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Antidiabetic and Hepatoprotective Activities of Bombax ceiba Young Roots in Alloxan-Induced Diabetic Mice 木棉幼根对四氧嘧啶诱导的糖尿病小鼠的抗糖尿病和保肝作用
Pub Date : 2018-08-31 DOI: 10.15226/JNHFS.2018.001140
A. H. M. Khurshid Alam, R. Sharmin, Maruf-ul- Islam, Md. Hasibul Hasan Joarder, Mohiuddin Mohammad Alamgir, M. Mostofa
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引用次数: 11
Calcium and Magnesium Levels Change in Relationship to Variations in Usual Dietary Nutrient Intake 钙和镁水平的变化与日常膳食营养摄入量的变化有关
Pub Date : 2018-08-31 DOI: 10.15226/JNHFS.2018.001142
R. Henkin
Objective: Changes in nutrient intake induce changes in calcium and magnesium metabolism. However, studies dealing with these changes were usually performed by addition of one specific nutrient to initiate changes in either calcium or magnesium in only one biological fluid, usually blood plasma or urine. We were interested in evaluating changes in both calcium and magnesium levels in several biological fluids simultaneously in relationship to usual intake of a wide range of dietary nutrients since this type of study has not been previously performed. Methods: Calcium and magnesium in blood plasma, urine and saliva and magnesium in erythrocytes were measured by flame aspiration atomic absorption spectrophotometry in 253 subjects, 150 women and 103 men in relationship to their usual dietary intake of calcium, magnesium, sodium, potassium, phosphorus, carbohydrate, fat, fiber, protein, vitamin D, vitamin C and total calories. Dietary nutrient intake was calculated by careful, systematic analysis of all food and fluids taken over three typical days by performance of computer based dietary analysis. Results: Complex changes occurred in calcium and magnesium levels in some but not all biological fluids as usual dietary nutrient intake varied. As sodium, potassium and total calorie intake increased urinary calcium excretion increased. As sodium, potassium, vitamin D and protein intake increased urinary magnesium excretion increased. As sodium intake increased salivary magnesium decreased. Conclusions: These studies demonstrate that calcium and magnesium levels in blood plasma, urine, saliva and nasal mucus are altered following variations in the usual intake of several dietary nutrients. These results can assist in forming a nutritional foundation upon which variations in the usual dietary intake of several nutrients alter calcium and magnesium levels in several biological fluids.
目的:营养摄入的变化引起钙和镁代谢的变化。然而,处理这些变化的研究通常是通过添加一种特定的营养素来启动一种生物流体(通常是血浆或尿液)中钙或镁的变化。我们感兴趣的是同时评估几种生物液中钙和镁水平的变化与通常摄入的广泛膳食营养素的关系,因为以前没有进行过这种类型的研究。方法:采用火焰原子吸收分光光度法测定253名受试者、150名女性和103名男性的血浆、尿液、唾液中的钙、镁和红细胞中的镁,并与他们日常饮食中钙、镁、钠、钾、磷、碳水化合物、脂肪、纤维、蛋白质、维生素D、维生素C和总热量的关系。通过基于计算机的饮食分析,对三天内摄入的所有食物和液体进行仔细、系统的分析,计算出膳食营养素摄入量。结果:一些但不是所有生物液中的钙和镁水平都发生了复杂的变化,因为通常的饮食营养摄入各不相同。随着钠、钾和总热量摄入的增加,尿钙排泄量增加。随着钠、钾、维生素D和蛋白质摄入量的增加,尿镁排泄量增加。随着钠摄入量的增加,唾液镁含量下降。结论:这些研究表明,血浆、尿液、唾液和鼻腔粘液中的钙和镁水平随着几种膳食营养素的正常摄入量的变化而改变。这些结果有助于形成一个营养基础,在此基础上,几种营养素的日常饮食摄入量的变化会改变几种生物液中的钙和镁水平。
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引用次数: 1
Dietary Magnesium Supplements – Is there any Problem? 膳食镁补充剂——有什么问题吗?
Pub Date : 2018-07-23 DOI: 10.15226/JNHFS.2018.001138
I. Télessy
Magnesium is essential to life, it’s out of question. But really do we need as much supplementation as we do today? Since magnesium-containing products are freely available as OTC drugs or dietary supplements, advertisment of such products got a huge accession. Dysmagnesemia may be a common problem and yet appropriate supplementation of magnesium is not as obvious as the insertions suggests it. We here present a review article addressing the theme.
镁对生命至关重要,这是毫无疑问的。但我们真的需要像今天这样多的补充吗?由于含镁产品可以作为非处方药或膳食补充剂免费获得,此类产品的广告获得了巨大的关注。镁缺乏症可能是一个常见的问题,但适当补充镁并不像插入物所表明的那样明显。
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引用次数: 4
Probiotic Therapy for Prevention of Necrotizing Enterocolitis in Preterm Infants – A Review 益生菌治疗预防早产儿坏死性小肠结肠炎的研究进展
Pub Date : 2018-06-29 DOI: 10.15226/jnhfs.2018.001137
S. Sarkar
Purpose: Preterm infants are prone to systemic infections due to increased intestinal permeability to potentially pathogens resulting from immature intestinal function, frequent use of broad-spectrum antibiotics, delay in initiating enteral feeding, infection control procedures and sterilization of milk. Very Low Birth Weight infants, particularly Extremely Low Birth Weight infants are at higher risk due to abnormal pattern of colonization, which may contribute to the pathogenesis of neonatal Necrotizing Enterocolitis (NEC). Dietary intervention through probiotic supplementation is widely adopted for the prophylaxis of NEC and nosocomial infections throughout the world. Design/Methodology/Approach: This review paper is based upon systematic review of randomized controlled trials, metaanalyses, research papers and books related to the short and longterm administration of single or mixed probiotic cultures for the prevention of NEC only in preterm infants. Clinical trials and cohort studies concerning manipulation of the intestinal microbiota in premature infants are also included. Evidence based data published in the English language retrieved from three databases Pub Med, Science Direct and Cochrane Reviews, published in The Cochrane Library from 2000-2016, using a combination of key words like necrotizing enterocolitis, probiotics and preterm infants have been considered. Findings: All probiotic strains are not equally efficacious for preventing NEC and application of probiotic combinations may be advantageous. Due to heterogeneity of probiotic formulations exclusive administration of probiotics in premature infants is not recommended and should be introduced along with breast milk as routine clinical practice for neonatal health care. Originality/Value: Probiotic foods have been found effective in modulating gastrointestinal flora to prevent NEC but safety aspects must be evaluated prior to consideration of probiotic therapy for preterm infants and neonates.
目的:由于肠道功能不成熟、频繁使用广谱抗生素、延迟开始肠内喂养、感染控制程序和牛奶灭菌导致肠道对潜在病原体的通透性增加,早产儿容易发生全身感染。极低出生体重婴儿,特别是极低出生重量婴儿,由于定植模式异常,其风险更高,这可能导致新生儿坏死性小肠结肠炎(NEC)的发病机制。通过补充益生菌进行饮食干预在世界各地被广泛用于预防NEC和医院感染。设计/方法/方法:这篇综述论文基于对随机对照试验、荟萃分析、研究论文和书籍的系统综述,这些试验和书籍与短期和长期使用单一或混合益生菌培养物预防早产儿NEC有关。还包括有关早产儿肠道微生物群操作的临床试验和队列研究。从Pub Med、Science Direct和Cochrane Reviews三个数据库中检索的以英语发表的循证数据已被考虑,这三个数据库于2000-2016年发表在the Cochrane Library上,使用了坏死性小肠结肠炎、益生菌和早产儿等关键词的组合。研究结果:并非所有益生菌菌株对预防NEC都同样有效,应用益生菌组合可能是有利的。由于益生菌配方的异质性,不建议早产儿单独服用益生菌,应将其与母乳一起作为新生儿保健的常规临床实践。独创性/价值:益生菌食品已被发现在调节胃肠道菌群以预防NEC方面有效,但在考虑对早产儿和新生儿进行益生菌治疗之前,必须评估安全性。
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引用次数: 0
Management of Food Allergens by Hospital Food Services in Barcelona City 巴塞罗那市医院食品服务部门对食品过敏原的管理
Pub Date : 2018-06-26 DOI: 10.15226/jnhfs.2018.001136
Laura Caballé Gavaldà, Mireia Fontcuberta, S. Portaña, G. Serral
In hospitals, food hygiene is considered an essential factor for preventing co-morbidity and reducing the length of the hospital stay, considering the vulnerability of the consumers [1, 2]. The current legal framework establishes that hospital facilities are responsible for guaranteeing the safety of the food they produce and/or serve, and to implement all preventive measures necessary to minimize the risk of exacerbating illness or spreading a food-borne disease [3]. In this sense, food allergens must be managed in a way that avoids the unintended presence of particular allergens, or clearly states on the label or informs the consumer of their presence, where necessary.
在医院,考虑到消费者的脆弱性,食品卫生被认为是预防并发症和缩短住院时间的一个重要因素[1,2]。目前的法律框架规定,医院设施有责任保证其生产和/或供应的食品的安全,并实施所有必要的预防措施,以最大限度地降低疾病恶化或传播食源性疾病的风险[3]。从这个意义上说,食品过敏原的管理方式必须避免特定过敏原的意外存在,或在标签上明确说明或在必要时告知消费者其存在。
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引用次数: 0
Development of an Improved Isocratic HPLC Method for the Determination of Gallic Acid, Caffeine and Catechins in Tea 茶中没食子酸、咖啡因和儿茶素含量测定方法的建立
Pub Date : 2018-06-25 DOI: 10.15226/JNHFS.2018.001135
S. Kingori, Po Ongoma, So Ochanda
A simple and sensitive reversed phase high performance liquid chromatographic (HPLC) method has been developed for the determination of biomolecules in different types of tea. Most of the High Performance Liquid Chromatography (HPLC) methods used for the determination of tea biochemicals include gradient elution systems which involve expensive instrumentation. The aim of this study was to develop an improved sensitive, fast, cost effective and accurate isocratic HPLC method with photo diode array (PDA) detection for analysis of Gallic acid, caffeine and catechins in tea, using a suitable internal standard. The developed HPLC analytical method consisted of a C6phenyl column and anisocratic elution system of Water: acetonitrile: methanol: Ortho phosphoric acid: ethyl acetate (77.5:18:2.0:0.5:2.0 v/v/v/v/v) at a flow rate of 1.0 mL/min. The detection wavelength was chosen at 278 nm with guaiacol (2-methoxyphenol) used as an internal standard as it did not co-elute with the analytes of interest. Statistical comparison of the analytical result obtained for gallic acid, caffeine and catechins in four tea types green CTC (cut, tear and curl), black CTC, green orthodox and black orthodox using the developed method and ISO 1405-2:2005(E) method did not show significant difference. The method has been validated and has shown consistency to qualitative and quantitative determination of the tea biomolecules of interest.
建立了一种简单灵敏的反相高效液相色谱法测定不同类型茶叶中生物分子的方法。用于测定茶叶生物化学物质的大多数高效液相色谱(HPLC)方法包括梯度洗脱系统,该系统涉及昂贵的仪器。本研究的目的是开发一种改进的灵敏、快速、经济高效和准确的等度HPLC方法,用光电二极管阵列(PDA)检测,使用合适的内标物分析茶中的没食子酸、咖啡因和儿茶素。所开发的HPLC分析方法由C6-苯基柱和水:乙腈:甲醇:正磷酸:乙酸乙酯(77.5:18:2.0:0.5:2.0 v/v/v/v)的各向异性洗脱系统组成,流速为1.0mL/min。检测波长选择在278nm,使用愈创木酚(2-甲氧基苯酚)作为内标,因为它不与感兴趣的分析物共洗脱。使用所开发的方法和ISO 1405-2:2005(E)方法对四种茶型绿色CTC(切、撕和卷曲)、黑色CTC、绿色正统茶和黑色正统茶中没食子酸、咖啡因和儿茶素的分析结果进行统计比较,没有显示出显著差异。该方法已得到验证,与感兴趣的茶叶生物分子的定性和定量测定结果一致。
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引用次数: 3
How Lifestyle Can Improve Health Expenses 生活方式如何提高医疗费用
Pub Date : 2018-06-06 DOI: 10.15226/JNHFS.2018.001134
R. Verna
Physical activity is important for the prevention of many diseases and to improve the conditions of sick people. “Exercise is medicine” is the new address for prevention and therapy. The boys also benefit of the sport activity for their psychological maturation. In addition, there is the damage from poor nutrition, alcohol dependence and the overuse of pharmacologically active substances, misuse of drugs, even those permitted. It is therefore necessary to increase the quantity/quality of time devoted to physical activity, both at school and outside school, but above all, it is vital the dissemination of knowledge of the problem. A widespread information / training, along with a sport and proper medical supervision into every type of school, would lead to a sharp reduction in public spending, much higher than the 80 million of which we have just spoken, with an almost negligible investment. The ideal would be to set up in School a course of education to health, with the principles of nutrition and physical activity, in order to improve the lifestyles and reduce health spending through health education, proper nutrition and sports activities. 1-2 hours a week would be enough to communicate to children, and indirectly their families and the families of the future, what are the criteria for a healthy life. It is however, necessary to have suitably qualified teachers for the treatment and dissemination of health prevention principles of proper nutrition and the correct approach to sports activities. A specific training should be therefore held in the University. Health education cannot be done by the science teachers or those of motor sciences, alone; they must have a physician specially trained to coordinate, perhaps in co-presence, the interventions.
体育活动对预防许多疾病和改善病人的状况很重要。“运动就是医学”是预防和治疗的新理念。男孩们也从体育活动中受益于他们的心理成熟。此外,营养不良、酒精依赖、过度使用药物活性物质、滥用药物,甚至是允许的药物,都会造成损害。因此,有必要增加学校内外用于体育活动的时间数量/质量,但最重要的是,传播有关这一问题的知识至关重要。广泛的信息/培训,加上对每种类型的学校进行体育运动和适当的医疗监督,将导致公共支出的大幅减少,远远高于我们刚刚谈到的8000万,而投资几乎可以忽略不计。理想的做法是在学校开设一门健康教育课程,遵循营养和体育活动的原则,通过健康教育、适当的营养和体育运动来改善生活方式,减少健康支出。每周1-2个小时就足以与孩子们,间接地与他们的家人和未来的家庭交流,健康生活的标准是什么。然而,有必要有适当的合格教师来治疗和传播适当营养和正确体育活动方法的健康预防原则。因此,应在该大学进行专门培训。健康教育不能由科学教师或运动科学教师单独完成;他们必须有一位受过专门训练的医生来协调干预措施,也许是在共同在场的情况下。
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引用次数: 0
Whole Grains in Amelioration of Metabolic Derangements. 粗粮改善代谢紊乱。
Pub Date : 2016-01-01 Epub Date: 2016-10-24 DOI: 10.15226/jnhfs.2016.00173
Samir Develaraja, Anup Reddy, Mukesh Yadav, Shalini Jain, Hariom Yadav

Daily diet influences whole body metabolism, and intricately linked to the prevention or progression of metabolic diseases including obesity, diabetes and cardiovascular diseases. Several epidemiological and large scale studies have shown that diets enriched with whole grains improves metabolic function and protect from the development of metabolic diseases. Direct impact of whole grain diet can be mediated on several levels of metabolic functions i.e. reduced glycemic index, improved fat oxidation potential, increased cholesterol clearance or decreased cholesterol biosynthesis and modulation of gut microbiome. In this article we reviewed several studies indicating the beneficial effects of whole grain diets on metabolic functions, as well as discussed the potential active phytochemicals present in these whole grain foods to contribute in modulation of metabolic function in our body.

日常饮食影响全身代谢,并与代谢疾病(包括肥胖、糖尿病和心血管疾病)的预防或进展密切相关。一些流行病学和大规模研究表明,富含全谷物的饮食可以改善代谢功能,防止代谢疾病的发生。全谷物饮食的直接影响可以通过几个水平的代谢功能介导,即降低血糖指数、改善脂肪氧化电位、增加胆固醇清除或减少胆固醇生物合成和调节肠道微生物群。在本文中,我们回顾了几项表明全谷物饮食对代谢功能有益的研究,并讨论了这些全谷物食物中存在的潜在活性植物化学物质在调节人体代谢功能方面的作用。
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引用次数: 16
Healthy Hunger-Free Kids Act Increases Phytochemicals in Menus and Curriculum Furthers Identification of Phytochemical-Rich Foods. 健康无饥饿儿童法案增加菜单和课程中的植物化学物质,进一步确定富含植物化学物质的食物。
Pub Date : 2016-01-01 Epub Date: 2016-03-09 DOI: 10.15226/jnhfs.2016.00156
D Brewer, S Hershberger, L Gaetke

Objective: This study evaluated whether providing the Fruits and Vegetables (F/V) required by the Healthy Hunger-Free Kids Act (HHFKA) increased phytochemical/antioxidant content of school lunches. Additionally, the ability of adolescents to apply their nutritional knowledge following participation in a nutrition-focused science-based curriculum was assessed.

Methods: Changes in antioxidant/phytochemical content from F/V offered in school lunch menus were analyzed Pre-and Post-HHFKA. Food logs completed by 717 youth aged 10-18 were analyzed for correctly identifying "fighting foods".

Results: Significant increases in antioxidant/phytochemical content resulted following implementation of HHFKA (P<0.05). Seventy-five percent [0, 100] of the time students accurately identified "fighting foods" in their one-day in-school food log (n=468).

Conclusions and implications: Creatively incorporating nutrition education into core curriculum, when paired with a supportive built environment that increases F/V access (HHFKA), generates a multilevel intervention promoting F/V consumption among school-aged youth.

目的:本研究评估提供健康无饥饿儿童法案(HHFKA)所要求的水果和蔬菜(F/V)是否增加了学校午餐的植物化学/抗氧化剂含量。此外,还评估了青少年在参加以营养为重点的科学课程后应用其营养知识的能力。方法:分析hfka前后学校午餐菜单中F/V抗氧化/植物化学成分的变化。研究人员分析了717名年龄在10-18岁的青少年完成的食物日志,以正确识别“有害食物”。结果:实施hfka后,抗氧化剂/植物化学物质含量显著增加(P)。75%[1,100]的学生在他们一天的学校食物记录中准确地识别出“有害食物”(n=468)。结论和意义:创造性地将营养教育纳入核心课程,与增加食物/电视获取的支持性建筑环境(hfka)相结合,产生了促进学龄青少年食物/电视消费的多层次干预。
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引用次数: 2
Development of a Diet Quality Score for Infants and Toddlers and its association with weight. 制定婴幼儿饮食质量评分及其与体重的关系。
Pub Date : 2016-01-01 Epub Date: 2016-10-18 DOI: 10.15226/jnhfs.2016.00171
Elaine M Ríos, Olga Sinigaglia, Beatriz Diaz, Maribel Campos, Cristina Palacios

Objective: To create a Diet Quality Index Score (DQIS) for infants and toddlers and to assess its relative validity.

Design: Three DQIS were created (0-5, 8-11 and 12-24 months) based on a validated food frequency questionnaire (FFQ). Nine components were included, scored from 0 (inadequate) to 5 (adequate consumption) based on guidelines for timing of food's introduction and portion sizes; the component on breastfeeding (Yes/No) was scored (0-15). Infants 6-7 months were excluded as new foods are introduced during this period. The total score (0-55 points) was categorized as Excellent (≥45), Good (35-44), Needs improvement (25-34), and Poor (<25). Relative validity was assessed against weight status among a sample of 296 children using logistic regression.

Results: In infants 0-5 months (n=100), mean DQIS was 42.4±9.3 and 52% had 'Excellent' diets. In infants 8-11 months (n=42), mean DQIS was 36.1±7.7 and most had 'Good' diets (47.6%). Among toddlers 12-24 months (n=117), mean DQIS was 25.7±8.0 and most had 'Poor' diets (50.4%). There was a trend for a higher odd of Excessive weight in those with 'Poor' diets compared to those with 'Excellent' diets, after controlling for confounders (OR 2.01; 95% CI: 0.85, 5.18).

Conclusions: These scores could be used to assess diet quality in infants and toddlers. There was a trend for a higher odd of Excessive weight among those with 'Poor' diets. To our knowledge, this is the first algorithm for the assessment of diet quality in infants and toddlers considering intake of each food group and their portion sizes.

目的:为婴幼儿创建饮食质量指数评分(DQIS),并评估其相对有效性:为婴幼儿创建饮食质量指数(DQIS),并评估其相对有效性:设计:根据经过验证的食物频率问卷(FFQ),创建了三个 DQIS(0-5 个月、8-11 个月和 12-24 个月)。其中包括九项内容,根据食物引入时间和份量指南,从 0 分(摄入不足)到 5 分(摄入充足)不等;母乳喂养内容(是/否)的评分为 0-15 分。6-7个月的婴儿不包括在内,因为这一时期会添加新的食物。总分(0-55 分)分为优(≥45 分)、良(35-44 分)、需改进(25-34 分)和差(结果:0-5 个月婴儿(100 人)的 DQIS 平均值为 42.4±9.3,52% 的婴儿饮食为 "优"。在 8-11 个月的婴儿(42 人)中,DQIS 平均值为 36.1±7.7,大多数婴儿的饮食为 "良好"(47.6%)。在 12-24 个月的学步儿童(人数=117)中,DQIS 的平均值为 25.7±8.0,大多数饮食习惯为 "差"(50.4%)。在控制了混杂因素后(OR 2.01; 95% CI: 0.85, 5.18),与饮食 "优良 "的幼儿相比,饮食 "不良 "的幼儿体重超标的几率呈上升趋势:这些评分可用于评估婴幼儿的饮食质量。结论:这些评分可用于评估婴幼儿的饮食质量,饮食 "差 "的婴幼儿体重超标的几率较高。据我们所知,这是第一种评估婴幼儿饮食质量的算法,它考虑到了每类食物的摄入量及其份量。
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引用次数: 0
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Journal of nutritional health & food science
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