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BJOG: An International Journal of Obstetrics & Gynaecology最新文献

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The Impact of Dating Twin Pregnancy by the Larger, Smaller or Mean Twin Crown-Rump Length: A Retrospective Cohort Study 大、小或平均双胞胎冠臀长度对双胞胎怀孕的影响:一项回顾性队列研究
Pub Date : 2025-01-09 DOI: 10.1111/1471-0528.18065
Gillian V. Blayney, Veronica Giorgione, Amar Bhide, Basky Thilaganathan
To evaluate the impact of twin dating by ultrasound-measured crown-rump length (CRL) of the larger (CRL-L), smaller (CRL-S) or mean twin measurement (CRL-M) on the rates of preterm birth (PTB) and detection of small for gestational age (SGA) births.
目的:评价超声测量较大(CRL- l)、较小(CRL- s)或平均双胞胎测量(CRL- m)的冠臀长度(CRL)对早产(PTB)率和小胎龄(SGA)出生检出率的影响。
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引用次数: 0
Optimising Luteinising Hormone Levels on Trigger Day for Improved Ovarian Response and Pregnancy Outcomes in Gonadotropin-Releasing Hormone Antagonist Protocols: A Retrospective Cohort Study 在促性腺激素释放激素拮抗剂方案中,优化触发日促黄体生成素水平以改善卵巢反应和妊娠结局:一项回顾性队列研究
Pub Date : 2025-01-08 DOI: 10.1111/1471-0528.18064
Zijin Xu, Qiwang Lin, Zhu Liang, Sichen Li, Yixuan Wu, Yang Fu, Jianqiao Liu, Haiying Liu
To determine the optimal luteinising hormone (LH) level on the trigger day and its impact on pregnancy outcomes in gonadotropin-releasing hormone (GnRH) antagonist protocols using a data-driven approach.
使用数据驱动的方法确定促性腺激素释放激素(GnRH)拮抗剂方案中触发日的最佳促黄体生成素(LH)水平及其对妊娠结局的影响。
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引用次数: 0
Comprehensive Health Assessment of School-Age Children Conceived by Assisted Reproductive Technology: A Prospective Cohort Follow-Up Study 辅助生殖技术受孕学龄儿童的综合健康评估:一项前瞻性队列随访研究
Pub Date : 2025-01-08 DOI: 10.1111/1471-0528.18044
Jing Wang, Lingling Chen, Yonghong Yong, Xiang Yu, Yin Chen, Jie Zhang, Xinru Xia, Yugui Cui, Feiyang Diao, Jiayin Liu, Yan Meng
To assess the comprehensive health status of school-age children conceived through assisted reproductive technology (ART) compared to that of those conceived naturally.
评估通过辅助生殖技术(ART)受孕的学龄儿童与自然受孕的学龄儿童的综合健康状况。
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引用次数: 0
Addressing Limitations in Stillbirth Assessment Research: A Call for Broader Perspectives 解决死产评估研究的局限性:呼吁更广阔的视角
Pub Date : 2025-01-08 DOI: 10.1111/1471-0528.18061
Sijia Liu, Jialao Ma
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{"title":"Addressing Limitations in Stillbirth Assessment Research: A Call for Broader Perspectives","authors":"Sijia Liu, Jialao Ma","doi":"10.1111/1471-0528.18061","DOIUrl":"https://doi.org/10.1111/1471-0528.18061","url":null,"abstract":"Click on the article title to read more.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"65 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142936490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Urgent Need to Address Perinatal Mental Health After Stillbirth in Low- and Middle-Income Countries 迫切需要解决低收入和中等收入国家死产后围产期心理健康问题
Pub Date : 2025-01-07 DOI: 10.1111/1471-0528.18060
Hsia-Chun Lai, Lien-Chung Wei
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引用次数: 0
BJOG-24-1072.R2 Postpartum Pre-Eclampsia: Novel Insights Into a Complex Clinical Entity 问卷- 24 - 1072。R2产后先兆子痫:对复杂临床实体的新见解
Pub Date : 2025-01-07 DOI: 10.1111/1471-0528.18056
Frances Conti-Ramsden, Antonio de Marvao, Lucy Chappell

Conflicts of Interest

The authors declare no conflicts of interest.

利益冲突作者声明无利益冲突。
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引用次数: 0
Representativeness of Study Population: A Critical Consideration for Applying Gestational Age Estimation Models 研究人群的代表性:应用胎龄估计模型的关键考虑因素
Pub Date : 2025-01-06 DOI: 10.1111/1471-0528.18059
Zhenjiao Liang, Xiu Qin, Dongna Wang
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引用次数: 0
Finding the Balance: Can We Optimise Episiotomy Practices to Reduce OASIS? 寻找平衡:我们能否优化会阴切开术以减少OASIS?
Pub Date : 2025-01-06 DOI: 10.1111/1471-0528.18057
Binglin Li, Yueqi Feng, Ruijuan Chen
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{"title":"Finding the Balance: Can We Optimise Episiotomy Practices to Reduce OASIS?","authors":"Binglin Li, Yueqi Feng, Ruijuan Chen","doi":"10.1111/1471-0528.18057","DOIUrl":"https://doi.org/10.1111/1471-0528.18057","url":null,"abstract":"Click on the article title to read more.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"83 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142929529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of Social Work in Promoting Healthy Prepregnancy Lifestyles to Reduce Adverse Pregnancy Outcomes 社会工作在促进健康的孕前生活方式以减少不良妊娠结局中的作用
Pub Date : 2025-01-06 DOI: 10.1111/1471-0528.18058
Binzhu Zhao, Zeping Chen, Xiaoling Bu, Lincheng Duan
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{"title":"The Role of Social Work in Promoting Healthy Prepregnancy Lifestyles to Reduce Adverse Pregnancy Outcomes","authors":"Binzhu Zhao, Zeping Chen, Xiaoling Bu, Lincheng Duan","doi":"10.1111/1471-0528.18058","DOIUrl":"https://doi.org/10.1111/1471-0528.18058","url":null,"abstract":"Click on the article title to read more.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142929462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Smoking, Genetic Susceptibility and Early Menopause: Unveiling Biological Mechanisms and Potential Therapy Targets 吸烟、遗传易感性和早期绝经:揭示生物学机制和潜在治疗靶点
Pub Date : 2024-12-27 DOI: 10.1111/1471-0528.18052
Yuhang Liang, Jie Ou, Jing Fu, Yijing Wang, Yanping Li, Jinchen Li, Yan Yi
ObjectiveTo explore the association between smoking, genetic susceptibility and early menopause (EM) and clarify the potential mechanisms underlying this relationship.DesignAn observational and Transcriptome‐wide association analysis (TWAS) study.SettingUK Biobank and public summary statistics.Population139 869 women with full baseline and menopause data, and no gynaecological surgery history.MethodsAdjusted modified Poisson regression models were developed to determine the smoking and genetic risk effects on EM. TWAS was used to identify gene expression between smoking and EM, with Mendelian randomisation (MR) to infer causality. Enrichment analysis explored regulatory networks of transcription factors, microRNAs and potential therapeutic targets. Small molecule drugs were predicted using drug‐gene interaction analysis.Main Outcome MeasuresEM prevalence and common gene expression patterns.ResultsWomen with over 30 pack‐years of smoking had about 1.5 times higher EM risk, with RRs of 1.39 (95%CI, 1.23–1.56), 1.45 (1.33–1.59) and 1.45 (1.36–1.55) in the low, intermediate and high genetic risk groups. TWAS identified hub genes such as IMMP2L, BMPR2 and HMGN1. MR confirmed daily cigarette consumption as a causal factor in early menopause. Several potential therapeutic targets (e.g., SP600125, INCB18424 and ruxolitinib) were identified.ConclusionsSmoking reduction significantly lowered the risk of EM. Hub genes and therapeutic targets identified provided new avenues for mitigating harmful effects of smoking.
目的探讨吸烟、遗传易感性与早期绝经(EM)之间的关系,并阐明这种关系的潜在机制。设计一项观察性和全转录组关联分析(TWAS)研究。设置英国生物银行和公共汇总统计。人群139,869名具有完整的基线和更年期资料,无妇科手术史的妇女。方法建立调整后的修正泊松回归模型,以确定吸烟和遗传风险对EM的影响。TWAS用于确定吸烟和EM之间的基因表达,孟德尔随机化(MR)推断因果关系。富集分析探讨了转录因子、microrna和潜在治疗靶点的调控网络。使用药物-基因相互作用分析预测小分子药物。主要观察指标:sem患病率和常见基因表达模式。结果吸烟超过30包年的女性发生EM的风险高出1.5倍,低、中、高遗传风险组的rr分别为1.39 (95%CI, 1.23-1.56)、1.45(1.33-1.59)和1.45(1.36-1.55)。TWAS鉴定出IMMP2L、BMPR2和HMGN1等枢纽基因。MR证实每日吸烟是导致更年期提前的原因。确定了几个潜在的治疗靶点(如SP600125、INCB18424和ruxolitinib)。结论减少吸烟可显著降低EM风险,Hub基因和治疗靶点的发现为减轻吸烟的有害影响提供了新的途径。
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引用次数: 0
期刊
BJOG: An International Journal of Obstetrics & Gynaecology
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