N. I. Pryanikova, Anna A. Bykadorova, O. Polikarpova, I. Shchelkunova, M. Petrova
Background: Dysphagia of various origins is widespread. There is a high risk of developing formidable complications: malnutrition, dehydration, weight loss, airway obstruction, aspiration pneumonia. The product Softia S is used to solve the problems of swallowing liquids. The Ministry of Agriculture, Forestry and Fisheries of Japan financed this study within the framework of the 8-Point Cooperation Plan presented by the Prime Minister of Japan S. Abe to the President of the Russian Federation V. V. Putin in May 2016. Aims: Assessment of the efficacy and safety of NUTRIs Softia S product for patients with dysphagia of various origins. Materials and methods: Complex assessment of dysphagia included speech therapy, video fluoroscopy and video laryngoscopy with assessment of swallowing function Rosenbek (PAS) and FEDSS scales. Patients were divided into 2 groups (experiment and control). The study lasted 14 days. Examination by a speech therapist and a nutritionist was carried out daily. On the 1st and 14th days, laboratory parameters were monitored, and the patients body weight was determined. Results: The study included 30 patients with mild dysphagia. By the end of the study, 8 people in the experimental group showed a restoration of the swallowing function, residual effects in the form of choking persisted in 7 people. In the control group, a slight improvement was observed in 2 patients, 13 had no changes. The most significant changes were found in the experimental group for the indicators "Time of eating" ("Breakfast", on average, 3.7 minutes, p=0.0033; "Lunch", on average, 6.9 minutes, p 0.0001); "The number of chokes after hydration" ("Breakfast" by an average of 7.0, p 0.0001; "Lunch" by an average of 8.1, p 0.0001; "Dinner" by an average of 6.8, p 0.0001); "The number of chokes during hydration" ("Breakfast" by an average of 8.8, p 0.0001; "Lunch" by an average of 12.1, p 0.0001; "Dinner" by an average of 8.7, p 0.0001). The number of dysphonia cases with sputum significantly decreased only in the experimental group. Conclusions: Softia S can be used in complex therapy for dysphagia by reducing the amount of choking after and during hydration and time of eating and dysphonia cases with sputum.
{"title":"Efficacy of NUTRI’s Softia S Product in Patients with Dysphagia","authors":"N. I. Pryanikova, Anna A. Bykadorova, O. Polikarpova, I. Shchelkunova, M. Petrova","doi":"10.17816/CLINUTR62329","DOIUrl":"https://doi.org/10.17816/CLINUTR62329","url":null,"abstract":"Background: Dysphagia of various origins is widespread. There is a high risk of developing formidable complications: malnutrition, dehydration, weight loss, airway obstruction, aspiration pneumonia. The product Softia S is used to solve the problems of swallowing liquids. The Ministry of Agriculture, Forestry and Fisheries of Japan financed this study within the framework of the 8-Point Cooperation Plan presented by the Prime Minister of Japan S. Abe to the President of the Russian Federation V. V. Putin in May 2016. Aims: Assessment of the efficacy and safety of NUTRIs Softia S product for patients with dysphagia of various origins. Materials and methods: Complex assessment of dysphagia included speech therapy, video fluoroscopy and video laryngoscopy with assessment of swallowing function Rosenbek (PAS) and FEDSS scales. Patients were divided into 2 groups (experiment and control). The study lasted 14 days. Examination by a speech therapist and a nutritionist was carried out daily. On the 1st and 14th days, laboratory parameters were monitored, and the patients body weight was determined. Results: The study included 30 patients with mild dysphagia. By the end of the study, 8 people in the experimental group showed a restoration of the swallowing function, residual effects in the form of choking persisted in 7 people. In the control group, a slight improvement was observed in 2 patients, 13 had no changes. The most significant changes were found in the experimental group for the indicators \"Time of eating\" (\"Breakfast\", on average, 3.7 minutes, p=0.0033; \"Lunch\", on average, 6.9 minutes, p 0.0001); \"The number of chokes after hydration\" (\"Breakfast\" by an average of 7.0, p 0.0001; \"Lunch\" by an average of 8.1, p 0.0001; \"Dinner\" by an average of 6.8, p 0.0001); \"The number of chokes during hydration\" (\"Breakfast\" by an average of 8.8, p 0.0001; \"Lunch\" by an average of 12.1, p 0.0001; \"Dinner\" by an average of 8.7, p 0.0001). The number of dysphonia cases with sputum significantly decreased only in the experimental group. Conclusions: Softia S can be used in complex therapy for dysphagia by reducing the amount of choking after and during hydration and time of eating and dysphonia cases with sputum.","PeriodicalId":92235,"journal":{"name":"Journal of clinical nutrition and metabolism","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82898948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Krylov, I. Savin, S. Sviridov, I. Vedenina, M. Petrova, A. Vorobyev, M. Rubanes
Critically ill patients often develop hyperglycemia because of the metabolic response to trauma and stress. In response to any form of damage to the organism, it reacts by increasing its own glucose production which subsequently causes hyperglycemia. This adaptive reaction of the organism is directed to aid in the rapid restoration after the damage. Therefore, glucose is an indispensable substrate in the critically ill which aids the reparation process. Severe and persistent hyperglycemia is associated with unfavorable outcomes and is considered to be an independent predictor of in-hospital mortality. The discussion remains on whether hyperglycemia is just a marker of increased stress which makes it a surrogate indicator of disease severity or if it is the reason for the unfavorable outcome. A few years ago, several published articles suggested that a tight glycemic control within the normal range improves treatment outcome. Over time, researchers have changed their point of view and currently there is a discussion on this matter in the scientific literatures. At the same time, the question of what glycemic level should be maintained for patients in the Neurological Intensive Care Unit is a matter of discussion. In this review, the authors analyzed the latest guidelines on treatment of critical patients with neurosurgical and neurological pathologies, specifically the glycemic control in this category of patients.
{"title":"Glycemic Control in Neurological Intensive Care Unit Patients","authors":"K. Krylov, I. Savin, S. Sviridov, I. Vedenina, M. Petrova, A. Vorobyev, M. Rubanes","doi":"10.17816/clinutr60533","DOIUrl":"https://doi.org/10.17816/clinutr60533","url":null,"abstract":"Critically ill patients often develop hyperglycemia because of the metabolic response to trauma and stress. In response to any form of damage to the organism, it reacts by increasing its own glucose production which subsequently causes hyperglycemia. This adaptive reaction of the organism is directed to aid in the rapid restoration after the damage. Therefore, glucose is an indispensable substrate in the critically ill which aids the reparation process. Severe and persistent hyperglycemia is associated with unfavorable outcomes and is considered to be an independent predictor of in-hospital mortality. The discussion remains on whether hyperglycemia is just a marker of increased stress which makes it a surrogate indicator of disease severity or if it is the reason for the unfavorable outcome. A few years ago, several published articles suggested that a tight glycemic control within the normal range improves treatment outcome. Over time, researchers have changed their point of view and currently there is a discussion on this matter in the scientific literatures. At the same time, the question of what glycemic level should be maintained for patients in the Neurological Intensive Care Unit is a matter of discussion. In this review, the authors analyzed the latest guidelines on treatment of critical patients with neurosurgical and neurological pathologies, specifically the glycemic control in this category of patients.","PeriodicalId":92235,"journal":{"name":"Journal of clinical nutrition and metabolism","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78709711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Kobelkova, Dmitriy B. Nikitujk, R. M. Radzhabkadiev, K. Vybornaya, Semen V. Lavrinenko, M. M. Semenov
Nutrition plays a key role in achieving high professional results and maintaining the health of athletes. Terms in the nutrition of athletes are interpreted in different ways. In the Russian Federation, there are normative act regulating definitions of athletes' nutrition, specialized foodstuffs and biologically active food additives for athletes, and parameters of diets. Uniformity in the use of terminology will lead to uniqueness and accuracy of descriptions and analysis of research results, as well as an understanding of recommendations in the field of nutrition of athletes.
{"title":"Regulatory framework in sports nutrition in the Russian Federation (review)","authors":"I. Kobelkova, Dmitriy B. Nikitujk, R. M. Radzhabkadiev, K. Vybornaya, Semen V. Lavrinenko, M. M. Semenov","doi":"10.17816/CLINUTR50227","DOIUrl":"https://doi.org/10.17816/CLINUTR50227","url":null,"abstract":"Nutrition plays a key role in achieving high professional results and maintaining the health of athletes. Terms in the nutrition of athletes are interpreted in different ways. In the Russian Federation, there are normative act regulating definitions of athletes' nutrition, specialized foodstuffs and biologically active food additives for athletes, and parameters of diets. Uniformity in the use of terminology will lead to uniqueness and accuracy of descriptions and analysis of research results, as well as an understanding of recommendations in the field of nutrition of athletes.","PeriodicalId":92235,"journal":{"name":"Journal of clinical nutrition and metabolism","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83561148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ekhard E Ziegler, Winston Wk Koo, Steven E Nelson, Janice M Jeter
Objective: A range of doses of supplemental vitamin D has been shown to be effective in preventing rickets in breastfed infants, but the effect of different doses of vitamin D on bone metabolism and mineral content has not been delineated.
Methods: In a randomized trial, breastfed infants received from 2 to 9 months daily supplements of vitamin D in doses of 200 IU/d, 400 IU/d, 600 IU/d or 800 IU/d. Measures of bone metabolism (plasma) were determined periodically and bone mineral content (DXA) was determined at study entry and at the end of winter when infants were 5.5 to 9 months old. The main findings have been reported; here we report findings related to bone metabolism.
Results: There were no consistent meaningful effects of vitamin D dose on markers of bone metabolism. Some markers showed changes with age. Bone mineral content increased with age but showed no effect of vitamin D dose.
Conclusion: Vitamin D in daily doses from 200 IU/d to 800 IU/d had no measurable effect on bone mineral content or bone metabolism of breastfed infants.
{"title":"Lack of Effect of Graded Doses of Vitamin D on Bone Metabolism of Breastfed Infants.","authors":"Ekhard E Ziegler, Winston Wk Koo, Steven E Nelson, Janice M Jeter","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>A range of doses of supplemental vitamin D has been shown to be effective in preventing rickets in breastfed infants, but the effect of different doses of vitamin D on bone metabolism and mineral content has not been delineated.</p><p><strong>Methods: </strong>In a randomized trial, breastfed infants received from 2 to 9 months daily supplements of vitamin D in doses of 200 IU/d, 400 IU/d, 600 IU/d or 800 IU/d. Measures of bone metabolism (plasma) were determined periodically and bone mineral content (DXA) was determined at study entry and at the end of winter when infants were 5.5 to 9 months old. The main findings have been reported; here we report findings related to bone metabolism.</p><p><strong>Results: </strong>There were no consistent meaningful effects of vitamin D dose on markers of bone metabolism. Some markers showed changes with age. Bone mineral content increased with age but showed no effect of vitamin D dose.</p><p><strong>Conclusion: </strong>Vitamin D in daily doses from 200 IU/d to 800 IU/d had no measurable effect on bone mineral content or bone metabolism of breastfed infants.</p>","PeriodicalId":92235,"journal":{"name":"Journal of clinical nutrition and metabolism","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744599/pdf/nihms925602.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35702036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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