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A cross-sectional study to assess the risk factors for the presence and severity of obstructive sleep apnea among patients with type 2 diabetes mellitus at a tertiary care hospital, Gangtok 一项横断面研究,评估在Gangtok三级医院的2型糖尿病患者中阻塞性睡眠呼吸暂停的存在和严重程度的危险因素
Divija Sharma, B. Khandelwal, S. Kar
Background and Objectives: Diabetes mellitus (T2DM) and obstructive sleep apnea (OSA) are common disorders that not only often coexist but also have a bidirectional association where each condition exacerbates the other. The present study was performed to ascertain the occurrence and predictors of risk factors of OSA in patients with type 2DM. Materials and Methods: A cross-sectional hospital-based study recruiting 164 patients for over 2 months was conducted, in which each diabetic patient was assigned to complete a questionnaire on various variables followed by a general physical examination for associated comorbidities diabetic complications (neuropathy, nephropathy, and retinopathy). Their fasting blood glucose (FBG) and hemoglobin A1c (HbA1c) levels were recorded, following which they were administered and assessed using Berlin Questionnaire and Epworth Sleepiness Score for risk category and daytime sleepiness. Patients with already diagnosed OSA including ones receiving treatment for it were excluded from the study. Results: Of the 164 diabetic patients recruited in the study, 64 (39%) were at high risk for OSA in contrast to the 100 (61%) who were at low risk for OSA. Neck circumference, waist circumference, presence of hypertension and more than one comorbidities along with patients who experienced witnessed apnea at least three times a week, excessive daytime sleepiness, and habitual snorers found to be significant risk factors and practices in posing DM patients at a higher risk for OSA. Patients with body mass index ≥25 were more likely to have a high risk of OSA. FBG and HbA1c were not significant risk factors for OSA. Conclusions: OSA has a high prevalence in subjects with T2DM which reinforces the clinicians to remain observant for signs and symptoms of OSA in diabetic patients and monitor their compliance in terms of weight management, diet control, and medication adherence.
背景和目的:糖尿病(T2DM)和阻塞性睡眠呼吸暂停(OSA)是常见的疾病,不仅经常共存,而且具有双向关联,每一种情况都加剧了另一种情况。本研究旨在确定2型糖尿病患者OSA的发生及危险因素的预测因素。材料与方法:一项以医院为基础的横断面研究,招募了164例患者,为期2个多月。在该研究中,每位糖尿病患者被分配完成一份关于各种变量的问卷,随后进行了相关合并症糖尿病并发症(神经病变、肾病和视网膜病变)的一般体格检查。记录他们的空腹血糖(FBG)和血红蛋白A1c (HbA1c)水平,然后使用柏林问卷和爱普沃斯嗜睡评分对他们的风险类别和白天嗜睡进行管理和评估。已经诊断为阻塞性睡眠呼吸暂停的患者以及正在接受治疗的患者被排除在研究之外。结果:在研究中招募的164名糖尿病患者中,64名(39%)处于OSA的高风险,而100名(61%)处于OSA的低风险。颈围、腰围、高血压和一种以上合并症的存在以及每周至少三次见证呼吸暂停的患者、白天过度嗜睡和习惯性打鼾被发现是DM患者患OSA风险较高的重要危险因素和做法。体重指数≥25的患者发生OSA的风险较高。FBG和HbA1c不是OSA的显著危险因素。结论:OSA在T2DM患者中有很高的患病率,这加强了临床医生对糖尿病患者的OSA症状和体征的观察,并监测他们在体重管理、饮食控制和药物依从性方面的依从性。
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引用次数: 0
A cross-sectional study on research practices among doctors in India 印度医生研究实践的横断面研究
A. Rathi, Vikas Kumar, J. Majhi, N. Jayaraj, Satyavir Singh
Introduction: When doctors assume the role of a researcher, then they have to play from both ends – many times, the enthusiasm of research might play with morality of a physician. The quality of research in India is not at par with most countries and it has a publication share of only 1.59%. Objectives: The objectives were to find out the research practices of doctors to identify loopholes in research and recommend rectifications. Materials and Methods: It is a cross-sectional study done with the help of an anonymous online pretested questionnaire. The questionnaire was randomly mailed from a mailing list to 500 doctors of different places and specialties and 100 of them filled the form and participated in the study. Results: Out of the 100 participants, 77 (77%) said that they had received some training or have attended some workshop on research methodology. More than one-fourth of the researchers agreed to modifying data to get desired results and 14% agreed to producing false data owing to the pressure by a supervisor. Almost one-third of the researchers agreed to having deliberately ignored bias or errors in their studies. Twenty-three percent revealed that they do not always take informed consent from their study subjects. More than one-third researchers revealed that they do not seek the permission of the institutional ethics committee (IEC) before commencing a study. The proportion of researchers having low, medium, or high good research practices score is 15.4%, 21.8%, and 62.8%, respectively. Conclusion: Majority of researchers indulge in misconduct, knowing, and unknowingly. These issues need to be tackled through capacity building, training of investigators and IEC members, strengthening of IEC functioning, and encouraging greater community participation.
引言:当医生扮演研究者的角色时,他们就必须从两端发挥作用——很多时候,研究的热情可能会与医生的道德一起发挥作用。印度的研究质量与大多数国家不一样,它的出版份额只有1.59%。目的:了解医生的研究实践,发现研究漏洞,提出整改建议。材料和方法:这是一项横断面研究,通过匿名在线预测问卷完成。问卷从邮寄列表中随机邮寄给500名不同地区、不同专业的医生,其中100人填写问卷并参与研究。结果:在100名受访者中,77人(77%)表示曾接受有关研究方法的培训或参加工作坊。超过四分之一的研究人员同意修改数据以获得期望的结果,14%的研究人员同意由于主管的压力而产生虚假数据。几乎三分之一的研究人员同意在他们的研究中故意忽略偏见或错误。23%的人透露,他们并不总是征求研究对象的知情同意。超过三分之一的研究人员透露,他们在开始一项研究之前没有征求机构伦理委员会(IEC)的许可。良好研究实践得分低、中、高的比例分别为15.4%、21.8%和62.8%。结论:大多数研究人员在知情和不知情的情况下沉迷于不当行为。这些问题需要通过能力建设、培训调查人员和独立选举委员会成员、加强独立选举委员会的职能以及鼓励更多的社区参与来解决。
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引用次数: 0
Satisfaction among COVID-19 positive patients: A study in a tertiary care hospital in central India COVID-19阳性患者的满意度:印度中部一家三级保健医院的研究
Arvind Sharma, Deepali Soni, P. Dubey, Richa Sharma, Aditi Bharti, T. Singh
Background: In the scenario of the COVID-19 pandemic, it is important to assess the quality of care that is being provided to COVID-19 positive patients as the health-care quality plays a crucial role in winning over any health crisis. Objective: This study aims to assess satisfaction among COVID-19 positive patients in a tertiary care hospital. Methodology: A retrospective cross-sectional study was done on COVID-19 positive patients admitted in a tertiary hospital of central India. Sample size was calculated by using the following formula: n = Z2 pq/d2, which came out to be 113. Simple random sampling was done to select the patients. A quantitative structured interview schedule was used to collect data. Results: Majority of the respondents were satisfied with the available amenities, clinical care, and behavior of health-care providers except services regarding linen, toilet, and doctors' explanation of illness and treatment. Overall impression of the visit was excellent to good according to 84% of the respondents. On inquiring the likelihood of recommending this hospital to others, 91.3% of the respondents gave a positive reply. Conclusion: Improvement is needed in linen and toilet facilities. Patients should be counseled via telephones regarding their illness and treatment if this is not possible face to face as the treating physicians are in personal protective equipment kits and it is quite difficult to interact while wearing these kits. Patient satisfaction surveys should be institutionalized periodically.
背景:在COVID-19大流行的情况下,评估向COVID-19阳性患者提供的护理质量非常重要,因为卫生保健质量在战胜任何健康危机方面发挥着至关重要的作用。目的:评价某三级医院新冠肺炎阳性患者的满意度。方法:对印度中部一家三级医院收治的COVID-19阳性患者进行回顾性横断面研究。样本量的计算公式为:n = Z2 pq/d2,结果为113。采用简单随机抽样的方法选择患者。采用定量结构化访谈表收集数据。结果:除了床单、厕所和医生的疾病解释和治疗外,大多数受访者对现有的设施、临床护理和卫生保健提供者的行为感到满意。84%的受访者认为是次参观的整体印象极好至好。对于向他人推荐该医院的可能性的提问,91.3%的回答者给出了肯定的回答。结论:医院的布草和卫生间设施有待改进。如果不可能面对面咨询患者的病情和治疗情况,则应通过电话咨询患者,因为治疗医生都有个人防护装备包,而且戴着这些装备包很难与患者互动。患者满意度调查应定期制度化。
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引用次数: 4
“Texting neck” or “iNeck pain” syndrome – An emerging public health threat: In the era of NEW NORMAL “短信脖”或“脖子痛”综合症——新常态时代的公共健康威胁
Sudip Bhattacharya, S. Saleem, R. Juyal, R. Kaur, Amarjeet Singh
“Texting neck” or “iNeck pain” syndrome is emerging as a public health threat globally because of our adjustment to a NEW NORMAL existence (work-from-home culture) because of the COVID-19 pandemic. This term coined by Dr. Dean L. Fishman, “text neck,” refers to overuse syndrome or a repetitive stress injury, in which we have our head hung forward and down looking at our cellular electronic device for prolonged durations. In our normal anatomical position, neck muscle groups are designed to endure the load of our head, which is about 10–12 pounds and when we bend our head ahead for an inch, we double the weight on these neck muscle groups. The signs and symptoms vary from continual nagging ache to muscle fatigue and limited variety of neck movements. For handling “Texting neck” or “iNeck ache” syndrome, nonpharmacological and pharmacological treatment alternatives are available. The burden of neck pain is already high in countries such as Norway, Finland, and Denmark. It is emerging as a public health problem in other countries also, thanks to work-from-home culture in the COVID-19 era. Few studies have revealed that the awareness for texting neck is poor among poor countries, and increasing population awareness about the risk factors and preventive measures for neck pain is the only way to tackle this emerging threat.
“短信脖”或“颈部疼痛”综合征正在成为全球公共卫生威胁,因为我们正在适应新常态(在家工作文化)。迪安·l·菲什曼(Dean L. Fishman)博士创造的“短信脖”一词,指的是过度使用综合症或重复性应激性损伤,这种情况下,我们的头一直向前或向下垂着,长时间盯着手机。在我们正常的解剖位置,颈部肌肉群被设计来承受我们头部的负荷,大约是10-12磅,当我们向前弯曲一英寸时,颈部肌肉群的重量就会增加一倍。体征和症状各不相同,从持续的唠叨疼痛到肌肉疲劳和颈部活动有限。对于“短信脖”或“颈痛”综合症,有非药物和药物治疗方案可供选择。在挪威、芬兰和丹麦等国家,颈部疼痛的负担已经很高了。在其他国家,由于新冠肺炎时代的在家工作文化,这也成为了一个公共卫生问题。很少有研究表明,贫穷国家对短信脖的认识很差,提高人们对风险因素和预防颈部疼痛措施的认识是解决这一新兴威胁的唯一途径。
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引用次数: 2
COVID-19 vaccine: A battle with the uncertainties and infodemics COVID-19疫苗:与不确定性和信息流行病作斗争
Sudip Bhattacharya, S. Saleem, Amarjeet Singh
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引用次数: 1
A cross-sectional survey of iodine deficiency disorders among school children (aged: 6–12 years) in Kashmir valley, Northern India 印度北部克什米尔谷地学龄儿童(6-12岁)碘缺乏症横断面调查
Sheikh Saleem, S. Khan, I. Haq, M. Qurieshi
Objectives of the Study: The objectives of the present study which was conducted in four districts of Kashmir valley (Anantnag, Baramulla, Budgam, and Srinagar) were to (1) estimate the “total goitre rate” (TGR) among schoolchildren in the age group of 6–12 years, (2) estimate the proportion of households with adequately iodized salt, and (3) to assess the dietary iodine intake by measuring urinary iodine levels. Study Design: Prospective, cross-sectional study. Methodology: The present study was conducted in the four districts of Kashmir Valley, namely Anantnag, Baramulla, Budgam, and Srinagar in March 2017. This was a school-based study among children in the age group of 6–12 years. For each district, 30 schools were randomly selected using Probability Proportionate to Size sampling. A total of 90 students (45 boys and 45 girls) were randomly selected from each school. Selected children were examined by trained doctors for the presence of goitre. Every 5th child in the school was selected for the collection of the salt sample from the child's house. Every 10th child in the school was selected for the collection of the urine sample for iodine estimation. Results: A total of 10,800 children in the age group of 6–12 years were examined in the four districts. The overall TGR for the four districts combined was 14.8%. The TGR was the highest in district Budgam (16.4%) and lowest in district Anantnag (13.8%). Across all districts, ≤1% of the examined children had a goitre of Grade II. In districts Baramulla, Budgam, and Srinagar, an increasing trend in TGR was observed with age. The median urinary iodine ranged from a minimum of 46.14 μg/L in district Baramulla to a maximum of 56.06 μg/L in district Anantnag. Conclusion: The TGR was high in all the four districts, way beyond the 10% iodine deficiency disorder control goal that was to be achieved by the year 2012. Moreover, the population level median urinary iodine was less than the recommended ≥100 μg/L in all the four districts. Except for district Anantnag, all three districts had median urinary iodine levels of <50 μg/L indicating moderate iodine deficiency.
研究目的:本研究在克什米尔山谷的四个地区(Anantnag、Baramulla、Budgam和Srinagar)进行,目的是:(1)估计6-12岁学龄儿童的“总甲状腺肿率”(TGR),(2)估计有充足碘盐的家庭比例,(3)通过测量尿碘水平来评估膳食碘摄入量。研究设计:前瞻性横断面研究。方法:本研究于2017年3月在克什米尔山谷的四个地区进行,即Anantnag, Baramulla, Budgam和Srinagar。这是一项以学校为基础的研究,对象是6-12岁的儿童。每个地区随机选择30所学校,采用概率与规模成比例的抽样方法。从每所学校随机抽取90名学生(45名男生和45名女生)。选定的儿童由训练有素的医生检查是否有甲状腺肿。学校中每5个孩子中就有一个被选中从孩子的家里收集盐样本。每10名儿童中抽取1名儿童尿样进行碘测定。结果:共对4区6 ~ 12岁儿童10800名进行了调查。这四个地区的总体TGR加起来为14.8%。其中,Budgam区最高(16.4%),Anantnag区最低(13.8%)。在所有地区,≤1%的接受检查的儿童患有II级甲状腺肿。在巴拉穆拉、布德加姆和斯利那加地区,TGR随年龄增长呈上升趋势。尿碘中位数从巴拉穆拉区最低46.14 μg/L到阿南南格区最高56.06 μg/L不等。结论:4个地区的碘缺乏症发病率均较高,远未达到2012年控制碘缺乏症10%的目标。人群尿碘水平中位数均低于推荐值≥100 μg/L。除Anantnag区外,其余3个区尿碘中位数均<50 μg/L,提示中度缺碘。
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引用次数: 0
COVID-19 central sampling team: An experience from AIIMS, New Delhi COVID-19中央抽样小组:来自新德里AIIMS的经验
R. Reddy, Arvind Kumar, Komal Singh, N. Wig
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引用次数: 0
Landolfi's Sign: A Riddle for Primary Care Physicians. 兰多菲氏症:初级保健医生的一个难题。
Pub Date : 2020-09-01 Epub Date: 2020-12-31 DOI: 10.4103/jopcs.jopcs_14_20
Ritwik Ghosh, Swagatam Sengupta, Sk Minhajuddin Siraj, Julián Benito-León

Landolfi's sign, alternating systolic constriction and diastolic dilatation of pupils, is a clinical hallmark of aortic regurgitation. It is thought to stem from exacerbation of physiological circulatory hippus in the vessels of iris due to a wide pulse pressure in a backdrop of severe aortic valvular incompetence. Degenerative and rheumatic heart diseases are exquisitely common in rural India and often these patients turn up late with complications to the primary care physicians. Herein, the authors report a 34-year-old pregnant female who presented with acute heart failure, and on examination, Landolfi's sign was found. It was immediately followed by Doppler echocardiography to stamp it as a case of severe aortic regurgitation. The patient was stabilized with anti-failure medications and feto-maternal health was closely monitored. The authors want to conclude claiming that bedside clinical training in cardiology will forever remain important, more so, while dealing patients at non-sophisticated primary health-care facilities. Besides, they also argue that basic tool supports like an echocardiography should be made available at those centers.

兰多菲征,瞳孔收缩和舒张交替扩张,是主动脉瓣反流的临床标志。它被认为是由于在主动脉瓣功能不全的背景下,由于宽脉压导致虹膜血管的生理性循环痉挛加剧。退行性心脏病和风湿性心脏病在印度农村非常常见,这些患者往往在初级保健医生那里出现并发症。在此,作者报告了一位34岁的孕妇,她表现为急性心力衰竭,并在检查中发现了Landolfi征。随后立即进行多普勒超声心动图诊断为严重主动脉反流。患者在抗衰竭药物治疗下病情稳定,并密切监测母婴健康。作者希望得出结论,声称心脏病学的床边临床培训将永远保持重要地位,尤其是在不复杂的初级卫生保健机构处理患者时。此外,他们还认为,应该在这些中心提供超声心动图等基本工具支持。
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引用次数: 0
Insight into the challenges in diagnosis and management of infections in adults with primary immunodeficiency diseases: A study from AIIMS, New Delhi 了解成人原发性免疫缺陷疾病感染的诊断和管理挑战:来自新德里AIIMS的一项研究
Bharath Gangadharaiah, M. Sahu, Arvind Kumar, P. Ranjan, P. Sethi, N. Wig
Primary immunodeficiency diseases (PIDDs) comprise a group of genetic disorders which are characterized by abnormalities involving one or more components of the immune system. Most of them are diagnosed in children and adolescents. Advancement in medical management has resulted in most of these patients living till adulthood. Moreover, few PIDD patients are diagnosed for the first time in their adulthood. In most of the developing countries, where the prevalence of infectious disease is quite high, diagnosis of patients presenting in adulthood with PIDDs poses a major challenge. The diagnosis may be delayed or even missed altogether when they present late in adulthood. Hence, having in-depth knowledge regarding common PIDDs seen in this age group, the natural course of these diseases and the wide range of clinical spectrum with which these patients can present is quite imperative for a physician dealing with such patients. This case series provides the details of three such PIDD patients presenting in the late adolescence and adult age group, along with a comprehensive review on the common and uncommon infections occurring among PIDD patients in this age group.
原发性免疫缺陷疾病(PIDDs)包括一组遗传性疾病,其特征是涉及免疫系统的一个或多个组成部分的异常。大多数是在儿童和青少年中被诊断出来的。医疗管理的进步使这些患者大多活到成年。此外,很少有PIDD患者在成年后首次被诊断出来。在传染病流行率相当高的大多数发展中国家,成年期pidd患者的诊断是一项重大挑战。当他们在成年后期出现时,诊断可能会延迟甚至完全错过。因此,对这一年龄组常见的pidd有深入的了解,这些疾病的自然过程和这些患者可能表现出的广泛的临床谱,对于治疗这类患者的医生来说是非常必要的。本病例系列提供了3例出现在青春期晚期和成年年龄组的此类PIDD患者的详细信息,并对该年龄组PIDD患者中常见和不常见的感染进行了全面回顾。
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引用次数: 0
Mental health status among the family members of COVID-19 patients in Jabalpur District Madhya Pradesh: A Cross-sectional study 中央邦贾巴尔普尔地区COVID-19患者家庭成员的心理健康状况:一项横断面研究
Arvind Sharma, T. Singh, Aditi Bharti, Richa Sharma, Deepali Soni, P. Dubey
Objective: The objective of the study was to assess mental health status among the family members of the COVID-19 patients and the severity of depression in the Jabalpur district, Madhya Pradesh. Setting and Design: A cross-sectional study was conducted among family members of COVID-19 patients admitted at a tertiary care center. Methodology: Out of 160 respondents, 130 have participated, and the remaining 30 were dropouts. Participants included one member from each family of confirmed COVID-19 cases admitted at a tertiary care hospital, preferably their spouse or first-degree members living in the same house, aged 18 years and above. The Patient Health Questionnaire-9 was used to determine depression and was completed through a telephonic platform survey. Statistical Analysis Used: SPSS 20.0 statistical software was used to analyze the data. Significance was determined at P < 0.05 and 95% confidence interval. Results: The majority of respondents, 61.5%, screened positive for depression. Among them, 46 were mildly depressed (35.4%), 28 were moderately depressed (21.5%), 4 were moderately severe depressed (3.1%), and two were severely depressed (1.5%). Females had approximately 4 times higher risk for depressive symptoms (P = 0.001). Conclusion: There is a need to emphasize the mental health of this vulnerable population. Our findings are also crucial in enabling the government to allocate health resources and offer appropriate treatment for family members who suffer mental health problems during the COVID-19 pandemic or any other infectious disease outbreak in the future.
目的:本研究的目的是评估中央邦贾巴尔普尔地区COVID-19患者家庭成员的心理健康状况和抑郁症的严重程度。设置和设计:对在三级保健中心住院的COVID-19患者的家庭成员进行了横断面研究。调查方法:在160名调查对象中,130人参加了调查,其余30人是辍学生。参与者包括来自三级医院收治的新冠肺炎确诊病例的每个家庭的一名成员,最好是其配偶或居住在同一屋檐下的一级家庭成员,年龄在18岁及以上。患者健康问卷-9用于确定抑郁症,并通过电话平台调查完成。统计分析方法:采用SPSS 20.0统计软件对数据进行分析。以P < 0.05和95%置信区间确定显著性。结果:61.5%的受访者抑郁症筛查呈阳性。其中轻度抑郁46例(35.4%),中度抑郁28例(21.5%),中度重度抑郁4例(3.1%),重度抑郁2例(1.5%)。女性出现抑郁症状的风险大约是男性的4倍(P = 0.001)。结论:有必要重视这一弱势群体的心理健康。我们的发现对于使政府能够在COVID-19大流行或未来任何其他传染病爆发期间分配卫生资源并为患有精神健康问题的家庭成员提供适当的治疗也至关重要。
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引用次数: 3
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Journal of primary care specialties : official publication of the Institute of Family Medicine and Primary Care
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