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Postoperative Respiratory Dysfunction in Patients with Parkinson’s Disease 帕金森病患者术后呼吸功能障碍的研究
Pub Date : 2023-08-03 DOI: 10.36502/2023/asjbccr.6313
X. Wang
This case report presents a 67-year-old female with Parkinson’s disease who underwent deep brain stimulation (DBS) electrode replacement surgery. Following extubation, the patient developed persistent laryngospasm, requiring immediate intervention. Suspecting symptoms similar to levodopa withdrawal, the patient received intravenous propofol and enteral levodopa supplementation, leading to symptom improvement. The case underscores the importance of perioperative management, including timely medication supplementation and DBS functioning, in Parkinson’s patients to prevent neuroleptic malignant syndrome (NMS)-like complications. Anesthesiologists should be vigilant about potential airway issues and NMS in this population and maintain optimal fluid status during surgery. Prompt intervention can prevent irreversible damage and improve patient outcomes.
本病例报告介绍了一位患有帕金森氏症的67岁女性,她接受了脑深部刺激(DBS)电极置换手术。拔管后,患者出现持续性喉痉挛,需要立即干预。疑似症状类似于左旋多巴戒断,患者接受了静脉注射丙泊酚和肠内补充左旋多巴,导致症状改善。该病例强调了帕金森病患者围手术期管理的重要性,包括及时补充药物和DBS功能,以预防神经抑制性恶性综合征(NMS)样并发症。麻醉师应警惕该人群中潜在的气道问题和NMS,并在手术期间保持最佳的液体状态。及时的干预可以防止不可逆的损伤并改善患者的预后。
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引用次数: 0
Actual Meal of Low Carbohydrate Diet (LCD) for Diabetic Patient Treated by Effective Imeglimin (Twymeeg) 低碳水化合物饮食(LCD)治疗糖尿病患者有效依米明(Twymeeg)
Pub Date : 2023-07-31 DOI: 10.36502/2023/asjbccr.6312
Tomoko Kusumoto, H. Bando, Kenji Hayashi, Eri Yasuoka, Michiaki Shibata, Hikaru Takagishi
The case is a 51-year-old male with obesity, type 2 diabetes (T2D), dyslipidemia, and hypertension. His HbA1c value increased to 8.0%, accompanied by oral semaglutide administration. Glucose variability was exacerbated after that, and then novel imeglimin (Twymeeg) was initiated. HbA1c decreased from 7.4% to 6.7% over 4 months with a 3 kg weight reduction. The case also had low back pain (LBP) and lumbar spinal stenosis (LSS), probably resulting from Metabolic syndrome (Met-S), and had actual experience with a low carbohydrate diet (LCD) in the hospital meals. Four patterns of LCD meals had carbohydrates ranging from 17.8g to 28.0g, with 501-690kcal.
该病例为51岁男性,患有肥胖症、2型糖尿病(T2D)、血脂异常和高血压。他的HbA1c值增加到8.0%,同时口服赛马鲁肽。在那之后,葡萄糖的变异性加剧,然后开始了新的依格列明(Twymeeg)。HbA1c在4个月内从7.4%下降到6.7%,体重减轻了3公斤。该病例还患有腰痛(LBP)和腰椎管狭窄症(LSS),可能是由代谢综合征(Met-S)引起的,并且在医院膳食中有低碳水化合物饮食(LCD)的实际经验。四种LCD膳食的碳水化合物含量从17.8克到28.0克不等,热量为501-690千卡。
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引用次数: 3
Bladder Spasm in Children after Surgery for Urethroplasty: A Case Report 儿童尿道成形术后膀胱痉挛1例报告
Pub Date : 2023-07-21 DOI: 10.36502/2023/asjbccr.6311
Yan Zeng, Jun Zeng
The incidence of bladder spasm in children with hypospadias treated with caudal block before surgery is uncommon. We presented a case of bladder spasm after urethroplasty surgery that was successfully treated with anisodamine without any sequelae. The caudal block plane may only reach the sacrum and does not reach the bladder wall. I suggest a local anesthetic drug dose of 1 ml/kg, totaling not more than 20 ml, to avoid the occurrence of postoperative bladder spasm and increase the comfort of children.
小儿尿道下裂术前行尾侧阻滞治疗,其膀胱痉挛的发生率并不多见。我们提出一个病例膀胱痉挛后尿道成形术成功治疗山莨菪碱没有任何后遗症。尾侧阻滞面可能只到达骶骨而不到达膀胱壁。我建议局麻药剂量为1ml /kg,总计不超过20ml,以避免术后膀胱痉挛的发生,增加患儿的舒适度。
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引用次数: 0
Catecholamine-Refractory Anaphylactic Shock to Vecuronium in a Patient with Tetralogy of Fallot: A Case Report 法洛四联症患者维库溴铵致儿茶酚胺难治性过敏性休克1例
Pub Date : 2023-07-03 DOI: 10.36502/2023/asjbccr.6310
Xinghui Xiong, Wei Wei
Serious anaphylactic reactions to anesthetics can be life-threatening events. Vecuronium is promoted as a neuromuscular blocking drug that is least likely to cause anaphylaxis due to its low histamine-releasing potential. Perioperative hypoxemia in patients with tetralogy of Fallot (TOF) due to anaphylactic reactions can be easily misdiagnosed as anoxic spells. We report a patient with TOF who suffered from symmetrical peripheral gangrene after undergoing catecholamine-refractory anaphylactic shock to vecuronium perioperatively. CPB (cardiopulmonary bypass) is the most effective support for severe anaphylactic shock during the perioperative period. Intradermal test screening for anaphylaxis to anesthetics is an effective method for prevention and diagnosis.
对麻醉剂的严重过敏反应可能危及生命。维库溴铵被认为是一种神经肌肉阻滞剂,由于其组胺释放潜力低,最不可能引起过敏反应。法洛四联症(TOF)患者因过敏反应引起的围手术期低氧血症很容易被误诊为缺氧期。我们报告了一名TOF患者,在围手术期接受儿茶酚胺难治性维库溴铵过敏性休克后,出现对称性外周坏疽。CPB(体外循环)是治疗围手术期严重过敏性休克最有效的支持方法。对麻醉剂过敏反应的皮内试验筛查是预防和诊断的有效方法。
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引用次数: 0
What Women Want: Real Time Results for Screening Mammography in the Era of Value-Based Care | A Single Institution Experience During the COVID-19 SARS-COV2 Pandemic 女性想要的:基于价值的护理时代乳房x光筛查的实时结果|在COVID-19 SARS-COV2大流行期间的单一机构体验
Pub Date : 2023-07-01 DOI: 10.36502/2023/asjbccr.6309
M. Kalambo, Toma S Omofoye, Ethan O. Cohen, J. Leung, T. Nghiem
Objective: Direct radiologist to patient communication has been linked to higher levels of patient satisfaction, compliance, and overall treatment outcomes. Recent studies examining patient expectations in breast imaging indicate that 90% of women prefer result communication and review of imaging directly from their radiologist. Though the primary components of diagnostic breast imaging are patient centered, supplemental data suggests that screening mammography result consultation may represent an additional opportunity for engagement in the new era of patient-experience driven care. The primary aim of our study was to examine patient preferences for receiving real time screening mammography result communication (RTRC) and characteristics that may influence their willingness to participate.Material and Methods: This quality-improvement based, IRB-approved, study was performed at three community-based academic breast radiology centers in a large metropolitan area between October 5, 2020, and January 2, 2021. Female patients presenting for screening mammography were invited to opt in for RTRC and/or participate in an electronic, HIPAA-compliant, simple survey that could be completed on the personal subject’s phone or tablet. Subjects opting in for RTRC were invited to wait in a consultation room during staff radiologist review. Once interpreted, the radiologist would discuss the results and next step recommendations with the patient. Self-reported patient demographic characteristics and RTRC preferences by age, race, ethnicity, level of education, household income, prior personal or family history of breast cancer, active (non-breast) cancer history and prior history of abnormal mammogram were assessed by categorical variable analysis using Chi-squared tests. A p-value <0.05 was determined to be statistically significant.Results: 1714 screening mammograms were performed across our three community-based breast imaging centers and 11% (186/1714) of women completed the survey during the study timeframe. White women (92%) were statistically more likely to opt in for RTRC when compared with non-white (80%) counterparts (p=.026). Patients with a personal history (p=0.001) or family history (p=0.006) of breast cancer were statistically more likely to opt in for RTRC when compared with other cohorts. A positive correlation was observed between prior history of abnormal mammogram and preference for receiving RTRC (93%) but did not achieve statistical significance (p=.082). There was no correlation observed between RTRC preference and an active (non-breast) cancer diagnosis (p=0.415).Conclusion: Our study confirms previous data suggesting that patients vastly prefer direct verbal communication ahead of written letter result notification. Our study also suggests that screening mammography RTRC may be of particular interest in patients with higher (personal or familial) risk for developing breast cancer. While this service may operationally add demand on ra
目的:放射科医生与患者的直接沟通与更高水平的患者满意度、依从性和整体治疗结果有关。最近对乳腺成像患者期望值的研究表明,90%的女性更喜欢直接从放射科医生那里进行结果沟通和成像审查。尽管乳腺诊断成像的主要组成部分是以患者为中心的,但补充数据表明,筛查乳房X光检查结果咨询可能代表着参与患者体验驱动护理新时代的额外机会。我们研究的主要目的是检查患者对接受实时筛查乳房X光检查结果沟通(RTRC)的偏好,以及可能影响他们参与意愿的特征。材料和方法:这项基于质量改进的、经IRB批准的研究于2020年10月5日至2021年1月2日在一个大城市地区的三个社区学术乳腺放射中心进行。受邀参加筛查乳房X光检查的女性患者可以选择参加RTRC和/或参加一项符合HIPAA的电子简单调查,该调查可以在个人受试者的手机或平板电脑上完成。选择RTRC的受试者被邀请在放射科医生审查期间在咨询室等待。一旦解释,放射科医生将与患者讨论结果和下一步建议。根据年龄、种族、民族、教育水平、家庭收入、既往乳腺癌症个人或家族史、活动(非乳腺)癌症史和既往异常乳房X光检查史,通过分类变量分析,使用Chi平方检验评估自报患者人口统计学特征和RTRC偏好。p值<0.05被确定为具有统计学意义。结果:在我们的三个社区乳腺成像中心进行了1714次筛查乳房X光检查,11%(186/1714)的女性在研究期间完成了调查。与非白人女性(80%)相比,白人女性(92%)选择RTRC的可能性更大(p=0.26)。与其他人群相比,有乳腺癌症个人病史(p=0.001)或家族史(p=0.006)的患者更可能选择RTRC。观察到乳房X光检查异常病史与接受RTRC的偏好之间存在正相关(93%),但没有达到统计学意义(p=.082)。RTRC偏好与活跃(非乳腺)癌症诊断之间没有相关性(p=0.415)。结论:我们的研究证实了先前的数据,表明患者非常喜欢直接言语交流在书面信函结果通知之前。我们的研究还表明,筛查乳腺摄影RTRC可能对癌症发展风险较高(个人或家庭)的患者特别感兴趣。虽然这项服务可能会在操作上增加对放射科医生患者面对面时间和护理成本的需求,但可以优先考虑可能在这项服务选项中找到价值的患者偏好和群体,以优化患者体验和临床工作流程。有必要进行更多的研究,以进一步验证哪些实践模式将从这种量身定制的服务中获得最大的好处。
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引用次数: 0
Anesthesia Management of a Patient with Papillary Thyroid Carcinoma Recurrence and Metastasis to the Right Atrium and Superior Vena Cava: A Case Report 1例甲状腺乳头状癌右心房及上腔复发转移患者的麻醉处理
Pub Date : 2023-06-27 DOI: 10.36502/2023/asjbccr.6308
X. Xiong
Postoperative recurrence and metastasis of papillary thyroid carcinoma (PTC) to the superior vena cava (SVC) and right atrium (RA) are rare. The application of Extracorporeal Jugular-femoral Vein Bypass and anesthesia management for SVC reconstruction in this rare situation holds instructive significance. In this case, we describe the successful anesthesia management of a patient with multiple tumor thrombi due to postoperative recurrence of PTC. The diagnosis was based on computed tomography of the chest and blood vessels, revealing three-dimensional SVC, postoperative recurrence of PTC, and multiple tumor thrombi in the internal jugular vein (IJV), subclavian vein, brachiocephalic vein, SVC, and RA. An experienced multidisciplinary team was established, and a detailed plan was made for respiration and circulation support, with cardiopulmonary bypass on standby.
甲状腺乳头状癌(PTC)术后向上腔静脉(SVC)和右心房(RA)的复发和转移是罕见的。在这种罕见的情况下,应用股颈静脉体外循环和麻醉管理进行SVC重建具有指导意义。在这种情况下,我们描述了一名因PTC术后复发而出现多发性肿瘤血栓的患者的成功麻醉管理。诊断基于胸部和血管的计算机断层扫描,显示三维SVC、PTC术后复发以及颈内静脉(IJV)、锁骨下静脉、头臂静脉、SVC和RA的多发性肿瘤血栓。成立了一支经验丰富的多学科团队,并制定了呼吸和循环支持的详细计划,心肺转流处于待命状态。
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引用次数: 0
Access and Utilization of Maternal Newborn and Child Health Services in the Fragile Context of Somalia 索马里脆弱地区母婴保健服务的获取和利用
Pub Date : 2023-06-26 DOI: 10.36502/2023/asjbccr.6307
V. Onama, Geoffrey Babughirana
Background: The humanitarian situation in Somalia is characterized by unstable government, insecurity, fragility, and limited investments in funding essential public services and maternal newborn and health services are not spared. The health system in Somalia remained under-resourced to meet the urgent lifesaving, essential, and preventive health services. This study sought to assess the access and utilization of maternal and newborn child health services in Somalia.Methodology: A cross-sectional design was used in this study. Descriptive and inferential statistical data analysis was conducted to establish the performance of indicators and relationships. The study targeted mothers of children 0-59 months.Results: The results show a low (13.1%) attendance of focused (4th visit) antenatal care among the mothers. 23.3% of the mothers from Somaliland attended at least three antenatal care visits, while the rest of the states only achieved less than 10%. At least 41.5% of the deliveries occurred at the health facility. Skilled attendants assisted 42.7% of the deliveries. No significant difference was observed in the number of women having an extra meal during pregnancy or delivery at the health facility or in predicting the number of ANC visits. Nonetheless, 43.2% of the infants in Somalia had not been exclusively breastfed for the first six months of life. The results equally demonstrated poor nutritional index with only 38.4% of the pregnant women having an extra meal during pregnancy. In Somalia, early health care seeking for common childhood illnesses is still low, with Respiratory Tract infections (RTIs) at 40%, malaria at 56.6%, and diarrhea at 63.4%.Conclusion and Recommendations: There is a need for deliberate efforts to improve low-performing indicators and hence improve the survival of mothers and children.
背景:索马里的人道主义局势的特点是政府不稳定、不安全、脆弱,在资助基本公共服务和母婴保健服务方面的投资有限。索马里的卫生系统在满足紧急救生、基本和预防性卫生服务方面仍然资源不足。本研究旨在评估索马里孕产妇和新生儿保健服务的获取和利用情况。方法:本研究采用横断面设计。进行描述性和推断性统计数据分析,以建立绩效指标和关系。这项研究的对象是0-59个月大孩子的母亲。结果:结果显示,在母亲中,重点(第四次就诊)产前护理的出勤率较低(13.1%)。来自索马里兰的23.3%的母亲至少接受了三次产前检查,而其他州只接受了不到10%的产前检查。至少41.5%的分娩发生在卫生机构。熟练的服务员协助了42.7%的分娩。在怀孕或分娩期间在卫生机构多吃一顿饭的女性人数或ANC就诊次数的预测方面没有观察到显著差异。尽管如此,在索马里,43.2%的婴儿在生命的前六个月没有完全母乳喂养。结果同样表明营养指数较差,只有38.4%的孕妇在怀孕期间多吃了一顿饭。在索马里,儿童常见疾病的早期医疗保健需求仍然很低,呼吸道感染占40%,疟疾占56.6%,腹泻占63.4%。结论和建议:需要有意识地努力改善低绩效指标,从而提高母亲和儿童的生存率。
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引用次数: 0
Stroke Secondary to Fibromuscular Dysplasia 继发于纤维肌发育不良的中风
Pub Date : 2023-06-26 DOI: 10.36502/2023/asjbccr.6306
Ashwin Sidhu, Harrison Chu
FMD is a rare systemic vascular disease characterized by abnormal cell proliferation in the artery walls, leading to artery narrowing, twisting, or bulging. It commonly affects the carotid and renal arteries and can result in renal diseases and stroke. This paper presents a case study of a 39-year-old unhoused female patient who experienced a stroke secondary to fibromuscular dysplasia (FMD) and left ventricular thrombus. The patient presented with asymmetric movement of the extremities and psychosis, so intoxication was initially suspected. However, further examination revealed facial asymmetry and motor weakness. CT scans showed a left anterior cerebral artery infarction and irregular contour of the cervical internal carotid arteries, consistent with FMD and carotid thrombus. Management involved stabilizing the patient, providing supportive treatment, and controlling blood pressure. Thrombolytic therapy was not administered due to the time elapsed since symptom onset. The patient was started on anticoagulation for the carotid plaque and left ventricular thrombus. A transthoracic echocardiogram revealed a large left ventricular thrombus and left atrial enlargement, and the patient was started on heart failure medications.FMD and left ventricular thrombus are not directly related, but FMD can contribute to thrombus development through its impact on the cardiovascular system, including hypertension, arterial wall damage, aneurysm development, or dissection. Treatment for FMD may involve medication, observation, or surgical interventions like angioplasty and stenting. Anticoagulation therapy is essential for managing the left ventricular thrombus.This case highlights the importance of early diagnosis and treatment of FMD to prevent complications such as stroke. It is important to consider FMD in the diagnosis of younger patients with a stroke, especially those with a history of hypertension, substance abuse, or other risk factors. Further research is needed to better understand the relationship between FMD and stroke and to optimize treatment strategies for these patients.
FMD是一种罕见的全身性血管疾病,其特征是动脉壁细胞异常增殖,导致动脉狭窄、扭曲或膨出。它通常影响颈动脉和肾动脉,并可能导致肾脏疾病和中风。本文介绍了一例39岁未使用的女性患者的病例研究,该患者经历了继发于纤维肌发育不良(FMD)和左心室血栓的中风。患者表现为四肢不对称运动和精神病,因此最初怀疑是中毒。然而,进一步检查发现面部不对称和运动无力。CT扫描显示左前大脑动脉梗死,颈颈内动脉轮廓不规则,与FMD和颈动脉血栓一致。管理包括稳定患者、提供支持性治疗和控制血压。由于症状出现后经过了一段时间,因此未进行溶栓治疗。患者开始接受颈动脉斑块和左心室血栓的抗凝治疗。经胸超声心动图显示有大的左心室血栓和左心房扩大,患者开始服用心力衰竭药物。FMD和左心室血栓没有直接关系,但FMD可以通过对心血管系统的影响促进血栓的发展,包括高血压、动脉壁损伤、动脉瘤发展或夹层。FMD的治疗可能包括药物治疗、观察或手术干预,如血管成形术和支架植入术。抗凝治疗对于治疗左心室血栓至关重要。该病例强调了FMD早期诊断和治疗对预防中风等并发症的重要性。在诊断年轻的中风患者时,尤其是那些有高血压、药物滥用或其他危险因素病史的患者时,考虑FMD是很重要的。需要进一步的研究来更好地了解FMD与中风之间的关系,并优化这些患者的治疗策略。
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引用次数: 0
Maintained Renal Function by Blood Pressure Control in Patient with Diabetic Kidney Disease (DKD) 通过控制血压维持糖尿病肾病患者的肾功能
Pub Date : 2023-06-24 DOI: 10.36502/2023/asjbccr.6305
H. Bando, Noboru Iwatsuki, M. Okada, T. Ogawa, K. Sakamoto
The case involves a 74-year-old male with type 2 diabetes (T2D), hypertension, dyslipidemia, and diabetic kidney disease (DKD) at nephropathy stage G3b. He has been receiving treatment with insulin and anti-hypertensive agents (AHAs). In July 2021, his HbA1c was elevated to 7.9%. As a result, the extent of his low carbohydrate diet (LCD) was increased, and insulin doses were raised. The AHAs were changed from Olmesartan to Valsartan/Amlodipine, and Irbesartan/Amlodipine until 2023. By January 2023, his HbA1c had decreased to 6.8%, and his eGFR (CKD-EPI) had remained stable at 34-48 mL/min/1.73/m2 for 4 years. A recent study demonstrated clinical improvement in renal function through continuous LCD in patients with DKD.
该病例涉及一名74岁男性,患有2型糖尿病(T2D)、高血压、血脂异常和肾病G3b期糖尿病肾病(DKD)。他一直在接受胰岛素和抗高血压药物(AHA)的治疗。2021年7月,他的HbA1c升高至7.9%。因此,他的低碳水化合物饮食(LCD)范围增加,胰岛素剂量增加。AHA从奥美沙坦改为缬沙坦/氨氯地平,并在2023年前改为厄贝沙坦/氨氯地平。到2023年1月,他的HbA1c已降至6.8%,他的eGFR(CKD-EPI)在4年内稳定在34-48 mL/min/1.73/m2。最近的一项研究表明,DKD患者通过连续液晶显示可改善肾功能。
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引用次数: 0
Anesthetic Management of an Unusual Case of Severe Pulmonary Hypertensive 一例罕见严重肺动脉高压的麻醉处理
Pub Date : 2023-06-13 DOI: 10.36502/2023/asjbccr.6304
P. Sun
The perioperative management of pulmonary hypertension continues to be a great challenge for anesthesiologists. Among the various types of pulmonary hypertension, pulmonary hypertension associated with left heart disease is the most common, while pulmonary hypertensive crisis is one of the causes of perioperative mortality in these patients. We present the case of a 54-year-old female with severe valvular heart disease complicated by severe pulmonary hypertension and massive hemothorax, who underwent emergency exploratory thoracotomy, mitral valve replacement, and tricuspid valvuloplasty. The patient was in critical condition and suspected to have a pulmonary hypertension crisis. The rationale for this case report is to learn about the anesthetic management of patients with severe pulmonary hypertension.
肺动脉高压的围手术期管理仍然是麻醉师面临的巨大挑战。在各种类型的肺动脉高压中,与左心相关的肺动脉高血压最为常见,而肺动脉高压危象是这些患者围手术期死亡的原因之一。我们报告一例54岁女性,患有严重瓣膜性心脏病,并发严重肺动脉高压和大量血胸,她接受了紧急开胸探查术、二尖瓣置换术和三尖瓣成形术。患者情况危急,怀疑有肺动脉高压危象。本病例报告的基本原理是了解严重肺动脉高压患者的麻醉管理。
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引用次数: 0
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Asploro journal of biomedical and clinical case reports
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