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Five keys to stress reduction 减压的五个关键
Pub Date : 2017-03-21 DOI: 10.4172/2327-5162-C1-029
Kathy Gruver
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引用次数: 0
Safety of Chiropractic Spinal Manipulations: With a Review 脊椎按摩术的安全性:综述
Pub Date : 2017-03-20 DOI: 10.4172/2327-5162.1000233
A. T. Atayoğlu, A. Guner-Atayoglu, Gulcin Kuran-Cetinkale, M. A. Cetinkale
Healthcare providers do consider the potential risk of harm that any treatment can cause. Chiropractic healthcare is a system of complementary medicine based on the manipulative treatment of misalignments of the joints, especially those of the spinal column. Recently, the use of chiropractic spinal manipulation has increased considerably while its safety has been debated and estimates vary widely for the incidence of serious complications. Some vascular and neurological incidents account for the criticism surrounding chiropractic. The aim of this review is to investigate the risk of serious complications of chirporactic spinal manipulations to enlighten further understanding on their prevention.
医疗保健提供者确实考虑了任何治疗可能造成的潜在伤害风险。脊椎按摩保健是一种基于关节错位,特别是脊柱错位的手法治疗的补充医学系统。最近,脊骨神经医学脊柱手法的使用大幅增加,同时其安全性一直存在争议,严重并发症的发生率估计值差异很大。一些血管和神经系统事件引起了对脊骨神经医学的批评。这篇综述的目的是研究Chirporatic脊柱手法治疗严重并发症的风险,以启发对其预防的进一步理解。
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引用次数: 1
From East to West and Return : a Western Interpretation of Acupuncture 从东方到西方再到西方:针灸的西方诠释
Pub Date : 2017-03-17 DOI: 10.4172/2327-5162.1000234
E. Minelli, Bruna Francescucci, V. Toschi, S. Iotti, E. Malucelli, J. Maier
Acupuncture, a complementary therapy originated in China over 3000 years ago, is widely practiced in western countries. There is an urgent need to define the mechanisms underlying some clinical effects obtained by acupuncture. A placebo effect is sustained by neuroimaging evidence indicating the activation of areas in the brain that are involved in expectation after real and sham acupuncture. However, only real acupuncture modulates the activity of specific regions in the brain some of which involved in the perception of pain. Basic research applied to the field of acupuncture is beginning to offer a scientific interpretation to these events. Indeed, the stimulation of acupoints alters the architecture of the connective tissue and this local mechanical stress is delivered to the keratinocytes, mast cells and fibroblasts, which react in several manners, including the release of various molecules that act on peripheral nerve endings. Consequently, locally generated signals can be transmitted to the neural centers. In the light of these achievements and urging more research in the field, it can be concluded that there are common denominators between acupuncture and western medicine.
针灸是3000多年前起源于中国的一种辅助疗法,在西方国家得到广泛应用。目前迫切需要明确针刺获得的一些临床效果的机制。神经影像学证据表明,在真针灸和假针灸之后,大脑中与预期有关的区域被激活,从而证实了安慰剂效应。然而,只有真正的针灸才能调节大脑中特定区域的活动,其中一些区域与疼痛的感知有关。应用于针灸领域的基础研究开始为这些事件提供科学的解释。事实上,穴位的刺激改变了结缔组织的结构,这种局部的机械应力被传递给角化细胞、肥大细胞和成纤维细胞,它们以多种方式反应,包括释放作用于周围神经末梢的各种分子。因此,局部产生的信号可以传递到神经中枢。鉴于这些成果,并敦促在该领域进行更多的研究,可以得出结论,针灸与西医之间存在共同点。
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引用次数: 1
Homeopathy against Malaria: It ’s Potential as a Third Millennium Drug 抗疟疾顺势疗法:作为第三种千年药物的潜力
Pub Date : 2017-03-15 DOI: 10.4172/2327-5162.1000232
A. Rajan, R. Ravich, U. Bagai
Malaria is the most devastating infectious disease in the world, and increasing numbers of multi drug resistance parasites are making it worse. The rising problem of morbidity and mortality justify the search and adoption of new tools and measures to minimize the impact of malaria. World Health Organization stated that homoeopathy is the second most used medical system internationally which is a nontoxic form of alternative medicine and can be combined with classical treatment methods for avoiding the risk of adverse effects. Innumerous scientific researches have been carried out to sustain homoeopathy as a complete scientific system to combat antagonism. Establishment of classical homeopathic drugs for malaria can prove as a next generation therapy, as homeopathy doesn’t give any scope of resistance. The most important and significant aspect of homeopathic medicines is that they are developed after direct proving on human beings and not on animals. Each homeopathic medicine is therefore more akin to human nature and human system. This is a quality unshared by most medicines in other systems. This review will give scientific basis to classical homeopathic doctrine of ultra-high dilutions and their use as antimalarials. Homeopathic medicines are used against malaria since last two decades and this review provides a data of all homeopathic antimalarials and the ongoing researches. The review is supported by latest research in this field which can provide a base for designing better methodologies in the field of homeopathic antimalarial therapy.
疟疾是世界上最具破坏性的传染病,越来越多的耐多药寄生虫正在使情况恶化。发病率和死亡率问题日益严重,有理由寻求和采用新的工具和措施,尽量减少疟疾的影响。世界卫生组织指出,顺势疗法是国际上第二大使用的医疗系统,它是一种无毒的替代医学形式,可以与传统的治疗方法相结合,以避免不良反应的风险。无数的科学研究支持顺势疗法作为一个完整的科学体系来对抗对抗。由于顺势疗法不会产生任何抗药性,因此建立经典的顺势疗法治疗疟疾的药物可以证明是下一代疗法。顺势疗法药物最重要和最重要的方面是,它们是在人类而不是动物身上直接证明后开发出来的。因此,每一种顺势疗法药物都更接近于人性和人体系统。这是其他系统中大多数药物所不具备的品质。本文综述将为传统顺势疗法的超高稀释度理论及其抗疟应用提供科学依据。近二十年来,顺势疗法药物被用于治疗疟疾,本综述提供了所有顺势疗法抗疟药物和正在进行的研究的数据。本文综述以该领域的最新研究成果为依据,为顺势疗法抗疟治疗方法的设计提供依据。
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引用次数: 1
Brief Review on the Causes, Diagnosis and Therapeutic Treatment of Gastritis Disease 胃炎的病因、诊断与治疗综述
Pub Date : 2017-02-20 DOI: 10.4172/2327-5162.1000231
M. Elseweidy
Gastritis represent a state of inflammation, irritation, or erosion of the stomach lining which may occur suddenly (acute) or gradually (chronic). Generally there is no universally accepted classification of gastritis and early classification was based mainly on the morphology, but recently pathogenic mechanisms have also been incorporated. The gastric mucosa is continuously exposed to many noxious factors, and Gastric protection aimed mainly to reduce or prevent the chemically induced acute hemorrhagic erosions which is exerted by compounds such as prostaglandins (PG) and SH derivatives without inhibiting acid secretion. Common causes of gastritis are excessive alcohol consumption or prolonged use of non-steroidal antiinflammatory drugs (NSAIDs) such as aspirin or ibuprofen. It may also develop after major surgery, traumatic injury, burns, or severe infections. Chronic causes are infection with bacteria, primarily Helicobacter pylori (HP), chronic bile reflux, stress additionally certain autoimmune disorders can cause gastritis as well. The most common symptom is abdominal upset or pain, indigestion, abdominal bloating, nausea, vomiting and pernicious anemia. The current study here is focusing on the causes, clinical profile, inflammatory, immune response and autoimmune atrophic gastritis in affected individuals. Additional focuses are on different diagnostic tools for Helicobacter pylori infection (HP) and current therapeutic treatment.
胃炎表现为一种炎症、刺激或胃粘膜糜烂的状态,可突然发生(急性)或逐渐发生(慢性)。胃炎的分类一般没有统一的分类方法,早期的分类主要基于形态学,但近年来也纳入了致病机制。胃粘膜持续暴露于多种有害因素,胃保护主要是减少或防止化学诱导的急性出血性糜烂,这种糜烂是由前列腺素(PG)和SH衍生物等化合物造成的,而不抑制酸的分泌。胃炎的常见原因是过度饮酒或长期使用非甾体抗炎药(NSAIDs),如阿司匹林或布洛芬。它也可能发生在大手术、外伤、烧伤或严重感染后。慢性原因是细菌感染,主要是幽门螺杆菌(HP),慢性胆汁反流,压力,此外某些自身免疫性疾病也可引起胃炎。最常见的症状是腹部不适或疼痛,消化不良,腹胀,恶心,呕吐和恶性贫血。目前的研究重点是萎缩性胃炎的病因、临床特征、炎症、免疫反应和自身免疫性胃炎。另外的重点是幽门螺杆菌感染(HP)的不同诊断工具和目前的治疗方法。
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引用次数: 6
Acupuncture Regulates the Notch Signaling Pathway in Bone Marrow Cells to Alleviate Cyclophosphamide-Induced Myelosuppression in S180 Tumor Bearing Mice 针刺调节骨髓细胞Notch信号通路缓解环磷酰胺诱导的S180荷瘤小鼠骨髓抑制
Pub Date : 2017-02-20 DOI: 10.4172/2327-5162.1000229
Mei Lu, Dong-dong Yu, Da-ming Cao, Yingchun Teng, Jianwei Li, Guanan Wang, Yan-Chun Wang, Li Zhang
Objective: To evaluate the protein expression and distribution of Notch signaling-related, differentially expressed genes (DEGs) in the bone marrow cells of S180 tumor bearing mice. Additionally, verification of acupuncture regulated protein expression of these DEGs to protect bone marrow stem cells and alleviate cyclophosphamide (CTX) chemotherapy-induced myelosuppression was examined as well. Methods: Healthy male Kunming mice were inoculated with S180 sarcomas and further divided into blank control (group A), CTX group (group B), acupuncture (group C), and moxibustion (group D) groups. Animals in groups B, C, and D were intraperitoneally injected with single dose of 150 mg/kg CTX to generate the myelosuppressive model; while animals in group A were injected with an equivalent volume of sterile saline. After immobilizing the animals, mice in groups C and D received daily acupuncture and moxibustion, respectively at Dazhui, Geshu, Shenshu, and Zusanli acupoints; while mice in groups A and B received no daily treatment. Animals in each group were euthanized by cervical dislocation following five days of treatment and their femurs collected for marrow harvest. Small-throughput cDNA microarray was used for initial DEG screening, followed by immunohistochemistry, real-time quantitative PCR (RT-qPCR), and Western Blot analysis to detect protein expression and quantity of the Notch signaling-related DEGs in the bone marrow cells. Results: Expression of numb proteins (i.e., numb1 and numb2) was found to be up regulated while notch2 and jag1 were down regulated in bone marrow cells of acupuncture treated, tumor bearing mice. Conclusion: Acupuncture regulated the changes of Notch signaling-related DEGs in mouse bone marrow cells. The data indicates that acupuncture treatment may alleviate the CTX chemotherapy-induced myelosuppression associated with tumor burden, suggesting that might be the key mechanism to improve bone marrow function.
目的:评价Notch信号传导相关差异表达基因(DEGs)在S180荷瘤小鼠骨髓细胞中的蛋白表达和分布。此外,还验证了针刺调节这些DEG的蛋白表达以保护骨髓干细胞和减轻环磷酰胺(CTX)化疗诱导的骨髓抑制。方法:健康雄性昆明小鼠接种S180肉瘤,并进一步分为空白对照组(A组)、CTX组(B组)、针灸组(C组)和艾灸组(D组)。B、C和D组的动物腹膜内注射单剂量150mg/kg CTX以产生骨髓抑制模型;而A组的动物被注射等量的无菌盐水。固定动物后,C组和D组小鼠分别在大椎、格书、肾俞和足三里穴位进行每日针灸;而A组和B组的小鼠不接受每日治疗。每组动物在治疗五天后通过颈椎脱位实施安乐死,并采集其股骨进行骨髓采集。使用小通量cDNA微阵列进行DEG的初步筛选,然后进行免疫组织化学、实时定量PCR(RT-qPCR)和Western印迹分析,以检测骨髓细胞中Notch信号相关DEG的蛋白质表达和数量。结果:在针刺治疗的荷瘤小鼠的骨髓细胞中,发现麻木蛋白(即麻木1和麻木2)的表达上调,而notch2和jag1的表达下调。结论:针刺可调节小鼠骨髓细胞Notch信号传导相关DEGs的变化。数据表明,针灸治疗可以减轻CTX化疗诱导的与肿瘤负荷相关的骨髓抑制,这可能是改善骨髓功能的关键机制。
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引用次数: 1
The Joint Moment Distribution of the Lower Extremity During Tai Chi Gait 太极拳步态中下肢关节力矩分布的研究
Pub Date : 2017-02-10 DOI: 10.4172/2327-5162.1000228
R. Pearlman, J. Kovaleski, Jonathan Wolfe, Wei Liu
Background: As an alternative and complementary practice, Tai Chi is becoming increasingly popular in the United States, especially among the elderly. Although several interventional and qualitative biomechanical studies have been performed, a quantitative approach, such as multi-joints kinetics synergy of ankle, knee and hip, has yet to be performed. To better understand the biomechanics of Tai Chi, the characteristics of the total support moment synergy were studied during Tai Chi gait and compared to normal gait. Methods: Ten healthy, experienced (two years) Tai Chi Chuan practitioners performed normal walking and Tai Chi gait while data was collected using high-speed infrared motion analysis cameras. The joint distributions of the ankle, knee, and hip were calculated by ratio between individual joint moment impulse and total support moment impulse. Using a paired t-test, the joint moment distributions of the lower limb were compared between Tai Chi gait and normal walking. Results: The total support moment of Tai Chi walking was predominated by the contribution of the knee (ankle: 32.78 ± 1.25%; knee: 58.68 ± 1.84%; hip: 8.54 ± 1.91%) whereas the ankle was the primary contributor to support in normal walking (ankle: 67.86 ± 2.76%; knee: 26.18 ± 2.69%; hip: 5.96 ± 1.83%). The contributions of all three joints studied differed significantly (p<0.05) between Tai Chi gait and normal gait. Conclusion: This study demonstrates different kinetics synergy patterns between Tai Chi gait and normal gait. Importantly, Tai Chi gait places a high mechanical demand on the knee joint. Our results provide biomechanical basis of Tai Chi’s benefits on increasing knee joint range of motion and muscle strength, also suggest that prescribing Tai Chi as a potential therapy for people with joint disease, it needs a careful consideration of evaluating mechanical response of people with joint disease during Tai Chi exercise due to higher mechanical demand on the knee joint.
背景:作为一种替代和补充练习,太极拳在美国越来越受欢迎,尤其是在老年人中。虽然已经进行了一些介入性和定性的生物力学研究,但定量方法,如踝关节、膝关节和髋关节的多关节动力学协同作用,尚未进行。为了更好地理解太极拳的生物力学,研究了太极拳步态中总支撑力矩协同的特征,并与正常步态进行了比较。方法:10名健康、有经验(2年)的太极拳练习者进行正常行走和太极拳步态,并使用高速红外运动分析摄像机收集数据。通过单个关节力矩冲量与总支撑力矩冲量之比计算踝关节、膝关节和髋关节的关节分布。采用配对t检验,比较太极拳步态与正常行走的下肢关节力矩分布。结果:太极拳行走的总支撑力矩以膝关节(踝关节:32.78±1.25%;膝关节:58.68±1.84%;髋关节:8.54±1.91%),而踝关节是正常行走时主要的支撑因素(踝关节:67.86±2.76%;膝关节:26.18±2.69%;髋部:5.96±1.83%)。太极拳步态与正常步态对三个关节的贡献差异有统计学意义(p<0.05)。结论:本研究显示太极拳步态与正常步态的动力学协同模式不同。重要的是,太极拳步态对膝关节的机械要求很高。我们的研究结果为太极拳对增加膝关节活动范围和肌肉力量的益处提供了生物力学基础,也提示太极拳作为关节疾病患者的潜在治疗方法,由于对膝关节的机械要求较高,需要仔细考虑评估关节疾病患者在太极拳运动期间的机械反应。
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引用次数: 0
Suitability for Consumption of Chyawanprakash-A Herbal Formulation in Controlled Type II Diabetics-A Open Label Clinical Study chyawanprakash -一种草药制剂在控制型糖尿病患者中的适宜性——一项开放标签临床研究
Pub Date : 2017-02-02 DOI: 10.4172/2327-5162.1000230
Satyendra Kumar, Arun Gupta, Raman Ghungralekar, V. Deshpande
Objective: Chyawanprakash, a Chyawanprash based proprietary Ayurvedic formulation in which conventional sugar and honey are replaced by permitted alternate sweeteners in diabetic population. Design: This was a randomized open label clinical study conducted across two study sites in Maharashtra (India). 121 male and female subjects in the age range of 18-70 years who were suffering from Type II Diabetes mellitus for more than one year and were stabilized on either exercise/diet regimen or oral hypoglycemic agents were recruited in the study and advised 1 teaspoonful of Chyawanprakash twice daily orally after meals for 90 days. They were advised to continue their anti-diabetic medicines under the supervision of the Investigator. Results were assessed basis pre and post treatment changes in glycosyated hemoglobin (HbA1c) and the Physician global assessment of overall safety. Clinical symptoms, laboratory parameters like blood sugar and insulin levels, microalbuminuria, liver and renal function tests, lipid profiles etc and changes in dose of oral hypoglycemic agents were also assessed. Results: Oral administration of Chyawanprakash in recommended dosage in controlled Type II diabetics did not show any safety concern which was evident by no statistically significant change in HbA1c levels and the clinical as well as laboratory parameters (blood sugar, microalbuminuria, liver and renal function tests, lipid profiles etc). 97% excellent safety was reported on the Physician’s global assessment of overall safety. Moreover, a statistically significant improvement was also observed in energy levels of subjects. Conclusion: Results concluded the suitability of Chyawanprakash in controlled Type II diabetics.
目的:Chyawanprakash,一种基于Chyawanprash的专有阿育吠陀配方,在糖尿病人群中,传统的糖和蜂蜜被允许的替代甜味剂取代。设计:这是一项随机开放标签临床研究,在马哈拉施特拉邦(印度)的两个研究地点进行。本研究招募了121名年龄在18-70岁之间的男性和女性受试者,他们患有II型糖尿病超过一年,并且在运动/饮食方案或口服降糖药方面病情稳定,并建议他们在90天内每天两次口服1茶匙恰万普拉卡。建议他们在研究者的监督下继续服用抗糖尿病药物。根据治疗前和治疗后糖化血红蛋白(HbA1c)的变化以及医师对总体安全性的全球评估来评估结果。还评估了临床症状、实验室参数,如血糖和胰岛素水平、微量白蛋白尿、肝肾功能测试、脂质状况等,以及口服降糖药剂量的变化。结果:对照II型糖尿病患者按推荐剂量口服Chyawanprakash没有显示出任何安全性问题,HbA1c水平、临床和实验室参数(血糖、微量白蛋白尿、肝肾功能测试、脂质状况等)没有明显的统计学显着变化。医师对总体安全性的全球评估报告了97%的优良安全性。此外,受试者的能量水平也有统计学上的显著改善。结论:结果表明Chyawanprakash在Ⅱ型糖尿病患者中的适用性。
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引用次数: 4
Music Therapy: Creating Harmony Amidst the Dissonance of Cancer 音乐治疗:在癌症的失调中创造和谐
Pub Date : 2017-02-02 DOI: 10.4172/2327-5162.1000227
J. Palmer
Cancer diagnoses often carry with them a range of emotional distress. The evidence based, complimentary medicine practice of music therapy may improve patient symptoms, care and quality of life. This paper will present 3 case studies to illustrate the effect music therapy can potentially have on the lives of cancer patients. Music therapy may serve as a beneficial and cost-effective adjunct to standard oncology care and it is suggested that music therapy practices be considered at hospitals and oncology centers nationally.
癌症的诊断通常伴随着一系列的情绪困扰。音乐疗法的循证医学实践可以改善患者的症状、护理和生活质量。本文将介绍3个案例研究,以说明音乐疗法可能对癌症患者的生活产生的潜在影响。音乐治疗可能是标准肿瘤学护理的一种有益且具有成本效益的辅助手段,建议在全国各地的医院和肿瘤中心考虑音乐治疗实践。
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引用次数: 0
Observing Behavioral Effects in Mini-Pigs after Blocking the Low Hydraulic Resistance Channels along the Stomach Meridian 阻断胃经低水力阻力通道对小型猪行为影响的观察
Pub Date : 2017-01-01 DOI: 10.4172/2327-5162.1000251
Wei Bo Zhang, Wenting Zhou, Guangjun Wang, Shuyong Jia, Yu-ying Tian, Xiaojing Song, Hongyan Li
Objective: To study the relationship between the meridian and diseases by establishing a pathological model and study the effects of blocked channels on the behavior of mini-pigs. Method: First, we measured the low electrical impedance line along the stomach meridian. Next we measured the hydraulic resistance (HR) around the meridian to find points with the lowest HR. Gel were then injected into the points to establish a model for “blocked meridian”. A control group was injected with saline. The behaviors of the mini-pigs were observed. The video was then reviewed and frequency of climbing fence in the dtime (FCFD) and frequency of nighttime activity (FNA) were analyzed. Results: When the mean values in various time periods were compared, there was no significant difference between the two groups in the two markers. However, over time, the model group exhibited an upward trend of FCFD which had a correlation coefficient of 0.868 with the modeling ds, i.e. the ds elapsed after establishing the model which was statistically significant. The control group, was -0.045, which was not statistically significant. There was a similar tendency for FNA over time that the correlation coefficient between FNA and modeling ds was 0.675 (P 0.1). Conclusion: Blocking LHRC along stomach meridian produces behavioral changes that are consistent with the pathological symptoms of stomach meridian. These changes are directly correlated with the modeling ds and gradually become more pronounced with the passage of time.
目的:通过建立病理模型,研究经络与疾病的关系,研究经络不通对迷你猪行为的影响。方法:首先沿胃经测量低电阻抗线。接下来,我们测量了子午线周围的水力阻力(HR),以找到HR最低的点。然后将凝胶注入穴位,建立“经络不通”模型。对照组注射生理盐水。观察迷你猪的行为。然后回顾视频,分析白天爬栅栏频率(FCFD)和夜间活动频率(FNA)。结果:比较各时间段的平均值,两组间两项指标均无显著差异。但随着时间的推移,模型组FCFD呈上升趋势,与建模ds的相关系数为0.868,即建立模型后经过的ds有统计学意义。对照组为-0.045,差异无统计学意义。FNA随时间的变化趋势相似,FNA与模型ds的相关系数为0.675 (p0.1)。结论:沿胃经阻断LHRC可产生与胃经病理症状一致的行为改变。这些变化与建模ds直接相关,并随着时间的推移逐渐变得更加明显。
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引用次数: 0
期刊
Alternative & integrative medicine
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