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Knowledge, attitude, and practices of patient relatives regarding face masks in COVID-19 pandemic: A single-center cross-sectional study COVID-19大流行患者家属对口罩的知识、态度和实践:一项单中心横断面研究
Anirban Das, Preetam Goswami, Pronoy Sen
Objective: Coronavirus disease (COVID-19) pandemic was declared as a global pandemic on the March 12, 2020. Face masks are recommended to control COVID-19 transmission, whose filtering capability depends on the different materials mask is made of and its structural design. The knowledge, attitudes, and practices (KAP) toward facemasks play an integral role to understand society's readiness to accept and follow preventive guidelines. The main objective was to estimate various factors affecting KAP in the study population and also to calculate the knowledge score (KS) from the data. Materials and Methods: A cross-sectional study was conducted using a questionnaire. The questionnaire consisted of 5, 3, and 5 questions on KAP, respectively. Score of 1 was assigned to the correct response and score of 0 for the incorrect response. Accordingly, score of <3 depicted that individual had poor knowledge, while ≥3 indicated good knowledge. Data were analyzed using appropriate descriptive statistical tests. An independent t-test was used to determine differences in groups concerning mask usage. Results: Out of total 110 participants, majority were males (53.6%). Majority (78.2%) had a good KS and the mean KS was 3.41. The KS was higher in the 18–40 years age group (P = 0.026), males (P = 0.030), literate people (P = 0.011), and in the urban population (P = 0.021). Majority (97.3%) knew that it is necessary to wear face mask during this pandemic. Participants with higher KS covered both their nose and mouth with face mask and also, they removed their mask completely while eating. Conclusions: Most of the patient's relatives had satisfactory knowledge, a positive attitude, and good practices toward the use of face masks to limit the spread of COVID-19 in the community.
目的:2020年3月12日,新型冠状病毒病(COVID-19)大流行宣布为全球大流行。建议使用口罩控制新冠病毒传播,口罩的过滤能力取决于口罩的材质和结构设计。关于口罩的知识、态度和实践(KAP)在了解社会是否愿意接受和遵循预防指南方面发挥着不可或缺的作用。主要目的是估计影响研究人群KAP的各种因素,并从数据中计算知识得分(KS)。材料与方法:采用问卷调查法进行横断面研究。问卷分别包括5题、3题和5题。正确回答得1分,错误回答得0分。因此,得分<3表示个体知识较差,得分≥3表示个体知识较好。使用适当的描述性统计检验对数据进行分析。采用独立t检验来确定各组在口罩使用方面的差异。结果:110名参与者中,男性居多(53.6%)。绝大多数(78.2%)有良好的KS,平均KS为3.41。KS在18-40岁年龄组(P = 0.026)、男性(P = 0.030)、文化人(P = 0.011)和城市人口(P = 0.021)中较高。大多数人(97.3%)知道在这次大流行期间有必要戴口罩。高KS的参与者用口罩遮住了鼻子和嘴巴,而且他们在吃东西的时候完全摘下了口罩。结论:大多数患者家属对佩戴口罩限制COVID-19在社区传播的知识、态度和做法满意。
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引用次数: 0
Corticosteroid-induced avascular bone necrosis and possible association with prior COVID-19 infection 皮质类固醇诱导的无血管性骨坏死及其与既往COVID-19感染的可能关联
Kanisha Shah, D. Shukla, R. Khan, S. Malhotra
Corticosteroid is a frequent implicating factor for the development of avascular bone necrosis (AVN). The etiology of corticosteroid-induced AVN is not fully understood, but it includes fat hypertrophy, fat embolism, and intravascular coagulation that causes obstruction of blood supply to the bone. This association can be carried forward for COVID-19 as well since it is also a microvascular disease. Suffering from COVID-19 and prescription of glucocorticoids could both be responsible for AVN. Early recognition of this complication is essential as the prognosis is affected by the stage of the disease.
皮质类固醇是发生无血管性骨坏死(AVN)的常见因素。皮质类固醇诱导AVN的病因尚不完全清楚,但它包括脂肪肥大、脂肪栓塞和血管内凝血,导致骨供血受阻。这种关联也可以延续到COVID-19,因为它也是微血管疾病。患有COVID-19和服用糖皮质激素都可能导致AVN。早期识别这种并发症是必不可少的,因为预后受疾病分期的影响。
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引用次数: 0
Are we missing giant cell arteritis? 我们错过巨细胞动脉炎了吗?
D. Chakraborty, K. Sundar, Khizar Syed
Giant cell arteritis (GCA) is an immune-mediated vasculitis with intra and extracranial involvement commonly seen in the elderly population. However, a subgroup of patients may present with constitutional symptoms only called “masked GCA.” We diagnosed and successfully treated a patient who initially presented with cachexia, cognitive impairment, and seizure. Clinicians need to be very suspicious about the entity, as a miss can lead to life-threatening complications such as stroke, arterial dissection, and even aneurysm rupture (besides visual impairment). Although GCA involves medium and large vessels, small vessel vasculitis is also possible in GCA (as in our case). Hence, GCA may involve patients in their fifties and may present with a wide spectrum of intracranial and extracranial clinical manifestations.
巨细胞动脉炎(GCA)是一种免疫介导的血管炎,累及颅内内外,常见于老年人。然而,一个亚组的患者可能只表现为“隐蔽性GCA”的体质症状。我们诊断并成功治疗了一位最初表现为恶病质、认知障碍和癫痫发作的患者。临床医生需要对该实体非常怀疑,因为遗漏可能导致危及生命的并发症,如中风、动脉夹层,甚至动脉瘤破裂(除了视力损害外)。虽然GCA累及中、大血管,但小血管血管炎也可能发生(如本例)。因此,GCA可能涉及50多岁的患者,并可能表现出广泛的颅内和颅外临床表现。
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引用次数: 0
National medical commission and faculty evaluation – Aura of confusion 国家医学委员会和教员评价——混乱的光环
H. Gupta
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引用次数: 0
A study on patients with pleural effusion with emphasis on pleural fluid adenosine deaminase and pleural biopsy 胸腔积液患者的研究,重点是胸膜液腺苷脱氨酶和胸膜活检
A. Mandal, P. Sardar, P. Bar, Anirban Das
Background: Evaluation of adenosine deaminase (ADA) has emerged as a potential biochemical marker for the diagnosis of tuberculosis (TB). An increased level of ADA in blood generally indicates the presence of TB. This study aimed to evaluate the ADA level in pleural fluid with diagnostic accuracy in histologically confirmed patients of pleural TB. Materials and Methods: This prospective observational study included patients with a confirmed diagnosis of pleural effusion. Data related to demographics, clinical characteristics, sputum status, predominant cells, ADA levels, and pleural biopsy reports were recorded. Results: Of the 82 patients of exudative pleural effusion, 65 (79.3%) were men. The most common presenting symptoms were cough (87.8%), chest pain (67.1%), fever (64.6%), and shortness of breath (56.1%). The average ADA level was 66.5 IU/L. Pleural biopsy showed that 45.1% of patients were tubercular etiology, 34.1% of patients were malignant, and 20.7% were of nonspecific inflammatory origin. Totally 59.8% of patients had right-sided pleural effusion, whereas 40.2% of patients had left-sided pleural effusion. Majority of the TB patients (81.1%) with ADA level > 40 U/L were diagnosed with tubercular granuloma, whereas 41 patients with malignancy and other patients had ADA level < 40 U/L (P < 0.001). Conclusion: Evaluation of ADA level along with histopathological examination can be easily performed as the routine test in the diagnosis of TB.
背景:腺苷脱氨酶(ADA)的评估已成为诊断结核病(TB)的潜在生化标志物。血液中ADA水平升高通常表明存在结核病。本研究旨在评价组织学证实的胸膜结核患者胸膜液中ADA水平与诊断准确性的关系。材料和方法:本前瞻性观察研究纳入确诊为胸腔积液的患者。记录了人口统计学、临床特征、痰液状况、优势细胞、ADA水平和胸膜活检报告等相关数据。结果:82例胸腔渗出性积液中,男性65例(79.3%)。最常见的症状是咳嗽(87.8%)、胸痛(67.1%)、发热(64.6%)和呼吸短促(56.1%)。平均ADA水平为66.5 IU/L。胸膜活检显示45.1%的患者为结核性病因,34.1%的患者为恶性病因,20.7%的患者为非特异性炎症来源。右侧胸腔积液占59.8%,左侧胸腔积液占40.2%。ADA水平> 40 U/L的TB患者中,诊断为结核性肉芽肿的占81.1%,诊断为恶性肿瘤的占41例,其余ADA水平< 40 U/L的占41例(P < 0.001)。结论:ADA水平评价结合组织病理学检查可作为结核病诊断的常规检查。
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引用次数: 0
Holistic approach in managing tinnitus with yoga, naturopathy, and acupuncture interventions: A single-case report 整体方法在管理耳鸣与瑜伽,自然疗法和针灸干预:一个单一的案例报告
Maheshkannan Vanamoorthy, N. Mangaiarkarasi, N. Manavalan, Deenadayalan Boopalan
Tinnitus is a sensation of noise in the absence of an internal or external source often accompanied by hearing loss. A 45-year-old male patient visited our hospital outpatient department due to tinnitus in the left ear for the past 2 months and received integrated yoga and naturopathy treatments for 10 days. The Tinnitus Handicap Inventory (THI) severity scale and Visual Analog Scale (VAS) were assessed before starting interventions and on the 10th day. The severity of the tinnitus was reduced; THI scores decreased from Grade 3 (moderate) to Grade 2 (mild) and the VAS score for disturbed sleep reduced from 8 to 4.1. This case study is an effort to elicit the impact of yoga and naturopathy on managing tinnitus. Despite significant findings in this case, further studies with a larger sample size are required to manage tinnitus effectively with yoga and the naturopathy system of medicine.
耳鸣是一种在没有内部或外部来源的情况下的噪音感觉,通常伴有听力损失。患者男,45岁,因左耳耳鸣2个月来我院门诊就诊,接受瑜伽和自然疗法综合治疗10天。在干预开始前和第10天分别评估耳鸣障碍量表(THI)严重程度量表和视觉模拟量表(VAS)。耳鸣的严重程度有所减轻;THI评分从3级(中度)降至2级(轻度),睡眠障碍VAS评分从8分降至4.1分。本案例研究旨在探讨瑜伽和自然疗法对耳鸣的影响。尽管在这种情况下有重大发现,但需要进一步研究更大的样本量,以有效地管理耳鸣与瑜伽和医学自然疗法系统。
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引用次数: 0
Cutaneous adverse drug reactions in a tertiary care setup: A cross-sectional observational single-center-based study in Eastern India 三级医疗机构的皮肤药物不良反应:印度东部的一项横断面观察性单中心研究
Ritika Singh, Nikhil Era, Shatavisa Mukherjee, P. Paul, S. Bordoloi
Background: Cutaneous adverse drug reactions (cADRs) constitute a significant cause of mortality and morbidity, adding to the economic burden for the patients. cADRs have varied and diverse presentations of morphology and severity. The present study aimed to explore the spectrum of cADRs reported in a tertiary care setup in Eastern India. Methods: A cross-sectional, single-center-based observational study was undertaken which included all the patients reporting with suspected cADRs. The patient details, ADR characteristics, and other relevant details were noted. Detailed pharmacovigilance workup, including causality, severity, and preventability assessment, was performed. Data were statistically analyzed. Results: 0.16% incidence of cADRs was observed, with the most common form being urticaria, followed by fixed drug eruption, maculopapular rash, and erythroderma. The most common drug class suspected to cause cADR was antimicrobials, followed by corticosteroids and nonsteroidal anti-inflammatory drugs. While most reactions were of moderate grade in severity, majority of the reactions were under “possible” causal category. 22.1% of the reported cADRs were not preventable. Conclusion: Proper diagnosis and optimum management of cutaneous ADRs are critically challenging and important.
背景:皮肤药物不良反应(cADRs)是导致死亡和发病的重要原因,增加了患者的经济负担。cadr的形态和严重程度各不相同。本研究旨在探讨在印度东部三级医疗机构报告的cadr的频谱。方法:采用一项横断面、单中心的观察性研究,纳入所有报告疑似cadr的患者。记录患者详细情况、不良反应特征及其他相关细节。进行了详细的药物警戒检查,包括因果关系、严重程度和可预防性评估。对数据进行统计学分析。结果:cADRs发生率为0.16%,以荨麻疹最常见,其次为固定药疹、黄斑丘疹、红皮病。疑似引起cADR的最常见药物类别是抗菌素,其次是皮质类固醇和非甾体抗炎药。虽然大多数反应的严重程度为中度,但大多数反应属于“可能的”因果类别。22.1%的cadr是不可预防的。结论:皮肤不良反应的正确诊断和最佳处理具有重要的挑战性。
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引用次数: 0
Mediation effect of sleep quality and internet addiction on depression among indian medical graduate students: A cross-sectional study 睡眠质量和网络成瘾对印度医学研究生抑郁的中介作用:一项横断面研究
G. Meratwal, Praveena Tandon, Ashok Kumar
Introduction: There is a complex interaction between poor sleep quality, Internet addiction (IA), and depression. This study aimed to determine whether sleep quality or IA statistically mediates the association between the other two variables. Materials and Methods: This cross-sectional study was conducted from June 2022 to October 2022 in a medical college in Ajmer, Rajasthan. Data were collected from 400 undergraduate medical students. Data were collected using Depression, Anxiety, and Stress Scale-21, Pittsburgh Sleep Quality Index, and Young's IA tools. Data were analyzed by multivariate logistic regression and the PROCESS program in SPSS 20.0. Results: The mean (standard deviation) age of the students was 20.9 (1.68) years. About 43% of students (n = 174) had depression, 40.3% (n = 161) had poor sleep, and 54% (n = 216) had IA. The age of the students (adjusted odds ratio [aOR] = 1.92), screen time per day (aOR = 1.06), smoking (aOR = 13.20), sleep quality (aOR = 1.16), and IA (aOR = 11.64) were significantly associated with depression. IA mediated 30.55% of the indirect effect of sleep quality on depression, whereas sleep quality mediated 18.18% of the indirect effect of IA on depression. Conclusion: Sleep quality and IA have a differential independent indirect effect on the association between depression and the other variable. Programs and counseling sessions that promote mental health should also address the adverse impact of poor sleep and IA.
睡眠质量差、网络成瘾(IA)和抑郁症之间存在复杂的相互作用。本研究旨在确定睡眠质量或IA是否在统计上介导了其他两个变量之间的关联。材料和方法:本横断面研究于2022年6月至2022年10月在拉贾斯坦邦Ajmer的一所医学院进行。数据收集自400名医科本科生。使用抑郁、焦虑和压力量表-21、匹兹堡睡眠质量指数和Young's IA工具收集数据。数据采用多元逻辑回归和SPSS 20.0中的PROCESS程序进行分析。结果:学生平均(标准差)年龄为20.9(1.68)岁。约43% (n = 174)的学生患有抑郁症,40.3% (n = 161)的学生睡眠不足,54% (n = 216)的学生患有IA。学生年龄(校正优势比[aOR] = 1.92)、每天屏幕时间(aOR = 1.06)、吸烟(aOR = 13.20)、睡眠质量(aOR = 1.16)、IA (aOR = 11.64)与抑郁显著相关。IA介导睡眠质量对抑郁间接效应的30.55%,而睡眠质量介导IA对抑郁间接效应的18.18%。结论:睡眠质量和IA对抑郁与其他变量的关联有差异的独立间接影响。促进心理健康的项目和咨询会议也应该解决睡眠不足和IA的不利影响。
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引用次数: 0
Assessment of perceived stress during corona (COVID-19) pandemic among health-care workers 冠状病毒(COVID-19)大流行期间卫生保健工作者感知压力的评估
Akhilesh K. Jain, Naman Jain, Manish Goyal, A. Goyal, K. Yadav, Rakshit Yadav
Introduction: The pandemic of COVID-19 has caused both physical and psychological suffering not only to the general population but also to health-care workers (HCWs). Assessment of mental stress in HCWs is important as they have played a crucial role during this pandemic. Hence, this study was planned to assess the level of stress in HCWs during the COVID-19 pandemic. Materials and Methods: A total of 312 subjects were included by purposive sampling method in this cross-sectional study. A self-designed pro forma was used to collect sociodemographic details of subjects. The Hindi version of the perceived stress scale (PSS)-10 was used to assess stress. The data were analyzed using IBM SPSS version 28. Results: The level of perceived stress was significantly higher in HCWs working in government hospitals and quarantine services. Similarly, paramedical personnel and nursing staff were found to have more median PSS levels (18 and 16, respectively) as compared to doctors and others (15 and 16, respectively), and this observation was also significant in our study (P = 0.007). Although not statistically significant, stress was more among female HCWs, those from nuclear family, younger age group, and those who had been taking treatment for some psychiatric illness. Conclusion: There is a need to assess the ongoing stress among HCWs and address the contributing factors, thus enabling them to perform their duties more effectively and optimally.
导言:2019冠状病毒病大流行不仅给普通民众,而且给卫生保健工作者造成了身心痛苦。评估卫生保健工作者的精神压力非常重要,因为他们在本次大流行期间发挥了至关重要的作用。因此,本研究计划评估COVID-19大流行期间医护人员的压力水平。材料与方法:本研究采用目的抽样方法,共纳入312名被试。使用自行设计的形式来收集受试者的社会人口学细节。使用印地语版的感知压力量表(PSS)-10来评估压力。数据分析采用IBM SPSS version 28。结果:在公立医院和检疫机构工作的卫生保健工作者的感知压力水平显著较高。同样,与医生和其他人员(分别为15和16)相比,医护人员和护理人员的PSS中位数(分别为18和16)更高,这一观察结果在我们的研究中也具有显著性(P = 0.007)。尽管没有统计学上的显著差异,但女性卫生保健工作者、核心家庭成员、年轻年龄组和接受过某些精神疾病治疗的人的压力更大。结论:有必要对医护人员的持续压力进行评估,并解决造成压力的因素,从而使医护人员更有效、更优化地履行职责。
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引用次数: 0
Acute undifferentiated fever presenting as multi-organ dysfunction: Narrowing the differential diagnosis 以多器官功能障碍为表现的急性未分化发热:缩小鉴别诊断范围
Monica Gupta, Sanjana Sharma, S. Lehl, N. Singla
Introduction: Acute undifferentiated fever (AUF) in India is highly prevalent in the monsoon and postmonsoon periods. AUF may trigger potentially fatal illnesses with acute-onset complications; therefore, this study was carried out to recognize the common forms of organ dysfunction in tropical vector-borne diseases which present as AUF. Materials and Methods: A 20-month prospective study was conducted to estimate the incidence of multi-organ dysfunction syndrome (MODS) among the common causes of AUF. The association of mortality with MODS patterns was also determined. All nonparametric variables were compared using Chi-square and Kruskal–Wallis. Bivariate as well as multivariate logistic regression analyses were performed to find the predictors of mortality/poor outcome. Results: Scrub typhus had the highest incidence of MODS and highest mortality with simultaneous hepatic and renal involvement in 35.8%, followed by hepatic involvement with acute respiratory distress syndrome (ARDS) in 33.9% and hepatic involvement with shock in 32%. Patients of MODS with acute kidney injury (AKI), shock, or sepsis had higher mortality rates. Conclusion: AUF presents with multiple overlapping manifestations which are difficult to discern clinically into specific etiologies, especially once MODS sets in. However, we observed statistically higher odds of the patient having scrub typhus as the cause of AUF when simultaneous hepatitis, AKI, ARDS, and shock were present.
简介:急性未分化热(AUF)在印度非常普遍,在季风和季风后时期。AUF可能引发潜在的致命性疾病,并伴有急性并发症;因此,本研究旨在识别热带媒介传播疾病中以AUF表现的常见器官功能障碍形式。材料和方法:我们进行了一项为期20个月的前瞻性研究,以估计多器官功能障碍综合征(MODS)在AUF常见病因中的发生率。死亡率与MODS模式的关系也被确定。所有非参数变量采用卡方和Kruskal-Wallis进行比较。进行双变量和多变量逻辑回归分析以寻找死亡率/不良预后的预测因素。结果:恙虫病并发肝肾累及MODS发生率最高,死亡率最高(35.8%),其次为肝累及急性呼吸窘迫综合征(ARDS)(33.9%)和肝累及休克(32%)。MODS合并急性肾损伤(AKI)、休克或败血症的患者死亡率较高。结论:AUF有多种重叠表现,临床上难以区分具体病因,尤其是MODS。然而,我们在统计上观察到,当同时存在肝炎、AKI、ARDS和休克时,患者以恙虫病为AUF原因的几率更高。
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引用次数: 0
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Journal of primary care specialties : official publication of the Institute of Family Medicine and Primary Care
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