Microbial resistance through extended-spectrum β-lactamase (ESBL) has emerged globally, and ESBL –producing Enterobacteriacae are recognized worldwide as nosocomial pathogens of major importance. Several phenotypic tests have been recommended for screening and confirmation of ESBL-producing organisms, but these are usually performed on isolated organisms following culture and antibiotic susceptibility testing.
{"title":"Methods of ESBLs Detection in Clinical Microbiology Lab","authors":"A. Abdelmoktader","doi":"10.23880/vij-16000222","DOIUrl":"https://doi.org/10.23880/vij-16000222","url":null,"abstract":"Microbial resistance through extended-spectrum β-lactamase (ESBL) has emerged globally, and ESBL –producing Enterobacteriacae are recognized worldwide as nosocomial pathogens of major importance. Several phenotypic tests have been recommended for screening and confirmation of ESBL-producing organisms, but these are usually performed on isolated organisms following culture and antibiotic susceptibility testing.","PeriodicalId":93395,"journal":{"name":"Virology & immunology journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68921160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hepatitis C virus is a causative agent of both acute and chronic liver disease and is associated with varied clinical presentations. Aims & Objectives: The study was undertaken co-relate the various clinical manifestations and derangement of liver and endocrine function with HCV viral replication and to find out the impact of Sofosbuvir combination therapy. Result: Derangement of liver function as indicated by Bilirubin, AST and ALT has significant corelation with active viral replication as indicated by viral load assay. Derangement of Thyroid function is also found in a third of HCV infected patients. The study also found Sofosbuvir combination therapy induces an early virologic response in both Genotype 1 and Genotype 3 infection.
{"title":"Study of Co-Relation between Hepatitis C Viral Load with Clinical Presentations, Laboratory Investigations and Sofosbuvir Combination Therapy","authors":"Gautam B","doi":"10.23880/vij-16000223","DOIUrl":"https://doi.org/10.23880/vij-16000223","url":null,"abstract":"Hepatitis C virus is a causative agent of both acute and chronic liver disease and is associated with varied clinical presentations. Aims & Objectives: The study was undertaken co-relate the various clinical manifestations and derangement of liver and endocrine function with HCV viral replication and to find out the impact of Sofosbuvir combination therapy. Result: Derangement of liver function as indicated by Bilirubin, AST and ALT has significant corelation with active viral replication as indicated by viral load assay. Derangement of Thyroid function is also found in a third of HCV infected patients. The study also found Sofosbuvir combination therapy induces an early virologic response in both Genotype 1 and Genotype 3 infection.","PeriodicalId":93395,"journal":{"name":"Virology & immunology journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68921192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lassa Fever: Current Treatment and Prospects of an Effective Vaccine","authors":"Chikere A. Anusiem","doi":"10.23880/vij-16000207","DOIUrl":"https://doi.org/10.23880/vij-16000207","url":null,"abstract":"","PeriodicalId":93395,"journal":{"name":"Virology & immunology journal","volume":"110 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68920756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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