A. Young, L. Sahabi, N. Noma, M. Kalladka, Zhimin Yan
{"title":"Temporomandibular disorders, neuropathic and idiopathic orofacial pain, and headaches: a literature review","authors":"A. Young, L. Sahabi, N. Noma, M. Kalladka, Zhimin Yan","doi":"10.21037/fomm-21-86","DOIUrl":"https://doi.org/10.21037/fomm-21-86","url":null,"abstract":"","PeriodicalId":93098,"journal":{"name":"Frontiers of oral and maxillofacial medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41761856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lijuan Bian, Xi Rui, Zixian Huang, Yan Wang, Zhiquan Huang
{"title":"MiR-29c-3p and MiR-223-3p regulate the proliferation and drug resistance of oral squamous cell carcinoma by targeting ANGPTL4","authors":"Lijuan Bian, Xi Rui, Zixian Huang, Yan Wang, Zhiquan Huang","doi":"10.21037/fomm-21-114","DOIUrl":"https://doi.org/10.21037/fomm-21-114","url":null,"abstract":"","PeriodicalId":93098,"journal":{"name":"Frontiers of oral and maxillofacial medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49471725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Systematic review of platelet-rich fibrin (PRF) centrifugation protocols in oral and maxillofacial surgery and the introduction of AR2T3: an easy to remember acronym to correctly report vertical and horizontal PRF centrifugation","authors":"Carlos Herrera-Vizcaíno","doi":"10.21037/fomm-21-40","DOIUrl":"https://doi.org/10.21037/fomm-21-40","url":null,"abstract":"","PeriodicalId":93098,"journal":{"name":"Frontiers of oral and maxillofacial medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43192897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sitong Ju, Wanlin Fan, A. Rokohl, Yongwei Guo, V. Kakkassery, L. Heindl
{"title":"Genetic factors underlying basal cell carcinoma risk: a narrative review","authors":"Sitong Ju, Wanlin Fan, A. Rokohl, Yongwei Guo, V. Kakkassery, L. Heindl","doi":"10.21037/fomm-21-70","DOIUrl":"https://doi.org/10.21037/fomm-21-70","url":null,"abstract":"","PeriodicalId":93098,"journal":{"name":"Frontiers of oral and maxillofacial medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45212782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anton Brosig, Maximilian Kurz, Roya Piria, Jin Hee Choi, Kristina Erikson, Yongwei Guo, L. Heindl, M. Ranjbar, S. Grisanti, V. Kakkassery
{"title":"Standard of care in treating periocular basal cell carcinoma: a narrative review of the recommendations from the German S2k guidelines","authors":"Anton Brosig, Maximilian Kurz, Roya Piria, Jin Hee Choi, Kristina Erikson, Yongwei Guo, L. Heindl, M. Ranjbar, S. Grisanti, V. Kakkassery","doi":"10.21037/fomm-21-27","DOIUrl":"https://doi.org/10.21037/fomm-21-27","url":null,"abstract":"","PeriodicalId":93098,"journal":{"name":"Frontiers of oral and maxillofacial medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44193400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Temporomandibular joint disorders (TMD) are oro-facial pain conditions that originate from either intraarticular or extraarticular related pathology. Following an accurate diagnosis, there are a variety of non-surgical and surgical management options available. The aim of this article is to review the available pharmacologic agents for the management of extraarticular and intraarticular TMD. These medical options are often first line and are combined with other non-surgical modalities. There are multiple pharmacologic options utilized to treat TMD, from non-steroidal anti-inflammatory drugs (NSAIDs) to muscle relaxants and steroids. Many of these medications are used synergistically to provide symptom improvement and prevention of persistent disease. This paper will discuss the use of the following classes of medications used to manage TMD: NSAIDs, corticosteroids, narcotics, muscle relaxants, anticonvulsants, anxiolytics, and topical therapy. Despite their extensive clinical use, there remains insufficient evidence to recommend one therapy over another. This is due to the lack of systematic reviews and meta-analyses in the current literature. For this reason, there remains a need for a randomized control trial with clear pre-pharmacotherapy diagnoses, blinding, and research objectives. NSAIDs have been recommended as first line therapy for intraarticular disorders with the addition of muscle relaxants if there is a muscle component. Several of the other medications discussed are often patient specific or given secondarily when previous therapy has failed. It is critical to recognize systemic patient factors when prescribing any of these medications to avoid side effects and drug-drug interactions.
{"title":"The use of pharmacologic agents in the management of temporomandibular joint disorder","authors":"Chad Dammling, S. Abramowicz, B. Kinard","doi":"10.21037/FOMM-20-37","DOIUrl":"https://doi.org/10.21037/FOMM-20-37","url":null,"abstract":"Temporomandibular joint disorders (TMD) are oro-facial pain conditions that originate from either intraarticular or extraarticular related pathology. Following an accurate diagnosis, there are a variety of non-surgical and surgical management options available. The aim of this article is to review the available pharmacologic agents for the management of extraarticular and intraarticular TMD. These medical options are often first line and are combined with other non-surgical modalities. There are multiple pharmacologic options utilized to treat TMD, from non-steroidal anti-inflammatory drugs (NSAIDs) to muscle relaxants and steroids. Many of these medications are used synergistically to provide symptom improvement and prevention of persistent disease. This paper will discuss the use of the following classes of medications used to manage TMD: NSAIDs, corticosteroids, narcotics, muscle relaxants, anticonvulsants, anxiolytics, and topical therapy. Despite their extensive clinical use, there remains insufficient evidence to recommend one therapy over another. This is due to the lack of systematic reviews and meta-analyses in the current literature. For this reason, there remains a need for a randomized control trial with clear pre-pharmacotherapy diagnoses, blinding, and research objectives. NSAIDs have been recommended as first line therapy for intraarticular disorders with the addition of muscle relaxants if there is a muscle component. Several of the other medications discussed are often patient specific or given secondarily when previous therapy has failed. It is critical to recognize systemic patient factors when prescribing any of these medications to avoid side effects and drug-drug interactions.","PeriodicalId":93098,"journal":{"name":"Frontiers of oral and maxillofacial medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44198443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: Trigeminal nerve injury is an uncommon complication of outpatient oral surgery and dental procedures such as removal of impacted teeth, placement of endosseous dental implants, and even injection of local anesthesia. In the field of oral and maxillofacial surgery, the two most commonly injured branches of the trigeminal nerve are the inferior alveolar and lingual nerves. Fortunately, most nerve injuries will undergo spontaneous recovery, with only a small percentage of cases resulting in permanent sensory deficits. Background: There is significant morbidity associated with trigeminal nerve injuries, however. Affected patients may complain of difficulty with speech, mastication, and dysesthesia among other symptoms. Once a nerve injury has been identified, the degree of injury is defined based on published classification systems such as the Medical Research Council Scale. Specific neurosensory testing can be performed in the office, and serial neurosensory testing is recorded in order to track a patient’s progress over time. In cases with persistent symptoms, trigeminal nerve microsurgery may be indicated. Surgery entails isolating the affected nerve, removing adherent scar tissue, and occasionally excising a fibrotic portion of the nerve with direct neurorrhaphy. When a large continuity defect is present, a nerve graft may be indicated. Methods: A comprehensive literature review was conducted on the etiology, diagnosis, and treatment of trigeminal nerve injuries. Multiple databases were used to find relevant articles, including PubMed and MEDLINE. Conclusions: Trigeminal nerve injuries occur infrequently in oral and maxillofacial surgery, but such injuries can be worrisome for patients and providers alike. Thankfully, trigeminal nerve microsurgery has the potential to provide affected patients with improved functional sensory recovery and quality of life.
{"title":"Trigeminal nerve injuries in oral and maxillofacial surgery: a literature review","authors":"Matthew Schiavone, V. Ziccardi","doi":"10.21037/fomm-21-26","DOIUrl":"https://doi.org/10.21037/fomm-21-26","url":null,"abstract":"Objective: Trigeminal nerve injury is an uncommon complication of outpatient oral surgery and dental procedures such as removal of impacted teeth, placement of endosseous dental implants, and even injection of local anesthesia. In the field of oral and maxillofacial surgery, the two most commonly injured branches of the trigeminal nerve are the inferior alveolar and lingual nerves. Fortunately, most nerve injuries will undergo spontaneous recovery, with only a small percentage of cases resulting in permanent sensory deficits. Background: There is significant morbidity associated with trigeminal nerve injuries, however. Affected patients may complain of difficulty with speech, mastication, and dysesthesia among other symptoms. Once a nerve injury has been identified, the degree of injury is defined based on published classification systems such as the Medical Research Council Scale. Specific neurosensory testing can be performed in the office, and serial neurosensory testing is recorded in order to track a patient’s progress over time. In cases with persistent symptoms, trigeminal nerve microsurgery may be indicated. Surgery entails isolating the affected nerve, removing adherent scar tissue, and occasionally excising a fibrotic portion of the nerve with direct neurorrhaphy. When a large continuity defect is present, a nerve graft may be indicated. Methods: A comprehensive literature review was conducted on the etiology, diagnosis, and treatment of trigeminal nerve injuries. Multiple databases were used to find relevant articles, including PubMed and MEDLINE. Conclusions: Trigeminal nerve injuries occur infrequently in oral and maxillofacial surgery, but such injuries can be worrisome for patients and providers alike. Thankfully, trigeminal nerve microsurgery has the potential to provide affected patients with improved functional sensory recovery and quality of life.","PeriodicalId":93098,"journal":{"name":"Frontiers of oral and maxillofacial medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44309777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Osseointegration—the biological reality of successful dental implant therapy: a narrative review","authors":"L. Cooper, S. Shirazi","doi":"10.21037/fomm-21-77","DOIUrl":"https://doi.org/10.21037/fomm-21-77","url":null,"abstract":"","PeriodicalId":93098,"journal":{"name":"Frontiers of oral and maxillofacial medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68332258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Peri-implant disease: early diagnosis and non-surgical treatment—a narrative literature review","authors":"TaeHyun Kwon, H. Yen, L. Levin","doi":"10.21037/fomm-21-58","DOIUrl":"https://doi.org/10.21037/fomm-21-58","url":null,"abstract":"","PeriodicalId":93098,"journal":{"name":"Frontiers of oral and maxillofacial medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47244340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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