Pub Date : 2017-01-10DOI: 10.9734/bjmmr/2017/34107
A. T. Hasan, S. Hasan., Md-Anzam Ul-Islam, A. Trina, K. Deepa, Asaduzzaman
Aims: Study on pharmacotherapeutic pattern on cardiovascular patients is rarely done. Patient’s demography, drug usage and its clinical outcome are the basis for the assessment of cardiac treatment. The aim of this study to analyze the demography of patients of ischemic heart disease along with drug usage and current trends of practice in Bangladesh. Methods: This study was carried out over a period of two months at different units of NICVD, situated at Dhaka, Bangladesh. A structured questionnaire was prepared to collect necessary data from patients. Descriptive statistics was used to represent the data. Results: A total 363 discharged patients were interviewed followed by the verification of their discharge report and other medical documents to obtain necessary information. Out of 363 patients, frequency of male patients were high (74.66%, N= 271) than female patients (25.34%, Original N=92). There is a trends of ischemic heart disease development after 40 years of age and found significant in this study ( P< 0.05 ). In this study, 83.19% of total patients were above 40 years of age. We found a significant number of patients also had diabetes, asthma and chronic kidney disease. Treatment approach of ischemic heart disease includes pharmacotherapy, revascularization and percutaneous coronary intervention. 48 patients (13.22%) out of 363 went for revascularization and percutaneous coronary intervention was done to 25 patients (6.89%). The goal of Pharmacotherapy is to reduce blood cholesterol level, prevention of further platelet aggregation, reduction of angina and control of heart rate. In our study, we found that, statins, anti platelet and anti angina/anti ischemic drugs are core in the treatment of ischemic heart disease. Beta blocker, ACE inhibitor or ARB, CCB is commonly added to standard therapy to reduce mortality and for better therapeutic outcome. Among statins, the frequency of use of atorvastatin (87.93%), combination of clopidogrel and aspirin (73.90%) among anti platelet agents, combination of trimetazidine and nitroglycerine (61.56%) among anti angina/anti ischemic agents were highest. In our study, we found that bisoprolol was most commonly prescribed by the physicians among other beta blockers. Conclusion: The outcome of this study will be helpful for young professionals, general physicians and other professionals involved in the health care setting for the rational use of drugs and to formulate effective strategy for the management of ischemic heart disease.
{"title":"Pattern of Pharmacotherapy of Patients Having Ischemic Heart Disease at a Specialized Hospital in Dhaka, Bangladesh: A Survey Based Study on Patients Discharged from Hospital","authors":"A. T. Hasan, S. Hasan., Md-Anzam Ul-Islam, A. Trina, K. Deepa, Asaduzzaman","doi":"10.9734/bjmmr/2017/34107","DOIUrl":"https://doi.org/10.9734/bjmmr/2017/34107","url":null,"abstract":"Aims: Study on pharmacotherapeutic pattern on cardiovascular patients is rarely done. Patient’s demography, drug usage and its clinical outcome are the basis for the assessment of cardiac treatment. The aim of this study to analyze the demography of patients of ischemic heart disease along with drug usage and current trends of practice in Bangladesh. Methods: This study was carried out over a period of two months at different units of NICVD, situated at Dhaka, Bangladesh. A structured questionnaire was prepared to collect necessary data from patients. Descriptive statistics was used to represent the data. Results: A total 363 discharged patients were interviewed followed by the verification of their discharge report and other medical documents to obtain necessary information. Out of 363 patients, frequency of male patients were high (74.66%, N= 271) than female patients (25.34%, Original N=92). There is a trends of ischemic heart disease development after 40 years of age and found significant in this study ( P< 0.05 ). In this study, 83.19% of total patients were above 40 years of age. We found a significant number of patients also had diabetes, asthma and chronic kidney disease. Treatment approach of ischemic heart disease includes pharmacotherapy, revascularization and percutaneous coronary intervention. 48 patients (13.22%) out of 363 went for revascularization and percutaneous coronary intervention was done to 25 patients (6.89%). The goal of Pharmacotherapy is to reduce blood cholesterol level, prevention of further platelet aggregation, reduction of angina and control of heart rate. In our study, we found that, statins, anti platelet and anti angina/anti ischemic drugs are core in the treatment of ischemic heart disease. Beta blocker, ACE inhibitor or ARB, CCB is commonly added to standard therapy to reduce mortality and for better therapeutic outcome. Among statins, the frequency of use of atorvastatin (87.93%), combination of clopidogrel and aspirin (73.90%) among anti platelet agents, combination of trimetazidine and nitroglycerine (61.56%) among anti angina/anti ischemic agents were highest. In our study, we found that bisoprolol was most commonly prescribed by the physicians among other beta blockers. Conclusion: The outcome of this study will be helpful for young professionals, general physicians and other professionals involved in the health care setting for the rational use of drugs and to formulate effective strategy for the management of ischemic heart disease.","PeriodicalId":9249,"journal":{"name":"British journal of medicine and medical research","volume":"34 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89618043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-10DOI: 10.9734/BJMMR/2017/29257
T. Ashipa, A. Ofili
Introduction: Health workers have an important role to play in preventing mother-to-child transmission of HIV. This study assessed health workers’ practice of preventing mother-to-child transmission of HIV in Benin City, Edo State, Nigeria in conformity with the national guidelines. Methodology: The study Conclusion: The proportion of health workers with good, fair and poor practice of preventing mother-to-child transmission of HIV was 41.5%, 45.9% and 12.6%. The health workers identified several challenges during the course of the study. Addressing these challenges is crucial to achieving the goal of reducing mother-to-child transmission of HIV.
{"title":"Health Workers’ Practice of Preventing Mother-to-child Transmission of HIV in Benin City, Edo State, Nigeria","authors":"T. Ashipa, A. Ofili","doi":"10.9734/BJMMR/2017/29257","DOIUrl":"https://doi.org/10.9734/BJMMR/2017/29257","url":null,"abstract":"Introduction: Health workers have an important role to play in preventing mother-to-child transmission of HIV. This study assessed health workers’ practice of preventing mother-to-child transmission of HIV in Benin City, Edo State, Nigeria in conformity with the national guidelines. Methodology: The study Conclusion: The proportion of health workers with good, fair and poor practice of preventing mother-to-child transmission of HIV was 41.5%, 45.9% and 12.6%. The health workers identified several challenges during the course of the study. Addressing these challenges is crucial to achieving the goal of reducing mother-to-child transmission of HIV.","PeriodicalId":9249,"journal":{"name":"British journal of medicine and medical research","volume":"29 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75462786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-10DOI: 10.9734/BJMMR/2017/31176
Sujata Ghosh, Sushil Nayak, Saroj Roy
Background: PDPH (post dural puncture headache) is a common complication Methodology: In this randomised prospective single blind study, 200 patients undergoing Elective Caesarian Section were divided into two groups Q & W (n=100), each to receive subarachnoid block with Quinke needle (25G) and Whitcre Needle (25G) respectively. Assessment of the incidence of postdural puncture headache was done on the 1 st , 2 nd & 3 rd and 5 th postoperative days using a standard questionnaire. The presence, severity duration and nature and onset of headache was assessed. Results: The demographic profile was similar in both groups Q & W. The incidence of post dural puncture headache (PDPH) was greater with 25 G Quinke’s needle. The intensity and duration of PDPH was higher in group Q ie in whom Quinkes needle was used. Nausea and vomiting was also greater in group Q. Conclusion: There was a statistically significant decrease in the incidence of postdural puncture headache using conical tipped pencil point 25G Whitacre spinal needle. There was no statistical difference in the onset of PDPH and the accompanying symptoms with the use of Quinke or Whitacre needles.
{"title":"Assessment of Post Dural Puncture Headache in Patients Undergoing Caesarean Section: A Comparison between 25 G Quinke V/S Whitacre Needles","authors":"Sujata Ghosh, Sushil Nayak, Saroj Roy","doi":"10.9734/BJMMR/2017/31176","DOIUrl":"https://doi.org/10.9734/BJMMR/2017/31176","url":null,"abstract":"Background: PDPH (post dural puncture headache) is a common complication Methodology: In this randomised prospective single blind study, 200 patients undergoing Elective Caesarian Section were divided into two groups Q & W (n=100), each to receive subarachnoid block with Quinke needle (25G) and Whitcre Needle (25G) respectively. Assessment of the incidence of postdural puncture headache was done on the 1 st , 2 nd & 3 rd and 5 th postoperative days using a standard questionnaire. The presence, severity duration and nature and onset of headache was assessed. Results: The demographic profile was similar in both groups Q & W. The incidence of post dural puncture headache (PDPH) was greater with 25 G Quinke’s needle. The intensity and duration of PDPH was higher in group Q ie in whom Quinkes needle was used. Nausea and vomiting was also greater in group Q. Conclusion: There was a statistically significant decrease in the incidence of postdural puncture headache using conical tipped pencil point 25G Whitacre spinal needle. There was no statistical difference in the onset of PDPH and the accompanying symptoms with the use of Quinke or Whitacre needles.","PeriodicalId":9249,"journal":{"name":"British journal of medicine and medical research","volume":"15 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78342356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-10DOI: 10.9734/BJMMR/2017/30300
S. Chatterjee, P. Bhattacharya, Manas Ghosh, A. Acharyya, Kaushik Ghosh
This single centre descriptive observational design study was undertaken in a tertiary referral centre of South Bengal, India in an attempt to assess the outcome of stroke according to various risk factors and Glasgow coma scale at the time of admission. A better outcome was considered as Glasgow outcome scale score of 4 and 5 while poor outcome was considered as Glasgow outcome scale score of 3 or less.
{"title":"A Priliminary Study on In-hospital Outcome of Stroke in a Tertiary Centre of South Bengal, India","authors":"S. Chatterjee, P. Bhattacharya, Manas Ghosh, A. Acharyya, Kaushik Ghosh","doi":"10.9734/BJMMR/2017/30300","DOIUrl":"https://doi.org/10.9734/BJMMR/2017/30300","url":null,"abstract":"This single centre descriptive observational design study was undertaken in a tertiary referral centre of South Bengal, India in an attempt to assess the outcome of stroke according to various risk factors and Glasgow coma scale at the time of admission. A better outcome was considered as Glasgow outcome scale score of 4 and 5 while poor outcome was considered as Glasgow outcome scale score of 3 or less.","PeriodicalId":9249,"journal":{"name":"British journal of medicine and medical research","volume":"7 1","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72911460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-10DOI: 10.9734/bjmmr/2017/32971
K. Sujatha, V. Thyagaraj
Aims: This study was done to analyze the local pattern of poisoning, clinical presentation, management practices, complications and the outcome of various poisonings. Methods: It was a prospective observational study conducted over two years, from October 2013 to September 2015, at M.S.Ramaiah Medical College and Hospitals, Bangalore. It included 250 patients who presented with history of acute poisoning. Data was analyzed using SPSS version 16. Results: The mean age of the study subjects was 28.5 years. There were 126 (50.4%) males and 124 (49.6%) females. Majority of the patients were literate (n=229; 91.6%). About one third of the patients were unemployed (n=73; 29.2%) and more than half were married (n=141; 56.4%). Considering the socio economic status, 116 (55.24%) patients were from upper middle class II in urban areas, as compared to 40 (100%) patients from upper class I in rural areas using appropriate socioeconomic scales. Organophosphorus compound was the most common poison involved (n=72, 28.8%). There were 40 (16%) cases of aluminum phosphide poisoning. A total of 203 Original Research Article Sujatha and Thyagaraj; BJMMR, 21(2): 1-10, 2017; Article no.BJMMR.32971 2 (81.2%) patients sought medical help within an hour of poisoning. Complications encountered were ventilator associated pneumonia (n=5; 2%), renal failure (n=13; 5.2%) and hepatic failure (n=4; 1.6%). Majority of them recovered (n=229; 91.6%) and 13 (5.2%) patients died. Conclusion: The study subjects were relatively young, came from upper middle class nuclear families and were literate. Organophosphorus was the most common cause of poisoning. Most patients received emergency care within one hour of poisoning and mortality was low. A large majority also had underlying psychiatric illness. These conclusions may hold true to areas similar in socioeconomic conditions as ours in India.
目的:分析各种中毒的局部类型、临床表现、处理方法、并发症及转归。方法:这是一项前瞻性观察研究，于2013年10月至2015年9月在班加罗尔M.S.Ramaiah医学院和医院进行了两年多的研究。其中包括250例有急性中毒史的患者。数据分析使用SPSS version 16。结果:研究对象平均年龄28.5岁。男性126例(50.4%)，女性124例(49.6%)。大多数患者识字(n=229;91.6%)。约三分之一的患者失业(n=73;29.2%)，半数以上已婚(n=141;56.4%)。考虑社会经济地位，城市中上阶层116例(55.24%)，农村中上阶层40例(100%)。有机磷化合物是最常见的毒物(n=72, 28.8%)。磷化铝中毒40例(16%)。共有203篇原创研究文章Sujatha and Thyagaraj;地球物理学报，21(2):1-10,2017;文章no.BJMMR。32971.2(81.2%)患者在中毒后一小时内就医。并发症包括呼吸机相关性肺炎(n=5;2%)，肾功能衰竭(n=13;5.2%)和肝功能衰竭(n=4;1.6%)。大多数患者康复(n=229;91.6%)，死亡13例(5.2%)。结论:研究对象相对年轻，来自中上层核心家庭，有文化。有机磷是最常见的中毒原因。大多数病人在中毒后一小时内得到急救，死亡率很低。大多数人还患有潜在的精神疾病。这些结论可能适用于社会经济条件与印度相似的地区。
{"title":"A Clinical and Demographic Profile of Acute Poisoning in Adults: A Two Year Experience from a Tertiary Care Centre in Bangalore, India","authors":"K. Sujatha, V. Thyagaraj","doi":"10.9734/bjmmr/2017/32971","DOIUrl":"https://doi.org/10.9734/bjmmr/2017/32971","url":null,"abstract":"Aims: This study was done to analyze the local pattern of poisoning, clinical presentation, management practices, complications and the outcome of various poisonings. Methods: It was a prospective observational study conducted over two years, from October 2013 to September 2015, at M.S.Ramaiah Medical College and Hospitals, Bangalore. It included 250 patients who presented with history of acute poisoning. Data was analyzed using SPSS version 16. Results: The mean age of the study subjects was 28.5 years. There were 126 (50.4%) males and 124 (49.6%) females. Majority of the patients were literate (n=229; 91.6%). About one third of the patients were unemployed (n=73; 29.2%) and more than half were married (n=141; 56.4%). Considering the socio economic status, 116 (55.24%) patients were from upper middle class II in urban areas, as compared to 40 (100%) patients from upper class I in rural areas using appropriate socioeconomic scales. Organophosphorus compound was the most common poison involved (n=72, 28.8%). There were 40 (16%) cases of aluminum phosphide poisoning. A total of 203 Original Research Article Sujatha and Thyagaraj; BJMMR, 21(2): 1-10, 2017; Article no.BJMMR.32971 2 (81.2%) patients sought medical help within an hour of poisoning. Complications encountered were ventilator associated pneumonia (n=5; 2%), renal failure (n=13; 5.2%) and hepatic failure (n=4; 1.6%). Majority of them recovered (n=229; 91.6%) and 13 (5.2%) patients died. Conclusion: The study subjects were relatively young, came from upper middle class nuclear families and were literate. Organophosphorus was the most common cause of poisoning. Most patients received emergency care within one hour of poisoning and mortality was low. A large majority also had underlying psychiatric illness. These conclusions may hold true to areas similar in socioeconomic conditions as ours in India.","PeriodicalId":9249,"journal":{"name":"British journal of medicine and medical research","volume":"10 1","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74417612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-10DOI: 10.9734/bjmmr/2017/33482
A. Ghamdi, Naif N Alshahrani, F. Alenzi
Background: Patellofemoral pain syndrome (PFPS) refers to anterior or retropatellar pain in knees. It is amongst the widespread and commonly known knee disorders seen in orthopaedic clinics, especially in young adult. The majority of patients who have are initially treated non operatively and many non operative imitative are successful wherein physical exercise remains the basic approach to deal with the ailment. Amongst various physical therapies used; open kinetic chain exercises (OKCE) and closed kinetic chain exercises (CKCE) have gained prominence. Aim: The purpose of this study was to investigate the efficacy of closed versus open kinetic chain exercises in Saudi patients with PFPS, and to determine whether any of two programs offer any advantages over the other one. Original Research Article Al Ghamdi et al.; BJMMR, 21(3): 1-8, 2017; Article no.BJMMR.33482 2 Methodology: Forty male subjects with PFPS, were randomly assigned into two equal groups, each one consisted of 20 subjects, their age ranged between (20-40) years. Group 1; (28.20 ± 5.39) years, performed only closed kinetic chain exercises (CKCE). Group 2; (28.55 ± 8.00) years, performed only open kinetic chain exercises (OKCE). Pain intensity, patellofemoral scoring scale, isometric knee muscle strength, and patellar tendon muscle torque were measured before and after 6-weeks of treatment program. Results: Statistical analysis showed that both CKCE and OKCE have a significant effect in reduction of pain intensity, increased isometric knee muscle force, and the patellar tendon muscle torque. Results also showed that CKCE has more effective results than OKCE. Conclusion: This study indicates that both CKCE and OKCE could be used in treatment of
背景:髌股疼痛综合征(PFPS)是指膝关节的髌前或髌后疼痛。它是在骨科诊所中普遍存在的膝关节疾病之一，尤其是在年轻人中。大多数患者最初接受非手术治疗，许多非手术治疗是成功的，其中体育锻炼仍然是治疗疾病的基本方法。在使用的各种物理疗法中;开放式运动链练习(OKCE)和封闭式运动链练习(CKCE)得到了突出。目的:本研究的目的是调查封闭与开放动力链运动对沙特PFPS患者的疗效，并确定两种方案中是否有任何一种方案比另一种方案更有优势。Al Ghamdi et Al .;地球物理学报，21(3):1-8,2017;文章no.BJMMR。方法:40例男性PFPS患者随机分为两组，每组20例，年龄在20-40岁之间。组1;(28.20±5.39)岁，仅进行闭合动力链运动(CKCE)。组2;(28.55±8.00)岁，只进行开放式动力链运动(OKCE)。在治疗前和治疗后6周测量疼痛强度、髌骨评分量表、膝关节肌肉力量和髌骨肌腱肌肉扭矩。结果:统计分析显示，CKCE和OKCE在减轻疼痛强度、增加膝关节等距肌力和髌骨肌腱肌扭矩方面均有显著效果。结果还表明，CKCE比OKCE效果更好。结论:本研究提示CKCE和OKCE均可用于治疗
{"title":"Effectiveness of Exercise Protocols in Treatment of Patellofemoral Pain Syndrome: A Prospective Comparative Study","authors":"A. Ghamdi, Naif N Alshahrani, F. Alenzi","doi":"10.9734/bjmmr/2017/33482","DOIUrl":"https://doi.org/10.9734/bjmmr/2017/33482","url":null,"abstract":"Background: Patellofemoral pain syndrome (PFPS) refers to anterior or retropatellar pain in knees. It is amongst the widespread and commonly known knee disorders seen in orthopaedic clinics, especially in young adult. The majority of patients who have are initially treated non operatively and many non operative imitative are successful wherein physical exercise remains the basic approach to deal with the ailment. Amongst various physical therapies used; open kinetic chain exercises (OKCE) and closed kinetic chain exercises (CKCE) have gained prominence. Aim: The purpose of this study was to investigate the efficacy of closed versus open kinetic chain exercises in Saudi patients with PFPS, and to determine whether any of two programs offer any advantages over the other one. Original Research Article Al Ghamdi et al.; BJMMR, 21(3): 1-8, 2017; Article no.BJMMR.33482 2 Methodology: Forty male subjects with PFPS, were randomly assigned into two equal groups, each one consisted of 20 subjects, their age ranged between (20-40) years. Group 1; (28.20 ± 5.39) years, performed only closed kinetic chain exercises (CKCE). Group 2; (28.55 ± 8.00) years, performed only open kinetic chain exercises (OKCE). Pain intensity, patellofemoral scoring scale, isometric knee muscle strength, and patellar tendon muscle torque were measured before and after 6-weeks of treatment program. Results: Statistical analysis showed that both CKCE and OKCE have a significant effect in reduction of pain intensity, increased isometric knee muscle force, and the patellar tendon muscle torque. Results also showed that CKCE has more effective results than OKCE. Conclusion: This study indicates that both CKCE and OKCE could be used in treatment of","PeriodicalId":9249,"journal":{"name":"British journal of medicine and medical research","volume":"4 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85009336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-10DOI: 10.9734/bjmmr/2017/34207
P. Shallie, Olugbenga Olayinka, H. Akpan, O. Otulana, O. Alese, B. Babatunde, Damilola Talabi, O. Shallie
Aim: This study investigated the potential neuro-therapeutic effect of Flaxseed oil on the striatum of Rotenone mice model of Parkinson’ diseases’ Study Design: Fifty-six adult male and female mice ( Mus musculus) weighing between 23.9-26.3 grams were used for this study. The mice were randomly placed into four groups of fourteen mice each made up of equal number of male and female: A (Control; mice pellets), B (Rotenone 3 mg/kg, IP), C (Rotenone + Flaxseed oil 0.3 ml orally), and D (0.3 ml Flaxseed + Rotenone). Methodology: The brain were excised, weighed and appropriate sections taken and processed histology and stained with H&E and Nissl stains and immuno-cytochemically with GFAP. Results: The results showed significant (P<0.05) reduction in the neuronal cell count, body and relative brain to body weight, which were increased by flaxseed oil treatments. Rotenone induced neural and striatal bundle degeneration which were ameliorated by flaxseed oil treatment. Conclusion: In conclusion, the reduction in weight and neuronal derangements associated with rotenone induced Parkinson’s disease in this study were reduced or alleviated as a consequence of the treatment with flaxseed oil, and hence flaxseed oil could be considered as a potential therapeutic candidate in the management of Parkinson's disease.
{"title":"Potential Neuro-therapeutic Effect of Flaxseed Oil on the Striatum of Rotenone Mice Model of Parkinson’ Diseases","authors":"P. Shallie, Olugbenga Olayinka, H. Akpan, O. Otulana, O. Alese, B. Babatunde, Damilola Talabi, O. Shallie","doi":"10.9734/bjmmr/2017/34207","DOIUrl":"https://doi.org/10.9734/bjmmr/2017/34207","url":null,"abstract":"Aim: This study investigated the potential neuro-therapeutic effect of Flaxseed oil on the striatum of Rotenone mice model of Parkinson’ diseases’ Study Design: Fifty-six adult male and female mice ( Mus musculus) weighing between 23.9-26.3 grams were used for this study. The mice were randomly placed into four groups of fourteen mice each made up of equal number of male and female: A (Control; mice pellets), B (Rotenone 3 mg/kg, IP), C (Rotenone + Flaxseed oil 0.3 ml orally), and D (0.3 ml Flaxseed + Rotenone). Methodology: The brain were excised, weighed and appropriate sections taken and processed histology and stained with H&E and Nissl stains and immuno-cytochemically with GFAP. Results: The results showed significant (P<0.05) reduction in the neuronal cell count, body and relative brain to body weight, which were increased by flaxseed oil treatments. Rotenone induced neural and striatal bundle degeneration which were ameliorated by flaxseed oil treatment. Conclusion: In conclusion, the reduction in weight and neuronal derangements associated with rotenone induced Parkinson’s disease in this study were reduced or alleviated as a consequence of the treatment with flaxseed oil, and hence flaxseed oil could be considered as a potential therapeutic candidate in the management of Parkinson's disease.","PeriodicalId":9249,"journal":{"name":"British journal of medicine and medical research","volume":"24 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79486433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-10DOI: 10.9734/BJMMR/2017/33672
S. Alanazy, Turki Aldriweesh
In identical twins, they have strong special environmental, psychological and social relationships. Rhinoplasty is one of the most popular procedure and in this group of the population carries distinct consideration regarding the evaluation of the behavior of each of them, dysmorphia, expectations, motivation, operative timing, phenotype identities, and result. The rhinoplasty surgeon deals with them as a two-part unit. The aim of this review is to elaborate the difficulty of rhinoplasty in identical twins from the first visit until post-operative period.
{"title":"Identical Twins Rhinoplasty; Twice the Challenge","authors":"S. Alanazy, Turki Aldriweesh","doi":"10.9734/BJMMR/2017/33672","DOIUrl":"https://doi.org/10.9734/BJMMR/2017/33672","url":null,"abstract":"In identical twins, they have strong special environmental, psychological and social relationships. Rhinoplasty is one of the most popular procedure and in this group of the population carries distinct consideration regarding the evaluation of the behavior of each of them, dysmorphia, expectations, motivation, operative timing, phenotype identities, and result. The rhinoplasty surgeon deals with them as a two-part unit. The aim of this review is to elaborate the difficulty of rhinoplasty in identical twins from the first visit until post-operative period.","PeriodicalId":9249,"journal":{"name":"British journal of medicine and medical research","volume":"1 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84057605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The National Center of Oncology in Nouakchott is equipped with a linear accelerator which provides two energies in photon regime 6 MV and 18 MV. The basic dosimetric data required for quality of operation, in the clinical routine of the accelerator for photon beams are percentage depth dose (PDD) curves and beam profile (BP) curves. The aim of this work is to measure the percentage depth dose (PDD) and beam/dose profile (BP) for 6 MV and 18 MV photon beams for different field sizes and for different Skin-Source-Distance (SSD), and to compare the measured results with the results calculated by Treatment Planning Systems (TPS). The measured results of (PDD) and (BF) are consistent with those calculated by TPS, which allows us to conclude that the linear accelerator at oncology Center in Nouakchott is in good condition. Other Parameters: (energy, (SSD) and field sizes) have been also studied in this work, in order to perform a comprehensive quality study for this accelerator a unique oncology at Mauritania.
{"title":"Preliminary Results of Quality Control for Linear Accelerator at Oncology Center in Nouakchott","authors":"Ould El-Mouna, O. Moussa, Choukri Abdelmajid, Ghassoun Jilali, Hakam Keltoum, Semghouli Slimane","doi":"10.9734/bjmmr/2017/33918","DOIUrl":"https://doi.org/10.9734/bjmmr/2017/33918","url":null,"abstract":"The National Center of Oncology in Nouakchott is equipped with a linear accelerator which provides two energies in photon regime 6 MV and 18 MV. The basic dosimetric data required for quality of operation, in the clinical routine of the accelerator for photon beams are percentage depth dose (PDD) curves and beam profile (BP) curves. The aim of this work is to measure the percentage depth dose (PDD) and beam/dose profile (BP) for 6 MV and 18 MV photon beams for different field sizes and for different Skin-Source-Distance (SSD), and to compare the measured results with the results calculated by Treatment Planning Systems (TPS). The measured results of (PDD) and (BF) are consistent with those calculated by TPS, which allows us to conclude that the linear accelerator at oncology Center in Nouakchott is in good condition. Other Parameters: (energy, (SSD) and field sizes) have been also studied in this work, in order to perform a comprehensive quality study for this accelerator a unique oncology at Mauritania.","PeriodicalId":9249,"journal":{"name":"British journal of medicine and medical research","volume":"4 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80840984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-10DOI: 10.9734/bjmmr/2017/32090
A. Iwu, C. Duru, K. Uwakwe, K. Diwe, I. Merenu, H. Chineke, U. Madubueze, C. Abejegah, Emmanuel N. Ndukwu, I. Ohale
Background: HIV/AIDS is a chronic disease on long term treatment and as such it is important that the quality of care meets the patient’s expectations and satisfaction which will consequently encourage treatment adherence that is associated with better HIV management, care and outcomes. Original Research Article Iwu et al.; BJMMR, 20(4): 1-14, 2017; Article no.BJMMR.32090 2 Objective: To determine the levels of patients’ perception and satisfaction of the quality of HIV care services and the sociodemographic determinants associated with the level of satisfaction. Methods: This is a descriptive cross sectional study and respondents were selected using a simple random sampling technique. Data was collected using a pretested semi structured questionnaire. Descriptive analyses were done with frequencies and summary statistics. Chi square statistics were computed to determine significant associations and multiple logistic regression to determine predictors of satisfaction. P value was set at 0.05 significant level. Results: The results revealed that the majority of the respondents (65.6%) perceived that the quality of service rendered was good and were satisfied overall (79.5%) with the services rendered in the HIV clinic of the hospital. It further revealed that the patients overall satisfaction were significantly associated with the following socio-demographic characteristics; religion (p<0.000), marital status (p<0.000), educational level (p<0.000), occupation (p<0.000), centre of HIV diagnosis and treatment (p<0.000), place of residence (p<0.000), number of children (p<0.000), number of people per household (p<0.000), living-in arrangements (p<0.000), and transport cost per visit (p=0.001). Conclusion: Certain HIV care service areas need improvement in spite of the good level of patients’ perception and overall satisfaction with the quality of HIV care services offered in the tertiary health institution, as this will further enhance the overall patients’ experience and satisfaction thereby increasing the certainty of better treatment adherence and retention in medical care.
{"title":"Patients’ Perception and Satisfaction with the Quality of HIV Care Services and Its Associated Socio-demographic Determinants in a Tertiary Care Hospital","authors":"A. Iwu, C. Duru, K. Uwakwe, K. Diwe, I. Merenu, H. Chineke, U. Madubueze, C. Abejegah, Emmanuel N. Ndukwu, I. Ohale","doi":"10.9734/bjmmr/2017/32090","DOIUrl":"https://doi.org/10.9734/bjmmr/2017/32090","url":null,"abstract":"Background: HIV/AIDS is a chronic disease on long term treatment and as such it is important that the quality of care meets the patient’s expectations and satisfaction which will consequently encourage treatment adherence that is associated with better HIV management, care and outcomes. Original Research Article Iwu et al.; BJMMR, 20(4): 1-14, 2017; Article no.BJMMR.32090 2 Objective: To determine the levels of patients’ perception and satisfaction of the quality of HIV care services and the sociodemographic determinants associated with the level of satisfaction. Methods: This is a descriptive cross sectional study and respondents were selected using a simple random sampling technique. Data was collected using a pretested semi structured questionnaire. Descriptive analyses were done with frequencies and summary statistics. Chi square statistics were computed to determine significant associations and multiple logistic regression to determine predictors of satisfaction. P value was set at 0.05 significant level. Results: The results revealed that the majority of the respondents (65.6%) perceived that the quality of service rendered was good and were satisfied overall (79.5%) with the services rendered in the HIV clinic of the hospital. It further revealed that the patients overall satisfaction were significantly associated with the following socio-demographic characteristics; religion (p<0.000), marital status (p<0.000), educational level (p<0.000), occupation (p<0.000), centre of HIV diagnosis and treatment (p<0.000), place of residence (p<0.000), number of children (p<0.000), number of people per household (p<0.000), living-in arrangements (p<0.000), and transport cost per visit (p=0.001). Conclusion: Certain HIV care service areas need improvement in spite of the good level of patients’ perception and overall satisfaction with the quality of HIV care services offered in the tertiary health institution, as this will further enhance the overall patients’ experience and satisfaction thereby increasing the certainty of better treatment adherence and retention in medical care.","PeriodicalId":9249,"journal":{"name":"British journal of medicine and medical research","volume":"39 1","pages":"1-14"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80163097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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