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Antimicrobial resistance and challenge post COVID-19 infection COVID-19感染后的抗微生物药物耐药性和挑战
Pub Date : 1900-01-01 DOI: 10.53388/idr20220825015
Arash Soltani
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引用次数: 0
The impact of heavy metals on bacterial tolerance of antibiotic resistance and growth in the aquatic environment of Vietnam 重金属对越南水生环境中细菌耐药性和生长的影响
Pub Date : 1900-01-01 DOI: 10.53388/idr20220101001
Diep The, M. Hoang, Chau Kim, N. Ngoc, N. Thi
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引用次数: 0
Public perceptions about the emerging human monkey pox disease and vaccination in twin cities of Pakistan: a cross-sectional study 巴基斯坦双城公众对新出现的人类猴痘疾病和疫苗接种的看法:一项横断面研究
Pub Date : 1900-01-01 DOI: 10.53388/idr2023005
Humna Baig, U. Javed, Duan Baig
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引用次数: 0
Prevalence of hepatitis B virus infection and associated risk factors among adult females infected with Human Immunodeficiency Virus in Ogun State, Nigeria 尼日利亚奥贡州感染人类免疫缺陷病毒的成年女性中乙型肝炎病毒感染的流行情况及相关危险因素
Pub Date : 1900-01-01 DOI: 10.53388/idr2023013
J. Ihongbe, Seyi S. Enitan, M. O. Dada, O. Ofem, O. Ofem, Effiong Joseph Effiong, O. Kemiki, Amarachi Favour Ogbonna
Background: Hepatitis B virus (HBV) infection is prevalent in sub-Saharan Africa, including Nigeria, and is frequently observed in individuals co-infected with human immunodeficiency virus (HIV). Objective: This study aims to evaluate the prevalence of serological markers for hepatitis B virus and identify the associated risk factors among women with HIV undergoing highly active antiretroviral therapy (HAART) in Ogun State, Nigeria. Methods: Ethical approval was obtained from the Babcock University Health Research Ethics Committee (BUHREC) to recruit a total of 110 adult women infected with HIV, receiving treatment at the HIV clinics of Babcock University Teaching Hospital (BUTH) in Ilishan-Remo and General Hospital in Ijebu-Ode, both located in Ogun State, Nigeria. The participants’ HIV status were confirmed using three rapid diagnostic kits: Determine (Abbott Laboratories, Tokyo, Japan), Unigold HIV (Trinity Biotech Plc Bray, Co. Wicklow, Ireland), and 1/2 Stat Pak (Abbott Laboratories, Tokyo, Japan) (Chembio Diagnostic Systems, New York, USA). Additionally, an HBV 5 in 1 Panel manufactured by Innovation Biotechnology Co., Ltd in Beijing, China, was employed to detect HBV markers qualitatively in serum samples. Results: Out of the 110 subjects that voluntarily participated in the study, 4 (3.6%) tested positive for HBsAg, 2 (1.8%) tested positive for HBsAb, 81 (73.6%) tested positive for HBeAg, 3 (2.7%) tested positive for HBeAb, and 65 (59.1%) tested positive for HBcAb. There was no significant correlation between the occurrence of HBsAg and the socio-demographic characteristics of the participants ( P > 0.05). Various risk factors were identified, including lack of knowledge about HBV, absence of HBV vaccination history, history of blood transfusion, organ transplant, and engaging in unprotected sex, among others. Conclusion: The findings highlight the presence of HBV infection among HIV-positive women undergoing HAART in Ogun State, Nigeria, particularly within the age groups of 18–25 years and 26–30 years. These results emphasize the necessity for continuous and targeted public health interventions among this specific population.
背景:乙型肝炎病毒(HBV)感染在包括尼日利亚在内的撒哈拉以南非洲很普遍,并且经常在人类免疫缺陷病毒(HIV)合并感染的个体中观察到。目的:本研究旨在评估尼日利亚奥贡州接受高活性抗逆转录病毒治疗(HAART)的女性乙肝病毒血清学标志物的流行情况,并确定相关危险因素。方法:获得巴布科克大学健康研究伦理委员会(BUHREC)的伦理批准,招募总共110名感染艾滋病毒的成年妇女,在尼日利亚奥根州伊利山-雷莫的巴布科克大学教学医院(BUTH)和伊杰布-奥德总医院的艾滋病毒诊所接受治疗。使用三种快速诊断试剂盒确认参与者的HIV状态:确定(雅培实验室,东京,日本),Unigold HIV (Trinity Biotech Plc Bray, Co. Wicklow,爱尔兰)和1/2 Stat Pak(雅培实验室,东京,日本)(Chembio诊断系统,纽约,美国)。此外,采用中国北京创新生物技术有限公司生产的HBV 5 in 1 Panel对血清样本中的HBV标志物进行定性检测。结果:在110名自愿参加研究的受试者中,HBsAg阳性4人(3.6%),HBsAb阳性2人(1.8%),HBeAg阳性81人(73.6%),HBeAb阳性3人(2.7%),HBcAb阳性65人(59.1%)。HBsAg的发生与受试者的社会人口学特征无显著相关性(P < 0.05)。确定了各种危险因素,包括缺乏HBV知识、没有HBV疫苗接种史、输血史、器官移植史和从事无保护的性行为等。结论:研究结果强调了在尼日利亚奥贡州接受HAART治疗的艾滋病毒阳性妇女中存在HBV感染,特别是在18-25岁和26-30岁年龄组中。这些结果强调了在这一特定人群中进行持续和有针对性的公共卫生干预的必要性。
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Infectious diseases research
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