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Acute Diagnosis of Wilson’s Disease in a Teenage Patient 1例青少年威尔森氏病的急性诊断
Pub Date : 2019-10-31 DOI: 10.33470/2379-9536.1242
Sarah Irvin, R. McCarthy
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引用次数: 1
Extending Our Reach: Looking to the Future for the Marshall Journal of Medicine 扩大我们的影响范围:展望马歇尔医学杂志的未来
Pub Date : 2019-07-31 DOI: 10.33470/2379-9536.1237
D. Shah
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引用次数: 0
Availability of Long Acting Reversible Contraceptives for Adolescents in Urban vs Rural West Virginia Counties 西弗吉尼亚州城乡青少年长效可逆避孕药具的可得性
Pub Date : 2019-07-31 DOI: 10.33470/2379-9536.1228
B. Andrews, C. Ross, J. Yoost
The study objective was to evaluate long acting reversible contraceptive (LARC) method availability and access for adolescents in rural and urban counties in West Virginia (WV). A cross-sectional survey of Title X family planning providers throughout WV was conducted from January 2016 to July 2017. This survey was sent to 226 family planning providers in WV to assess patterns of LARC availability. The survey assessed provider training level, LARC services provided and frequency, clinical practice, referral patterns, and comfort level providing adolescent LARC services. Survey results were analyzed by providers’ rural vs urban status, based on US census county codes. Survey responses yielded 127 total responders, 65 (51.2%) were urban, and the remaining 62 (48.8%), were rural. Urban providers had a larger representation of medical doctors, while rural providers were primarily nurse practitioners (p<0.001). Intrauterine devices (IUD) had lower availability with rural providers (p<0.006). Years of experience doing IUD placement (p<0.010), frequency of placing implants (p<0.010), and frequency placing implants in teenagers (p<0.012) were significantly less in rural providers. This survey showed significant differences in practice between urban and rural settings including training, experience, contraceptive options, barriers to care, and practice guidelines.
本研究的目的是评估西弗吉尼亚州农村和城市县青少年长效可逆避孕(LARC)方法的可得性和可及性。2016年1月至2017年7月,对整个西弗吉尼亚州的第十章计划生育提供者进行了横断面调查。这项调查被发送给WV的226个计划生育提供者,以评估LARC的可用性模式。调查评估了提供者的培训水平、提供的LARC服务和频率、临床实践、转诊模式和青少年LARC服务的舒适度。根据美国人口普查局的县代码,对调查结果进行了农村和城市状况的分析。共有127名应答者,其中65名(51.2%)来自城市,其余62名(48.8%)来自农村。城市提供者有更多的医生代表,而农村提供者主要是执业护士(p<0.001)。农村地区提供的宫内节育器(IUD)可得性较低(p<0.006)。农村医生的人工节育器放置年限(p<0.010)、植入频率(p<0.010)和青少年植入频率(p<0.012)明显低于农村医生。这项调查显示,城市和农村在培训、经验、避孕选择、护理障碍和实践指南等方面存在显著差异。
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引用次数: 3
How acceptable is the HIV/AIDS self-testing among women attending immunization clinics in Effurun, Southern Nigeria 在尼日利亚南部Effurun的免疫接种诊所接受艾滋病毒/艾滋病自我检测的程度如何
Pub Date : 2019-07-31 DOI: 10.33470/2379-9536.1225
W. Adebimpe, D. Ebikeme, O. Omobuwa, E. Oladejo
HIV testing remains the gateway to HIV/AIDS prevention, treatment, care and support interventions. In Nigeria, a significant proportion of the populations do not know their HIV status. HIV self-testing done without the help of a healthcare provider could remove identified barriers to HIV testing and close gaps in HIV treatment and prevention cascades. This study set out to assess the knowledge and acceptability of HIV self-testing (HIVST) among women of child bearing age attending immunization clinics in Effurun, Nigeria. A descriptive, crosssectional study was conducted among 357 women of child-bearing age selected using multistage sampling technique. Research instrument used was a semi-structured, interviewer-administered pre-tested questionnaire. Data was analyzed using the SPSS software version 23.0. Mean age of respondents was 33.6 (±7.3) years. Of the respondents, 286 (80.1%) were aware of HIV self testing; electronic media followed by health care workers were the common sources of information. About 83 (23.0%) had good while 274 (76.8%) had poor mean knowledge score of HIVST. Two hundred and seventy eight (77.9%) ever thought one could do the HIV test at home by oneself, 306 (86.0%) accepted to conduct the test on themselves if they had the opportunity while 51 (14.0%) said they would not. On binary logistic regression, identified predictors of accepting HIVST among the respondents included being older, educated, and married. It was concluded that a high knowledge level and acceptability of HIVST among the study respondents lends support to the fact that that the procedure should be promoted in the stakeholders’ efforts to improve HIV testing among the general population.
艾滋病毒检测仍然是艾滋病毒/艾滋病预防、治疗、护理和支持干预措施的门户。在尼日利亚,相当一部分人口不知道自己的艾滋病毒状况。在没有医疗保健提供者帮助的情况下进行艾滋病毒自我检测可以消除已确定的艾滋病毒检测障碍,并缩小艾滋病毒治疗和预防方面的差距。这项研究旨在评估在尼日利亚埃富伦的免疫诊所就诊的育龄妇女对艾滋病毒自我检测(HIVST)的了解和可接受性。采用多阶段抽样技术对357名育龄妇女进行了描述性横断面研究。所使用的研究工具是一份半结构化的、由面试官管理的预测试问卷。数据采用SPSS 23.0版软件进行分析。受访者的平均年龄为33.6(±7.3)岁。在受访者中,286人(80.1%)知道艾滋病毒自我检测;电子媒体和卫生保健工作者是常见的信息来源。约83人(23.0%)的HIVST平均知识得分良好,274人(76.8%)的平均知识得分较差。278人(77.9%)曾认为自己可以在家里进行艾滋病毒检测,306人(86.0%)接受了如果有机会的话自己进行检测,51人(14.0%)表示不会。在二元逻辑回归中,确定的受访者接受HIVST的预测因素包括年龄较大、受过教育和已婚。研究得出的结论是,研究受访者对HIVST的高知识水平和可接受性支持了这样一个事实,即在利益相关者努力改善普通人群中的HIV检测时,应推广该程序。
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引用次数: 1
Giving hope: best healing power in medicine 给予希望:医学最好的治愈力量
Pub Date : 2019-07-31 DOI: 10.33470/2379-9536.1239
N. Zgheib
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引用次数: 0
Group A Streptococcus Brain Abscess in a Patient on Adalimumab Therapy 阿达木单抗治疗患者的A组链球菌脑脓肿
Pub Date : 2019-07-31 DOI: 10.33470/2379-9536.1230
R. Carroll, A. Abu-Hashyeh, J. Gainer, Kara S. Willenburg, Charles Meadows
Brain abscesses represent a group of dangerous infections typically caused by a number of classic organisms. Group A streptococcus is a rare cause of brain abscesses and those patients that do have this particular condition will typically have a distal source of infection. We present a case of patient with a biopsy confirmed group A streptococcal without a distal source of infection. His only identifiable risk factor was his adalimumab therapy for ankylosing spondylitis. While adalimumab has not been linked to streptococcal infection in the past, it has been associated with multiple atypical infections and some of the consequences of its mechanism as a tissue necrosis factor alpha inhibitor can theoretically predispose patients to streptococcal infection when considered in conjunction with known streptococcal virulence factors. This case raises the question of whether the patient’s adalimumab therapy may have contributed to his unusual presentation of streptococcal infection and prompts further consideration and study of the risks of adalimumab and other similar immunosuppressant monoclonal antibodies.
脑脓肿代表了一组危险的感染,通常由许多经典的生物体引起。A组链球菌是脑脓肿的一种罕见原因,那些患有这种特殊疾病的患者通常会有远端感染源。我们报告了一例经活检证实为a组链球菌且无远端感染源的患者。他唯一可识别的风险因素是阿达木单抗治疗强直性脊柱炎。虽然阿达木单抗过去没有与链球菌感染有关,但它与多种非典型感染有关,其作为组织坏死因子α抑制剂的机制的一些后果在理论上与已知的链球菌毒力因子一起考虑时,会使患者易患链球菌感染。该病例引发了一个问题,即患者的阿达木单抗治疗是否可能导致了其链球菌感染的异常表现,并促使人们进一步考虑和研究阿达木单抗和其他类似免疫抑制剂单克隆抗体的风险。
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引用次数: 0
The Challenge of Electronic Cigarettes 电子烟的挑战
Pub Date : 2019-07-31 DOI: 10.33470/2379-9536.1231
Sutoidem Akpanudo
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引用次数: 5
Incidental Retroperitoneal Castleman’s Disease Found in Patient with Renal Cell Carcinoma: a case report 肾细胞癌并发腹膜后Castleman病1例报告
Pub Date : 2019-07-31 DOI: 10.33470/2379-9536.1226
S. Richardson, J. Jensen, N. Nahar, N. Zgheib
Samantha Richardson, James Jensen, Niru Nahar, and Nadim Bou Zgheib Author Affiliations Samantha Richardson (Marshall University Joan C. Edwards School of Medicine, Huntington, West Virginia) James Jensen (Marshall University Joan C. Edwards School of Medicine, Huntington, West Virginia) Niru Nahar (Marshall University Joan C. Edwards School of Medicine, Huntington, West Virginia) Nadim Bou Zgheib (Marshall University Joan C. Edwards School of Medicine, Huntington, West Virginia)
Samantha Richardson、James Jensen、Niru Nahar和Nadim Bou Zgheib作者关系Samantha理查德森(西弗吉尼亚州亨廷顿市马歇尔大学Joan C.Edwards医学院)James Jensen。爱德华医学院,西弗吉尼亚州亨廷顿)Nadim Bou Zgheib(马歇尔大学Joan C.Edwards医学院,弗吉尼亚州亨廷顿市)
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引用次数: 0
Prasugrel Inappropriate Use in Patients Post-percutaneous coronary intervention (PCI). A Single Center Study 普拉格雷在经皮冠状动脉介入治疗(PCI)后患者中的不当使用。单中心研究
Pub Date : 2019-07-31 DOI: 10.33470/2379-9536.1220
A. Amro, Kanaan Mansoor, M. Amro, A. Sobeih, Obadah Aqtash, H. Hirzallah, Alaa Gabi, M. Urella, W. Ahmed, Sandra Shenouda, R. Sayyed
Prasugrel is a thienopyridine that was approved by the US Food and Drug Administration in combination with aspirin for the reduction of thrombotic events as well as stent thrombosis in patients with acute coronary syndrome who undergo percutaneous coronary intervention. This retrospective study aims to assess the frequency of inappropriate use of prasugrel and to emphasize that prasugrel still needs more attention as inappropriate use may result in significant morbidity.
Prasugrel是一种噻吩吡啶,已被美国食品和药物管理局(fda)批准与阿司匹林联合使用,用于减少急性冠状动脉综合征患者经皮冠状动脉介入治疗后的血栓形成事件和支架血栓形成。本回顾性研究旨在评估普拉格雷不当使用的频率,并强调普拉格雷仍然需要更多的关注,因为不当使用可能导致显著的发病率。
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引用次数: 0
Intralesional Corticosteroids for Long-term Control of Primary Cutaneous Marginal Zone Lymphoma without systemic involvement 病灶内皮质类固醇对无全身受累的原发性皮肤边缘区淋巴瘤的长期控制
Pub Date : 2019-07-31 DOI: 10.33470/2379-9536.1216
P. Tiwari, John C. Hall, Anand Rajpara, Carol W Stanford, D. Aires
Primary cutaneous marginal zone lymphoma (PCMZL) is a B cell lymphoma with a very low metastatic rate. Radiographic monitoring for internal involvement may be indicated initially. Favored treatments include radiation and excision. Radiation has high risk of local recurrence. Excision carries risk of infection and scarring. We report successful long-term treatment of recurrent PCMZL via intralesional steroid injections into new lesions as they arose. This was preferred by the patient over her prior radiation and surgical treatments. Intralesional steroids have the advantages of being simple and well tolerated, without exposure to ionizing radiation or to the infection and scarring associated with surgery.
原发性皮肤边缘区淋巴瘤(PCMZL)是一种转移率极低的B细胞淋巴瘤。内部介入的射线照相监测可在最初指示。常用的治疗方法包括放疗和切除术。辐射局部复发的风险很高。切除会带来感染和疤痕的风险。我们报告了复发性PCMZL的成功长期治疗,方法是在新病变出现时向其注射类固醇。与之前的放射治疗和手术治疗相比,患者更喜欢这种方法。病灶内类固醇具有简单且耐受性好的优点,不会暴露于电离辐射或与手术相关的感染和疤痕。
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Marshall journal of medicine
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