Butruz Sarkis Simão, Denis Damião Costa, M. C. Cangussú, B. Sotto-Maior, R. Devita, J. D. de Carvalho, Igor da Silva Brum
The osseointegration process between the host’s bone tissue and the titanium implant is the key to success of implantology. The literature highlights the high success rate of osseointegrated implants, which is above 90%, and warns that some failures may occur, and every professional may face some inevitable failure. A longitudinal study was designed to evaluate the success rate of osseointegrated implants by taking into account the early failure of osseointegration. The study’s population included a convenience sample of all patients attending in four municipalities in the state of Paraíba, Brazil, belonging to the Brazilian Unified Health System (SUS) and those who underwent implant placements between November 2015 and November 2018 and were followed-up until March 2020. Data were extracted from the National Registry of Health Establishments (CNES), a database that contains data on all Brazilian health institutions. Of the total placed implants, 1.88% failed before prosthetic rehabilitation, corresponding to a success rate of 98.12%. The success and failure rates by anatomical region were also evaluated, which revealed, respectively, the values for the anterior maxilla (95.52% and 4.48%), posterior maxilla (97.53% and 2.47%), anterior mandible (97.13% and 2.87%), and posterior mandible (98.90% and 1.10%). We conclude that the posterior mandible performed better than the other bone types and anatomical regions. The anterior region of the maxilla was the one that presented the worst performance. Moreover, when compared, the posterior maxilla performed similarly to the anterior mandible and better than the anterior maxilla.
{"title":"Observational Study on the Success Rate of Osseointegration: A Prospective Analysis of 15,483 Implants in a Public Health Setting","authors":"Butruz Sarkis Simão, Denis Damião Costa, M. C. Cangussú, B. Sotto-Maior, R. Devita, J. D. de Carvalho, Igor da Silva Brum","doi":"10.3390/biomed2040033","DOIUrl":"https://doi.org/10.3390/biomed2040033","url":null,"abstract":"The osseointegration process between the host’s bone tissue and the titanium implant is the key to success of implantology. The literature highlights the high success rate of osseointegrated implants, which is above 90%, and warns that some failures may occur, and every professional may face some inevitable failure. A longitudinal study was designed to evaluate the success rate of osseointegrated implants by taking into account the early failure of osseointegration. The study’s population included a convenience sample of all patients attending in four municipalities in the state of Paraíba, Brazil, belonging to the Brazilian Unified Health System (SUS) and those who underwent implant placements between November 2015 and November 2018 and were followed-up until March 2020. Data were extracted from the National Registry of Health Establishments (CNES), a database that contains data on all Brazilian health institutions. Of the total placed implants, 1.88% failed before prosthetic rehabilitation, corresponding to a success rate of 98.12%. The success and failure rates by anatomical region were also evaluated, which revealed, respectively, the values for the anterior maxilla (95.52% and 4.48%), posterior maxilla (97.53% and 2.47%), anterior mandible (97.13% and 2.87%), and posterior mandible (98.90% and 1.10%). We conclude that the posterior mandible performed better than the other bone types and anatomical regions. The anterior region of the maxilla was the one that presented the worst performance. Moreover, when compared, the posterior maxilla performed similarly to the anterior mandible and better than the anterior maxilla.","PeriodicalId":93816,"journal":{"name":"SPG biomed","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81326200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Giarmatzis, S. Fotiadou, E. Giannakou, Christos Kokkotis, Theodora D Fanaradelli, S. Kordosi, K. Vadikolias, N. Aggelousis
Research of post-stroke locomotion via musculoskeletal (MSK) modeling has offered an unprecedented insight into pathological muscle function and its interplay with skeletal geometry and external stimuli. Advances in solving the dynamical system of post-stroke effort and the generic MSK models used have triggered noticeable improvements in simulating muscle activation dynamics of stroke populations. However, a review of these advancements to inform the scientific community has yet to be made.: PubMed and Scopus databases were used to perform a thorough literature search to identify relevant articles since 2010. Here, we review MSK methods and practices—developed in the last ten years—that have been utilized to explore post-stroke locomotion and examine how their outcomes can inform clinical practice.: Out of the 44 articles that were initially found, 19 were reviewed. The articles were categorized with respect to the type of assessment the MSK methods were used for.: This review notes the considerable competence of existing methods to address post-stroke motion deficits. However, the drawbacks in the implementation of such methods by non-experts due to the high skill demand and the lack of mature software technology for further dissemination of practices and outcomes remain non-trivial.
{"title":"Understanding Post-Stroke Movement by Means of Motion Capture and Musculoskeletal Modeling: A Scoping Review of Methods and Practices","authors":"G. Giarmatzis, S. Fotiadou, E. Giannakou, Christos Kokkotis, Theodora D Fanaradelli, S. Kordosi, K. Vadikolias, N. Aggelousis","doi":"10.3390/biomed2040032","DOIUrl":"https://doi.org/10.3390/biomed2040032","url":null,"abstract":"Research of post-stroke locomotion via musculoskeletal (MSK) modeling has offered an unprecedented insight into pathological muscle function and its interplay with skeletal geometry and external stimuli. Advances in solving the dynamical system of post-stroke effort and the generic MSK models used have triggered noticeable improvements in simulating muscle activation dynamics of stroke populations. However, a review of these advancements to inform the scientific community has yet to be made.: PubMed and Scopus databases were used to perform a thorough literature search to identify relevant articles since 2010. Here, we review MSK methods and practices—developed in the last ten years—that have been utilized to explore post-stroke locomotion and examine how their outcomes can inform clinical practice.: Out of the 44 articles that were initially found, 19 were reviewed. The articles were categorized with respect to the type of assessment the MSK methods were used for.: This review notes the considerable competence of existing methods to address post-stroke motion deficits. However, the drawbacks in the implementation of such methods by non-experts due to the high skill demand and the lack of mature software technology for further dissemination of practices and outcomes remain non-trivial.","PeriodicalId":93816,"journal":{"name":"SPG biomed","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72646559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cardiovascular diseases require extensive diagnostic tests and frequent physician visits. With the advance in signal processing and sensor technology, now it is possible to acquire vital signs from the human body and process the signal to extract features necessary to primarily diagnose symptoms of cardiovascular disease early. This can help prevent deadly health incidents such as heart attack and or stroke, as well as reduce the number of visits to a health care facility. The proper detection of an elevated ST segment of ECG wave at an early stage may save the patient from having a heart attack or ST elevated myocardial infarction later. The use of a variety of complementary biomedical sensors can lead to a better diagnosis than what is possible when a single sensor is used. This paper proposes a MATLAB GUI which can detect elevated ST segments of ECG waves and use information from a variety of biomedical sensors to bring forth a technique to assess heart health to predict potential heart failure conditions. The proposed technique used fusion among multiple biomedical sensors to reduce the false alarm in diagnosis. Data from the online dataset were used to show the effectiveness and promise of the proposed detection of elevated ST segments and diagnosis techniques using the GUI.
{"title":"Significance of Features from Biomedical Signals in Heart Health Monitoring","authors":"M. Mamun","doi":"10.3390/biomed2040031","DOIUrl":"https://doi.org/10.3390/biomed2040031","url":null,"abstract":"Cardiovascular diseases require extensive diagnostic tests and frequent physician visits. With the advance in signal processing and sensor technology, now it is possible to acquire vital signs from the human body and process the signal to extract features necessary to primarily diagnose symptoms of cardiovascular disease early. This can help prevent deadly health incidents such as heart attack and or stroke, as well as reduce the number of visits to a health care facility. The proper detection of an elevated ST segment of ECG wave at an early stage may save the patient from having a heart attack or ST elevated myocardial infarction later. The use of a variety of complementary biomedical sensors can lead to a better diagnosis than what is possible when a single sensor is used. This paper proposes a MATLAB GUI which can detect elevated ST segments of ECG waves and use information from a variety of biomedical sensors to bring forth a technique to assess heart health to predict potential heart failure conditions. The proposed technique used fusion among multiple biomedical sensors to reduce the false alarm in diagnosis. Data from the online dataset were used to show the effectiveness and promise of the proposed detection of elevated ST segments and diagnosis techniques using the GUI.","PeriodicalId":93816,"journal":{"name":"SPG biomed","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78516769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Do we have the right to wear masks during an infectious disease pandemic? If so, what is the underlying philosophical justification for this? During the COVID-19 pandemic, most people wore masks. Should the government be able to intervene to enforce mask wearing? It should be noted that the government’s encouragement to wear masks does not mean that people are encouraged to ignore them. In the field of public health ethics, many current debates boil down to establishing a balance between “individual freedom” and “the public good”. However, a clear definition of “the public good” has yet to emerge, which can make this debate difficult. Based on our philosophical analysis, we propose the following as a new right in the field of public health ethics: the “right to mask for self-protection”. Based on our proposed “right to mask for self-protection”, we offer a justification for the argument that all people have the right to wear a mask during an infectious disease pandemic or endemic.
{"title":"Mask-Wearing during the COVID-19 Pandemic: A Theoretical Analysis from the Perspective of Public Health Ethics","authors":"A. Akabayashi, A. Akabayashi, E. Nakazawa","doi":"10.3390/biomed2040030","DOIUrl":"https://doi.org/10.3390/biomed2040030","url":null,"abstract":"Do we have the right to wear masks during an infectious disease pandemic? If so, what is the underlying philosophical justification for this? During the COVID-19 pandemic, most people wore masks. Should the government be able to intervene to enforce mask wearing? It should be noted that the government’s encouragement to wear masks does not mean that people are encouraged to ignore them. In the field of public health ethics, many current debates boil down to establishing a balance between “individual freedom” and “the public good”. However, a clear definition of “the public good” has yet to emerge, which can make this debate difficult. Based on our philosophical analysis, we propose the following as a new right in the field of public health ethics: the “right to mask for self-protection”. Based on our proposed “right to mask for self-protection”, we offer a justification for the argument that all people have the right to wear a mask during an infectious disease pandemic or endemic.","PeriodicalId":93816,"journal":{"name":"SPG biomed","volume":"5 2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90060656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hiroto Honda, Naoko Hashimoto, M. Zenibayashi, Akihiko Takeda, T. Takeuchi, Akane Yamamoto, Y. Hirota
This preliminary study aimed to investigate physical activity (PA) and glycemic control changes in Japanese adult females with type 1 diabetes (T1D) before the COVID-19 pandemic and one year later. Twelve females with T1D who used continuous glucose monitoring devices and initially volunteered for the study between February and March 2020 were included. PA data, obtained using a triaxial accelerometer, and glycemic control, including glycated hemoglobin (HbA1c), glycoalbumin (GA), mean 24-h sensor glucose (SG), time above range (TAR > 180 mg/dL), time in range (TIR 70–180 mg/dL), and time below range (TBR < 70 mg/dL), were analyzed. One year later, long (≥10 min) bouts of moderate-to-vigorous-intensity PA and daily steps decreased by 35.1% and 6.0%, respectively, and TAR increased from 23.5% to 29.0%. Additionally, an increase in prolonged (≥30 min) sedentary behavior correlated with a decrease in TBR and an increase in mean 24-h SG, GA, and the GA/HbA1c ratio. Furthermore, a decrease in daily energy consumption correlated with a decrease in TIR. These results indicate that some forms of PA in Japanese T1D adults have not returned to their pre-pandemic status, even in the same season one year later, which could worsen glycemic control.
{"title":"Changes in Physical Activity and Glycemic Control before and after the Declaration of the State of Emergency Due to the COVID-19 Pandemic in Japanese Adult Females with Type 1 Diabetes: A 1-Year Follow-Up Study","authors":"Hiroto Honda, Naoko Hashimoto, M. Zenibayashi, Akihiko Takeda, T. Takeuchi, Akane Yamamoto, Y. Hirota","doi":"10.3390/biomed2040029","DOIUrl":"https://doi.org/10.3390/biomed2040029","url":null,"abstract":"This preliminary study aimed to investigate physical activity (PA) and glycemic control changes in Japanese adult females with type 1 diabetes (T1D) before the COVID-19 pandemic and one year later. Twelve females with T1D who used continuous glucose monitoring devices and initially volunteered for the study between February and March 2020 were included. PA data, obtained using a triaxial accelerometer, and glycemic control, including glycated hemoglobin (HbA1c), glycoalbumin (GA), mean 24-h sensor glucose (SG), time above range (TAR > 180 mg/dL), time in range (TIR 70–180 mg/dL), and time below range (TBR < 70 mg/dL), were analyzed. One year later, long (≥10 min) bouts of moderate-to-vigorous-intensity PA and daily steps decreased by 35.1% and 6.0%, respectively, and TAR increased from 23.5% to 29.0%. Additionally, an increase in prolonged (≥30 min) sedentary behavior correlated with a decrease in TBR and an increase in mean 24-h SG, GA, and the GA/HbA1c ratio. Furthermore, a decrease in daily energy consumption correlated with a decrease in TIR. These results indicate that some forms of PA in Japanese T1D adults have not returned to their pre-pandemic status, even in the same season one year later, which could worsen glycemic control.","PeriodicalId":93816,"journal":{"name":"SPG biomed","volume":"876 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76285051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Patellar tendinopathy is a common injury characterized by progressive activity-related anterior knee pain. It is highly prevalent in sports which involve jumping and changing direction. The aim of this paper is to review recent high-quality evidence regarding the effectiveness of physical therapy in the treatment of patellar tendinopathy. Randomized controlled trials (n = 22) researching the effects of exercise therapy, physical agents, and soft tissue techniques were included. The results show that exercise therapy is the most effective. While eccentric exercise is commonly used, very promising progressive tendon-loading exercise therapy programs are recently emerging. Extracorporeal shock wave therapy, dry needling, and orthoses are no more effective than eccentric exercises or placebo groups. Isometric and isotonic exercise, patellar strap, sports tape, and kinesiotaping have a short-term effect on functional improvement and pain reduction, while progressive tendon-loading exercise, dry needling, platelet-rich plasma, and extracorporeal shock wave therapy have long-term effects.
{"title":"Conservative Treatments for Patellar Tendinopathy: A Review of Recent High-Quality Evidence","authors":"Jerneja Čobec, Ž. Kozinc","doi":"10.3390/biomed2040028","DOIUrl":"https://doi.org/10.3390/biomed2040028","url":null,"abstract":"Patellar tendinopathy is a common injury characterized by progressive activity-related anterior knee pain. It is highly prevalent in sports which involve jumping and changing direction. The aim of this paper is to review recent high-quality evidence regarding the effectiveness of physical therapy in the treatment of patellar tendinopathy. Randomized controlled trials (n = 22) researching the effects of exercise therapy, physical agents, and soft tissue techniques were included. The results show that exercise therapy is the most effective. While eccentric exercise is commonly used, very promising progressive tendon-loading exercise therapy programs are recently emerging. Extracorporeal shock wave therapy, dry needling, and orthoses are no more effective than eccentric exercises or placebo groups. Isometric and isotonic exercise, patellar strap, sports tape, and kinesiotaping have a short-term effect on functional improvement and pain reduction, while progressive tendon-loading exercise, dry needling, platelet-rich plasma, and extracorporeal shock wave therapy have long-term effects.","PeriodicalId":93816,"journal":{"name":"SPG biomed","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86031731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Culqui, Josep Ortega Segura, Elisabeth Da Costa-Venancio, A. Renom-Guiteras, Esther Roquer, Sherly Melissa Muñoz Tejada, P. Rodríguez, Adilis L. Alba Travieso, Isis Medrano, Lizzeth Canchucaja-Gutarra, Marta Herrero-Torrus, Paula Jurado-Marín, M. Marín-Casino, Rosa Ana Sabaté-García, Cristina Roqueta-Guillen, María del Carmen Martínez, G. de Febrer, J. López-Bueno, M. Navas-Martín, César Garriga Fuentes, J. Caylà
Background: To determine risk factors of death in diagnosed patients with COVID-19 who were aged ≥60 years and could not benefit from intubation and mechanical ventilation. Methods: Retrospective multicentre study including all patients with COVID-19 admitted to four medium-stay centres in Catalonia (March-June 2020). At the multivariate level, we calculated hazard ratios (HR) with 95% confidence intervals (CI) to determine risk factors associated with mortality. Results: 683 patients were included, of whom 227 died (case fatality rate of 33%, reaching 42% in patients of more than 90 years). Mean survival was 21.92 (20.98–22.86) days. Factors associated with death were fever (HR:1.5 (1.06–2.13)), malaise (HR:1.4 (1.04–1.99)), dyspnoea (HR:1.98 (1.41–2.79)) and atrial fibrillation (HR:1.45 (1.03–2.05)), while coughing (HR: 0.66 (0.46–0.94)), diarrhoea (HR:0.46 (0.23–0.92)), dyslipidaemia (HR:0.47 (0.28–0.82)), and receiving antithrombotic treatment (HR:0.56 (0.40–0.78)) had a protective effect. The analysis by age group showed that other factors were uniquely associated with each age group, such as chronic obstructive pulmonary disease at 60–74 years and polypharmacy at 75–90 years, among other factors. Conclusions: Case fatality in COVID-19 patients who could not benefit from intubation and mechanical ventilation was exceptional. Clinical manifestations such as fever, malaise, dyspnoea and atrial fibrillation helped to identify patients at higher risk of mortality, while antithrombotic treatment had a protective effect. Although some symptoms are very general regarding COVID-19, in the context of the first wave without vaccination, when not much was known about the disease, such symptoms could be useful.
{"title":"Risk Factors Associated with the Mortality of COVID-19 Patients Aged ≥60 Years Neither Intubated nor Treated with Mechanical Ventilation: A Multicentre Retrospective Cohort Study during the First Wave in Spain","authors":"D. Culqui, Josep Ortega Segura, Elisabeth Da Costa-Venancio, A. Renom-Guiteras, Esther Roquer, Sherly Melissa Muñoz Tejada, P. Rodríguez, Adilis L. Alba Travieso, Isis Medrano, Lizzeth Canchucaja-Gutarra, Marta Herrero-Torrus, Paula Jurado-Marín, M. Marín-Casino, Rosa Ana Sabaté-García, Cristina Roqueta-Guillen, María del Carmen Martínez, G. de Febrer, J. López-Bueno, M. Navas-Martín, César Garriga Fuentes, J. Caylà","doi":"10.3390/biomed2030027","DOIUrl":"https://doi.org/10.3390/biomed2030027","url":null,"abstract":"Background: To determine risk factors of death in diagnosed patients with COVID-19 who were aged ≥60 years and could not benefit from intubation and mechanical ventilation. Methods: Retrospective multicentre study including all patients with COVID-19 admitted to four medium-stay centres in Catalonia (March-June 2020). At the multivariate level, we calculated hazard ratios (HR) with 95% confidence intervals (CI) to determine risk factors associated with mortality. Results: 683 patients were included, of whom 227 died (case fatality rate of 33%, reaching 42% in patients of more than 90 years). Mean survival was 21.92 (20.98–22.86) days. Factors associated with death were fever (HR:1.5 (1.06–2.13)), malaise (HR:1.4 (1.04–1.99)), dyspnoea (HR:1.98 (1.41–2.79)) and atrial fibrillation (HR:1.45 (1.03–2.05)), while coughing (HR: 0.66 (0.46–0.94)), diarrhoea (HR:0.46 (0.23–0.92)), dyslipidaemia (HR:0.47 (0.28–0.82)), and receiving antithrombotic treatment (HR:0.56 (0.40–0.78)) had a protective effect. The analysis by age group showed that other factors were uniquely associated with each age group, such as chronic obstructive pulmonary disease at 60–74 years and polypharmacy at 75–90 years, among other factors. Conclusions: Case fatality in COVID-19 patients who could not benefit from intubation and mechanical ventilation was exceptional. Clinical manifestations such as fever, malaise, dyspnoea and atrial fibrillation helped to identify patients at higher risk of mortality, while antithrombotic treatment had a protective effect. Although some symptoms are very general regarding COVID-19, in the context of the first wave without vaccination, when not much was known about the disease, such symptoms could be useful.","PeriodicalId":93816,"journal":{"name":"SPG biomed","volume":"110 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85340303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Football is characterized as a contact sport that increases the risk of injury. For the reduction of injuries, health care providers created a warm-up program that is called the FIFA11+. This is a 20 min warm-up program that has the goal of preventing injuries. This literature review investigated the effects of FIFA11+ on injury prevention and performance in football players. A systematic search was performed in three scientific databases (Pubmed, Scopus, and Physiotherapy Evidence Database (PEDro)) and one search engine (Google Scholar) from inception to June 2022. Relevant studies published in the English language were extracted, evaluated, and independently rated for methodological quality (PEDro scale). Overall, 10 randomized controlled trials were analyzed and their outcomes are discussed. Through the analysis of the studies, it was observed that the groups which performed the FIFA 11+ warm-up program had fewer incidents of injuries. In addition, the athletes of these groups increased their performance, especially in balance, proprioception, and strength of hamstrings. After the analysis, the results and limitations of the randomized controlled trials are discussed. Finally, this review suggests the inclusion of the FIFA 11+ in training sessions, and future recommendations are provided for the next trials for the maximization of their reliability.
{"title":"The Effect of the FIFA 11+ on Injury Prevention and Performance in Football: A Systematic Review with Meta-Analysis","authors":"Theodosis Vlachas, E. Paraskevopoulos","doi":"10.3390/biomed2030026","DOIUrl":"https://doi.org/10.3390/biomed2030026","url":null,"abstract":"Football is characterized as a contact sport that increases the risk of injury. For the reduction of injuries, health care providers created a warm-up program that is called the FIFA11+. This is a 20 min warm-up program that has the goal of preventing injuries. This literature review investigated the effects of FIFA11+ on injury prevention and performance in football players. A systematic search was performed in three scientific databases (Pubmed, Scopus, and Physiotherapy Evidence Database (PEDro)) and one search engine (Google Scholar) from inception to June 2022. Relevant studies published in the English language were extracted, evaluated, and independently rated for methodological quality (PEDro scale). Overall, 10 randomized controlled trials were analyzed and their outcomes are discussed. Through the analysis of the studies, it was observed that the groups which performed the FIFA 11+ warm-up program had fewer incidents of injuries. In addition, the athletes of these groups increased their performance, especially in balance, proprioception, and strength of hamstrings. After the analysis, the results and limitations of the randomized controlled trials are discussed. Finally, this review suggests the inclusion of the FIFA 11+ in training sessions, and future recommendations are provided for the next trials for the maximization of their reliability.","PeriodicalId":93816,"journal":{"name":"SPG biomed","volume":"86 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91428822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lymphomas have been increasing at an alarming rate globally and causing deaths worldwide due to the lack of effective therapies. Among different pharmacological agents, selenium (Se) and selenium-related compounds are widely tested and have gained interest as anticancer agents due to their selectivity to cancer and high efficacy for lymphoma treatment over recent decades. Se is a trace non-metallic element identified as an essential micronutrient that mediates a range of biological functions after incorporation into selenoproteins (SePs), and thus affects the overall quality of human health. Specifically, low levels of Se in serum have been linked with aberrant immune functions, cancer, inflammatory diseases, and predictive of worse outcomes in patients with hematological malignancies including lymphoma. Over the past few years, a number of promising selenium compounds (SeCs) have been developed to mimic and alter the functions of SePs to achieve pharmacological interventions such as anticancer, antioxidant, and anti-inflammatory activities with minimal adverse effects by suitable chemical substitution. Here, we have reviewed various lymphoma types and their molecular characterization, along with emphasis on the potential role of Se and SeCs as anti-cancer agents for lymphoma treatment. In addition, we have discussed various pros and cons associated with the usage of Se/SeCs for selectively targeting cancers including lymphomas.
{"title":"Chemopreventive Effects of Selenium and Selenocompounds in the Treatment of Lymphoma","authors":"Upendarrao Golla, Siva Dallavalasa","doi":"10.3390/biomed2030025","DOIUrl":"https://doi.org/10.3390/biomed2030025","url":null,"abstract":"Lymphomas have been increasing at an alarming rate globally and causing deaths worldwide due to the lack of effective therapies. Among different pharmacological agents, selenium (Se) and selenium-related compounds are widely tested and have gained interest as anticancer agents due to their selectivity to cancer and high efficacy for lymphoma treatment over recent decades. Se is a trace non-metallic element identified as an essential micronutrient that mediates a range of biological functions after incorporation into selenoproteins (SePs), and thus affects the overall quality of human health. Specifically, low levels of Se in serum have been linked with aberrant immune functions, cancer, inflammatory diseases, and predictive of worse outcomes in patients with hematological malignancies including lymphoma. Over the past few years, a number of promising selenium compounds (SeCs) have been developed to mimic and alter the functions of SePs to achieve pharmacological interventions such as anticancer, antioxidant, and anti-inflammatory activities with minimal adverse effects by suitable chemical substitution. Here, we have reviewed various lymphoma types and their molecular characterization, along with emphasis on the potential role of Se and SeCs as anti-cancer agents for lymphoma treatment. In addition, we have discussed various pros and cons associated with the usage of Se/SeCs for selectively targeting cancers including lymphomas.","PeriodicalId":93816,"journal":{"name":"SPG biomed","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84590065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Shimizu, Hidenobu Hayakawa, Nagisa Sasaki, Midori Takada, T. Okada, M. Kiyama
Height loss starting in middle age is reported to be an independent risk factor for cardiovascular mortality. Recent studies have revealed an inverse association between height and hypertension, but the influence of hypertension on height loss is unknown. Since hypertension is an established cardiovascular risk factor, clarifying the association between baseline hypertension and height loss could lead to an efficient tool to estimate the risk of mortality. A retrospective study of 11,154 Japanese aged 40–74 years was conducted. Height loss was defined as being in the highest quintile of annual height decrease (≥2.015 mm/year for men and ≥1.756 mm/year). Baseline height was significantly inversely associated with incident hypertension for men only. The adjusted odds ratio (OR) and 95% confidence interval (CI) for incident hypertension for each 1 standard deviation increment of height (5.9 cm for men and 5.6 cm for women) was 0.90 (0.84, 0.97) for men and 1.07 (0.91, 1.26) for women, respectively. We also found that baseline hypertension is independently positively associated with height loss for men only. The adjusted OR was 1.25 (1.11, 1.42) for men and 0.93 (0.71, 1.21) for women. These results might lead to an efficient tool for estimating the risk of height loss, which has been reported to be associated with a higher risk of mortality in adults.
{"title":"Association between Height and Hypertension: A Retrospective Study","authors":"Y. Shimizu, Hidenobu Hayakawa, Nagisa Sasaki, Midori Takada, T. Okada, M. Kiyama","doi":"10.3390/biomed2030024","DOIUrl":"https://doi.org/10.3390/biomed2030024","url":null,"abstract":"Height loss starting in middle age is reported to be an independent risk factor for cardiovascular mortality. Recent studies have revealed an inverse association between height and hypertension, but the influence of hypertension on height loss is unknown. Since hypertension is an established cardiovascular risk factor, clarifying the association between baseline hypertension and height loss could lead to an efficient tool to estimate the risk of mortality. A retrospective study of 11,154 Japanese aged 40–74 years was conducted. Height loss was defined as being in the highest quintile of annual height decrease (≥2.015 mm/year for men and ≥1.756 mm/year). Baseline height was significantly inversely associated with incident hypertension for men only. The adjusted odds ratio (OR) and 95% confidence interval (CI) for incident hypertension for each 1 standard deviation increment of height (5.9 cm for men and 5.6 cm for women) was 0.90 (0.84, 0.97) for men and 1.07 (0.91, 1.26) for women, respectively. We also found that baseline hypertension is independently positively associated with height loss for men only. The adjusted OR was 1.25 (1.11, 1.42) for men and 0.93 (0.71, 1.21) for women. These results might lead to an efficient tool for estimating the risk of height loss, which has been reported to be associated with a higher risk of mortality in adults.","PeriodicalId":93816,"journal":{"name":"SPG biomed","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84351276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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