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Reassuring Quantitative Analysis of Glyphosate and Aminomethylphosphonic Acid Levels in Breast Milk Using Liquid Chromatography Mass Spectrometry. 利用液相色谱质谱法对母乳中草甘膦和氨甲基膦酸含量进行可靠的定量分析
IF 2.1 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2024-09-01 Epub Date: 2024-06-20 DOI: 10.1089/bfm.2024.0118
Roman Pawlak, Ashley Wooten, Mustafa Selim, Kimberly Kew

Purpose: The World Health Organization's International Agency on Research for Cancer has determined that glyphosate is "probably carcinogenic to humans." There is a great public interest to investigate whether glyphosate are detected in breast milk. Thus, the goal of this study was to assess the concentration of glyphosate and its main metabolite in breast milk. Materials and Methods: Liquid chromatography was performed at 25°C using a Luna NH2, 50 × 2 mm, 3⎛ m (Phenomenex) analytical column. Electrospray ionization mass spectrometry was collected using negative ionization mode. The calibration curve for glyphosate ranged from 10 to 250 ng/mL. The detection limit was 1 ng/mL. Results: Breast milk samples were collected from 74 women, which included vegans (n = 26), vegetarians (n = 22), and nonvegetarians (n = 26). One of the 74 milk samples contained a detectable concentration of glyphosate and an additional 7 were found to contain aminomethylphosphonic acid. Conclusions: In breast milk samples collected mainly from women residing in urban regions of the United States, glyphosate detection was rare. Consistently, breastfed infants have a low or minimal risk of being exposed to glyphosate through ingestion of mother's milk. It is possible that the presence/absence and/or level of concentration of milk glyphosate depend on a place of residency and time of breastfeeding vis-à-vis time of its agricultural application.

目的:世界卫生组织国际癌症研究机构已确定草甘膦 "可能对人类致癌"。调查母乳中是否检测到草甘膦引起了公众的极大兴趣。因此,本研究的目的是评估草甘膦及其主要代谢物在母乳中的浓度。材料和方法:使用 Luna NH2、50 × 2 mm、3⎛ m(Phenomenex)分析柱,在 25°C 下进行液相色谱分析。电喷雾电离质谱采用负离子模式。草甘膦的校准曲线范围为 10 至 250 纳克/毫升。检测限为 1 纳克/毫升。结果收集了 74 名妇女的母乳样本,其中包括素食者(26 人)、素食者(22 人)和非素食者(26 人)。在 74 份母乳样本中,有一份样本含有可检测浓度的草甘膦,另有 7 份样本含有氨甲基膦酸。结论在主要从居住在美国城市地区的妇女采集的母乳样本中,草甘膦的检测结果非常罕见。母乳喂养的婴儿通过摄入母奶接触草甘膦的风险很低或极低。母乳中草甘膦的存在/不存在和/或浓度水平可能取决于居住地和哺乳时间与农业施用草甘膦的时间。
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引用次数: 0
Lactoferrin Concentration in Breast milk-Unidentified Corelates! 母乳中的乳铁蛋白浓度--不明核酸!
IF 2.1 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2024-09-01 Epub Date: 2024-07-10 DOI: 10.1089/bfm.2024.0168
Supreet Khurana
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引用次数: 0
Mother's Milk Donation to a Human Milk Bank During Bereavement: Circumstances Associated with Completing the Donation Process. 丧亲期间向母乳库捐赠母乳:完成捐献过程的相关情况。
IF 2.1 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2024-09-01 Epub Date: 2024-07-04 DOI: 10.1089/bfm.2024.0153
Mahati Pidaparti, Grace Knowles, Natalia Henner, Jessica T Fry, Summer G Kelly, Jinnene Hoggarth, Daniel T Robinson

Background: Bereaved mothers describe positive experiences donating breast milk and negative experiences when not informed of opportunities to donate. Predictors of whether mothers donate milk are unknown, impairing efforts to optimize support in completing donation. Objective: To define circumstances associated with completing mother's milk (MM) donation during bereavement. Methods: A retrospective cohort study included dyads of bereaved mothers and their deceased children if a child's death occurred on-site at a quaternary care children's hospital during 2016-2020, the child had documentation of MM availability, and age at death <24 months. The primary outcome was the completion of MM donation to the milk bank. Multivariate logistic regression measured associations between clinical variables and odds of completion. Results: Of 124 deceased children with documented MM exposure, 34 mothers (28%) of 35 of those children completed MM donation, donating a mean of 13.7 liters (SD 16.8). The child's race/ethnicity documented in the medical record was White for 25 (71%), Black/African American (AA) for 1 (3%), Asian for 1 (3%), and Hispanic/Latino for 8 (23%). Referenced to mothers of White children, being a mother of an AA [OR 0.05 (95% CI: 0.01-0.43)] or Asian [0.08 (0.01-0.75)] child was associated with lower odds of donation. Referenced to mothers delivering full term (≥37 weeks'), mothers delivering <34 weeks showed higher odds [5.0 (1.5-17.5)] of donation. Conclusion: Relatively few bereaved mothers of children with indicators of MM exposure completed donation. The results suggest an opportunity to ensure bereaved mothers are uniformly informed and supported in donating.

背景:失去亲人的母亲描述了捐献母乳的积极经历,以及未被告知捐献机会时的消极经历。母亲是否捐献母乳的预测因素尚不清楚,这影响了为完成捐献提供最佳支持的工作。目标:确定与丧亲期间完成母乳(MM)捐赠相关的情况。方法:采用回顾性队列研究的方法:一项回顾性队列研究纳入了丧亲母亲及其已故子女的二人组,条件是:2016-2020 年期间,子女死亡发生在一家四级护理儿童医院现场,子女有可获得 MM 的记录,以及死亡时的年龄:在124名有MM接触记录的死亡儿童中,其中35名儿童的34名母亲(28%)完成了MM捐献,平均捐献量为13.7升(标清16.8)。病历中记录的儿童种族/族裔为白人 25 人(占 71%)、黑人/非洲裔美国人 1 人(占 3%)、亚裔 1 人(占 3%)、西班牙裔/拉丁美洲裔 8 人(占 23%)。与白人母亲相比,AA [OR 0.05 (95% CI: 0.01-0.43)] 或亚裔 [0.08 (0.01-0.75)] 母亲的捐献几率较低。参考足月分娩(≥37 周)的母亲、分娩的母亲 结论:具有 MM 暴露指标的儿童的丧母母亲完成捐献的人数相对较少。结果表明,有机会确保丧子母亲在捐献时得到统一的信息和支持。
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引用次数: 0
Yes, Breastfeeding Is More Than Just Nutrition. 是的,母乳喂养不仅仅是营养。
IF 2.1 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2024-09-01 Epub Date: 2024-08-19 DOI: 10.1089/bfm.2024.0255
Arthur I Eidelman
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引用次数: 0
Setting the Agenda for Patient-Centered Research in Infant and Young-Child Feeding: Results from the Academy of Breastfeeding Medicine and Reaching Our Sisters Everywhere. 制定以患者为中心的婴幼儿喂养研究议程:母乳喂养医学学会的成果》和《走遍我们的姐妹》。
IF 2.1 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2024-09-01 Epub Date: 2024-06-28 DOI: 10.1089/bfm.2023.0297
Ann Kellams, Laura Kair, Kimberley Broomfield-Massey, Kimberly D Harper, Kimarie Bugg, Alison Stuebe

Background: Breastfeeding is critically important for optimal health of both birthing people and their infants. Shared, patient-centered goals of how health care team members, community groups, and families can help facilitate breastfeeding success are needed, as are ways to define and measure what breastfeeding success looks like from the patient's perspective. Methods: The Academy of Breastfeeding Medicine and Reaching Our Sisters Everywhere's collaborated in a multi-methods approach to identify breastfeeding priorities most important to parents. Results: We identified (1) Key components of a successful breastfeeding journey defined by parents and families, (2) Research priorities that will enable families to achieve breastfeeding. Conclusion: Dissemination of these findings can foster research efforts that are codesigned with birthing parents and families and reflect their priorities.

背景:母乳喂养对分娩者及其婴儿的最佳健康至关重要。医护团队成员、社区团体和家庭需要共同制定以患者为中心的目标,以帮助促进母乳喂养的成功,同时也需要从患者的角度来定义和衡量母乳喂养的成功。方法:母乳喂养医学学会和 "走遍天下姐妹 "组织合作,采用多种方法确定母乳喂养对父母最重要的优先事项。结果:我们确定了:(1)由父母和家庭定义的成功母乳喂养历程的关键要素;(2)能够帮助家庭实现母乳喂养的研究重点。结论:传播这些发现可以促进与分娩父母和家庭共同设计并反映其优先事项的研究工作。
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引用次数: 0
World Breastfeeding Week 2024: Closing the Gap-Breastfeeding Support for All. 2024 年世界母乳喂养周:缩小差距--为所有人提供母乳喂养支持。
IF 2.1 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2024-09-01 Epub Date: 2024-08-19 DOI: 10.1089/bfm.2024.0254
Elien Rouw
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引用次数: 0
The Effect of Supplemental Feeding Tube Device on Time to Transition to Exclusive Breastfeeding and Discharge: A Randomized Controlled Trial with Preterm Infants. 辅食管装置对过渡到纯母乳喂养和出院时间的影响:早产儿随机对照试验。
IF 2.1 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2024-09-01 Epub Date: 2024-06-21 DOI: 10.1089/bfm.2024.0084
Ciler Aydin, Aynur Aytekin Ozdemir, Hasan Kahveci

Aim: This study investigated the effect of supplemental feeding tube device (SFTD) method on time to transition to exclusive breastfeeding and discharge time in preterm infants. Methods: This randomized controlled trial was conducted in the neonatal intensive care unit of a public hospital in Turkey (Clinical Trial Number: NCT05815706). The sample consisted of 65 preterm infants randomized into a control (n = 32) and an experimental (n = 33) group. The experimental group participants were SFTD-fed until they switched to exclusive breastfeeding. The control group participants were fed according to the routine procedure. Data were collected using a questionnaire, a Preterm Infant Monitoring Form, and the LATCH Breastfeeding Assessment Tool. The data were analyzed using numbers, percentage distributions, means, standard deviations, Pearson's chi-square test, and independent samples t-test. The study was approved by an Ethics Committee. Permission was obtained from the hospital. Informed consent was obtained from all parents. Results: The experimental group (123.64 ± 63.25 hours) demonstrated an earlier transition to exclusive breastfeeding compared with the control group (187.50 ± 95.30 hours) (p < 0.05). The experimental group (361.45 ± 110.46 hours) had significantly shorter hospital stays than the control group (479.25 ± 163.17 hours). The experimental group (35.33 ± 1.14 weeks) had a significantly younger gestational age at discharge than the control group (35.97 ± 1.03 weeks). Conclusion: The SFTD is an alternate supportive feeding method that helps preterm infants switch to exclusive breastfeeding sooner, have shorter hospital stays, and have a younger gestational age at discharge than their bottle-fed counterparts.

目的:本研究探讨了补充喂食管装置(SFTD)方法对早产儿过渡到纯母乳喂养时间和出院时间的影响。方法本随机对照试验在土耳其一家公立医院的新生儿重症监护室进行(临床试验编号:NCT05815706)。样本包括 65 名早产儿,随机分为对照组(32 人)和实验组(33 人)。实验组的参与者在转为纯母乳喂养前一直采用 SFTD 喂养。对照组按照常规程序喂养。通过问卷、早产儿监测表和 LATCH 母乳喂养评估工具收集数据。数据分析采用数字、百分比分布、平均值、标准差、皮尔森卡方检验和独立样本 t 检验。本研究获得了伦理委员会的批准。研究获得了医院的许可。所有家长均已知情同意。结果与对照组(187.50 ± 95.30 小时)相比,实验组(123.64 ± 63.25 小时)更早过渡到纯母乳喂养(P < 0.05)。实验组的住院时间(361.45 ± 110.46 小时)明显短于对照组(479.25 ± 163.17 小时)。实验组(35.33 ± 1.14 周)出院时的胎龄明显小于对照组(35.97 ± 1.03 周)。结论SFTD是一种替代性支持喂养方法,可帮助早产儿更快地转为纯母乳喂养,缩短住院时间,出院时的胎龄也比用奶瓶喂养的早产儿小。
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引用次数: 0
YouTube Video Clips on Breastfeeding Education and Promotion for Arabic-Speaking Populations: A Social Media Content Analysis. 针对阿拉伯语人群的 YouTube 母乳喂养教育和宣传视频剪辑:社交媒体内容分析。
IF 2.1 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2024-09-01 Epub Date: 2024-07-25 DOI: 10.1089/bfm.2024.0149
Fatmah Almoayad, Anwar Alhashem, Reem Alotaibi, Renad Alashwl, Alanoud Albahouth, Nada Benajiba, Patricia J Kelly, Basil H Aboul-Enein

Background/Objective: Although the benefits of breastfeeding are well-documented and widely recognized, reports indicate that optimal breastfeeding rates are low in Arabic-speaking countries. This is a significant concern given the health benefits associated with breastfeeding for both infants and mothers. Previous research has shown that education interventions can increase breastfeeding knowledge, attitudes, and practices in Arabic-speaking populations. The social media platform YouTube holds significant potential for distributing customized health education for diverse audiences; specifically, this platform has the potential to empower mothers and normalize long-term breastfeeding. The aim of this study was to evaluate the quality of YouTube videos on breastfeeding available in the Arabic language. Methods: We used standard procedures to search YouTube for Arabic breastfeeding videos posted on YouTube in December 2023. Videos were evaluated using the three scales of the DISCERN quality evaluation instrument (reliability, information quality, video quality) and total score. Comparative statistics were generated. Results: In total, 165 videos met the inclusion criteria, with 29.7% in the Education category; 43.6% were in Egyptian Arabic dialect. Almost all (91.75%) of the educational videos had a "medium" quality assessment. Educational videos and those using health professionals had higher quality assessments than those in other categories or done with other speakers. Conclusion: The results of this review suggest that most content on the topic of breastfeeding was of only medium reliability and informational quality. New mothers seeking breastfeeding information or support may be in need of specific problem-solving information at a time when they are living with the often-difficulty reality of caring for a newborn or very young infant. There is a clear need for accurate, culturally congruent information to effectively support breastfeeding in Arabic-speaking countries. Future efforts should focus on improving the quality of online health education content, with implications for public health strategies and policy development.

背景/目标:尽管母乳喂养的益处有据可查并得到广泛认可,但有报告显示,阿拉伯语国家的最佳母乳喂养率很低。鉴于母乳喂养对婴儿和母亲的健康都有好处,这是一个值得关注的重大问题。以往的研究表明,教育干预措施可以提高阿拉伯语人群的母乳喂养知识、态度和实践。社交媒体平台 YouTube 在为不同受众提供定制化健康教育方面具有巨大潜力;特别是,该平台具有增强母亲能力和使长期母乳喂养正常化的潜力。本研究旨在评估 YouTube 上阿拉伯语母乳喂养视频的质量。研究方法我们使用标准程序在 YouTube 上搜索 2023 年 12 月发布的阿拉伯语母乳喂养视频。使用 DISCERN 质量评估工具的三个量表(可靠性、信息质量、视频质量)和总分对视频进行评估。并生成比较统计数据。结果共有 165 部视频符合纳入标准,其中 29.7% 属于教育类;43.6% 为埃及阿拉伯语方言。几乎所有教育视频(91.75%)的质量评估为 "中等"。与其他类别或使用其他语言的视频相比,教育类视频和使用卫生专业人员的视频的质量评估更高。结论本次审查的结果表明,大多数有关母乳喂养主题的内容在可靠性和信息质量方面都处于中等水平。新妈妈们在寻求母乳喂养信息或支持时,可能需要具体的解决问题的信息,而此时她们正生活在照顾新生儿或年幼婴儿的困难现实中。阿拉伯语国家显然需要准确的、与文化相一致的信息来有效地支持母乳喂养。未来的工作重点应放在提高在线健康教育内容的质量上,这将对公共卫生战略和政策制定产生影响。
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引用次数: 0
Impact of the 2022 Infant Formula Shortage on Neonatal Intensive Care Units. 2022 年婴儿配方奶粉短缺对新生儿重症监护病房的影响。
IF 2.1 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2024-08-29 DOI: 10.1089/bfm.2024.0127
La'Toya James-Davis, Caitlin Drumm, Jeanne Krick, Rasheda Vereen

Objective: The aim of this study was to examine effects of the 2022 infant formula shortage as experienced by neonatal intensive care units (NICUs) in the United States, a previously unreported perspective. Methods: A mixed-method approach was utilized. Data were collected using an online survey of NICU medical directors. Quantitative data were analyzed with descriptive statistics and Student's t test. Thematic analysis was utilized to make sense of patterns within the qualitative data. Results: Responses from 139 medical directors were received. Both academic (41.7%) and community (58.3%) NICUs were represented among respondents. Thirty-nine percent of NICU medical directors reported an impact on their unit by the infant formula shortage. Within the qualitative data four themes were revealed as follows: alterations to discharge planning, policy modifications, suboptimal solutions, and extraordinary measures. These themes may inform strategies for mitigation of future infant formula shortages. Conclusions: NICUs were significantly impacted by the infant formula shortage with likely lasting effects. From the reported experiences, clear recommendations have been formed to minimize effects of future infant formula shortages.

研究目的本研究旨在从美国新生儿重症监护室(NICU)的角度研究 2022 年婴儿配方奶粉短缺的影响。研究方法采用混合方法。通过对新生儿重症监护室医务主任进行在线调查收集数据。采用描述性统计和学生 t 检验对定量数据进行分析。采用主题分析法来理解定性数据中的模式。结果:共收到 139 位医务主任的回复。受访者中既有学术重症监护室(41.7%),也有社区重症监护室(58.3%)。39%的新生儿重症监护病房医务主任表示,婴儿配方奶粉短缺对他们的病房造成了影响。定性数据揭示了以下四个主题:改变出院计划、政策修改、次优解决方案和非常措施。这些主题可为今后缓解婴儿配方奶粉短缺的策略提供参考。结论:新生儿重症监护室受到了婴儿配方奶粉短缺的严重影响,而且这种影响可能会持续很长时间。根据所报告的经验,我们提出了明确的建议,以尽量减少未来婴儿配方奶粉短缺的影响。
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引用次数: 0
Effect of Delayed Cord Clamping on Breastfeeding Behaviors During the First Breastfeed: A Randomized Controlled Study. 延迟脐带剪断对首次哺乳期母乳喂养行为的影响:随机对照研究
IF 2.1 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2024-08-01 Epub Date: 2024-05-13 DOI: 10.1089/bfm.2024.0080
Nihan Hilal Hoşağası, Sami Güngör

Objective: Delayed cord clamping (DCC) may increase the success of breastfeeding by improving neurological and cardiovascular function in neonates. In this study, we investigated the impact of DCC on breastfeeding behaviors, neonatal activity status, and maternal satisfaction during the first breastfeeding. Methods: This randomized controlled study was conducted in a tertiary hospital in Turkey with 100 term infants delivered by elective cesarean section with spinal anesthesia. The participants were randomly assigned to the early cord clamping (ECC) group or DCC group. The Infant Breastfeeding Assessment Tool (IBFAT) was used to assess infant alertness, breastfeeding behaviors, and maternal satisfaction with breastfeeding within the first 2 hours of life. Results: Scores on the IBFAT were significantly higher in the DCC group compared with the ECC group (p = 0.02). Maternal satisfaction with breastfeeding did not differ between the groups (p = 0.3). Infant alertness tended to be better in the DCC group, but the difference was not statistically significant (p = 0.08). Conclusion: The results of this study indicated that DCC was associated with more favorable breastfeeding behaviors compared with ECC.

目的延迟脐带夹闭(DCC)可改善新生儿的神经和心血管功能,从而提高母乳喂养的成功率。在这项研究中,我们调查了延迟脐带夹闭对母乳喂养行为、新生儿活动状态和首次母乳喂养期间产妇满意度的影响。研究方法这项随机对照研究在土耳其的一家三级医院进行,100 名足月儿在脊髓麻醉下通过选择性剖腹产分娩。参与者被随机分配到早期脐带钳夹(ECC)组或DCC组。婴儿母乳喂养评估工具(IBFAT)用于评估婴儿的警觉性、母乳喂养行为以及母亲对出生后 2 小时内母乳喂养的满意度。结果DCC 组的 IBFAT 分数明显高于 ECC 组(p = 0.02)。母亲对母乳喂养的满意度在各组之间没有差异(p = 0.3)。DCC组的婴儿警觉性更高,但差异无统计学意义(p = 0.08)。结论本研究结果表明,DCC 与 ECC 相比,DCC 与更有利的母乳喂养行为相关。
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引用次数: 0
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Breastfeeding Medicine
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