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Nanoparticles: A Potential and Effective Method to Control Insect-Borne Diseases. 纳米颗粒:控制虫媒疾病的潜在有效方法。
IF 3.8 3区 化学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Pub Date : 2023-01-01 DOI: 10.1155/2023/5898160
Danyue Nie, Jiaqiao Li, Qinghua Xie, Lele Ai, Changqiang Zhu, Yifan Wu, Qiyuan Gui, Lingling Zhang, Weilong Tan

Insects act as vectors to carry a wide range of bacteria and viruses that can cause multiple vector-borne diseases in humans. Diseases such as dengue fever, epidemic encephalitis B, and epidemic typhus, which pose serious risks to humans, can be transmitted by insects. Due to the absence of effective vaccines for most arbovirus, insect control was the main strategy for vector-borne diseases control. However, the rise of drug resistance in the vectors brings a great challenge to the prevention and control of vector-borne diseases. Therefore, finding an eco-friendly method for vector control is essential to combat vector-borne diseases. Nanomaterials with the ability to resist insects and deliver drugs offer new opportunities to increase agent efficacy compared with traditional agents, and the application of nanoagents has expanded the field of vector-borne disease control. Up to now, the reviews of nanomaterials mainly focus on biomedicines, and the control of insect-borne diseases has always been a neglected field. In this study, we analyzed 425 works of the literature about different nanoparticles applied on vectors in PubMed around keywords, such as"nanoparticles against insect," "NPs against insect," and "metal nanoparticles against insect." Through these articles, we focus on the application and development of nanoparticles (NPs) for vector control, discussing the lethal mechanism of NPs to vectors, which can explore the prospect of applying nanotechnology in the prevention and control of vectors.

昆虫作为媒介携带多种细菌和病毒,可在人类中引起多种媒介传播疾病。登革热、流行性乙型脑炎和流行性斑疹伤寒等对人类构成严重威胁的疾病可通过昆虫传播。由于缺乏针对大多数虫媒病毒的有效疫苗,昆虫控制是病媒传播疾病控制的主要策略。然而,媒介生物耐药性的上升给媒介传播疾病的预防和控制带来了巨大的挑战。因此,寻找一种生态友好的病媒控制方法对于防治病媒传播的疾病至关重要。与传统药剂相比,具有抗虫和给药能力的纳米材料为提高药剂功效提供了新的机会,纳米药剂的应用扩大了媒介传播疾病控制的领域。到目前为止,对纳米材料的研究主要集中在生物医学领域,而虫媒疾病的防治一直是一个被忽视的领域。本研究围绕“纳米粒子抗虫”、“纳米粒子抗虫”、“金属纳米粒子抗虫”等关键词,对PubMed中425篇不同纳米粒子在载体上应用的文献进行分析。本文将重点介绍纳米颗粒在病媒生物防治中的应用与发展,探讨纳米颗粒对病媒生物的杀伤机制,为纳米技术在病媒生物防治中的应用前景提供参考。
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引用次数: 3
Grass-Shaped Zinc Oxide Nanoparticles Synthesized by the Sol-Gel Process and Their Antagonistic Properties towards the Biotrophic Parasite, Meloidogyne incognita. 溶胶-凝胶法制备草状氧化锌纳米颗粒及其对生物营养性寄生虫的拮抗性能
IF 3.8 3区 化学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Pub Date : 2023-01-01 DOI: 10.1155/2023/6834710
Amir Khan, Azmat Ali Khan, Mohd Jameel, Mohd Farhan Khan, Masudulla Khan, Arshad Khan, Faheem Ahmad, Mahboob Alam

The presence of Meloidogyne spp., also known as root-knot nematodes, presents a significant danger to global agricultural progress. Since chemical nematicides have high levels of toxicity, it is imperative to develop environmentally friendly methods to manage root-knot nematodes. Nanotechnology is now the most progressive way to attract researchers due to its innovative quality in combating plant diseases. Our study focused on the sol-gel process to synthesize grass-shaped zinc oxide nanoparticles (G-ZnO NPs) and assess its nematicidal behavior against Meloidogyne incognita. Various concentrations (250, 500, 750, and 1000 ppm) of G-ZnO NPs were utilized to expose both the infectious stage (J2s) and egg masses of M. incognita. Laboratory results revealed that G-ZnO NPs showed toxicity to J2s with LC50 values of 1352.96, 969.64, and 621.53 ppm at 12, 24, and 36 hours, respectively, and the result was the inhibition of egg hatching in M. incognita. All three exposure periods were reported linked with the concentration strength of G-ZnO NPs. The pot experiment results exhibited that G-ZnO NPs significantly reduced the root-gall infection of chickpea plants under M. incognita attack. Compared with the untreated control, there was a significant improvement in plant growth attributes and physiological parameters as well, when distinct G-ZnO NP doses (250, 500, 750, and 1000 ppm) were applied. In the pot study, we noticed a reduction in the root-gall index with an increase in the concentration of G-ZnO NPs. The results confirmed that G-ZnO NPs have enormous potential in sustainable agriculture for controlling the root-knot nematode, M. incognita, in chickpea production.

根结线虫(Meloidogyne spp.)也被称为根结线虫,对全球农业发展构成重大威胁。由于化学杀线虫剂具有很高的毒性,开发环境友好的方法来管理根结线虫势在必行。纳米技术由于其在对抗植物病害方面的创新性而成为目前吸引研究人员的最先进的方法。本文研究了溶胶-凝胶法制备草状氧化锌纳米颗粒(G-ZnO NPs),并对其杀线虫行为进行了研究。利用不同浓度(250、500、750和1000 ppm)的G-ZnO NPs暴露了无头野蝇的侵染期和虫卵。实验结果表明,G-ZnO NPs在12、24和36 h时对J2s的LC50值分别为1352.96、969.64和621.53 ppm,具有明显的抑卵作用。所有三个暴露期均与G-ZnO NPs的浓度强度有关。盆栽试验结果表明,G-ZnO NPs显著降低了豇豆根瘿侵染率。与未处理对照相比,施用不同剂量(250、500、750和1000 ppm)的G-ZnO NP对植株的生长特性和生理参数也有显著改善。在盆栽研究中,我们注意到根瘿指数随着G-ZnO NPs浓度的增加而降低。结果表明,G-ZnO NPs在控制鹰嘴豆生产中的根结线虫(M. incognita)方面具有巨大的可持续农业潜力。
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引用次数: 1
Bioinorganic Preparation of Hydroxyapatite and Rare Earth Substituted Hydroxyapatite for Biomaterials Applications. 羟基磷灰石的生物无机制备及稀土取代羟基磷灰石在生物材料中的应用。
IF 3.8 3区 化学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Pub Date : 2023-01-01 DOI: 10.1155/2023/7856300
Suha Q Al-Shahrabalee, Hussein Alaa Jaber
Rare Earth elements in the lanthanide series are regarded as one of the finest options for the cationic substitution of calcium ions in hydroxyapatite (HA) because of their favorable impact on the biological characteristics of substituted HA. Neodymium and cerium were used to substitute 5% of calcium ions in HA, prepared via the wet precipitation method. Characterization tests for pure and substituted HA were conducted using XRD, FTIR, EDS, and FESEM. The results showed that changing part from calcium ions in hydroxyapatite to Nd and Ce ions altered its structure, composition, and morphology. Regarding the biological tests, the cytotoxicity test revealed a change in IC50 for both normal and cancer cell lines, where substitution part of the Ca ions with rare Earth elements led to increasing antitumor activity in comparison with HA without substitution; in addition, antibacterial and fungicide activity was evident for both HA and Nd-Ce/HA, with a modest increase in antibacterial activity of Nd-Ce/HA against S. epidermidis and E. coli in comparison with HA. These findings may shed light on the process by which Nd and Ce ions improve the biological characteristics of pure HA and the increased potential of these bioceramics.
镧系稀土元素对羟基磷灰石(hydroxyapatite, HA)的生物学特性有良好的影响,被认为是羟基磷灰石(hydroxyapatite, HA)中钙离子阳离子取代的最佳选择之一。在湿沉淀法制备的透明质酸中,用钕和铈代替5%的钙离子。采用XRD、FTIR、EDS、FESEM等方法对纯HA和取代HA进行了表征。结果表明,将羟基磷灰石中的部分钙离子转变为Nd和Ce离子,改变了羟基磷灰石的结构、组成和形态。在生物学试验方面,细胞毒性试验显示正常细胞系和肿瘤细胞系的IC50都发生了变化,其中用稀土元素取代部分Ca离子比未取代的HA具有更高的抗肿瘤活性;此外,HA和Nd-Ce/HA均具有明显的抑菌和杀真菌活性,Nd-Ce/HA对表皮葡萄球菌和大肠杆菌的抑菌活性较HA略有提高。这些发现可能揭示了Nd和Ce离子改善纯HA生物特性的过程,以及这些生物陶瓷的潜力增加。
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引用次数: 3
Retracted: Research on Microseismic Source Location Method Based on Waveform Characteristics Monitored by Nanomaterial Sensor under the Background of Metal Oxide Polluted Environment. 金属氧化物污染环境下基于纳米材料传感器监测波形特征的微震源定位方法研究。
IF 3.8 3区 化学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Pub Date : 2023-01-01 DOI: 10.1155/2023/9840914
Bioinorganic Chemistry And Applications

[This retracts the article DOI: 10.1155/2022/5479007.].

[本文撤回文章DOI: 10.1155/2022/5479007]。
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引用次数: 0
Retracted: Development of Novel Bio-mulberry-Reinforced Polyacrylonitrile (PAN) Fibre Organic Brake Friction Composite Materials. 撤稿:新型生物桑葚增强聚丙烯腈(PAN)纤维有机制动摩擦复合材料的研制。
IF 3.8 3区 化学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Pub Date : 2023-01-01 DOI: 10.1155/2023/9897138
Bioinorganic Chemistry And Applications

[This retracts the article DOI: 10.1155/2022/6426763.].

[本文撤回文章DOI: 10.1155/2022/6426763.]。
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引用次数: 0
Bioinorganic Nanoparticles for the Remediation of Environmental Pollution: Critical Appraisal and Potential Avenues. 生物无机纳米颗粒修复环境污染:关键评价和潜在途径。
IF 3.8 3区 化学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Pub Date : 2023-01-01 DOI: 10.1155/2023/2409642
Md Mominur Rahman, Limon Ahmed, Fazilatunnesa Anika, Anha Akter Riya, Sumaiya Khatun Kali, Abdur Rauf, Rohit Sharma

Nowadays, environmental pollution has become a critical issue for both developed and developing countries. Because of excessive industrialization, burning of fossil fuels, mining and exploration, extensive agricultural activities, and plastics, the environment is being contaminated rapidly through soil, air, and water. There are a variety of approaches for treating environmental toxins, but each has its own set of restrictions. As a result, various therapies are accessible, and approaches that are effective, long-lasting, less harmful, and have a superior outcome are extensively demanded. Modern research advances focus more on polymer-based nanoparticles, which are frequently used in drug design, drug delivery systems, environmental remediation, power storage, transformations, and other fields. Bioinorganic nanomaterials could be a better candidate to control contaminants in the environment. In this article, we focused on their synthesis, characterization, photocatalytic process, and contributions to environmental remediation against numerous ecological hazards. In this review article, we also tried to explore their recent advancements and futuristic contributions to control and prevent various pollutants in the environment.

如今,环境污染已成为发达国家和发展中国家共同面临的严峻问题。由于过度工业化、燃烧化石燃料、采矿和勘探、广泛的农业活动和塑料,环境正在通过土壤、空气和水被迅速污染。治疗环境毒素的方法多种多样,但每种方法都有自己的一套限制。因此,各种治疗方法都是可获得的,并且广泛需要有效,持久,危害小且结果优越的方法。现代研究进展更多地集中在聚合物基纳米颗粒上,这些纳米颗粒经常用于药物设计、药物输送系统、环境修复、能量储存、转化等领域。生物无机纳米材料可能是控制环境污染物的较好候选材料。本文主要介绍了它们的合成、表征、光催化过程及其在环境修复中对多种生态危害的贡献。在这篇综述文章中,我们也试图探讨它们的最新进展和未来的贡献,以控制和预防各种环境污染物。
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引用次数: 4
Retracted: Assessing Deep Learning Techniques for the Recognition of Tropical Disease in Images from Parasitological Exams. 撤下:评估深度学习技术在寄生虫学检查图像中识别热带病。
IF 3.8 3区 化学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Pub Date : 2023-01-01 DOI: 10.1155/2023/9836730
Bioinorganic Chemistry And Applications

[This retracts the article DOI: 10.1155/2022/2682287.].

[此撤回文章DOI: 10.1155/2022/2682287.]。
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引用次数: 0
Metal Chelates of Sulfafurazole Azo Dye Derivative: Synthesis, Structure Affirmation, Antimicrobial, Antitumor, DNA Binding, and Molecular Docking Simulation. 磺胺呋唑偶氮染料衍生物的金属螯合物:合成、结构确认、抗菌、抗肿瘤、DNA结合及分子对接模拟。
IF 3.8 3区 化学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Pub Date : 2023-01-01 DOI: 10.1155/2023/2239976
Hoda A El-Ghamry, Rajaa O Al-Ziyadi, Fatmah M Alkhatib, Khadiga M Takroni, Abdalla M Khedr

A series of divalent and one trivalent metal chelates of the azo ligand resulting from coupling of sulfafurazole diazonium chloride with resorcinol have been designed and synthesized. Structure investigation of the isolated chelates have been achieved by applying spectroscopic and analytical tools which collaborated to assure the formation of the metal chelates in the molar ratios of 1L: 1M for Ni(II), Co(II), and Fe(III) chelates, where Cu(II) and Zn(II) complexes formed in the ratio 2L : 1M. The geometrical arrangement around the metal canters was concluded from UV-Vis spectra to be octahedral for all metal chelates. The attachment of the ligand to the metal ions took place through the azo group nitrogen and o-hydroxyl oxygen through proton displacement leading to the ligand being in monobasic bidentate binding mode. Antimicrobial and antitumor activities of the interested compounds have been evaluated against alternative microorganisms and cancer cells, respectively, in a trial to investigate their extent of activity in addition to docking studies. The mode of interaction of the compounds with SS-DNA has been examined by UV-Vis spectra and viscosity studies.

设计并合成了一系列由磺胺呋唑重氮氯与间苯二酚偶联而成的二价和一价三价偶氮配体金属螯合物。通过应用光谱和分析工具对分离的螯合物进行了结构研究,这些工具协作确保了Ni(II), Co(II)和Fe(III)螯合物以1L: 1M的摩尔比形成金属螯合物,其中Cu(II)和Zn(II)配合物以2L: 1M的摩尔比形成。紫外-可见光谱分析表明,金属螯合物在金属中心周围的几何排列为八面体。配体通过偶氮基团氮和邻羟基氧通过质子位移与金属离子结合,导致配体呈单碱双齿结合模式。除了对接研究外,我们还对感兴趣的化合物分别对替代微生物和癌细胞进行了抗菌和抗肿瘤活性评估,以研究它们的活性程度。通过紫外可见光谱和黏度研究考察了化合物与SS-DNA的相互作用模式。
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引用次数: 3
Retracted: Clinical Diagnostic Value of Quantitative Hepatitis B Virus Core Antibody Test in Chronic Viral Hepatitis B. 乙型肝炎病毒核心抗体定量检测对慢性乙型肝炎的临床诊断价值。
IF 3.8 3区 化学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Pub Date : 2023-01-01 DOI: 10.1155/2023/9857473
Bioinorganic Chemistry And Applications

[This retracts the article DOI: 10.1155/2021/3720571.].

[本文撤回文章DOI: 10.1155/2021/3720571]。
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引用次数: 0
Retracted: A Study on Glycyrrhiza glabra-Fortified Bread: Predicted Glycemic Index and Bioactive Component. 撤下:甘草强化面包的研究:预测血糖指数和生物活性成分。
IF 3.8 3区 化学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Pub Date : 2023-01-01 DOI: 10.1155/2023/9828939
Bioinorganic Chemistry And Applications

[This retracts the article DOI: 10.1155/2022/4669723.].

[本文撤回文章DOI: 10.1155/2022/4669723.]。
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引用次数: 0
期刊
Bioinorganic Chemistry and Applications
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