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One- or Two- Levels Treatment by Arthroplasty of Cervical Degenerative Disease. Preliminary Results after 5 Years Postoperative Controls 颈椎退行性疾病关节置换术的一级或二级治疗。术后5年对照的初步结果
Pub Date : 2018-01-06 DOI: 10.4172/2165-7939.1000405
P. Fransen, D. Noriega, A. Chatzisotiriou, Pointillart
Introduction: Although cervical arthroplasties have been widely used with some success over the last decade, long terms results are missing, particularly for the latest designed implants such as semi constrained prostheses. Material and methods: 89 patients were enrolled in an observational study evaluating long term safety and potential complications related to the use of the cervical prosthesis Baguera® C. All patients had been treated at one or two levels between June 2009 and June 2011. At the 5 years FU visit, the patients were evaluated clinically and neurologically, and with self-assessment questionnaires (NDI, SF12). Radiological examination was performed by lateral X-rays in neutral, flexion and extension positions. Results: There were no reoperations at the arthroplasty level, no fracture of system components, no loss of fixation, and no migration nor subsidence. 17 patients had signs of adjacent level(s) degeneration. The performance related to Baguera®C usage, was evaluated at 5+ Y. PO by three parameters: Range of Motion (ROM), NDI and SF-12 scores. ROM at the treated level was 8.6° ± 5.0°. 87.7% of the treated levels showed preserved motion. NDI score was 19.5% ± 14.1%. 92% of the subjects reported NDI scores over 50%, and 74.2% of the subjects reported NDI scores under 30% and 45% of the subjects reported NDI scores under 10%. The QOL Index and Patient Satisfaction (SF-12 scores) reached 48.5 ± 8.6 for the PCS physical score and 48.0 ± 10.5 for the MCS Mental score. Both SF-12 components, physical and mental, were close to a normal health status (50%). Conclusion: Cervical disc replacement with the Baguera®C prosthesis shows excellent safety, clinical results and long-term motion preservation. There was no index or adjacent level reoperation after 5 years. Radiological progression of adjacent level degeneration was seen in a significant minority of cases, but without clinical expression.
引言:尽管在过去的十年里,颈关节置换术已经得到了广泛的应用,并取得了一些成功,但长期的结果是缺失的,特别是对于最新设计的植入物,如半约束假体。材料和方法:89名患者参加了一项观察性研究,该研究评估了与使用Baguera®C宫颈假体相关的长期安全性和潜在并发症。所有患者在2009年6月至2011年6月期间都接受了一到两个级别的治疗。在5年的FU访视中,对患者进行临床和神经病学评估,并使用自我评估问卷(NDI,SF12)。放射检查是在中立、屈曲和伸展位置进行横向X光检查。结果:在关节成形术水平上没有再次手术,没有系统部件骨折,没有固定丢失,没有移位或下沉。17名患者有邻近级别退化的迹象。与Baguera®C使用相关的性能在5+Y.PO时通过三个参数进行评估:运动范围(ROM)、NDI和SF-12分数。ROM在处理水平为8.6°±5.0°。87.7%的处理水平显示出保持运动。NDI评分为19.5%±14.1%。92%的受试者报告NDI评分超过50%,74.2%的受试人员报告NDI得分低于30%,45%的受试人报告NDI分数低于10%。PCS物理评分的生活质量指数和患者满意度(SF-12评分)达到48.5±8.6,MCS心理评分达到48.0±10.5。SF-12的两个组成部分,身体和精神,都接近正常健康状态(50%)。结论:Baguera®C人工颈椎间盘置换术具有良好的安全性、临床效果和长期的运动保护作用。5年后没有任何指标或邻近级别的再次手术。在极少数病例中可见邻近级别退行性变的放射学进展,但没有临床表现。
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引用次数: 2
Surgical Technique of Endoscopic Transforaminal Decompression and Fusion with a Threaded Expandable Interbody Fusion Cage and A Report of 24 Cases 内镜下椎间孔减压融合带螺纹可扩椎间融合器手术技术附24例报告
Pub Date : 2018-01-01 DOI: 10.4172/2165-7939.1000409
K. Lewandrowski
Fusion of the anterior column with placement of interbody fusion cages is commonly employed in the treatment of instability-related degenerative disc disease that has been proven refractory in non-operative treatment. Interbody fusion cages aid in the containment of bone graft, promotion of more reliable fusion, and restoration of neuroforaminal height. The VariLift® Interbody Fusion System (VariLift® system) has been developed as a standalone solution to address subsidence and migration problems seen with traditional lumbar interbody fusion cages that require posterior supplemental transpedicular screw fixation for improved stability. This series of 24 consecutive patients describes patient selection criteria and the technical aspects of this novel endoscopic transforaminal lumbar interbody fusion technique in a step-by-step fashion. The transforaminal endoscopically assisted interbody fusion with the standalone expandable VariLift® system represents a simplified alternative to other pedicle screw-based spinal fusion.
前柱融合置入椎体间融合器通常用于治疗非手术治疗难治的不稳定相关性退变性椎间盘疾病。椎间融合笼有助于遏制植骨,促进更可靠的融合,并恢复神经间孔高度。VariLift®椎体间融合系统(VariLift®系统)是一种独立的解决方案,用于解决传统腰椎椎体间融合器出现的下沉和移动问题,这些问题需要后路辅助经椎弓根螺钉固定以提高稳定性。这一系列连续的24例患者逐步描述了患者的选择标准和这种新型经椎间孔内窥镜腰椎体间融合技术的技术方面。经椎间孔内窥镜辅助椎体间融合与独立可扩展VariLift®系统代表了其他椎弓根螺钉脊柱融合的简化替代方案。
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引用次数: 12
Dynamic Radiographs Not Always Essential in Diagnosis of Lumbar Spinal Instability 动态x线片并不总是诊断腰椎不稳定的必要条件
Pub Date : 2018-01-01 DOI: 10.4172/2165-7939.s7-017
Ping Yen Yeo, Aravind Kumar
Objective: Dynamic radiographs are widely used to assess radiological spinal instability. The authors aim to compare the sensitivity of dynamic radiographs versus spontaneous reduction seen on magnetic resonance imaging when compared to a standing lateral radiograph in diagnosing instability. Materials and Methods: This study is a retrospective review of 75 patients from a single center with suspected clinical lumbar spinal instability presenting with back and/or leg pain and had undergone a magnetic resonance imaging of their lumbosacral spine as well as a lumbar radiograph series. The authors compared the criterion sensitivity (in accordance to Posner criteria) of dynamic radiographs versus magnetic resonance imaging. Pearson's chi-square test was used to determine statistical significance. Results: The Posner criteria was satisfied in 45/75 patients (60%) using dynamic radiographs as compared to 32/75 patients (42.6%) when using spontaneous reduction seen on magnetic resonance imaging. This was statistically significant (p<0.01). However, we noted that 29/45 (64.4%) patients with instability diagnosed on dynamic radiographs also had it diagnosed on spontaneous reduction. Conclusion: Posner criteria when applied to spontaneous reduction seen on magnetic resonance imaging has a specificity of 90% and positive predictive value of 90.63%, assuming that satisfaction of Posner criteria on dynamic radiographs indicates true instability. The authors advocate the use of Posner criteria applied to spontaneous reduction to assess for spinal instability. Failure to satisfy the Posner criteria on spontaneous reduction should then prompt the use of a more sensitive modality such as dynamic radiographs.
目的:动态x线片被广泛用于评估放射性脊柱不稳定性。作者的目的是比较动态x线片和自发复位在磁共振成像上的敏感性,当与站立侧位x线片相比,在诊断不稳定性方面。材料和方法:本研究回顾性分析了来自单一中心的75例疑似临床腰椎不稳定的患者,这些患者表现为背部和/或腿部疼痛,并接受了腰骶棘磁共振成像和腰椎x线片系列检查。作者比较了动态x线片与磁共振成像的标准灵敏度(按照波斯纳标准)。采用Pearson卡方检验确定统计学显著性。结果:动态x线片符合波斯纳标准的患者为45/75(60%),而磁共振成像自发复位的患者为32/75(42.6%)。差异有统计学意义(p<0.01)。然而,我们注意到29/45(64.4%)在动态x线片上诊断为不稳定的患者也被诊断为自发复位。结论:Posner标准应用于磁共振成像上的自发复位特异性为90%,阳性预测值为90.63%,假设动态x线片上满足Posner标准表明确实不稳定。作者提倡使用Posner标准来评估脊柱不稳定。如果不能满足波斯纳自发复位标准,则应采用更灵敏的方式,如动态x线片。
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引用次数: 0
Post-Operative Adding-On in Adolescent Idiopathic Scoliosis, A Particular Etiology: Conflict Between the Upper Articular Process and the Instrumentation Material : A Case Report 青少年特发性脊柱侧凸的术后附加手术,一种特殊的病因:上关节突与内固定材料之间的冲突:1例报告
Pub Date : 2018-01-01 DOI: 10.4172/2165-7939.1000415
M. Siala, Daniel N’dele, F. Accadbled, J. S. Gauzy
The aim of surgical treatment of adolescent idiopathic scoliosis (AIS) is to achieve a balanced spine. Distal addingon is a postoperative phenomenon in AIS, which is characterized by a progressive correction loss. A 13-Year-old girl with AIS who underwent posterior arthrodesis showed aggravation of the disequilibrium under the last instrumented vertebra (LIV) 30 months post operatively and an increase of the lumbar curvature with no evident cause. Extension surgery was made and per operatively we noticed that the distal end of the arthrodesis was disengaged and that the left rod was conflicting with the upper left articular process of L2. Among the causes of adding-on we report in this article a particular etiology that consists in a conflict with the instrumentation material. This conflict has to be looked for postoperatively if an adding-on phenomenon is suspected in addition to a distally protruding rod, and could motivate a CT scan imaging for diagnosis.
手术治疗青少年特发性脊柱侧凸(AIS)的目的是实现脊柱平衡。远端附着是AIS术后的一种现象,其特征是进行性矫正丧失。一名13岁AIS女孩接受了后路关节融合术,术后30个月最后固定椎体(LIV)下的不平衡加剧,腰椎曲度增加,但没有明显原因。我们进行了伸展手术,术中我们注意到关节融合术的远端脱臼,左棒与L2的左上关节突相冲突。在附加的原因中,我们在本文中报告了与仪器材料冲突的特殊病因。如果怀疑除远端突出的杆状物外还有附加现象,则必须在术后寻找这种冲突,并可能促使CT扫描成像进行诊断。
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引用次数: 0
MicroRNA Based Therapy and Osteoporosis: A Review of a Novel Therapeutic Agent from Diagnosis to Treatment 基于MicroRNA的治疗与骨质疏松症:一种新型治疗剂从诊断到治疗的综述
Pub Date : 2018-01-01 DOI: 10.4172/2165-7939.1000416
F. Niknam, Nahid Davoodian, Dhuha Ali, Reza Vazifehmand, Tina Saber
Disequilibrium between bone resorption and bone formation may cause osteoporosis that reduces bone integrity and physiological function of skeletal system. Osteoblast and osteoclast genesis are two major of biological events that act in bone turnover and dynamic rate of bone remodeling. Ample evidences have been revealed that RANK-L/ OPG, Wnt and BMP Pathways are crucial pathways involved in osteoporosis. Treatment of osteoporosis is becoming important task in post menopause women and old people. Current treatment strategies with osteoporosis drugs are mainly by inhibiting the bone-resorbtion. However, these synthetic medicines have limitless side effects. Several studies have established the important of a group of small non-coding RNAs (MiRNAs) which involve in pathogenesis osteoporosis, bone remodeling, osteoblast differentiation and osteoclast formation and has consider as a gold biomarker for osteoporosis treatment. The pathogenicity factors of osteoporosis, pathways involved in the disease and potential replacement treatment have been emphasized in this paper.
骨吸收与骨形成之间的不平衡可能导致骨质疏松症,从而降低骨的完整性和骨骼系统的生理功能。成骨细胞和破骨细胞的发生是影响骨更新和骨重塑动态速率的两大生物事件。大量证据表明RANK-L/ OPG、Wnt和BMP通路是参与骨质疏松的重要通路。骨质疏松症的治疗已成为绝经后妇女和老年人的重要课题。目前骨质疏松药物的治疗策略主要是通过抑制骨吸收。然而,这些合成药物有无限的副作用。一些研究已经确定了一组小的非编码rna (MiRNAs)的重要性,它们参与骨质疏松症的发病、骨重塑、成骨细胞分化和破骨细胞的形成,并被认为是骨质疏松症治疗的黄金生物标志物。本文就骨质疏松症的致病因素、发病途径及可能的替代治疗作一综述。
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引用次数: 0
Epidemiology of Traumatic Spinal Injury: A 15-Year Retrospective Study of 1092 Cases 外伤性脊髓损伤的流行病学:1092例15年回顾性研究
Pub Date : 2018-01-01 DOI: 10.4172/2165-7939.1000429
S. Jc, Hope Jmv, D. Souleymane, Kassé An, Diouf Jd, Ni An, B. Thiam, M. Diallo, Camara Ehs, M. HabibSy
Background: Spinal trauma is a well‑documented problem in developed countries but literature has been mute on this problem in developing counties. The purpose of this study was to elucidate epidemiological characteristics of spine trauma in our center over a 15-year period. Methods: All consecutive patients with acute spinal trauma who were admitted in our center from March 2003 to March 2018 were included. The analysis was focused on patient-related demographic characteristics, cause and mechanism of injury, level and type of injury, neurological deficit, associated injuries, management and outcome. All of the statistical calculations were performed using the Statistical Package for Social Sciences (SPSS). Statistical analyses were conducted using the Student t-test and nonparametric tests (Mann-Whitney U-test, Kruskal-Wallis test). Values for p<0.05 were regarded as statistically significant and all confidence intervals were expressed at 95%. Results: A total of 1,092 patients with acute traumatic spinal injuries were managed in our trauma center. There were 74.3% males and 25.7% females with mean age 34.5 years. Young adults (age group: 18-39 years) were more affected with 58.9%. The leading mechanism of injury was compression with 39.2%. The most common cause of accident was motor vehicle collision accident (58.5%) followed by high-energy falls (32.6%). Six hundred eighty-seven patients (62.8%) had spinal cord injury, with 14.4% complete tetraplegia and 7.7% complete paraplegia. Overall, the use of operative treatment (64.8%) exceeded that of conservative treatment (35.2%). Conclusion: This study’s unique feature of delineating variables with statistical significance trending toward better management provides useful data to guide future researches, benchmarking, public health policy, and efficient resource allocation for the management of spine trauma.
背景:脊柱创伤在发达国家是一个有充分记录的问题,但文献对发展中国家的这一问题一直沉默。本研究的目的是阐明本中心15年来脊柱创伤的流行病学特征。方法:纳入2003年3月至2018年3月在我中心连续收治的急性脊柱创伤患者。分析的重点是患者相关的人口学特征、损伤的原因和机制、损伤的程度和类型、神经功能缺损、相关损伤、管理和结局。所有统计计算均使用社会科学统计软件包(SPSS)进行。采用学生t检验和非参数检验(Mann-Whitney u检验、Kruskal-Wallis检验)进行统计分析。p<0.05认为有统计学意义,所有置信区间均以95%表示。结果:我院创伤中心共收治急性外伤性脊髓损伤患者1092例。男性占74.3%,女性占25.7%,平均年龄34.5岁。青壮年(18-39岁)患病率更高,为58.9%。损伤机制以压迫为主,占39.2%。最常见的事故原因是机动车碰撞事故(58.5%),其次是高能坠落事故(32.6%)。脊髓损伤687例(62.8%),其中完全四肢瘫痪14.4%,完全截瘫7.7%。总体而言,手术治疗的使用率(64.8%)超过保守治疗(35.2%)。结论:本研究独特的特点是描述了具有统计学意义的变量,趋向于更好的管理,为指导未来的研究、标杆制定、公共卫生政策和有效的资源分配提供了有用的数据。
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引用次数: 1
Fully Endoscopic Lumbar Laminectomy for Treatment of Large Dorsal Ligamentum Flavum Cyst and Severe Spinal Stenosis: A Technical note on a Case Report 全内窥镜腰椎椎板切除术治疗大黄韧带背囊肿和严重椎管狭窄:一个病例报告的技术注释
Pub Date : 2018-01-01 DOI: 10.4172/2165-7939.s7-011
Jian Shen
Traditional open and tubular approaches for treatment of central and lateral recess spinal stenosis involve laminotomy or laminectomy with removal of overgrown ligamentum flavum and a portion of the medial facet joints in order to decompress the central canal and lateral recess. Fully-endoscopic posterior lumbar laminectomy follows similar principle but is a more minimally invasive approach with unique advantages. This case presentation describes a step-by-step technique for fully-endoscopic lumbar laminectomy and its unique advantages to achieve bilateral decompression with unilateral approach and en bloc excision of a large dorsal ligmentum flavum cyst.
传统的开放和管状入路治疗中央和外侧隐窝椎管狭窄包括椎板切开术或椎板切除术,切除过度生长的黄韧带和部分内侧小关节,以减压中央椎管和外侧隐窝。全内窥镜后腰椎椎板切除术遵循类似的原理,但具有独特的优势,是一种更微创的方法。本病例介绍了全内窥镜腰椎椎板切除术的一步一步技术及其独特的优势,通过单侧入路实现双侧减压,并整体切除大的背韧带黄囊肿。
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引用次数: 1
Advantages of Endoscope-Assisted Disc-FX in Surgical Management of Lumbar Disc Herniation: A Report of 10 Cases 内窥镜辅助Disc- fx在腰椎间盘突出症手术治疗中的优势(附10例报告
Pub Date : 2018-01-01 DOI: 10.4172/2165-7939.S7-015
Y. Hirano, K. Watanabe, S. Pawar, R. Bansil
Objective: Microsurgical discectomy is the gold standard treatment for the herniated nucleus pulposus (HNP) of the lumbar spine. On the other hand, less invasive procedures have been developed and accepted rapidly. Percutaneous endoscopic lumbar discectomy (PELD) was developed as one of the minimally invasive techniques for HNP of the lumbar spine, and satisfactory outcomes have been reported. For the contained type HNP or discogenic pain, however, surgical indication of PELD is sometimes controversial. We describe our experiences of surgical treatment with DiscFX, focusing on advantages of endoscopic observation. Patients and Methods: A total of 10 patients with contained type HNP were treated with Disc-FX system. DiscFX was carried out percutaneously under local anesthesia using a cannula of 3.4 mm diameter, with a trajectory compatible with the transforaminal approach of the PELD. Endoscope was introduced intermittently in 5 patients to observe the results of each procedure. Results: Sufficient pain relief was achieved in all patients, and Japanese Orthopedic Association score improved from 7-16 (mean 13.0) to 22-29 (mean 25.9), and visual analogue scale improved from 6-10 (mean 8.0) to 0-3 (mean 1.2). Endoscopic observation enabled the procedure almost equivalent to targeted fragmentectomy, and contributed in better surgical outcome. Conclusion: Disc-FX is a promising procedure in the armamentarium of minimally invasive surgery for the selected conditions of patients, and endoscopic observation is considered to be beneficial in more accurate and adequate decompression. Citation: Hirano Y, Pawar S, Bansil R, Watanabe K (2018) Advantages of Endoscope-Assisted Disc-FX in Surgical Management of Lumbar Disc Herniation: A Report of 10 Cases. J Spine 7: 015. doi: 10.0142/2165-7939.1000015
目的:显微外科椎间盘切除术是治疗腰椎髓核突出症的金标准。另一方面,侵入性较小的手术已经发展并被迅速接受。经皮内镜下腰椎间盘切除术(PELD)是治疗腰椎HNP的微创技术之一,已有令人满意的结果报道。然而,对于包含型HNP或椎间盘源性疼痛,PELD的手术指征有时存在争议。我们描述了使用DiscFX进行手术治疗的经验,重点介绍了内镜下观察的优势。患者与方法:采用Disc-FX系统对10例含型HNP患者进行治疗。DiscFX在局麻下经皮穿刺,使用直径3.4 mm的套管,其轨迹与经椎间孔入路一致。5例患者间歇引入内窥镜,观察每次手术的效果。结果:所有患者均获得充分的疼痛缓解,日本骨科协会评分从7-16分(平均13.0分)提高到22-29分(平均25.9分),视觉模拟评分从6-10分(平均8.0分)提高到0-3分(平均1.2分)。内窥镜观察使手术几乎等同于靶向碎片切除术,并有助于更好的手术效果。结论:对于特定条件的患者,Disc-FX是一种很有前景的微创手术方法,内镜下观察有助于更准确、充分的减压。引用本文:Hirano Y, Pawar S, Bansil R, Watanabe K(2018)内窥镜辅助Disc- fx在腰椎间盘突出症手术治疗中的优势:10例报告。[J]中华医学杂志7:015。doi: 10.0142 / 2165 - 7939.1000015
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引用次数: 1
The Effect of Spinal Arte Care (™) Manipulation Techniques in a Case of Adult Idiopathic Scoliosis 脊柱关节护理(™)手法在成人特发性脊柱侧凸一例中的效果
Pub Date : 2018-01-01 DOI: 10.4172/2165-7939.s7-016
V. Yadav, Ravinder Yadav, James Wong
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引用次数: 0
The Yeung Percutaneous Endoscopic Lumbar Decompressive Technique (YESS TM ) Yeung经皮内镜腰椎减压术(YESS TM)
Pub Date : 2018-01-01 DOI: 10.4172/2165-7939.1000408
A. Yeung
Endoscopic spine surgery is receiving intense interest as minimally invasive techniques, robotics and biologics are the latest focus in spine care that is embraced by a myriad of providers, all touting their area of expertise as the answer to treating painful conditions of the spine. All stakeholders agree that if non-surgical methods of treatment are effective, the natural adaptation of painful degenerative conditions will eventually be mitigated or resolved with some modification of work or activities of daily living that avoids aggravating the clinical condition or delays a rapid advancement to a painful condition. Each stakeholder in the treatment spectrum is touting, and marketing their areas of expertise, but few stakeholders work together in a truly multidisciplinary and cooperative agenda. Procedural or surgical interventions are easiest to market and to measure its efficacy and cost effectiveness. The cumulative cost of spinal care is, however, becoming less affordable as spinal care does not follow the economics of a free market since increased consumption and availability does not result in decreased cost as an economic model. There is a need for cooperation and a focus on the diagnosis and treatment of common painful conditions of an aging spine, starting with common back pain that affects tens of millions of patients. Back pain is one of the most costly and debilitating conditions universally affecting work productivity. In the United States and in industrialized countries, new procedures for back pain tend to “follow the money” aided by industry. In Asian and OUS countries, there is more acceptance of traditional non-surgical treatment from thousands of years of medical treatment history. New and non-traditional treatments based on evolving science, are being made readily available in the information highway by Open Access Journals where researchers can publish their Level V evidenced based concepts for interested parties and other scientists. Anthony T. Yeung’s work focuses on the surgical treatment of the pain generator in the lumbar spine. Patient selection is aided by using diagnostic and therapeutic injections, to identify the likelihood of surgical success when the pain source is targeted. This article focuses on the details of Yeung’s 27 years’ experience on identifying and treating the pain generators in the lumbar spine by an endoscope and combined with an endoscopic system that he has trademarked the Yeung Endoscopic Spine System (YESSTM).
内窥镜脊柱手术正受到人们的强烈兴趣,因为微创技术、机器人技术和生物制剂是脊柱护理的最新焦点,受到无数供应商的欢迎,他们都在兜售自己的专业领域,作为治疗脊柱疼痛状况的答案。所有利益相关者都同意,如果非手术治疗方法有效,疼痛的退行性疾病的自然适应最终将得到缓解或解决,通过对日常生活的工作或活动进行一些修改,避免加重临床病情或延缓迅速发展到疼痛状态。治疗领域的每个利益相关者都在吹捧和推销自己的专业领域,但很少有利益相关者在真正的多学科合作议程中共同努力。程序或外科干预是最容易市场化和衡量其疗效和成本效益。然而,脊柱护理的累积成本变得越来越难以负担,因为脊柱护理不遵循自由市场的经济学,因为作为一种经济模式,增加的消费和可用性并不会导致成本下降。有必要进行合作,并把重点放在诊断和治疗脊柱老化的常见疼痛上,从影响数千万患者的常见背痛开始。背痛是影响工作效率的最昂贵和最虚弱的疾病之一。在美国和工业化国家,治疗背痛的新方法往往是在工业的帮助下“跟着钱走”。在亚洲和美国,从几千年的医疗历史来看,传统的非手术治疗方式越来越被接受。基于不断发展的科学的新的和非传统的治疗方法,正在通过开放获取期刊在信息高速公路上随时可用,研究人员可以向感兴趣的各方和其他科学家发表他们的基于第五级证据的概念。Anthony T. Yeung的工作重点是腰椎疼痛源的手术治疗。通过使用诊断性和治疗性注射来辅助患者选择,以确定手术成功的可能性。本文重点介绍了杨氏27年来通过内窥镜识别和治疗腰椎疼痛源的经验,并结合了他已注册为Yeung内窥镜脊柱系统(YESSTM)的内窥镜系统。
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引用次数: 11
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Journal of spine
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