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Comparison of Acidic versus Alkaline Environment for Furcation Perforation Repair among Calcium Silicate Based Materials: An in vitro Comparative Study 酸性与碱性环境对硅酸钙基材料孔洞修复的比较:体外比较研究
Pub Date : 2017-01-10 DOI: 10.9734/bjmmr/2017/14050
Bernice Thomas, M. Chandak, Bharat Deosarkar
Aim: The aim of this study was to compare the effect of acidic and alkaline environment on the dislodgement resistance of White Pro Root Mineral Trioxide Aggregate and Biodentine when used as furcation perforation repair materials. Methodology: Eighty, human, mandibular molars were used. Perforations were made in the furcation of each molar and enlarged to #3 Peeso drills. After perforation repair, according to the two materials respectively, specimens of each material were randomly divided into 4 groups (n = 10) according to storage media and time: group A: phosphate-buffered saline (PBS) (pH = 7.4) for 4 days, group B: acetic acid (pH =5.4) for 4 days, group C: PBS for 34 days, and group D: acetic acid (pH = 5.4) for 4 days followed by exposure to PBS for 30 days. Dislodgment resistance was then measured using a universal testing machine. Results: Biodentine resisted dislodgement more efficiently than Pro Root MTA in PBS (p<0.05). The dislodgement resistance of Biodentine and Pro Root MTA was reduced after exposure to acidic pH, but there was significant reduction of Pro Root MTA in comparison with Biodentine. Conclusion: An acidic environment affects the bond strength of calcium silicate based materials. Biodentine has better dislodgement resistance than White Pro Root Mineral Trioxide Aggregate (MTA).
目的:比较酸性和碱性环境对白亲根矿物三氧化物骨料和生物牙石作为牙槽孔修复材料抗移位能力的影响。方法:使用人类下颌磨牙80颗。在每个磨牙的分叉处穿孔,并扩大到3号Peeso钻。穿孔修复后,分别根据两种材料的保存介质和时间,将每种材料的标本随机分为4组(n = 10): A组:磷酸盐缓冲盐水(PBS) (pH = 7.4)保存4天,B组:乙酸(pH =5.4)保存4天,C组:PBS保存34天,D组:乙酸(pH =5.4)保存4天,再暴露于PBS中30天。然后用万能试验机测量位移阻力。结果:Biodentine比Pro Root MTA在PBS中更有效地抵抗移位(p<0.05)。暴露于酸性pH后,Biodentine和Pro Root MTA的抗移位性降低,但与Biodentine相比,Pro Root MTA明显降低。结论:酸性环境影响硅酸钙基材料的粘结强度。生物牙石碱具有较好的抗移位性。
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引用次数: 2
Family Risk of Metabolic Disorder; A Parameter for Timely Screening of Vascular Endothelial Health 代谢性疾病的家族风险;及时筛选血管内皮健康的一个参数
Pub Date : 2017-01-10 DOI: 10.9734/bjmmr/2017/31004
Preeti Kanawjia, S. Tiwari, M. Bajpai
Aim: To study the correlation of vascular endothelial health with family risk of metabolic disorders, in healthy overweight, obese and non obese subjects. Study Design: A case-control (pilot) study. Place and Duration of Study: The study was conducted in Cardiovascular Physiology lab, Department of Physiology, K.G.M.U Methods: Cases and controls comprised from January 2009 to February 2010. of 30 overweight / obese healthy subjects (BMI >= 25 kg/m2 and/or WHR (female>0.85; male>1) and 30 non-obese healthy subjects respectively (BMI< 25 kg/m2 and/or WHR (female<0.85; male<1) excluding subjects with secondary cause of abnormal blood flow. Vascular endothelial health was assessed via reactive hyperemic response measured via impedance plethysmography in the subject’s forearm. Fasting plasma glucose and serum lipid profile was also done. Results: On comparison of biochemical variables, lipid derangement was recorded in both the groups. Significant difference in VLDL (control 21.84±9.68, case 29.01±16.83) (p=0.048) and TG (control 101.22±-43.33; case145.21±84.02) (p=0.013), could be seen. VLDL & TG was deranged in 15 (6 cases + 9 controls) (P=0.371) and 14 (5 cases + 9 controls) (P=0.222) subjects respectively with no inter-group significant statistical difference. Inter-group reactive hyperemia at 1, 2, 3, 5, 7, 9 min post occlusion time showed no significant difference. Peak hyperemic response was seen at 2 minutes in both the groups. Though independent family history in first degree relatives of diabetes, coronary artery disease and/or hypertension showed a significant association with % RH at 2 min. (P =0.049), yet in group wise exploration, no significant association was seen. Conclusion: Adverse anthropometry is universally not associated with deranged lipid profile and vice versa. Raised RH response associated with positive family risk could be either due to hyperinsulinemia and/or some yet undeciphered cause but not solely as add-on sequelae of deranged anthropometry (BMI & WHR). In the light of our findings, we conclude that what seems as a favourable response i.e. a raised hyperemic response in subjects with a positive family history of risk factors, may be last ditch escape response before the vascular system succumbs to the inflammatory insult. Some yet undeciphered causes could thus be suspected of an adverse outcome and thus accordingly timely modified by lifestyle modifications or pharmacological interventions.
目的:探讨健康超重、肥胖和非肥胖人群血管内皮健康与代谢紊乱家族风险的相关性。研究设计:病例对照(先导)研究。研究地点和时间:研究在K.G.M.U生理学系心血管生理实验室进行。方法:2009年1月至2010年2月为病例和对照组。30名超重/肥胖健康受试者(BMI >= 25 kg/m2和/或WHR(女性>0.85);男性>1)和30名非肥胖健康受试者(BMI< 25 kg/m2和/或WHR(女性<0.85;男性<1),排除继发性血流量异常的受试者。血管内皮健康状况通过反应性充血反应进行评估,该反应性充血反应是通过受试者前臂的阻抗容积描记术测量的。同时测定空腹血糖和血脂。结果:经生化指标比较,两组均有脂质紊乱。VLDL(对照组21.84±9.68,病例29.01±16.83)、TG(对照组101.22±-43.33;Case145.21±84.02)(p=0.013)。VLDL和TG紊乱者15例(6例+ 9例对照)(P=0.371), 14例(5例+ 9例对照)(P=0.222),组间差异无统计学意义。闭塞后1、2、3、5、7、9 min组间反应性充血差异无统计学意义。两组均在2分钟出现充血反应高峰。虽然糖尿病、冠状动脉疾病和/或高血压一级亲属的独立家族史与2 min时的% RH有显著相关性(P =0.049),但在分组探索中,未见显著相关性。结论:人体测量不良与血脂异常无明显相关性,反之亦然。RH反应升高与阳性家族风险相关,可能是由于高胰岛素血症和/或一些尚未解释的原因,但不仅仅是紊乱的人体测量(BMI和WHR)的附加后遗症。根据我们的研究结果,我们得出结论,在具有阳性危险因素家族史的受试者中,似乎是有利的反应,即充血反应升高,可能是血管系统屈服于炎症侮辱之前的最后一根逃生反应。因此,一些尚未解释的原因可能被怀疑是不良结果,因此可以通过改变生活方式或药物干预及时加以纠正。
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引用次数: 0
Relationship between the Inclination of Adjacent Teeth Caused by Vertical Malposition of the Second Primary Molar – in Relation to Development Stage of First Molar 第二乳牙垂直错位引起的邻牙倾斜与第一乳牙发育阶段的关系
Pub Date : 2017-01-10 DOI: 10.9734/bjmmr/2017/29480
Shoji Takahashi, Shigeru Watanabe, Koji Watanabe, Akihiro Nakamura, Reina Odai, T. Sasabe
Aims: Mesial inclination of first molar caused by vertical malposition of the second primary molar is often untreated but this may create severe problems. To obtain an objective guideline for treatment of such cases, the relationship between degree of mesial inclination and developmental phase of first molar was analyzed. Study Design: Ten boys and six girls who exhibited vertical malposition of the second primary molar were analyzed. At their first visit oral checklists and panoramic radiographs were obtained. Methodology: Oral checklists were used at their first visit and panoramic radiographs were taken by Veraview Epocs X-550 (Morita/Kyoto). The radiographs were output as films by DRY PIX7000 (Fujifilm Medical/Tokyo). Examinations were conducted on the degree of development of the second bicuspid germ affected by a submerged second deciduous tooth, the presence of malposition, the degree of development of first molar and presence of tooth root resorption in the second primary molar, based on the panoramic radiographs. Results: A significant positive correlation occurred between (i) second primary molar space and degree of formation of the first molar (p<0.01); (ii) the angle between tooth axes of the first primary molar and first molar and amount of formation of the first molar (p<0.05); The vertical positional relationship between the second primary molar and the second bicuspid germ Proximity values showed larger values on the affected side; Retarded formation by 54% was recognized in the formation of the second bicuspid. Conclusion: The prognosis for treatment success may depend on the degree of first molar formation.
目的:由于第二磨牙垂直错位引起的第一磨牙近中倾斜经常得不到治疗,但这可能会造成严重的问题。本文分析了第一磨牙近中倾斜度与发育阶段的关系,以期获得客观的治疗指导。研究设计:分析了10名男孩和6名女孩表现出第二初级磨牙垂直错位。在第一次就诊时,获得了口腔检查表和全景x光片。方法:首次就诊时使用口腔检查表,并使用Veraview eppocs X-550 (Morita/Kyoto)拍摄全景x线片。通过DRY PIX7000 (Fujifilm Medical/Tokyo)将x光片输出为胶片。根据全景x线片检查浸没的第二乳牙对第二双尖胚芽的影响程度,是否存在移位,第一磨牙的发育程度以及第二第一磨牙的牙根吸收是否存在。结果:(1)第二乳牙间隙与第一磨牙形成度呈显著正相关(p<0.01);(ii)第一初级磨牙与第一磨牙牙轴夹角及第一磨牙的形成量(p<0.05);第二初磨牙与第二双尖胚芽垂直位置关系接近值在患侧较大;在第二双尖牙的形成过程中,有54%的发育迟缓。结论:第一磨牙的形成程度与治疗成功与否有关。
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引用次数: 0
Practice of Effective Hand Washing and Associated Factors among Caregivers of Infants Attending Infant Welfare Clinics in Ado-Ekiti, Ekiti State, Nigeria 尼日利亚埃基蒂州阿多-埃基蒂婴儿福利诊所婴儿护理人员有效洗手的实践及相关因素
Pub Date : 2017-01-10 DOI: 10.9734/BJMMR/2017/31836
O. Odu, E. Emmanuel, E. Amu, S. Deji, S. Dada, O. Marcus
Introduction: Effective hand washing has been shown to reduce the incidence of some infectious diseases especially diarrhea participants. SPSS version 20 was used for data analysis. The level of significance was set at P< 0.05. Results: A total of 387 caregivers participated in the study. About 89.9% of the respondents had good knowledge of hand washing, while 7.5% and 2.6% of the respondents had fair and poor knowledge respectively. Similarly, about 77.3% of the respondents had positive attitude towards the practice of effective hand washing. However, less than one third (31.5%) of the respondents were observed to be practicing effective hand washing. The study also revealed that knowledge and attitude of respondents towards hand washing were significantly associated with the practice of effective hand washing among the caregivers. Conclusion: The study revealed that the knowledge of hand washing was generally high among the caregiver while the observed practice of effective hand washing was generally low. It also revealed a gap between self-reported practice and observed practice of hand washing. Knowledge and attitude of caregivers towards hand washing were identified as significant factors associated with the practice of effective hand washing while behavioural change communication was recommended for caregivers.
有效的洗手已被证明可以减少一些传染病的发病率,特别是腹泻参与者。使用SPSS version 20进行数据分析。P< 0.05为显著性水平。结果:共有387名护理人员参与了本研究。89.9%的受访者对洗手有良好的认识,7.5%的受访者对一般的认识,2.6%的受访者对较差的认识。同样,约77.3%的受访者对有效洗手持积极态度。然而,不到三分之一(31.5%)的答复者被观察到进行有效的洗手。研究还发现,受访者对洗手的知识和态度与照顾者有效洗手的实践显著相关。结论:本研究发现护理人员洗手知识普遍较高,而观察到的有效洗手行为普遍较低。它还揭示了自我报告的洗手行为和观察到的洗手行为之间的差距。研究发现,护理人员对洗手的知识和态度是影响有效洗手行为的重要因素,并建议对护理人员进行行为改变沟通。
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引用次数: 8
Assessment of Skills and Knowledge in Clinical Ophthalmology: A Survey among Undergraduate Medical Students in Malaysia 临床眼科学技能和知识的评估:马来西亚医科本科生的调查
Pub Date : 2017-01-10 DOI: 10.9734/BJMMR/2017/30941
S. C. Reddy, S. Moe
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引用次数: 0
Evaluation of Ricketts Frontal Analysis Reference Points on Cone-beam Computed Tomography Images 锥束计算机断层成像中Ricketts正面分析参考点的评价
Pub Date : 2017-01-10 DOI: 10.9734/bjmmr/2017/32451
A. Rosa, Lívia Silva, L. Chinem, B. Vilella, A. Motta, O. V. Vilella
Aims: The aim of this study was to evaluate the reliability of Ricketts frontal analysis reference points when viewed by three-dimensional images. Methodology: The points related to the Ricketts frontal analysis were identified at multiplanar reconstructions (MPR) and three-dimensional reconstructions (Rec 3D) obtained from cone-beam computed tomography. The cephalometric landmarks, following the author’s definition, were located by three operators: an orthodontist, a radiologist, and a student coursing the eighth period of the graduation course in dentistry. After two weeks, the landmarks were repeated. The values of X, Y, and Z were obtained for each point, and the intraclass correlation coefficient was calculated. Results: The intraclass correlation coefficient values were less than 0.45 (poor reliability) at 15 points viewed from the three-dimensional reconstructions and 8 points for the multiplanar reconstructions, including the intra and interobserver assessments. It was not possible to identify the J point on the CBCT images. Conclusion: The multiplanar reconstructions allow greater reliability in the identification of the anatomical landmarks for both intra and interobserver assessments. To improve its reliability, Ricketts frontal analysis reference points must be defined in the three planes of space before transfer to three-dimensional images, or new anatomical references can be adopted.
目的:本研究的目的是评估Ricketts正面分析参考点在三维图像上的可靠性。方法:在锥形束计算机断层扫描获得的多平面重建(MPR)和三维重建(Rec 3D)中识别与Ricketts正面分析相关的点。根据作者的定义,由三名操作人员定位了头测地标:一名正畸医生、一名放射科医生和一名参加牙科毕业课程第八期课程的学生。两周后,重复地标。得到每个点的X、Y、Z值,并计算类内相关系数。结果:三维重建的15个点和多平面重建的8个点(包括观察者内部和观察者之间的评估)的类内相关系数值小于0.45(信度较差)。在CBCT图像上无法识别出J点。结论:多平面重建可以更可靠地识别观察者内部和观察者之间的解剖标志。为了提高Ricketts正面分析的可靠性,必须在空间的三个平面上定义Ricketts正面分析参考点,然后再转换为三维图像,或者采用新的解剖参考点。
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引用次数: 0
Comparative Safety Profiles of Pure and Alcohol Beverages in Wistar Rats 纯饮料和酒精饮料对Wistar大鼠的安全性比较
Pub Date : 2017-01-10 DOI: 10.9734/bjmmr/2017/25624
O. Dawodu, O. Ebuehi, O. Odesanmi
Objective: Alcohol consumption is readily acceptable worldwide, and despite warnings and billions of dollars spent yearly on its the present copious of The study investigated the comparative effects of pure and alcoholic on Wistar rats to in treatment compared GGT and activities of the treatment rat organ photomicrographs showed followed by the liver, kidney and brain. The GC-MS chromatograms of the respective beverages contained the following: beer 19, red wine 10 and spirit 16 constituents. Conclusion: The plasma ALT, AST, GGT activities however, did not indicate excess alcohol consumption in the animals although unusual values were observed. The histological profile on the rat organs showed that there was some form of organ damage implying that these beverages may be injurious to health. In addition, the GC-MS spectroscopy revealed that these alcoholic beverages had different proportions of the chemical constituents which may portend some futuristic threat to health.
目的:酒精消费在世界范围内是可以接受的,尽管有警告和每年数十亿美元的花费,但目前大量的研究调查了纯酒精和酒精对Wistar大鼠的比较作用,在治疗中比较了GGT和治疗大鼠器官的活动,显微照片显示,其次是肝脏,肾脏和大脑。各饮料的GC-MS色谱包含以下成分:啤酒19,红酒10和烈酒16。结论:血浆ALT、AST、GGT活性虽有异常值,但未提示动物饮酒过量。对大鼠器官的组织学分析显示存在某种形式的器官损伤,这意味着这些饮料可能对健康有害。此外,气相色谱-质谱分析显示,这些酒精饮料的化学成分比例不同,这可能预示着未来对健康的威胁。
{"title":"Comparative Safety Profiles of Pure and Alcohol Beverages in Wistar Rats","authors":"O. Dawodu, O. Ebuehi, O. Odesanmi","doi":"10.9734/bjmmr/2017/25624","DOIUrl":"https://doi.org/10.9734/bjmmr/2017/25624","url":null,"abstract":"Objective: Alcohol consumption is readily acceptable worldwide, and despite warnings and billions of dollars spent yearly on its the present copious of The study investigated the comparative effects of pure and alcoholic on Wistar rats to in treatment compared GGT and activities of the treatment rat organ photomicrographs showed followed by the liver, kidney and brain. The GC-MS chromatograms of the respective beverages contained the following: beer 19, red wine 10 and spirit 16 constituents. Conclusion: The plasma ALT, AST, GGT activities however, did not indicate excess alcohol consumption in the animals although unusual values were observed. The histological profile on the rat organs showed that there was some form of organ damage implying that these beverages may be injurious to health. In addition, the GC-MS spectroscopy revealed that these alcoholic beverages had different proportions of the chemical constituents which may portend some futuristic threat to health.","PeriodicalId":9249,"journal":{"name":"British journal of medicine and medical research","volume":"28 1","pages":"1-11"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73355546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Delirious Mania: Recognition and Successful Treatment with Donepezil 谵妄性躁狂:多奈哌齐的识别和成功治疗
Pub Date : 2017-01-10 DOI: 10.9734/BJMMR/2017/33433
L. Moore, M. Goldner-Vukov, R. Huso
Aims: Presentation of a case of severe delirious mania with resolution of delirium after treatment with donepezil. Presentation of Case: KA was a 44 y/o Australian female with a history of bipolar affective disorder with psychotic manic episodes. Two weeks prior to her psychiatric admission she was admitted to a medical ward after an overdose (OD) of acetaminophen. On review, it appeared that pathological processes involved in delirium may require unique and individual recognition and management. Conclusion: This case suggests that the use of donepezil is strongly recommended in the treatment of delirious mania. Further study is required to clarify in this challenging disorder.
目的:报告1例重度谵妄性躁狂症经多奈哌齐治疗后谵妄消退的病例。病例介绍:KA是一名44岁的澳大利亚女性,有双相情感障碍和精神病性躁狂发作的病史。在精神科住院前两周,她因服用过量对乙酰氨基酚而被送进病房。回顾,它似乎病理过程涉及谵妄可能需要独特的和个人的认识和管理。结论:本病例提示强烈推荐使用多奈哌齐治疗谵妄性躁狂症。需要进一步的研究来阐明这种具有挑战性的疾病。
{"title":"Delirious Mania: Recognition and Successful Treatment with Donepezil","authors":"L. Moore, M. Goldner-Vukov, R. Huso","doi":"10.9734/BJMMR/2017/33433","DOIUrl":"https://doi.org/10.9734/BJMMR/2017/33433","url":null,"abstract":"Aims: Presentation of a case of severe delirious mania with resolution of delirium after treatment with donepezil. Presentation of Case: KA was a 44 y/o Australian female with a history of bipolar affective disorder with psychotic manic episodes. Two weeks prior to her psychiatric admission she was admitted to a medical ward after an overdose (OD) of acetaminophen. On review, it appeared that pathological processes involved in delirium may require unique and individual recognition and management. Conclusion: This case suggests that the use of donepezil is strongly recommended in the treatment of delirious mania. Further study is required to clarify in this challenging disorder.","PeriodicalId":9249,"journal":{"name":"British journal of medicine and medical research","volume":"33 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74530263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Evaluation of Fracture Resistance and Microleakage of Reattached Anterior Tooth Fragment Using Two Different Flowable Composites- An in vitro Study 两种不同的可流动复合材料对前牙碎片再附着的抗折性和微渗漏的比较研究
Pub Date : 2017-01-10 DOI: 10.9734/bjmmr/2017/32526
Saumya, R. Dhingra, Ashish Gupta, B. Karunanand
Aim: To evaluate and compare the fracture resistance and microleakage of reattached anterior tooth fragment using two different flowable composites. Study Design: In-vitro study. Place and of Study: The present in vitro study was carried out in the Department between June and July 2016. Methodology: The subjects were selected from various sources. A total of 160 extracted permanent anteriors were selected for the study. Teeth were divided into 2 groups, 80 teeth in each group reattached with G-aenial Universal Flo and Esthet X-Flow, evaluated for fracture resistance testing using Universal testing machine. Half number of teeth tested for microleakage using Dye-penetration method. The results obtained from the study were then tabulated and statistically analyzed. Results: Mean value for fracture resistance in Group I were observed (89.07 ± 32.46) whereas in Group II were observed (64.63 ± 40.33). On statistical analysis result found to be highly significant (p = 0.001). Out of 40 teeth, in Group I -16 observed no penetration whereas in Group II -10 teeth were observed no penetration. On Enamel-Dentin microleakage in Group I found to be in 6 teeth, whereas 14 teeth showed the same Enamel-Dentin penetration in Group II. But on statistical analysis, overall result found to be non-significant (p = 0.19). Conclusion: Among the tested flowable composites, G-aenial Universal Flo showed highly significant fracture resistance than Esthet X-flow. Microleakage shows no significant differences between nanohybrid and microhybrid flowable composites.
目的:评价和比较两种不同的可流动复合材料对前牙碎片再植的抗骨折性和微渗漏的影响。研究设计:体外研究。研究地点:本体外研究于2016年6月至7月在该系进行。方法:研究对象从不同的来源中选择。本研究共选取160例拔除的恒牙前牙进行研究。将牙分为2组,每组80颗牙分别用g - enial Universal Flo和Esthet X-Flow重新附着,在万能试验机上进行抗断性测试。用染料渗透法检测一半牙齿的微泄漏。从研究中得到的结果被制成表格并进行统计分析。结果:ⅰ组骨折阻力平均值为89.07±32.46,ⅱ组骨折阻力平均值为64.63±40.33。经统计分析发现结果极显著(p = 0.001)。在40颗牙中,I组-16颗牙未观察到渗透,II组-10颗牙未观察到渗透。第一组有6颗牙釉质-牙本质微渗漏,第二组有14颗牙釉质-牙本质微渗漏。但在统计分析上,发现总体结果不显著(p = 0.19)。结论:在所测试的可流动复合材料中,g - enial Universal Flo比Esthet X-flow具有显著的抗断裂性能。微泄漏在纳米复合材料和微混合流动复合材料之间没有显著差异。
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引用次数: 2
Transcutaneous Electrical Nerve Stimulation (TENS) in the Immediate Postoperative Period Following Proximal Femoral Fractures Reduces Drug Costs 经皮神经电刺激(TENS)在股骨近端骨折术后立即减少药物费用
Pub Date : 2017-01-10 DOI: 10.9734/BJMMR/2017/31860
F. Silva, E. Bobsin, J. Grings, M. Silveira, A. Rosa, M. B. Dohnert
Aim: The aim of this study was to evaluate the effect of TENS on the costs generated with the intake of analgesic drugs in patients with proximal femoral fractures. Study Design: Randomized, double-blind, placebo-controlled clinical trial. Methodology: Forty-two patients, homogeneous for age, color and sex, were allocated into three groups. These were divided into TENS treatment (n=14), Placebo TENS (n=14) and Control (n=14), with application for a period of seventy-two hours postoperatively, assessing pain, by visual analogue scale, and drug intake (tenoxicam, dipyrone, tramadol, morphine and diazepam). Results: Long-term TENS reduced pain and drug intake by 62.96% (tramadol), 45.61% (tenoxicam), 24% (dipyrone) and 87.5% (morphine) in patients in the postoperative period following femoral fracture. This reduction represented a decrease of US$ 3,975.34 for every 1,000 patients with proximal femoral fractures treated with TENS on the three days after surgery. Conclusion: TENS, when used ininterrupedly, was shown to be effective for pain reduction and generated a significant reduction in drug-related costs in the immediate postoperative period of patients with proximal femoral fractures.
目的:本研究的目的是评估TENS对股骨近端骨折患者服用镇痛药物成本的影响。研究设计:随机、双盲、安慰剂对照临床试验。方法:42例年龄、肤色、性别均相同的患者分为三组。将这些患者分为TENS治疗组(n=14)、安慰剂组(n=14)和对照组(n=14),术后72小时应用TENS,通过视觉模拟量表评估疼痛,以及药物摄入(替诺西康、地吡酮、曲马多、吗啡和地西泮)。结果:长期TENS可使股骨骨折术后患者的疼痛和药物摄入分别减少62.96%(曲马多)、45.61%(替诺昔康)、24%(地吡酮)和87.5%(吗啡)。这一减少意味着在术后三天内,每1000名接受TENS治疗的股骨近端骨折患者减少3,975.34美元。结论:间断使用TENS可有效减轻股骨近端骨折患者术后即刻疼痛,并显著降低药物相关费用。
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引用次数: 2
期刊
British journal of medicine and medical research
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