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Determinants of Stress and Effects on Performance in Part of Lebanese University Medical Residents During Fourth Quarter of 2019 2019年第四季度部分黎巴嫩大学医学院住院医师的压力决定因素及其对表现的影响
Pub Date : 2021-07-19 DOI: 10.47752/sjmh.43.132.148
Zaynab Toufic Zaylaa, Aicha Toufic Zaylaa, R. Dana, B. A. Merhi, Ahmad Adawiye
Background and Objective: Medical residents face challenges that expose them to high risk of developing stress. Stress could reach burnout levels and become harmful to residents and patients. This study aimed to determine the prevalence of stress in current Lebanese University (LU) residents and assessing correlations with some risk factors and consequences. Subjects and Methods: This cross-sectional study involved 130 current LU residents who filled out a questionnaire concerning their demographic data, residency specialty and year, workload, special habits, depression, stress, and frequency of medical errors. Depression and stress scores were obtained using DASS-21 scale. Collected data was analyzed using ANOVA and chi- Square tests in SPSS to find descriptive statistics and correlations. Results: Out of the enrolled residents, 70% had stress ranging between mild and extreme severity. The mean age of the residents was 27.2 years. Females had higher stress than males and gender accounted for 14.1% of variance in stress among residents. Our results implied that internal medicine specialty imposes higher stress than surgery specialty with a significant difference of 4.04 points and working more than 50 hours per week which accounts for 7.6% of variance in stress. Residents had, on average, 4.38 hours of sleep per night and a negative association was found between sleep and stress. Depression was prevalent; 18.5% had severe depression, 3.1% had extremely severe depression, and stress was significantly correlated with it. Similarly, stress was associated with medical errors. No significant correlation was detected between age, marital status, parenting, and residency year, on call duties, or special habits and stress. Conclusion: Stress among medical residents is high due to the different challenges at the personal and occupational level. Stress should be managed especially that it could lead to harmful consequences on the resident’s health and patient’s safety.
背景和目的:住院医师面临的挑战使他们面临发展压力的高风险。压力可能会达到倦怠的程度,并对居民和患者造成伤害。本研究旨在确定目前黎巴嫩大学(LU)居民的压力患病率,并评估与一些风险因素和后果的相关性。受试者和方法:这项横断面研究涉及130名目前居住在LU的居民,他们填写了一份问卷,内容涉及他们的人口统计数据、居住专业和年份、工作量、特殊习惯、抑郁、压力和医疗失误频率。使用DAS-21量表获得抑郁和压力评分。使用SPSS中的方差分析和卡方检验对收集的数据进行分析,以找到描述性统计和相关性。结果:在登记的居民中,70%的人有轻度和极度严重的压力。居民的平均年龄为27.2岁。女性的压力高于男性,性别占居民压力差异的14.1%。我们的研究结果表明,内科专业的压力高于外科专业,差异显著,为4.04分,每周工作时间超过50小时,占压力方差的7.6%。居民平均每晚睡眠4.38小时,睡眠与压力呈负相关。抑郁症普遍存在;18.5%的人患有严重抑郁症,3.1%的人患有极重度抑郁症,压力与之显著相关。同样,压力与医疗失误有关。年龄、婚姻状况、养育子女、居住年份、随叫随到的职责或特殊习惯和压力之间没有显著相关性。结论:由于个人和职业层面的不同挑战,住院医师的压力很大。应控制压力,尤其是压力可能会对住院医生的健康和患者的安全造成有害后果。
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引用次数: 0
COVID-19 in the Indian Territory of Lakshadweep – Role of MMR Vaccination in the Management of COVID-19 Pandemic 印度Lakshadweep地区的新冠肺炎——MMR疫苗接种在新冠肺炎大流行管理中的作用
Pub Date : 2021-07-10 DOI: 10.47752/SJMH.43.123.131
P. Chakravarty
COVID-19 caused by SARS-CoV-2 virus, is a contagious disease which has spread across the entire world within one year and four months of its first appearance in Wuhan, China. Since then new mutated strains of SARS-CoV-2 have been detected in most of the countries including India; the first variant being detected in the United Kingdom (B 7.1.1). We had reported earlier that some regions of Indian Territory had minimal spread of COVID-19 in the population. Among them, one exception was territory of Lakshadweep which did not have even a single case of COVID-19 until December, 2020. However, the first case of COVID-19 emerged in Lakshadweep in January, 2021. The significance of spread of COVID-19 in the population which were previously immunized with MMR (Mumps Measles Rubella) vaccine with plausible role of MMR vaccination in management of COVID-19 has been evaluated in this article.
由SARS-CoV-2病毒引起的新冠肺炎是一种传染性疾病,在中国武汉首次出现后的一年零四个月内已在全世界传播。从那时起,包括印度在内的大多数国家都检测到了新的严重急性呼吸系统综合征冠状病毒2型变异株;在英国检测到的第一种变体(B 7.1.1)。我们早些时候曾报告,印度领土的一些地区新冠肺炎在人群中的传播最小。其中一个例外是Lakshadweep地区,该地区直到2020年12月才出现一例新冠肺炎病例。然而,2021年1月,拉克沙德维普出现了第一例新冠肺炎病例。本文评估了新冠肺炎在先前接种MMR(腮腺炎-麻疹-风疹)疫苗的人群中传播的意义,以及MMR疫苗接种在新冠肺炎管理中的可能作用。
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引用次数: 1
Assessment of Electrolytes, Urea and Creatinine in Patients with Renal Impairment Attending Yobe State Specialist Hospital Damaturu 达马图鲁约贝州立专科医院肾损伤患者电解质、尿素和肌酐的评估
Pub Date : 2021-06-22 DOI: 10.47752/sjmh.42.114.122
Abubakar El-Ishaq, A. M. Garba, Deji Dairo Emanuel
Electrolytes, urea and creatinine are major factor in the determining a healthy kidney performance. Renal impairment is one of the kidney stages that can alter the concentration of these electrolytes. This study was carried out in order to access the biochemical concentrations of urea, electrolytes and creatinine in patients with renal impairment attending Yobe state specialist hospital Damaturu. One hundred (100) blood samples were collected randomly from the patients. Automated chemistry analyzer (Selectra proS) was used for determination of urea and creatinine. For the determination of concentration of electrolytes in blood samples, electrolytes analyzer known as Ion selective electrolyte (ISE) was used. Electrolytes determined and compare with normal values includes: bicarbonate (HCO3-) 20-30 mmol/l, potassium (K+) 2.5-5.0 mmol/l, chloride (Cl-) 95-110 mmol/l, and sodium (Na+) 135-145 mmol/l. The results obtained was distributed into three (3) groups depending on the age categories; group 1 (1-30years), group 2 (31-60 years), and group 3(60-90 years). The gender ratio male to female patients examined was 52:48. Generally, the obtained result showed that females age 31-60 years are the most affected by the renal impairment, and this called for Government intervention in order to solve the causes of kidney impairment in the society.
电解质、尿素和肌酸酐是决定肾脏健康表现的主要因素。肾损伤是肾脏阶段之一,可以改变这些电解质的浓度。本研究旨在了解在达马图鲁约贝州立专科医院就诊的肾损伤患者的尿素、电解质和肌酐的生化浓度。从患者中随机采集一百(100)份血液样本。使用自动化学分析仪(Selectra-proS)测定尿素和肌酸酐。为了测定血液样本中电解质的浓度,使用了被称为离子选择性电解质(ISE)的电解质分析仪。测定并与正常值比较的电解质包括:碳酸氢盐(HCO3-)20-30 mmol/l,钾(K+)2.5-5.0 mmol/l、氯化物(Cl-)95-110 mmol/l和钠(Na+)135-145 mmol/l。所获得的结果根据年龄类别分为三(3)组;第1组(1-30岁)、第2组(31-60岁)和第3组(60-90岁)。检查的男女患者的性别比例为52:48。总体而言,所获得的结果表明,31-60岁的女性受肾损伤的影响最大,这就需要政府干预,以解决社会上肾损伤的原因。
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引用次数: 0
Assessment of Mycological Quality of Groundwater in Yenagoa Metropolis, Bayelsa State, Nigeria 尼日利亚巴耶尔萨州耶纳戈亚大都市地下水真菌质量评估
Pub Date : 2021-04-07 DOI: 10.47752/SJMH.42.73.78
Glory Richard, E. R. Aseibai
This study examined the mycological quality of groundwater in Yenagoa metropolis, Bayelsa State, Nigeria. Triplicate water samples were obtained from 8 locations in the metropolis, and the fungi quality analyzed following standard microbiological procedures. Results showed that total fungi density ranged from 5.2±1.00 x102 to 8.50±0.56 x103 CFU/ml. Analysis of variance indicates statistical variation (p=0.001) across locations with total fungi density exceeding the limit of 102 CFU/ml specified by World Health Organization/Food and Agricultural Organization for potable water in 62.50% of samples. Eight fungi isolates (species) were identified in the study with frequency across the locations as follows: Aspergillus flavus (20.59%), Aspergillus fumigatus (20.59%), Aspergillus niger (20.59%), Cladosporum (5.88%), Fusarium (2.94%), Mucor (8.82%), Penicilium (14.71%) and Rhizopus (5.88%). Of these, Aspergillus species were predominant across the locations. Since groundwater meets diverse purposes, it is essential that it is suitable for the desired use, and this can be done using appropriate technology to make groundwater potable for human consumption.
本研究调查了尼日利亚巴耶尔萨州耶纳戈亚大都市地下水的真菌学质量。从大都市的8个地点采集了三份水样,并按照标准微生物程序对真菌质量进行了分析。结果表明,真菌总密度在5.2±1.00 x102至8.50±0.56 x103 CFU/ml之间。方差分析表明,在62.50%的样本中,真菌总密度超过世界卫生组织/粮食及农业组织规定的102 CFU/ml饮用水限值的地点之间存在统计差异(p=0.001)。本研究共鉴定出8种真菌分离株(种),分布频率如下:黄曲霉(20.59%)、烟曲霉(20.59%)、黑曲霉(20.5 9%)、枝孢菌(5.88%)、镰刀菌(2.94%)、毛霉(8.82%)、青霉(14.71%)和根霉(5.88%)。由于地下水满足不同的用途,因此它必须适合所需的用途,这可以通过使用适当的技术来实现,使地下水可供人类饮用。
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引用次数: 1
An Overview on Biopolymer: A Novelistic Bio-Excipient in Nanoparticulate Drug Delivery 生物聚合物:纳米颗粒给药的新型生物赋形剂综述
Pub Date : 2021-04-07 DOI: 10.47752/SJMH.42.87.92
Sushant Kumar, N. Madhav, A. Verma, K. Pathak, Swarnima Pnadey
The point of this review is to feature the novelistic properties as bioexcipient, isolated from different regular natural sources like legumes, seeds, leaves, vegetables, bits, roots, barks and so on and to investigate the probability in medication conveyance framework. The biomaterial s have been exposed to different physicochemical assessments alongside unearthly examination including UV, FT-IR, Mass and 1H NMR. The confined biomaterial was discovered tom be polymeric in nature having a various utilitarian properties. Based on its inbuilt polymeric properties, the biomaterial secluded from various sources, can be utilized as an option in contrast to accessible standard polymers at extremely efficient economical scale. The separated biopolymer comprised of an interesting polymeric properties like accessible standard polymers. The isolated biomaterial from natural sources shown distinctive inbuilt polymeric properties by execution of various physico-substance examination. As we probably are aware there are various polymers accessible and oftentimes utilized design of novel medication. Yet, detached biomaterial from natural sources have demonstrated about their novelistic various properties like biodegradability, bioretardant, bioadhesive, filmability etc.
本综述的重点是将小说作为生物赋形剂,从不同的常规天然来源,如豆类、种子、叶子、蔬菜、碎片、根、树皮等中分离出来,并探讨其在药物输送框架中的可能性。生物材料已经暴露于不同的物理化学评估以及非常规的检查,包括紫外线,红外光谱,质量和1H核磁共振。封闭生物材料是高分子材料,具有多种实用性能。基于其内置的聚合物特性,这种生物材料可以从各种来源分离出来,与可获得的标准聚合物相比,可以作为一种选择,以极其有效的经济规模加以利用。分离的生物聚合物具有类似于可获得的标准聚合物的有趣的聚合物特性。从天然来源分离的生物材料通过执行各种物理-物质检查显示出独特的内在聚合物特性。正如我们可能意识到的,有各种各样的聚合物可以使用,并且经常用于新型药物的设计。然而,从天然来源分离出来的生物材料已经显示出其独特的各种特性,如生物可降解性、生物阻燃性、生物胶粘性、薄膜性等。
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引用次数: 0
Excess Weight Among Preschool Children in a Lower-Middle-Income Country: Predictors and Perspectives of Prevention 中低收入国家学龄前儿童超重的预测因素和预防展望
Pub Date : 2021-04-07 DOI: 10.47752/SJMH.42.79.86
S. Fredj, Rim Ghammam, N. Zammit, Samah Ben Ammar, A. Ammar, Y. Hasni, S. Chelly, J. Maatoug, Hassen Ghanne
Objective: We aimed to assess the weight status and to determine predicted factors of excess weight among Tunisian preschool children. Methods: We conducted a cross-sectional study among preschoolers attending kindergarten during 2016-2017 school-years in Sousse, Tunisia. The children’s parents completed the self-administered questionnaire. Anthropometric measures (Weight and height) were taken for the children. Weight status considered body mass index (BMI) and excess weight was defined by the International Obesity Task Force (IOTF) standards. Odds ratios for excess weight were calculated using binary logistic regression analyses. Results: A total of 364 preschoolers were included with a mean age 4.49±0.9 years. The ratio boys/girls was 1.05. The prevalence of excess weight was 31.3%; CI95%:[26.7%-36.5%]). Female gender (AOR=1.74; CI95%:[1.07-2.83]), working mother (AOR=1.75;CI95%:[1.04-2.92]), sedentary behavior (AOR=1.87;CI95%:[1.01-3.51]), eating sweets (AOR=1.95;CI95%:[1.19-3.19]), eating while watching television (AOR=2.53;CI95%:[1.23-5.18]) were positively associated with greater risk of excess weight while sleep duration<10h (AOR=0.41;CI95%:[0.24-0.71]) and less educated mother (AOR=0.35;CI95%:[0.12-0.96]) were negatively associated with excess weight. Conclusion: Our results show that the prevalence of overweight and obesity among preschoolers was alarming. Prevention of obesity should start early in life through a multisectoral approach.
目的:我们旨在评估突尼斯学龄前儿童的体重状况,并确定超重的预测因素。方法:我们在突尼斯苏塞2016-2017学年对上幼儿园的学龄前儿童进行了一项横断面研究。孩子的父母完成了自我管理的问卷。对这些儿童进行了人体测量(体重和身高)。国际肥胖特别工作组(IOTF)标准定义了考虑体重指数(BMI)和超重的体重状况。使用二元逻辑回归分析计算超重的比值比。结果:共纳入364名学龄前儿童,平均年龄4.49±0.9岁。男孩/女孩的比例为1.05。超重患病率为31.3%;CI95%:[26.7%-36.5%])。女性(AOR=1.74;CI95%:[1.07-2.83])、工作母亲(AOR=1.75;CI95%2:[1.04-2.92])、久坐行为(AOR=1.87;CI95%1:[1.01-3.51])、吃甜食(AOR=1.95;CI95%3.19]),边看电视边吃(AOR=2.53;CI95%:[12-35.18])与更大的超重风险呈正相关,而睡眠时间<10h(AOR=0.41;CI95%3:[0.24-0.71])和受教育程度较低的母亲(AOR=0.35;CI95%4:[0.12-0.96])与超重呈负相关。结论:我们的研究结果表明,学龄前儿童超重和肥胖的患病率令人担忧。预防肥胖应从生命早期开始,采取多部门方法。
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引用次数: 0
Perspective of Ion Channels in Prostate Cancer 前列腺癌中离子通道的研究进展
Pub Date : 2021-04-06 DOI: 10.47752/SJMH.42.69.72
N. Johnkennedy, B. Hauwa, E. Cletus
Ion channels are membrane proteins, which play a great role in regulating cellular excitability. Alteration of ion channel may contribute to prostate cancer. This could be linked to inherited mutations of ion channel genes which alter channel’s biophysical properties, in a prostate cancer. It is an observed fact that genomic instability is the main cause as well as the major characteristics of prostate cancer. Prostate cancer cell genotypes are mainly characterized by uncontrolled metastasis, resistance to programmed cell death, sustained angiogenesis as well as tissue invasion and metastasis. It is known that genes encoding ion channels are affected in prostate cancer. The Membrane proteins which is involved in signaling in cell and among cells, for coupling of extracellular events with intracellular responses, and for maintaining intracellular ionic homeostasis ion channels which contribute to some extents to pathophysiological features of each prostate cancer.
离子通道是一种膜蛋白,在调节细胞兴奋性方面起着重要作用。离子通道的改变可能与前列腺癌的发生有关。这可能与前列腺癌中离子通道基因的遗传突变有关,这种突变改变了离子通道的生物物理特性。这是一个观察到的事实,基因组的不稳定性是前列腺癌的主要原因和主要特征。前列腺癌细胞基因型的主要特征是不受控制的转移、抵抗程序性细胞死亡、持续的血管生成以及组织侵袭和转移。众所周知,编码离子通道的基因在前列腺癌中受到影响。膜蛋白参与细胞内和细胞间的信号传递,参与细胞外事件与细胞内反应的耦合,参与维持细胞内离子稳态的离子通道,在一定程度上参与各种前列腺癌的病理生理特征。
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引用次数: 0
Assessment of Hazards, Health Consciousness and Health Seeking Behavior of Automobile Mechanics in Cape Coast Metropolis, Ghana 加纳开普海岸大都市汽车机械师的危险性、健康意识和健康寻求行为评估
Pub Date : 2021-04-04 DOI: 10.47752/SJMH.42.60.68
S. Mensah, M. A. Essuman, Augustine Brah, Phyllis A. Aboagye, A. Boye
Objective: Automobile mechanics are exposed to a wide range of chemicals contained in brake fluids, detergents, lubricants, paints, metal cleaners, solvents and fluids. Constant exposure to these chemicals puts mechanics at risk. This study aimed to assess the diverse hazards in working environment of automobile mechanics in Cape Coast Metropolis, Ghana. Method: A questionnaire-based survey was conducted among 225 automobile mechanics in Cape Coast Metropolis. The questionnaire sought information on possible hazards, health problems associated with work, use of personal protective equipment and where workers seek help when they fall ill. The interview was followed by measurement of blood pressure, hematological profile and liver function test. Results: Most auto-mechanics, welders, car sprayers and electricians were exposed to diesel, electrodes, paints and soldering iron respectively. Productive cough, abdominal pain, nausea and breathlessness were common clinical conditions reported by these mechanics. Blood pressure and haematological parameters were all in their normal ranges when compared to bench reference ranges. Conclusion: Most mechanics were conscious about their health, however, showed poor health seeking behavior and poor use of protective measures against possible hazards. Proper education of this economically viable group on workplace hazards, the types and properties of the different protective devices in order to safeguard their health is needed.
目的:汽车机械师会接触到刹车液、清洁剂、润滑剂、油漆、金属清洁剂、溶剂和液体中含有的各种化学物质。经常接触这些化学物质会使机械师处于危险之中。本研究旨在评估迦纳海岸角都市汽车机械师工作环境的各种危害。方法:采用问卷调查的方式对海岸角市区225名汽车修理工进行调查。调查问卷寻求关于可能的危害、与工作有关的健康问题、个人防护设备的使用情况以及工人生病时在何处寻求帮助的信息。访谈后进行血压测量、血液学检查和肝功能检查。结果:大多数汽车修理工、焊工、汽车喷雾器和电工分别接触柴油、电极、油漆和烙铁。生产性咳嗽、腹痛、恶心和呼吸困难是这些机械师报告的常见临床症状。血压和血液学参数均在正常范围内。结论:绝大多数机械师的健康意识较强,但其健康寻求行为较差,对可能发生的危险采取的防护措施较少。需要对这一经济上可行的群体进行适当的教育,使他们了解工作场所的危险、不同防护装置的类型和特性,以保障他们的健康。
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引用次数: 0
Socio-Demographic Association of Multiple Risk Factors and Their Clustering in Urban Population of Adults 城市成年人口中多种危险因素的社会人口学关联及其聚类
Pub Date : 2021-04-01 DOI: 10.47752/SJMH.42.52.69
D. Chebil, J. Maatoug, R. Ghammem, N. Zammit, S. Fredj, H. Ghannem
Introduction: The purpose of this study was to estimate the prevalence and identify factors associated with simultaneous risk factors occurrence (clustering) for chronic diseases among adults. Methods: A cross-sectional population-based study was carried out with 1977 adults in Sousse, Tunisia. The simultaneous occurrence of tobacco smoking, physical inactivity, inadequate or unhealthy diet, obesity, and high blood pressure was assessed. The independent variables were demographic and socioeconomic characteristics. Results: Overall, 61% of Tunisian adults had two or more unhealthy risk factors compared to only 11% with none of the five risk factors. Prevalence of risk factors was greater in older subjects, females, married, with lower education, unemployed, and those with high socioeconomic status. Risk factors clustered in multiple combinations. The simultaneous presence of all risk factors was 40% higher of what would be expected by combining the individual prevalence of these risk factors. Physical inactivity, unhealthy diet, obesity, and high blood pressure showed the strongest association among the clusters. Conclusion: Multiple chronic disease risk factors are frequent and occur more often than expected among Tunisian adults, especially women, married, older subjects, with low education and high socioeconomic level. Information on high risk groups will help in planning future preventive strategies.
引言:本研究的目的是估计成人慢性病的患病率,并确定与同时发生(聚集)危险因素相关的因素。方法:对突尼斯苏塞市1977名成年人进行了一项基于人群的横断面研究。评估了吸烟、不运动、饮食不足或不健康、肥胖和高血压同时发生的情况。自变量是人口统计学和社会经济特征。结果:总体而言,61%的突尼斯成年人有两种或两种以上的不健康风险因素,而只有11%的人没有这五种风险因素。风险因素在年龄较大的受试者、女性、已婚、受教育程度较低、失业和社会经济地位较高的人群中的患病率较高。风险因素聚集在多个组合中。所有风险因素的同时存在比结合这些风险因素的个体流行率预期的高40%。不运动、不健康饮食、肥胖和高血压在这些群体中表现出最强的相关性。结论:突尼斯成年人,尤其是女性、已婚、年龄较大、受教育程度较低、社会经济水平较高的人群,存在多种慢性病风险因素,且发生率高于预期。关于高风险群体的信息将有助于规划未来的预防战略。
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引用次数: 0
Analysis of Cuorum Sensing-Dependent Virulence Factors and Drug Resistance in Pseudomonas Aeruginosa Strains 铜绿假单胞菌粪感依赖毒力因子及耐药性分析
Pub Date : 2021-03-26 DOI: 10.47752/SJMH.41.46.51
J. J. Alba-Romero, P. Ruíz-Flores, G. Castro-Escarpulli, S. Hernández-González, A. Martínez-Romero, J. L. Ortega-Sánchez
The objective was to analyze the virulence factors dependent on Cuorum Sensing and drug resistance in strains of Pseudomonas aeruginosa. Virulence factors such as pyocyanin, beta-lactamase, biofilm, and antibiotic resistance were determined in 95 strains of P. aeruginosa isolated from hospitalized patients. Genus and species were identified by protein analysis by MALDI-TOF. 100% of the strains were resistant to at least one drug and the highest proportion was 32 strains resistant to 4 drugs and 5 resistant PAM strains. In the analysis of virulence factors, 98.8% produce at least one virulence factor and 48.9% are beta-lactamase producers. Therefore, it is concluded that P. aeruginosa strains isolated from clinical samples constitute a risk factor for hospitalized patients.
目的分析铜绿假单胞菌的Cuorum敏感毒力因子和耐药性。对从住院患者中分离的95株铜绿假单胞菌进行了毒力因子测定,如绿脓杆菌素、β-内酰胺酶、生物膜和抗生素耐药性。通过MALDI-TOF蛋白质分析鉴定了属和种。100%的菌株对至少一种药物具有耐药性,最高比例为32株对4种药物具有抗性,5株对PAM具有抗性。在毒力因子分析中,98.8%产生至少一种毒力因子,48.9%产生β-内酰胺酶。因此,可以得出结论,从临床样本中分离出的铜绿假单胞菌菌株构成了住院患者的风险因素。
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引用次数: 0
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Sumerianz journal of medical and healthcare
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