Pub Date : 2023-01-01DOI: 10.29254/2523-4110-2023-2-169/addition-53-55
Олена Анатоліївна Кир’ян, А. Е. Дорофєєв, М. Ю. Бабаніна, Юлія Олексіївна Іщейкіна, Григорій Вілійович Волченко, Ігор Валерійович Іваницький, Володимир Григорович Лебідь
{"title":"СУЧАСНИЙ ПІДХІД ДО ФОРМУВАННЯ ЕКОЛОГІЧНОЇ КОМПЕТЕНТНОСТІ ЛІКАРЯ-ІНТЕРНА ЗАГАЛЬНОЇ ПРАКТИКИ ТА СІМЕЙНОЇ МЕДИЦИНИ","authors":"Олена Анатоліївна Кир’ян, А. Е. Дорофєєв, М. Ю. Бабаніна, Юлія Олексіївна Іщейкіна, Григорій Вілійович Волченко, Ігор Валерійович Іваницький, Володимир Григорович Лебідь","doi":"10.29254/2523-4110-2023-2-169/addition-53-55","DOIUrl":"https://doi.org/10.29254/2523-4110-2023-2-169/addition-53-55","url":null,"abstract":"","PeriodicalId":9360,"journal":{"name":"Bulletin of Problems Biology and Medicine","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72792408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.29254/2523-4110-2023-2-169/addition-8-9
Ya. O. Oliinichenko, S. Bilash
The obtained results were analysed on a computer using the «InStat» application program package. The difference was considered probable at values of p<0.05.
所得结果在计算机上使用«InStat»应用程序包进行分析。当p<0.05时，认为差异可能存在。
{"title":"MORPHOLOGICAL CHARACTERISTICS OF THE WALL OF RATS' ILEUM WHEN USING A FOOD ADDITIVES COMPLEX","authors":"Ya. O. Oliinichenko, S. Bilash","doi":"10.29254/2523-4110-2023-2-169/addition-8-9","DOIUrl":"https://doi.org/10.29254/2523-4110-2023-2-169/addition-8-9","url":null,"abstract":"The obtained results were analysed on a computer using the «InStat» application program package. The difference was considered probable at values of p<0.05.","PeriodicalId":9360,"journal":{"name":"Bulletin of Problems Biology and Medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73412651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.29254/2523-4110-2023-2-169/addition-11
М.А. Л. Василів, З. З. Масна
{"title":"ВАРІАБЕЛЬНІСТЬ ЛІНІЙНИХ РОЗМІРІВ ЛОБНИХ ПАЗУХ У ЧОЛОВІКІВ ЗРІЛОГО ВІКУ","authors":"М.А. Л. Василів, З. З. Масна","doi":"10.29254/2523-4110-2023-2-169/addition-11","DOIUrl":"https://doi.org/10.29254/2523-4110-2023-2-169/addition-11","url":null,"abstract":"","PeriodicalId":9360,"journal":{"name":"Bulletin of Problems Biology and Medicine","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73767501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.29254/2523-4110-2023-2-169/addition-16
А. М. Скоробогатов, Вікторія Пастухова, Г. В. Лук’янцева, С. П. Краснова, Т. М. Олійник, Войцех Сосновський, С. М. Дубинська
{"title":"ВІКОВІ ОСОБЛИВОСТІ МОРФОГЕНЕЗУ СКЕЛЕТНИХ ТКАНИН НА ТЛІ ВПЛИВУ ЕПІХЛОРГІДРИНУ","authors":"А. М. Скоробогатов, Вікторія Пастухова, Г. В. Лук’янцева, С. П. Краснова, Т. М. Олійник, Войцех Сосновський, С. М. Дубинська","doi":"10.29254/2523-4110-2023-2-169/addition-16","DOIUrl":"https://doi.org/10.29254/2523-4110-2023-2-169/addition-16","url":null,"abstract":"","PeriodicalId":9360,"journal":{"name":"Bulletin of Problems Biology and Medicine","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79082792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.29254/2077-4214-2023-1-168-92-96
V. Shatorna, I. I. Kononova, V. Garets, O. Nefodova, L. L. Lomyha
{"title":"SEARCH OF NEW BIOANTAGONISTS OF EMBRYOTOXICITY OF CADMIUM CHLORIDE IN A CHRONIC EXPERIMENT ON RATS","authors":"V. Shatorna, I. I. Kononova, V. Garets, O. Nefodova, L. L. Lomyha","doi":"10.29254/2077-4214-2023-1-168-92-96","DOIUrl":"https://doi.org/10.29254/2077-4214-2023-1-168-92-96","url":null,"abstract":"","PeriodicalId":9360,"journal":{"name":"Bulletin of Problems Biology and Medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81534274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.29254/2077-4214-2023-2-169-478-482
S. S. Tkachenko, O. G. Rodinsky
t-test). Changes in indi - cators were considered probable at p<0.05 [6]. The aim of the research was to find out the effect of long term androgen deficiency on skeletal muscles and neuromuscular synapse by bioelectrical activity studying. A 4-month hypoandrogenic state model was created by bilateral orchiectomy on sexually mature male Wistar rats. The parameters of the excitability, evoked potentials of the skeletal muscle and functional mobility of the neuromuscular synapse were studied. As a result, after 4 months of a hypoandrogenic state, the threshold of the neuromuscular apparatus excitation increased, especially with indirect irritation (up to 300%). The latency and duration of the evoked response, as well as the amplitude of the muscle action potential, were increased. A lengthening of the refractory period manifested itself in the slowing down of the response amplitude recovery to the test stimulus in the experimental group when stimulation with double pulses was used. During stimulation by series of impulses with a frequency more than 200 Hz, a rhythm transformation was observed in castrated animals, while in the control group the synapse was able to transmit a signal with a frequency up to 400 Hz. Thus, negative functional changes in the neuromuscular complex in conditions of long-term hypoandrogenemia can be explained mostly by bioelectrical changes of nervous structures of the neuromotor unit, namely, sharp decrease excitability, deterioration of the amplitude-time characteristics of the action potential and a decrease in the functional stability of the synaptic connection.
{"title":"ELECTROPHYSIOLOGICAL STUDY OF THE LONG-TERM HYPOANDROGENISM EFFECT ON THE NEUROMUSCULAR APPARATUS","authors":"S. S. Tkachenko, O. G. Rodinsky","doi":"10.29254/2077-4214-2023-2-169-478-482","DOIUrl":"https://doi.org/10.29254/2077-4214-2023-2-169-478-482","url":null,"abstract":"t-test). Changes in indi - cators were considered probable at p<0.05 [6]. The aim of the research was to find out the effect of long term androgen deficiency on skeletal muscles and neuromuscular synapse by bioelectrical activity studying. A 4-month hypoandrogenic state model was created by bilateral orchiectomy on sexually mature male Wistar rats. The parameters of the excitability, evoked potentials of the skeletal muscle and functional mobility of the neuromuscular synapse were studied. As a result, after 4 months of a hypoandrogenic state, the threshold of the neuromuscular apparatus excitation increased, especially with indirect irritation (up to 300%). The latency and duration of the evoked response, as well as the amplitude of the muscle action potential, were increased. A lengthening of the refractory period manifested itself in the slowing down of the response amplitude recovery to the test stimulus in the experimental group when stimulation with double pulses was used. During stimulation by series of impulses with a frequency more than 200 Hz, a rhythm transformation was observed in castrated animals, while in the control group the synapse was able to transmit a signal with a frequency up to 400 Hz. Thus, negative functional changes in the neuromuscular complex in conditions of long-term hypoandrogenemia can be explained mostly by bioelectrical changes of nervous structures of the neuromotor unit, namely, sharp decrease excitability, deterioration of the amplitude-time characteristics of the action potential and a decrease in the functional stability of the synaptic connection.","PeriodicalId":9360,"journal":{"name":"Bulletin of Problems Biology and Medicine","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85886466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.29254/2077-4214-2023-1-168-187-199
T. Kolesnyk, O. Fursa
{"title":"CHANGES IN THE STRUCTURAL AND FUNCTIONAL STATUS OF THE LEFT VENTRICLE IN PATIENTS WITH ARTERIAL HYPERTENSION WHO HAVE UNDERGONE MYOCARDIAL INFARCTION","authors":"T. Kolesnyk, O. Fursa","doi":"10.29254/2077-4214-2023-1-168-187-199","DOIUrl":"https://doi.org/10.29254/2077-4214-2023-1-168-187-199","url":null,"abstract":"","PeriodicalId":9360,"journal":{"name":"Bulletin of Problems Biology and Medicine","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88948501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.29254/2077-4214-2022-4-167-269-280
Y. Solovey, V. Polevoy, M. Solovey
{"title":"THE USE OF VECTOR – PARAMETRIC FLUORESCENCE POLARIZATION MICROSCOPY OF HISTOLOGICAL SECTIONS OF SPLEEN OF RATS WITH ABDOMINAL SEPSIS IN EXPERIMENT","authors":"Y. Solovey, V. Polevoy, M. Solovey","doi":"10.29254/2077-4214-2022-4-167-269-280","DOIUrl":"https://doi.org/10.29254/2077-4214-2022-4-167-269-280","url":null,"abstract":"","PeriodicalId":9360,"journal":{"name":"Bulletin of Problems Biology and Medicine","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90549436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.29254/2077-4214-2022-4-167-322-325
D. Dychko, O. Dychko, O. Nekhanevych, V. Sheiko, O. Klymenko, V. Yakovenko, V. Dychko
{"title":"THE CELL REACTIVITY OF THE BODY OF CHILDREN WITH SCOLIOSIS","authors":"D. Dychko, O. Dychko, O. Nekhanevych, V. Sheiko, O. Klymenko, V. Yakovenko, V. Dychko","doi":"10.29254/2077-4214-2022-4-167-322-325","DOIUrl":"https://doi.org/10.29254/2077-4214-2022-4-167-322-325","url":null,"abstract":"","PeriodicalId":9360,"journal":{"name":"Bulletin of Problems Biology and Medicine","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86073960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.29254/2523-4110-2023-2-169/addition-67-68
З. М. Небесна, О. П. Андріїшин, І. Б. Гетманюк, С. Б. Крамар, Н. В. Огінська, А. В. Довбуш, С. О. Литвинюк
{"title":"НАМ УЖЕ 50, АЛЕ НАМ ЛИШЕ 50","authors":"З. М. Небесна, О. П. Андріїшин, І. Б. Гетманюк, С. Б. Крамар, Н. В. Огінська, А. В. Довбуш, С. О. Литвинюк","doi":"10.29254/2523-4110-2023-2-169/addition-67-68","DOIUrl":"https://doi.org/10.29254/2523-4110-2023-2-169/addition-67-68","url":null,"abstract":"","PeriodicalId":9360,"journal":{"name":"Bulletin of Problems Biology and Medicine","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88740317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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