Pub Date : 2023-04-29DOI: 10.33696/gynaecology.4.041
M. Di Silvio, J. E. Luján-Irastorza, C. Durand-Montaño, Roberto Henández-Ramos, J. Barrón-Vallejo, Daniela Ávila-Rebollar, Julio Myslabodski, Maruxa Pariente-Fernández, Jorge Mario Tagle-Rodríguez, Miguel Ángel Ramírez-Amezcua, María Angélica Paredes-Núñez, V. Vargas-Hernández
Objective: To describe the evolution of Utero-Vesical Fistula (UVF) of one patient who received conservative treatment using intravenous (IV) infusion of 120x106 Adipose tissue Mesenchymal Stem Cells (ADMSCs). Clinical case report: A 36-year-old female presented with postcesarean hematuria 3 hours after an emergency c-section was performed consequently to placental abruption during labor. The primary measure was to use a transurethral Silastic 18F Foley catheter to prevent bladder expansion. The catheter remained for 21 days. Evaluation through Computerized Tomography Cystography (Cysto-CT) revealed failure to close the fistula. The decision to inject ADMSCs as an IV single dose was done. Three weeks after this intervention no blood was seen in the urine drainage bag. Complete resolution of UVF was confirmed with a control CT urogram. Result: Total closure of UVF. Conclusions: The IV infusion of ADMSCs proved to be a plausible and effective conservative treatment of UVF.
{"title":"Utero-Vesical Fistula Closure after 3 Weeks Treatment with Intravenous Mesenchymal Stem Cells Infusion: Case Report","authors":"M. Di Silvio, J. E. Luján-Irastorza, C. Durand-Montaño, Roberto Henández-Ramos, J. Barrón-Vallejo, Daniela Ávila-Rebollar, Julio Myslabodski, Maruxa Pariente-Fernández, Jorge Mario Tagle-Rodríguez, Miguel Ángel Ramírez-Amezcua, María Angélica Paredes-Núñez, V. Vargas-Hernández","doi":"10.33696/gynaecology.4.041","DOIUrl":"https://doi.org/10.33696/gynaecology.4.041","url":null,"abstract":"Objective: To describe the evolution of Utero-Vesical Fistula (UVF) of one patient who received conservative treatment using intravenous (IV) infusion of 120x106 Adipose tissue Mesenchymal Stem Cells (ADMSCs). Clinical case report: A 36-year-old female presented with postcesarean hematuria 3 hours after an emergency c-section was performed consequently to placental abruption during labor. The primary measure was to use a transurethral Silastic 18F Foley catheter to prevent bladder expansion. The catheter remained for 21 days. Evaluation through Computerized Tomography Cystography (Cysto-CT) revealed failure to close the fistula. The decision to inject ADMSCs as an IV single dose was done. Three weeks after this intervention no blood was seen in the urine drainage bag. Complete resolution of UVF was confirmed with a control CT urogram. Result: Total closure of UVF. Conclusions: The IV infusion of ADMSCs proved to be a plausible and effective conservative treatment of UVF.","PeriodicalId":93076,"journal":{"name":"Archives of obstetrics and gynaecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46839442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-29DOI: 10.33696/gynaecology.4.042
F. Bouguerra, E. Boudhina, H. Chahdoura, M. Souissi, S. Tbessi, N. Bouzid, S. Belajouza, S. Tebra
Background: Ovarian cysts are usually treated using medical or surgical interventions. However, in some cases, these treatments may not be feasible or effective, and alternative options need to be considered. Case presentation: We report a case of a 43-year-old woman with a history of recurrent hemorrhagic ovarian cysts, who was on anticoagulant therapy due to tight mitral stenosis and had multiple autoimmune disorders. Surgical castration was not a viable option due to the bleeding risk, and intramuscular injection of analogues was not preferred. Therefore, external ovarian radiotherapy for hemostasis was planned. Conclusion: Our case highlights that external ovarian radiotherapy can be an effective option for hemostasis in patients with bleeding ovarian cysts, especially when other treatments are contraindicated or have failed.
{"title":"Hemostatic Pelvic Irradiation: A Rarely Reported Approach to Benign Gynecological Bleeding","authors":"F. Bouguerra, E. Boudhina, H. Chahdoura, M. Souissi, S. Tbessi, N. Bouzid, S. Belajouza, S. Tebra","doi":"10.33696/gynaecology.4.042","DOIUrl":"https://doi.org/10.33696/gynaecology.4.042","url":null,"abstract":"Background: Ovarian cysts are usually treated using medical or surgical interventions. However, in some cases, these treatments may not be feasible or effective, and alternative options need to be considered.\u0000\u0000Case presentation: We report a case of a 43-year-old woman with a history of recurrent hemorrhagic ovarian cysts, who was on anticoagulant therapy due to tight mitral stenosis and had multiple autoimmune disorders. Surgical castration was not a viable option due to the bleeding risk, and intramuscular injection of analogues was not preferred. Therefore, external ovarian radiotherapy for hemostasis was planned.\u0000\u0000Conclusion: Our case highlights that external ovarian radiotherapy can be an effective option for hemostasis in patients with bleeding ovarian cysts, especially when other treatments are contraindicated or have failed.","PeriodicalId":93076,"journal":{"name":"Archives of obstetrics and gynaecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44812103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-29DOI: 10.33696/gynaecology.4.040
Olubunmi Ogein, Adeyemi A Okunowo, G. Olorunfemi, Benedetto Osunwusi, O. Adegbola
Background: Preterm birth is one of the major causes of neonatal morbidity and mortality worldwide. The association between occurrence of preterm birth and biomarkers measured in the maternal serum maybe helpful in predicting preterm birth especially in low resource settings. Aim: We aimed to examine the association between maternal serum leptin level and occurrence of preterm birth. Materials and Methods: This was an analytical cross-sectional study of women with preterm and term births in Lagos, Nigeria. One hundred and ninety women comprising of 95 women with preterm and term births respectively recruited. Maternal serum leptin levels were determined using Enzyme-linked immunosorbent assay (ELISA) technique. Data was analyzed by Stata version 16 (StataCorp, USA) statistical software with significance level set at p-value <0.05. Results: The mean serum leptin levels were significantly lower in women with preterm delivery compared to women with term delivery (1.48 ng/ml ± 0.72 vs. 1.75 ng/ml ± 0.67, p-value=0.007). On further analysis, women with very preterm birth had significantly lower serum leptin levels compared with women with moderate to late preterm and term births (1.28 ± 0.73 vs 1.55 ± 0.70 vs 1.75ng/ml ± 0.67, p-value=0.006). There was 57% reduction in the odds of having preterm delivery for every unit increase in serum leptin level on multivariate analysis (adjusted OR: 0.43, 95%CI: 0.26 – 0.71, P-value=0.001). Conclusion: Serum leptin concentration was significantly lower in women who had preterm births compared to women who had term births. Longitudinal studies are required to determine the predictive value of maternal serum leptin level with regards to preterm birth.
背景:早产是全世界新生儿发病和死亡的主要原因之一。早产发生与母体血清中测量的生物标志物之间的关联可能有助于预测早产，特别是在资源匮乏的环境中。目的:探讨孕妇血清瘦素水平与早产发生的关系。材料和方法:这是一项对尼日利亚拉各斯早产和足月妇女的分析性横断面研究。共招募了190名妇女，其中95名早产妇女和95名足月分娩妇女。采用酶联免疫吸附法(ELISA)检测孕妇血清瘦素水平。数据分析采用Stata version 16 (StataCorp, USA)统计软件，显著性水平设为p值<0.05。结果:早产妇女的平均血清瘦素水平明显低于足月分娩妇女(1.48 ng/ml±0.72 vs. 1.75 ng/ml±0.67,p值=0.007)。进一步分析，重度早产妇女的血清瘦素水平明显低于中度至晚期早产和足月分娩妇女(1.28±0.73 vs 1.55±0.70 vs 1.75ng/ml±0.67,p值=0.006)。多因素分析显示，血清瘦素水平每升高一个单位，早产的几率降低57%(校正OR: 0.43, 95%CI: 0.26 - 0.71, p值=0.001)。结论:早产妇女的血清瘦素浓度明显低于足月分娩妇女。需要进行纵向研究来确定母亲血清瘦素水平对早产的预测价值。
{"title":"Association between Maternal Serum Leptin Level and Preterm Birth among Parturients in Lagos, Nigeria","authors":"Olubunmi Ogein, Adeyemi A Okunowo, G. Olorunfemi, Benedetto Osunwusi, O. Adegbola","doi":"10.33696/gynaecology.4.040","DOIUrl":"https://doi.org/10.33696/gynaecology.4.040","url":null,"abstract":"Background: Preterm birth is one of the major causes of neonatal morbidity and mortality worldwide. The association between occurrence of preterm birth and biomarkers measured in the maternal serum maybe helpful in predicting preterm birth especially in low resource settings.\u0000\u0000Aim: We aimed to examine the association between maternal serum leptin level and occurrence of preterm birth.\u0000\u0000Materials and Methods: This was an analytical cross-sectional study of women with preterm and term births in Lagos, Nigeria. One hundred and ninety women comprising of 95 women with preterm and term births respectively recruited. Maternal serum leptin levels were determined using Enzyme-linked immunosorbent assay (ELISA) technique. Data was analyzed by Stata version 16 (StataCorp, USA) statistical software with significance level set at p-value <0.05.\u0000\u0000Results: The mean serum leptin levels were significantly lower in women with preterm delivery compared to women with term delivery (1.48 ng/ml ± 0.72 vs. 1.75 ng/ml ± 0.67, p-value=0.007). On further analysis, women with very preterm birth had significantly lower serum leptin levels compared with women with moderate to late preterm and term births (1.28 ± 0.73 vs 1.55 ± 0.70 vs 1.75ng/ml ± 0.67, p-value=0.006). There was 57% reduction in the odds of having preterm delivery for every unit increase in serum leptin level on multivariate analysis (adjusted OR: 0.43, 95%CI: 0.26 – 0.71, P-value=0.001).\u0000\u0000Conclusion: Serum leptin concentration was significantly lower in women who had preterm births compared to women who had term births. Longitudinal studies are required to determine the predictive value of maternal serum leptin level with regards to preterm birth.","PeriodicalId":93076,"journal":{"name":"Archives of obstetrics and gynaecology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69669995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-29DOI: 10.33696/gynaecology.4.043
Li Juan Sun, Shan Shan Liang, Min Hao Liu, Jia Ping Pan, Mei Yuan Huang, Xiao Ming Teng, Hai Xia Wu
Objective: The aim of this study was to investigate the efficacy and safety of early cumulus cell removal (ECCR) during human in vitro fertilization (IVF). Methods: A retrospective analysis was performed between January 2011 and December 2019. The study enrolled 1,131 couples who underwent IVF treatment with ECCR. After propensity score matching at a 1:1 ratio, 1,131 couples who underwent overnight coincubation of gametes were selected. The main outcome measure was the cumulative live birth rate. Secondary outcome measures included the cumulative pregnancy rate, polyspermy rate, available embryo rate, miscarriage rate, malformation rate, time to live birth, and oocyte-to-baby rate. Results: There were no significant differences found between the two groups in the polyspermy rate, available embryo rate, miscarriage rate, time to live birth, oocyte-to-baby rate, and neonatal congenital anomalies rate. The results of the study showed that ECCR was associated with a significantly higher cumulative live birth rate and cumulative pregnancy rate, along with a significantly lower fertilization rate. Conclusion: ECCR tended to confer increased cumulative live birth rate and had no negative effect on the neonatal malformation rate.
{"title":"Early Cumulus Cell Removal Increases Cumulative Live Birth Rate while Having No Negative Effect on the Malformation Rate in In vitro Fertilization: A Propensity Score-Matched Cohort Study","authors":"Li Juan Sun, Shan Shan Liang, Min Hao Liu, Jia Ping Pan, Mei Yuan Huang, Xiao Ming Teng, Hai Xia Wu","doi":"10.33696/gynaecology.4.043","DOIUrl":"https://doi.org/10.33696/gynaecology.4.043","url":null,"abstract":"Objective: The aim of this study was to investigate the efficacy and safety of early cumulus cell removal (ECCR) during human in vitro fertilization (IVF). Methods: A retrospective analysis was performed between January 2011 and December 2019. The study enrolled 1,131 couples who underwent IVF treatment with ECCR. After propensity score matching at a 1:1 ratio, 1,131 couples who underwent overnight coincubation of gametes were selected. The main outcome measure was the cumulative live birth rate. Secondary outcome measures included the cumulative pregnancy rate, polyspermy rate, available embryo rate, miscarriage rate, malformation rate, time to live birth, and oocyte-to-baby rate. Results: There were no significant differences found between the two groups in the polyspermy rate, available embryo rate, miscarriage rate, time to live birth, oocyte-to-baby rate, and neonatal congenital anomalies rate. The results of the study showed that ECCR was associated with a significantly higher cumulative live birth rate and cumulative pregnancy rate, along with a significantly lower fertilization rate. Conclusion: ECCR tended to confer increased cumulative live birth rate and had no negative effect on the neonatal malformation rate.","PeriodicalId":93076,"journal":{"name":"Archives of obstetrics and gynaecology","volume":"240 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135846965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-28DOI: 10.33696/gynaecology.4.039
Sevcan Sarıkaya, E. Uysal, O. Günenç
Objective: The aim of this study was to predict the selection of treatment for ectopic pregnancy (EP) using the values of platelet/lymphocyte ratio (PLR), neutrophil/lymphocyte ratio (NLR), monocyte/lymphocyte ratio (MLR) and systemic immune inflammation index (SII) obtained from hematological parameters routinely used in clinical practice. Design: Retrospective observational study. Place & duration of study: This retrospective, cross-sectional study was conducted in the Department of Obstetrics and Gynecology of Konya City Hospital, between August 2020 and August 2022. Methodology: The study included 140 patients who were diagnosed with EP in our hospital. The patients were separated as those who received medical treatment with methotrexate (MTX) (Group I) and those who underwent surgical procedures (Group II). The two groups were compared with respect to demographic characteristics and pre-treatment laboratory parameters. Results: Of the 140 patients diagnosed with EP, 75 were in Group I, treated with MTX, and 65 were in Group II, treated with surgery. No significant difference was determined between the groups with respect to age, body mass index, and gravida-parity of the patients (p>0.05). The incidence of extrauterine mass, presence of yolk sac, and fetal heartbeat on ultrasonography was significantly higher in Group II than in Group I (p<0.05). NLR and MLR values in Group II were significantly lower than in Group I (p<0.05). The PLR value did not differ significantly between the groups (p>0.05). The SII value was significantly higher in Group II than in Group I (p<0.05). Conclusion: NLR and MLR were found to be lower, and the SII was significantly higher in the patients who underwent surgery. Hematological parameters, especially SII, are potential markers that can be used in EP treatment selection.
{"title":"Can the Systemic Immune Inflammation Index Predict the Treatment of Ectopic Pregnancy?","authors":"Sevcan Sarıkaya, E. Uysal, O. Günenç","doi":"10.33696/gynaecology.4.039","DOIUrl":"https://doi.org/10.33696/gynaecology.4.039","url":null,"abstract":"Objective: The aim of this study was to predict the selection of treatment for ectopic pregnancy (EP) using the values of platelet/lymphocyte ratio (PLR), neutrophil/lymphocyte ratio (NLR), monocyte/lymphocyte ratio (MLR) and systemic immune inflammation index (SII) obtained from hematological parameters routinely used in clinical practice.\u0000\u0000Design: Retrospective observational study.\u0000\u0000Place & duration of study: This retrospective, cross-sectional study was conducted in the Department of Obstetrics and Gynecology of Konya City Hospital, between August 2020 and August 2022.\u0000\u0000Methodology: The study included 140 patients who were diagnosed with EP in our hospital. The patients were separated as those who received medical treatment with methotrexate (MTX) (Group I) and those who underwent surgical procedures (Group II). The two groups were compared with respect to demographic characteristics and pre-treatment laboratory parameters.\u0000\u0000Results: Of the 140 patients diagnosed with EP, 75 were in Group I, treated with MTX, and 65 were in Group II, treated with surgery. No significant difference was determined between the groups with respect to age, body mass index, and gravida-parity of the patients (p>0.05). The incidence of extrauterine mass, presence of yolk sac, and fetal heartbeat on ultrasonography was significantly higher in Group II than in Group I (p<0.05). NLR and MLR values in Group II were significantly lower than in Group I (p<0.05). The PLR value did not differ significantly between the groups (p>0.05). The SII value was significantly higher in Group II than in Group I (p<0.05).\u0000\u0000Conclusion: NLR and MLR were found to be lower, and the SII was significantly higher in the patients who underwent surgery. Hematological parameters, especially SII, are potential markers that can be used in EP treatment selection.","PeriodicalId":93076,"journal":{"name":"Archives of obstetrics and gynaecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49122279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-06DOI: 10.33696/gynaecology.4.037
Ana Carolina Sater, R. Nisihara, Danielle Medeiros Teixeira Miyague, A. Schuffner, A. H. Miyague
Purpose: The increase in infertility around the world has a negative impact on sexual desire and function. The objective of this study was to evaluate the presence of sexual dysfunction in women diagnosed with infertility, comparing them with healthy controls. Methods: This is a cross-sectional study based on online questionnaire. Infertile women and healthy controls filled a questionnaire about epidemiological and assisted reproduction data. The infertile patients answered the Female Sexual Function Index (FSFI) and the Short-Form Health Survey (SF-12) questionnaires to assess sexual performance, physical, and mental health. The control group answered only to the FSFI. Results: The survey was completed by 357 subjects: 157 infertility patients and 200 matched controls. All medians of the FSFI domains of patients in the infertility group are lower (p=0.036) when compared to controls, especially the scores in the arousal and lubrication domains (p=0.003 and p<0.0001, respectively). In this group, most are in good physical health and half are in good mental health. The depression rate was 12.7%. Patients who have depression have worse FSFI scores (p=0.009). Depression and sexual dysfunction were experienced by 27.4% (n=17) patients (p<0.0001). Worse mental health was related to patients at higher risk for sexual dysfunction (p<0.0001). Conclusion: In our sample of women undergoing infertility treatment, we found that the FSFI scores were significantly lower than in the control group, mainly in the arousal and lubrication domains. Additionally, it was found that the worse the mental health, the greater the possibility of sexual dysfunction in this group.
{"title":"Evaluation of Sexual Dysfunction in Brazilian Women with Infertility Undergoing Assisted Reproduction Treatment","authors":"Ana Carolina Sater, R. Nisihara, Danielle Medeiros Teixeira Miyague, A. Schuffner, A. H. Miyague","doi":"10.33696/gynaecology.4.037","DOIUrl":"https://doi.org/10.33696/gynaecology.4.037","url":null,"abstract":"Purpose: The increase in infertility around the world has a negative impact on sexual desire and function. The objective of this study was to evaluate the presence of sexual dysfunction in women diagnosed with infertility, comparing them with healthy controls.\u0000\u0000Methods: This is a cross-sectional study based on online questionnaire. Infertile women and healthy controls filled a questionnaire about epidemiological and assisted reproduction data. The infertile patients answered the Female Sexual Function Index (FSFI) and the Short-Form Health Survey (SF-12) questionnaires to assess sexual performance, physical, and mental health. The control group answered only to the FSFI.\u0000\u0000Results: The survey was completed by 357 subjects: 157 infertility patients and 200 matched controls. All medians of the FSFI domains of patients in the infertility group are lower (p=0.036) when compared to controls, especially the scores in the arousal and lubrication domains (p=0.003 and p<0.0001, respectively). In this group, most are in good physical health and half are in good mental health. The depression rate was 12.7%. Patients who have depression have worse FSFI scores (p=0.009). Depression and sexual dysfunction were experienced by 27.4% (n=17) patients (p<0.0001). Worse mental health was related to patients at higher risk for sexual dysfunction (p<0.0001).\u0000\u0000Conclusion: In our sample of women undergoing infertility treatment, we found that the FSFI scores were significantly lower than in the control group, mainly in the arousal and lubrication domains. Additionally, it was found that the worse the mental health, the greater the possibility of sexual dysfunction in this group.","PeriodicalId":93076,"journal":{"name":"Archives of obstetrics and gynaecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45058044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-06DOI: 10.33696/gynaecology.4.036
Timothy J Hardy
Background and aims: Use of platelet-rich plasma (PRP) is well established in treatment of orthopedic patients. This pilot study aims to determine the efficacy of using instillation of PRP paired with hydrodistention of the bladder to treat patients with interstitial cystitis (IC). Methods: Patients with a diagnosis of interstitial cystitis were recruited to this study. Patients completed Pelvic Pain and Urgency/Frequency (PUF) patient symptom scale, which quantified a symptom and bother score. Patients were treated with hydrodistention with instillation of PRP. Patients completed the PUF questionnaire weekly for six weeks following treatment. Results: 12 patients underwent hydrodistention with instillation of PRP. The patients were all women, ranging in age from 23 to 71. The mean symptom score went from 13.167 to 7.417 and the mean bother score decreased from 6.833 to 4.41, showing a statistically significant reduction in symptom and bother scores. Conclusions: Hydrodistention with instillation of PRP is an effective treatment of interstitial cystitis.
{"title":"Novel Treatment for Interstitial Cystitis Pilot Study","authors":"Timothy J Hardy","doi":"10.33696/gynaecology.4.036","DOIUrl":"https://doi.org/10.33696/gynaecology.4.036","url":null,"abstract":"Background and aims: Use of platelet-rich plasma (PRP) is well established in treatment of orthopedic patients. This pilot study aims to determine the efficacy of using instillation of PRP paired with hydrodistention of the bladder to treat patients with interstitial cystitis (IC).\u0000\u0000Methods: Patients with a diagnosis of interstitial cystitis were recruited to this study. Patients completed Pelvic Pain and Urgency/Frequency (PUF) patient symptom scale, which quantified a symptom and bother score. Patients were treated with hydrodistention with instillation of PRP. Patients completed the PUF questionnaire weekly for six weeks following treatment.\u0000\u0000Results: 12 patients underwent hydrodistention with instillation of PRP. The patients were all women, ranging in age from 23 to 71. The mean symptom score went from 13.167 to 7.417 and the mean bother score decreased from 6.833 to 4.41, showing a statistically significant reduction in symptom and bother scores.\u0000\u0000Conclusions: Hydrodistention with instillation of PRP is an effective treatment of interstitial cystitis.","PeriodicalId":93076,"journal":{"name":"Archives of obstetrics and gynaecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45955696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-06DOI: 10.33696/gynaecology.4.038
I. Tsiaousi, M. Theodora, P. Antsaklis, A. Psarris, Michalis I. Sindos, P. Koutroumanis, Dimitrios N. Zaharakis, George Daskalakis
Objective: The present study aimed to study the vaccination acceptance of COVID-19 vaccine in the Hellenic pregnant population and make a high relative analysis of the factors that contribute to decision-making concerning the acceptance of the vaccine during pregnancy. Findings could be leveraged for improving the vaccination communication strategy to pregnant women to increase the vaccination acceptance rate. Study design: The present study is a prospective cross-sectional study conducted from October 1, 2021 until March 2022 to 800 pregnant women receiving prenatal care at a tertiary University Hospital. Data was gathered through a face-to-face questionnaire and documented via the official vaccination certificate. Results: The vaccination coverage rate was 53.9%. Employment, older age, and higher monthly income were significantly and positively associated with vaccination (p<0.001). Information provided by health professionals (p=0.004) and scientific sites (p=0.028); sufficient knowledge of vaccines were also positively related to vaccination (p<0.001); pediatric vaccination of their children in the family (p=0.003); vaccination against influenza during pregnancy (past: p<0.001 and present pregnancy: p<0.001); and vaccination against pertussis during pregnancy (present pregnancy: p<0.001) were also positively associated with vaccination. Intention to vaccinate their children in the future with all recommended vaccines; belief in the safety of the vaccines; and belief that vaccination protects children from serious diseases were positively related with vaccine acceptance. Reduced vaccination hesitancy due to the pandemic; and fear of severity of COVID-19 infection (p<0.001 in each case) associated also positively with COVID-19 vaccination. Conclusion: In conclusion we need to improve the face-to-face communication with pregnant women, focusing more on safety and effectiveness data, sharing information about surveillance programs, using clinical experience from other maternal vaccination, and presenting the benefits from vaccination to the mother and the offspring.
{"title":"COVID-19 Vaccine Acceptance during Pregnancy: Lessons Learned and How to Design the Best Strategy to Increase Vaccination Acceptance in the Future","authors":"I. Tsiaousi, M. Theodora, P. Antsaklis, A. Psarris, Michalis I. Sindos, P. Koutroumanis, Dimitrios N. Zaharakis, George Daskalakis","doi":"10.33696/gynaecology.4.038","DOIUrl":"https://doi.org/10.33696/gynaecology.4.038","url":null,"abstract":"Objective: The present study aimed to study the vaccination acceptance of COVID-19 vaccine in the Hellenic pregnant population and make a high relative analysis of the factors that contribute to decision-making concerning the acceptance of the vaccine during pregnancy. Findings could be leveraged for improving the vaccination communication strategy to pregnant women to increase the vaccination acceptance rate.\u0000\u0000Study design: The present study is a prospective cross-sectional study conducted from October 1, 2021 until March 2022 to 800 pregnant women receiving prenatal care at a tertiary University Hospital. Data was gathered through a face-to-face questionnaire and documented via the official vaccination certificate.\u0000\u0000Results: The vaccination coverage rate was 53.9%. Employment, older age, and higher monthly income were significantly and positively associated with vaccination (p<0.001). Information provided by health professionals (p=0.004) and scientific sites (p=0.028); sufficient knowledge of vaccines were also positively related to vaccination (p<0.001); pediatric vaccination of their children in the family (p=0.003); vaccination against influenza during pregnancy (past: p<0.001 and present pregnancy: p<0.001); and vaccination against pertussis during pregnancy (present pregnancy: p<0.001) were also positively associated with vaccination. Intention to vaccinate their children in the future with all recommended vaccines; belief in the safety of the vaccines; and belief that vaccination protects children from serious diseases were positively related with vaccine acceptance. Reduced vaccination hesitancy due to the pandemic; and fear of severity of COVID-19 infection (p<0.001 in each case) associated also positively with COVID-19 vaccination.\u0000\u0000Conclusion: In conclusion we need to improve the face-to-face communication with pregnant women, focusing more on safety and effectiveness data, sharing information about surveillance programs, using clinical experience from other maternal vaccination, and presenting the benefits from vaccination to the mother and the offspring.","PeriodicalId":93076,"journal":{"name":"Archives of obstetrics and gynaecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42811409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-25DOI: 10.33696/gynaecology.4.035
E. Levine, Leah Delfinado, C. Fernandez
Racial and ethnic health disparities have been identified by many information sources in recent years, and a specific example of this is severe maternal morbidity and mortality, which includes mortality from postpartum hemorrhage. It is this racial/ethnic health disparity that has been highlighted in news reports that should be of concern to all physicians and healthcare providers, recognizing that women of color have more than three times the risk of dying in childbirth than white women. The details about this are worthy of further examination.
{"title":"Racial/Ethnic Bias and Its Role in Severe Maternal Morbidity","authors":"E. Levine, Leah Delfinado, C. Fernandez","doi":"10.33696/gynaecology.4.035","DOIUrl":"https://doi.org/10.33696/gynaecology.4.035","url":null,"abstract":"Racial and ethnic health disparities have been identified by many information sources in recent years, and a specific example of this is severe maternal morbidity and mortality, which includes mortality from postpartum hemorrhage. It is this racial/ethnic health disparity that has been highlighted in news reports that should be of concern to all physicians and healthcare providers, recognizing that women of color have more than three times the risk of dying in childbirth than white women. The details about this are worthy of further examination.","PeriodicalId":93076,"journal":{"name":"Archives of obstetrics and gynaecology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41337030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-12DOI: 10.33696/gynaecology.4.034
Noa Leybovitz-Haleluya, R. Hershkovitz
Introduction: Many gynecologic procedures may benefit from the use of real-time ultrasonography. The goal of this review is to summarize the use of ultrasound in some of the main gynecologic procedures, with focus on cervical cerclage procedure. Recent findings: Ultrasound guidance has been shown to decrease both operative time and complication rates in curettage procedures. In addition, intraoperative ultrasound use reduces recurrence rates after hysteroscopic resection of uterine myoma or septa. Ultrasound guidance may improve the efficiency of cervical cerclage by direct visualization of tightening and assist in measures of prognostic factors following the procedure. Conclusion: Intraoperative ultrasound guidance appears to be a safe and valuable tool for the gynecologic surgeon. It may reduce complication and re-operation rates and may improve the efficacy of some procedures.
{"title":"A Review of the Applications of Intraoperative Ultrasound Guidance in Cervical Cerclage and Selected Gynecological Procedures","authors":"Noa Leybovitz-Haleluya, R. Hershkovitz","doi":"10.33696/gynaecology.4.034","DOIUrl":"https://doi.org/10.33696/gynaecology.4.034","url":null,"abstract":"Introduction: Many gynecologic procedures may benefit from the use of real-time ultrasonography. The goal of this review is to summarize the use of ultrasound in some of the main gynecologic procedures, with focus on cervical cerclage procedure.\u0000\u0000Recent findings: Ultrasound guidance has been shown to decrease both operative time and complication rates in curettage procedures. In addition, intraoperative ultrasound use reduces recurrence rates after hysteroscopic resection of uterine myoma or septa. Ultrasound guidance may improve the efficiency of cervical cerclage by direct visualization of tightening and assist in measures of prognostic factors following the procedure.\u0000\u0000Conclusion: Intraoperative ultrasound guidance appears to be a safe and valuable tool for the gynecologic surgeon. It may reduce complication and re-operation rates and may improve the efficacy of some procedures.","PeriodicalId":93076,"journal":{"name":"Archives of obstetrics and gynaecology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42159311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：