analysis application that reduces data complexity by combining projection-based time curves for overview with small multiples for details on demand. Our approach supports not only the analysis of individual patients but also the analysis of ensembles by adapting existing techniques using non-parametric statistics. We evaluated the effectiveness and acceptance of our application through expert feedback with domain scientists from the surgical department using real-world data: the results show that our approach allows for detailed analysis of changes in patient state while also summarizing the temporal development of the overall condition. Furthermore, the medical experts believe that our method can be transferred from medical research to the clinical context, for example, to identify the early onset of a sepsis. CCS Concepts • Applied computing → Health care information systems; • Mathematics of computing → Time series analysis; Dimensionality reduction; • Human-centered computing → Information visualization; © 2020 The Author(s) Eurographics Proceedings © 2020 The Eurographics Association. DOI: 10.2312/vcbm.20201174 https://diglib.eg.org https://www.eg.org N. Brich et al. / Visual Analysis of Multivariate Intensive Care Surveillance Data
我们提出了一种在猪代孕模型上进行的实验性术后研究背景下,以不同采样率对高维测量数据进行视觉分析的方法。该研究旨在确定适合诊断和预测体积状态的参数,这是重症监护医学中至关重要和困难的任务。在重症监护中,大多数评估不仅依赖于单一的测量,而且随着时间的推移,还依赖于过多的混合测量。即使对于训练有素的专家来说,有效和准确地分析这种多变量时间相关数据仍然是一项具有挑战性的任务。我们提出了一个链接视图的事后可视化分析应用程序,通过将基于投影的时间曲线与小倍数的需求细节相结合,降低了数据的复杂性。我们的方法不仅支持个体患者的分析,而且通过使用非参数统计调整现有技术来支持整体分析。我们通过与外科领域科学家使用真实数据的专家反馈来评估我们的应用程序的有效性和接受度:结果表明,我们的方法允许详细分析患者状态的变化,同时也总结了整体状况的时间发展。此外,医学专家认为,我们的方法可以从医学研究转移到临床环境中,例如,识别败血症的早期发作。•应用计算→医疗保健信息系统;•计算数学→时间序列分析;降维;•以人为本→信息可视化;©2020 The Author(s) Eurographics Proceedings©2020 The Eurographics Association。DOI: 10.2312 / vcbm。20201174 https://diglib.eg.org https://www.eg.org N. Brich et al. /重症监护监测数据的可视化分析
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引用次数: 3
Robustness Evaluation of CFD Simulations to Mesh Deformation 网格变形CFD仿真的鲁棒性评价
Pub Date : 2019-01-01 DOI: 10.2312/vcbm.20191244
Alexander Scheid-Rehder, K. Lawonn, M. Meuschke
CFD simulations are an increasingly important method for the non-invasive analysis of risk factors for aneurysm rupture. Their robustness, however, has to be examined more thoroughly before clinical use is possible. We present a novel framework that enables robustness evaluation of CFD simulation according to mesh deformation on patient-specific blood vessel geometry. Our tool offers a guided workflow to generate, run, and visualize OpenFOAM simulations, which significantly decreases the usual overhead of CFD simulations with OpenFOAM. Besides, the deformation of the original geometry allows the user to evaluate the robustness of the simulation without the need to repeat expensive operations of the data pre-processing phase. We assessed the robustness of CFD simulations by applying our framework to several aneurysm data sets. CCS Concepts • Human-centered computing → Scientific visualization;
CFD模拟在动脉瘤破裂危险因素的无创分析中越来越重要。然而,在临床应用之前,必须对其稳健性进行更彻底的检查。我们提出了一种新的框架,可以根据患者特定血管几何形状的网格变形来评估CFD模拟的鲁棒性。我们的工具提供了一个指导工作流来生成、运行和可视化OpenFOAM模拟,这大大降低了使用OpenFOAM进行CFD模拟的通常开销。此外,原始几何形状的变形允许用户评估模拟的鲁棒性,而无需重复昂贵的数据预处理阶段的操作。我们通过将我们的框架应用于几个动脉瘤数据集来评估CFD模拟的稳健性。•以人为本的计算→科学可视化;
{"title":"Robustness Evaluation of CFD Simulations to Mesh Deformation","authors":"Alexander Scheid-Rehder, K. Lawonn, M. Meuschke","doi":"10.2312/vcbm.20191244","DOIUrl":"https://doi.org/10.2312/vcbm.20191244","url":null,"abstract":"CFD simulations are an increasingly important method for the non-invasive analysis of risk factors for aneurysm rupture. Their robustness, however, has to be examined more thoroughly before clinical use is possible. We present a novel framework that enables robustness evaluation of CFD simulation according to mesh deformation on patient-specific blood vessel geometry. Our tool offers a guided workflow to generate, run, and visualize OpenFOAM simulations, which significantly decreases the usual overhead of CFD simulations with OpenFOAM. Besides, the deformation of the original geometry allows the user to evaluate the robustness of the simulation without the need to repeat expensive operations of the data pre-processing phase. We assessed the robustness of CFD simulations by applying our framework to several aneurysm data sets. CCS Concepts • Human-centered computing → Scientific visualization;","PeriodicalId":88872,"journal":{"name":"Eurographics Workshop on Visual Computing for Biomedicine","volume":"44 5 1","pages":"189-199"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84071539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Layer-Aware iOCT Volume Rendering for Retinal Surgery 视网膜手术的分层感知iOCT体积绘制
Pub Date : 2019-01-01 DOI: 10.2312/vcbm.20191239
J. Weiss, U. Eck, M. A. Nasseri, M. Maier, A. Eslami, N. Navab
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引用次数: 6
A Web-based Application for the Visual Exploration of Colon Morphology Data 基于web的结肠形态数据可视化探索应用
Pub Date : 2019-01-01 DOI: 10.2312/VCBM.20191228
J. Males, E. Monclús, José Díaz, Pere-Pau Vázquez
The colon is an organ whose constant motility poses difficulties to its analysis. Although morphological data can be successfully extracted from Computational Tomography, its radiative nature makes it only indicated for patients with disorders. Only recently, acquisition techniques that rely on the use of Magnetic Resonance Imaging have matured enough to enable the generation of morphological colon data of healthy patients without preparation (i. e. administration of drugs or contrast agents). As a result, a database of colon morphological data for patients under different diets, has been created. Currently, the digestologists we collaborate with analyze the measured data of the gut by inspecting a set of spreadsheets. In this paper, we propose a system for the exploratory visual analysis of the whole database of morphological data at once. It provides features for the visual comparison of data correlations, the inspection of the morphological measures, as well 3D rendering of the colon segmented models. The system solely relies on the use of web technologies, which makes it portable even to mobile devices.
结肠是一个不断运动的器官,给分析它带来了困难。虽然形态数据可以成功地从计算机断层扫描中提取,但其辐射性质使其仅适用于患有疾病的患者。直到最近,依赖于使用磁共振成像的采集技术已经足够成熟,可以在没有准备(即给药或造影剂)的情况下生成健康患者的结肠形态数据。因此,建立了不同饮食下患者结肠形态数据的数据库。目前,与我们合作的消化学家通过检查一组电子表格来分析肠道的测量数据。在本文中,我们提出了一种对整个形态学数据数据库进行探索性可视化分析的系统。它提供了数据相关性的可视化比较,形态学测量的检查以及冒号分割模型的3D渲染的功能。该系统完全依赖于网络技术的使用,这使得它甚至可以移植到移动设备上。
{"title":"A Web-based Application for the Visual Exploration of Colon Morphology Data","authors":"J. Males, E. Monclús, José Díaz, Pere-Pau Vázquez","doi":"10.2312/VCBM.20191228","DOIUrl":"https://doi.org/10.2312/VCBM.20191228","url":null,"abstract":"The colon is an organ whose constant motility poses difficulties to its analysis. Although morphological data can be successfully extracted from Computational Tomography, its radiative nature makes it only indicated for patients with disorders. Only recently, acquisition techniques that rely on the use of Magnetic Resonance Imaging have matured enough to enable the generation of morphological colon data of healthy patients without preparation (i. e. administration of drugs or contrast agents). As a result, a database of colon morphological data for patients under different diets, has been created. Currently, the digestologists we collaborate with analyze the measured data of the gut by inspecting a set of spreadsheets. In this paper, we propose a system for the exploratory visual analysis of the whole database of morphological data at once. It provides features for the visual comparison of data correlations, the inspection of the morphological measures, as well 3D rendering of the colon segmented models. The system solely relies on the use of web technologies, which makes it portable even to mobile devices.","PeriodicalId":88872,"journal":{"name":"Eurographics Workshop on Visual Computing for Biomedicine","volume":"101 1","pages":"27-31"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73232425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A Visual Environment for Hypothesis Formation and Reasoning in Studies with fMRI and Multivariate Clinical Data 功能磁共振成像和多变量临床数据研究中假设形成和推理的视觉环境
Pub Date : 2019-01-01 DOI: 10.2312/vcbm.20191232
Daniel Jönsson, Albin Bergström, C. Forsell, Rozalyn Simon, M. Engström, A. Ynnerman, I. Hotz
We present an interactive visual environment for linked analysis of brain imaging and clinical measurements. The environment is developed in an iterative participatory design process involving neur ...
我们提出了一个交互式的视觉环境,用于脑成像和临床测量的关联分析。环境是在一个迭代的参与式设计过程中开发的,其中包括……
{"title":"A Visual Environment for Hypothesis Formation and Reasoning in Studies with fMRI and Multivariate Clinical Data","authors":"Daniel Jönsson, Albin Bergström, C. Forsell, Rozalyn Simon, M. Engström, A. Ynnerman, I. Hotz","doi":"10.2312/vcbm.20191232","DOIUrl":"https://doi.org/10.2312/vcbm.20191232","url":null,"abstract":"We present an interactive visual environment for linked analysis of brain imaging and clinical measurements. The environment is developed in an iterative participatory design process involving neur ...","PeriodicalId":88872,"journal":{"name":"Eurographics Workshop on Visual Computing for Biomedicine","volume":"46 1","pages":"57-68"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77682283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
期刊
Eurographics Workshop on Visual Computing for Biomedicine
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