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Hyponatremia in Acute Decompensated Heart Failure as a Predictor of Acute Cardiorenal Syndrome Type-1 急性失代偿性心衰患者低钠血症作为急性心肾综合征1型的预测因子
Pub Date : 2023-04-11 DOI: 10.25259/ijcdw_27_2022
Acute cardiorenal syndrome (CRS type-1) refers to an acute worsening of heart function, leading to acute kidney injury (AKI), frequently complicating acute decompensated heart failure (ADHF). This study aims to investigate whether hyponatremia, is a surrogate marker for the development of AKI in patients admitted with ADHF.Sample size – 100 patients with ADHF. Age – More than 18 years. Investigations – 2D-ECHO, N-terminal pro-brain natriuretic peptide, kidney function test, estimated glomerular filtration rate, USG abdomen, complete blood picture, chest X-ray, and complete urine examination.On analysis of data, 63.5% (n=33) of patients who had hyponatremia (n=45) eventually developed AKI during hospital stay, whereas 36.5% (n=19) of patients who did not have hyponatremia (n=36) developed AKI. Hyponatremia was found to be a statistically significant (P = 0.001) predictor of increased incidence of AKI in a predetermined group of patients with HF in our study, and ADHF patients with hyponatremia have a 5.21-fold higher risk of developing AKI (95% CI, 2.20–12.36) than ADHF patients without hyponatremia.Hyponatremia predicts complications while admission in heart failure patients like type-I CRS and it has also been shown that comorbidities could play an important role in the presence or absence of hyponatremia and could even influence the length of hospital stay attributed to lower serum sodium levels which need further clinical trials.
急性心肾综合征(CRS -1型)是指心功能急性恶化,导致急性肾损伤(AKI),常并发急性失代偿性心力衰竭(ADHF)。本研究旨在探讨低钠血症是否是ADHF患者AKI发展的替代标志物。样本量:100例ADHF患者。年龄- 18岁以上。检查- 2D-ECHO, n端脑利钠肽前体,肾功能检查,估计肾小球滤过率,腹部USG,全血图,胸部x线,全尿检查。在数据分析中,63.5% (n=33)的低钠血症患者(n=45)最终在住院期间发生AKI,而36.5% (n=19)的非低钠血症患者(n=36)发生AKI。在我们的研究中,低钠血症被发现是一组预先确定的HF患者AKI发生率增加的具有统计学意义(P = 0.001)的预测因子,并且伴有低钠血症的ADHF患者发生AKI的风险比无低钠血症的ADHF患者高5.21倍(95% CI, 2.20-12.36)。低钠血症预示着i型CRS等心力衰竭患者入院时的并发症,同时也有研究表明,合并症可能在低钠血症存在与否中发挥重要作用,甚至可能影响由于血清钠水平较低而住院的时间,这需要进一步的临床试验。
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引用次数: 1
Female Gender and COVID-19 Aftermath: Audacious Times Ahead? 女性性别与COVID-19后果:大胆的未来时代?
Pub Date : 2023-04-11 DOI: 10.25259/ijcdw_31_2023
P. Kapoor
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引用次数: 0
Bending Saturation Index – A Novel Index of Old Symptom a Marker of Elevated Filling Pressure in Heart Failure 弯曲饱和指数——一种新的老症状指标——心衰充血压力升高的标志
Pub Date : 2023-04-11 DOI: 10.25259/ijcdw_5_2023
Purushotham Reddy
Bendopnea is a symptom in patients with heart failure (HF) defined as shortness of breath when bending forward. It is mediated by increased ventricular filling pressure during bending forward. Qualification of bendopnea and its correltion with other symptoms and parameters of HF is not a much explored area. In this study, we studied the frequency of bendopnea in patients admitted with HF and a index of difference between sitting and bending saturations and its correlation with clinical, laboratory, and echocardiographic and short-term mortality.We conducted a study of 150 patients admitted with DHF in the span of 5 month and followed for 1 month. Bendopnea is defined as subjective sensation of worsening shortness of breath after bending for 1 min or more. Saturations after bending for 1 min are also recorded for each patient. Bendopnea saturation index (BOSI) is calculated as difference between saturations at baseline and after bending over, its percentage over baseline saturation (SaO2 sitting - SaO2 bending/SaO2 sitting*100).It was present in 61 patients (40.7%). Among 150 patients, 11 patientns (7.3%) expired. Orthopnea was more frequent in patients with bendopnea compared to patients without (59% of patients with bendopnea also had orthopnea and 34.8% of patients without bendopnea had orthopnea, and the difference was statistically significant (P = 0.03). Paroxysmal nocturnal dyspnea (PND) was present in 29.5% of patients with bendopnea and 11% of patients without bendopnea (P = 0.05). The patients with bendopnea had higher right ventricular systolic pressure (RVSP) (49.9 ± 1.6) compared to patients without bendopnea (33.5 ± 0.9). Average NT pro BNP values were 8717 ± 950 pg/mL in patients with bendopnea and 1110 ± 99 pg/mL in patients without bendopnea (P < 0.005). Mean BOSI was 4.4 (±2.9) in patients with bendopnea and 0.4 (±0.09) in patients without bendopnea. There was a negative correlation between BOSI and left ventricular ejection fraction (LVEF), and positive correlation between BOSI and RVSP. Among patients with bendopnea, six patients expired, when compared with patients who were alive after 1 month using t-test, patients who expired have higher average BOSI (P < 0.005).Bendopnea and falling of desaturation on bending is a sign of significance in HF patients. The presence of bendopnea correlated with increased pulmonary arterial pressure and with other symptoms of respiratory variation, namely – orthopnea and PND, and higher values of biomarker (NTproBNP). BOSI, but not bendopnea had significant positive correlation with RVSP, and negative correlation with LVEF. BOSI also correlated with short-term mortality.
腹屈通气是心力衰竭(HF)患者的一种症状,定义为向前弯腰时呼吸急促。它是由前屈时心室充盈压力增加介导的。弯曲通气的鉴定及其与心衰其他症状和参数的相关性还不是一个深入研究的领域。在这项研究中,我们研究了心力衰竭住院患者的弯曲通气频率、坐姿和弯曲饱和度的差异指数及其与临床、实验室、超声心动图和短期死亡率的相关性。我们对150例DHF患者进行了为期5个月的研究,随访1个月。弯曲呼吸暂停被定义为弯曲1分钟或更长时间后呼吸急促加重的主观感觉。同时记录每位患者弯曲1分钟后的饱和度。弯曲饱和度指数(BOSI)计算为基线和弯曲后饱和度之差,其超过基线饱和度的百分比(SaO2坐姿- SaO2弯曲/SaO2坐姿*100)。61例(40.7%)患者出现此病。150例患者中有11例(7.3%)死亡。有弯管通气的患者出现矫直的频率高于无弯管通气的患者(有弯管通气的患者中有59%同时发生矫直,无弯管通气的患者中有34.8%同时发生矫直,差异有统计学意义(P = 0.03)。发作性夜间呼吸困难(PND)出现在29.5%的腰鼓通气患者和11%的非腰鼓通气患者中(P = 0.05)。右心室收缩压(RVSP)(49.9±1.6)高于非右心室收缩压(33.5±0.9)。有弯腔通气患者NT pro BNP平均值为8717±950 pg/mL,无弯腔通气患者NT pro BNP平均值为1110±99 pg/mL (P < 0.005)。有弯曲通气患者平均BOSI为4.4(±2.9),无弯曲通气患者平均BOSI为0.4(±0.09)。BOSI与左室射血分数(LVEF)呈负相关,与RVSP呈正相关。在benendopnea患者中,有6例患者死亡,经t检验,与存活1个月的患者相比,死亡患者的平均BOSI更高(P < 0.005)。弯曲通气和弯曲时的去饱和度下降是心衰患者的重要标志。弯曲通气的存在与肺动脉压升高、其他呼吸变异症状(即- orthopnea和PND)以及较高的生物标志物(NTproBNP)值相关。BOSI与RVSP呈显著正相关,与LVEF呈显著负相关,但与bendopnea无显著正相关。BOSI还与短期死亡率相关。
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引用次数: 0
Post Myocardial Infarction – Heart Failure Recurrence and Outcomes, Does Gender Play an Important Role? 心肌梗死后心衰复发及预后,性别是否起重要作用?
Pub Date : 2023-04-11 DOI: 10.25259/ijcdw_23_2023
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引用次数: 1
Advances in Intravascular Ultrasound 血管内超声研究进展
Pub Date : 2023-03-27 DOI: 10.25259/ijcdw_2_2023
Archana Remala, Kapil Karthikeya Reddy, P. Velagapudi
Since its inception, intravascular ultrasound (IVUS) and optical coherence tomography (OCT) have played a significant role in evaluating the pathophysiology of coronary artery disease (CAD) guiding the interventional and medical management of CAD improving outcomes in patients. Although the benefits of each of these modalities have been proven, due to some limitations, no single intravascular imaging technique has been proven to provide a detailed and complete evaluation of all CAD lesions. The use of different intravascular imaging modalities sequentially may lead to complications, which are cumbersome, consume time, and add financial burden to the patient. Recently, hybrid imaging catheters that combine OCT and IVUS benefits have been developed to limit these problems. Intravascular imaging techniques we are using currently have some drawbacks that hinder accurate assessment of plaque morphology and pathobiology as demonstrated in many histological studies, causing difficulty in identifying high-risk plaques. To overcome these limitations, great efforts have been put into developing hybrid, dual-probe catheters by combining imaging modalities to get an accurate analysis of plaque characteristics, and high-risk lesions. At present, many dual-probe catheters are available including combined IVUS-OCT, near-infrared spectroscopy-IVUS that is available commercially, the OCT-near infrared fluorescence (NIRF) molecular imaging, IVUS-NIRF, and combined fluorescence lifetime-IVUS imaging. Application of this combined multimodal imaging in clinical practice overcomes the limitations of standalone imaging and helps in providing a comprehensive and accurate visualization of plaque characteristics, composition, and plaque biology. The present article summarizes the advances in hybrid intravascular imaging, analyses the technical hindrances that should be known to have a use in the different clinical circumstances, and the till date shreds of evidence available from their first clinical application aiming to bring these modalities into the limelight and their potential role in the study of CAD.
自成立以来,血管内超声(IVUS)和光学相干断层扫描(OCT)在评估冠状动脉疾病(CAD)的病理生理方面发挥了重要作用,指导了CAD的介入和医疗管理,改善了患者的预后。虽然这些方法的优点已被证实,但由于一些局限性,没有一种血管内成像技术被证明可以提供所有CAD病变的详细和完整的评估。依次使用不同的血管内成像方式可能导致并发症,这是麻烦的,消耗时间,并增加了患者的经济负担。最近,结合OCT和IVUS优点的混合成像导管已经开发出来,以限制这些问题。我们目前使用的血管内成像技术存在一些缺陷,许多组织学研究表明,这些缺陷阻碍了对斑块形态和病理生物学的准确评估,导致难以识别高风险斑块。为了克服这些局限性,人们已经投入了巨大的努力,通过结合成像方式开发混合双探针导管,以准确分析斑块特征和高危病变。目前,有多种双探头导管可供选择,包括IVUS-OCT联合、市售的近红外光谱- ivus、oct -近红外荧光(NIRF)分子成像、IVUS-NIRF和荧光终身- ivus联合成像。这种联合多模态成像在临床实践中的应用克服了单独成像的局限性,有助于提供斑块特征、组成和斑块生物学的全面而准确的可视化。本文总结了混合血管内成像的进展,分析了在不同临床情况下应该知道的技术障碍,以及从首次临床应用中获得的证据,旨在使这些模式成为人们关注的焦点,以及它们在CAD研究中的潜在作用。
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引用次数: 0
Epicardial Fat Tissue Thickness as a Cardiovascular Risk Marker and its Association with Microalbuminuria in Patients with Essential Hypertension 原发性高血压患者心外膜脂肪组织厚度作为心血管危险标志物及其与微量白蛋白尿的关系
Pub Date : 2023-03-24 DOI: 10.25259/ijcdw_24_2022
C. Kashyap, Hemanth Harish
Hypertension is one of the essential modifiable risk factors in causing stroke, renal disease, cardiovascular diseases, and peripheral artery disease. Epicardial fat tissue is regarded as endocrine organ and is metabolically active as it produces angiotensinogen and free fatty acids which are proinflammatory cytokines and are atherogenic. The presence of microalbuminuria has been associated with endothelial dysfunction that predisposes to cardiovascular events. The aim of this study is to determine the association of epicardial fat tissue with age, sex, serum creatinine, left ventricular (LV) mass, serum albumin, low-density lipoprotein (LDL), and triglycerides in patients with essential hypertension.One hundred patients with essential hypertension were divided into two groups each having 50 patients. Group A included urinary albumin creatinine ratio (UACR) <30 mg/g. Group B included UACR >30 mg/g. Age, body mass index, blood pressure, creatinine, urea, albumin, LDL, triglycerides, and epicardial adipose tissue thickness (EAT) were evaluated and compared between two groups. All patients underwent UACR, transthoracic echocardiography to determine EAT, LV mass, and ejection fraction.In our study, EAT ranged from 2 mm to 6.9 mm, with mean value of 3.21 mm and 5.12 mm in Groups A and B, respectively. Mean EAT values were found to be higher in Group B compared to A and was found to be statistically significant. Similarly, LDL, triglycerides, serum albumin levels, and LV mass showed significant difference among two groups. Serum albumin level in Group B was significantly reduced than the patients with normal urine albumin creatinine ratio.EAT serve as an important indicator in patients with essential hypertension to determine target organ damage and to stratify high risk group.
高血压是引起中风、肾脏疾病、心血管疾病和外周动脉疾病的重要可改变危险因素之一。心外膜脂肪组织被认为是内分泌器官,代谢活跃,因为它产生血管紧张素原和游离脂肪酸,这是促炎细胞因子和动脉粥样硬化。微量白蛋白尿的存在与内皮功能障碍有关,内皮功能障碍易导致心血管事件。本研究的目的是确定原发性高血压患者心外膜脂肪组织与年龄、性别、血清肌酐、左心室(LV)质量、血清白蛋白、低密度脂蛋白(LDL)和甘油三酯的关系。100例原发性高血压患者分为两组,每组50例。A组尿白蛋白肌酐比值(UACR) 30 mg/g。评估并比较两组患者的年龄、体重指数、血压、肌酐、尿素、白蛋白、LDL、甘油三酯和心外膜脂肪组织厚度(EAT)。所有患者均行UACR、经胸超声心动图检查EAT、左室肿块和射血分数。在我们的研究中,EAT从2 mm到6.9 mm不等,A组和B组的平均值分别为3.21 mm和5.12 mm。B组平均EAT值高于A组,差异有统计学意义。同样,LDL、甘油三酯、血清白蛋白水平和左室质量在两组之间也有显著差异。B组血清白蛋白水平明显低于尿白蛋白肌酐比正常的患者。EAT是原发性高血压患者判断靶器官损害、划分高危人群的重要指标。
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引用次数: 0
Management of In-stent Restenosis 支架内再狭窄的处理
Pub Date : 2023-03-24 DOI: 10.25259/ijcdw_25_2023
S. Chhabra, J. Majella
Despite recent improvements in percutaneous coronary intervention (PCI), in-stent restenosis (ISR) — which accounts for 5–10% of all PCI procedures in contemporary clinical practice remains a substantial problem and the most frequent reason for stent failure. While the absolute number of ISR-PCI operations performed in contemporary practice has increased as a result of rising procedural volume and complexity, the relative rate of ISR has decreased with newer-generation drug eluting stents (DESs) in comparison to the bare metal stent (BMS) period. While BMS ISR is usually early and characterized by neointimal hyperplasia, DES ISR tends to be late with neoatherosclerosis as a characteristic feature. According to recent research, drug-coated balloons or DESs are the most effective therapy options for the majority of ISR cases. Future ISR interventional paradigms may be influenced by intravascular imaging (IVI) ISR tissue patterns. IVI can provide useful information to guide treatment options in ISR-PCI.
尽管最近经皮冠状动脉介入治疗(PCI)技术有所进步,但支架内再狭窄(ISR)仍然是一个重大问题,也是导致支架失效的最常见原因。在当代临床实践中,支架内再狭窄占所有PCI手术的5-10%。虽然由于手术体积和复杂性的增加,在当代实践中进行的ISR- pci手术的绝对数量有所增加,但与裸金属支架(BMS)时期相比,新一代药物洗脱支架(DESs)的ISR相对率有所下降。BMS ISR通常是早期的,以内膜增生为特征,而DES ISR往往是晚期的,以新动脉粥样硬化为特征。根据最近的研究,药物包被气球或DESs是大多数ISR病例最有效的治疗选择。未来的ISR介入模式可能受到血管内成像(IVI) ISR组织模式的影响。IVI可以提供有用的信息来指导ISR-PCI的治疗选择。
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引用次数: 0
Predictors of Post-catheterization Femoral Artery Pseudoaneurysm 导管置管后股动脉假性动脉瘤的预测因素
Pub Date : 2023-03-23 DOI: 10.25259/ijcdw_24_2023
S. Rajashekhar, Achukatla Kumar
To compare the affected patients with the age- and sex-matched patients in the control group.All patients who had undergone PCI, left heart catheterization, or coronary angiography between July and November 2022 were prospectively recruited. We included 247 patients in our study who underwent cardiac catheterization via femoral access.The incidence of FAP after a diagnostic catheterization was 5.97% and 8.69% after an interventional procedure. The mean age of the patients with FAP was 54.06 ± 15.04 years and 62.5% patients were females in the affected group. In FAP group, 14 patients (87.5%) had hypertension, 8 patients (50%) had diabetes, and 37.5% were had obesity. The systolic blood pressure was 145.38 ± 29.99 mmHg, while the diastolic blood pressure was 86 ± 14.59 mmHg. Data obtained from computed tomography scanning showed that the arterial wall of the CFA was healthy in 11 patients (68.5%), while diffuse atherosclerosis was detected in 5 (31.5%) patients. In 69% of the patients, FAPs were connected to the CFA and in 31% patients to the superficial femoral artery (SFA). In 38% (6) patients partial thrombosis of the pseudoaneurysm sac observed.FAP is a common vascular complication after a diagnostic procedure or percutaneous cardiac catheterization, and its prevalence is likely to rise.
将受影响的患者与年龄和性别匹配的对照组患者进行比较。所有在2022年7月至11月期间接受PCI、左心导管或冠状动脉造影的患者均被前瞻性招募。在我们的研究中,我们纳入了247例通过股骨通道进行心导管置入术的患者。诊断性置管后FAP发生率为5.97%,介入性手术后为8.69%。FAP患者的平均年龄为54.06±15.04岁,其中62.5%为女性。FAP组高血压14例(87.5%),糖尿病8例(50%),肥胖37.5%。收缩压为145.38±29.99 mmHg,舒张压为86±14.59 mmHg。计算机断层扫描数据显示,11例(68.5%)患者CFA动脉壁健康,5例(31.5%)患者弥漫性动脉粥样硬化。69%的患者FAPs连接到CFA, 31%的患者连接到股浅动脉(SFA)。在38%(6)患者中观察到假性动脉瘤囊部分血栓形成。FAP是诊断性手术或经皮心导管插入术后常见的血管并发症,其患病率可能会上升。
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引用次数: 0
Complications of PCI and its Management PCI的并发症及处理
Pub Date : 2023-03-23 DOI: 10.25259/ijcdw_20_2023
A. Mahilmaran
Contemporary percutaneous coronary intervention (PCI) has few complications and enhanced safety on one hand and on the other hand, available modern tools have enabled interventional cardiologists to venture into more complex patient subsets and fresh challenges in tackling the ensuing newer complications. Individual operators may take several years of experience before being exposed to the complications and hence, it is important to learn from the collective experience on the detection and management of these complications and better equipped to handle them when the need arises. The complications of PCI can be access related or coronary intervention related. The common acute coronary complications include abrupt vessel closure, thrombus, slow flow, dissection, perforation, stent dislodgement, and guidewire fracture and embolization. The chronic complications include late stent thrombosis, in-stent restenosis, and aneurysm formation. The use of imaging, physiology, and plaque modification tools are associated with specific complications which need to be kept in mind while using them. The successful management of complications needs prompt recognition, involving help from others and continued team effort and vigilance.
当代经皮冠状动脉介入治疗(PCI)一方面并发症少,安全性高,另一方面,可用的现代工具使介入心脏病专家能够冒险进入更复杂的患者亚群,并在应对随之而来的新并发症方面面临新的挑战。单个操作人员可能需要几年的经验才能接触到这些并发症,因此,从这些并发症的检测和管理方面的集体经验中学习,并在需要时更好地处理它们,是很重要的。PCI的并发症可能与通路相关,也可能与冠状动脉介入相关。常见的急性冠状动脉并发症包括血管突然关闭、血栓、血流缓慢、夹层、穿孔、支架移位、导丝断裂和栓塞。慢性并发症包括支架晚期血栓形成、支架内再狭窄和动脉瘤形成。影像学、生理学和斑块修饰工具的使用与特定并发症相关,在使用它们时需要牢记这些并发症。并发症的成功管理需要及时识别,包括他人的帮助和持续的团队努力和警惕。
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引用次数: 0
Correlation of Aortic Root Movement with Left Ventricular Function 主动脉根部运动与左心室功能的关系
Pub Date : 2023-03-01 DOI: 10.25259/ijcdw_25_2022
Imran Shaik
The motion of structures of the heart is the basis for cardiac function. Factors such as low image quality and low signal-to-noise ratio create hindrances in the adequate valuation of left ventricular (LV) systolic and diastolic function. Even in cases with poor image quality, the aorta being a large structure is well visualized. One of the unorthodox approaches to the assessment of heart function is the study of aortic root movement.We studied patients who came to the Nizam Institute of Medical Sciences. The ethics committee of the institute approved our study. We studied 85 patients who came to the emergency or outpatient department with or without various cardiovascular problems. We have included patients who presented with myocardial infarction, arrhythmia, and heart failure, cerebrovascular accident. We measured the constants pertaining to the aortic root motion and LV function with the standard parameters of echocardiography. Then, we aimed to check for a correlation between aortic root movement parameters and the LV function of the heart. Patients filling the inclusion criteria were enrolled in the study after taking informed consent. The data from the participants were collected prospectively. We recorded the echocardiography according to the standard guidelines. We used the Vivid E9 scanner (GE Vingmed Ultrasound AS) with the M5S-D (1.7–3.3 MHz) cardiac probe to acquire the data. We studied the echocardiographic 2D images and Doppler parameters. We used the parasternal long axis view as well as the parasternal short axis view to measure the aortic movement.We included a total number of 85 patients as per the defined criteria among which 22 (25.88%) are females and 63 (74.11%) are males. The average age of enrolled participants was 56.30 years (±14.95 years). The mean age of the patients was 56.3 ± 14.9. About 75% of the subjects had LV dysfunction and the remaining had normal lv function. Sixty-five patients had LV dysfunction either due to ischemic or non-ischemic cardiomyopathy. We, then, checked for the relationship between the aortic root constants and the LV function parameters. We found the mean value of aortic root diastolic distance (ARDD) as 2.59 ± 0.43 cm and. The aortic root maximal diastolic velocity (ARDV) was 10.8 ± 2.4 cm/s. The aortic root systolic distance (ARSD) was 2.71 ± 0.65 cm. The aortic root maximal systolic velocity (ARSV) was 7.92 ± 2.26 cm/s. Mean aortic root excursion was 4.3 mm. Aortic root systolic excursion (ARSE) showed a parallel relation with LV function (r up to 0.7). We found ARSD and ARSV correlating weakly with systolic Doppler parameters, such as ejection fraction (EF), maximum annular plane systolic excursion (MAPSE), and s' medial. ARSE was an exception that it showed a good correlation with s’medial r = 0.746 (P < 0.001), EF r = 0.807 (P < 0.001), and MAPSE r = 0.68 (P < 0.001). The ARDD and ARDV related poorly with LV diastolic parameters such as e' mean, e' medial, e' lateral, E/A, an
心脏结构的运动是心脏功能的基础。低图像质量和低信噪比等因素阻碍了左心室收缩和舒张功能的充分评估。即使在图像质量较差的情况下,主动脉作为一个大结构也能很好地显示。评估心脏功能的非正统方法之一是主动脉根部运动的研究。我们研究了来到尼扎姆医学科学研究所的病人。研究所的伦理委员会批准了我们的研究。我们研究了85名来到急诊科或门诊部的患者,他们有或没有各种心血管问题。我们纳入了表现为心肌梗死、心律失常、心力衰竭、脑血管意外的患者。我们用超声心动图的标准参数测量了主动脉根部运动和左室功能的相关常数。然后,我们的目的是检查主动脉根部运动参数与心脏左室功能之间的相关性。符合纳入标准的患者在知情同意后被纳入研究。参与者的数据是前瞻性收集的。我们按照标准指南记录超声心动图。我们使用Vivid E9扫描仪(GE Vingmed Ultrasound AS)和M5S-D (1.7-3.3 MHz)心脏探头采集数据。我们研究了超声心动图二维图像和多普勒参数。我们使用胸骨旁长轴位和胸骨旁短轴位来测量主动脉运动。我们共纳入85例患者,其中女性22例(25.88%),男性63例(74.11%)。参与者的平均年龄为56.30岁(±14.95岁)。患者平均年龄56.3±14.9岁。约75%的受试者存在左室功能障碍,其余受试者左室功能正常。65例患者因缺血性或非缺血性心肌病出现左室功能障碍。然后,我们检查了主动脉根部常数与左室功能参数之间的关系。主动脉根舒张距离(ARDD)均值为2.59±0.43 cm;主动脉根部最大舒张速度(ARDV)为10.8±2.4 cm/s。主动脉根收缩距离(ARSD)为2.71±0.65 cm。主动脉根部最大收缩速度(ARSV)为7.92±2.26 cm/s。平均主动脉根部偏移4.3 mm。主动脉根收缩偏移(Aortic root systolic excursion, ARSE)与左室功能呈平行关系(r > 0.7)。我们发现ARSD和ARSV与收缩期多普勒参数,如射血分数(EF)、最大环面收缩偏移(MAPSE)和s'内侧相关性较弱。ass是一个例外,它与s 'medial r = 0.746 (P < 0.001), EF r = 0.807 (P < 0.001), MAPSE r = 0.68 (P < 0.001)表现出良好的相关性。ARDD和ARDV与左室舒张参数如e′均值、e′内侧、e′外侧、e /A和e /e′相关性较差。E速度、E/A、E/ E均值与ARDV呈负相关。ARDD (r > 0.02)和ARSD (r均< 0.40)与左室多普勒测量结果无关。ARDV与部分左室舒张多普勒参数相关(r > 0.51), ARSV仅与二尖瓣环平面收缩偏移相关(r = 0.31)。事实上,我们发现与多普勒测量相比,ARDD与ARDV的相关性更好。在我们的研究中,我们纳入了有心血管疾病的受试者,我们得出结论,收缩期主动脉根部运动与收缩期左室功能显著相关,最重要的是主动脉根部收缩速度。我们发现舒张根运动参数与舒张期左室功能相关性较弱。在回声窗差的患者中,主动脉根部运动可能有助于预测伴有或不伴有左室功能障碍的患者的左室功能。
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Indian journal of cardiovascular disease in women WINCARS
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