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Social network analysis of COVID-19 vaccine YouTube videos in Odisha, India: mapping the channel network and analyzing comment sentiment. 印度奥迪沙COVID-19疫苗YouTube视频的社交网络分析:绘制频道网络图并分析评论情绪。
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2023-07-07 DOI: 10.1186/s12919-023-00260-3
Neil Alperstein, Paola Pascual-Ferrá, Rohini Ganjoo, Ananya Bhaktaram, Julia Burleson, Daniel J Barnett, Amelia M Jamison, Eleanor Kluegel, Satyanarayan Mohanty, Peter Z Orton, Manoj Parida, Sidharth Rath, Rajiv Rimal

India has reported more than 35 million confirmed cases of COVID-19 and nearly half a million cumulative deaths. Although vaccination rates for the first vaccine dose are quite high, one-third of the population has not received a second shot. Due to its widespread use and popularity, social media can play a vital role in enhancing vaccine acceptance. This study in a real-world setting utilizes YouTube videos in Odisha, India where the platform has deep penetration among the 18-35 target population, and secondarily their family and peers. Two contrasting videos were launched on the YouTube platform to examine how those videos operate within the broader recommender and subscription systems that determine the audience reach. Video analytics, algorithms for recommended videos, visual representation of connections created, centrality between the networks, and comment analysis was conducted. The results indicate that the video with a non-humorous tone and collectivistic appeal delivered by a female protagonist performed best with regard to views and time spent watching the videos. The results are of significance to health communicators who seek to better understand the platform mechanisms that determine the spread of videos and measures of viewer reactions based on viewer sentiment.

印度报告的 COVID-19 确诊病例已超过 3500 万例,累计死亡人数近 50 万。虽然第一剂疫苗的接种率相当高,但仍有三分之一的人口没有接种第二剂疫苗。由于社交媒体的广泛使用和普及,它可以在提高疫苗接受度方面发挥重要作用。本研究利用 YouTube 视频在印度奥迪沙邦的实际环境中进行了研究,该平台在 18-35 岁目标人群中的渗透率很高,其次是他们的家人和同龄人。我们在 YouTube 平台上发布了两个对比鲜明的视频,以研究这些视频如何在更广泛的推荐和订阅系统中运作,从而决定受众的覆盖范围。视频分析、推荐视频的算法、所创建连接的可视化表示、网络之间的中心性以及评论分析均已进行。结果表明,在观看次数和观看时间方面,由女主角传达的非幽默语气和集体主义诉求的视频表现最佳。这些结果对健康传播者来说意义重大,因为他们希望更好地了解决定视频传播的平台机制以及基于观众情绪的观众反应衡量标准。
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引用次数: 1
The evolution of COVID-19 vaccine hesitancy in Sub-Saharan Africa: evidence from panel survey data. 撒哈拉以南非洲地区对 COVID-19 疫苗犹豫不决的演变:来自面板调查数据的证据。
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2023-07-06 DOI: 10.1186/s12919-023-00266-x
Philip Wollburg, Yannick Markhof, Shelton Kanyanda, Alberto Zezza

Background: COVID-19 vaccination efforts are lagging in Sub-Saharan Africa, as just over 20 percent of the population has been fully vaccinated. COVID-19 vaccine hesitancy is considered important as a prerequisite for widespread vaccine take-up. Here, we study the dynamics of vaccine acceptance, its correlates, and reasons for hesitancy over time, drawing on two years of panel survey data.

Methods: In this observational study, we use multiple rounds of data from national High Frequency Phone Surveys (HFPS) in five countries in East and West Africa (Burkina Faso, Ethiopia, Malawi, Nigeria, and Uganda), covering a period between 2020 and 2022. The surveys are cross-country comparable and draw their samples from nationally representative sampling frames. Based on this data source, the study presents population-weighted means and performs multivariate regression analysis.

Results: COVID-19 vaccine acceptance was high throughout the study period (68% to 98%). However, acceptance levels were lower in 2022 than in 2020 in three countries (Burkina Faso, Malawi, Nigeria), and higher in one country (Uganda). Moreover, individuals are observed to change their stated vaccine attitudes between survey rounds, to a limited extent in some countries (Ethiopia) and more frequently in others (Burkina Faso, Malawi, Nigeria, Uganda). Vaccine hesitancy is higher in richer households, and those residing in urban areas; among women and those better educated. Hesitancy is lower in larger households and among heads of the household. The main reasons for hesitancy are concerns about side effects of the vaccine, its safety and efficacy, as well as assessments of COVID-19 risk, though these reasons fluctuate over time.

Conclusions: Reported COVID-19 vaccine acceptance levels remain far above vaccination rates in the study countries, suggesting that vaccine hesitancy is not the primary obstacle to reaching greater vaccine coverage, which may instead be related to access and delivery barriers as well as supply shortages. Nevertheless, vaccine attitudes appear malleable so that continued efforts are needed to retain high levels of vaccine acceptance.

背景:撒哈拉以南非洲地区的 COVID-19 疫苗接种工作进展缓慢,仅有 20% 多的人口接种了全部疫苗。COVID-19疫苗的犹豫不决被认为是广泛接种疫苗的重要先决条件。在此,我们利用两年的面板调查数据,研究疫苗接受度的动态变化、其相关因素以及犹豫不决的原因:在这项观察性研究中,我们使用了东非和西非五个国家(布基纳法索、埃塞俄比亚、马拉维、尼日利亚和乌干达)的多轮全国高频电话调查(HFPS)数据,时间跨度为 2020 年至 2022 年。这些调查具有跨国可比性,其样本来自具有全国代表性的抽样框架。基于这一数据来源,研究提出了人口加权平均值,并进行了多变量回归分析:结果:在整个研究期间,COVID-19 疫苗的接受度都很高(68% 至 98%)。然而,在三个国家(布基纳法索、马拉维和尼日利亚),2022 年的接受度低于 2020 年,而在一个国家(乌干达)则高于 2020 年。此外,据观察,在不同轮次的调查中,个人对疫苗的态度会发生变化,在一些国家(埃塞俄比亚)变化程度有限,而在另一些国家(布基纳法索、马拉维、尼日利亚、乌干达)则更为频繁。在较富裕的家庭、居住在城市地区的家庭、妇女和受教育程度较高的人群中,对疫苗犹豫不决的比例较高。人数较多的家庭和户主的犹豫程度较低。犹豫的主要原因是对疫苗副作用、安全性和有效性的担忧,以及对 COVID-19 风险的评估,尽管这些原因会随着时间的推移而波动:结论:研究国家报告的 COVID-19 疫苗接受水平仍远远高于疫苗接种率,这表明疫苗接种犹豫并不是实现更大疫苗覆盖率的主要障碍,相反,这可能与获取和接种障碍以及供应短缺有关。然而,疫苗态度似乎是可以改变的,因此需要继续努力以保持较高的疫苗接受率。
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引用次数: 3
Integrated analysis of online signals and insight generation about digital conversations on COVID-19 vaccines in Eastern and Southern Africa: a longitudinal analysis of social listening data. 对东部和南部非洲有关 COVID-19 疫苗的数字对话的在线信号和洞察力的综合分析:对社交聆听数据的纵向分析。
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2023-07-04 DOI: 10.1186/s12919-023-00261-2
Silvia Sommariva, Helena Ballester Bon, Sofia De Almeida, Jenna Mote, Sijmen Brouwers, Massimiliano Sani, Natalie Fol

Background: During the COVID-19 pandemic, social listening programs across digital channels have become an integral part of health preparedness and response planning, allowing to capture and address questions, information needs, and misinformation shared by users. This study identifies key social listening trends around COVID-19 vaccines in Eastern and Southern Africa and analyses how online conversations about this issue evolved over time.

Methods: A taxonomy developed and refined in collaboration with social and behaviour change teams was used to filter online conversations into nine subtopic categories. The taxonomy was applied to online content tracked in 21 countries in Eastern and Southern Africa over the period December 1, 2020-December 31, 2021. Metrics captured included volume of posts or articles and related user engagement. Qualitative analysis of content was conducted to identify key concerns, information voids and misinformation.

Results: Over 300,000 articles and posts about COVID-19 vaccines shared by users or outlets geolocated in the region were analysed. These results generated over 14 million engagements on social media and digital platforms. The analysis shows how conversations about access and availability of vaccines represented the largest share of engagement over the course of the period. Conversations about vaccine effectiveness and safety represented the second and third largest share of engagement, with peaks observed in August and November 2021. Online interest in childhood vaccination increased over time as vaccine eligibility criteria expanded in some countries in the region. Conversations mentioning mandates and certificates peaked in the last quarter of 2021, as governments as private sector entities expanded vaccine requirements.

Conclusions: Findings from this study show the importance of monitoring conversation trends over time and adjust social listening data collection systems to include emerging topics. The study also points to the need to consider concerns, information voids and misinformation around effectiveness and safety of vaccines in the context of overall concern for vaccine availability and access in Eastern and Southern Africa. This is fundamental to inform social and behaviour change strategies that promote vaccine demand effectively, without increasing public frustration over vaccine availability challenges and downplaying concerns around vaccine equity.

背景:在 COVID-19 大流行期间,数字渠道上的社交聆听计划已成为卫生准备和响应计划中不可或缺的一部分,可以捕捉并解决用户分享的问题、信息需求和错误信息。本研究确定了东部和南部非洲围绕 COVID-19 疫苗的主要社交聆听趋势,并分析了有关这一问题的在线对话是如何随着时间的推移而演变的:与社会和行为改变团队合作开发并完善的分类法用于将在线对话筛选为九个子主题类别。该分类法适用于 2020 年 12 月 1 日至 2021 年 12 月 31 日期间在东部和南部非洲 21 个国家跟踪的在线内容。采集的指标包括帖子或文章的数量以及相关的用户参与度。对内容进行了定性分析,以确定关键问题、信息空白和错误信息:结果:分析了该地区用户或媒体分享的有关 COVID-19 疫苗的 30 多万篇文章和帖子。这些结果在社交媒体和数字平台上产生了超过 1400 万次参与。分析结果表明,在此期间,关于疫苗的可及性和可用性的对话所占的参与比例最大。关于疫苗有效性和安全性的对话占参与量的第二和第三位,高峰期出现在 2021 年 8 月和 11 月。随着该地区一些国家疫苗接种资格标准的扩大,网上对儿童疫苗接种的兴趣也随之增加。在 2021 年最后一个季度,随着政府和私营部门实体扩大疫苗接种要求,提及任务和证书的对话达到高峰:本研究的结果表明,监测一段时间内的对话趋势和调整社交聆听数据收集系统以纳入新出现的话题非常重要。研究还指出,在东部和南部非洲对疫苗可用性和可及性的整体关注背景下,有必要考虑围绕疫苗有效性和安全性的担忧、信息空白和错误信息。这对于制定有效促进疫苗需求的社会和行为改变战略至关重要,同时又不会增加公众对疫苗供应挑战的挫败感和淡化对疫苗公平性的担忧。
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引用次数: 1
Using community theater to improve demand for vaccination services in the Niger Delta Region of Nigeria. 利用社区剧场提高尼日利亚尼日尔三角洲地区对疫苗接种服务的需求。
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2023-07-03 DOI: 10.1186/s12919-023-00263-0
Chijioke Chikere Kaduru, Geraldine Chinonso Mbagwu, Dumale Koko Aadum, Ganiyat Eshikhena, Godwin Anusa Idim, Uche Francis Ibe, Timiebiere Sabenus, Fofah Gawain Jenson, Edmund Egbe, Neni Aworabhi-Oki, Happiness Masa, Martins Bekesu, Abisoye Sunday Oyeyemi

Introduction: Despite abundant evidence showing immunization as a lifesaving public health measure, a large proportion of Nigerian children are still not or fully vaccinated. Lack of awareness and distrust of the immunization process by caregivers are some of the reasons for poor immunization coverage which need to be addressed. This study aimed at improving vaccination demand, acceptance and uptake in Bayelsa and Rivers State, both in the Niger Delta Region (NDR) of Nigeria through a human-centered process of trust building, education and social support.

Methods: A quasi-experimental intervention christened Community Theater for Immunization (CT4I) was deployed in 18 selected communities between November 2019 and May 2021 in the two states. In the intervention localities, relevant stakeholders including the leadership of the health system, community leaders, health workers and community members were engaged and actively involved in the design and performance of the theaters. The content for the theater showcased real stories, using a human-centered design (HCD) of ideation, co-creation, rapid prototyping, feedback collection and iteration. Pre- and post-intervention data on the demand and utilization of vaccination services were collected using a mixed method.

Results: In the two states, 56 immunization managers and 59 traditional and religious leaders were engaged. Four broad themes implicating user and provider factors emerged from the 18 focus group discussions as responsible for low immunization uptake in the communities. Of the 217 caregivers trained on routine immunization and theater performances, 72% demonstrated a knowledge increase at the post-test. A total of 29 performances attended by 2,258 women were staged with 84.2% of the attendees feeling satisfied. At the performances, 270 children received vaccine shots (23% were zero-dose). There was a 38% increase in the proportion of fully immunized children in the communities and 9% decline in the proportion of zero-dose children from baseline.

Conclusion: Both demand- and supply-side factors were identified as responsible for poor vaccination in the intervention communities. Our intervention demonstrates that caregivers will demand immunization services if they are engaged through community theater using a human-centered design (HCD). We recommend a scaling up of HCD to address the challenge of vaccine hesitancy.

导言:尽管有大量证据表明免疫接种是一项挽救生命的公共卫生措施,但尼日利亚仍有很大一部分儿童没有接种或没有完全接种疫苗。护理人员对免疫接种过程缺乏认识和不信任是免疫接种覆盖率低的部分原因,需要加以解决。本研究旨在通过以人为本的信任建设、教育和社会支持过程,提高尼日利亚尼日尔三角洲地区(NDR)巴耶尔萨州和河流州的疫苗接种需求、接受度和接种率:方法:2019 年 11 月至 2021 年 5 月期间,在这两个州的 18 个选定社区部署了一项名为 "社区免疫剧场"(CT4I)的准实验性干预措施。在干预地区,包括卫生系统领导、社区领袖、卫生工作者和社区成员在内的相关利益攸关方参与并积极参与了剧场的设计和演出。剧场的内容展示了真实的故事,采用了以人为本的设计(HCD),包括构思、共同创作、快速原型设计、反馈收集和迭代。采用混合方法收集了关于疫苗接种服务需求和利用情况的干预前和干预后数据:结果:在这两个州,56 名免疫接种管理人员和 59 名传统和宗教领袖参与其中。在 18 次焦点小组讨论中,有四个主题涉及用户和提供者的因素,这些因素是造成社区免疫接种率低的原因。在接受常规免疫接种和戏剧表演培训的 217 名护理人员中,72% 的人在后期测试中表现出知识增长。共有 2 258 名妇女观看了 29 场演出,84.2% 的观众表示满意。在演出中,270 名儿童接种了疫苗(23% 为零剂量)。与基线相比,社区中完全接种疫苗的儿童比例增加了 38%,零剂量儿童比例下降了 9%:结论:需求方和供应方因素都是造成干预社区疫苗接种率低的原因。我们的干预措施表明,如果采用以人为本的设计(HCD),通过社区剧场让护理人员参与进来,他们就会要求获得免疫接种服务。我们建议扩大人本设计的规模,以应对疫苗接种犹豫不决的挑战。
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引用次数: 0
Leading from the frontlines: community-oriented approaches for strengthening vaccine delivery and acceptance. 前线领导:以社区为导向的加强疫苗交付和接受的方法。
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2023-06-30 DOI: 10.1186/s12919-023-00259-w
Baldeep K Dhaliwal, Rajeev Seth, Betty Thankachen, Yawar Qaiyum, Svea Closser, Tyler Best, Anita Shet

Background: Although immunization is one of the most successful public health interventions, vaccine hesitancy and the COVID-19 pandemic have strained health systems, contributing to global reductions in immunization coverage. Existing literature suggests that involving community members in vaccine interventions has been beneficial, but efforts to facilitate community ownership to motivate vaccine acceptance have been limited.

Methods: Our research leveraged community-based participatory research to closely involve the community from conception to implementation of an intervention to facilitate vaccine acceptance in Mewat District in Haryana, an area in India with extremely low vaccination coverage. Through the development of a community accountability board, baseline data collection on vaccination barriers and facilitators, and two human-centered design workshops, our team co-created a six-pronged intervention with community leaders and community health workers. This intervention included involving religious leaders in vaccine discussions, creating pamphlets of local vaccine champions for dissemination to parent and child caregivers, creating short videos of local leaders advocating for vaccines, implementing communication training exercises for community health workers, and implementing strategies to strengthen coordination between health workers and supervisors.

Results: Post-intervention data suggested parents and child caregivers had improvements in knowledge of the purpose of vaccines and side effects of vaccines. They noted that the involvement of religious leaders was beneficial, they were more willing to travel to vaccinate their children, and they had fewer non-logistical reasons to refuse vaccination services. Interviews with community leaders and community health workers who were involved in the creation of the intervention suggested that they experienced higher levels of ownership, they were better equipped to address community concerns, and that vaccine misinformation decreased in the post-intervention period.

Conclusion: Through this unique intervention to strengthen vaccine uptake that incorporated the needs, interests, and expertise of local community members, we developed a community-driven approach to strengthen vaccine acceptance in a population with low uptake. This comprehensive approach is essential to amplify local voices, identify local concerns and advocates, and leverage bottom-up strategies to co-design successful interventions to facilitate long-term change.

背景:尽管免疫接种是最成功的公共卫生干预措施之一,但疫苗接种犹豫不决和 COVID-19 大流行给卫生系统造成了压力,导致全球免疫接种覆盖率下降。现有文献表明,让社区成员参与疫苗干预是有益的,但促进社区自主权以推动疫苗接受度的努力却很有限:我们的研究利用基于社区的参与式研究,让社区密切参与一项干预措施从构思到实施的全过程,以促进哈里亚纳邦梅瓦特区对疫苗的接受,该地区是印度疫苗接种覆盖率极低的地区。通过建立社区责任委员会、收集有关疫苗接种障碍和促进因素的基线数据以及举办两次以人为本的设计研讨会,我们的团队与社区领袖和社区卫生工作者共同制定了一项六管齐下的干预措施。干预措施包括让宗教领袖参与疫苗讨论、制作当地疫苗倡导者的小册子分发给家长和儿童看护人、制作当地领袖倡导疫苗的视频短片、为社区卫生工作者开展沟通培训活动,以及实施加强卫生工作者与主管之间协调的策略:干预后的数据表明,家长和儿童看护者对疫苗目的和副作用的了解有所提高。他们指出,宗教领袖的参与是有益的,他们更愿意出远门为孩子接种疫苗,而且他们拒绝接受疫苗接种服务的非逻辑原因也减少了。对参与制定干预措施的社区领袖和社区卫生工作者的访谈表明,他们体验到了更高的主人翁精神,他们更有能力解决社区关注的问题,疫苗误导在干预后也有所减少:通过这种结合当地社区成员的需求、兴趣和专业知识的独特干预措施,我们开发出了一种以社区为主导的方法来提高疫苗在低接种率人群中的接受度。这种综合方法对于扩大当地声音、确定当地关注的问题和倡导者、利用自下而上的策略共同设计成功的干预措施以促进长期变化至关重要。
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引用次数: 0
Harnessing a decade of research at the Research Institute for Bioscience and Biotechnology in Kathmandu, Nepal: Proceedings of the Fourth International Conference ICBB-2022. 利用尼泊尔加德满都生物科学和生物技术研究所的十年研究成果:第四届 ICBB-2022 国际会议论文集。
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2023-06-02 DOI: 10.1186/s12919-023-00252-3
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引用次数: 0
Meeting Abstracts from the 8th Annual Atlantic Corridor Medical Student Research Conference. 第八届大西洋走廊医学院学生研究年会会议摘要。
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2023-05-18 DOI: 10.1186/s12919-023-00253-2
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引用次数: 0
Abstracts from the 6th International Symposium of Advanced Topics in Exercise Physiology: Interval training as an efficient strategy to overcome the XXI century diseases with emphasis in the mental brain diseases : Ensenada Baja California, México. 27-28 October 2022 (virtual symposium). 第六届运动生理学高级专题国际研讨会:间歇训练是克服21世纪疾病的有效策略,重点是精神脑疾病:Ensenada Baja California, msamuxico。2022年10月27-28日(虚拟研讨会)。
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2023-03-02 DOI: 10.1186/s12919-023-00251-4
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引用次数: 0
Conference Proceedings - 6th International Conference on Molecular Diagnostics and Biomarker Discovery (MDBD 2022): Building Resilience in Biomedical Research : Penang, Malaysia. 11-13 October 2022. 会议记录-第六届分子诊断和生物标志物发现国际会议(MDBD 2022):在生物医学研究中建立弹性:槟城,马来西亚,2022年10月11日至13日。
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2022-12-21 DOI: 10.1186/s12919-022-00237-8
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引用次数: 1
Abstracts from the 11th International Conference for Healthcare and Medical Students (ICHAMS) 第11届国际医疗保健与医学学生会议(ICHAMS)摘要
Q2 Biochemistry, Genetics and Molecular Biology Pub Date : 2022-10-01 DOI: 10.1186/s12919-022-00236-9
I. Rezus, Vasile-Claudiu Mihai, E. Rezus, Taibah H Aladraj, Ahmed S. Keshta, Anas A. Zeidan, Mohammad A Abousaleh, Nitya Kumar, I. Mukhtar, Gabrielle E. Sanatani, Sonia Franciosi, J. Bone, B. Dechert, Kevin Harris, M. Sadarangani
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引用次数: 0
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