Pailin Pongratanakul, Marieke Vermeulen‐Spohn, Carolin Wöltjen, Sophia Thy, Andreas Hiester, Peter Albers, Yue Che
ObjectiveTo analyse a comparatively large cohort of patients who underwent robot‐assisted retroperitoneal lymph node dissection (R‐RPLND) in a single centre, assessing the peri‐operative and oncological safety of this procedure compared to that in a matched‐pair cohort of patients who underwent open retroperitoneal lymph node dissection (O‐RPLND).MethodsWe retrospectively identified 100 patients who underwent R‐RPLND between October 2010 and January 2024. A matched‐pair analysis of R‐RPLNDs and O‐RPLNDs was conducted based on the following criteria: surgical indication, histology, clinical stage (CS), and tumour size. The primary endpoint of this analysis was progression‐free survival (PFS). Secondary endpoints were peri‐operative parameters.ResultsBased on surgical indication, the R‐RPLND cohort was divided into four groups: CS II seminoma (Group 1, 42 patients); marker‐negative CS II non‐seminoma (Group 2, 15 patients); CS I non‐seminoma with high‐risk factors (Group 3, seven patients), and post‐chemotherapy patients (Group 4, 34 patients). Two patients were excluded due to uncommon testicular histology. With a mean follow‐up of 32, 31, 32 and 28 months in the four groups, respectively, relapses occurred in 10/42 of Group 1, 3/15 of Group 2, and 1/7 of Group 3, while all patients remained relapse‐free in Group 4. The matched‐pair analysis revealed that histological retroperitoneal lymph node dissection specimens, relapse rates, and PFS were similar in the R‐RPLND and O‐RPLND groups. R‐RPLND had advantages in terms of a shorter hospital stay as a surrogate for less morbidity.ConclusionIn selected patients and selected surgical indications, R‐RPLND represents a minimally invasive alternative to O‐RPLND in the management of patients with testicular germ cell tumours.
{"title":"Matched‐pair analysis of peri‐operative and oncological outcomes of robot‐assisted vs open retroperitoneal lymph node dissection","authors":"Pailin Pongratanakul, Marieke Vermeulen‐Spohn, Carolin Wöltjen, Sophia Thy, Andreas Hiester, Peter Albers, Yue Che","doi":"10.1111/bju.16747","DOIUrl":"https://doi.org/10.1111/bju.16747","url":null,"abstract":"ObjectiveTo analyse a comparatively large cohort of patients who underwent robot‐assisted retroperitoneal lymph node dissection (R‐RPLND) in a single centre, assessing the peri‐operative and oncological safety of this procedure compared to that in a matched‐pair cohort of patients who underwent open retroperitoneal lymph node dissection (O‐RPLND).MethodsWe retrospectively identified 100 patients who underwent R‐RPLND between October 2010 and January 2024. A matched‐pair analysis of R‐RPLNDs and O‐RPLNDs was conducted based on the following criteria: surgical indication, histology, clinical stage (CS), and tumour size. The primary endpoint of this analysis was progression‐free survival (PFS). Secondary endpoints were peri‐operative parameters.ResultsBased on surgical indication, the R‐RPLND cohort was divided into four groups: CS II seminoma (Group 1, 42 patients); marker‐negative CS II non‐seminoma (Group 2, 15 patients); CS I non‐seminoma with high‐risk factors (Group 3, seven patients), and post‐chemotherapy patients (Group 4, 34 patients). Two patients were excluded due to uncommon testicular histology. With a mean follow‐up of 32, 31, 32 and 28 months in the four groups, respectively, relapses occurred in 10/42 of Group 1, 3/15 of Group 2, and 1/7 of Group 3, while all patients remained relapse‐free in Group 4. The matched‐pair analysis revealed that histological retroperitoneal lymph node dissection specimens, relapse rates, and PFS were similar in the R‐RPLND and O‐RPLND groups. R‐RPLND had advantages in terms of a shorter hospital stay as a surrogate for less morbidity.ConclusionIn selected patients and selected surgical indications, R‐RPLND represents a minimally invasive alternative to O‐RPLND in the management of patients with testicular germ cell tumours.","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"46 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143857481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gabriele Bignante, David O. Katz, William A. Langbo, Angelo Orsini, Francesco Lasorsa, Edward E. Cherullo, Riccardo Autorino, Srinivas Vourganti
{"title":"Robot‐assisted MRI/US fusion transperineal prostate biopsy using the Biobot system: a single‐centre experience","authors":"Gabriele Bignante, David O. Katz, William A. Langbo, Angelo Orsini, Francesco Lasorsa, Edward E. Cherullo, Riccardo Autorino, Srinivas Vourganti","doi":"10.1111/bju.16742","DOIUrl":"https://doi.org/10.1111/bju.16742","url":null,"abstract":"","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"49 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143853532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Igor Duquesne, Pierre-Etienne Gabriel, Mohamad Abou Chakra, Mohamad Moussa, Raymond Mansour, Mihnea Bogdan Borz, Louise Duffaut, Benoit Mesnard, Said Ourfali, Jeremy Mercier, Michaël Peyromaure, Alexandre de la Taille, Jérôme Rigaud, Alain Ruffion, Frédéric Panthier, Evanguelos Xylinas, Alexandra Masson-Lecomte, Morgan Rouprêt, Thomas Seisen, Mathieu Roumiguié
To externally validate the tetrafecta and pentafecta frameworks for assessing the quality of radical nephroureterectomy (RNU) and their correlation with oncological outcomes in patients with localised upper tract urothelial carcinoma (UTUC).
{"title":"External validation of current quality care metrics after radical nephroureterectomy","authors":"Igor Duquesne, Pierre-Etienne Gabriel, Mohamad Abou Chakra, Mohamad Moussa, Raymond Mansour, Mihnea Bogdan Borz, Louise Duffaut, Benoit Mesnard, Said Ourfali, Jeremy Mercier, Michaël Peyromaure, Alexandre de la Taille, Jérôme Rigaud, Alain Ruffion, Frédéric Panthier, Evanguelos Xylinas, Alexandra Masson-Lecomte, Morgan Rouprêt, Thomas Seisen, Mathieu Roumiguié","doi":"10.1111/bju.16741","DOIUrl":"https://doi.org/10.1111/bju.16741","url":null,"abstract":"To externally validate the tetrafecta and pentafecta frameworks for assessing the quality of radical nephroureterectomy (RNU) and their correlation with oncological outcomes in patients with localised upper tract urothelial carcinoma (UTUC).","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"34 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143853638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Helen Bell-Gorrod, Praveen Thokala, Suzanne Breeman, David Cooper, Graeme MacLennan, Mohamed Abdel-Fattah, Simon Dixon
To estimate the cost-effectiveness of using invasive urodynamic studies (UDS) in the management of women with refractory overactive bladder (OAB) symptoms using the results of the FUTURE trial.
{"title":"Long-term cost-effectiveness of invasive urodynamic studies for overactive bladder in women","authors":"Helen Bell-Gorrod, Praveen Thokala, Suzanne Breeman, David Cooper, Graeme MacLennan, Mohamed Abdel-Fattah, Simon Dixon","doi":"10.1111/bju.16703","DOIUrl":"https://doi.org/10.1111/bju.16703","url":null,"abstract":"To estimate the cost-effectiveness of using invasive urodynamic studies (UDS) in the management of women with refractory overactive bladder (OAB) symptoms using the results of the FUTURE trial.","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"23 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143849370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nikolaos Pyrgidis, Michael Chaloupka, Benedikt Ebner, Yannic Volz, Philipp Weinhold, Julian Marcon, Lennert Eismann, Christian G. Stief, Gerald B. Schulz, Maria Apfelbeck
To compare the perioperative complications of the most common focal therapy (FT) modalities for prostate cancer.
比较最常见的前列腺癌病灶治疗（FT）模式的围手术期并发症。
{"title":"Perioperative complications of focal therapy for prostate cancer: results from the GeRmAn Nationwide inpatient Data (GRAND) study","authors":"Nikolaos Pyrgidis, Michael Chaloupka, Benedikt Ebner, Yannic Volz, Philipp Weinhold, Julian Marcon, Lennert Eismann, Christian G. Stief, Gerald B. Schulz, Maria Apfelbeck","doi":"10.1111/bju.16746","DOIUrl":"https://doi.org/10.1111/bju.16746","url":null,"abstract":"To compare the perioperative complications of the most common focal therapy (FT) modalities for prostate cancer.","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"44 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143849371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Siberyn T. Nuijens, Lisa M.C. van Hoogstraten, Noëlle B. Terpstra, Ivy Beeren, Alina Vrieling, Eveline M. Wijnen, Richard P. Meijer, Lambertus A. Kiemeney, J. Alfred Witjes, Katja K.H. Aben
To evaluate the impact of treatment for localised muscle-invasive bladder cancer (MIBC) during the first 2 years after diagnosis.
{"title":"The impact of treatment for muscle-invasive bladder cancer on health-related quality of life","authors":"Siberyn T. Nuijens, Lisa M.C. van Hoogstraten, Noëlle B. Terpstra, Ivy Beeren, Alina Vrieling, Eveline M. Wijnen, Richard P. Meijer, Lambertus A. Kiemeney, J. Alfred Witjes, Katja K.H. Aben","doi":"10.1111/bju.16736","DOIUrl":"https://doi.org/10.1111/bju.16736","url":null,"abstract":"To evaluate the impact of treatment for localised muscle-invasive bladder cancer (MIBC) during the first 2 years after diagnosis.","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"3 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143841294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to “Recent advancements in the Ward AdmSsion of Haematuria: an observational mUlticentre sTudy (WASHOUT)—a large‐scale observational multicentre study of inpatient haematuria”","authors":"","doi":"10.1111/bju.16745","DOIUrl":"https://doi.org/10.1111/bju.16745","url":null,"abstract":"","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"1 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143836700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stacy Loeb, Mariana Rangel Camacho, Tatiana Sanchez Nolasco, Nataliya Byrne, Adrian Rivera, LaMont Barlow, June Chan, Scarlett Gomez, Aisha T. Langford
Disclosure of Interests
Stacy Loeb reports a research grant from Endo, and consulting with Astellas, Blue Earth, Endo, Doceree, and Savour Health, unrelated to the present manuscript. The remaining authors have no disclosures.
{"title":"Combating online misinformation in clinical encounters","authors":"Stacy Loeb, Mariana Rangel Camacho, Tatiana Sanchez Nolasco, Nataliya Byrne, Adrian Rivera, LaMont Barlow, June Chan, Scarlett Gomez, Aisha T. Langford","doi":"10.1111/bju.16734","DOIUrl":"https://doi.org/10.1111/bju.16734","url":null,"abstract":"<h2> Disclosure of Interests</h2>\u0000<p>Stacy Loeb reports a research grant from Endo, and consulting with Astellas, Blue Earth, Endo, Doceree, and Savour Health, unrelated to the present manuscript. The remaining authors have no disclosures.</p>","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"7 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143837065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
<p>A non-transpapillary technique [<span>1</span>] seems to facilitate access to the kidney, the most crucial aspect of percutaneous nephrolithotomy, compared to the classic transpapillary method [<span>2</span>].</p><p>In modern times, the godfathers of percutaneous access, Goodwin et al. [<span>3</span>], who illustrated a pyelostomy rather than a nephrostomy in Fig. 2 of their 1955 article, should be commended for their non-papillary puncture.</p><p>From the contemporary first accounts of ‘experience with a central, noncalyceal puncture protocol for percutaneous nephrolithotripsy’ [<span>4</span>] in 2017, a myth has persisted that has carried through to all subsequent studies on the subject, including the study by Lotfi et al. [<span>1</span>], that the ‘Current understanding of anatomical background of percutaneous access is based mostly on the very extensive documentation by Sampaio’ [<span>4</span>].</p><p>By the time of Sampaio's publications, 15 years after the introduction of endoscopic PNL in the late 1970s, several thousand PNLs had probably been performed worldwide based on the transpapillary principle. The first instruments specifically designed in 1980 for endoscopically controlled PNL [<span>2</span>] followed two principles: Access through the least vascularised part of the parenchyma and access with the nephrosocpe into the collecting system at the point where it is connected to the parenchyma, i.e. the collecting system itself should not be injured. The aim was to avoid vascular trauma and extravasation and also to reach even the most peripherally located calyceal stone.</p><p>This was the reversal of the least traumatic way to place a nephrostomy tube into the collecting system from the point of view of a urologist influenced by having previously performed open surgery. In the times of open surgery, a forceps was pushed transpapillary from the calyx, an anatomically preformed tract, to the surface of the kidney in order to pull the nephrostomy tube into the collecting system. In the late 1960s, John Wickham [<span>5</span>] added the open transpapillary avascular multiple radial nephrotomies technique for the removal of staghorn calculi to this decades-old transpapillary technique. This was later refined by a team at the University of Mainz, who performed staghorn surgery without clamping the renal artery, utilising only transpapillary access.</p><p>In PNL, I have not always hit the mark with a perfect transpapillary approach when carrying out PNL, but was sometimes happy simply to obtain access (Fig. 1). In one of his many articles on open stone surgery, Wickham described ‘Large venous anastomoses … like collars around the calyceal necks.’ In my experience and that of others (Tursunkulov AN, Akfamedline University Hospital, Central Asian University, Tashkent; personal communication), this description fits the annoying venous oozing frequently observed behind the nephroscope when using the non-papillary access method, whi
{"title":"Percutaneous nephrolithotomy: wisdom, dogma, paradigm and myths surrounding puncture","authors":"Peter Alken","doi":"10.1111/bju.16740","DOIUrl":"https://doi.org/10.1111/bju.16740","url":null,"abstract":"<p>A non-transpapillary technique [<span>1</span>] seems to facilitate access to the kidney, the most crucial aspect of percutaneous nephrolithotomy, compared to the classic transpapillary method [<span>2</span>].</p>\u0000<p>In modern times, the godfathers of percutaneous access, Goodwin et al. [<span>3</span>], who illustrated a pyelostomy rather than a nephrostomy in Fig. 2 of their 1955 article, should be commended for their non-papillary puncture.</p>\u0000<p>From the contemporary first accounts of ‘experience with a central, noncalyceal puncture protocol for percutaneous nephrolithotripsy’ [<span>4</span>] in 2017, a myth has persisted that has carried through to all subsequent studies on the subject, including the study by Lotfi et al. [<span>1</span>], that the ‘Current understanding of anatomical background of percutaneous access is based mostly on the very extensive documentation by Sampaio’ [<span>4</span>].</p>\u0000<p>By the time of Sampaio's publications, 15 years after the introduction of endoscopic PNL in the late 1970s, several thousand PNLs had probably been performed worldwide based on the transpapillary principle. The first instruments specifically designed in 1980 for endoscopically controlled PNL [<span>2</span>] followed two principles: Access through the least vascularised part of the parenchyma and access with the nephrosocpe into the collecting system at the point where it is connected to the parenchyma, i.e. the collecting system itself should not be injured. The aim was to avoid vascular trauma and extravasation and also to reach even the most peripherally located calyceal stone.</p>\u0000<p>This was the reversal of the least traumatic way to place a nephrostomy tube into the collecting system from the point of view of a urologist influenced by having previously performed open surgery. In the times of open surgery, a forceps was pushed transpapillary from the calyx, an anatomically preformed tract, to the surface of the kidney in order to pull the nephrostomy tube into the collecting system. In the late 1960s, John Wickham [<span>5</span>] added the open transpapillary avascular multiple radial nephrotomies technique for the removal of staghorn calculi to this decades-old transpapillary technique. This was later refined by a team at the University of Mainz, who performed staghorn surgery without clamping the renal artery, utilising only transpapillary access.</p>\u0000<p>In PNL, I have not always hit the mark with a perfect transpapillary approach when carrying out PNL, but was sometimes happy simply to obtain access (Fig. 1). In one of his many articles on open stone surgery, Wickham described ‘Large venous anastomoses … like collars around the calyceal necks.’ In my experience and that of others (Tursunkulov AN, Akfamedline University Hospital, Central Asian University, Tashkent; personal communication), this description fits the annoying venous oozing frequently observed behind the nephroscope when using the non-papillary access method, whi","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"136 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143832018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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