Pub Date : 2021-09-01DOI: 10.3329/jcmcta.v32i1.66535
S. Das, Pranay Kumar Datta
Background : Different diagnostic tools are available for assessment of post operative outcomes of thyroid surgery. This study was done to reach a consensus and to find out the best diagnostic tool for assessment of post operative complications of thyroid surgery. Materials and methods : A cross sectional study was carried out in the Medical Centre Hospital Between July 2016 to June 2017. Total 50 patients were included in the study, where post operative complications of patients were assessed, studied and enrolled. To assess the post operative outcomes of patients undergoing thyroid surgery. Data were analyzed and presented as both qualitative and quantitative data as applicable using SPSS version 20. The quantitative data were analyzed by mean, standard deviation. The qualitative data were analyzed by Mc NEMAR test (Mc NEMAR χ2 test). For all analytical test, the level of significance was set at 0.05 and p value equal or less then 0.05 was considered as significant, p value more than 0.05 was considered as not significant. Results : Fifty patients were selected for the study who were treated by Thyroidectomy. The mean patient's age at the time of surgery was 40.9±9.1 years ranged from 10 to 60 years. Data were collected in a prescribed data collection sheet. Then all data were compiled and analyzed. Result: 14% of the patients had complications, of them 2% had transient hypoparathyroidism, 4% had haemorrhage, 2% had temporary Recurrent Laryngeal Nerve (RLN) palsy and 2% had permanent recurrent laryngeal nerve palsy, 2% had Superior Laryngeal Nerve (SLN) palsy & 2% had wound infection. Improved surgical techniques and proper management of complications reduce the postoperative morbidity and mortality of thyroid surgery. Conclusions: Different types of complications may occur following thyroid surgery. In spite of all measures, keen observation in postoperative period is very important to find out the complications for early intervention. JCMCTA 2021 ; 32 (1) : 44-47
背景:不同的诊断工具可用于评估甲状腺手术后的结果。本研究旨在达成共识，寻找评估甲状腺手术术后并发症的最佳诊断工具。材料与方法:横断面研究于2016年7月至2017年6月在医学中心医院进行。本研究共纳入50例患者，对患者术后并发症进行评估、研究和入组。目的:评价甲状腺手术患者的术后预后。使用SPSS version 20对数据进行定性和定量分析。定量资料采用均数、标准差进行分析。定性资料采用Mc NEMAR检验(Mc NEMAR χ2检验)。所有分析检验的显著性水平设为0.05,p值等于或小于0.05为显著，p值大于0.05为不显著。结果:选择50例行甲状腺切除术的患者作为研究对象。患者手术时的平均年龄为40.9±9.1岁，年龄范围从10岁到60岁。在规定的数据收集表中收集数据。然后对所有数据进行整理和分析。结果:14%的患者出现并发症，其中短暂性甲状旁腺功能低下占2%，出血占4%，暂时性喉返神经麻痹占2%，永久性喉返神经麻痹占2%，喉上神经麻痹占2%，伤口感染占2%。手术技术的改进和并发症的合理处理降低了甲状腺手术的术后发病率和死亡率。结论:甲状腺手术后可能出现不同类型的并发症。尽管采取了各种措施，但术后的敏锐观察对于发现并发症进行早期干预是非常重要的。Jcmcta 2021;32 (1): 44-47
{"title":"Assessment of Complications following Thyroid Surgery","authors":"S. Das, Pranay Kumar Datta","doi":"10.3329/jcmcta.v32i1.66535","DOIUrl":"https://doi.org/10.3329/jcmcta.v32i1.66535","url":null,"abstract":"Background : Different diagnostic tools are available for assessment of post operative outcomes of thyroid surgery. This study was done to reach a consensus and to find out the best diagnostic tool for assessment of post operative complications of thyroid surgery. \u0000Materials and methods : A cross sectional study was carried out in the Medical Centre Hospital Between July 2016 to June 2017. Total 50 patients were included in the study, where post operative complications of patients were assessed, studied and enrolled. To assess the post operative outcomes of patients undergoing thyroid surgery. Data were analyzed and presented as both qualitative and quantitative data as applicable using SPSS version 20. The quantitative data were analyzed by mean, standard deviation. The qualitative data were analyzed by Mc NEMAR test (Mc NEMAR χ2 test). For all analytical test, the level of significance was set at 0.05 and p value equal or less then 0.05 was considered as significant, p value more than 0.05 was considered as not significant. \u0000Results : Fifty patients were selected for the study who were treated by Thyroidectomy. The mean patient's age at the time of surgery was 40.9±9.1 years ranged from 10 to 60 years. Data were collected in a prescribed data collection sheet. Then all data were compiled and analyzed. Result: 14% of the patients had complications, of them 2% had transient hypoparathyroidism, 4% had haemorrhage, 2% had temporary Recurrent Laryngeal Nerve (RLN) palsy and 2% had permanent recurrent laryngeal nerve palsy, 2% had Superior Laryngeal Nerve (SLN) palsy & 2% had wound infection. Improved surgical techniques and proper management of complications reduce the postoperative morbidity and mortality of thyroid surgery. \u0000Conclusions: Different types of complications may occur following thyroid surgery. In spite of all measures, keen observation in postoperative period is very important to find out the complications for early intervention. \u0000JCMCTA 2021 ; 32 (1) : 44-47","PeriodicalId":93458,"journal":{"name":"Journal of Chittagong Medical College Teachers' Association","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89440066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-01DOI: 10.3329/jcmcta.v32i1.66560
Hiranmoy Dutta, Mohammad Mahmudur Rahman Chowdhury, Mohammed Maksudul Karim, T. Shams, Rivu Chakraborty, Pragwa Permita Chakraborty, S. Kabir, Mahmud Hassan Arif, Shusmita Saha, S. Paul
Background: Studies elsewhere in the world observed that, chest Computed Tomography (CT) scoring could help to stratify patient’s risk and predict short-term outcome of patients with COVID-19 pneumonia. But report from Bangladesh in this regard is in short supply. This study was aimed to investigate the relationship between the percentage of lung involvement as defined by CT scan score and outcome of COVID-19 patients admitted in a COVID dedicated hospital of Bangladesh. Materials and methods: This prospective observational study included 103 RTPCR confirmed COVID19 patients admitted in Chittagong Medical College Hospital (CMCH). All patients had a non-contrast HRCT scan done at presentation. Severity of CT score was categorized as Mild: score 7 or less, Moderate: score 8–17 and severe: score 18 or more. Outcome data in terms of oxygen requirement, length of hospital stay and in-hospital mortality were collected. Results: The mean age was 53.12 ± 12.69 years (58.3% males, 41.7% females). CT severity score was found to be positively correlated with clinical category of COVID-19. The oxygen requirements and length of hospital stay were increasing with the increase in scan severity. Multivariate analysis revealed that CT severity score was the only significant predictor for death (Odds ratio: 1.228; 95% CI:1.019-1.48). Conclusions: Our data suggest that chest CT scoring system can aid in predicting COVID-19 disease outcome and significantly correlates with oxygen requirements in a sample of Bangladeshi COVID-19 patients. JCMCTA 2021 ; 32 (1) : 78-82
{"title":"Correlation between Chest CT Score and Outcome of COVID-19 Patients: Experience from A COVID Hospital of Chattogram, Bangladesh","authors":"Hiranmoy Dutta, Mohammad Mahmudur Rahman Chowdhury, Mohammed Maksudul Karim, T. Shams, Rivu Chakraborty, Pragwa Permita Chakraborty, S. Kabir, Mahmud Hassan Arif, Shusmita Saha, S. Paul","doi":"10.3329/jcmcta.v32i1.66560","DOIUrl":"https://doi.org/10.3329/jcmcta.v32i1.66560","url":null,"abstract":"Background: Studies elsewhere in the world observed that, chest Computed Tomography (CT) scoring could help to stratify patient’s risk and predict short-term outcome of patients with COVID-19 pneumonia. But report from Bangladesh in this regard is in short supply. This study was aimed to investigate the relationship between the percentage of lung involvement as defined by CT scan score and outcome of COVID-19 patients admitted in a COVID dedicated hospital of Bangladesh. \u0000Materials and methods: This prospective observational study included 103 RTPCR confirmed COVID19 patients admitted in Chittagong Medical College Hospital (CMCH). All patients had a non-contrast HRCT scan done at presentation. Severity of CT score was categorized as Mild: score 7 or less, Moderate: score 8–17 and severe: score 18 or more. Outcome data in terms of oxygen requirement, length of hospital stay and in-hospital mortality were collected. \u0000Results: The mean age was 53.12 ± 12.69 years (58.3% males, 41.7% females). CT severity score was found to be positively correlated with clinical category of COVID-19. The oxygen requirements and length of hospital stay were increasing with the increase in scan severity. Multivariate analysis revealed that CT severity score was the only significant predictor for death (Odds ratio: 1.228; 95% CI:1.019-1.48). \u0000Conclusions: Our data suggest that chest CT scoring system can aid in predicting COVID-19 disease outcome and significantly correlates with oxygen requirements in a sample of Bangladeshi COVID-19 patients. \u0000JCMCTA 2021 ; 32 (1) : 78-82","PeriodicalId":93458,"journal":{"name":"Journal of Chittagong Medical College Teachers' Association","volume":"243 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78345231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-01DOI: 10.3329/jcmcta.v32i1.66527
Syeda Shahnoor Hasina Mamtaz, Abu Hena Md Saiful Karim Chowdhury
Background: Neonatal sepsis is an important public health problem with a high morbidity and mortality. Globally, it has been reported that preterm newborns have a 13 times greater risk of death than full term newborn babies. Clinical, hematological parameters and the spectrum of organisms causing neonatal sepsis may vary between term and preterm. Present study is a good opportunity to evaluate clinical, haematological & bacteriological profile of neonatal sepsis in preterm & term. Materials and methods: This hospital based observational and comparative study was carried out in Special Care Newborn Unit (SCANU) of Chittagong Medical College Hospital where a total of 100 clinically suspected neonatal sepsis cases was enrolled, out of which 50 were preterm and 50 term neonates. Clinical, hematological and bacteriological profiles were compared between two groups. Results: Hypothermia was an important clinical feature occurring in 70.0% preterm and 16.0% term cases. Mean platelet count was 1.04±0.73 lacs/cmm in preterm and 1.52±0.78 lacs/cmm in term cases. In term and preterm neonates CRP were observed to be 39.42±32.99mg/L and 26.20±22.25 mg/L (p=0.021). Klebsiella species was the predominant isolated bacteria in both groups, showing 16.0% in preterm and 14.0% in term cases, followed by S. aureus, Acinetobacter species and Candida species. Conclusion: Neonatal sepsis is an important cause of morbidity and mortality. There is need of large scale studies, in hope of developing a better prevention policy in both term and preterm babies. JCMCTA 2021 ; 32 (1) : 21-25
{"title":"Comparison of Clinical, Hematological and Bacteriological Profile of Neonatal Sepsis between Term and Preterm Babies","authors":"Syeda Shahnoor Hasina Mamtaz, Abu Hena Md Saiful Karim Chowdhury","doi":"10.3329/jcmcta.v32i1.66527","DOIUrl":"https://doi.org/10.3329/jcmcta.v32i1.66527","url":null,"abstract":"Background: Neonatal sepsis is an important public health problem with a high morbidity and mortality. Globally, it has been reported that preterm newborns have a 13 times greater risk of death than full term newborn babies. Clinical, hematological parameters and the spectrum of organisms causing neonatal sepsis may vary between term and preterm. Present study is a good opportunity to evaluate clinical, haematological & bacteriological profile of neonatal sepsis in preterm & term. \u0000Materials and methods: This hospital based observational and comparative study was carried out in Special Care Newborn Unit (SCANU) of Chittagong Medical College Hospital where a total of 100 clinically suspected neonatal sepsis cases was enrolled, out of which 50 were preterm and 50 term neonates. Clinical, hematological and bacteriological profiles were compared between two groups. \u0000Results: Hypothermia was an important clinical feature occurring in 70.0% preterm and 16.0% term cases. Mean platelet count was 1.04±0.73 lacs/cmm in preterm and 1.52±0.78 lacs/cmm in term cases. In term and preterm neonates CRP were observed to be 39.42±32.99mg/L and 26.20±22.25 mg/L (p=0.021). Klebsiella species was the predominant isolated bacteria in both groups, showing 16.0% in preterm and 14.0% in term cases, followed by S. aureus, Acinetobacter species and Candida species. \u0000Conclusion: Neonatal sepsis is an important cause of morbidity and mortality. There is need of large scale studies, in hope of developing a better prevention policy in both term and preterm babies. \u0000JCMCTA 2021 ; 32 (1) : 21-25","PeriodicalId":93458,"journal":{"name":"Journal of Chittagong Medical College Teachers' Association","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87401863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-01DOI: 10.3329/jcmcta.v32i1.66559
M. Akhter, N. Noor, M. Begum, Shahin Akhter, Arunima Datta
Background: Pollutants exerted from different industries are hazardous for both employees and the environment. Though cement industry is playing a key role in economic growth but is a major source of air pollution. Its exposure affects pulmonary functions due to alteration of structural and functional properties of lung. Peak Expiratory Flow Rate (PEFR) is a simple, less expensive pulmonary function test which can be done by spirometer to detect obstructive changes in the respiratory tract.This study is aimed to assess the effect of cement dust on peak expiratory flow rate of workers, those who are exposed to cement dust directly in cement factory. Materials and methods: This case control study was conducted in the Department of Physiology, Chittagong Medical College, Chattogram in collaboration with Heidelberg Cement Bangladesh Ltd at Chattogram from January 2018 to December 2018. Total 88 male workers with age ranged from 20 to 45 years were included in this study by consecutive sampling method. Case group workers were selected from those who were working at least two years in direct contact of cement dust and control group were from office workers of same factory those who were not in direct contact of cement. 44 subjects were included in each group. A predesigned data collection form was filled up by the researcher,which contained information regarding general physical status, job history, present and past disease, drug history of workers. Individual’s height, weight was measured and BMI was calculated. PEFR was assessed by a portable digital spirometer (Chestgraph HI-101, Japan) in upright sitting posture. After compiling data,statistical analyses were done by using SPSS version Windows 25. Unpaired student's 't' test was done for statistical analysis. Results: PEFR of Control and Case group was 7.84±2.21 L/sec and 5.73±1.79 L/sec respectively. In this study Case group showed significant reduction of PEFR (p<0.001) compared to Control group workers. Conclusion: This study result concluded that occupational exposure to cement dust has deleterious effect on lung which is evident by reduced Peak Expiratory Flow Rate (PEFR) of cement exposed workers. JCMCTA 2021 ; 32 (1) : 72-77
{"title":"Effect of Exposure to Cement Dust on Peak Expiratory Flow Rate of Cement Factory Workers","authors":"M. Akhter, N. Noor, M. Begum, Shahin Akhter, Arunima Datta","doi":"10.3329/jcmcta.v32i1.66559","DOIUrl":"https://doi.org/10.3329/jcmcta.v32i1.66559","url":null,"abstract":"Background: Pollutants exerted from different industries are hazardous for both employees and the environment. Though cement industry is playing a key role in economic growth but is a major source of air pollution. Its exposure affects pulmonary functions due to alteration of structural and functional properties of lung. Peak Expiratory Flow Rate (PEFR) is a simple, less expensive pulmonary function test which can be done by spirometer to detect obstructive changes in the respiratory tract.This study is aimed to assess the effect of cement dust on peak expiratory flow rate of workers, those who are exposed to cement dust directly in cement factory. \u0000Materials and methods: This case control study was conducted in the Department of Physiology, Chittagong Medical College, Chattogram in collaboration with Heidelberg Cement Bangladesh Ltd at Chattogram from January 2018 to December 2018. Total 88 male workers with age ranged from 20 to 45 years were included in this study by consecutive sampling method. Case group workers were selected from those who were working at least two years in direct contact of cement dust and control group were from office workers of same factory those who were not in direct contact of cement. 44 subjects were included in each group. A predesigned data collection form was filled up by the researcher,which contained information regarding general physical status, job history, present and past disease, drug history of workers. Individual’s height, weight was measured and BMI was calculated. PEFR was assessed by a portable digital spirometer (Chestgraph HI-101, Japan) in upright sitting posture. After compiling data,statistical analyses were done by using SPSS version Windows 25. Unpaired student's 't' test was done for statistical analysis. \u0000Results: PEFR of Control and Case group was 7.84±2.21 L/sec and 5.73±1.79 L/sec respectively. In this study Case group showed significant reduction of PEFR (p<0.001) compared to Control group workers. \u0000Conclusion: This study result concluded that occupational exposure to cement dust has deleterious effect on lung which is evident by reduced Peak Expiratory Flow Rate (PEFR) of cement exposed workers. \u0000JCMCTA 2021 ; 32 (1) : 72-77","PeriodicalId":93458,"journal":{"name":"Journal of Chittagong Medical College Teachers' Association","volume":"180 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77541032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-01DOI: 10.3329/jcmcta.v32i1.66533
Sajjad Mohammad Yusuff, A. A. Chowdhury, Md Rakibul Hasan, Abu Khaled Muhammad Iqbal, F. Alam, S.U. Tasmia
Background : Male Breast Cancer (MBC) is a rare disease all over the world accounting for less than 1% of all breast cancers. Histopathologically most of the cases are infiltrating ductal carcinoma. Treatment depends on the stage and biological behavior like ER, PR and HER-2 status of the disease, general condition and other comorbidities of the patient. Like female breast cancer, different modalities like surgery, chemotherapy, radiotherapy, hormone therapy, immunotherapy and targeted therapy are the mainstay of treatment. This analytical study was carried out to see the clinical and biological behavior, risk factors and treatment pattern of the disease. Materials and methods: This analytical study was carried out in the Department of Radiotherapy, Chittagong Medical College Hospital and Centre for Specialized Care and Research Hospital, Chattogram from January 2005 to July 2020. Total 28 numbers of patients of postoperative breast cancer were enrolled in the study. Case records including follow up records were collected for all cases. Clinical, histopathological and molecular biomarker data were analyzed. Results: Majority of the patients (20 in number, 71.43%) belonged to age group 51-70 years. 23 patients (82.14%) were smoker. 19 patients (67.8%) had lump in the left breast. Infiltrating duct cell carcinoma was the dominant histopathological type. More than 90% cases were of this type of histopathology. All the cases presented with axillary lymph node metastases. One patient had second malignancy who was previously diagnosed and treated as a case of lung cancer. Two patients had positive family history of breast cancer. Conclusion: As a rare disease, sample size was very small in this study. Comprehensive multi center studies are needed to better understand this disease. JCMCTA 2021 ; 32 (1) : 35-39
背景:男性乳腺癌(Male Breast Cancer, MBC)在世界范围内是一种罕见的疾病，占所有乳腺癌的不到1%。组织病理学上多数为浸润性导管癌。治疗取决于疾病的分期和生物学行为，如ER、PR和HER-2状态、患者的一般情况和其他合并症。与女性乳腺癌一样，手术、化疗、放疗、激素治疗、免疫治疗和靶向治疗等不同的治疗方式是治疗的主要方式。本分析研究旨在了解该病的临床和生物学行为、危险因素和治疗模式。材料和方法:本分析性研究于2005年1月至2020年7月在吉大港医学院附属医院放射治疗科和Chattogram专科护理和研究医院中心进行。总共有28例乳腺癌术后患者被纳入研究。收集所有病例的病例记录，包括随访记录。分析临床、组织病理学和分子生物标志物数据。结果:51 ~ 70岁年龄组占多数(20例，占71.43%)。吸烟者23例(82.14%)。左乳肿块19例(67.8%)。浸润性导管细胞癌是主要的组织病理类型。90%以上的病例为这种类型的组织病理学。所有病例均表现为腋窝淋巴结转移。一名患者患有第二种恶性肿瘤，他以前被诊断为肺癌并接受治疗。2例患者有乳腺癌家族史。结论:作为一种罕见病，本研究样本量很小。需要全面的多中心研究来更好地了解这种疾病。Jcmcta 2021;32 (1): 35-39
{"title":"Study on Male Breast Cancer","authors":"Sajjad Mohammad Yusuff, A. A. Chowdhury, Md Rakibul Hasan, Abu Khaled Muhammad Iqbal, F. Alam, S.U. Tasmia","doi":"10.3329/jcmcta.v32i1.66533","DOIUrl":"https://doi.org/10.3329/jcmcta.v32i1.66533","url":null,"abstract":"Background : Male Breast Cancer (MBC) is a rare disease all over the world accounting for less than 1% of all breast cancers. Histopathologically most of the cases are infiltrating ductal carcinoma. Treatment depends on the stage and biological behavior like ER, PR and HER-2 status of the disease, general condition and other comorbidities of the patient. Like female breast cancer, different modalities like surgery, chemotherapy, radiotherapy, hormone therapy, immunotherapy and targeted therapy are the mainstay of treatment. This analytical study was carried out to see the clinical and biological behavior, risk factors and treatment pattern of the disease. \u0000Materials and methods: This analytical study was carried out in the Department of Radiotherapy, Chittagong Medical College Hospital and Centre for Specialized Care and Research Hospital, Chattogram from January 2005 to July 2020. Total 28 numbers of patients of postoperative breast cancer were enrolled in the study. Case records including follow up records were collected for all cases. Clinical, histopathological and molecular biomarker data were analyzed. \u0000Results: Majority of the patients (20 in number, 71.43%) belonged to age group 51-70 years. 23 patients (82.14%) were smoker. 19 patients (67.8%) had lump in the left breast. Infiltrating duct cell carcinoma was the dominant histopathological type. More than 90% cases were of this type of histopathology. All the cases presented with axillary lymph node metastases. One patient had second malignancy who was previously diagnosed and treated as a case of lung cancer. Two patients had positive family history of breast cancer. \u0000Conclusion: As a rare disease, sample size was very small in this study. Comprehensive multi center studies are needed to better understand this disease. \u0000JCMCTA 2021 ; 32 (1) : 35-39","PeriodicalId":93458,"journal":{"name":"Journal of Chittagong Medical College Teachers' Association","volume":"104 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80465518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-01DOI: 10.3329/jcmcta.v32i1.66532
S. Afrose, Nazmul Hoque Munna, Md Mahfuzur Rahman, Humayon Kabir, N. Ahmed, A. Malek
Background: Anti depressant drugs are sometimes used to treat neuropathic pain like Postherpetic Neuralgia (PHN) however, their analgesic efficacy is unclear. Venlafaxine is a reasonably well tolerated anti depressant and is a Serotonin Norepinephrine Reuptake Inhibitor (SNRI) and weak noradrenaline reuptake inhibitor. Although not licensed for the treatment of chronic or neuropathic pain in most countries, it is sometimes used for this indication. The present study evaluated the efficacy, tolerability and Quality of Life (QoL) of venlafaxine use for 12 weeks in patients with PHN. Materials and methods: This quasi-experimental (Pretest-posttest design) was conducted in the department of Neurology, Dhaka Medical College Hospital, from July 2012 to June 2013. Four hundred and fifty two patients were included in the study and Venlafaxine extended release tablet (75 to 150 mg) were administeredfor 12 weeks. Pain severity score, pain interference score and QoL score were assessed by a self-rated questionnaire before treatment and at 12 weeks follow-up. Results: Majority of the patients were male (63.7%) with a mean age of 48.1 years. After 12 weeks of Venlafaxine treatment, 330 (73%) patients reported at least 50% relief in pain, whereas three (0.7%) patients did not report any pain relief. Pain was relieved completely in 32 (7.0%) patients. There was a significant decrease in the mean pain severity score, (5.8±2.0 versus 3.6±2.2) and meanpain interference score (4.5±2.0 versus 3.1±1.9) from baseline to 12 weeks. The mean QoL scale score improved significantly from 5.9±1.6 at baseline to 8.0±1.7 at week 12. Only 2.8% (13/452) patients experienced at least one adverse effect during the study period. Conclusion: Venlafaxine was found to be effective, safe and well tolerated in the patients of PHN for relieving pain and improving QoL. Further double blinded randomize study is needed to validate these findings. JCMCTA 2021 ; 32 (1) : 31-34
{"title":"Venlafaxine Extended Release in the Treatment of Post Herpetic Neuralgia: A Quasi-Experimental Study","authors":"S. Afrose, Nazmul Hoque Munna, Md Mahfuzur Rahman, Humayon Kabir, N. Ahmed, A. Malek","doi":"10.3329/jcmcta.v32i1.66532","DOIUrl":"https://doi.org/10.3329/jcmcta.v32i1.66532","url":null,"abstract":"Background: Anti depressant drugs are sometimes used to treat neuropathic pain like Postherpetic Neuralgia (PHN) however, their analgesic efficacy is unclear. Venlafaxine is a reasonably well tolerated anti depressant and is a Serotonin Norepinephrine Reuptake Inhibitor (SNRI) and weak noradrenaline reuptake inhibitor. Although not licensed for the treatment of chronic or neuropathic pain in most countries, it is sometimes used for this indication. The present study evaluated the efficacy, tolerability and Quality of Life (QoL) of venlafaxine use for 12 weeks in patients with PHN. \u0000Materials and methods: This quasi-experimental (Pretest-posttest design) was conducted in the department of Neurology, Dhaka Medical College Hospital, from July 2012 to June 2013. Four hundred and fifty two patients were included in the study and Venlafaxine extended release tablet (75 to 150 mg) were administeredfor 12 weeks. Pain severity score, pain interference score and QoL score were assessed by a self-rated questionnaire before treatment and at 12 weeks follow-up. \u0000Results: Majority of the patients were male (63.7%) with a mean age of 48.1 years. After 12 weeks of Venlafaxine treatment, 330 (73%) patients reported at least 50% relief in pain, whereas three (0.7%) patients did not report any pain relief. Pain was relieved completely in 32 (7.0%) patients. There was a significant decrease in the mean pain severity score, (5.8±2.0 versus 3.6±2.2) and meanpain interference score (4.5±2.0 versus 3.1±1.9) from baseline to 12 weeks. The mean QoL scale score improved significantly from 5.9±1.6 at baseline to 8.0±1.7 at week 12. Only 2.8% (13/452) patients experienced at least one adverse effect during the study period. \u0000Conclusion: Venlafaxine was found to be effective, safe and well tolerated in the patients of PHN for relieving pain and improving QoL. Further double blinded randomize study is needed to validate these findings. \u0000JCMCTA 2021 ; 32 (1) : 31-34","PeriodicalId":93458,"journal":{"name":"Journal of Chittagong Medical College Teachers' Association","volume":"75 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80742723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-01DOI: 10.3329/jcmcta.v32i1.66873
M. Chowdhury
Abstract not available JCMCTA 2021 ; 32 (1) : 1-3
JCMCTA 2021;32 (1): 1-3
{"title":"The Post-Acute COVID-19 Syndrome : A New Emerging Health Issue","authors":"M. Chowdhury","doi":"10.3329/jcmcta.v32i1.66873","DOIUrl":"https://doi.org/10.3329/jcmcta.v32i1.66873","url":null,"abstract":"Abstract not available \u0000JCMCTA 2021 ; 32 (1) : 1-3","PeriodicalId":93458,"journal":{"name":"Journal of Chittagong Medical College Teachers' Association","volume":"73 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77386840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-01DOI: 10.3329/jcmcta.v32i1.66429
R. K. Khan, Rajib Dey Sarker, Md. Nur Hossain Bhuiyan
Background: Due to global rise of awareness and bonafide role of multi sector media towards breast diseases, women are becoming concern of any health issues of breast and many of them are attending breast clinics. Besides breast cancer is the second most common cause of cancer deaths in the world. We confidently rely on the triple assessment protocol comprising clinical, radiological and pathological examination to escort the management schedule in any breast disease. However, benign breast lumps are most commonly found, but association with morbidity has to be checked and evaluated accordingly. This study was aimed to profiling the breast diseases attended in breast clinic of a tertiary care hospital. To evaluate and categorized the patients with breast diseases which are referred to Breast and Endocrine Clinic (BEC) of Shaheed Suhrawardy Medical College Hospital. Materials and methods: This is a cross sectional done in Breast and Endocrine Clinic (BEC) of Shaheed Suhrawardy Medical College Hospital from January 2019 to January 2021.376 patients with breast symptom included in this study.Demographic data, painful breast, nipple discharge, nipple retraction and breast lump were analyzed. Results: During the study period 376 female patients of different age groups underwent in this study who visited the BEC with a breast symptom detected incidentally by themselves or by other physician, lump in 102 individuals. Demographic pictures were framed in the mean age group of patient was 35.1±9.2 where 30% subjects were postmenopausal and the mean BMI picture revealed stat of 22.5±2.1. Among the afore mentioned objects 154 patients complained of painful breast symptoms of which 64 found with bilateral breast pain, 05 with discharge from nipple and 18 with retracted nipple, 3 with symptoms associating axilla.Breast lump were seen in 61 cases out of which 06 malignant cases were sorted whereas 55 patient came up with benign pathologies. Conclusion: History quest, proper methods of clinical examination of breast is and histopathology are the most predominating screening procedure to recognize pathologies in breast. JCMCTA 2021 ; 32 (1) : 9-13
{"title":"Profiling Breast Diseases Attended in Breast Clinic of A Tertiary Care Hospital","authors":"R. K. Khan, Rajib Dey Sarker, Md. Nur Hossain Bhuiyan","doi":"10.3329/jcmcta.v32i1.66429","DOIUrl":"https://doi.org/10.3329/jcmcta.v32i1.66429","url":null,"abstract":"Background: Due to global rise of awareness and bonafide role of multi sector media towards breast diseases, women are becoming concern of any health issues of breast and many of them are attending breast clinics. Besides breast cancer is the second most common cause of cancer deaths in the world. We confidently rely on the triple assessment protocol comprising clinical, radiological and pathological examination to escort the management schedule in any breast disease. However, benign breast lumps are most commonly found, but association with morbidity has to be checked and evaluated accordingly. This study was aimed to profiling the breast diseases attended in breast clinic of a tertiary care hospital. To evaluate and categorized the patients with breast diseases which are referred to Breast and Endocrine Clinic (BEC) of Shaheed Suhrawardy Medical College Hospital. \u0000Materials and methods: This is a cross sectional done in Breast and Endocrine Clinic (BEC) of Shaheed Suhrawardy Medical College Hospital from January 2019 to January 2021.376 patients with breast symptom included in this study.Demographic data, painful breast, nipple discharge, nipple retraction and breast lump were analyzed. \u0000Results: During the study period 376 female patients of different age groups underwent in this study who visited the BEC with a breast symptom detected incidentally by themselves or by other physician, lump in 102 individuals. Demographic pictures were framed in the mean age group of patient was 35.1±9.2 where 30% subjects were postmenopausal and the mean BMI picture revealed stat of 22.5±2.1. Among the afore mentioned objects 154 patients complained of painful breast symptoms of which 64 found with bilateral breast pain, 05 with discharge from nipple and 18 with retracted nipple, 3 with symptoms associating axilla.Breast lump were seen in 61 cases out of which 06 malignant cases were sorted whereas 55 patient came up with benign pathologies. \u0000Conclusion: History quest, proper methods of clinical examination of breast is and histopathology are the most predominating screening procedure to recognize pathologies in breast. \u0000JCMCTA 2021 ; 32 (1) : 9-13","PeriodicalId":93458,"journal":{"name":"Journal of Chittagong Medical College Teachers' Association","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87039661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-01DOI: 10.3329/jcmcta.v32i1.66530
A. Bashiruddin, M. Chowdhury, Biplob Bhattachajee, S. Dhar, I. Mahmud, Md. Sahadat Hossain, A. Rahim
Background: Clinical guidelines recommend that optimal management of Non ST Elevation Acute Coronary Syndrome (NSTE-ACS) should include patient risk stratification. Predicting the anatomical extension of Coronary Artery Disease (CAD) is also potentially useful for clinical decision. The objective of our study was to determine whether the TIMI risk score correlates with the angiographic extent and severity of CAD in patients with NSTE- ACS. Materials and methods: This cross-sectional study was carried out in the Department of Cardiology, Chittagong Medical College Hospital (CMCH) on a total of 200 patients diagnosed with NSTE - ACS. TIMI risk score was calculated for each patient and they were stratified into 3 groups according to the TIMI risk score: low risk (0-2) intermediate risk (3-4) high risk (5-7). The severity of the CAD was assessed by Gensini score. Results: Mean (± SD) age was 53.7 (±10.8) years and 142 (71%) were male. Regarding cardiovascular risk factors, 68.5% had diabetes mellitus, 41.5% had dyslipidaemia, 77.5% had hypertension, 68% were current smoker and 35% had a family history of CAD. The Gensini score was higher in patients at high risk TIMI group. Moreover, there was a signi cant positive correlation between the TIMI and Gensini score (r=0.446). TIMI score can predict significant CAD moderately well (Area under the curve 0.661). Significantly higher proportion of patients with TIMI score more than 4 (65.9%) had significant three vessels CAD compared to patients with TIMI risk score 3-4 (17.9%) and TIMI risk score less than 3 (2%). Conclusion: TIMI score had good predictive value in assessment the severity of CAD in patients with NSTE-ACS JCMCTA 2021 ; 32 (1) : 26-30
{"title":"Association of TIMI Risk Score with Angiographic Severity of Coronary Artery Disease in Patients with Non-ST Elevation Acute Coronary Syndrome","authors":"A. Bashiruddin, M. Chowdhury, Biplob Bhattachajee, S. Dhar, I. Mahmud, Md. Sahadat Hossain, A. Rahim","doi":"10.3329/jcmcta.v32i1.66530","DOIUrl":"https://doi.org/10.3329/jcmcta.v32i1.66530","url":null,"abstract":"Background: Clinical guidelines recommend that optimal management of Non ST Elevation Acute Coronary Syndrome (NSTE-ACS) should include patient risk stratification. Predicting the anatomical extension of Coronary Artery Disease (CAD) is also potentially useful for clinical decision. The objective of our study was to determine whether the TIMI risk score correlates with the angiographic extent and severity of CAD in patients with NSTE- ACS.\u0000Materials and methods: This cross-sectional study was carried out in the Department of Cardiology, Chittagong Medical College Hospital (CMCH) on a total of 200 patients diagnosed with NSTE - ACS. TIMI risk score was calculated for each patient and they were stratified into 3 groups according to the TIMI risk score: low risk (0-2) intermediate risk (3-4) high risk (5-7). The severity of the CAD was assessed by Gensini score.\u0000Results: Mean (± SD) age was 53.7 (±10.8) years and 142 (71%) were male. Regarding cardiovascular risk factors, 68.5% had diabetes mellitus, 41.5% had dyslipidaemia, 77.5% had hypertension, 68% were current smoker and 35% had a family history of CAD. The Gensini score was higher in patients at high risk TIMI group. Moreover, there was a signi cant positive correlation between the TIMI and Gensini score (r=0.446). TIMI score can predict significant CAD moderately well (Area under the curve 0.661). Significantly higher proportion of patients with TIMI score more than 4 (65.9%) had significant three vessels CAD compared to patients with TIMI risk score 3-4 (17.9%) and TIMI risk score less than 3 (2%).\u0000Conclusion: TIMI score had good predictive value in assessment the severity of CAD in patients with NSTE-ACS\u0000JCMCTA 2021 ; 32 (1) : 26-30","PeriodicalId":93458,"journal":{"name":"Journal of Chittagong Medical College Teachers' Association","volume":"65 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89704679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-09-07DOI: 10.3329/jcmcta.v31i1.62626
Shahanara Chowdhury
Abstract not available JCMCTA 2019 ; 31 (1) : 1-3
JCMCTA 2019;31 (1): 1-3
{"title":"COVID – 19: A Clinical Enigma, Prevention Is the Strategy","authors":"Shahanara Chowdhury","doi":"10.3329/jcmcta.v31i1.62626","DOIUrl":"https://doi.org/10.3329/jcmcta.v31i1.62626","url":null,"abstract":"Abstract not available \u0000JCMCTA 2019 ; 31 (1) : 1-3","PeriodicalId":93458,"journal":{"name":"Journal of Chittagong Medical College Teachers' Association","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75049650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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