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Pediatric Hypovolemic Shock 小儿低血容量性休克
Pub Date : 2013-02-22 DOI: 10.2174/1874309901307010010
M. Hobson, R. Chima
Hypovolemic shock is a common yet underappreciated insult which often accompanies illnesses afflicting children. Indeed, it is by far the most common type of shock in the pediatric age group worldwide. Early recognition and treatment of hypovolemic shock is paramount to reversing cellular hypoxia and ischemia before irreparable end-organ
低血容量性休克是一种常见但未被充分认识的侮辱,它经常伴随着折磨儿童的疾病。事实上,它是迄今为止世界范围内儿科年龄组中最常见的休克类型。早期识别和治疗低血容量性休克对于在终末器官不可修复前逆转细胞缺氧和缺血至关重要
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引用次数: 7
Prenatal and Postnatal Cell Phone Exposures and Headaches in Children. 产前和产后手机暴露与儿童头痛。
Pub Date : 2012-12-05 DOI: 10.2174/1874309901206010046
Madhuri Sudan, Leeka Kheifets, Onyebuchi Arah, Jorn Olsen, Lonnie Zeltzer

Objective: Children today are exposed to cell phones early in life, and may be at the greatest risk if exposure is harmful to health. We investigated associations between cell phone exposures and headaches in children.

Study design: The Danish National Birth Cohort enrolled pregnant women between 1996 and 2002. When their children reached age seven years, mothers completed a questionnaire regarding the child's health, behaviors, and exposures. We used multivariable adjusted models to relate prenatal only, postnatal only, or both prenatal and postnatal cell phone exposure to whether the child had migraines and headache-related symptoms.

Results: Our analyses included data from 52,680 children. Children with cell phone exposure had higher odds of migraines and headache-related symptoms than children with no exposure. The odds ratio for migraines was 1.30 (95% confidence interval: 1.01-1.68) and for headache-related symptoms was 1.32 (95% confidence interval: 1.23-1.40) for children with both prenatal and postnatal exposure.

Conclusions: In this study, cell phone exposures were associated with headaches in children, but the associations may not be causal given the potential for uncontrolled confounding and misclassification in observational studies such as this. However, given the widespread use of cell phones, if a causal effect exists it would have great public health impact.

目的:今天的儿童在生命早期接触手机,如果接触对健康有害,可能面临最大的风险。我们调查了儿童接触手机和头痛之间的关系。研究设计:丹麦国家出生队列纳入了1996年至2002年间的孕妇。当她们的孩子长到7岁时,母亲们完成了一份关于孩子健康、行为和暴露的调查问卷。我们使用多变量调整模型将仅产前、产后或产前和产后接触手机与儿童是否患有偏头痛和头痛相关症状联系起来。结果:我们的分析包括52680名儿童的数据。与没有接触手机的儿童相比,接触手机的儿童患偏头痛和头痛相关症状的几率更高。产前和产后暴露的儿童偏头痛的比值比为1.30(95%可信区间:1.01-1.68),头痛相关症状的比值比为1.32(95%可信区间:1.23-1.40)。结论:在这项研究中,手机暴露与儿童头痛有关,但考虑到在此类观察性研究中可能存在无法控制的混淆和错误分类,这种联系可能不是因果关系。然而,鉴于手机的广泛使用,如果存在因果关系,它将对公众健康产生巨大影响。
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引用次数: 35
Perceptions of the Sexual Assault Exam in the Emergency DepartmentSetting 在急诊科设置的性侵犯考试的看法
Pub Date : 2012-10-19 DOI: 10.2174/1874309901206010041
Ann Thomas, Michelle A. Lyn, A. Caviness, Deborah C. Hsu, X. Tran, A. Giardino
Objective: The purpose of this study is to determine how pediatric patients and/or their parents being interviewed and examined for suspected sexual assault perceive their experiences in the emergency department. Methods: A prospective study was conducted at an emergency department. A convenience sample was enrolled from September 2007 to February 2009. At the completion of the medical examination, patients and/or parents were asked to take part in a survey. Results: A total of 87 completed questionnaires were collected; 50 completed by parents/guardians and 37 completed by the patients; 14 patients had both parent and patient questionnaires completed. Of all 87 respondents, 74% of parents and 65% of the patients rated the overall quality of care as excellent, 90% of parents and 70.3% of patients rated the physician kindness as excellent, and 90% and 86.5% respectively rated the nurse kindness as excellent. Of the 50 patients, 35.1% patients found the exam sometimes or very painful and 40.5% found the exam scary sometimes to extremely scary. Patients who perceived the exam painful or scary did not rate their quality of medical care as lower than those who did not find the exam painful or scary, p=0.513 and p=0.800 respectively. Conclusions: Encouragingly, the emergency department environment did not cause higher levels of distress, anxiety or discomfort than other groups of patients evaluated in child abuse evaluation centers.
目的:本研究的目的是确定儿科患者和/或他们的父母被询问和检查涉嫌性侵犯如何看待他们在急诊科的经历。方法:在急诊科进行前瞻性研究。从2007年9月至2009年2月登记了方便样本。在体检完成后,要求患者和/或家长参加一项调查。结果:共回收问卷87份;50份由家长/监护人填写,37份由患者填写;14例患者完成了父母和患者的问卷调查。87名被调查者中,74%的家长和65%的患者认为整体护理质量为优秀,90%的家长和70.3%的患者认为医生的善良为优秀,90%和86.5%的患者认为护士的善良为优秀。在50例患者中,35.1%的患者认为考试有时或非常痛苦,40.5%的患者认为考试有时到非常可怕。认为考试痛苦或可怕的患者对医疗质量的评价并不低于没有感到考试痛苦或可怕的患者,p=0.513和p=0.800分别。结论:令人鼓舞的是,急诊科的环境并没有比在儿童虐待评估中心评估的其他组患者引起更高水平的痛苦、焦虑或不适。
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引用次数: 0
Targeting Asymptomatic Term and Late Preterm Newborns at Risk forEarly Sepsis: C Reactive Protein 20mg/L Threshold 针对有早期脓毒症风险的无症状足月和晚期早产儿:C反应蛋白20mg/L阈值
Pub Date : 2012-10-04 DOI: 10.2174/1874309901206010038
Margarida Ejarque-Albuquerque, Graça Oliveira, T. Santos, D. Rebelo, C. Moniz, T. Rodrigues
Identification of sepsis is a major issue due to limitations in diagnosis and severity of outcome. Different combinations of tests are used to screen babies at risk for infection, none specific enough to avoid treatment of non- infected newborns. 193 newborns with � 35 weeks of gestational age admitted in the maternity were screened for infection using a protocol scoring system involving haematological values and CRP � 10mg/l. Blood-cultures were taken after treatment decision, before antibiotics were started. No microbiological exam was included in the screening. Treatment decisions were taken by the staff irrespectively of the ongoing observational study. Newborns were classified by the authors in 4 groups: infected (culture verified), strongly suspected infection (SSI), no sepsis but treated (NST), no sepsis-no treatment (NSNT). Treatment decision was revaluated by the authors according to different cut-off levels of CRP. 40 newborns (20.7%) received antibiotics. 2 had positive blood-cultures. 13 were classified as SSI (all treated) and 178 as not infected (25 treated). All infected babies were identified but the error of the positive predictive value reached 62.5%. Revaluation of treatment decisions with CRP cut-off levels of 15, 20 and 25 mg/l showed respectively 60.5%, 51.6 and 48% of error of the positive predictive value, the first two cut-offs missing no infected newborns but the last one missing two. A new scoring system including CRP at 20mg/l has been in use since then without readmissions for infection and an estimated reduction of 24% antibiotic treatment.
由于诊断的局限性和结果的严重性,脓毒症的鉴定是一个主要问题。不同的检测组合被用来筛查有感染风险的婴儿,但没有一种检测的特异性足以避免对未感染的新生儿进行治疗。采用血液学指标和CRP - 10mg/l的方案评分系统对产妇入院的193例35周孕龄新生儿进行感染筛查。在决定治疗后,在开始使用抗生素之前进行血培养。筛查中不包括微生物学检查。治疗决定由工作人员做出,与正在进行的观察性研究无关。作者将新生儿分为4组:感染(培养证实)、强烈怀疑感染(SSI)、未脓毒症治疗(NST)、未脓毒症不治疗(NSNT)。根据不同的CRP临界值,作者重新评估治疗方案。40名新生儿(20.7%)接受抗生素治疗。2例血培养阳性。13例为SSI(全部治疗),178例为未感染(25例治疗)。所有感染婴儿均被识别,阳性预测值误差达62.5%。对CRP临界值为15、20、25 mg/l的治疗决策进行重估,阳性预测值的误差率分别为60.5%、51.6、48%,前两个临界值未遗漏感染新生儿,后两个临界值遗漏2例。从那时起,一种新的评分系统开始使用,包括20mg/l的CRP,没有因感染再入院,估计抗生素治疗减少了24%。
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引用次数: 0
Foreign Bodies in Non-Life Threatening Locations: A Risk Analysis ofNose and Ears Foreign Bodies in European Children 非危及生命部位的异物:欧洲儿童鼻子和耳朵异物的风险分析
Pub Date : 2012-05-04 DOI: 10.2174/1874309901206010023
D. Gregori, F. Foltran, G. Cuestas, H. Rodríguez, D. Passali, P. Berchialla
Children with a foreign body (FB) in either the ear or nose commonly present to the hospital. We present a retrospective series of 1186 European cases of FB in ears or nose in children younger 14 years old, classified following the International Classification of Disease (ICD931 and ICD932). Data were collected through a case report form (CRF) during three years (2000-2002) according to four main characteristics (socio-demographic, ergonomic, related to the hospital's management and to the circumstance of the injury). Overall, 610 (53%) sampled children were males. In 704 (71%) of cases, FBs were inorganic and among themabout 36% were balls, marbles or beads. The study investigates FBs featuresand injuries circumstances that are associated to prolonged hospitalization and complications. The most dangerous FBs resulted in objects with rigid or semi-rigid consistency.
患有耳或鼻异物(FB)的儿童通常会到医院就诊。我们报告了1186例欧洲14岁以下儿童耳鼻FB病例的回顾性研究,按照国际疾病分类(ICD931和ICD932)进行分类。通过病例报告表(CRF)在三年内(2000-2002年)根据四个主要特征(社会人口统计学、人体工程学、与医院管理有关以及与受伤情况有关)收集数据。总体而言,610名(53%)抽样儿童为男性。在704例(71%)中,FBs是无机的,其中约36%是球、弹珠或珠子。该研究调查了与长期住院和并发症相关的FBs特征和损伤情况。最危险的FBs导致物体具有刚性或半刚性一致性。
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引用次数: 5
Quality Control Techniques and Standards Implemented in the WEBBased“Susy Safe” Registry 在基于web的“Susy安全”注册表中实施的质量控制技术和标准
Pub Date : 2012-05-04 DOI: 10.2174/1874309901206010029
P. Berchialla, Arber Haxhiaj, D. Passali, H. Rodríguez, D. Gregori
The "Susy Safe" project is a European, WEB-based Registry (www.susysafe.org) aimed at collecting data regarding injuries caused by foreign bodies in the upper aero-digestive tract, occurred to children between 0 and 14 years of age. In most of the situations, injury registries are lacking an appropriate mechanism to control the data quality, mostly due to the low incidence of such events and to the corresponding high variability in the doctors reporting about the injury. In the Susy Safe registry, quality is a priority. Therefore, in order to monitor quality both automated and manual data inspections are used. There are automated checks which are based on classical data-entry controls and innovative statistical techniques mimicked from the industrial quality control. The manual inspections are conducted by dedicated medical doctors who check all cases that have an insufficient quality score obtained in the automated control. Having a centralized database and a Web access system, the quality control (QC) process becomes more flexible, improving its accuracy and reducing both the number of persons involved and the necessary time for its accomplishment.
“Susy Safe”项目是一个基于网络的欧洲注册项目(www.susysafe.org),旨在收集0至14岁儿童上消化道异物造成的伤害数据。在大多数情况下,损伤登记缺乏适当的机制来控制数据质量,主要是由于此类事件的发生率较低,以及相应的医生报告损伤的高度可变性。在Susy Safe注册表中,质量是优先考虑的。因此,为了监控质量,使用了自动和手动数据检查。有基于经典数据输入控制和模仿工业质量控制的创新统计技术的自动检查。人工检查由专门的医生进行,他们检查在自动控制中获得的质量分数不足的所有病例。有了集中的数据库和Web访问系统,质量控制(QC)过程变得更加灵活,提高了其准确性,减少了涉及的人员数量和完成质量控制所需的时间。
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引用次数: 0
Foreign Bodies Injuries in Children in Argentina: A CountrywideProgram Connecting Evidence with Prevention 阿根廷儿童的异物伤害:一项将证据与预防联系起来的全国性计划
Pub Date : 2012-05-04 DOI: 10.2174/1874309901206010016
H. Rodríguez, G. Cuestas, S. Ballali, G. Sica, Walter Widmann, Silvina Carca, Susana Tortosa, D. Gregori
The present study presents 441 cases of foreign bodies (FB) injuries collected in Argentina, in the framework of the Susy safe program, a web-based surveillance registry for foreign body injuries in children aged 0-14. The analysis was carried out on hospital cases recorded for foreign bodies' injuries, registered in the Susy Safe database and validated as proper for quality and consistency of data. The current analysis is carried out on FBs located in ears, nose, pharynx and larynx, trachea, bronchi and lungs, mouth, oesophagus and stomach. Injuries occurred most frequently in children older than 3 years Four-hundred-forty-four cases were treated: female patient's incidence was lower than males' one, with a 1:1.24 proportion (44.7% of female, and 55.3% males). Analyzing the outcomes, hospitalization was required in 218 cases (49.5%), most frequently when the injury occurred in trachea, bronchi and lungs (36.4%). Complications were recorded in 49 patients (11.1%), the majority of which (5.7%) presented to the ENT departments with a FB in the respiratory system. An adult was present in 77.8 % of the cases testifying that primary prevention has a key role in avoiding those kinds of injuries. Particularly, active strategies that promote behavior change seem to be necessary. A communication initiative is under development in Argentina, aimed at informing parents and supervisors of the risks posed by common objects to their children's health.
本研究介绍了在阿根廷收集的441例异物(FB)伤害,在Susy安全计划的框架内,这是一个基于网络的0-14岁儿童异物伤害监测登记。对医院记录的异物损伤病例进行了分析,这些病例已登记在Susy Safe数据库中,并经验证数据的质量和一致性是适当的。目前的分析是对位于耳、鼻、咽、喉、气管、支气管和肺、口腔、食道和胃的FBs进行的。3岁以上儿童损伤发生率最高,共444例,女性发生率低于男性,比例为1:1.24(女性占44.7%,男性占55.3%)。结果分析显示,218例(49.5%)患者需要住院治疗,其中以气管、支气管和肺部损伤最为常见(36.4%)。49例(11.1%)患者出现并发症,其中大多数(5.7%)因呼吸系统FB就诊于耳鼻喉科。77.8%的病例中有成年人在场,证明初级预防在避免这类伤害方面起着关键作用。特别是,促进行为改变的积极策略似乎是必要的。阿根廷正在制定一项宣传倡议,旨在向父母和监督者通报常见物品对其子女健康构成的风险。
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引用次数: 3
Editorial - Preventing Foreign Bodies Injuries in Children: the Italy-Argentina JointResearch Programme 2011-2013 社论-预防儿童异物伤害:意大利-阿根廷联合研究计划2011-2013
Pub Date : 2012-05-04 DOI: 10.2174/1874309901206010015
Ambassador Guido La Tella
The research on Preventing Foreign Bodies Injuries in children has been approved within the framework of the Executive Programme for 2011-2013 of the Agreement of Cultural, Scientific and Technological Cooperation between Italy and Argentina, signed in 1997 by the General Directorate for Cultural Cooperation of the Italian Ministry of Foreign Affairs (MAE) and the Ministry of Science, Teenology and Industrial Innovation of Argentina (Ministerio de Ciencia, Tecnología e Innovación Productiva MINCYT).
意大利外交部文化合作总局与阿根廷科学、技术和工业创新部(Ministerio de Ciencia)于1997年签署了《意大利与阿根廷文化、科学和技术合作协定》,在该协定2011-2013年执行方案的框架内批准了预防儿童异物伤害的研究。Tecnología e Innovación Productiva MINCYT)。
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引用次数: 0
A pilot study of the effects of an Australian centre-based early intervention program for children with autism 澳大利亚中心对自闭症儿童早期干预项目效果的初步研究
Pub Date : 2012-04-24 DOI: 10.2174/1874309901206010007
Jessica Paynter, James G. Scott, W. Beamish, Michael Duhig, H. Heussler
The current study sought to evaluate the effectiveness of an Australian centre-based early intervention program for children with autism. Outcomes for 10 children with autistic disorder aged between 32 and 65 months of age participating in the AEIOU early intervention program were investigated. Measures of educational, cognitive, and adaptive skills as well as autism symptoms were administered. Significant gains in educational skills in the areas of cognitive verbal/preverbal, fine motor and visual-motor imitation, motor domain score, and social reciprocity, were obtained as were decreases in autism symptoms. Limited evidence of gains was obtained for measures of cognitive or adaptive behaviour skills. This study provides promising preliminary evidence in support of the AEIOU program in terms of symptom reduction and increases in educational skills. Limitations and future research directions are discussed.
目前的研究试图评估澳大利亚中心对自闭症儿童早期干预项目的有效性。对10名年龄在32至65个月之间的自闭症儿童参与AEIOU早期干预项目的结果进行了调查。对教育、认知和适应技能以及自闭症症状进行了测量。在认知语言/言语前、精细运动和视觉运动模仿、运动领域得分和社会互惠等领域的教育技能显著提高,自闭症症状也有所减轻。在认知或适应性行为技能的测量中获得了有限的证据。这项研究为支持AEIOU项目在减轻症状和提高教育技能方面提供了有希望的初步证据。讨论了局限性和未来的研究方向。
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引用次数: 19
Five-Year Audit of Children Admitted to Hospital Under the Care ofPaediatricians in the North East of England 英格兰东北部儿科医生护理下入院儿童的五年审计
Pub Date : 2012-04-05 DOI: 10.2174/1874309901206010001
E. Strehle, C. Harker
Background: The aim of this survey was the evaluation of the case load of one hospital based paediatric team including inpatients, day care attenders and outpatients over a period of five and a half years. A further objective was the calculation of the generated income following the introduction of payment by results. Methods: Data were obtained from the hospital information technology and coding departments. They included age, gender, ethnicity, home postcode, month of attendance, length of inpatient stay and diagnosis. Analysis was performed using standard computer software. Results: Altogether, 9711 patients were assessed which generated an income of approximately 6 million pound sterling. Ninety percent of this amount resulted from inpatient work. The majority of patients were of white British origin, and their mean age was 4.1 years. The length of admission decreased from 1.5 days in 2005 to 0.7 days in 2010. Forty five percent of diagnoses were infections, mainly respiratory and gastrointestinal; and 55% had a non-infectious cause. The overall 'did not attend' rate was 25%. No deaths were recorded. Conclusion: The reduction of inpatient stay is a national phenomenon which supports the development of children's ambulatory care units. The reasons for the relatively high non-attendance rate are multi-factorial with family vulnerability being a contributory factor.
背景:本调查的目的是评估一家医院儿科小组的病例负荷,包括住院病人、日托护理人员和门诊病人,为期五年半。另一个目标是计算在实行按成绩付款制度后产生的收入。方法:从医院信息技术科和编码科获取数据。他们包括年龄、性别、种族、家庭邮政编码、就诊月份、住院时间和诊断。使用标准计算机软件进行分析。结果:总共评估了9711名患者,产生了大约600万英镑的收入。其中90%来自住院工作。大多数患者为英国白人,平均年龄为4.1岁。入院时间从2005年的1.5天减少到2010年的0.7天。45%的诊断为感染,主要是呼吸道和胃肠道感染;55%的人患有非传染性疾病。总体“未参加”的比例为25%。没有死亡记录。结论:住院时间的减少是一种全国性的现象,为儿童门诊的发展提供了支持。不出勤率较高的原因是多方面的,家庭脆弱性是一个因素。
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引用次数: 0
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The open pediatric medicine journal
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