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Attitudes of Lazarski University Medical Students towards Disaster Medicine; Questionnaire Survey 拉扎尔斯基大学医学生对灾难医学的态度问卷调查
Pub Date : 2023-01-25 DOI: 10.26420/austinjpublichealthepidemiol.2023.1141
M. M., M. A., Piotrowska K, Złotorzyńska K, Jabłońsk L, O. P., Gołębiak I
Background: The paper presents issues related to the deficit in medical student training in the field of disaster medicine. According to Polish medical educational standards, there is no obligation imposed by the legislator to educate future doctors in disaster medicine. However, there is the university’s authorial capacity, which, as exemplified by Lazarski University in Warsaw, has been successfully implemented for teaching students disaster medicine and has demonstrated effectiveness in education in this field. Methods: The study was conducted by means of a diagnostic survey method, using an authorial survey questionnaire. A total of 168 medical students between 2020 and 2022 took part in the survey. The questionnaire contained 10 questions, one- and multiple-choice ones, of which one was about self-assessment. Students completed the questionnaire twice, before and after the disaster medicine course. Conclusion: The results clearly indicate the need for educational standards for issues related to disaster medicine, especially for faculties of medicine, where future doctors will be trained to deal with large numbers of casualties. Students manifest the need for such courses during their studies and as part of postgraduate training.
背景:本文介绍了灾害医学领域医学生培训不足的相关问题。根据波兰医学教育标准,立法者没有规定对未来的医生进行灾难医学教育的义务。然而,也有大学的著述能力,华沙的拉扎尔斯基大学就是一个例子,这种能力已经成功地用于教授学生灾害医学,并在这一领域的教育中显示出效力。方法:本研究采用诊断性调查方法,采用作者调查问卷。在2020年至2022年期间,共有168名医学生参与了这项调查。问卷共10个问题,单选题和多项选择题,其中一个是关于自我评价的。学生在灾难医学课程前后分别完成了两次问卷调查。结论:研究结果清楚地表明,需要制定灾害医学相关问题的教育标准,特别是针对医学院系,未来的医生将接受培训,以应对大量的伤亡。学生们在学习期间以及作为研究生培训的一部分,对这些课程都有需求。
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引用次数: 0
Paricalcitol Ameliorated Dextran-Sulfate-Sodium-Induced Colitis in Mice through MKP-1/P38 MAPK Signaling Pathway Paricalcitol通过MKP-1/P38 MAPK信号通路改善右旋糖酐-硫酸钠诱导的小鼠结肠炎
Pub Date : 2023-01-16 DOI: 10.26420/austinjpublichealthepidemiol.2023.1139
Liyuan Lv, Guinan Liv, Man Yang, Tao Chen, Xiang Li, Jun Zhang, Jie Liu, Yi Liu
Background and Aim: Ulcerative Colitis (UC), a type of inflammatory bowel disease, of which the accurate pathogenesis is not yet well understand. Recently, the Vitamin D/VDR signaling pathway and the activated vitamin D analogues have been proved as playing important role in the pathogenesis of UC. In the present study, our objective was to evaluate the effect of Vitamin D analogues paricalcitol on dextran-sulfate-sodium-induced colitis in a mouse model. Methods: We evaluated the effects of the activated vitamin D analogues paricalcitol on the development of Dextran-Sulfate-Sodium-(DSS)-induced colitis. Clinical symptoms were evaluated by the Disease Activity Index (DAI) and tissue samples were evaluated by Histopathological Scoring (HS). Meanwhile, the mucosal mRNA expression of cytokines, Tumor Necrosis Factoralpha (TNF-a), Interleukin-6 (IL-6), Interleukin-10 (IL-10), Interleukin-17 (IL-17) were analyzed by real-time semi quantitative reverse transcription polymerase chain reaction. The mucosal protein VDR, p38 Mitogen-Activated Protein Kinase (P38-MAPK) and Mitogen-Activated Protein Kinase Phosphatase-1 (MKP-1) expressions of the vitamin D/VDR signaling pathway were analyzed using Western blot. Results: The results showed that the weight loss and colon length shortening of DSS-induced mice were significantly improved after paricalcitol treatment. In addition, both DAI and HS were significantly reduced. Paricalcitol down regulated the mucosal expression of messenger RNA of pro-inflammatory cytokines TNF-a, IL-6 and IL-10 and upregulated anti-inflammatory cytokines IL-17. Both VDR protein expression and MKP-1 level increased, whereas the mucosal expression of p38-MAPK was found to be decreased. Conclusion: Activated Vitamin D analogues paricalcitol can ameliorate the development of DSS-induced colitis through the Vitamin D/VDR signaling pathway.
背景与目的:溃疡性结肠炎(UC)是一种炎症性肠病,其确切的发病机制尚不清楚。近年来,维生素D/VDR信号通路和活化的维生素D类似物被证实在UC的发病机制中起重要作用。在本研究中,我们的目的是在小鼠模型中评估维生素D类似物特别糖醇对葡聚糖-硫酸钠诱导的结肠炎的影响。方法:我们评估了活性维生素D类似物特化糖醇对葡聚糖-硫酸钠(DSS)诱导结肠炎的影响。采用疾病活动指数(DAI)评价临床症状,采用组织病理学评分(HS)评价组织标本。同时,采用实时半定量反转录聚合酶链式反应分析细胞因子、肿瘤坏死因子- α (TNF-a)、白细胞介素-6 (IL-6)、白细胞介素-10 (IL-10)、白细胞介素-17 (IL-17) mRNA的表达。Western blot检测维生素D/VDR信号通路粘膜蛋白VDR、p38丝裂原活化蛋白激酶(p38 - mapk)和丝裂原活化蛋白激酶磷酸酶-1 (MKP-1)的表达。结果:经特化枸橼醇处理后,dss诱导小鼠的体重减轻和结肠长度缩短均有明显改善。此外,DAI和HS均明显降低。Paricalcitol下调促炎细胞因子TNF-a、IL-6、IL-10 mrna的表达,上调抗炎细胞因子IL-17的表达。VDR蛋白表达和MKP-1水平均升高,而粘膜p38-MAPK表达降低。结论:活化的维生素D类似物特别糖醇可通过维生素D/VDR信号通路改善dss诱导的结肠炎的发展。
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引用次数: 0
Tuberculosis in Regional Australia: Ectopic Pregnancy Complicating Indolent Genital Tract Disease 澳大利亚地区的结核病:异位妊娠合并生殖道疾病
Pub Date : 2023-01-16 DOI: 10.26420/austinjpublichealthepidemiol.2023.1140
X. B, Brown C, A. A, McCully B
Female genital Tuberculosis (TB) is uncommon in Australia. It may, however, be a rarely considered cause of infertility and early pregnancy failure. We report the case of a 19-year-old migrant woman living in regional Australia who presented with ectopic pregnancy following prior treatment for genital tuberculosis. We highlight the vulnerability of migrant and indigenous Australians to chronic disease, the barriers that affect successful treatment and the strategies needed to mitigate disparity of healthcare providers not otherwise encountered in metropolitan populations.
女性生殖器结核在澳大利亚并不常见。然而,它可能是一个很少被考虑的不孕不育和早孕失败的原因。我们报告了一名居住在澳大利亚地区的19岁移民妇女的病例,她在接受生殖器结核治疗后出现异位妊娠。我们强调了澳大利亚移民和土著人对慢性病的脆弱性,影响成功治疗的障碍,以及缓解大都市人口中未遇到的医疗保健提供者差异所需的战略。
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引用次数: 0
Correlation between Count Score and Cardiovascular Events in Maintenance Hemodialysis Patients 维持性血液透析患者计数评分与心血管事件的相关性
Pub Date : 2023-01-10 DOI: 10.26420/austinjpublichealthepidemiol.2023.1138
L. L, Y. Y, Luo T, F. M., Z. Y., Tian Lq, Wu Q, L. J., Liu F, Liu W, Yang L, X. J, Y. Y
Purpose: Evaluating the nutritional status of patients with Maintenance Hemodialysis (MHD) based on CONUT score to explore its relationship with Cardiovascular Disease (CVD) in MHD patients. Methods: Baseline data of new-coming MHD patients hospital hemodialysis center of our hospital undergoing hemodialysis treatment for the first time from January 1, 2014 to June 30, 2020 was collected. Cardiovascular events were used as the end point. Patients were divided into three groups according to CONUT score: normal nutrition group (CONUT score 0-1), mild malnutrition group (CONUT score 2-4) and moderate to severe malnutrition group (CONUT score ≥5), and the differences of clinical data and prognosis among the three groups were compared. The risk factors of cardiovascular events in MHD patients were determined by Logistic regression analysis, and the predictive ability of the risk factors was observed with Receiver Operating Characteristic (ROC) curve. Results: A total of 424 MHD patients were included. According to the CONUT score, 31 (7.3%) patients were in the normal nutrition group, 160 (37.7%) patients in the mild malnutrition group, and 233 (55.0%) patients in the moderate to severe malnutrition group. A total of 159 patients had cardiovascular events, including 3 cases (9.7%) in the normal nutrition group, 38 cases (23.8%) in the mild malnutrition group, and 118 cases (50.6%) in the moderate to severe malnutrition group. The worse the nutritional status of patients is, the higher the incidence rate of cardiovascular events is (P<0.05). Logistic regression analysis showed that CONUT score and age were independently correlated with cardiovascular events in MHD patients (P<0.05). ROC curve analysis showed that CONUT score and age predicted cardiovascular events in MHD patients with areas under the curve were 0.683 (95% CI: 0.632-0.735, P<0.001) and 0.702 (95% CI: 0.702), respectively. 0.652 -- 0.753, P<0.001), the optimal cut-off points were 4.5 (≥5 in combination) and 68.5, the sensitivity were 74.2% and 49.1%, and the specificity was 56.6% and 81.1%, respectively. Conclusion: There is a certain correlation between CONUT score the happening of cardiovascular events and MHD patients.
目的:基于CONUT评分评估维持性血液透析(MHD)患者的营养状况,探讨其与MHD患者心血管疾病(CVD)的关系。方法:收集2014年1月1日至2020年6月30日我院血液透析中心首次接受血液透析治疗的新来MHD患者的基线数据。心血管事件被用作终点。根据CONUT评分将患者分为三组:营养正常组(CONUT评分0-1)、轻度营养不良组(CONUT评分2-4)和中度至重度营养不良组,CONUT评分≥5,比较三组患者的临床数据和预后差异。采用Logistic回归分析确定MHD患者心血管事件的危险因素,并用受试者操作特征(ROC)曲线观察危险因素的预测能力。结果:共纳入424名MHD患者。根据CONUT评分,31名(7.3%)患者属于正常营养组,160名(37.7%)患者属于轻度营养不良组,233名(55.0%)患者属于中度至重度营养不良组。共有159名患者发生心血管事件,其中正常营养组3例(9.7%),轻度营养不良组38例(23.8%),中度至重度营养不良组118例(50.6%)。患者的营养状况越差,心血管事件的发生率越高(P<0.05)。Logistic回归分析显示,CONUT评分和年龄与MHD患者的心血管事件独立相关(P<0.05),ROC曲线分析显示,曲线下区域的MHD患者CONUT评分与年龄预测的心血管事件分别为0.683(95%CI:0.632-0.735,P<0.001)和0.702(95%可信区间:0.702)。0.652-0.753,P<0.001),最佳分界点为4.5(联合≥5)和68.5,敏感性分别为74.2%和49.1%,特异性分别为56.6%和81.1%。结论:CONUT评分与MHD患者心血管事件的发生有一定的相关性。
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引用次数: 0
Optimalresistive Force Selection and Upper Body Contribution in the Assessment of Power during High Intensity Cycle Ergometry: An Unresolved Issue 最佳阻力选择和上半身贡献在高强度循环几何中的力量评估:一个未解决的问题
Pub Date : 2023-01-02 DOI: 10.26420/austinjpublichealthepidemiol.2023.1137
Baker Js, T. D
The purpose of this study is to outline and comment on the issue of optimal resistive force selection and the upper body contribution during high intensity performance using cycle ergometers. The paper provides an historical perspective of the experimental research in developing optimal resistive forces, and the upper body contribution to the test. To date, these issues are still unresolved and further work is needed to provide valid and reliable optimal resistive forces, and to consider the upper body contribution during anaerobic performance assessment of specific subject populations. Studies are needed to identify the optimal resistive force and velocity for subjects who span a wide range of body masses and abilities. These studies should include athletes of various specialties and proficiency. Further to this, the studies should also explore individuals with disabilities and muscular and neurovascular disorders such as, obesity, muscular sclerosis and muscular dystrophy.
本研究的目的是概述和评论使用自行车测力计在高强度性能过程中最佳阻力选择和上身贡献的问题。本文提供了开发最佳阻力的实验研究的历史视角,以及上身对测试的贡献。到目前为止,这些问题仍未解决,需要进一步的工作来提供有效和可靠的最佳阻力,并在特定受试者群体的厌氧性能评估过程中考虑上半身的贡献。需要进行研究,以确定跨各种身体质量和能力的受试者的最佳阻力和速度。这些研究应包括不同专业和水平的运动员。除此之外,研究还应探索残疾人以及肌肉和神经血管疾病,如肥胖、肌肉硬化症和肌营养不良。
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引用次数: 0
Disaster Preparedness among Nepalese Residing in Japan: a Mini-Review 居住在日本的尼泊尔人的防灾能力:一个小回顾
Pub Date : 2022-12-06 DOI: 10.26420/austinjpublichealthepidemiol.2022.1136
Bhandari Akc, Takahashi O
The rate of natural disasters has shown prolific increment in last few years with Asia being one of the regions with highest occurrence of disasters like earthquakes, tsunamis, floods, landslides and so on. Nepalese immigrants are highly increasing in Japan hence the objective of this study was to identify the Knowledge, Attitude and Practice (KAP) of disaster preparedness among them. A structured questionnaire was used and bivariable and multivariable logistic regression analysis was performed to identify the determinants of knowledge, attitude and practice. Total of 404 Nepalese participated in this study and we identified that Nepalese immigrants has lower practice of natural disaster preparedness. We also identified that Japanese language is the biggest barrier for Nepalese to seek correct information on disaster preparedness. Thus, Japan government in light of growing immigrant population should think about policies to include information related to natural disasters in Nepali language into their official websites in order to increase their KAP on disaster preparedness.
近几年来,自然灾害的发生率呈大幅上升趋势,亚洲是地震、海啸、洪水、山体滑坡等灾害发生率最高的地区之一。尼泊尔移民在日本的人数正在急剧增加,因此本研究的目的是确定其中的备灾知识、态度和实践(KAP)。使用结构化问卷,进行双变量和多变量逻辑回归分析,以确定知识、态度和实践的决定因素。共有404名尼泊尔人参与了这项研究,我们发现尼泊尔移民的自然灾害防备水平较低。我们还指出,日语是尼泊尔人寻求正确备灾信息的最大障碍。因此,鉴于移民人口的不断增长,日本政府应该考虑制定政策,将尼泊尔语的自然灾害相关信息纳入其官方网站,以提高其防灾KAP。
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引用次数: 0
Pregnancy-Induced Proinflammatory Immunological Tone and Gut Microbiota Profile are not Reversed at the Delivery 妊娠诱导的促炎性免疫色调和肠道微生物群特征在分娩时没有逆转
Pub Date : 2022-11-09 DOI: 10.26420/austinjpublichealthepidemiol.2022.1135
Hermansson H, Rautava S, Löyttyniemi E, Salminen S, Isolauri E
Pregnancy is associated with an increased production of pro-inflammatory factors and concomitant modifications in the gut microbiota composition. The persistence of these pregnancy-associated immunologic and gut microbiota profiles was assessed in 43 women. In the postpartum period the gut microbiota composition remained relatively unchanged while the concentrations of the proinflammatory cytokines continued to increase.
妊娠与促炎因子的产生增加以及肠道菌群组成的改变有关。在43名妇女中评估了这些与妊娠相关的免疫和肠道微生物群概况的持久性。在产后期间,肠道菌群组成保持相对不变,而促炎细胞因子的浓度继续增加。
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引用次数: 0
Pros and Cons of Infectious Outbreak and Pandemic Driven Ruralisation 传染病爆发和流行病驱动的全球化的利弊
Pub Date : 2022-11-04 DOI: 10.26420/austinjpublichealthepidemiol.2022.1134
Phukon Jc, Sastry Gn
Infectious diseases played a major role and have influenced modern society, culture, and farming practices. The threat posed by emerging zoo noses to the world’s economy, health and safety is tremendous and the way Covid-19 pandemic have disrupted the civilisation is a complete failure and exposes the vulnerabilities of twenty first century. The frequency of Emerging Infectious Diseases (EIDs) and there is increased burden of economic loss. The emergence of these diseases is frequently caused by interactions between human, wild animals, and domestic animals as well as by rapidly changing environmental conditions. As pandemic redefines the living style there is different patterns of adaptation of the human beings. This article examines the driving forces responsible for emerging infectious pandemic and its impact on lives and livelihood of people. The preventive measures to tackle with EIDs are explained and how new norms are to be adopted for better co habiting with other species.
传染病发挥了重要作用,影响了现代社会、文化和农业实践。新出现的“动物园鼻”对世界经济、健康和安全构成了巨大威胁,新冠疫情破坏人类文明的方式是彻底失败的,暴露了21世纪的脆弱性。新发传染病(eid)的发生频率和经济损失负担的增加。这些疾病的出现往往是由人类、野生动物和家畜之间的相互作用以及迅速变化的环境条件引起的。随着大流行对生活方式的重新定义,人类有不同的适应模式。本文探讨了新出现的传染病大流行的驱动力及其对人们生活和生计的影响。介绍了应对eid的预防措施,以及如何采用新的规范以更好地与其他物种共存。
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引用次数: 1
Demographic and Occupational Factors Affecting Fatigue and Social Support among Nurses in the Emergency Department: A Cross-Sectional Study 影响急诊科护士疲劳和社会支持的人口统计学和职业因素:一项横断面研究
Pub Date : 2022-10-26 DOI: 10.26420/austinjpublichealthepidemiol.2022.1132
Theofilou P, Tzavella F, Zyga S
The aim of the present study is the investigation of the levels of fatigue and social support in nursing staff working in the Emergency Department of General Hospitals in the broader area of Athens. Moreover, the impact of demographic and occupational factors on fatigue and social support was examined. This is a quantitative cross-sectional study including 62 nurses who completed the Fatigue Assessment Scale (FAS) and the Multidimensional Scale of Perceived Social Support (MSPSS). Based on the results, males presented higher score of mental fatigue compared to females (p=0,015) while nurses with master or PhD degree appeared to have more support from their family in comparison to those with lower educational level (p=0,040). Further, the results demonstrated a statistically significant and negative correlation between working hours per week and the perceived social support from friends (r= -0,302, p=0,021) as well as the total social support (r= -0,296, p=0,024). The findings show that there is a strong effect of demographic and occupational factors on fatigue and social support among nurses.
本研究的目的是调查雅典广大地区综合医院急诊科护理人员的疲劳和社会支持水平。此外,还研究了人口和职业因素对疲劳和社会支持的影响。这是一项定量的横断面研究,包括62名护士,他们完成了疲劳评估量表(FAS)和感知社会支持多维量表(MSPSS)。根据研究结果,与女性相比,男性的精神疲劳得分更高(p=0.015),而与教育水平较低的护士相比,拥有硕士或博士学位的护士似乎得到了更多的家庭支持(p=0.040)。此外,研究结果表明,每周工作时间与来自朋友的感知社会支持(r=-0302,p=0.021)以及总社会支持(r=-0296,p=0.024)之间存在统计学上显著的负相关。研究结果表明,人口统计学和职业因素对护士的疲劳和社会支持有很大影响。
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引用次数: 0
Multilevel Barriers to Access Health and HIV Care Among African, Caribbean, and Black Men and Youths in Ottawa, Ontario: A Qualitative Study 安大略省渥太华的非洲、加勒比和黑人男子和青年获得保健和艾滋病毒护理的多层次障碍:一项定性研究
Pub Date : 2022-10-17 DOI: 10.26420/austinjpublichealthepidemiol.2022.1131
Gebremeskel At, Kakuru Dm, Etowa Jb
Background: Ontario is home to the largest proportion of African, Caribbean, and Black (ACB) people living in Canada. This group isdisproportionately affected by the HIV pandemic. However, there is limited evidence on how multilevel barriersintersect and mutually reinforce each other to restrict access to health and HIV care. This paper examines multilevel barriers to access health and HIV carebased on the lived experiences of ACB people in Ottawa and Ontario. Method: We conducted community based qualitative study with selfidentified ACB men aged 16 and over, living in Ottawa. Our approach is informed by intersectionality theory and Socio-Ecological Model (SEM). A purposive sampling technique was used to recruit participants. We conducted six Focus Group Discussions and 16 In-depth Interviews. Sixty-three people participated in this study. N Vivo software was used for data management and thematic analysis. Results: Six major themes were identified including barriers to access health and HIV care among heterosexual ACB men in Ottawa and Ontario, which is the focus of this paper. This theme is discussed through three subthemes:( 1)individual level low economic, knowledge,and racial identity;(2) community-level lack of culturally responsive services, few community leaders and lack of neighbourhood resources;and (3) system-level embedded discriminatory policies and practices, anti-Black racism, and traumasand legacies of colonialism. Conclusion: Addressing health inequality and enhancing the accessibility and provision of healthcare for ACB populations in Ontario is critical for their health and well-being. An inter sectionality lens and SEM should be given priority to guide understanding of the causes of inequities and the complex ways multilevel barriers to access healthcare relates, intersects, and mutually reinforces one another. Multiple level strategies with strong emphasis at a systemic level, and culturally appropriate approaches are crucial to address barriers while enhancing collaboration among multilevel stakeholders including heterosexual ACB men’s and ACB organizations.
背景:安大略省是居住在加拿大的非洲、加勒比和黑人(ACB)人口比例最大的地方。这一群体受到艾滋病毒流行病的影响尤为严重。然而,关于多层障碍如何相互影响和相互加强以限制获得保健和艾滋病毒护理的证据有限。本文根据渥太华和安大略省ACB人群的生活经历,探讨了获得保健和艾滋病毒护理的多层次障碍。方法:我们对居住在渥太华的16岁及以上的ACB男性进行了基于社区的定性研究。我们的方法是由交叉理论和社会生态模型(SEM)通知。采用有目的的抽样技术来招募参与者。我们进行了6次焦点小组讨论和16次深度访谈。63人参加了这项研究。采用N Vivo软件进行数据管理和专题分析。结果:确定了六个主要主题,包括渥太华和安大略省异性恋ACB男性获得保健和艾滋病毒护理的障碍,这是本文的重点。这一主题通过三个子主题进行讨论:(1)个人层面的低经济、知识和种族认同;(2)社区层面缺乏文化响应服务,社区领导人很少,缺乏邻里资源;(3)系统层面嵌入的歧视性政策和做法,反黑人种族主义,以及殖民主义的创伤和遗产。结论:解决保健不平等问题,加强安大略省ACB人口获得和提供保健服务的机会,对他们的健康和福祉至关重要。应优先考虑交叉性镜头和SEM,以指导对不平等原因的理解,以及获得医疗保健的多层次障碍相互关联、交叉和相互加强的复杂方式。强调系统层面的多层次战略,以及文化上适当的方法,对于解决障碍,同时加强包括异性恋ACB男性和ACB组织在内的多层次利益相关者之间的合作至关重要。
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引用次数: 0
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Austin journal of public health and epidemiology
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