Pub Date : 2017-01-10DOI: 10.9734/BJMMR/2017/32743
M. Tena-Suck, C. Sánchez-Garibay, Citlaltepelt Salinas-Lara
Background: Pleomorphic Malignant Fibrous histiocytoma (MFH) is a rare neoplasms of the soft tissue and bone composed of fibroblastic and histiocytic components with mitosis figures, nuclear pleomorphism and anaplasia. Case Presentation: We presented a rare case of MFH in 44 year old woman with history of systemic erythematosus lupus and seizures. Treated with prednisone. The cerebral TAC showed a temporal mass. Craniotomy was performed and the examination of the biopsy sample revealed a giant, pleomorphic and atypical cells. Immunohistochemical analysis showed positivity for vimentin, CD68, Fascin, lysosyme and MIB-1 labeling index of 20%. Pleomorphic malignant fibrous histiocytoma was diagnosed, with involvement of the overlying temporal lobe. We report a case of MFH of the left temporal in adult. Discussion: The neuroimaging and intra-operative opinion were of a meningioma. Histopathology, Case Study Tena-Suck et al.; BJMMR, 21(9): 1-8, 2017; Article no.BJMMR.32743 2 in conjunction with immunohistochemical evaluation and proliferation marker, confirmed the diagnosis. This is the firth case reported of PMFH associated to systemic lupus erythematous and different histological patterns.
{"title":"Intracranial Pleomorphic Malignant Fibrous Histiocytoma, Associated to Systemic Lupus Erythematous: A Case Report","authors":"M. Tena-Suck, C. Sánchez-Garibay, Citlaltepelt Salinas-Lara","doi":"10.9734/BJMMR/2017/32743","DOIUrl":"https://doi.org/10.9734/BJMMR/2017/32743","url":null,"abstract":"Background: Pleomorphic Malignant Fibrous histiocytoma (MFH) is a rare neoplasms of the soft tissue and bone composed of fibroblastic and histiocytic components with mitosis figures, nuclear pleomorphism and anaplasia. Case Presentation: We presented a rare case of MFH in 44 year old woman with history of systemic erythematosus lupus and seizures. Treated with prednisone. The cerebral TAC showed a temporal mass. Craniotomy was performed and the examination of the biopsy sample revealed a giant, pleomorphic and atypical cells. Immunohistochemical analysis showed positivity for vimentin, CD68, Fascin, lysosyme and MIB-1 labeling index of 20%. Pleomorphic malignant fibrous histiocytoma was diagnosed, with involvement of the overlying temporal lobe. We report a case of MFH of the left temporal in adult. Discussion: The neuroimaging and intra-operative opinion were of a meningioma. Histopathology, Case Study Tena-Suck et al.; BJMMR, 21(9): 1-8, 2017; Article no.BJMMR.32743 2 in conjunction with immunohistochemical evaluation and proliferation marker, confirmed the diagnosis. This is the firth case reported of PMFH associated to systemic lupus erythematous and different histological patterns.","PeriodicalId":9249,"journal":{"name":"British journal of medicine and medical research","volume":"262 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77682647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-10DOI: 10.9734/bjmmr/2017/32186
D. Odatuwa-Omagbemi, R. Enemudo, C. Otene, C. Elachi, E. Akpojevwe, N. Awunor, M. Okeke
Objective: To explore factors determining the level of satisfaction of surgical in-patients with services rendered at the Delta State University Teaching Hospital (DELSUTH), Oghara, Delta State, Nigeria. Methodology: A descriptive cross sectional study was carried out among 115 adult surgical in-patients using an interviewer administered structured questionnaire (Patient Satistaction Questionnaire Short Form-PSQ-18). Data analysis was done using SPSS version 17 software. Results: A hundred and fifteen respondents participated in this survey. The mean age of respondents was 40.9 ±16.0 years. Most respondents were male 62 (53.9%). Average overall Original Research Article satisfaction was 63.1%. Of the seven dimensions of patient satisfaction among respondents, financial sub-scale and time spent seeing doctor had the lowest satisfaction ratings of 30.4% and 47% respectively. Technical quality of care (82.6%) was one of the sub-scales patients were most satisfied with. It was observed that it was only with regards to the dimensions of satisfaction with communication, interpersonal aspect of care and satisfaction with access to care that any socio-demographic characteristic showed a significant association with the patient satisfaction. Conclusion: Although, many surgical in-patients were satisfied with the technical quality of care and interpersonal relationship with doctors, most of them find it difficult to pay hospital fees and feel they spend too much time in the process of seeing doctors and accessing other services. There is need for a possible downward review of our fees and efforts geared at shortening waiting time.
{"title":"Surgical in- Patient Satisfaction with Services Rendered in a Tertiary Health Facility in Delta State, Nigeria","authors":"D. Odatuwa-Omagbemi, R. Enemudo, C. Otene, C. Elachi, E. Akpojevwe, N. Awunor, M. Okeke","doi":"10.9734/bjmmr/2017/32186","DOIUrl":"https://doi.org/10.9734/bjmmr/2017/32186","url":null,"abstract":"Objective: To explore factors determining the level of satisfaction of surgical in-patients with services rendered at the Delta State University Teaching Hospital (DELSUTH), Oghara, Delta State, Nigeria. Methodology: A descriptive cross sectional study was carried out among 115 adult surgical in-patients using an interviewer administered structured questionnaire (Patient Satistaction Questionnaire Short Form-PSQ-18). Data analysis was done using SPSS version 17 software. Results: A hundred and fifteen respondents participated in this survey. The mean age of respondents was 40.9 ±16.0 years. Most respondents were male 62 (53.9%). Average overall Original Research Article satisfaction was 63.1%. Of the seven dimensions of patient satisfaction among respondents, financial sub-scale and time spent seeing doctor had the lowest satisfaction ratings of 30.4% and 47% respectively. Technical quality of care (82.6%) was one of the sub-scales patients were most satisfied with. It was observed that it was only with regards to the dimensions of satisfaction with communication, interpersonal aspect of care and satisfaction with access to care that any socio-demographic characteristic showed a significant association with the patient satisfaction. Conclusion: Although, many surgical in-patients were satisfied with the technical quality of care and interpersonal relationship with doctors, most of them find it difficult to pay hospital fees and feel they spend too much time in the process of seeing doctors and accessing other services. There is need for a possible downward review of our fees and efforts geared at shortening waiting time.","PeriodicalId":9249,"journal":{"name":"British journal of medicine and medical research","volume":"6 1","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83469286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-10DOI: 10.9734/bjmmr/2017/33832
U. Adamu, A. Abdulahi, M. Aliyu, F. Gbate, O. Agboola, K. Edem, I. Umenze, I. Ibok
Background: Obesity is one of the commonest cardiovascular risk factor that affects blood pressure control, but there is lack of data regarding the prevalence of overweight and obesity in hypertensives and their relationship. The aim of this study is to determine the prevalence of obesity and its impact on blood pressure control amongst hypertensives in a rural hospital setting in NorthCentral Nigeria. Methodology: We recruited 414 hypertensives (204 men, 210 women; age range 21-84 years) adults with arterial hypertension. The blood pressure was measured and data on anthropometric indices were collected using a questionnaire. The weight and height was measured, used to calculate the body mass index and to classify the participants into obese and nonobese. Results: The mean age of the hypertensives was 53.09 ± 12.30 years. Out of the 414 participants, obesity occurred in 183 (44.2%) of the participants and more in those in the 45-54 years age range. Out of these, 93 (50.82%) had class I obesity, 55 (30.05%) class II obesity and class III obesity was found in 35 (19.13%) of the hypertensives. Blood pressure control was poor in 105 (57.4%) and 82 (35.5%) of hypertensives with and without obesity respectively. The BMI correlated with age r=-0.375 p=0.000, systolic blood pressure -0.181 p=0.014 and diastolic blood pressure r=0.439 p= 0.000. Conclusions: The prevalence of obesity is high in hypertensive individuals even in a rural hospital setting and blood pressure control is poor in those who are obese. Public health measures aimed at reducing obesity should be incorporated in the overall management of arterial hypertension.
{"title":"Prevalence of Obesity and Its Effect on Blood Pressure Control in Bida, North-Central Nigeria: A Hospital Based Cross-sectional Study","authors":"U. Adamu, A. Abdulahi, M. Aliyu, F. Gbate, O. Agboola, K. Edem, I. Umenze, I. Ibok","doi":"10.9734/bjmmr/2017/33832","DOIUrl":"https://doi.org/10.9734/bjmmr/2017/33832","url":null,"abstract":"Background: Obesity is one of the commonest cardiovascular risk factor that affects blood pressure control, but there is lack of data regarding the prevalence of overweight and obesity in hypertensives and their relationship. The aim of this study is to determine the prevalence of obesity and its impact on blood pressure control amongst hypertensives in a rural hospital setting in NorthCentral Nigeria. Methodology: We recruited 414 hypertensives (204 men, 210 women; age range 21-84 years) adults with arterial hypertension. The blood pressure was measured and data on anthropometric indices were collected using a questionnaire. The weight and height was measured, used to calculate the body mass index and to classify the participants into obese and nonobese. Results: The mean age of the hypertensives was 53.09 ± 12.30 years. Out of the 414 participants, obesity occurred in 183 (44.2%) of the participants and more in those in the 45-54 years age range. Out of these, 93 (50.82%) had class I obesity, 55 (30.05%) class II obesity and class III obesity was found in 35 (19.13%) of the hypertensives. Blood pressure control was poor in 105 (57.4%) and 82 (35.5%) of hypertensives with and without obesity respectively. The BMI correlated with age r=-0.375 p=0.000, systolic blood pressure -0.181 p=0.014 and diastolic blood pressure r=0.439 p= 0.000. Conclusions: The prevalence of obesity is high in hypertensive individuals even in a rural hospital setting and blood pressure control is poor in those who are obese. Public health measures aimed at reducing obesity should be incorporated in the overall management of arterial hypertension.","PeriodicalId":9249,"journal":{"name":"British journal of medicine and medical research","volume":"68 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88430727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-10DOI: 10.9734/bjmmr/2017/31940
N. Orazulike, P. Fiebai, P. Tabansi, B. Otaigbe, R. Ajayi
Aim: To evaluate the outcome of children born following Assisted Reproductive Technology in Port Harcourt, Nigeria. Study Design: A retrospective study. Place of Study: Department of Paediatrics, University of Port Harcourt Teaching Hospital, Port Harcourt. Methods: Fifty ART-conceived-children (subjects) and 50 spontaneously conceived children (controls) between 2004 and 2013 were studied. The subjects were recruited from the treatment records of The Bridge Clinic, Port Harcourt. Those who gave consent were invited to the paediatric Original Research Article Orazulike et al.; BJMMR, 20(1): 1-8, 2017; Article no.BJMMR.31940 2 clinic of the University of Port Harcourt Teaching Hospital (UPTH) between January 2014 and June 2014 where they were interviewed with a structured questionnaire. Data collected was collated and analysed with Epi Info Ver. 6.04d. Results: The mean gestational age at delivery (36.3 ± 3.1 versus 38.9 ± 1.2 weeks) and the mean birth weight (2.6 ± 0.8 versus 3.4 ± 0.5 kg) were significantly lower in the cases than controls. There was a higher incidence of congenital anomalies in the ART babies 17(34%) versus 0(0%) [OR 25.24, 95% CI: 3.25 53.19]. Admission into the Neonatal Intensive Care Unit (NICU) was also significantly higher in the ART babies, 15(30%) versus 3(6%) [OR 6.53, 95% CI: 6.23 30.90]. Conclusion: The children born from ART in Port Harcourt had more adverse outcome than spontaneously conceived children with respect to preterm birth, lower birth weight, neonatal admission and congenital anomalies. Patients should be adequately counseled on these outcomes before they embark on assisted conception.
目的:评估尼日利亚哈科特港辅助生殖技术后出生的儿童的结局。研究设计:回顾性研究。学习地点:哈科特港哈科特大学教学医院儿科学系。方法:选取2004 ~ 2013年50例人工受孕儿童(被试)和50例自然受孕儿童(对照组)为研究对象。受试者从哈科特港桥诊所的治疗记录中招募。那些给予同意的人被邀请阅读儿科原始研究文章Orazulike et al;生物医学工程学报，20(1):1-8,2017;文章no.BJMMR。在2014年1月至2014年6月期间，他们在哈科特港大学教学医院(UPTH) 31940诊所接受了结构化问卷调查。收集的数据用Epi Info Ver. 6.04 4d进行整理和分析。结果:患儿平均胎龄(36.3±3.1 vs 38.9±1.2周)和平均出生体重(2.6±0.8 vs 3.4±0.5 kg)明显低于对照组。ART婴儿先天性异常的发生率高于17(34%)比0(0%)[OR 25.24, 95% CI: 3.25 53.19]。ART婴儿入住新生儿重症监护病房(NICU)的比例也显著高于ART婴儿，15(30%)比3(6%)[OR 6.53, 95% CI: 6.23 30.90]。结论:在哈科特港通过抗逆转录病毒技术出生的儿童在早产、低出生体重、新生儿入院和先天性异常方面比自然受孕的儿童有更多的不良后果。在进行辅助受孕之前，患者应充分了解这些结果。
{"title":"Outcome and Congenital Anomalies in Children Born after Assisted Reproductive Technology in Port Harcourt","authors":"N. Orazulike, P. Fiebai, P. Tabansi, B. Otaigbe, R. Ajayi","doi":"10.9734/bjmmr/2017/31940","DOIUrl":"https://doi.org/10.9734/bjmmr/2017/31940","url":null,"abstract":"Aim: To evaluate the outcome of children born following Assisted Reproductive Technology in Port Harcourt, Nigeria. Study Design: A retrospective study. Place of Study: Department of Paediatrics, University of Port Harcourt Teaching Hospital, Port Harcourt. Methods: Fifty ART-conceived-children (subjects) and 50 spontaneously conceived children (controls) between 2004 and 2013 were studied. The subjects were recruited from the treatment records of The Bridge Clinic, Port Harcourt. Those who gave consent were invited to the paediatric Original Research Article Orazulike et al.; BJMMR, 20(1): 1-8, 2017; Article no.BJMMR.31940 2 clinic of the University of Port Harcourt Teaching Hospital (UPTH) between January 2014 and June 2014 where they were interviewed with a structured questionnaire. Data collected was collated and analysed with Epi Info Ver. 6.04d. Results: The mean gestational age at delivery (36.3 ± 3.1 versus 38.9 ± 1.2 weeks) and the mean birth weight (2.6 ± 0.8 versus 3.4 ± 0.5 kg) were significantly lower in the cases than controls. There was a higher incidence of congenital anomalies in the ART babies 17(34%) versus 0(0%) [OR 25.24, 95% CI: 3.25 53.19]. Admission into the Neonatal Intensive Care Unit (NICU) was also significantly higher in the ART babies, 15(30%) versus 3(6%) [OR 6.53, 95% CI: 6.23 30.90]. Conclusion: The children born from ART in Port Harcourt had more adverse outcome than spontaneously conceived children with respect to preterm birth, lower birth weight, neonatal admission and congenital anomalies. Patients should be adequately counseled on these outcomes before they embark on assisted conception.","PeriodicalId":9249,"journal":{"name":"British journal of medicine and medical research","volume":"16 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77154232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-10DOI: 10.9734/BJMMR/2017/30384
A. Nagarajappa, Ankit Dhimole, S. Asrani, A. Agarwal, Ankur Kakkad
The calcifying odontogenic cyst was first described by Gorlin et al in 1962 and has been referred to as “Gorlin’s cyst” or “Calcifying ghost cell odontogenic cyst”. The lesion has cystic as well as tumor-like elements and was termed “calcifying cystic odontogenic tumor” (CCOT) by the World Health Organization (WHO) in 2005. The CCOT is benign; more commonly affects the anterior aspect of jaws and is without gender dominance. Knowledge of its clinical, radiographic, and pathological features is necessary to arrive at a proper diagnosis and management because it resembles other forms of pathology. Diagnosis relies mainly on radiographic features and the histologic presence of ghost cells within the epithelium. We report here a classic case of a CCOT in a 28 year old female.
{"title":"Calcifying Cystic Odontogenic Tumor: A Diagnostic Challenge","authors":"A. Nagarajappa, Ankit Dhimole, S. Asrani, A. Agarwal, Ankur Kakkad","doi":"10.9734/BJMMR/2017/30384","DOIUrl":"https://doi.org/10.9734/BJMMR/2017/30384","url":null,"abstract":"The calcifying odontogenic cyst was first described by Gorlin et al in 1962 and has been referred to as “Gorlin’s cyst” or “Calcifying ghost cell odontogenic cyst”. The lesion has cystic as well as tumor-like elements and was termed “calcifying cystic odontogenic tumor” (CCOT) by the World Health Organization (WHO) in 2005. The CCOT is benign; more commonly affects the anterior aspect of jaws and is without gender dominance. Knowledge of its clinical, radiographic, and pathological features is necessary to arrive at a proper diagnosis and management because it resembles other forms of pathology. Diagnosis relies mainly on radiographic features and the histologic presence of ghost cells within the epithelium. We report here a classic case of a CCOT in a 28 year old female.","PeriodicalId":9249,"journal":{"name":"British journal of medicine and medical research","volume":"11 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86964419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-10DOI: 10.9734/BJMMR/2017/31529
M. Qadire, Murad Alkhalaileh
Aims: This study aims to assess Jordanian public satisfaction with healthcare services. Study Design: A descriptive cross-sectional survey design was used. Place and Duration of Study: Data were collected from 571 Jordanian participants in the period between June 2016 and November 2016. Methodology: Participants were Jordanians 18 or older, and visited a hospital (tertiary healthcare centres) in the last three weeks were conveniently recruited. A study questionnaire was constructed by the researcher to assess public satisfaction; it was grounded on previous literature and the author’s personal experience. The satisfaction measurement consisted of 30 variables. Results: The mean age of participants was 34.7 (SD 13.6 years) and most of them were females. Most of the participants (58.8%) were not satisfied and the mean total satisfaction score was low at 159.6 (SD 54.9). Participants who were more educated lived in the southern region, and regularly visited healthcare settings reported lower (not satisfied) satisfaction scores. Conclusion: This study demonstrated that higher proportion of Jordanian patients were not satisfied with the healthcare services provided. The determinants of patients’ satisfaction were not completely dependent on the actual medical or nursing care. The identified determinants of patient satisfaction should inform satisfaction indicators when developing satisfaction measurement tools, whether in clinical or research settings.
{"title":"Determinants of Public Satisfaction and Perception of National Healthcare Services Availability in Jordan: A Patient Survey","authors":"M. Qadire, Murad Alkhalaileh","doi":"10.9734/BJMMR/2017/31529","DOIUrl":"https://doi.org/10.9734/BJMMR/2017/31529","url":null,"abstract":"Aims: This study aims to assess Jordanian public satisfaction with healthcare services. Study Design: A descriptive cross-sectional survey design was used. Place and Duration of Study: Data were collected from 571 Jordanian participants in the period between June 2016 and November 2016. Methodology: Participants were Jordanians 18 or older, and visited a hospital (tertiary healthcare centres) in the last three weeks were conveniently recruited. A study questionnaire was constructed by the researcher to assess public satisfaction; it was grounded on previous literature and the author’s personal experience. The satisfaction measurement consisted of 30 variables. Results: The mean age of participants was 34.7 (SD 13.6 years) and most of them were females. Most of the participants (58.8%) were not satisfied and the mean total satisfaction score was low at 159.6 (SD 54.9). Participants who were more educated lived in the southern region, and regularly visited healthcare settings reported lower (not satisfied) satisfaction scores. Conclusion: This study demonstrated that higher proportion of Jordanian patients were not satisfied with the healthcare services provided. The determinants of patients’ satisfaction were not completely dependent on the actual medical or nursing care. The identified determinants of patient satisfaction should inform satisfaction indicators when developing satisfaction measurement tools, whether in clinical or research settings.","PeriodicalId":9249,"journal":{"name":"British journal of medicine and medical research","volume":"51 1","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86981131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-10DOI: 10.9734/bjmmr/2017/32947
Cassiane Merigo do Nascimento, F. A. Felipetti, A. L. Rangel, Danielle Shima Luize, M. Bonfleur, S. Balbo, C. Nassar, P. Nassar
Department of Biosciences and Health, University of State of West of Parana (UNIOESTE), Rua Universitária, 1619 – Jd., Universitário, Cascavel, Parana, Brazil. Department of Pathology, University of State of West of Paraná (UNIOESTE), Rua Universitária, 1619 – Jd., Universitário, Cascavel, Paraná, Brazil. Department of Periodontology, Dental School, Cascavel, University of State of West of Paraná (UNIOESTE), Rua Universitária, 1619 – Jd., Universitário, Cascavel, Paraná, Brazil. Department of Physiology, University of State of West of Paraná (UNIOESTE), Rua Universitária, 1619 – Jd., Universitário, Cascavel, Paraná, Brazil.
{"title":"Obesity Effects on Bone Femur Tissue of Animals Subjected to Obesity through High-fat Diet","authors":"Cassiane Merigo do Nascimento, F. A. Felipetti, A. L. Rangel, Danielle Shima Luize, M. Bonfleur, S. Balbo, C. Nassar, P. Nassar","doi":"10.9734/bjmmr/2017/32947","DOIUrl":"https://doi.org/10.9734/bjmmr/2017/32947","url":null,"abstract":"Department of Biosciences and Health, University of State of West of Parana (UNIOESTE), Rua Universitária, 1619 – Jd., Universitário, Cascavel, Parana, Brazil. Department of Pathology, University of State of West of Paraná (UNIOESTE), Rua Universitária, 1619 – Jd., Universitário, Cascavel, Paraná, Brazil. Department of Periodontology, Dental School, Cascavel, University of State of West of Paraná (UNIOESTE), Rua Universitária, 1619 – Jd., Universitário, Cascavel, Paraná, Brazil. Department of Physiology, University of State of West of Paraná (UNIOESTE), Rua Universitária, 1619 – Jd., Universitário, Cascavel, Paraná, Brazil.","PeriodicalId":9249,"journal":{"name":"British journal of medicine and medical research","volume":"30 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88951275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-10DOI: 10.9734/BJMMR/2017/32921
V. Odogu, I. Chukwuka, N. Chinawa
Aim: Waardenburg syndrome is a very rare condition, inherited autosomally with genetic heterogeneity and characterized by deafness, hair discoloration, iris discoloration and eyelid changes. Case Report: We report a case of an 8 year old female child with a history of a striking difference between the eyes since birth. Ocular examination revealed slightly widened medial canthal distances and hypertelorism. There was a lateral displacement of the right inner canthi [Dystopia Canthorum]. The Iris was hypopigmented and bluish in colour in the right eye, whilst the left Iris was brown and darkly pigmented. Discussion: The diagnosis of WS is considered if there are 2 major or 1 major and 2 minor criteria Case Report according to Waardenburg consortium. Our patient had 2 major criteria viz disturbances of the iris and dystopia canthorum. Waardenburg syndrome is sub classified into 4 types. The management of Waardenburg's syndrome, comprises early detection and referral to the appropriate unit including audiology, correction for refractive error and use of cosmetic contact lenses. Conclusion: Waardenburg syndrome is a rare disease. In all su impairment, severe musculoskeletal contractures and Hirschsprungs disease should be ruled out
{"title":"Waardenburg Syndrome in an 8 Year Old African Child: Case Report","authors":"V. Odogu, I. Chukwuka, N. Chinawa","doi":"10.9734/BJMMR/2017/32921","DOIUrl":"https://doi.org/10.9734/BJMMR/2017/32921","url":null,"abstract":"Aim: Waardenburg syndrome is a very rare condition, inherited autosomally with genetic heterogeneity and characterized by deafness, hair discoloration, iris discoloration and eyelid changes. Case Report: We report a case of an 8 year old female child with a history of a striking difference between the eyes since birth. Ocular examination revealed slightly widened medial canthal distances and hypertelorism. There was a lateral displacement of the right inner canthi [Dystopia Canthorum]. The Iris was hypopigmented and bluish in colour in the right eye, whilst the left Iris was brown and darkly pigmented. Discussion: The diagnosis of WS is considered if there are 2 major or 1 major and 2 minor criteria Case Report according to Waardenburg consortium. Our patient had 2 major criteria viz disturbances of the iris and dystopia canthorum. Waardenburg syndrome is sub classified into 4 types. The management of Waardenburg's syndrome, comprises early detection and referral to the appropriate unit including audiology, correction for refractive error and use of cosmetic contact lenses. Conclusion: Waardenburg syndrome is a rare disease. In all su impairment, severe musculoskeletal contractures and Hirschsprungs disease should be ruled out","PeriodicalId":9249,"journal":{"name":"British journal of medicine and medical research","volume":"11 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87168532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-10DOI: 10.9734/BJMMR/2017/29417
I. Obahiagbon, E. Ugiagbe
Background: Gestational trophoblastic and the mean age was 31.27 ± 7.36 years. GTD was found to be less common at the extremes of reproductive age, with the peak prevalence being in the third and fourth decades. Partial mole was commonest (52.4%), followed by complete mole (25.0%) and choriocarcinoma (19.0%). The ratio of the benign to malignant lesions was 4:1. The uterus was the commonest site of GTD accounting for 83.3% of cases, while 16.6% of cases were distributed among ectopic sites. There was failure to clinically or grossly identify molar vesicles in 80.6% of cases of hydatidiform mole; this highlights the relevance of histopathological examination of products of conception of both intrauterine and ectopic gestation. Conclusion: The prevalence of GTD appears to have been rising in this environment in the recent years.
{"title":"Morphological Pattern of Gestational Trophoblastic Disease in the University of Benin Teaching Hospital, Benin City: A Twenty Year Review (1993 – 2012)","authors":"I. Obahiagbon, E. Ugiagbe","doi":"10.9734/BJMMR/2017/29417","DOIUrl":"https://doi.org/10.9734/BJMMR/2017/29417","url":null,"abstract":"Background: Gestational trophoblastic and the mean age was 31.27 ± 7.36 years. GTD was found to be less common at the extremes of reproductive age, with the peak prevalence being in the third and fourth decades. Partial mole was commonest (52.4%), followed by complete mole (25.0%) and choriocarcinoma (19.0%). The ratio of the benign to malignant lesions was 4:1. The uterus was the commonest site of GTD accounting for 83.3% of cases, while 16.6% of cases were distributed among ectopic sites. There was failure to clinically or grossly identify molar vesicles in 80.6% of cases of hydatidiform mole; this highlights the relevance of histopathological examination of products of conception of both intrauterine and ectopic gestation. Conclusion: The prevalence of GTD appears to have been rising in this environment in the recent years.","PeriodicalId":9249,"journal":{"name":"British journal of medicine and medical research","volume":"9 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87233494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-10DOI: 10.9734/BJMMR/2017/32429
M. Tanveer, Ghulam Mohyud Din Chaudhary, Prof. Dr. Asher. Fawwad, Nida Mustafa, M. Khalid, A. Shafi
Objective: To determine the frequency and associated factors of dyslipidemia among obese type 2 diabetes mellitus subjects. Materials and Methods: A total of 377 consecutive subjects diagnosed with Type 2 diabetes mellitus who were falling in the eligibility criteria were included in the study. Complete physical examination was done including weight, height and BMI. All subjects with diabetes were investigated for the presence of dyslipidemia by obtaining a fasting lipid profile. The results were analyzed using SPSS version 20. Results: Out of 377 study cases, 163 (43.2%) were male and 214 (56.8%) were female. Original Dyslipidemia was found to be present in 297 (78.8%) while it was negative in 80 (21.2%) obese type2 diabetics. Presence of dyslipidemia was significantly associated with age (p-value=0.004) and family history (p-value<0.0001) along with the deranged components of lipid profile. Conclusion: It was observed that dyslipidemia was common among obese subjects with type 2 diabetes mellitus, with age and family history as the strong predictors of dyslipidemia.
目的:了解肥胖2型糖尿病患者血脂异常的发生频率及相关因素。材料与方法:共纳入377例连续诊断为2型糖尿病且符合入选标准的受试者。完成了完整的体格检查，包括体重、身高和身体质量指数。所有糖尿病患者均通过空腹血脂检查是否存在血脂异常。采用SPSS version 20对结果进行分析。结果:377例患者中，男性163例(43.2%)，女性214例(56.8%)。297例(78.8%)肥胖2型糖尿病患者有原发性血脂异常，80例(21.2%)肥胖2型糖尿病患者无原发性血脂异常。血脂异常的存在与年龄(p值=0.004)、家族史(p值<0.0001)以及血脂紊乱成分显著相关。结论:肥胖2型糖尿病患者普遍存在血脂异常，年龄和家族史是血脂异常的重要预测因素。
{"title":"Factors Predicting Dyslipidemia in Obese Type 2 Diabetic Subjects","authors":"M. Tanveer, Ghulam Mohyud Din Chaudhary, Prof. Dr. Asher. Fawwad, Nida Mustafa, M. Khalid, A. Shafi","doi":"10.9734/BJMMR/2017/32429","DOIUrl":"https://doi.org/10.9734/BJMMR/2017/32429","url":null,"abstract":"Objective: To determine the frequency and associated factors of dyslipidemia among obese type 2 diabetes mellitus subjects. Materials and Methods: A total of 377 consecutive subjects diagnosed with Type 2 diabetes mellitus who were falling in the eligibility criteria were included in the study. Complete physical examination was done including weight, height and BMI. All subjects with diabetes were investigated for the presence of dyslipidemia by obtaining a fasting lipid profile. The results were analyzed using SPSS version 20. Results: Out of 377 study cases, 163 (43.2%) were male and 214 (56.8%) were female. Original Dyslipidemia was found to be present in 297 (78.8%) while it was negative in 80 (21.2%) obese type2 diabetics. Presence of dyslipidemia was significantly associated with age (p-value=0.004) and family history (p-value<0.0001) along with the deranged components of lipid profile. Conclusion: It was observed that dyslipidemia was common among obese subjects with type 2 diabetes mellitus, with age and family history as the strong predictors of dyslipidemia.","PeriodicalId":9249,"journal":{"name":"British journal of medicine and medical research","volume":"11 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85552062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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