Pub Date : 2023-02-25Epub Date: 2023-02-15DOI: 10.53388/idr2023004
Charlotte Blanche Oguejiofor, Kenechi Miracle Ebubechukwu, George Uchenna Eleje, Emmanuel Onyebuchi Ugwu, Joseph Tochukwu Enebe, Kingsley Emeka Ekwuazi, Chukwuemeka Chukwubuikem Okoro, Boniface Chukwuneme Okpala, Charles Chukwunomunso Okafor, Nnanyelugo Chima Ezeora, Emeka Ifeanyi Iloghalu, Chidebe Christian Anikwe, Chigozie Geoffrey Okafor, Polycarp Uchenna Agu, Emeka Philip Igbodike, Iffiyeosuo Dennis Ake, Arinze Anthony Onwuegbuna, Osita Samuel Umeononihu, Onyedika Promise Anaedu, Odigonma Zinobia Ikpeze, David Chibuike Ikwuka, Henry Ifeanyi Nwaolisa, Ekene Agatha Emeka, Jude Ogechukwu Okoye, Ihechinyerem Kelechi Osuagwu, Angela Ogechukwu Ugwu, Toochukwu Benjamin Ejikeme, Eziamaka Pauline Ezenkwele, Chijioke Ogomegbunam Ezeigwe, Malarchy Ekwunife Nwankwo, Gerald Okanandu Udigwe, Joseph Ifeanyichukwu Ikechebelu, Grace Agbaeze, Chukwuebuka Divine Nwanja, Ahizechukwu Chigoziem Eke
Background and objectives: Coronavirus disease 2019 (COVID-19) is a pandemic that has become a major source of morbidity and mortality worldwide, affecting the physical and mental health of individuals influencing reproduction. Despite the threat, it poses to maternal health in sub-Saharan Africa and Nigeria, there is little or no data on the impact it has on fertility, conception, gestation and birth. To compare the birth rate between pre-COVID and COVID times using selected months of the year.
Materials and methods: This was a secondary analysis of cross-sectional analytical study data from the birth registries of three tertiary hospitals, comparing two years [2019 (Pre-COVID)] versus [2020 (COVID era)] using three months of the year (October to December). The data relied upon was obtained from birth registries in three busy maternity clinics all within tertiary hospitals in South-East Nigeria and we aimed at discussing the potential impacts of COVID-19 on fertility in Nigeria. The secondary outcome measures were; mode of delivery, booking status of the participants, maternal age and occupation.
Results: There was a significant decrease in tertiary-hospital based birth rate by 92 births (P = 0.0009; 95% CI: -16.0519 to -4.1481) among mothers in all the three hospitals in 2020 during the COVID period (post lockdown months) of October to December. There was a significant difference in the mode of delivery for mothers (P = 0.0096) with a 95% confidence interval of 1.0664 to 1.5916, as more gave birth through vaginal delivery during the 2020 COVID-19 period than pre-COVID-19.
Conclusion: Tertiary-hospital based birth rates were reduced during the pandemic. Our multi-centre study extrapolated on possible factors that may have played a role in this decline in their birth rate, which includes but is not limited to; decreased access to hospital care due to the total lockdowns/curfews and worsening inflation and economic recession in the country.
{"title":"The impact of COVID-19 on the birth rate in Nigeria: a report from population-based registries.","authors":"Charlotte Blanche Oguejiofor, Kenechi Miracle Ebubechukwu, George Uchenna Eleje, Emmanuel Onyebuchi Ugwu, Joseph Tochukwu Enebe, Kingsley Emeka Ekwuazi, Chukwuemeka Chukwubuikem Okoro, Boniface Chukwuneme Okpala, Charles Chukwunomunso Okafor, Nnanyelugo Chima Ezeora, Emeka Ifeanyi Iloghalu, Chidebe Christian Anikwe, Chigozie Geoffrey Okafor, Polycarp Uchenna Agu, Emeka Philip Igbodike, Iffiyeosuo Dennis Ake, Arinze Anthony Onwuegbuna, Osita Samuel Umeononihu, Onyedika Promise Anaedu, Odigonma Zinobia Ikpeze, David Chibuike Ikwuka, Henry Ifeanyi Nwaolisa, Ekene Agatha Emeka, Jude Ogechukwu Okoye, Ihechinyerem Kelechi Osuagwu, Angela Ogechukwu Ugwu, Toochukwu Benjamin Ejikeme, Eziamaka Pauline Ezenkwele, Chijioke Ogomegbunam Ezeigwe, Malarchy Ekwunife Nwankwo, Gerald Okanandu Udigwe, Joseph Ifeanyichukwu Ikechebelu, Grace Agbaeze, Chukwuebuka Divine Nwanja, Ahizechukwu Chigoziem Eke","doi":"10.53388/idr2023004","DOIUrl":"10.53388/idr2023004","url":null,"abstract":"<p><strong>Background and objectives: </strong>Coronavirus disease 2019 (COVID-19) is a pandemic that has become a major source of morbidity and mortality worldwide, affecting the physical and mental health of individuals influencing reproduction. Despite the threat, it poses to maternal health in sub-Saharan Africa and Nigeria, there is little or no data on the impact it has on fertility, conception, gestation and birth. To compare the birth rate between pre-COVID and COVID times using selected months of the year.</p><p><strong>Materials and methods: </strong>This was a secondary analysis of cross-sectional analytical study data from the birth registries of three tertiary hospitals, comparing two years [2019 (Pre-COVID)] versus [2020 (COVID era)] using three months of the year (October to December). The data relied upon was obtained from birth registries in three busy maternity clinics all within tertiary hospitals in South-East Nigeria and we aimed at discussing the potential impacts of COVID-19 on fertility in Nigeria. The secondary outcome measures were; mode of delivery, booking status of the participants, maternal age and occupation.</p><p><strong>Results: </strong>There was a significant decrease in tertiary-hospital based birth rate by 92 births (<i>P</i> = 0.0009; 95% CI: -16.0519 to -4.1481) among mothers in all the three hospitals in 2020 during the COVID period (post lockdown months) of October to December. There was a significant difference in the mode of delivery for mothers (<i>P</i> = 0.0096) with a 95% confidence interval of 1.0664 to 1.5916, as more gave birth through vaginal delivery during the 2020 COVID-19 period than pre-COVID-19.</p><p><strong>Conclusion: </strong>Tertiary-hospital based birth rates were reduced during the pandemic. Our multi-centre study extrapolated on possible factors that may have played a role in this decline in their birth rate, which includes but is not limited to; decreased access to hospital care due to the total lockdowns/curfews and worsening inflation and economic recession in the country.</p>","PeriodicalId":93445,"journal":{"name":"Infectious diseases research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659584/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70810327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Generation of oxidants and their role in the metabolism of oxygen in the survivability of filarial parasite Setaria digitata in cattle: a possible intervention strategy","authors":"Kochukunju Pillai Jayakumar, K. G. Nevin","doi":"10.53388/idr2023006","DOIUrl":"https://doi.org/10.53388/idr2023006","url":null,"abstract":"","PeriodicalId":93445,"journal":{"name":"Infectious diseases research","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70810432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Holy basil (Tulsi, Ocimum sanctum ) is considered to be a pious plant. It is used not only in many of the rituals of Hindus but is also known for its innumerable medicinal qualities. Holy basil leaves (HBLs) are often consumed raw thus it is pertinent to detect the bacteria on Tulsi leaves. This study was conducted to understand the diversity of the aerobically growing microbiome of edible holy basil leaves. A total of 112 samples of leaves were collected from households of six localities in and around Bareilly, India for detecting culturable bacteria growing aerobically. A sum of 579 bacterial isolates belonging to 106 different species was identified. Pantoea agglomerans isolates were detected in 43 samples followed by isolates
{"title":"The Assessment of Good and Bad Bacteria in Holy Basil (Ocimum sanctum) Leaves","authors":"Bhoj R Singh, Mudit Chandra, Himani Agri, Ravichandran Karthikeyan, Akanksha Yadav, Varsh Jayakumar","doi":"10.53388/idr2023017","DOIUrl":"https://doi.org/10.53388/idr2023017","url":null,"abstract":"Holy basil (Tulsi, Ocimum sanctum ) is considered to be a pious plant. It is used not only in many of the rituals of Hindus but is also known for its innumerable medicinal qualities. Holy basil leaves (HBLs) are often consumed raw thus it is pertinent to detect the bacteria on Tulsi leaves. This study was conducted to understand the diversity of the aerobically growing microbiome of edible holy basil leaves. A total of 112 samples of leaves were collected from households of six localities in and around Bareilly, India for detecting culturable bacteria growing aerobically. A sum of 579 bacterial isolates belonging to 106 different species was identified. Pantoea agglomerans isolates were detected in 43 samples followed by isolates","PeriodicalId":93445,"journal":{"name":"Infectious diseases research","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136367237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A mini review and hypothesis for coronavirus detection using photonics: surface enhanced Raman scattering and fluorescence resonance energy transfer","authors":"Akshat D. Modi, A. Yang, Akriti Sharma","doi":"10.53388/idr2023003","DOIUrl":"https://doi.org/10.53388/idr2023003","url":null,"abstract":"","PeriodicalId":93445,"journal":{"name":"Infectious diseases research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70810716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chijioke Ogomegbunam Ezeigwe, G. Eleje, C. Anikwe, D. Ikwuka, B. Okpala, K. C. Irikannu, E. Igbodike, Emmanuel I. Umegbolu, N. Uzoewulu, O. Onaadepo, M. E. Nwankwo, O. Ogelle, C. Nworgu, J. Uzoigwe, Ifeoma Frances Okwuonu, C. Chigbo, L. U. Okafor, C. Anyaoku, C. Ezeama, C. Oguejiofor, J. Ikechebelu
{"title":"Effectiveness of Gardnerella vaginalis culture and Nugent scoring in identifying bacterial vaginosis in pregnant women","authors":"Chijioke Ogomegbunam Ezeigwe, G. Eleje, C. Anikwe, D. Ikwuka, B. Okpala, K. C. Irikannu, E. Igbodike, Emmanuel I. Umegbolu, N. Uzoewulu, O. Onaadepo, M. E. Nwankwo, O. Ogelle, C. Nworgu, J. Uzoigwe, Ifeoma Frances Okwuonu, C. Chigbo, L. U. Okafor, C. Anyaoku, C. Ezeama, C. Oguejiofor, J. Ikechebelu","doi":"10.53388/idr2023010","DOIUrl":"https://doi.org/10.53388/idr2023010","url":null,"abstract":"","PeriodicalId":93445,"journal":{"name":"Infectious diseases research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70810914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retrospective analysis of early COVID-19 vaccine efficacy in older individuals receiving primary cycle, first booster and second booster","authors":"C. Mattiuzzi, B. Henry, G. Lippi","doi":"10.53388/idr2023001","DOIUrl":"https://doi.org/10.53388/idr2023001","url":null,"abstract":"","PeriodicalId":93445,"journal":{"name":"Infectious diseases research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70810747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bhoj R. Singh, D. K. Sinha, V. Jayakumar, H. Agri, A. Yadav, R. Karthikeyan
{"title":"Effect of picking multiple colonies on antimicrobial susceptibility diagnostic outcome in a clinical bacteriology setting","authors":"Bhoj R. Singh, D. K. Sinha, V. Jayakumar, H. Agri, A. Yadav, R. Karthikeyan","doi":"10.53388/idr2023008","DOIUrl":"https://doi.org/10.53388/idr2023008","url":null,"abstract":"","PeriodicalId":93445,"journal":{"name":"Infectious diseases research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70811139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To explore factors related to postoperative pulmonary infection in lung cancer patients after recovery from COVID-19 and to provide methods for preventing and reducing the incidence of postoperative lung infection in patients with lung cancer. Methods: A total of 92 patients who underwent lung cancer surgery in the Department of Thoracic and Cardiac Surgery of Yichang Central People’s Hospital from January 28, 2023, to March 3, 2023, were selected. They were divided into a pulmonary infection group (47 cases) and a nonpulmonary infection group (45 cases) according to whether pulmonary infection occurred. General clinical data of patients were collected and collated to analyse the related influencing factors of pulmonary infection in lung cancer patients after recovery from COVID-19. Results: Univariate analysis showed that patient age (≥ 60 years), fever after COVID-19 infection, oral and laryngeal symptoms, digestive tract symptoms, neurological symptoms, long-term smoking history, hypertension history, and operation time (≥ 3 h) were correlated with pulmonary infection (all P < 0.05). There was no significant correlation between postoperative pulmonary infection and sex, ocular, nasal and tongue symptoms, systemic symptoms, duration of COVID-19, COPD, lobectomy site, incision pain, mechanical ventilation time (≥ 6 h), drainage tube retention time (3 d), surgical method( P > 0.05). Logistic multivariate analysis showed that age (≥60 years old), long operation time (≥ 3 h) and long-term smoking history were independent influencing factors for postoperative pulmonary infection in patients with radical resection of lung cancer ( P > 0.05). Conclusion: In this study, older age (≥ 60 years old), long-term smoking history, and long operation time (≥ 3 h) were risk factors for pulmonary infection after lung cancer surgery. In the future, active treatment measures can be taken to address these risk factors during the perioperative period to reduce the incidence of postoperative pulmonary infection.
{"title":"Analysis of factors related to postoperative pulmonary infection in lung cancer patients after recovery from COVID-19","authors":"Ling Wang, Hailian Li, Lili Qin, Caiquin Liu","doi":"10.53388/idr2023014","DOIUrl":"https://doi.org/10.53388/idr2023014","url":null,"abstract":"Objective: To explore factors related to postoperative pulmonary infection in lung cancer patients after recovery from COVID-19 and to provide methods for preventing and reducing the incidence of postoperative lung infection in patients with lung cancer. Methods: A total of 92 patients who underwent lung cancer surgery in the Department of Thoracic and Cardiac Surgery of Yichang Central People’s Hospital from January 28, 2023, to March 3, 2023, were selected. They were divided into a pulmonary infection group (47 cases) and a nonpulmonary infection group (45 cases) according to whether pulmonary infection occurred. General clinical data of patients were collected and collated to analyse the related influencing factors of pulmonary infection in lung cancer patients after recovery from COVID-19. Results: Univariate analysis showed that patient age (≥ 60 years), fever after COVID-19 infection, oral and laryngeal symptoms, digestive tract symptoms, neurological symptoms, long-term smoking history, hypertension history, and operation time (≥ 3 h) were correlated with pulmonary infection (all P < 0.05). There was no significant correlation between postoperative pulmonary infection and sex, ocular, nasal and tongue symptoms, systemic symptoms, duration of COVID-19, COPD, lobectomy site, incision pain, mechanical ventilation time (≥ 6 h), drainage tube retention time (3 d), surgical method( P > 0.05). Logistic multivariate analysis showed that age (≥60 years old), long operation time (≥ 3 h) and long-term smoking history were independent influencing factors for postoperative pulmonary infection in patients with radical resection of lung cancer ( P > 0.05). Conclusion: In this study, older age (≥ 60 years old), long-term smoking history, and long operation time (≥ 3 h) were risk factors for pulmonary infection after lung cancer surgery. In the future, active treatment measures can be taken to address these risk factors during the perioperative period to reduce the incidence of postoperative pulmonary infection.","PeriodicalId":93445,"journal":{"name":"Infectious diseases research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70811264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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