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Strategies for creating undergraduate research and outreach experiences. 创造本科生研究和拓展经验的策略。
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2025-06-24 DOI: 10.1186/s12919-025-00334-4
Fadie T Coleman, Danielle E Graham

Engaging students in research and outreach offers a range of benefits, including acquiring scientific knowledge and critical skills, fostering science identity development and increasing persistence in science, and providing broad exposure to STEM careers. Although undergraduate research experiences have been shown to be impactful for developing scientists, exploring ways in which all students can experience these opportunities is an important focus that merits continued discussion. This paper will discuss ways in which well-known strategies for incorporating research into science curricula can be further adapted to have a broader impact on undergraduate education and science outreach programming. In addition, key insights inspired by an "Adapting Your Research for Teaching and Outreach" workshop will be considered. Lastly, this paper will discuss ways in which inclusive strategies can facilitate practical application across diverse educational settings.

让学生参与研究和推广提供了一系列好处,包括获得科学知识和关键技能,促进科学认同的发展和对科学的坚持,以及提供广泛的STEM职业机会。尽管本科生的研究经历已被证明对发展中的科学家有影响,但探索让所有学生都能体验这些机会的方法是一个值得继续讨论的重要焦点。本文将讨论将研究纳入科学课程的众所周知的策略可以进一步适应对本科教育和科学推广规划产生更广泛影响的方法。此外,将考虑从“使您的研究适应教学和推广”研讨会中获得的关键见解。最后,本文将讨论包容性战略如何促进在不同教育环境中的实际应用。
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引用次数: 0
One Health Gathering: Arctic Indigenous Peoples Voices and Perspectives. 一次健康聚会:北极土著人民的声音和观点。
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2025-06-16 DOI: 10.1186/s12919-025-00329-1
G K Healey Akearok, C V L Larsen

The proceedings of the One Health Gathering in Iqaluit, Nunavut, Canada, centered on the theme of "Elevating Indigenous Voices in One Health Research in the Arctic." Approximately fifty participants from Greenland, the USA, Canada, and across Nunavut's three regions convened to explore key aspects of research pertinent to this theme. The gathering underscored Indigenous Knowledge and Practices, emphasizing innovative post-secondary education models rooted in Inuit ways of knowing. It also delved into Holistic Worldviews and Health and Wellbeing, spotlighting community country food programs, harvesting practices, and the significance of holistic perspectives in healthcare. Local contexts and community voices were prioritized, with presentations showcasing community-led testing for a parasite in walrus, co-management programs for polar bears, and the vital role of student voices and perspectives. Elder stories and wisdom were shared, adding invaluable insight and depth to discussions. Moreover, the gathering fostered community empowerment and action on One Health research and/or policy, culminating in collaborative recommendations and an art piece aimed at amplifying community engagement and agency in research initiatives. Overall, the event provided a platform for diverse voices to converge, exchange knowledge, and collaborate towards a more inclusive and effective approach to One Health research in the Arctic, reflecting a commitment to Indigenous perspectives, community empowerment, and holistic wellbeing.

在加拿大努纳武特伊魁特举行的一次健康聚会的会议记录集中讨论了“在北极的一次健康研究中提高土著声音”的主题。来自格陵兰、美国、加拿大和努纳武特三个地区的大约50名与会者召开会议,探讨与这一主题相关的研究的关键方面。会议强调土著知识和实践,强调基于因纽特人认知方式的创新中学后教育模式。它还深入研究了整体世界观和健康与福祉,重点关注社区乡村食品计划,收获实践以及整体观点在医疗保健中的重要性。当地情况和社区的声音被优先考虑,展示了社区主导的海象寄生虫测试,北极熊的共同管理项目,以及学生声音和观点的重要作用。大家分享了长者的故事和智慧,为讨论增添了宝贵的见解和深度。此外,这次会议促进了社区在“同一个健康”研究和/或政策方面的赋权和行动,最终提出了协作建议和一件艺术品,旨在扩大社区参与和机构参与研究倡议。总的来说,这次活动为不同的声音提供了一个平台,让他们汇聚一堂,交流知识,并合作,以一种更具包容性和更有效的方法来开展北极地区的“同一个健康”研究,反映了对土著观点、社区赋权和整体福祉的承诺。
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引用次数: 0
Advancing care priorities for health and quality of life among older adults in the autism and/or intellectual disabilities communities: proceedings of an international Think Tank. 促进自闭症和/或智力残疾社区老年人健康和生活质量的护理优先事项:国际智库会议录。
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2025-06-16 DOI: 10.1186/s12919-025-00330-8
David B Nicholas, Fakhri Shafai, Stephen M Edelson, Vanessa Bal, Hilary Nelson, Wenn Lawson, Mary Doherty, Hilde M Geurts, William F Sullivan, B Blair Braden, Gregory L Wallace, Maxine Share, Laura St John, David G Amaral, Agnes H Whitaker, Lori Watters, Terri Robson, Joanne Gauthier, Sylvère Moulanier, Linda Perry, Sandy Stemp, Ellen Wilkinson, Nancy Jokinen, Margaret L Bauman, Robert Hendren, Evdokia Anagnostou, Julian N Trollor

As the number of older autistic adults and adults with intellectual disabilities grows, expanding capacity to meet their needs is crucial. On November 23-25, 2023, a Think Tank on aging in autism and/or intellectual disabilities was convened, with national and international delegates within this field. The Think Tank consisted of presentations focusing on key issues as well as a series of panel presentations addressing first-person lived experience, family caregiving, service provision in the community, and physical and mental health-based care. Discussion reflected lived experiences and care needs in this population, with an ultimate aim of advancing healthcare and community support. Delegates, who represent perspectives as self-advocates, family caregivers, service providers, clinicians and researchers, ranked guidelines and areas of focus identified in the literature in terms of the most important priorities for the near-term development of capacity building resources.

随着老年自闭症成年人和智力残疾成年人数量的增加,扩大满足他们需求的能力至关重要。2023年11月23日至25日,一个关于自闭症和/或智力残疾老龄化的智库召开了会议,该领域的国家和国际代表参加了会议。该智库包括集中讨论关键问题的演讲,以及一系列关于第一人称生活体验、家庭护理、社区服务提供以及基于身心健康的护理的小组演讲。讨论反映了这一人群的生活经历和护理需求,最终目的是促进医疗保健和社区支持。代表自我倡导者、家庭照顾者、服务提供者、临床医生和研究人员等观点的代表们,根据近期能力建设资源开发的最重要优先事项,对文献中确定的指导方针和重点领域进行了排名。
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引用次数: 0
Abstracts from the Globesync Community Research and Sustainability (GlobeCoReS 2024). Globesync社区研究与可持续发展(GlobeCoReS 2024)摘要。
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2025-06-11 DOI: 10.1186/s12919-025-00325-5
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引用次数: 0
The silent epidemic of non-adherence - insights from the 2024 a:care congress. 不依从的无声流行——来自2024年a:护理大会的见解。
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2025-05-22 DOI: 10.1186/s12919-025-00326-4
Sheri D Pruitt, Rabia Khan, Nathorn Chaiyakunapruk, Arintaya Phrommintikul, Miguel Angel Díaz Aguilera, Ngiap Chuan Tan, Shoaib Afzal, Andressa da Silva van der Laan, John Weinman

Medication non-adherence is a global challenge with profound implications for patient health outcomes, healthcare systems, and society at large. This widespread issue leads to hundreds of thousands of preventable deaths and hospitalizations annually, and billions of dollars in avoidable healthcare costs. No country is immune to this challenge. The a:care Congress 2024, titled "Adherence is a Behavior: Do We Have the Right One?", addressed this critical issue to understand its societal and economic burden and explore the complex human behaviors driving it. The Congress examined the global impact of non-adherence and local realities, providing a health economic perspective on its consequences. Behavioral factors influencing adherence were analyzed, emphasizing the importance of understanding individual patient motivations. The role of technology and artificial intelligence in the physician-patient relationship was discussed, highlighting opportunities and challenges of integrating these tools. The patient's voice was brought to the forefront, underscoring the importance of communication and trust in the care relationship. A final multidisciplinary session explored the role of each stakeholder in improving adherence. This article provides an overview of the different sessions from the congress, focusing on the challenges associated with medication non-adherence and potential solutions. It emphasizes the need for a multidimensional approach involving all healthcare system stakeholders and the importance of prioritizing the development of new strategies to improve overall health outcomes and healthcare system efficiency.

药物不依从是一个全球性的挑战,对患者的健康结果、卫生保健系统和整个社会都有着深远的影响。这一广泛的问题每年导致成千上万的可预防的死亡和住院,以及数十亿美元的可避免的医疗费用。任何国家都不能幸免于这一挑战。2024年的a:care大会,题为“坚持是一种行为:我们是否有正确的行为?”,解决了这一关键问题,以了解其社会和经济负担,并探索推动它的复杂人类行为。大会审查了不遵守《公约》的全球影响和当地现实情况,从卫生经济角度看待其后果。我们分析了影响依从性的行为因素,强调了了解患者个体动机的重要性。讨论了技术和人工智能在医患关系中的作用,强调了整合这些工具的机遇和挑战。病人的声音被放在最重要的位置,强调了在护理关系中沟通和信任的重要性。最后的多学科会议探讨了每个利益相关者在提高依从性方面的作用。本文概述了大会的不同会议,重点关注与药物依从性相关的挑战和潜在的解决方案。它强调需要采取涉及所有卫生保健系统利益攸关方的多维方法,以及优先制定新战略以改善总体卫生结果和卫生保健系统效率的重要性。
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引用次数: 0
Negotiating an academic start-up package and job offer as an incoming tenure-track professor in the life sciences. 谈判学术启动计划和即将成为生命科学终身教授的工作机会。
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2025-05-16 DOI: 10.1186/s12919-025-00327-3
Leslie A Caromile, Verónica A Segarra

Start-up packages were once predominantly associated with research-intensive institutions. However, they are now increasingly important for teaching-focused and primarily undergraduate institutions due to rising expectations for research involvement. Effective negotiation for tenure-track start-up packages is essential for aligning the candidates' and institutions' interests and goals. Candidates must understand the various components of an offer, such as start-up funds, teaching loads, research expectations, and tenure requirements, to negotiate terms that align with their needs and goals. However, navigating these negotiations can be daunting, particularly for individuals from historically underserved and excluded groups (HUE) in STEM fields who may lack access to supportive networks. In this article, we aim to provide a detailed guide on how to negotiate an effective tenure-track start-up package. We emphasize that this process can be beneficial for both the candidate and the institution, as it helps ensure that their values and goals are aligned, ultimately increasing the chances of success for both parties. This article builds upon our earlier publications and provides comprehensive guidance for negotiating strategies.

启动包曾经主要与研究密集型机构联系在一起。然而,由于对研究参与的期望越来越高,它们现在对以教学为重点的本科院校越来越重要。就终身职位创业计划进行有效的谈判,对于协调候选人和机构的利益和目标至关重要。候选人必须了解报价的各个组成部分,如启动资金、教学负荷、研究期望和任期要求,以便与他们的需求和目标协商一致的条款。然而,引导这些谈判可能令人望而生畏,特别是对于来自STEM领域历史上服务不足和被排斥群体(HUE)的个人来说,他们可能无法获得支持网络。在这篇文章中,我们的目标是提供一个关于如何谈判一个有效的终身轨道启动包的详细指导。我们强调,这一过程对候选人和机构都是有益的,因为它有助于确保他们的价值观和目标一致,最终增加双方成功的机会。本文建立在我们早期出版物的基础上,为谈判策略提供了全面的指导。
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引用次数: 0
Data integration and synthesis for pandemic and epidemic intelligence. 流行病和流行病情报的数据集成和综合。
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2025-04-23 DOI: 10.1186/s12919-025-00321-9
Barbara Tornimbene, Zoila Beatriz Leiva Rioja, Manoel Barral-Netto, Carlos Castillo-Salgado, Irena Djordjevic, Moritz Kraemer, Martina McMenamin, Oliver Morgan

The COVID-19 pandemic highlighted substantial obstacles in real-time data generation and management needed for clinical research and epidemiological analysis. Three years after the pandemic, reflection on the difficulties of data integration offers potential to improve emergency preparedness. The fourth session of the WHO Pandemic and Epidemic Intelligence Forum sought to report the experiences of key global institutions in data integration and synthesis, with the aim of identifying solutions for effective integration. Data integration, defined as the combination of heterogeneous sources into a cohesive system, allows for combining epidemiological data with contextual elements such as socioeconomic determinants to create a more complete picture of disease patterns. The approach is critical for predicting outbreaks, determining disease burden, and evaluating interventions. The use of contextual information improves real-time intelligence and risk assessments, allowing for faster outbreak responses. This report captures the growing acknowledgment of data integration importance in boosting public health intelligence and readiness and show examples of how global institutions are strengthening initiatives to respond to this need. However, obstacles persist, including interoperability, data standardization, and ethical considerations. The success of future data integration efforts will be determined by the development of a common technical and legal framework, the promotion of global collaboration, and the protection of sensitive data. Ultimately, effective data integration can potentially transform public health intelligence and our way to successfully respond to future pandemics.

2019冠状病毒病大流行凸显了临床研究和流行病学分析所需的实时数据生成和管理方面的重大障碍。大流行过去三年后,对数据整合困难的反思为改进应急准备工作提供了潜力。世卫组织大流行病和流行病情报论坛第四届会议力求报告全球主要机构在数据整合和综合方面的经验,目的是确定有效整合的解决办法。数据整合的定义是将异质来源组合成一个有凝聚力的系统,它允许将流行病学数据与社会经济决定因素等背景因素结合起来,以更全面地了解疾病模式。该方法对于预测疫情、确定疾病负担和评估干预措施至关重要。使用上下文信息可改善实时情报和风险评估,从而加快疫情应对。本报告反映了人们日益认识到数据整合在提高公共卫生情报和准备方面的重要性,并举例说明了全球机构如何加强应对这一需求的举措。然而,障碍仍然存在,包括互操作性、数据标准化和道德考虑。未来数据整合工作的成功将取决于共同技术和法律框架的发展、全球合作的促进以及敏感数据的保护。最终,有效的数据整合有可能改变公共卫生情报和我们成功应对未来流行病的方式。
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引用次数: 0
Proceedings of the 2nd edition of the International e-Health Forum 2024. 2024年第二届国际电子卫生论坛论文集。
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2025-04-15 DOI: 10.1186/s12919-025-00324-6
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引用次数: 0
Lessons learned from Café Scientifique public webinars on pregnancy and parenting in arthritis: perspectives from patients, clinicians, and researchers. 从caf<s:1>科学公共网络研讨会中获得的关于关节炎的怀孕和养育的经验教训:来自患者,临床医生和研究人员的观点。
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2025-04-08 DOI: 10.1186/s12919-025-00323-7
Vienna Cheng, Preet Kang, Laurie Proulx, Neda Amiri, Mary A De Vera

Background: Arthritis is a group of chronic inflammatory conditions, including systemic lupus erythematosus and rheumatoid arthritis, that disproportionately impact females more than men, often during the childbearing years. Challenges with pregnancy and parenting continue to significantly impact patients and families living with arthritis, compounded by the historical lack of research that has hindered the ability to make informed family planning decisions.

Objectives: In ongoing efforts to broadly translate our expanding research findings in this area, we held two public webinars on pregnancy and parenting in arthritis with the following goals: 1) to create forums for discussion among researchers, patients, and clinicians; 2) raise awareness on emerging issues requiring future research; and 3) provide evidence-based, practical advice for patients, caregivers and families. The first webinar on Pregnancy and Arthritis united perspectives from patients, clinicians and researchers. We learned firsthand challenges of navigating pregnancy with arthritis from patients of various backgrounds, including those who highlighted longstanding healthcare disparities. A rheumatologist specializing in pregnancy and reproductive health shared insights, concluding with the positive outlook that perinatal research is underway on emerging antirheumatic therapies. The second webinar on Parenting and Arthritis discussed evidence-based resources and strategies to support parents, integrating insights from researchers and clinicians.

Conclusion: These webinars illuminated the profound impacts of arthritis on patients and families and revealed knowledge gaps for future research.

背景:关节炎是一组慢性炎症性疾病,包括系统性红斑狼疮和类风湿关节炎,对女性的影响大于男性,通常发生在育龄期。怀孕和养育孩子的挑战继续对关节炎患者和家庭产生重大影响,加上历史上缺乏研究,阻碍了做出明智的计划生育决定的能力。目的:为了广泛推广我们在这一领域不断扩大的研究成果,我们举办了两次关于关节炎妊娠和育儿的公开网络研讨会,目的如下:1)为研究人员、患者和临床医生之间的讨论创造论坛;2)提高对未来需要研究的新问题的认识;3)为患者、护理人员和家属提供循证实用的建议。第一次关于妊娠和关节炎的网络研讨会联合了患者、临床医生和研究人员的观点。我们从不同背景的患者那里了解了关节炎怀孕的第一手挑战,包括那些强调长期医疗保健差距的患者。一位专门研究妊娠和生殖健康的风湿病学家分享了自己的见解,并以积极的前景总结说,围产期研究正在进行中,正在研究新兴的抗风湿病疗法。第二次关于养育和关节炎的网络研讨会讨论了基于证据的资源和策略来支持父母,整合了研究人员和临床医生的见解。结论:这些网络研讨会阐明了关节炎对患者和家庭的深远影响,并揭示了未来研究的知识空白。
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引用次数: 0
Proceedings from The Consortium for Technology & Innovation in Pediatrics (CTIP) 2024 Annual Pediatric Device Innovation Symposium. 来自儿科技术与创新联盟(CTIP) 2024年度儿科器械创新研讨会的会议记录。
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2025-03-24 DOI: 10.1186/s12919-025-00315-7
Tamara P Lambert, Grzegorz Zapotoczny, Bianca Riello, Nadine Afari, Yaniv Bar-Cohen, Madison Christmas, Salima Jamal, Shahida Qazi, Melissa A Bent, Juan Espinoza

On August 9, 2024, the CTIP symposium brought together various stakeholders in pediatric medical device (PMD) innovation to discuss the current state of pediatric medical devices (PMDs) and action steps that can collectively be taken to further drive PMD innovation. Meeting topics included 1) the Future of Pediatric Innovation, 2) Engaging Patients and Their Families in PMD Development, 3) Partnership Opportunities to Support PMD Research and Development (R&D), 4) Leveraging Real-World Evidence to Enhance PMDs, and 5) Fundraising and Investing in Pediatrics. This paper provides a comprehensive summary of the symposium proceedings, highlighting the critical needs, challenges, and opportunities in the PMD sector, and outlines potential areas for collaboration among stakeholders to drive progress in PMD development.

2024年8月9日,CTIP研讨会汇聚了儿科医疗器械(PMD)创新领域的各利益相关方,共同探讨儿科医疗器械(PMD)的现状以及为进一步推动儿科医疗器械创新而共同采取的行动步骤。会议主题包括:1)儿科创新的未来;2)让患者及其家属参与儿科医疗器械的开发;3)支持儿科医疗器械研发(R&D)的合作机会;4)利用现实世界的证据增强儿科医疗器械;5)儿科筹资和投资。本文对研讨会的讨论情况进行了全面总结,强调了儿科医疗领域的关键需求、挑战和机遇,并概述了利益相关者之间为推动儿科医疗发展而开展合作的潜在领域。
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引用次数: 0
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