Tom Lister, Stan Batchelor, Mike Regan, Jason Britton, Hari Ratan, Feras Al-Jaafari, Jake Patterson, British Medical Laser Association and the British Association of Urological Surgeons Endourology Section
Objectives
This work examines the current evidence available regarding the risks of eye injury in endourology laser environments with the aim of providing a consensus recommendation on the appropriate use of protective eyewear.
Methods
A working group was set up consisting of urological surgeons and laser protection advisors. A literature review was conducted to identify articles relevant to endourology practice and the commonly used lasers, and these were reviewed by the working group. Searches of the medical device fault/reporting databases were also undertaken. A consensus was developed and shared with stakeholders.
Results
No reports of eye injuries from Ho:YAG, Tm:YAG, or Thulium Fibre Lasers (TFLs) were identified, although reports of skin burns and equipment-related fires were found. Available evidence suggests that ocular risks in endourology from these lasers are minimal and limited to rare cases of reversible corneal damage. Protective eyewear can further reduce this risk. However, Lasers with wavelengths below 1400 nm pose significant ocular risks, including blindness.
Conclusion
Personnel working in an endourology environment using Ho:YAG, Tm:YAG, or TFLs face minimal ocular risks when adhering to established safety procedures, and laser-specific eyewear may not always be essential. This requires an understanding of the hazards and risks and is in accordance with the recommendations herein, which should form the basis for relevant local rules. Protective eyewear remains critical when using visible and near-infrared lasers due to the heightened associated ocular risks.
{"title":"Recommendation on the use of protective eyewear in endourological laser procedures","authors":"Tom Lister, Stan Batchelor, Mike Regan, Jason Britton, Hari Ratan, Feras Al-Jaafari, Jake Patterson, British Medical Laser Association and the British Association of Urological Surgeons Endourology Section","doi":"10.1111/bju.16664","DOIUrl":"10.1111/bju.16664","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This work examines the current evidence available regarding the risks of eye injury in endourology laser environments with the aim of providing a consensus recommendation on the appropriate use of protective eyewear.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A working group was set up consisting of urological surgeons and laser protection advisors. A literature review was conducted to identify articles relevant to endourology practice and the commonly used lasers, and these were reviewed by the working group. Searches of the medical device fault/reporting databases were also undertaken. A consensus was developed and shared with stakeholders.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>No reports of eye injuries from Ho:YAG, Tm:YAG, or Thulium Fibre Lasers (TFLs) were identified, although reports of skin burns and equipment-related fires were found. Available evidence suggests that ocular risks in endourology from these lasers are minimal and limited to rare cases of reversible corneal damage. Protective eyewear can further reduce this risk. However, Lasers with wavelengths below 1400 nm pose significant ocular risks, including blindness.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Personnel working in an endourology environment using Ho:YAG, Tm:YAG, or TFLs face minimal ocular risks when adhering to established safety procedures, and laser-specific eyewear may not always be essential. This requires an understanding of the hazards and risks and is in accordance with the recommendations herein, which should form the basis for relevant local rules. Protective eyewear remains critical when using visible and near-infrared lasers due to the heightened associated ocular risks.</p>\u0000 </section>\u0000 </div>","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"135 4","pages":"577-581"},"PeriodicalIF":3.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/bju.16664","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143072578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bing Jie Chow, Alexander Light, Arjun Nathan, Loic Baekelandt, Gautier Marcq, Stefanie Croghan, Fortis Gaba, Francesco Esperto, Luca Orecchia, Carlos Toribio-Vázquez, Juan Gómez Rivas, Adrian Chi-Heng Fung, Kaleab Habtemichael Gebreselassie, Eduardo Felicio, Aria Danurdoro, Nikolaos Pyrgidis, Vukovic Marko, Jan Svihra, Mohamed Javid, Andrés Salas, Tran Trung Thanh, Cameron Alexander, Nikita Bhatt, Sinan Khadhouri, Veeru Kasivisvanathan, Kevin Byrnes
{"title":"Global comparison of research ethical review protocols: insights from an international research collaborative.","authors":"Bing Jie Chow, Alexander Light, Arjun Nathan, Loic Baekelandt, Gautier Marcq, Stefanie Croghan, Fortis Gaba, Francesco Esperto, Luca Orecchia, Carlos Toribio-Vázquez, Juan Gómez Rivas, Adrian Chi-Heng Fung, Kaleab Habtemichael Gebreselassie, Eduardo Felicio, Aria Danurdoro, Nikolaos Pyrgidis, Vukovic Marko, Jan Svihra, Mohamed Javid, Andrés Salas, Tran Trung Thanh, Cameron Alexander, Nikita Bhatt, Sinan Khadhouri, Veeru Kasivisvanathan, Kevin Byrnes","doi":"10.1111/bju.16671","DOIUrl":"https://doi.org/10.1111/bju.16671","url":null,"abstract":"","PeriodicalId":8985,"journal":{"name":"BJU International","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143063575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yubo Wang, Mingzhao Li, Kai Yao, Zhuyinjun Zong, Yifan Chang, Yongda Liu, Chao Cai, Fadi Mousa Al Kalailah, Shancheng Ren, Guohua Zeng, Di Gu
<p>For patients with locally advanced or high-risk localised prostate cancer who require lymph node dissection (LND), guidelines recommend an extended pelvic LND (ePLND). Such an extensive dissection ensures accurate staging information for most patients [<span>1</span>]. Advancements in surgical instrumentation and optimisation of surgical techniques could potentially empower surgeons to perform an ePLND in a more minimally invasive manner.</p><p>Extraperitoneal single-site or single-port robot-assisted radical prostatectomy (ESSRARP) has emerged as an intriguing concept. However, data from SSRARP with PLND studies have presented a less promising picture. The median number of lymph nodes (LNs) removed using the ESSRARP approach was only five [<span>2, 3</span>]. Compared with the transperitoneal anterior approach, the main difficulties for ePLND through an extraperitoneal approach are restricted workspace and a high incidence of symptomatic lymphocele [<span>4, 5</span>]. Exploring bridge technique is particularly interesting and appears to serve as good training for transitioning to the use of the single-port platform. Our primary aim in this study was to describe the surgical steps and technique of the ESSRARP with ePLND, along with the preliminary data.</p><p>Between June 2023 and December 2023, 31 patients underwent ESSRARP and ePLND (Table S1). The participants had a median age of 69 years and a median body mass index (BMI) of 21.71 kg/m<sup>2</sup>. The median (IQR) PSA level at biopsy was 32.10 (16.7–51.0) ng/mL. Overall, five (16.13%), and 26 (83.78%) patients had pathological Gleason score of 7, and 8–10, respectively. Five patients (16.13%) had LN metastasis detected by <sup>18</sup>F-prostate-specific membrane antigen positron emission tomography (PSMA PET)-CT.</p><p>The median (IQR) surgery duration and console time were 210 (185–226) min and 150 (136–170) min, respectively (Table S2). The median (IQR) estimated blood loss was 50 (40–50) mL. The (IQR) median number of LNs removed was 23 (18–29). Pathological LNI was diagnosed in seven patients (22.58%). Positive surgical margins were found in six (19.35%) patients.</p><p>Postoperative complications occurred in two patients (6.45%) (Table S3). One patient developed deep vein thrombosis requiring readmission, while the other developed acute epididymitis on postoperative Day 3, necessitating prolonged antibiotic therapy. No symptomatic lymphocele formation was observed (Table S3).</p><p>Our technique offers a valuable and timely alternative for urologists who lack access to dedicated single-port surgical systems. Our study achieved a median LN yield of 23, demonstrating a substantial improvement compared to prior research. It typically takes ~10 cases to complete the learning curve.</p><p>From the surgical technique standpoint, our approach maintained a distance between the camera and the surgical field, adjusting focus to maintain clarity. The shortened working arms of the robotic arms
{"title":"Extraperitoneal single-site robot-assisted radical prostatectomy with extended pelvic lymph node dissection: technique and experience","authors":"Yubo Wang, Mingzhao Li, Kai Yao, Zhuyinjun Zong, Yifan Chang, Yongda Liu, Chao Cai, Fadi Mousa Al Kalailah, Shancheng Ren, Guohua Zeng, Di Gu","doi":"10.1111/bju.16670","DOIUrl":"10.1111/bju.16670","url":null,"abstract":"<p>For patients with locally advanced or high-risk localised prostate cancer who require lymph node dissection (LND), guidelines recommend an extended pelvic LND (ePLND). Such an extensive dissection ensures accurate staging information for most patients [<span>1</span>]. Advancements in surgical instrumentation and optimisation of surgical techniques could potentially empower surgeons to perform an ePLND in a more minimally invasive manner.</p><p>Extraperitoneal single-site or single-port robot-assisted radical prostatectomy (ESSRARP) has emerged as an intriguing concept. However, data from SSRARP with PLND studies have presented a less promising picture. The median number of lymph nodes (LNs) removed using the ESSRARP approach was only five [<span>2, 3</span>]. Compared with the transperitoneal anterior approach, the main difficulties for ePLND through an extraperitoneal approach are restricted workspace and a high incidence of symptomatic lymphocele [<span>4, 5</span>]. Exploring bridge technique is particularly interesting and appears to serve as good training for transitioning to the use of the single-port platform. Our primary aim in this study was to describe the surgical steps and technique of the ESSRARP with ePLND, along with the preliminary data.</p><p>Between June 2023 and December 2023, 31 patients underwent ESSRARP and ePLND (Table S1). The participants had a median age of 69 years and a median body mass index (BMI) of 21.71 kg/m<sup>2</sup>. The median (IQR) PSA level at biopsy was 32.10 (16.7–51.0) ng/mL. Overall, five (16.13%), and 26 (83.78%) patients had pathological Gleason score of 7, and 8–10, respectively. Five patients (16.13%) had LN metastasis detected by <sup>18</sup>F-prostate-specific membrane antigen positron emission tomography (PSMA PET)-CT.</p><p>The median (IQR) surgery duration and console time were 210 (185–226) min and 150 (136–170) min, respectively (Table S2). The median (IQR) estimated blood loss was 50 (40–50) mL. The (IQR) median number of LNs removed was 23 (18–29). Pathological LNI was diagnosed in seven patients (22.58%). Positive surgical margins were found in six (19.35%) patients.</p><p>Postoperative complications occurred in two patients (6.45%) (Table S3). One patient developed deep vein thrombosis requiring readmission, while the other developed acute epididymitis on postoperative Day 3, necessitating prolonged antibiotic therapy. No symptomatic lymphocele formation was observed (Table S3).</p><p>Our technique offers a valuable and timely alternative for urologists who lack access to dedicated single-port surgical systems. Our study achieved a median LN yield of 23, demonstrating a substantial improvement compared to prior research. It typically takes ~10 cases to complete the learning curve.</p><p>From the surgical technique standpoint, our approach maintained a distance between the camera and the surgical field, adjusting focus to maintain clarity. The shortened working arms of the robotic arms","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"135 4","pages":"700-705"},"PeriodicalIF":3.7,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/bju.16670","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143056741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vincent J. Gnanapragasam, Alexandra Keates, Artitaya Lophatananon, Vineetha Thankapannair
To report 5-year outcomes from the STRATified CANcer Surveillance (STRATCANS) programme based on progression risks using National Institute for Health and Clinical Excellence (NICE) Cambridge Prognostic Group (CPG) at diagnosis, prostate specific antigen density and magnetic resonance imaging (MRI) visibility.
{"title":"The 5-year results of the Stratified Cancer Active Surveillance programme for men with prostate cancer","authors":"Vincent J. Gnanapragasam, Alexandra Keates, Artitaya Lophatananon, Vineetha Thankapannair","doi":"10.1111/bju.16666","DOIUrl":"https://doi.org/10.1111/bju.16666","url":null,"abstract":"To report 5-year outcomes from the STRATified CANcer Surveillance (STRATCANS) programme based on progression risks using National Institute for Health and Clinical Excellence (NICE) Cambridge Prognostic Group (CPG) at diagnosis, prostate specific antigen density and magnetic resonance imaging (MRI) visibility.","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"25 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143056495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nityam Rathi, Rabindra Gautam, Jason Hyman, Daniel Nethala, W. Marston Linehan, Mark W. Ball, Sandeep Gurram
{"title":"Growth kinetics of renal tumours during pregnancy in patients with hereditary renal cancer syndromes","authors":"Nityam Rathi, Rabindra Gautam, Jason Hyman, Daniel Nethala, W. Marston Linehan, Mark W. Ball, Sandeep Gurram","doi":"10.1111/bju.16593","DOIUrl":"10.1111/bju.16593","url":null,"abstract":"","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"135 4","pages":"591-593"},"PeriodicalIF":3.7,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143055305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maximilian Pallauf, Michael Rezaee, Roy Elias, Tina Wlajnitz, Sean A. Fletcher, Joseph Cheaib, Khalid Alkhatib, Peter Chang, Andrew A. Wagner, James M. McKiernan, Mohamad E. Allaf, Phillip M. Pierorazio, Nirmish Singla
To evaluate the association between tumour size and the growth rate (GR) of small renal masses (SRMs) in patients managed by active surveillance (AS).
{"title":"Tumour size is associated with growth rates of >0.5 cm/year and delayed intervention in small renal masses in patients on active surveillance","authors":"Maximilian Pallauf, Michael Rezaee, Roy Elias, Tina Wlajnitz, Sean A. Fletcher, Joseph Cheaib, Khalid Alkhatib, Peter Chang, Andrew A. Wagner, James M. McKiernan, Mohamad E. Allaf, Phillip M. Pierorazio, Nirmish Singla","doi":"10.1111/bju.16651","DOIUrl":"https://doi.org/10.1111/bju.16651","url":null,"abstract":"To evaluate the association between tumour size and the growth rate (GR) of small renal masses (SRMs) in patients managed by active surveillance (AS).","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"9 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143050808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ihtisham Ahmad, Dheidan Alshammari, Priyank Yadav, Michael Chua, Margarita Chancy, Mohd S. Ansari, Mohan S. Gundeti
Objective
To evaluate in a systematic review the outcomes, benefits, and limitations of robot-assisted surgeries for paediatric neurogenic lower urinary tract dysfunction (LUTD), as robot-assisted techniques have emerged as a potential alternative, offering enhanced precision, dexterity, and visualisation.
Methods
This review was registered in the International Prospective Register of Systematic Reviews (PROSPERO identifier CRD42023464849) and adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. We included studies of paediatric patients (aged <18 years) with neurogenic LUTD undergoing robot-assisted continence surgery, assessing safety and efficacy. Literature searches in the Medical Literature Analysis and Retrieval System Online (MEDLINE), Excerpta Medica dataBASE (EMBASE), and Scopus were conducted until 12 July 2024. Data extraction included surgical procedures, complications, operative times, lengths of stay, and bladder function outcomes.
Results
A total of 42 studies (20 case reports, 10 case series, six cohort studies, six comparative cohort studies) were included. Robotic procedures for continent catherisable channel construction, augmentation cystoplasty, and bladder neck reconstruction showed comparable peri- and postoperative outcomes. Meta-analysis of five studies comparing robotic vs open appendicovesicostomy indicated a significant reduction in length of stay for robotic groups, while operative time, complications, and re-intervention rates were not significantly different. Conversions to open surgery were rare, indicated by adhesions or small appendices during channel constructions.
Conclusions
Robot-assisted surgeries for paediatric neurogenic LUTD demonstrate potential benefits, including reduced hospital stays and comparable complication rates to open surgery in certain contexts. However, the available evidence is limited by heterogeneity in study designs, small sample sizes, and single-centre experiences, which constrain generalisability. Standardised reporting of complications and outcomes, alongside multicentre studies, is essential to clarify the long-term efficacy and broader applicability of these techniques.
{"title":"Robotic surgery for paediatric neurogenic lower urinary tract dysfunction: a systematic review","authors":"Ihtisham Ahmad, Dheidan Alshammari, Priyank Yadav, Michael Chua, Margarita Chancy, Mohd S. Ansari, Mohan S. Gundeti","doi":"10.1111/bju.16658","DOIUrl":"10.1111/bju.16658","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To evaluate in a systematic review the outcomes, benefits, and limitations of robot-assisted surgeries for paediatric neurogenic lower urinary tract dysfunction (LUTD), as robot-assisted techniques have emerged as a potential alternative, offering enhanced precision, dexterity, and visualisation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This review was registered in the International Prospective Register of Systematic Reviews (PROSPERO identifier CRD42023464849) and adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. We included studies of paediatric patients (aged <18 years) with neurogenic LUTD undergoing robot-assisted continence surgery, assessing safety and efficacy. Literature searches in the Medical Literature Analysis and Retrieval System Online (MEDLINE), Excerpta Medica dataBASE (EMBASE), and Scopus were conducted until 12 July 2024. Data extraction included surgical procedures, complications, operative times, lengths of stay, and bladder function outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 42 studies (20 case reports, 10 case series, six cohort studies, six comparative cohort studies) were included. Robotic procedures for continent catherisable channel construction, augmentation cystoplasty, and bladder neck reconstruction showed comparable peri- and postoperative outcomes. Meta-analysis of five studies comparing robotic vs open appendicovesicostomy indicated a significant reduction in length of stay for robotic groups, while operative time, complications, and re-intervention rates were not significantly different. Conversions to open surgery were rare, indicated by adhesions or small appendices during channel constructions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Robot-assisted surgeries for paediatric neurogenic LUTD demonstrate potential benefits, including reduced hospital stays and comparable complication rates to open surgery in certain contexts. However, the available evidence is limited by heterogeneity in study designs, small sample sizes, and single-centre experiences, which constrain generalisability. Standardised reporting of complications and outcomes, alongside multicentre studies, is essential to clarify the long-term efficacy and broader applicability of these techniques.</p>\u0000 </section>\u0000 </div>","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"135 4","pages":"557-566"},"PeriodicalIF":3.7,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/bju.16658","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143050839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bushra Abdelqader, Archie McGrath, Pinky Kotecha, John S McGrath, Joseph John
{"title":"Improving environmental sustainability in urology as a resident","authors":"Bushra Abdelqader, Archie McGrath, Pinky Kotecha, John S McGrath, Joseph John","doi":"10.1111/bju.16657","DOIUrl":"10.1111/bju.16657","url":null,"abstract":"","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"135 4","pages":"546-548"},"PeriodicalIF":3.7,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143050877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ivy Beeren, Hilde Meijer, Antoine G. van der Heijden, Katja K.H. Aben, J. Alfred Witjes, Lambertus A.L.M. Kiemeney, Alina Vrieling
To evaluate the association of pre- and post-diagnosis fluid intake with non-muscle-invasive bladder cancer (NMIBC) recurrence and progression risk.
{"title":"Fluid intake and recurrence and progression risk of patients with non-muscle-invasive bladder cancer","authors":"Ivy Beeren, Hilde Meijer, Antoine G. van der Heijden, Katja K.H. Aben, J. Alfred Witjes, Lambertus A.L.M. Kiemeney, Alina Vrieling","doi":"10.1111/bju.16665","DOIUrl":"https://doi.org/10.1111/bju.16665","url":null,"abstract":"To evaluate the association of pre- and post-diagnosis fluid intake with non-muscle-invasive bladder cancer (NMIBC) recurrence and progression risk.","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"58 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143031088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Victoria S. Edmonds, Daniel J. Heidenberg, Connor Mayes, Carolyn Mead-Harvey, Mitchell R. Humphreys
Objectives
To compare postoperative complication rates of patients with metabolic syndrome (MetS) with patients without MetS after holmium laser enucleation of the prostate (HoLEP) for management of benign prostatic hyperplasia (BPH).
Patients and Methods
We retrospectively reviewed patients aged >40 years who underwent HoLEP at our institution from 2007 to 2022. Criteria for MetS were diagnoses of at least three of the following: diabetes mellitus, hypertension, hyperlipidaemia, or obesity (body mass index ≥30 kg/m2). Uni- and multivariable logistic regression were used to compare the likelihood of immediate, 30-day, and 90-day complications between groups.
Results
A total of 1500 patients were included with a median (interquartile range) age of 70 (65–76) years. Patients with MetS were more likely to develop complications at both 30 and 90 days, including urinary incontinence, irritative voiding symptoms, and bleeding (P < 0.001). After adjusting for potential confounders, patients with MetS had a greater than three times odds of both 30- and 90-day complications compared to patients without MetS (30-day adjusted odds ratio [aOR] 3.32, 95% confidence interval [CI] 2.21–5.01, P < 0.001; and 90-day aOR 3.64, 95% CI 2.49–5.31, P < 0.001).
Conclusion
Metabolic syndrome was associated with a three-fold likelihood of 30- and 90-day complications after HoLEP. This could be an important factor to consider in preoperative counselling and patient selection.
{"title":"Metabolic syndrome is associated with postoperative complications after holmium laser enucleation of the prostate","authors":"Victoria S. Edmonds, Daniel J. Heidenberg, Connor Mayes, Carolyn Mead-Harvey, Mitchell R. Humphreys","doi":"10.1111/bju.16663","DOIUrl":"10.1111/bju.16663","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To compare postoperative complication rates of patients with metabolic syndrome (MetS) with patients without MetS after holmium laser enucleation of the prostate (HoLEP) for management of benign prostatic hyperplasia (BPH).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Patients and Methods</h3>\u0000 \u0000 <p>We retrospectively reviewed patients aged >40 years who underwent HoLEP at our institution from 2007 to 2022. Criteria for MetS were diagnoses of at least three of the following: diabetes mellitus, hypertension, hyperlipidaemia, or obesity (body mass index ≥30 kg/m<sup>2</sup>). Uni- and multivariable logistic regression were used to compare the likelihood of immediate, 30-day, and 90-day complications between groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 1500 patients were included with a median (interquartile range) age of 70 (65–76) years. Patients with MetS were more likely to develop complications at both 30 and 90 days, including urinary incontinence, irritative voiding symptoms, and bleeding (<i>P</i> < 0.001). After adjusting for potential confounders, patients with MetS had a greater than three times odds of both 30- and 90-day complications compared to patients without MetS (30-day adjusted odds ratio [aOR] 3.32, 95% confidence interval [CI] 2.21–5.01, <i>P</i> < 0.001; and 90-day aOR 3.64, 95% CI 2.49–5.31, <i>P</i> < 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Metabolic syndrome was associated with a three-fold likelihood of 30- and 90-day complications after HoLEP. This could be an important factor to consider in preoperative counselling and patient selection.</p>\u0000 </section>\u0000 </div>","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"135 4","pages":"684-690"},"PeriodicalIF":3.7,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143026434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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