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Call for the responsible artificial intelligence in the healthcare. 呼吁在医疗保健领域使用负责任的人工智能。
IF 4.1 Q2 Computer Science Pub Date : 2023-12-21 DOI: 10.1136/bmjhci-2023-100920
Umashankar Upadhyay, Anton Gradisek, Usman Iqbal, Eshita Dhar, Yu-Chuan Li, Shabbir Syed-Abdul

The integration of artificial intelligence (AI) into healthcare is progressively becoming pivotal, especially with its potential to enhance patient care and operational workflows. This paper navigates through the complexities and potentials of AI in healthcare, emphasising the necessity of explainability, trustworthiness, usability, transparency and fairness in developing and implementing AI models. It underscores the 'black box' challenge, highlighting the gap between algorithmic outputs and human interpretability, and articulates the pivotal role of explainable AI in enhancing the transparency and accountability of AI applications in healthcare. The discourse extends to ethical considerations, exploring the potential biases and ethical dilemmas that may arise in AI application, with a keen focus on ensuring equitable and ethical AI use across diverse global regions. Furthermore, the paper explores the concept of responsible AI in healthcare, advocating for a balanced approach that leverages AI's capabilities for enhanced healthcare delivery and ensures ethical, transparent and accountable use of technology, particularly in clinical decision-making and patient care.

人工智能(AI)与医疗保健的结合正逐渐变得举足轻重,尤其是其在加强患者护理和业务工作流程方面的潜力。本文探讨了人工智能在医疗保健领域的复杂性和潜力,强调了在开发和实施人工智能模型过程中可解释性、可信性、可用性、透明度和公平性的必要性。它强调了 "黑箱 "挑战,突出了算法输出与人类可解释性之间的差距,并阐明了可解释的人工智能在提高医疗保健领域人工智能应用的透明度和问责制方面的关键作用。论述延伸到伦理方面的考虑,探讨了人工智能应用中可能出现的潜在偏见和伦理困境,重点关注如何确保在全球不同地区公平、合乎伦理地使用人工智能。此外,本文还探讨了负责任的人工智能在医疗保健中的应用这一概念,主张采用一种平衡的方法,利用人工智能的能力来加强医疗保健服务,并确保技术的使用,尤其是在临床决策和患者护理方面的使用,做到合乎道德、透明和负责任。
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引用次数: 0
Call to digital health leaders: test and leverage this guideline to support health information technology implementation in practice. 呼吁数字卫生领导者:测试和利用本指南,以支持卫生信息技术在实践中的实施。
IF 4.1 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2023-12-02 DOI: 10.1136/bmjhci-2023-100829
Samantha Erin Harding, Karen Day, Peter Carswell

Background: Health information technology (HIT) is increasingly used to enable health service/system transformation. Most HIT implementations fail to some degree; very few demonstrate sustainable success. No guidelines exist for health service leaders to leverage factors associated with success. The purpose of this paper is to present an evidence-based guideline for leaders to test and leverage in practice.

Methods: This guideline was developed from a literature review and refined by a set of eight interviews with people in senior HIT roles, which were thematically analysed. It was refined in the consultancy work of the first author and confirmed after minor refinements.

Results: Five key actions were identified: relationships, vision, HIT system attributes, constant evaluation and learning culture.

Conclusions: This guideline presents a significant opportunity for health system leaders to systematically check relevant success factors during the implementation process of single projects and regional/national programmes.

背景:卫生信息技术(HIT)越来越多地用于实现卫生服务/系统转型。大多数HIT实现在某种程度上都失败了;很少有持续的成功。目前还没有指导卫生服务领导者如何利用与成功相关的因素。本文的目的是为领导者在实践中测试和利用提供一个基于证据的指导方针。方法:本指南从文献综述中发展而来,并通过对HIT高级角色的八组访谈进行了改进,并对其进行了主题分析。这是在第一作者的咨询工作中完善的,经过小的修改后得到了确认。结果:确定了五个关键行动:关系、愿景、HIT系统属性、持续评估和学习文化。结论:本指南为卫生系统领导人在单个项目和区域/国家规划实施过程中系统检查相关成功因素提供了重要机会。
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引用次数: 0
ChatGPT in Iranian medical licensing examination: evaluating the diagnostic accuracy and decision-making capabilities of an AI-based model 伊朗医学执照考试中的 ChatGPT:评估基于人工智能模型的诊断准确性和决策能力
IF 4.1 Q2 Computer Science Pub Date : 2023-12-01 DOI: 10.1136/bmjhci-2023-100815
Manoochehr Ebrahimian, Behdad Behnam, Negin Ghayebi, Elham Sobhrakhshankhah
Introduction Large language models such as ChatGPT have gained popularity for their ability to generate comprehensive responses to human queries. In the field of medicine, ChatGPT has shown promise in applications ranging from diagnostics to decision-making. However, its performance in medical examinations and its comparison to random guessing have not been extensively studied. Methods This study aimed to evaluate the performance of ChatGPT in the preinternship examination, a comprehensive medical assessment for students in Iran. The examination consisted of 200 multiple-choice questions categorised into basic science evaluation, diagnosis and decision-making. GPT-4 was used, and the questions were translated to English. A statistical analysis was conducted to assess the performance of ChatGPT and also compare it with a random test group. Results The results showed that ChatGPT performed exceptionally well, with 68.5% of the questions answered correctly, significantly surpassing the pass mark of 45%. It exhibited superior performance in decision-making and successfully passed all specialties. Comparing ChatGPT to the random test group, ChatGPT’s performance was significantly higher, demonstrating its ability to provide more accurate responses and reasoning. Conclusion This study highlights the potential of ChatGPT in medical licensing examinations and its advantage over random guessing. However, it is important to note that ChatGPT still falls short of human physicians in terms of diagnostic accuracy and decision-making capabilities. Caution should be exercised when using ChatGPT, and its results should be verified by human experts to ensure patient safety and avoid potential errors in the medical field. Data are available on reasonable request.
引言 大型语言模型(如 ChatGPT)因其能够生成对人类查询的全面回复而广受欢迎。在医学领域,从诊断到决策,ChatGPT 都显示出良好的应用前景。然而,它在医学检查中的表现以及与随机猜测的比较尚未得到广泛研究。方法 本研究旨在评估 ChatGPT 在实习前考试中的表现,这是一项针对伊朗学生的综合医学评估。考试包括 200 道选择题,分为基础科学评估、诊断和决策。使用的是 GPT-4,试题被翻译成英语。为了评估 ChatGPT 的性能,并将其与随机测试组进行比较,我们进行了统计分析。结果 结果显示,ChatGPT 的表现非常出色,68.5% 的问题回答正确,大大超过了 45% 的及格线。它在决策方面表现出色,并成功通过了所有专业测试。将 ChatGPT 与随机测试组相比,ChatGPT 的成绩明显更高,这表明它有能力提供更准确的回答和推理。结论 本研究凸显了 ChatGPT 在医学执业资格考试中的潜力及其相对于随机猜测的优势。不过,需要注意的是,就诊断准确性和决策能力而言,ChatGPT 仍与人类医生存在差距。使用 ChatGPT 时应谨慎,其结果应由人类专家验证,以确保患者安全,避免医疗领域潜在的错误。如有合理要求,可提供相关数据。
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引用次数: 0
Exploring the reliability of inpatient EMR algorithms for diabetes identification 探索住院病人 EMR 算法在糖尿病识别方面的可靠性
IF 4.1 Q2 Computer Science Pub Date : 2023-12-01 DOI: 10.1136/bmjhci-2023-100894
Seungwon Lee, Elliot A Martin, Jie Pan, Cathy A Eastwood, Danielle A Southern, David J T Campbell, Abdel Aziz Shaheen, Hude Quan, Sonia Butalia
Introduction Accurate identification of medical conditions within a real-time inpatient setting is crucial for health systems. Current inpatient comorbidity algorithms rely on integrating various sources of administrative data, but at times, there is a considerable lag in obtaining and linking these data. Our study objective was to develop electronic medical records (EMR) data-based inpatient diabetes phenotyping algorithms. Materials and methods A chart review on 3040 individuals was completed, and 583 had diabetes. We linked EMR data on these individuals to the International Classification of Disease (ICD) administrative databases. The following EMR-data-based diabetes algorithms were developed: (1) laboratory data, (2) medication data, (3) laboratory and medications data, (4) diabetes concept keywords and (5) diabetes free-text algorithm. Combined algorithms used or statements between the above algorithms. Algorithm performances were measured using chart review as a gold standard. We determined the best-performing algorithm as the one that showed the high performance of sensitivity (SN), and positive predictive value (PPV). Results The algorithms tested generally performed well: ICD-coded data, SN 0.84, specificity (SP) 0.98, PPV 0.93 and negative predictive value (NPV) 0.96; medication and laboratory algorithm, SN 0.90, SP 0.95, PPV 0.80 and NPV 0.97; all document types algorithm, SN 0.95, SP 0.98, PPV 0.94 and NPV 0.99. Discussion Free-text data-based diabetes algorithm can yield comparable or superior performance to a commonly used ICD-coded algorithm and could supplement existing methods. These types of inpatient EMR-based algorithms for case identification may become a key method for timely resource planning and care delivery. Data may be obtained from a third party and are not publicly available. Restrictions apply to the availability of these data. Data were obtained from Alberta Health Services and are available with the permission of Alberta Health Services.
导言 在实时住院环境中准确识别医疗状况对医疗系统至关重要。目前的住院病人合并症算法依赖于整合各种来源的管理数据,但有时在获取和连接这些数据方面存在相当大的滞后性。我们的研究目标是开发基于电子病历(EMR)数据的住院病人糖尿病表型算法。材料和方法 完成了对 3040 人的病历审查,其中 583 人患有糖尿病。我们将这些患者的电子病历数据与国际疾病分类(ICD)管理数据库进行了链接。我们开发了以下基于 EMR 数据的糖尿病算法:(1) 实验室数据;(2) 药物数据;(3) 实验室和药物数据;(4) 糖尿病概念关键词;(5) 糖尿病自由文本算法。使用的组合算法或上述算法之间的语句。使用病历审查作为金标准来衡量算法性能。我们将灵敏度(SN)和阳性预测值(PPV)表现较高的算法确定为表现最佳的算法。结果 测试的算法普遍表现良好:ICD编码数据,SN为0.84,特异性(SP)为0.98,PPV为0.93,阴性预测值(NPV)为0.96;药物和实验室算法,SN为0.90,SP为0.95,PPV为0.80,NPV为0.97;所有文件类型算法,SN为0.95,SP为0.98,PPV为0.94,NPV为0.99。讨论 基于自由文本数据的糖尿病算法可产生与常用的 ICD 编码算法相当或更高的性能,可作为现有方法的补充。这类基于住院病人 EMR 的病例识别算法可能成为及时规划资源和提供护理的关键方法。数据可能来自第三方,不对外公开。这些数据的可用性受到限制。数据来自艾伯塔省卫生服务机构,经艾伯塔省卫生服务机构许可后提供。
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引用次数: 0
Electronic health record intervention to increase use of NSAIDs as analgesia for hospitalised patients: a cluster randomised controlled study 电子健康记录干预增加住院病人使用非甾体抗炎药镇痛:分组随机对照研究
IF 4.1 Q2 Computer Science Pub Date : 2023-12-01 DOI: 10.1136/bmjhci-2023-100842
Tasce Bongiovanni, Mark J Pletcher, Andrew Robinson, Elizabeth Lancaster, Li Zhang, Matthias Behrends, Elizabeth Wick, Andrew Auerbach
Background Prescribing non-opioid pain medications, such as non-steroidal anti-inflammatory (NSAIDs) medications, has been shown to reduce pain and decrease opioid use, but it is unclear how to effectively encourage multimodal pain medication prescribing for hospitalised patients. Therefore, the aim of this study is to evaluate the effect of prechecking non-opioid pain medication orders on clinician prescribing of NSAIDs among hospitalised adults. Methods This was a cluster randomised controlled trial of adult (≥18 years) hospitalised patients admitted to three hospital sites under one quaternary hospital system in the USA from 2 March 2022 to 3 March 2023. A multimodal pain order panel was embedded in the admission order set, with NSAIDs prechecked in the intervention group. The intervention group could uncheck the NSAID order. The control group had access to the same NSAID order. The primary outcome was an increase in NSAID ordering. Secondary outcomes include NSAID administration, inpatient pain scores and opioid use and prescribing and relevant clinical harms including acute kidney injury, new gastrointestinal bleed and in-hospital death. Results Overall, 1049 clinicians were randomised. The study included 6239 patients for a total of 9595 encounters. Both NSAID ordering (36 vs 43%, p<0.001) and administering (30 vs 34%, p=0.001) by the end of the first full hospital day were higher in the intervention (prechecked) group. There was no statistically significant difference in opioid outcomes during the hospitalisation and at discharge. There was a statistically but perhaps not clinically significant difference in pain scores during both the first and last full hospital day. Conclusions This cluster randomised controlled trial showed that prechecking an order for NSAIDs to promote multimodal pain management in the admission order set increased NSAID ordering and administration, although there were no changes to pain scores or opioid use. While prechecking orders is an important way to increase adoption, safety checks should be in place. Data are available in a public, open access repository. Data is publicly available from the Centers of Medicare and Medicaid Services from the US Government.
背景开具非阿片类止痛药(如非甾体类抗炎药)已被证明可以减轻疼痛并减少阿片类药物的使用,但如何有效鼓励为住院患者开具多模式止痛药尚不清楚。因此,本研究旨在评估预先检查非阿片类止痛药医嘱对临床医生为住院成年人开具非甾体抗炎药处方的影响。方法 这是一项分组随机对照试验,研究对象是 2022 年 3 月 2 日至 2023 年 3 月 3 日期间在美国一家四级医院系统下的三家医院住院的成人(≥18 岁)住院患者。入院医嘱中嵌入了一个多模式疼痛医嘱面板,干预组预先勾选了非甾体抗炎药。干预组可以取消对非甾体抗炎药单的勾选。对照组可使用相同的非甾体抗炎药单。主要结果是增加了非甾体抗炎药的订购量。次要结果包括非甾体抗炎药的使用、住院患者疼痛评分、阿片类药物的使用和处方,以及相关的临床危害,包括急性肾损伤、新发消化道出血和院内死亡。结果 共有 1049 名临床医生接受了随机治疗。研究共涉及 6239 名患者,共计 9595 次就诊。干预(预先检查)组的非甾体抗炎药订购率(36% 对 43%,P<0.001)和住院第一天结束时的用药率(30% 对 34%,P=0.001)均高于干预(预先检查)组。住院期间和出院时的阿片类药物治疗效果在统计学上没有明显差异。住院第一天和最后一天的疼痛评分在统计学上有显著差异,但临床意义不大。结论 这项分组随机对照试验表明,在入院医嘱中预先核对非甾体抗炎药的医嘱以促进多模式疼痛管理,可以增加非甾体抗炎药的医嘱和用药量,但疼痛评分或阿片类药物的使用没有变化。虽然预先检查医嘱是提高采用率的重要方法,但安全检查也应到位。数据可在公开、开放的资料库中获取。数据由美国政府医疗保险和医疗补助服务中心公开提供。
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引用次数: 0
Electronic health card: a technological solution to promote the Chinese integrated healthcare system in the digital age 电子健康卡:数字时代促进中国整合医疗系统的技术解决方案
IF 4.1 Q2 Computer Science Pub Date : 2023-12-01 DOI: 10.1136/bmjhci-2023-100911
Wenjuan Tao, Tao Gu, Yujue Li, Weimin Li
People-centred integrated care, with an emphasis on ensuring healthcare services are well coordinated around people’s needs,[1][1] is regarded as a global strategy towards universal health coverage.[2][2] Underutilisation of information technology and lack of interoperability are identified as the
以人为本的综合护理强调确保医疗保健服务围绕人们的需求得到良好的协调,[1][1] 被视为实现全民健康覆盖的全球战略[2][2] 。
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引用次数: 0
Role of evaluation throughout the life cycle of biomedical and health AI applications 评估在生物医学和健康人工智能应用整个生命周期中的作用
IF 4.1 Q2 Computer Science Pub Date : 2023-12-01 DOI: 10.1136/bmjhci-2023-100925
Edward H Shortliffe
In the development and evaluation of medical artificial intelligence (AI) programmes, there is a tendency to focus the work on the system’s decision-making performance. This is natural, since the typical goal is to develop software that can assist physicians or other clinicians with decision tasks
在开发和评估医疗人工智能(AI)程序时,人们倾向于将工作重点放在系统的决策性能上。这很自然,因为开发软件的典型目标是协助医生或其他临床医师完成决策任务
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引用次数: 0
Cognitive science in the evaluation of medical AI systems 认知科学在医疗人工智能系统评估中的应用
IF 4.1 Q2 Computer Science Pub Date : 2023-12-01 DOI: 10.1136/bmjhci-2023-100929
Vimla Lodhia Patel
Clinical cognition is central to a clinician’s daily tasks, such as making diagnostic and therapeutic decisions. For example, doctors rely on their memory to recall relevant facts, concepts and experiences that can help them diagnose and treat their patients. Memory is needed for clinicians to
临床认知是临床医生日常工作的核心,例如做出诊断和治疗决定。例如,医生依靠记忆来回忆相关事实、概念和经验,从而帮助他们诊断和治疗病人。临床医生需要记忆力来
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引用次数: 0
Quantifying digital health inequality across a national healthcare system. 量化全国医疗保健系统中的数字健康不平等。
IF 4.1 Q2 Computer Science Pub Date : 2023-11-24 DOI: 10.1136/bmjhci-2023-100809
Joe Zhang, Jack Gallifant, Robin L Pierce, Aoife Fordham, James Teo, Leo Celi, Hutan Ashrafian

Objectives: Digital health inequality, observed as differential utilisation of digital tools between population groups, has not previously been quantified in the National Health Service (NHS). Deployment of universal digital health interventions, including a national smartphone app and online primary care services, allows measurement of digital inequality across a nation. We aimed to measure population factors associated with digital utilisation across 6356 primary care providers serving the population of England.

Methods: We used multivariable regression to test association of population and provider characteristics (including patient demographics, socioeconomic deprivation, disease burden, prescribing burden, geography and healthcare provider resource) with activation of two independent digital services during 2021/2022.

Results: We find a significant adjusted association between increased population deprivation and reduced digital utilisation across both interventions. Multivariable regression coefficients for most deprived quintiles correspond to 4.27 million patients across England where deprivation is associated with non-activation of the NHS App.

Conclusion: Results are concerning for technologically driven widening of healthcare inequalities. Targeted incentive to digital is necessary to prevent digital disparity from becoming health outcomes disparity.

目标:数字健康不平等,被观察为不同人群对数字工具的不同利用,以前在国家卫生服务(NHS)中没有被量化。部署普遍的数字卫生干预措施,包括全国智能手机应用程序和在线初级保健服务,可以衡量全国范围内的数字不平等。我们的目标是测量与6356名初级保健提供者为英格兰人口服务的数字利用相关的人口因素。方法:我们使用多变量回归来检验2021/2022年期间人口和提供者特征(包括患者人口统计学、社会经济剥夺、疾病负担、处方负担、地理和医疗保健提供者资源)与两个独立数字服务的激活之间的关联。结果:我们发现在两种干预措施中,人口剥夺增加和数字利用减少之间存在显著的调整关联。大多数贫困五分之一的多变量回归系数对应于整个英格兰的427万患者,其中剥夺与未激活NHS应用程序有关。结论:结果涉及技术驱动的医疗不平等扩大。有针对性的数字激励是必要的,以防止数字差距成为健康结果的差距。
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引用次数: 0
Proof-of-concept solution to create an interoperable timeline of healthcare data. 概念验证解决方案,用于创建可互操作的医疗保健数据时间表。
IF 4.1 Q2 Computer Science Pub Date : 2023-11-01 DOI: 10.1136/bmjhci-2023-100754
Sapna Trivedi, Stephen Hall, Fiona Inglis, Afzal Chaudhry

Objectives: To overcome the barriers of interoperability by sharing simulated patient data from different electronic health records systems and presenting them in an intuitive timeline of events.

Methods: The 'Patient Story' software comprising database and blockchain, PS Timeline Windows interface, PS Timeline Web interface and network relays on Azure cloud was customised for Epic and Lorenzo electonic patient record (EPR) systems used at different hospitals, using site-specific adapters.

Results: Each site could view their own clinical documents and view each other's site specific, fully coded test sets of (Care Connect) medications, conditions and allergies, in an aggregated single view.

Discussion: This work has shown that clinical data from different EPR systems can be successfully integrated and visualised on a single timeline, accessible by clinicians and patients.

Conclusion: The Patient Story system combined the timeline visualisation with successful interoperability across healthcare settings, as well giving patients the ability to directly interact with their timeline.

目标:通过共享来自不同电子健康记录系统的模拟患者数据并将其呈现在直观的事件时间表中,克服互操作性障碍。方法:“患者故事”软件包括数据库和区块链、PS Timeline Windows界面、PS Timeliner Web界面和Azure云上的网络中继,是为不同医院使用的Epic和Lorenzo电子病历(EPR)系统定制的,使用特定站点的适配器。结果:每个网站都可以查看自己的临床文档,并在一个汇总的单一视图中查看彼此网站特定的、完整编码的(Care Connect)药物、病情和过敏测试集。讨论:这项工作表明,来自不同EPR系统的临床数据可以在一个时间线上成功集成和可视化,临床医生和患者都可以访问。结论:患者故事系统将时间线可视化与医疗环境中的成功互操作性相结合,并使患者能够直接与时间线互动。
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引用次数: 0
期刊
BMJ Health & Care Informatics
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