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The impact of COVID-19 on the birth rate in Nigeria: a report from population-based registries. 2019冠状病毒病对尼日利亚出生率的影响:基于人口登记的报告。
Pub Date : 2023-02-25 Epub Date: 2023-02-15 DOI: 10.53388/idr2023004
Charlotte Blanche Oguejiofor, Kenechi Miracle Ebubechukwu, George Uchenna Eleje, Emmanuel Onyebuchi Ugwu, Joseph Tochukwu Enebe, Kingsley Emeka Ekwuazi, Chukwuemeka Chukwubuikem Okoro, Boniface Chukwuneme Okpala, Charles Chukwunomunso Okafor, Nnanyelugo Chima Ezeora, Emeka Ifeanyi Iloghalu, Chidebe Christian Anikwe, Chigozie Geoffrey Okafor, Polycarp Uchenna Agu, Emeka Philip Igbodike, Iffiyeosuo Dennis Ake, Arinze Anthony Onwuegbuna, Osita Samuel Umeononihu, Onyedika Promise Anaedu, Odigonma Zinobia Ikpeze, David Chibuike Ikwuka, Henry Ifeanyi Nwaolisa, Ekene Agatha Emeka, Jude Ogechukwu Okoye, Ihechinyerem Kelechi Osuagwu, Angela Ogechukwu Ugwu, Toochukwu Benjamin Ejikeme, Eziamaka Pauline Ezenkwele, Chijioke Ogomegbunam Ezeigwe, Malarchy Ekwunife Nwankwo, Gerald Okanandu Udigwe, Joseph Ifeanyichukwu Ikechebelu, Grace Agbaeze, Chukwuebuka Divine Nwanja, Ahizechukwu Chigoziem Eke

Background and objectives: Coronavirus disease 2019 (COVID-19) is a pandemic that has become a major source of morbidity and mortality worldwide, affecting the physical and mental health of individuals influencing reproduction. Despite the threat, it poses to maternal health in sub-Saharan Africa and Nigeria, there is little or no data on the impact it has on fertility, conception, gestation and birth. To compare the birth rate between pre-COVID and COVID times using selected months of the year.

Materials and methods: This was a secondary analysis of cross-sectional analytical study data from the birth registries of three tertiary hospitals, comparing two years [2019 (Pre-COVID)] versus [2020 (COVID era)] using three months of the year (October to December). The data relied upon was obtained from birth registries in three busy maternity clinics all within tertiary hospitals in South-East Nigeria and we aimed at discussing the potential impacts of COVID-19 on fertility in Nigeria. The secondary outcome measures were; mode of delivery, booking status of the participants, maternal age and occupation.

Results: There was a significant decrease in tertiary-hospital based birth rate by 92 births (P = 0.0009; 95% CI: -16.0519 to -4.1481) among mothers in all the three hospitals in 2020 during the COVID period (post lockdown months) of October to December. There was a significant difference in the mode of delivery for mothers (P = 0.0096) with a 95% confidence interval of 1.0664 to 1.5916, as more gave birth through vaginal delivery during the 2020 COVID-19 period than pre-COVID-19.

Conclusion: Tertiary-hospital based birth rates were reduced during the pandemic. Our multi-centre study extrapolated on possible factors that may have played a role in this decline in their birth rate, which includes but is not limited to; decreased access to hospital care due to the total lockdowns/curfews and worsening inflation and economic recession in the country.

背景与目的:2019冠状病毒病(COVID-19)是一种大流行,已成为全球发病率和死亡率的主要来源,影响到影响生殖的个体的身心健康。尽管它对撒哈拉以南非洲和尼日利亚的孕产妇健康构成威胁,但很少或根本没有数据表明它对生育、受孕、妊娠和分娩的影响。使用一年中的选定月份比较COVID前和COVID时间之间的出生率。材料和方法:本研究对来自三家三级医院出生登记的横断面分析研究数据进行了二次分析,使用一年中的三个月(10月至12月)对[2019年(COVID前)]和[2020年(COVID时代)]这两年进行了比较。所依赖的数据来自尼日利亚东南部三级医院内三家繁忙的产科诊所的出生登记处,我们旨在讨论COVID-19对尼日利亚生育率的潜在影响。次要结局指标为;分娩方式、参与者预约状态、产妇年龄及职业。结果:三级医院的出生率明显下降了92例(P = 0.0009;95% CI: -16.0519至-4.1481),在2020年10月至12月的COVID期间(封锁后的几个月),所有三家医院的母亲中。产妇的分娩方式存在显著差异(P = 0.0096), 95%可信区间为1.0664 ~ 1.5916,因为在2020年COVID-19期间,阴道分娩比COVID-19前更多。结论:大流行期间,三级医院的出生率有所下降。我们的多中心研究推断了可能导致出生率下降的因素,包括但不限于;由于全面封锁/宵禁以及该国通货膨胀和经济衰退加剧,获得医院护理的机会减少。
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引用次数: 0
Generation of oxidants and their role in the metabolism of oxygen in the survivability of filarial parasite Setaria digitata in cattle: a possible intervention strategy 氧化剂的产生及其在氧代谢中的作用对牛丝虫虫的生存能力:一种可能的干预策略
Pub Date : 2023-01-01 DOI: 10.53388/idr2023006
Kochukunju Pillai Jayakumar, K. G. Nevin
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引用次数: 0
Cytokines Activation kinetics in lung due to COVID-19 infection COVID-19感染后肺细胞因子激活动力学研究
Pub Date : 2023-01-01 DOI: 10.53388/idr202304011
Abbas Zabihi, Sanaz Pashapour, Y. Hamidi, Sahar Saki, Zahra Ghazazani
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引用次数: 0
The Assessment of Good and Bad Bacteria in Holy Basil (Ocimum sanctum) Leaves 圣罗勒(ocum sanctum)叶片中有益菌和有害菌的鉴定
Pub Date : 2023-01-01 DOI: 10.53388/idr2023017
Bhoj R Singh, Mudit Chandra, Himani Agri, Ravichandran Karthikeyan, Akanksha Yadav, Varsh Jayakumar
Holy basil (Tulsi, Ocimum sanctum ) is considered to be a pious plant. It is used not only in many of the rituals of Hindus but is also known for its innumerable medicinal qualities. Holy basil leaves (HBLs) are often consumed raw thus it is pertinent to detect the bacteria on Tulsi leaves. This study was conducted to understand the diversity of the aerobically growing microbiome of edible holy basil leaves. A total of 112 samples of leaves were collected from households of six localities in and around Bareilly, India for detecting culturable bacteria growing aerobically. A sum of 579 bacterial isolates belonging to 106 different species was identified. Pantoea agglomerans isolates were detected in 43 samples followed by isolates
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引用次数: 0
A mini review and hypothesis for coronavirus detection using photonics: surface enhanced Raman scattering and fluorescence resonance energy transfer 光子学检测冠状病毒的综述与假设:表面增强拉曼散射和荧光共振能量转移
Pub Date : 2023-01-01 DOI: 10.53388/idr2023003
Akshat D. Modi, A. Yang, Akriti Sharma
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引用次数: 0
Effectiveness of Gardnerella vaginalis culture and Nugent scoring in identifying bacterial vaginosis in pregnant women 阴道加德纳菌培养和纽金特评分在鉴别孕妇细菌性阴道病中的有效性
Pub Date : 2023-01-01 DOI: 10.53388/idr2023010
Chijioke Ogomegbunam Ezeigwe, G. Eleje, C. Anikwe, D. Ikwuka, B. Okpala, K. C. Irikannu, E. Igbodike, Emmanuel I. Umegbolu, N. Uzoewulu, O. Onaadepo, M. E. Nwankwo, O. Ogelle, C. Nworgu, J. Uzoigwe, Ifeoma Frances Okwuonu, C. Chigbo, L. U. Okafor, C. Anyaoku, C. Ezeama, C. Oguejiofor, J. Ikechebelu
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引用次数: 0
Retrospective analysis of early COVID-19 vaccine efficacy in older individuals receiving primary cycle, first booster and second booster 首次接种、第一次接种和第二次接种的老年人早期COVID-19疫苗疗效回顾性分析
Pub Date : 2023-01-01 DOI: 10.53388/idr2023001
C. Mattiuzzi, B. Henry, G. Lippi
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引用次数: 0
Effect of picking multiple colonies on antimicrobial susceptibility diagnostic outcome in a clinical bacteriology setting 在临床细菌学环境中,采集多个菌落对抗菌药物敏感性诊断结果的影响
Pub Date : 2023-01-01 DOI: 10.53388/idr2023008
Bhoj R. Singh, D. K. Sinha, V. Jayakumar, H. Agri, A. Yadav, R. Karthikeyan
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引用次数: 0
Analysis of factors related to postoperative pulmonary infection in lung cancer patients after recovery from COVID-19 新型冠状病毒肺炎(COVID-19)术后肺癌患者肺部感染相关因素分析
Pub Date : 2023-01-01 DOI: 10.53388/idr2023014
Ling Wang, Hailian Li, Lili Qin, Caiquin Liu
Objective: To explore factors related to postoperative pulmonary infection in lung cancer patients after recovery from COVID-19 and to provide methods for preventing and reducing the incidence of postoperative lung infection in patients with lung cancer. Methods: A total of 92 patients who underwent lung cancer surgery in the Department of Thoracic and Cardiac Surgery of Yichang Central People’s Hospital from January 28, 2023, to March 3, 2023, were selected. They were divided into a pulmonary infection group (47 cases) and a nonpulmonary infection group (45 cases) according to whether pulmonary infection occurred. General clinical data of patients were collected and collated to analyse the related influencing factors of pulmonary infection in lung cancer patients after recovery from COVID-19. Results: Univariate analysis showed that patient age (≥ 60 years), fever after COVID-19 infection, oral and laryngeal symptoms, digestive tract symptoms, neurological symptoms, long-term smoking history, hypertension history, and operation time (≥ 3 h) were correlated with pulmonary infection (all P < 0.05). There was no significant correlation between postoperative pulmonary infection and sex, ocular, nasal and tongue symptoms, systemic symptoms, duration of COVID-19, COPD, lobectomy site, incision pain, mechanical ventilation time (≥ 6 h), drainage tube retention time (3 d), surgical method( P > 0.05). Logistic multivariate analysis showed that age (≥60 years old), long operation time (≥ 3 h) and long-term smoking history were independent influencing factors for postoperative pulmonary infection in patients with radical resection of lung cancer ( P > 0.05). Conclusion: In this study, older age (≥ 60 years old), long-term smoking history, and long operation time (≥ 3 h) were risk factors for pulmonary infection after lung cancer surgery. In the future, active treatment measures can be taken to address these risk factors during the perioperative period to reduce the incidence of postoperative pulmonary infection.
目的:探讨新型冠状病毒肺炎(COVID-19)术后肺癌患者肺部感染的相关因素,为预防和降低肺癌患者术后肺部感染的发生率提供方法。方法:选取宜昌市中心人民医院心胸外科于2023年1月28日至2023年3月3日行肺癌手术的患者92例。根据是否发生肺部感染分为肺部感染组(47例)和非肺部感染组(45例)。收集整理患者的一般临床资料,分析新冠肺炎康复后肺癌患者肺部感染的相关影响因素。结果:单因素分析显示,患者年龄(≥60岁)、感染后发热、口腔咽喉症状、消化道症状、神经系统症状、长期吸烟史、高血压史、手术时间(≥3 h)与肺部感染相关(均P < 0.05)。术后肺部感染与性别、眼、鼻、舌症状、全身症状、COVID-19病程、COPD、肺叶切除部位、切口疼痛、机械通气时间(≥6 h)、引流管保留时间(3 d)、手术方式无显著相关性(P < 0.05)。Logistic多因素分析显示,年龄(≥60岁)、手术时间长(≥3 h)、长期吸烟史是肺癌根治术后肺部感染的独立影响因素(P < 0.05)。结论:本研究中,年龄较大(≥60岁)、长期吸烟史、手术时间长(≥3 h)是肺癌术后肺部感染的危险因素。今后围手术期可采取积极的治疗措施解决这些危险因素,降低术后肺部感染的发生率。
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引用次数: 0
Evaluation of Antibiotic Use among Inpatients in Surgical Ward at Mbarara Regional Referral Hospital, South-Western Uganda 乌干达西南部姆巴拉拉地区转诊医院外科病房住院患者抗生素使用评估
Pub Date : 2023-01-01 DOI: 10.53388/idr2023009
Odecha Michael, Akankunda Bridget, Kabaana Jude Elizabeth, Kapanga Muhamed, Nabigwo Edward, Tadele Mekuriya Yadesa
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Infectious diseases research
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